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Researcher Information

last modified:2018/04/02

Associate Professor OKAJIMA Masaki

Mail Laboratory Website

Faculty, Affiliation

University Hospital

College and School Educational Field

Division of Environmental Science, Graduate School of Medical Scienc
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Intensive care Unit TEL:076-265-2000 FAX:076-234-4339

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor 200103 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University 199603

Career

Kanazawa University Hospital(1996/04/01-1997/03/31)
Kanazawa Municipal Hospital(1997/04/01-1998/03/31)
Kanazawa University Hospital(1998/04/01-1999/09/30)
Public Central Hospital of Matto Ishikawa(1999/10/01-2001/08/30)
Institut de Cardiologie de Montreal Physiology(2001/09/01-2003/06/30)
Kanazawa University Hospital Critical Care Unit Assistant Professor(2003/07/01-2005/04/30)
Kanazawa University Hospital Department of Cardiology(2005/05/01-2007/03/31)
Kanazawa University Hospital Department of Cardiology Assistant Professor(2007/04/01-2007/06/30)
Kanazawa University Graduate School of Medicine Department of Disease Control and Homeostasis Assistant Professor(2007/07/01-2007/10/31)
Kanazawa University Hospital Department of Cardiology Assistant Professor(2007/11/01-2008/03/31)
Kanazawa University Graduate School of Medicine Assistant Professor(2008/04/01-2008/09/30)
Kanazawa University Hospital Critical Care Unit Assistant Professor(2008/10/01-2010/04/30)
Kanazawa University Hospital Intensive Care Unit Assistant Professor(2010/05/01-2011/03/31)
Kanazawa University Hospital Intensive Care Unit vice director(2011/04/01-2012/01/31)
Kanazawa University Hospital Intensive Care Unit clinical associate professor(2012/02/01-2012/03/31)
Kanazawa University Hospital Intensive Care Unit Assistant Professor(2012/04/01-)

Year & Month of Birth

1971/02

Academic Society

The japanese Circulation Society
The japanese Society of Internal Medicine
The Japanese Society of Intensive Care Medicine
The Japanese Society of Intensive Care Medicine
Japanese Association for Acute Medicine
Japanese Society of Aeromedical Services
Japanese Society of Travel Medicine

Award


Specialities

Emergency medicine、Cardiovascular medicine

Speciality Keywords

Unfolded protein response beta receptor antagonist Takotsubo cardiomyopathy Arrhythmia coronary vascular physiology

Research Themes

myocardial ischemia and cytokine

Myocardial ischemia and endothelin

Ischemia-reperfusion and UPR

Sepsis and UPR

Books

Papers

  •  beta-adrenergic receptor blockade impairs NO-dependent dilation of large coronary arteries during exercise. Okajima M, Takamura M, Vequaud P, Parent R, Lavallee M. Am J Physiol Hear Circ Physiol. 284 2 H501-H510 2003
  •  Pathophysiological plasma ET-1 levels antagonize beta-adrenergic dilation of coronary resistance vessels in conscious dogs. Masaki Okajima, Robert Parent, Eric Thorin, Michel Lavallee. Am J Physiol Hear Circ Physiol. 287 4  H1476-H1483 2004
  •  The attitudes of Japanese high school students toward cardiopulmonary resuscitation. Omi W, Taniguchi T, Kaburaki T, Okajima M, Takamura M, Noda T, Ohta K, Itoh H, Goto Y, Kaneko S, Inaba H. RESUSCITATION 78 3 340-345 2008
  •  Altered interaction between plasminogen activator inhibitor type 1 activity and sympathetic nerve activity with aging. Otowa K, Takamura M, Murai H, Maruyama M, Nakano M, Ikeda T, Kobayashi D, Ootsuji H, Okajima M, Furushou H, Yuasa T, Takata S, Kaneko S. Circ J. 72 3 458-62 2008
  •  Current Status of Anticoagulation Therapy for Elderly Atrial Fibrillation Patients in Japan: From Hokuriku Atrial Fibrillation Trial. Furusho H, Takamura M, Takata S, Sakagami S, Hirazawa M, Kato T, Murai H, Okajima M, Kaneko S. Circ J. 72 12 2058-2061 2008

