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Researcher Information

last modified：2024/04/19

Assistant Professor　KOJO, Satoshi

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Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences

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Laboratory

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  • 　Impaired IFN-gamma production of V(alpha)24NKT cells in non-remitting sarcoidosis　S Kobayashi,Y Kaneko,K Seino,Y Yamada,S Motohashi,J Koike,K Sugaya,T Kuriyama,S Asano,T Tsuda,H Wakao,M Harada,S Kojo,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　16　2　215　2004/02
  • 　Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch　E Kondo,H Wakao,H Koseki,T Takemori,S Kojo,M Harada,M Takahashi,S Sakata,C Shimizu,T Ito,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　15　3　393　2003/03
  • 　Identification of Th2-type suppressor T cells among in vivo expanded ocular T cells in mice with experimental autoimmune uveoretinitis　H Keino,M Takeuchi,J Suzuki,S Kojo,J Sakai,K Nishioka,T Sumida,M Usui　CLINICAL AND EXPERIMENTAL IMMUNOLOGY　124　1　1　2001/04
  • 　Analysis of T cell receptor V-beta gene expression and clonality in bronchoalveolar fluid lymphocytes from a patient with chronic eosinophilic pneumonitis　N Shimizudani,H Murata,S Kojo,Y Adachi,H Keino,F Tsuchida,M Sumida,M Kawamata,T Sumida,T Matsuoka　LUNG　179　1　31　2001/01
  • 　Low Expression of Soluble CD1d Patients with Rheumatoid Arthritis.　Goto, D,Kojo, S,Matsumoto, I,Ito, S,Tsutsumi, A,Sumida, T　Arthritis Rheum　50　S528　2004/01

