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研究者情報

データ更新日:2020年04月01日

多田 隼人 (ただ はやと) 助教 TADA, Hayato

所属組織・役職等

附属病院

教育分野

所属研究室等

学歴

【出身大学院】
金沢大学大学院医学系研究科 博士課程 2011/06 修了
【出身大学】
金沢大学 医学部  医学科 2003/03 卒業

職歴

金沢大学大学院 先進予防医学研究科 循環予防医学(2017/10/01-)
金沢大学附属病院 救急部・循環器内科(2014/04/01-)
米国 ハーバード大学 ヒト遺伝学部門(2012/04/01-2014/03/31)
米国 Broadinstitute of MIT & Harvard(2012/04/01-2014/03/31)
米国 マサチューセッツ総合病院  ヒトゲノム研究所(2012/04/01-2014/03/31)
金沢大学附属病院 循環器内科(2006/04/01-2012/03/31)
福井循環器病院 循環器科(2005/04/01-2006/03/31)
厚生連高岡病院 内科(2004/04/01-2005/03/31)
金沢大学附属病院 内科(2003/04/01-2004/03/31)

生年月

1978年07月

所属学会

日本循環器学会 循環器専門医 北陸支部評議員(2018-2020)
日本内科学会 認定医、専門医、指導医
日本動脈硬化学会 評議員、指導医、専門医
日本救急医学会
日本心臓病学会
日本人類遺伝学会
米国人類遺伝学会
米国心臓協会
米国心臓病学会
欧州心臓病学会

学内委員会委員等

○CECTリンカーカンファレンス 委員(2016-2020)
○手術部運営委員会 委員(2014-2018)

受賞学術賞

○臨床薬理研究振興財団 研究奨励金(2020/01/09)
○2019年度井村臨床研究奨励賞(2019/12/14)
○公益財団法人 武田科学振興財団 2019年度研究助成(2019/11/12)
○第27回(2019年度)バイエル循環器病研究助成(2019/07/25)
○第12回金沢市医師会金沢医学館記念医学賞(2018/11/04)
○第30回 (平成29年度)小野医学研究助成(2018/06/01)
○平成29年度福田記念医療技術振興財団 論文表彰(2018/02/08)
○公益財団法人アステラス病態代謝研究会 研究助成金(2017/11/01)
○The 61st Annual Scientific Meeting of The Korean Society of Cardiology Young Investigator’s Award Competition Finalist(2017/10/12)
○2017年度日本心臓病学会YIA優秀賞(2017/09/29)
○日本循環器学会 第34回YIA Clinical Research部門 最優秀賞
○第30回日本小児脂質研究会 会長賞(2016/11/26)
○American Heart Association ATVB Travel Award for Young Investigators(2016/11/12)
○第14回(平成28年度) 榊原記念研究助成金(2016/11/01)
○平成28年度循環器疾患・糖尿病等生活習慣病対策実用化研究事業(AMED)(2016/10/04)
○10 th APSAVD YIA(2016/07/16)
○第13回日本心臓財団・アステラス・ファイザー「動脈硬化Update」研究助成 奨励賞
○武田科学振興財団 医学系研究奨励(2015/11/01)
○平成27年度 持田記念研究助成金(2015/09/01)
○日本動脈硬化学会17th International Atherosclerosis Society Educational Grant
○先進医薬研究振興財団 平成26年度(第13回)循環医学分野 若手研究者助成(2014/12/01)
○上原記念生命科学財団 研究助成金(2014/11/03)
○Banyu Foundation Research Grant 2014 -生活習慣病領域-(2014/11/01)
○第46回日本動脈硬化学会総会・学術集会 優秀ポスター賞
○日本循環器学会2011年度 留学支援助成
○日本動脈硬化学会 第20回若手研究者奨励賞 優秀賞
○日本動脈硬化学会16th International Atherosclerosis Society Educational Grant
○11th US Japan Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition. Finalist
○米国心臓協会Robert Levy Memorial Lecture(2009/11/15)
○第7回日本心臓財団・アステラス・ファイザー「動脈硬化Update」研究助成 優秀賞

専門分野

専門分野キーワード

研究課題

著書

  • Modern Physician 2018 単著 多田 隼人
  • 動脈硬化予防 2018 原著書 単著 多田隼人
  • The Lipid 2018 原著書 共著 多田隼人、野村章洋、川尻剛照、山岸正和
  • The Lipid 2018 原著書 共著 多田隼人、川尻剛照、山岸正和

