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Researcher Information

last modified：2023/03/27

Professor　TAKAMURA Masayuki

Mail Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences　Department of Cardiovascular Medicine
Professor

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Graduate School of Medical Science
Graduate School of Advanced Preventive Medical Sciences
Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of Cardiovascular Medicine　TEL:076-265-2259　FAX:076-234-4210

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University　Doctor　Graduate School, Division of Medical Sciences　Internal Medicine　199803　Completed
【Academic background(Bachelor's Degree)】
Kanazawa University　Medical science　199303

Career

Year & Month of Birth

1967/04

Academic Society

Japanese Circulation Society
Japanese Circulation Society
Japanaese Society of Internal Medicine
Japanese Society of Imaging and Dynamics
Japanese Society for Regenarative Medicine
Japanese Heart Rhythm Society
Japanese Heart Failure Society
Japanese Coronary Association

Award

Specialities

Heart failure、General internal medicine (including psychosomatic medicine)

Speciality Keywords

Ischemia reperfusion, Myocardial regenaration, Angiogenesis, Endotherin, Clinical electorophysiology

Research Themes

Coronary circulation physiology (explanation of mechanism of myocardial ischemia reflux disorder and its treatment, examination of endothelin coronary circulation and its roles in ischemic condition)

Myocardial regeneration after ischemia reperfusion injury

Books

  • 　HAMAOKA TAKUTO, TAKAMURA MASAYUKI　CURRENT THERAPY IN CARDIOVASCULAR DISEASES　2022

Papers

  • 　Diabetes impairs the angiogenic capacity of human adipose-derived stem cells by reducing the CD271+ subpopulation in adipose tissue. 　Inoue O, Usui S, Takashima SI, Nomura A, Yamaguchi K, Takeda Y, Goten C, Hamaoka T, Ootsuji H, Murai H, Kaneko S, Takamura M. 　Biochem Biophys Res Commun.　517　2　369-375　2019/07/27
  • 　Adipose tissue-derived stem cells as a regenerative therapy for a murine steatohepatitis-induced cirrhosis model.　HEPATOLOGY　2013/05
  • 　Effect of pioglitazone on muscle sympathetic nerve activity in type 2 diabetes mellitus with α-glucosidase inhibitor　Kobayashi D, Takamura M, Murai H, Usui S, Ikeda T, Inomata J, Takashima S, Kato T, Furusho H, Takeshita Y, Ota T, Takamura T, Kaneko S.　AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL　158　2　86‐91　2010/12
  • 　S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.　Ohkura S, Takashima S, Usui S, Kaneko S, Takuwa Y, Takamura M et al　CARDIOVASCULAR RESEARCH　Epub　2009/09
  • 　Altered firing pattern of single-unit muscle sympathetic nerve activity during handgrip exercise in chronic heart failure.　JOURNAL OF PHYCOLOGY　587　11, 2613-22　2009/06