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  • 　Suppression of IgE antibody responses by NKT cells-mechanisms of NKT cell-mediated regulatory function　Satoshi Kojo,Michishige Harada,Ken-ichiro Seino,Masaru Taniguchi　International Congress Series　1285　179　2005/11
  • 　The importance of CD25(+)CD4(+) regulatory T cells in mouse hepatic allograft tolerance　Jiang, X,M Morita,A Sugioka,M Harada,S Kojo,H Wakao,H Watarai,N Ohkohchi,M Taniguchi,KI Seino　LIVER TRANSPLANTATION　12　7　1112　2006/07
  • 　Expression of tristetraprolin (G0S24) mRNA, a regulator of tumor necrosis factor-alpha production, in synovial tissues of patients with rheumatoid arthritis　A Tsutsumi,E Suzuki,Y Adachi,H Murata,D Goto,S Kojo,Matsumoto, I,L Zhong,H Nakamura,T Sumida　JOURNAL OF RHEUMATOLOGY　31　6　1044　2004/06
  • 　V alpha 14 NKT cell-triggered IFN-gamma production by Gr-1(+)CD11b(+) cells mediates early graft loss of syngeneic transplanted islets　Y Yasunami,S Kojo,H Kitamura,A Toyofuku,M Satoh,M Nakano,K Nabeyama,Y Nakamura,N Matsuoka,S Ikeda,M Tanaka,J Ono,N Nagata,O Ohara,M Taniguchi　JOURNAL OF EXPERIMENTAL MEDICINE　202　7　913　2005/10
  • 　Induction of regulatory properties in dendritic cells by V alpha 14 NKT cells　S Kojo,K Seino,M Harada,H Watarai,H Wakao,T Uchida,T Nakayama,M Taniguchi　JOURNAL OF IMMUNOLOGY　175　6　3648　2005/09
  • 　Cutting edge: Critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance　XF Jiang,T Shimaoka,S Kojo,M Harada,H Watarai,H Wakao,N Ohkohchi,S Yonehara,M Taniguchi,K Seino　JOURNAL OF IMMUNOLOGY　175　4　2051　2005/08
  • 　Dysfunction of T cell receptor AV24AJ18+,BV11+double-negative regulatory natural killer T cells in autoimmune diseases　S Kojo,Y Adachi,H Keino,M Taniguchi,T Sumida　ARTHRITIS AND RHEUMATISM　44　5　1127　2001/05
  • 　Regulatory function of NKT cells in the protection of autoimmune disease development　Taniguchi Masaru,Nakagawa Ryusuke,Kojo Satoshi,Watarai Hiroshi　JOURNAL OF NEUROIMMUNOLOGY　178　14　2006/09
  • 　G0S24, a gene that regulates TNFa production,is highly expressed in synovial tissue from patients with rheumatoid arthritis.　Tsutsumi, A,Adachi, Y,Murata, H,Kojo, S,Shibuya, K,Nakamura, H,and,Sumida T,住田, 孝之　J. Rheumatol.　31　6　1044-9　2004/01
  • 　Conserved CDR 3 region of T cell receptor BV gene in lymphocytes from bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis　N Shimizudani,H Murata,H Keino,S Kojo,H Nakamura,Y Morishima,T Sakamoto,M Ohtsuka,K Sekisawa,M Sumida,T Sumida,T Matsuoka　CLINICAL AND EXPERIMENTAL IMMUNOLOGY　129　1　140　2002/07
  • 　The expression and function of CD1d variants in patients with autoimmune disease.　Daisuke Goto,Yohei Yoshiga,Satoshi Kojo,Isao Matsumoto,Satoshi Ito,Akito Tsutsumi,Takayuki Sumida　ARTHRITIS AND RHEUMATISM　54　9　S405　2006/09
  • 　Alternative splicing forms of the human CD1D gene in mononuclear cells　S Kojo,Y Adachi,A Tsutsumi,T Sumida　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　276　1　107　2000/09
  • 　The regulatory role of V alpha 14 NKT cells in innate and acquired immune response　Taniguchi M,Harada M,Kojo S,Nakayama T,Wakao H　Annual Review of Immunology　21　483　2003　
  • 　Down-regulation of the invariant V alpha 14 antigen receptor in NKT cells upon activation　M Harada,K Seino,H Wakao,S Sakata,Y Ishizuka,T Ito,S Kojo,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　16　2　241　2004/02
  • 　α-MSH stimulation contributes to TGF-β1 production via MC1R-MITF signaling pathway in melanoma cell　Hayashi Erika,Hachiya Kaori,Kojo Satoshi,Baghdadi Muhammad,Takeuchi Shintaro,Yamanaka Hiroyuki,Abe Hirotak,Wada Haruka,Seino Ken-ichiro　Inflammation and Regeneration　35　5　244　2015