論文

  • Anomalous origin with myocardial bridging in coronary artery: Stealth images in computed tomography Journal of the American College of Cardiology 60巻 23号 2012/12/11 
  • IMPACT OF OUT-STENT PLAQUE VOLUME ON IN-STENT INTIMAL HYPERPLASIA: RESULTS FROM SERIAL VOLUMETRIC ANALYSIS WITH HIGH-GAIN INTRAVASCULAR ULTRASOUND Tada, Hayato;Kawashiri, Masa-aki;Takabatake, Shu;Nakanishi, Chiaki;Hodatsu, Akihiko;Mori, Mika;Tsubokawa, Toshinari;Konno, Tetsuo;Hayashi, Kenshi;Uchiyama, Katsuharu;Nohara, Atsushi;Fujino, Noboru;Ino, Hidekazu;Yamagishi, Masakazu JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57巻 14号 E1976-E1976頁 2011
  • Impact of bezafibrate and atorvastatin on lipoprotein subclass in patients with type III hyperlipoproteinemia: Result from a crossover study Kawashiri, Masa-aki;Kobayashi, Junji;Nohara, Atsushi;Noguchi, Tohru;Tada, Hayato;Nakanishi, Chiaki;Inazu, Akihiro;Mabuchi, Hiroshi;Yamagishi, Masakazu CLINICA CHIMICA ACTA 412巻 42320号 1068-1075頁 2011
  • Statin Therapy Improves Fractional Catabolic Rate of LDL without Affecting Impaired VLDL and VLDL Remnant Catabolism in Homozygous FH Patient Due to PCSK9 Gene Mutation: Evidence from Kinetic Study with Stable Isotope Kawashiri, Masa-aki;Ikewaki, Katsunori;Tada, Hayato;Noguchi, Tohru;Nohara, Atsushi;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu CIRCULATION 126巻 21号 0-0頁 2012
  • Pulmonary hypertension associated with veno-occlusive disease in systemic sclerosis: Insight into the mechanism of resistance to vasodilator Journal of Cardiology Cases 5巻 1号 e44-e47頁 2012/02/01 