show all

  •  Doppler tissue analysis of atrial electromechanical coupling in paroxysmal atrial fibrillation. Omi W, Nagai H, Takamura M, Okura S, Okajima M, Furusho H, Maruyama M, Sakagami S, Takata S, Kaneko S. J Am Soc Echocardiogr Off Publ Am Soc Echocardiogr. 18 1 39-44 2005
  •  Impact of severe earthquake on the occurrence of acute coronary syndrome and stroke in a rural area of Japan. Tsuchida M, Kawashiri MA, Teramoto R, Takata M, Sakata K, Omi W, Okajima M, Takamura M, Ino H, Kita Y, Takegoshi T, Inaba H, Yamagishi M. Circ J. 73 7 1243-1247 2009
  •  Altered firing pattern of single-unit muscle sympathetic nerve activity during handgrip exercise in chronic heart failure. Murai H, Takamura M, Maruyama M, Nakano M, Ikeda T, Kobayashi D, Otowa K, Ootsuji H, Okajima M, Furusho H, Takata S, Kaneko S.  J Physiol. 587 2613-2622 2009
  •  The Rho/Rho-kinase Systems Are Involved in Rapid Pacing-induced Changes of Atrial Refractory Period in a Canine Model. Furusho H, Sakagami S, Takamura M, Kitano K, Abe T, Hirazawa M, Usui S, Okajima M, Saeki T, Maruyama M, Kaneko S, Takata S. J Arrhythmia. 22 167-173 2006
  •  The electrolarynx as a communication tool for mechanically ventilated critically ill patients: a prospective feasibility study. Sato K Okajima M Taniguchi T Intensive care medicine 42 8 1299-300 2016
  •  Landiolol, an ultra-short-acting β1-blocker, is useful for managing supraventricular tachyarrhythmias in sepsis. Okajima, Masaki Takamura, Masayuki Taniguchi, Takumi World journal of critical care medicine 4 3 251-7 2015
  •  The electrolarynx as a communication tool for mechanically ventilated critically ill patients: a prospective feasibility study Koji Sato · Masaki Okajima · Takumi Taniguchi Intensive Care Medicine 42 8 1299-300 2016/05/19
  •  Benidipine reduces ischemia reperfusion-induced systemic oxidative stress through suppression of aldosterone production in mice Ohtani, Keisuke; Usui, Soichiro; Kaneko, Shuichi; Takashima, Shinichiro; Kitano, Katsunori; Yamamoto, Kanako; Okajima, Masaki; Furusho, Hiroshi; Takamura, Masayuki Hypertension Research 35 3 287-294 2012/03/01 
  •  Attitudes to bystander cardiopulmonary resuscitation in Japan in 2010 Taniguchi, Takumi; Sato, Koji; Fujita, Takashi; Okajima, Masaki; Takamura, Masayuki Circulation Journal 76 5 1130-1135 2012/04/30 
  •  Attitudes toward automated external defibrillator use in Japan in 2011 Taniguchi, Takumi; Sato, Koji; Kurita, Akihide; Noda, Toru; Okajima, Masaki Journal of Anesthesia 28 1 34-37 2014/02/01 
  •  Augmented single-unit muscle sympathetic nerve activity in heart failure with chronic atrial fibrillation Ikeda, Tatsunori; Murai, Hisayoshi; Kaneko, Shuichi; Usui, Soichiro; Kobayashi, Daisuke; Nakano, Manabu; Ikeda, Keiko; Takashima, Shinichiro; Kato, Takeshi; Okajima, Masaki; Furusho, Hiroshi; Takamura, Masayuki Journal of Physiology 590 3 509-518 2012/02/01 
  •  Effects of acute low-dose ethanol on inflammatory reactions to endotoxin-induced shock in rats Ajisaka, Hideyuki; Okajima, Masaki; Goto, Yoshikazu; Taniguchi, Takumi; Inaba, Hideo Journal of Toxicological Sciences 37 3 649-654 2012/06/01 
  •  Efficacy of endotoxin adsorption therapy (polymyxin B hemoperfusion) for methicillin-resistant Staphylococcus aureus toxic shock syndrome: A case report about five patients Taniguchi, Takumi; Sato, Koji; Kurita, Akihide; Noda, Toru; Okajima, Masaki Minerva Anestesiologica 79 7 758-761 2013/07/01 
  •  Magnetic resonance imaging in a patient with an implantable cardiac defibrillator Furusho, Hiroshi; Kusayama, Takashi; Chikata, Akio; Kobayashi, Daisuke; Murai, Hisayoshi; Usui, Soichiro; Okajima, Masaki; Kaneko, Shuichi; Yamagishi, Masakazu; Takamura, Masayuki Journal of Arrhythmia 28 6 353-355 2012/12/01 
  •  Effects of Long-Term Administration of Dexmedetomidine on Inflammatory Responses in Patients with Severe Sepsis Taniguchi, Takumi;Kurita, Akihide;Sato, Koji;Fujita, Takashi;Sakata, Kenji;Okajima, Masaki CIRCULATION 124 21 0-0 2011