show all

  • 　Current status of anticoagulation therapy for elderly atrial fibrillation patients in Japan.　JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION　72　12　 2058-61　2008/12
  • 　The attitudes of Japanese high school students toward cardiopulmonary resuscitation.　Taniguchi Takumi, Okajima Masaki, Takamura Masayuki, Kaneko Shuichi et al　RESUSCITATION　78　3　 340-345　2008/09
  • 　G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.　Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M et al　CARDIOVASCULAR RESEARCH　79　4　 689-697　2008/09
  • 　AGEs-RAGE System Mediates Atrial Structural Remodeling in Diabetic Rat　Yamashita Takeshi, Sekiguchi Akiko, Tsuneda Takayuki, Takamura Masayuki et al　JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY　19　4　 415-420　2008/04
  • 　Altered interaction between plasminogen activator inhibitor type 1 activity and sympathetic nerve activity with aging.　JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION　72　 458 - 462　2008/06
  • 　What are arrhythmogenic substrates in diabetic rat atria?　Yamashita T, Sekiguchi A, Sagara K, Takamura M et al　JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY　17　8　 890-894　2006/08
  • 　Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway.　Minamino T, Nishi J, Tateno K, Oyama T, KatsunoT, Miyauchi H, Orimo M, Okada S, Takamura M et al　CIRCULATION　29　114(9)　 953-960　2006/09
  • 　The Rho/Rho-kinase System Are Involved in Rapid Pacing-induced Changes of Atrial Refractory Period in a Canine Model.　Sakagami S, Takamura M et al　Journal of arrythmia　22　 267-273　2006/02
  • 　Effect of pimobendan on cardiopulmonary baroreflex control of sympathetic nerve activity in healthy young men.　Autonervus Neuroscience　122　 100-106　2005/10
  • 　The Activity of Single Muscle Sympathetic Vasoconstrictor Nerve Unit is Affected by Physiologic Stress in Humans.　Takata S, Maruyama M, Nakano M, Kobayashi D, Otowa K, Takamura M et al　AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY　290　2　 H853-860　2006/02
  • 　Tissue Doppler Analysis of Atrial Electromechanical Coupling in Paroxysmal Atrial Fibrillation.　Nagai Hideo, Takamura Masayuki et al　JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY　18　1　 39-44　2005/01
  • 　Beta-Adrenergic receptor blockade impairs NO-dependent dilation of large coronary arteries during exercise.　AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY　284　 H501-H510　2003/02
  • 　Enhanced contribution of NO to exercise-induced coronary responses after alpha-adrenergic receptor blockade.　AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY　282　 H508-H515　2002/02
  • 　Influence of dual ETA/ETB-receptor blockade on coronary responses to treadmill exercise in dogs.　JOURNAL OF APPLIED PHYSIOLOGY　89　 2041-2048　2000/11
  • 　Detection of the earliest ventricular contraction site in patients with Wolff-Parkinson-White syndrome using two-dimensional guided M-mode tissue Doppler echocardiography　Takata S, Sakagami S, Furusho H, Takamura M et al　CARDIOLOGY　92　3　 189-195　1999/10
  • 　Two-dimensional guided M-mode color tissue Doppler echocardiography in artificial preexcitation models.　Takata S, Sakagami S, Furusho H, Takamura M et al　JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY　12　7　 582-289　1999/07
  • 　Bilateral coronary artery fistulas with multiple sites of drainage　Takata S, Sakagami S, Furusho H, Takamura M et al　JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION　62　10　 783-784　1998/10
  • 　Images in cardiovascular medicine. Three-dimensional computed tomography of corrected transposition of the great arteries.　Nagai Hideo, Takamura Masayuki et al　CIRCULATION　2/96　11　 4115　1997/12
  • 　Advantage of recording single-unit muscle sympathetic nerve activity in heart failure.　　3　109　2013/05
  • 　Augmented single-unit muscle sympathetic nerve activity in heart failure with chronic atrial fibrillation.　　JOURNAL OF PHYCOLOGY　1　590　509-518　2011/12
  • 　Severity Indices for Obstructive Sleep Apnea Syndrome Reflecting Glycemic Control or Insulin Resistance. 　Isobe Y, Nakatsumi Y, Sugiyama Y, Hamaoka T, Murai H, Takamura M, Kaneko S, Takada S, Takamura T.　Intern Med.　2019/07/22
  • 　The First Report of Purulent Pericarditis Associated with Aortic Stent-graft Infection Caused by Methicillin-susceptible Staphylococcus aureus.　Yamagami K, Tanaka Y, Tada H, Fujii H, Takamura M, Kawashiri MA. 　Intern Med.　2019/07/10
  • 　Insights From 10-Year Outcomes of Mesenchymal Stem Cell Transplantation in Heart Failure Patients. 　Inoue O, Takamura M.　Circ J.　83　7　1446-1448　2019/05/30
  • 　Rare and Deleterious Mutations in ABCG5/ABCG8 Genes Contribute to Mimicking and Worsening of Familial Hypercholesterolemia Phenotype. 　Tada H, Okada H, Nomura A, Yashiro S, Nohara A, Ishigaki Y, Takamura M, Kawashiri MA. 　Circ J.　83　9　1917-1924　2019/08/23
  • 　Clinical Impact of Carotid Plaque Score rather than Carotid Intima-Media Thickness on Recurrence of Atherosclerotic Cardiovascular Disease Events. 　Tada H, Nakagawa T, Okada H, Nakahashi T, Mori M, Sakata K, Nohara A, Takamura M, Kawashiri MA.　J Atheroscler Thromb.　2019/05/18