全て表示

  • Research update for articles published in EJCI in 2012 European Journal of Clinical Investigation 44巻 10号 1010-1023頁 2014/01/01 
  • Post-prandial remnant lipoprotein metabolism in autosomal recessive hypercholesterolaemia European Journal of Clinical Investigation 42巻 10号 1094-1099頁 2012/10/01 
  • Perfect correspondence of mitral valve perforation using real-time 3-dimensional transesophageal echocardiography Journal of the American College of Cardiology 59巻 21号 2012/05/22 
  • Novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic subjects Clinica Chimica Acta 413巻 42130号 537-543頁 2012/03/22 
  • Marked transient hypercholesterolemia caused by low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma Journal of Atherosclerosis and Thrombosis 21巻 12号 1326-1329頁 2014/01/01 
  • Impact of out-stent plaque volume on in-stent intimal hyperplasia: Results from serial volumetric analysis with high-gain intravascular ultrasound International Journal of Cardiology 158巻 2号 235-239頁 2012/07/12 
  • Impact of bilateral internal thoracic-to-epigastric artery communications on salvaging total lower limb ischemia Journal of the American College of Cardiology 58巻 6号 2011/08/02 
  • Expression and function of ephrin-B1 and its cognate receptor EphB2 in human abdominal aortic aneurysm International Journal of Vascular Medicine 2012巻 2012/09/19 
  • Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia American Journal of Cardiology 109巻 3号 364-369頁 2012/02/01 
  • Impact of combined lipid lowering with blood pressure control on coronary plaque regression: rationale and design of MILLION study Heart and Vessels 2014/06/04 
  • Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus: Results from a crossover study Atherosclerosis 217巻 1号 165-170頁 2011/07/01 
  • Altered metabolism of low-density lipoprotein and very-low-density lipoprotein remnant in autosomal recessive hypercholesterolemia results from stable isotope kinetic study in vivo Circulation: Cardiovascular Genetics 5巻 1号 35-41頁 2012/02/01 
  • A novel type of familial hypercholesterolemia: Double heterozygous mutations in LDL receptor and LDL receptor adaptor protein 1 gene Atherosclerosis 219巻 2号 663-666頁 2011/12/01 
  • Lack of Association Between Common p.T111I Variant in the Endothelial Lipase Gene and the Risk for Coronary Artery Disease in Familial Hypercholesterolemia: Insights From the Modulation of Phospholipids in the HDL Particles Tada, Hayato;Kawashiri, Masa-aki;Nakanishi, Chiaki;Tsubokawa, Toshinari;Konno, Tetsuo;Hayashi, Kenshi;Uchiyama, Katsuharu;Nohara, Atsushi;Fujino, Noboru;Ino, Hidekazu;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu CIRCULATION 124巻 21号 0-0頁 2011
  • Molecular genetic epidemiology of homozygous familial hypercholesterolemia in the Hokuriku district of Japan Mabuchi, Hiroshi;Nohara, Atsushi;Noguchi, Tohru;Kobayashi, Junji;Kawashiri, Masa-aki;Tada, Hayato;Nakanishi, Chiaki;Mori, Mika;Yamagishi, Masakazu;Inazu, Akihiro;Koizumi, Junji;Hokuriku FH Study Grp ATHEROSCLEROSIS 214巻 2号 404-407頁 2011
  • Impact of Impaired LDL Catabolism and Increased VLDL and VLDL Remnant Production on Hypercholesterolemia in Homozygous PCSK9 Gene Mutation: Evidence from Kinetic Study with Stable Isotope Kawashiri, Masa-aki;Ikewaki, Katsunori;Tada, Hayato;Noguchi, Tohru;Nohara, Atsushi;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu CIRCULATION 124巻 21号 0-0頁 2011
  • Altered Metabolism of Post-Prandial Remnant Lipoprotein Fractions in Autosomal Recessive Hypercholesterolemia Tada, Hayato;Kawashiri, Masa-aki;Nakano, Takamitsu;Nakajima, Katsuyuki;Tsubokawa, Toshinari;Konno, Tetsuo;Hayashi, Kenshi;Uchiyama, Katsuharu;Nohara, Atsushi;Fujino, Noboru;Ino, Hidekazu;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu CIRCULATION 124巻 21号 0-0頁 2011
  • MECHANISM OF ENHANCED MIGRATION OF CARDIAC PROGENITOR CELLS BY BONE MARROW-DERIVED MESENCHYMAL STEM CELLS: INSIGHTS FROM GENE EXPRESSION AND SECRETARY CYTOKINES Nakanishi, Chiaki;Takabatake, Shu;Tada, Hayato;Tubokawa, Toshinari;Kawashiri, Masaaki;Yamagishi, Masakazu JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57巻 14号 E1016-E1016頁 2011
  • IMPACT OF ELEVATED PCSK9 LEVELS ON REGULATION OF LDL-CHOLESTEROL AFTER STATIN TREATMENT: STUDY WITH DIFFERENT TYPES OF LIPID LOWERING DRUGS Kawashiri, Masa-aki;Nohara, Atsushi;Noguchi, Tohru;Tada, Hayato;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57巻 14号 E577-E577頁 2011
  • A Novel Type of Homozygous Familial Hypercholesterolemia: Double Heterozygous Mutations in LDL Receptor and LDL Receptor Adaptor Protein 1 Gene Tada, Hayato;Kawashiri, Masa-aki;Nakanishi, Chiaki;Tsubokawa, Toshinari;Konno, Tetsuo;Hayashi, Kenshi;Uchiyama, Katsuharu;Nohara, Atsushi;Fujino, Noboru;Ino, Hidekazu;Inazu, Akihiro;Kobayashi, Junji;Mabuchi, Hiroshi;Yamagishi, Masakazu CIRCULATION 124巻 21号 0-0頁 2011
  • Clinical whole exome sequencing in severe hypertriglyceridemia Clin Chim Acta 2019 査読有
