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Researcher Information

last modified:2020/04/10

Professor KIKUCHI Mitsuru


Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Medical Science, Graduate School of Medical Science
United Graduate School of Child Depelopment
School of Medicine, College of Medical, Pharmaceutical and Health Sciences


 TEL:076-265-2304 FAX:

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor 199906 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University 199403


Kanazawa University(2002/04/01-)

Year & Month of Birth


Academic Society

Japanese Society of Clinical Neurophysiology
The Japanese Society of Psychiatry and Neurology
The Japanese Society for Child and Adolescent Psychiatiry
Japanese Pharmarco-EEG Society


Japanese Pharmarco-EEG Society


Neurophysiology/General neuroscience、Psychiatric science

Speciality Keywords

Psychiatry, Neurophysiology

Research Themes

Neurophysiological study on schizophrenia

I explain the pathophysiology of schizophrenia using brain waves and other methods. Specifically, I focus on searching for physiological indications that could be useful for early judgment of treatment effect.

Brain developmental study using MEG/NIRS integrated device

The NIRS that reflects brain blood flow and the MEG that captures neural activity are both noninvasive and child-friendly brain function examination methods. My research is aimed at establishing new indices for the relationship between nerves and blood vessels by integrating these instruments and new physiological indices for evaluating child cerebrum development.

Pathophysiology of anxiety disorders


  •  Koenig T, Wada Y, Higashima M, Koshino Y, Strik W, Dierks T. Native EEG and treatment effects in neuroleptic-naive schizophrenic patients: Time and frequency domain approaches. 2007
  •  Komuro R, Oka H, Kidani T, Hanaoka A, Koshino Y Relationship between anxiety and thyroid function in patien ts with panic disorder. 29 77-81 2005
  •  Wada Y, Koshino Y Sequential EEG analysis during intermittent photic stimulation in never medicated patients with schizophrenia. 34 201-206 2003
  •  Wada Y, Koshino Y, Nanbu Y, Hashimoto T Effect of normal aging upon interhemispheric EEG coherence: analysis during rest and photic stimulation. 31 170-174 2000
  •  Wada Y, Koshino Y, Nanbu Y, Hashimoto T Effects of scopolamine on interhemispheric EEG coherence in healthy subjects: analysis during rest and photic stimulation. 31  109-115 2000


  •  A review of the default mode network in aging and dementia based on molecular imaging. Ouchi Y, Kikuchi M. Rev Neurosci. 28 263-8 2012/02
  •  Oxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics. Hirosawa T, Kikuchi M, Higashida H, Okumura E, Ueno S, Shitamichi K, Yoshimura Y, Munesue T, Tsubokawa T, Haruta Y, Nakatani H, Hashimoto T, Minabe Y.  Scientific Reports 2 2012/04
  •  Language performance and auditory evoked fields in 2- to 5-year-old children. Yoshimura Y, Kikuchi M, Shitamichi K, Ueno S, Remijn GB, Haruta Y, Oi M, Munesue T, Tsubokawa T, Higashida H, Minabe Y. EUROPEAN JOURNAL OF NEUROSCIENCE 35 644-50 2012/02
  •  Algorithm for estimation of brain structural location from head surface shape in young children. Hayashi N, Kikuchi M, Sanada S, Minabe Y, Miyati T, Hachiman Y, Arishita T, Iida H, Matsui O. NEUROREPORT 28 299-303 2012/03
  •  Lateralized Theta Wave Connectivity and Language Performance in 2- to 5-Year-Old Children. Kikuchi M, Shitamichi K, Yoshimura Y, Ueno S, Remijn GB, Hirosawa T, Munesue T, Tsubokawa T, Haruta Y, Oi M, Higashida H, Minabe Y. JOURNAL OF NEUROSCIENCE 31 14984-14988 2011/10

show all

  •  Effects of brain amyloid deposition and reduced glucose metabolism on the default mode of brain function in normal aging.  Kikuchi M,Hirosawa T, Yokokura M, Yagi S, Mori N, Yoshikawa E, Yoshihara Y, Sugihara G, Takebayashi K, Iwata Y, Suzuki K, Nakamura K, Ueki T, Minabe Y, Ouchi Y.  JOURNAL OF NEUROSCIENCE 31 11193-9 2011/08
  •  Frontal areas contribute to reduced global coordination of resting-state gamma activities in drug-naïve patients with schizophrenia. Kikuchi M, Hashimoto T, Nagasawa T, Hirosawa T, Minabe Y, Yoshimura M, Strik W, Dierks T, Koenig T. SCHIZOPHRENIA RESEARCH 130 187-94 2011/08
  •  EEG microstate analysis in drug-naive patients with panic disorder. Kikuchi M, Koenig T, Munesue T, Hanaoka A, Strik W, Dierks T, Koshino Y, Minabe Y. PLoSOne 6 e22912 2011/06
  •  Reduced acetylcholinesterase activity in the fusiform gyrus in adults with autism spectrum disorders. Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Tsujii M, Futatsubashi M, Iwata Y, Tsuchiya KJ, Matsumoto K, Takebayashi K, Wakuda T, Yoshihara Y, Suda S, Kikuchi M, Takei N, Sugiyama T, Irie T, Mori N.  Arch Gen Psychiatry 68 306-13 2011/03
  •  CD38 and its role in oxytocin secretion and social behavior.  Higashida H, Yokoyama S, Kikuchi M, Munesue T. Horm Behav. 2011/12
  •  Hemodynamic responses to visual stimuli in cortex of adults and 3- to 4-year-old children. Remijn GB, Kikuchi M, Yoshimura Y, Shitamichi K, Ueno S, Nagao K, Munesue T, Kojima H, Minabe Y.  Brain Res. 6 242-51 2011/04

Conference Presentations

Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research


Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

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