  •  successful treatment of exertional heat stroke using continuous plasma diafiltration Inoue N, Sato A, Ikawa Y, Shimizu M, Okajima M, Taniguchi T, Yachie A J Clin Apher 32 5 490-492 2016/10
  •  Usefulness of continuous electroencephalography in severe heat stroke complicated with multi–organ failure: a case report Satoaki Hachiya, Masaki Okajima, Miho Nakamura, Kouji Sato, Yoshinao Koshida, Toru Noda, Takumi Taniguchi JJAAM 27 125-129 2016/06
  •  Effects of acute low-dose ethanol on inflammatory reactions to endotoxin-induced shock in rats. Ajisaka H, Okajima M, Goto Y, Taniguchi T, Inaba H J Toxicol Sci 37 3 649-54 2012
  •  Augmented single-unit muscle sympathetic nerve activity in heart failure with chronic atrial fibrillation.  Ikeda T, Murai H, Kaneko S, Usui S, Kobayashi D, Nakano M, Ikeda K, Takashima S, Kato T, Okajima M, Furusho H, Takamura M. J Physiol 590 509-18 2012
  •  Benidipine Reduced Ischemia Reperfusion Induced Systemic Oxidative Stress through Suppression of Aldosterone Production in Mice. Keisuke Ohtani, Soichiro Usui, Shuichi Kaneko, Shin-ichiro Takashima, Katsunori Kitano, Kanako Yamamoto, Masaki Okajima, Hiroshi Furusho, Masayuki Takamura. Hypertens Res. 35 3 287-94 2012
  •  Altered hepatic gene expression profiles associated with myocardial ischemia. Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, Horimoto K, Takamura M.  Circ Cardiovasc Genet 1 3 68-77 2010
  •  Sodium 4-phenylbutylate protects against myocardial ischemia-reperfusion injury by reducing unfolded protein response-mediated apoptosis in mice. M Okajima, M Takamura, S Usui, T Taniguchi SK. Crit Care. 2010
  •  Attitudes to bystander cardiopulmonary resuscitation in Japan in 2010. Taniguchi T, Sato K, Fujita T, Okajima M, Takamura M Circ J. 76 5 1130-5 2012
  •  Elimination of teicoplanin by adsorption to the filter membrane during haemodiafiltration: screening experiments for linezolid, teicoplanin and vancomycin followed by in vitro haemodiafiltration models for teicoplanin. Shiraishi Y, Okajima M, Sai Y, Miyamoto K, Inaba H. Anaesth Intensive Care.  40 3 442-9 2012
  •  DEXMEDETOMIDINE, ALPHA-2 ADRENERGIC RECEPTOR AGONIST, IS A SUITABLE DRUG FOR THE MANAGEMENT OF BLOOD PRESSURE IN PATIENTS WITH ACUTE AORTIC DISSECTION. Masaki Okajima, Yuko Nakayama, Hiroki Sano, Akihide Kurita, Takashi Fujita, Koji Sato, Yoshinao Koshida, Tsuyoshi Yoshimuta, Toru Noda, Takumi Taniguchi. J Hypertens. 30 e149 2012
  •  Efficacy of endotoxin adsorption therapy (polymyxin B hemoperfusion) for methicillin-resistant Staphylococcus aureus toxic shock syndrome: a case report about five patients. Taniguchi T, Sato K, Kurita A, Noda T, Okajima M Minerva Anestesiol. 79 7 758-61 2013
  •  Effect of organizational structure of the ICU on the prognosis: open format versus semi-closed format M Okajima, T Taniguchi. Crit Care 17 2 2013
  •  Attitudes toward automated external defibrillator use in Japan in 2011 Taniguchi T, Sato K, Kurita A, Noda T, Okajima M J Anesth. 28 1 34-7 2014
  •  Olprinone, phosphodiesterase III inhibitor, is useful for patients with severe acute heart failure due to takotsubo cardiomyopathy accompanied by subarachnoid hemorrhage. Masaki Okajima, Yoshinao Koshida, Toru Noda Takumi Taniguchi. Acute Med Surgery.  1 115-118. 2014
  •  Efficacy of continuous plasma diafiltration therapy in critical patients with acute liver failure Komura T, Taniguchi T, Sakai Y, Yamashita T, Mizukoshi E, Noda T, Okajima M, Kaneko S J Gastroenterol Hepatol. 29 4 782-6 2014

Conference Presentations

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「マウス心筋虚血再灌流障害および心筋梗塞モデルにおけるケミカルシャペロンの影響」(2009-) 
○「マウス心筋虚血再灌流障害および心筋梗塞モデルにおけるケミカルシャペロンの影響」(2008-)
○「ラット心筋虚血による梗塞巣へのサイトカイン吸着カラムを用いた血液浄化療法の効果」(2014-2016) 
○「ラット心筋虚血における梗塞巣へのサイトカイン吸着カラムを用いた血液浄化療法の効果」
○「ラット心筋虚血における梗塞巣へのサイトカイン吸着療法の有用性」

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

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