  • Remnant lipoproteins and atherosclerotic cardiovascular disease Clin Chim Acta 2019 査読有
  • Impact of decreased ankle-brachial index on 30-day bleeding complications and long-term mortality in patients with acute coronary syndrome after percutaneous coronary intervention J Cardiol 2019 査読有
  • A Japanese case of familial hypercholesterolemia with a novel mutation in the LDLR gene Nagahara K, Hachiya R, Tada H, Okada H, Yamagishi M, Dobashi K, Mizuno K, Hasegawa Y Clin Pediatr Endocrinol 2019 査読有 原著論文
  • Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia Sci Rep.  2019 査読有 原著論文
  • Rare Protein-truncating Variants in APOB, Lower LDL-C, and Protection Against Coronary Heart Disease Circ Genom Precis Med 2019 査読有 原著論文
  • Genotypic and phenotypic features in homozygous familial hypercholesterolemia caused by proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation Atherosclerosis 2014 査読有 原著論文 研究論文(学術雑誌)
  • Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke Stroke 2014 査読有 原著論文 研究論文(学術雑誌)
  • Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease Circ Cardiovasc Genet 2014 査読有 原著論文
  • Efficacy of Low-Density Lipoprotein Apheresis in Salvaging Critical Limb Ischemia Induced by Acute Thrombotic Occlusion on Peripheral Artery Disease Ther Apher Dial 2015 査読有 原著論文
  • Assessment of coronary atherosclerosis in patients with familial hypercholesterolemia by coronary computed tomography angiography Am J Cardiol 2015 査読有 原著論文
  • Exome sequencing in suspected monogenic dyslipidemias Circ Cardiovasc Genet 2015 査読有 原著論文
  • Infantile Cases of Sitosterolaemia with Novel Mutations in the ABCG5 Gene: Extreme Hypercholesterolaemia is Exacerbated by Breastfeeding JIMD Rep 2015 査読有 原著論文
  • Extreme Contrast of Postprandial Remnant-Like Particles Formed in Abetalipoproteinemia and Homozygous Familial Hypobetalipoproteinemia JIMD Rep 2015 査読有 原著論文
  • Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene Atherosclerosis 2015 査読有 原著論文
  • Whole Exome Sequencing in Monogenic Dyslipidemias J Atheroscler Thromb 2015 査読有 総説
  • Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation Circ Arrhythm Electrophysiol 2015 査読有 原著論文
  • Clinical characteristics of Japanese patients with severe hypertriglyceridemia J Clin Lipidol 2015 査読有 原著論文
  • Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody Circ Cardiovasc Genet 2015 査読有 原著論文
  • Atrial fibrillation: an inherited cardiovascular disease--a commentary on genetics of atrial fibrillation: from families to genomes J Hum Genet 2016 総説
  • Whole exome sequencing combined with integrated variant annotation prediction identifies a causative myosin essential light chain variant in hypertrophic cardiomyopathy J Cardiol 2016 査読有 原著論文
  • Clinical characteristics of Japanese patients with severe hypertriglyceridemia J Clin Lipidol 2016 査読有 原著論文 研究論文(学術雑誌)
  • Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history European Heart Journal 2016 査読有 原著論文 研究論文(学術雑誌)
  • Lipoprotein(a) in Familial Hypercholesterolemia With Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gain-of-Function Mutations Circ J 2016 査読有 原著論文
  • A de novo mutation of the LDL receptor gene as the cause of familial hypercholesterolemia identified using whole exome sequencing Clin Chim Acta 2016 査読有 原著論文 研究論文(学術雑誌)
  • A Rare Coincidence of Sitosterolemia and Familial Mediterranean Fever Identified by Whole Exome Sequencing J Atheroscler Thromb 2016 査読有 原著論文 研究論文(学術雑誌)
  • Prevalence, clinical features, and prognosis of patients with extremely low high-density lipoprotein cholesterol J Clin Lipidol 2016 査読有 原著論文 研究論文(学術雑誌)
  • Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease Circ Res 2017 査読有
  • Effect of Reverse Vessel Remodeling on Regression of Coronary Atherosclerosis in Patients Treated With Aggressive Lipid- and Blood Pressure-Lowering Therapy - Insight From MILLION Study Circ J 2017 査読有
  • Do We Expect Any Pleiotropic Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition for Reducing Cardiovascular Events Beyond Low-Density Lipoprotein Cholesterol Reduction? Circ J 2017 査読有
  • Impact of Aging on High-sensitivity Cardiac Troponin T in Patients Suspected of Acute Myocardial Infarction Intern Med 2017 査読有
  • Huge Metastatic Gastrointestinal Stromal Tumor Occupying the Right Ventricle Circ J 2017 査読有
  • Impact of evolocumab treatment on low-density lipoprotein cholesterol levels in heterozygous familial hypercholesterolemic patients withdrawing from regular apheresis Atherosclerosis 2017 査読有
  • Assessments of Carotid Artery Plaque Burden in Patients With Familial Hypercholesterolemia Am J Cardiol 2017 査読有
  • Huge right ventricular mass lesion associated with genital malignant tumor: a case report J Med Case Rep 2017 査読有
  • Lipoprotein Apheresis for Sitosterolemia Ann Intern Med 2017 査読有
  • Exome-wide association study of plasma lipids in >300,000 individuals Nat Genet 2017 査読有 研究論文(学術雑誌)