  • 　Mouse models of human INAD by Pla2g6 deficiency.　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　Histology and histopathology　28　8　965　2013/08
  • 　Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.　Haruka Wada,Satoshi Kojo,Chie Kusama,Naoki Okamoto,Yorino Sato,Bunpei Ishizuka,Ken-ichiro Seino　International immunology　23　1　65　2011/01
  • 　Role of gamma delta T cells in the regulation of HTLV-1 infection　Sato, Tomoo,Muto, Masato,Araya, Natsumi,Kojo, Satoshi,Naoko, Ariyoshi,Maekawa, Ryuji,Utsunomiya, Atae,Seino, Ken-ichiro,Yamano, Yoshihisa　Journal of Neurovirology　18　100　2012
  • 　Mechanism of NKT cell-mediated transplant tolerance　X. Jiang,S. Kojo,M. Harada,N. Ohkohchi,M. Taniguchi,K.-I. Seino　AMERICAN JOURNAL OF TRANSPLANTATION　7　6　1482　2007/06
  • 　Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire.　Nyambayar Dashtsoodol,Tomokuni Shigeura,Ritsuko Ozawa,Michishige Harada,Satoshi Kojo,Takashi Watanabe,Haruhiko Koseki,Manabu Nakayama,Osamu Ohara,Masaru Taniguchi　PloS one　11　4　e0153347　2016
  • 　Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.　Satoshi Kojo,Nighat Yasmin,Sawako Muroi,Mari Tenno,Ichiro Taniuchi　Nature communications　9　1　3593　2018/09/05
  • 　Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.　Satoshi Kojo,Hirokazu Tanaka,Takaho A Endo,Sawako Muroi,Ye Liu,Wooseok Seo,Mari Tenno,Kiyokazu Kakugawa,Yoshinori Naoe,Krutula Nair,Kazuyo Moro,Yoshinori Katsuragi,Akinori Kanai,Toshiya Inaba,Takeshi Egawa,Byrappa Venkatesh,Aki Minoda,Ryo Kominami,Ichiro Taniuchi　Nature communications　8　1　702　2017/09/26
  • 　Alternative pathway for the development of Vα14+ NKT cells directly from CD4-CD8- thymocytes that bypasses the CD4+CD8+ stage.　Nyambayar Dashtsoodol,Tomokuni Shigeura,Minako Aihara,Ritsuko Ozawa,Satoshi Kojo,Michishige Harada,Takaho A Endo,Takashi Watanabe,Osamu Ohara,Masaru Taniguchi　Nature immunology　18　3　274　2017/03
  • 　Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.　Hiroya Kudo,Haruka Wada,Hajime Sasaki,Hyuma Tsuji,Ryo Otsuka,Muhammad Baghdadi,Satoshi Kojo,Tatsuya Chikaraishi,Ken-ichiro Seino　PloS one　9　10　e111826　2014
  • 　Side population is increased in paclitaxel-resistant ovarian cancer cell lines regardless of resistance to cisplatin.　Yoichi Kobayashi,Ken-Ichiro Seino,Shinji Hosonuma,Tatsuru Ohara,Hiroaki Itamochi,Seiji Isonishi,Tsunekazu Kita,Haruka Wada,Satoshi Kojo,Kazushige Kiguchi　Gynecologic oncology　121　2　390　2011/05/01
  • 　Clinical significance of side population in ovarian cancer cells.　Shinji Hosonuma,Yoichi Kobayashi,Satoshi Kojo,Haruka Wada,Ken-ichiro Seino,Kazushige Kiguchi,Bunpei Ishizuka　Human cell　24　1　9　2011/03
  • 　Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1.　Satoshi Kojo,Chris Elly,Yohsuke Harada,Wallace Y Langdon,Mitchell Kronenberg,Yun-Cai Liu　Proceedings of the National Academy of Sciences of the United States of America　106　42　17847　2009/10/20
  • 　免疫システム開発 免疫細胞発生におけるRunx転写因子の役割(Immunosystem development Roles of Runx Transcription Factors In Immune Cell Development)　Taniuchi Ichiro,Kojo Satoshi,Ebihara Takashi,Seo Wooseok,Tenno Mari　日本免疫学会総会・学術集会記録　46　Proceedings　S8　2017/12
  • 　Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.　Mari Tenno,Satoshi Kojo,Divine-Fondzenyuy Lawir,Isabell Hess,Katsuyuki Shiroguchi,Takashi Ebihara,Takaho A Endo,Sawako Muroi,Rumi Satoh,Hiroshi Kawamoto,Thomas Boehm,Ichiro Taniuchi　The Journal of experimental medicine　215　2　595　2018/02/05
  • 　自然リンパ球(2) (ILC1,2,3) Runxタンパク質はILC2の構成的活性を抑制し活性化後のILC2枯渇を予防する(Innate Lymphocyte (ILC1,2,3) Runx proteins suppress constitutive activity of ILC2 and prevent ILC2 exhaustion after activation)　Ebihara Takashi,Kojo Satoshi,Taniuchi Ishiro　日本免疫学会総会・学術集会記録　46　Proceedings　3　2017/12
