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Researcher Information

last modified:2019/02/15

Associate Professor BABA Tomohisa

Mail

Faculty, Affiliation

Cancer Research Institute

College and School Educational Field

Division of Cancer Medicine, Graduate School of Medical Science

Laboratory

Molecular Bioregulation TEL:076-265-2768 FAX:076-234-4520

Academic Background

【Academic background(Doctoral/Master's Degree)】
Hokkaido University Doctor 200603 Completed
【Degree】
Doctor of philosophy

Career

postdoctoral fellow(2006/04/01-2007/03/31)
Assistant Professor Cancer Research Institute(2007/04/01-)

Year & Month of Birth

1977/05

Academic Society

Japanese Society for Immunology
Japanese Cancer Association

Award

Specialities

Immunology

Speciality Keywords

immunotolerance

Research Themes

Mechanism of induction of central tolerance by thymic dendritic cells

Books

Papers

  •  MIP-1alpha/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia Journal of Experimental Medicine 210 12 2661 2013/11
  •  Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpα+ dendritic cells: a murine model. Baba T,Badr Mel S,Tomaru U,Ishizu A,Mukaida N PLoS One 7 7 e41154 2012/07
  •  Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner. Baba T,Nakamoto Y,Mukaida N J Immunol 183 5 3053-63 2009/09
  •  Rat CD4+ CD8+ macrophages kill tumor cells through an NKG2D- and granzyme/perforin-dependent mechanism Tomohisa Baba, Sari Iwasaki, Akihiro Ishizu The journal of immunology 180 2999-3006 2008/03
  •  CD4+/CD8+ macrophages infiltrating at inflammatory sites: a population of monocytes/macrophages with a cytotoxic phenotype Baba Tomohisa, Ishizu Akihiro, Iwasaki Sari Blood 107 2004-2012 2006/03

show all

  •  Chronic graft-versus-host disease-like autoimmune disorders spontaneously occurred in rats with neonatal thymus atrophy Baba Tomohisa, Ishizu Akihiro, Yoshiki Takashi Eur J Immunol 35 1731-1740 2005/05
  •  Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice. Kostadinova FI,Baba T,Ishida Y,Kondo T,Popivanova BK,Mukaida N J Leukoc Biol 88 1 133-43 2010/07

Conference Presentations

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「CD4+CD8+マクロファージの抗腫瘍メカニズムと免疫学的役割に関する研究」(2007-2008) 
○「胸腺Sirpα+樹状細胞の機能的特徴と自己免疫寛容における役割の解明」(2009-) 
○「胸腺Sirpα+樹状細胞による自己免疫寛容の新規誘導メカニズムの解明」(2011-2012) 
○「胸腺Sirpα+樹状細胞の機能的特徴と自己免疫寛容における役割の解明」(2009-2010) 
○「慢性骨髄性白血病発症における正常骨髄細胞との相互作用機構の解明」(2013-2015) 

Classes (Bachelors)

Classes (Graduate Schools)

○Seminars on Cytokines(2017)
○Seminars on Cytokines(2017)
○Seminar on Tumor Biology(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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