  • Molecular and functional characterization of familial chylomicronemia syndrome Atherosclerosis 2018 査読有
  • Acute myocardial infarction in a 25-year-old woman with sitosterolemia J Clin Lipidol 2018 査読有
  • Prominent Tendon Xanthomas and Abdominal Aortic Aneurysm Associated with Cerebrotendinous Xanthomatosis Identified Using Whole Exome Sequencing Intern Med 2018 査読有
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nat Genet 2018 査読有 研究論文(学術雑誌)
  • Paradoxical impact of decreased low-density lipoprotein cholesterol level at baseline on the long-term prognosis in patients with acute coronary syndrome Heart Vessels 2018 査読有
  • Assessment of arterial stiffness in patients with familial hypercholesterolemia J Clin Lipidol 2018 査読有
  • Duration of cardiopulmonary resuscitation in patients without prehospital return of spontaneous circulation after out-of-hospital cardiac arrest: Results from a severity stratification analysis Resuscitation 2018 査読有
  • Aortic Root Calcification Score as an Independent Factor for Predicting Major Adverse Cardiac Events in Familial Hypercholesterolemia J Atheroscler Thromb 2018 査読有
  • Unsolved Antiatherogenic Mechanism of n-3 Polyunsaturated Fatty Acids Circ J 2018 査読有
  • Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol J Atheroscler Thromb 2018 査読有
  • Additive Prognostic Value of Carotid Plaque Score to Enhance the Age, Creatinine, and Ejection Fraction Score in Patients with Acute Coronary Syndrome J Atheroscler Thromb 2018 査読有
  • Late Gadolinium Enhancement for Prediction of Mutation-Positive Hypertrophic Cardiomyopathy on the Basis of Panel-Wide Sequencing Circ J 2018 査読有
  • Impact of B-Type Natriuretic Peptide Level on Risk Stratification of Thromboembolism and Death in Patients With Nonvalvular Atrial Fibrillation - The Hokuriku-Plus AF Registry Circ J 2018 査読有
  • Remnant-like particles and coronary artery disease in familial hypercholesterolemia Clin Chim Acta 2018 査読有
  • Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports J Med Case Rep 2018 査読有
  • Mendelian randomization: Its impact on cardiovascular disease J Cardiol 2018 査読有
  • Effects of prehospital epinephrine administration on neurologically intact survival in bystander-witnessed out-of-hospital cardiac arrest patients with non-shockable rhythm depend on prehospital cardiopulmonary resuscitation duration required to hospital arrival Heart Vessels 2018 査読有
  • Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia J Atheroscler Thromb 2018 査読有
  • First case of sitosterolemia caused by double heterozygous mutations in ABCG5 and ABCG8 genes J Clin Lipidol 2018 査読有
  • Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease J Atheroscler Thromb 2018 査読有
  • Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography Heart Vessels 2018 査読有
  • Serum triglycerides predict first cardiovascular events in diabetic patients with hypercholesterolemia and retinopathy Eur J Prev Cardiol 2018 査読有
  • Spontaneous Isolated Superior Mesenteric Artery Dissection Requiring Emergent Surgery Intern Med 2018 査読有
  • Oligogenic familial hypercholesterolemia, LDL cholesterol, and coronary artery disease J Clin Lipidol 2018 査読有
  • Low Baseline High-Sensitive C-Reactive Protein is Associated with Coronary Atherosclerosis Regression: Insights from the MILLION Study J Atheroscler Thromb 2018 査読有
  • Serum Triglycerides and Atherosclerotic Cardiovascular Disease: Insights from Clinical and Genetic Studies Nutrients 2018 査読有
  • Statin Intolerance and Suboptimal Statin Therapy J Atheroscler Thromb 2018 査読有
  • Associations between questionnaires on lifestyle and atherosclerotic cardiovascular disease in a Japanese general population: A cross-sectional study PLoS One 2018 査読有
  • Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation Heart Rhythm 2018 査読有
  • Impact of genetic testing on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia (GenTLe-FH): a randomised waiting list controlled open-label study protocol BMJ Open 2018 査読有 原著論文
  • Genetic Variations, Triglycerides, and Atherosclerotic Disease J Atheroscler Thromb 2019 査読有
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity 2018/01/01
  • Lipid Management in a Japanese Community:Attainment Rate of Target Set by the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012 2017 査読有 原著論文 研究論文(学術雑誌)
  • Impact of clinical signs and genetic diagnosis of familial hypercholesterolaemia on the prevalence of coronary artery disease in patients with severe hypercholesterolaemia 2017 査読有 研究論文(学術雑誌)
  • Renal glucosuria is not associated with atherosclerotic cardiovascular disease outcome in a general Japanese community 2017 査読有 原著論文 研究論文(学術雑誌)
  • Metabolic Mediators of the Effects of Family History and Genetic Risk Score on Coronary Heart Disease-Findings From the Malmö Diet and Cancer Study 2017 査読有 原著論文 研究論文(学術雑誌)