  • 　Essential Roles of SATB1 in Specifying T Lymphocyte Subsets.　Kiyokazu Kakugawa,Satoshi Kojo,Hirokazu Tanaka,Wooseok Seo,Takaho A Endo,Yohko Kitagawa,Sawako Muroi,Mari Tenno,Nighat Yasmin,Yoshinori Kohwi,Shimon Sakaguchi,Terumi Kowhi-Shigematsu,Ichiro Taniuchi　Cell reports　19　6　1176　2017/05/09
  • 　Transcriptional regulator Bhlhe40 works as a cofactor of T-bet in the regulation of IFN-γ production in iNKT cells.　Masatoshi Kanda,Hiroyuki Yamanaka,Satoshi Kojo,Yuu Usui,Hiroaki Honda,Yusuke Sotomaru,Michishige Harada,Masaru Taniguchi,Nao Suzuki,Tatsuya Atsumi,Haruka Wada,Muhammad Baghdadi,Ken-Ichiro Seino　Proceedings of the National Academy of Sciences of the United States of America　113　24　E3394-402　2016/06/14
  • 　Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy.　Masaru Taniguchi,Michishige Harada,Nyambayar Dashtsoodol,Satoshi Kojo　Proceedings of the Japan Academy. Series B, Physical and biological sciences　91　7　292　2015
  • 　Establishment of an improved mouse model for infantile neuroaxonal dystrophy that shows early disease onset and bears a point mutation in Pla2g6.　Haruka Wada,Takuwa Yasuda,Ikuo Miura,Kazuhiko Watabe,Chika Sawa,Hajime Kamijuku,Satoshi Kojo,Masaru Taniguchi,Ichizo Nishino,Shigeharu Wakana,Hisahiro Yoshida,Ken-ichiro Seino　The American journal of pathology　175　6　2257　2009/12
  • 　Suppressor turns into helper　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　IMMUNOTHERAPY　1　5　737　2009/09
  • 　Specific requirement of C-terminal Zn finger motifs in Bcl11b transcription factor for lineage dissection upon receiving positive selection signals in the thymus　Kojo, S.,Seo, W.,Muroi, S.,Taniuchi, I　European Journal of Immunology　46　260　2016
  • 　Research highlights: Immunomodulation.　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　Immunotherapy　1　5　737　2009/09
  • 　Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.　Chizuko Miyamoto,Satoshi Kojo,Motoi Yamashita,Kazuyo Moro,Georges Lacaud,Katsuyuki Shiroguchi,Ichiro Taniuchi,Takashi Ebihara　Nature communications　10　1　447　2019/01/25
  • 　Author Correction: Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.　Chizuko Miyamoto,Satoshi Kojo,Motoi Yamashita,Kazuyo Moro,Georges Lacaud,Katsuyuki Shiroguchi,Ichiro Taniuchi,Takashi Ebihara　Nature communications　10　1　1075　2019/03/01
  • 　Constitutive CD8 expression drives innate CD8+ T-cell differentiation via induction of iNKT2 cells.　Satoshi Kojo,Michiko Ohno-Oishi,Hisashi Wada,Sebastian Nieke,Wooseok Seo,Sawako Muroi,Ichiro Taniuchi　Life science alliance　3　2　e202000642　2020/02　
  • 　Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity.　Wooseok Seo,Kanako Shimizu,Satoshi Kojo,Arinze Okeke,Terumi Kohwi-Shigematsu,Shin-Ichiro Fujii,Ichiro Taniuchi　Nature communications　11　1　1562　2020/03/26
  • 　Photoswitching CD1d-restriction of TCR by α-GalCer analogs with azobenzene in the middle of acyl chain　Takashi Kanamori,Daisuke Nakabun,Satoshi Kojo,Hiroshi Watarai,Hideya Yuasa　Journal of Photochemistry and Photobiology A: Chemistry　451　115501　2024/06
  • 　Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development.　Keiko Ono,Tomohisa Sujino,Kentaro Miyamoto,Yosuke Harada,Satoshi Kojo,Yusuke Yoshimatsu,Shun Tanemoto,Yuzo Koda,Jiawen Zheng,Kazutoshi Sayama,Tsuyoshi Koide,Toshiaki Teratani,Yohei Mikami,Kaoru Takabayashi,Nobuhiro Nakamoto,Naoki Hosoe,Mariya London,Haruhiko Ogata,Daniel Mucida,Ichiro Taniuchi,Takanori Kanai　Nature communications　14　1　5152　2023/08/24

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