講演・口頭発表等

  • ゲノムから展望するPCSK-9の意義(会議名:CVIT2019 )(2019/09/18)
  • 31年にわたるあらゆる環境器集学的治療により生存し得た重症家族性高コレステロール血症の一例(会議名:第67回日本心臓病学会学術集会)(2019/09/13)
  • Comprehensive genetic analyses illuminate a causal association between LDL cholesterol and atherosclerotic cardiovascular disease: (会議名:BCVR)(2019/09/06)
  • 遺伝子研究・臨床研究から考えるLDL-C低下療法:一体どこまで下げれば良いのか?どこまで下げても安全なのか?(会議名:第51回 日本動脈硬化学会総会・学術集会)(2019/07/11)
  • 遺伝学から考える動脈硬化性疾患予防・治療、FH & Beyond(会議名:第51回 日本動脈硬化学会総会・学術集会)(2019/07/11)

全て表示

  • Validation of clinical diagnostic criteria of familial hypercholesterolemia in Japan: Evidence from a comprehensive genetic analysis(会議名:第83回 日本循環器学会学術集会)(2019/03/29)
  • ヒトゲノム情報から考える冠動脈疾患治療・予防 (会議名:第83回 日本循環器学会学術集会)(2019/03/29)
  • Impact of ABCG5/8 genetic variants on coronary heart disease(会議名:第83回 日本循環器学会学術集会)(2019/03/29)
  • Beneficial effect of ezetimibe-atorvastatin combination therapy in patients with a mutation in ABCG5 or ABCG8 gene (会議名:米国心臓協会)(2018/11/10)
  • Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia (会議名:欧州心臓病学会学術集会)(2018/08/25)
  • 超積極的LDL-C低下療法のススメ:臨床エビデンス・遺伝学的エビデンスからの考察(会議名:第32回日本冠疾患学会学術集会)(2018/11/17)
  • 循環器ゲノム医療の実践:脂質異常症と冠動脈疾患(会議名:第66回日本心臓病学会学術集会)(2018/09/07)
  • 動脈硬化イメージング・極端な症例から学ぶFHに対する至適治療開始時期の考察(会議名:第66回日本心臓病学会学術集会)(2018/09/07)
  • Heterozygous mutations of ABCG5/8 and risk for coronary heart disease(会議名:第50回日本動脈硬化学会総会)(2018/07/12)
  • Contribution of PCSK9 in hyper and hypo LDL cholesterolemia: Insights from comprehensive genetic analyses in patients with FH and FHBL(会議名:第50回日本動脈硬化学会総会)(2018/07/11)

芸術・フィールドワーク

特許

○冠動脈疾患の罹患リスクの判定方法又は判定の補助方法

共同研究希望テーマ

科研費

○基盤研究(C)「網羅的遺伝子解析によるリポ蛋白(a)代謝新規関連分子の探索とその機能解析」(2019-2021) 代表者
○研究活動スタート支援「家族性高コレステロール血症の新規原因遺伝子の網羅的解析」(2014-2015)
○若手研究(B)「家族性高コレステロール血症の新規原因遺伝子の網羅的解析」(2012-2013) 代表者
○若手研究(B)「網羅的遺伝子解析による新規LDLコレステロール代謝関連分子Xの発見とその機能解析」(2016-2018) 代表者

学域・学類担当授業科目

大学院担当授業科目

○臓器機能制御学特論(2017)
○臓器機能制御学特論(2017)
○メディカルサイエンスセミナー(2016)
○臓器機能制御学特論(2016)
○臓器機能制御学特論(2016)

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