  • 　Lipoprotein(a) as an Old and New Causal Risk Factor of Atherosclerotic Cardiovascular Disease.　Tada H, Takamura M, Kawashiri MA.　J Atheroscler Thromb. 　2019/04/30
  • 　Quick sepsis-related organ failure assessment score as a possible predictor for in-hospital adverse events in infective endocarditis.　Tamura Y, Nomura A, Yoshida S, Tada H, Sakata K, Iino K, Furusho H, Takamura M, Takemura H, Yamagishi M, Kawashiri MA.　Acute Med Surg.　6　2　138-144　2019/04/01
  • 　Significant Association Between Coronary Artery Low-Attenuation Plaque Volume and Apnea-Hypopnea Index, But Not Muscle Sympathetic Nerve Activity, in Patients With Obstructive Sleep Apnea Syndrome.　Hamaoka T, Murai H, Kaneko S, Usui S, Inoue O, Sugimoto H, Mukai Y, Okabe Y, Tokuhisa H, Takashima S, Kato T, Furusho H, Kashiwaya S, Sugiyama Y, Nakatsumi Y, Takata S, Takamura M. 　Circ J　2018/09/07
  • 　Endogenous muscle atrophy F-box is involved in the development of cardiac rupture after myocardial infarction.　Usui S, Chikata A, Takatori O, Takashima SI, Inoue O, Kato T, Murai H, Furusho H, Nomura A, Zablocki D, Kaneko S, Sadoshima J, Takamura M.　J Mol Cell Cardiol　126　1-12　2018/11/06
  • 　Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation.　Tsuda T, Hayashi K, Fujino N, Konno T, Tada H, Nomura A, Tanaka Y, Sakata K, Furusho H, Takamura M, Kawashiri MA, Yamagishi M　Heart Rhythm.　16　6　829-837　2018/11/29
  • 　Characteristics of synthesized right-sided chest electrocardiograms in patients with acute pulmonary embolism.　Kusayama T, Furusho H, Kinoshita M, Kaneko S, Usuda K, Takamura M.　J Cardiol　73　4　313-317　2018/12/26
  • 　Impact of decreased ankle-brachial index on 30-day bleeding complications and long-term mortality in patients with acute coronary syndrome after percutaneous coronary intervention.　Nakahashi T, Tada H, Sakata K, Yakuta Y, Tanaka Y, Gamou T, Nomura A, Terai H, Horita Y, Ikeda M, Namura M, Takamura M, Hayashi K, Yamagishi M, Kawashiri MA.　J Cardiol.　74　2　116-122　2019/02/01
  • 　Sphigosine-1-phosphate receptor 1 promotes neointimal hyperplasia in a mouse model of carotid artery injury.　Kitano T, Usui S, Takashima SI, Inoue O, Goten C, Nomura A, Yoshioka K, Okajima M, Kaneko S, Takuwa Y, Takamura M.　Biochem Biophys Res Commun.　511　1　179-184　2019/02/15
  • 　Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.　Yamato M, Sakai Y, Mochida H, Kawaguchi K, Takamura M, Usui S, Seki A, Mizukoshi E, Yamashita T, Yamashita T, Ishida K, Nasti A, Tuyen HTB, Komura T, Yoshida K, Wada T, Honda M, Kaneko S.　　J Gastroenterol Hepatol.　2019/03/03
  • 　Coronary sinus catheter placement via left cubital vein for phrenic nerve stimulation during pulmonary vein isolation.　　Chikata A, Kato T, Usuda K, Fujita S, Maruyama M, Otowa KI, Takashima SI, Murai H, Usui S, Furusho H, Kaneko S, Takamura M.　Heart Vessels.　2019/04/10
  • 　Additive Prognostic Value of Carotid Plaque Score to Enhance the Age, Creatinine, and Ejection Fraction Score in Patients with Acute Coronary Syndrome.　Nakahashi T, Tada H, Sakata K, Nomura A, Ohira M, Mori M, Takamura M, Hayashi K, Yamagishi M, Kawashiri MA.　J Atheroscler Thromb.　2018
  • 　Effects of mineralocorticoid receptor antagonists on responses to hemorrhagic shock in rats.　Yamamoto K, Yamamoto T, Takamura M, Usui S, Murai H, Kaneko S, Taniguchi T　 World J Crit Care Med　7　1　1-8　2018
  • 　Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice.　Chadani H, Usui S, Inoue O, Kusayama T, Takashima SI, Kato T, Murai H, Furusho H, Nomura A, Misu H, Takamura T, Kaneko S, Takamura M　Int J Mol Sci　19　3　e878　2018
  • 　Impact of left atrial size on isolation area in the acute phase of pulmonary vein isolation using 28 mm cryoballoon.　Chikata A, Kato T, Usuda K, Fujita S, Maruyama M, Nagata Y, Sakagami S, Kanamori N, Yaegashi T, Saeki T, Kusayama T, Usui S, Furusho H, Kaneko S, Takamura M.　Pacing Clin Electrophysiol　2018
  • 　Significant correlation between renal 123I-metaiodobenzylguanidine scintigraphy and muscle sympathetic nerve activity in patients with primary hypertension　Takamura M, Murai H, Okabe Y, Okuyama Y, Hamaoka T, Mukai Y, Tokuhisa H, Inoue O, Takashima SI, Kato T, Matsuo S, Usui S, Furusho H, Kaneko S.　J Nucl Cardiol　24　2　363-371　2017/04/24
  • 　Long-Term Administration of Eicosapentaenoic Acid Improves Post-Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization.　Takamura M, Kurokawa K, Ootsuji H, Inoue O, Okada H, Nomura A, Kaneko S, Usui S.　J Am Heart Assoc.　6　2　2017/02/21
  • 　General anesthesia improves contact force and reduces gap formation in pulmonary vein isolation: a comparison with conscious sedation.　Chikata A, Kato T, Yaegashi T, Sakagami S, Kato C, Saeki T, Kawai K, Takashima SI, Murai H, Usui S, Furusho H, Kaneko S, Takamura M.　Heart Vessels.　2017/05/04
  • 　Impact of T wave amplitude in lead aVR on predicting cardiac events in ischemic and nonischemic cardiomyopathy patients with an implantable cardioverter defibrillator.　Tanaka Y, Konno T, Tamura Y, Tsuda T, Furusho H, Takamura M, Sakata K, Yamagishi M, Hayashi K.　Ann Noninvasive Electrocardiol.　2017/04/25
  • 　β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice.　Pongkan W, Takatori O, Ni Y, Xu L, Nagata N, Chattipakorn SC, Usui S, Kaneko S, Takamura M, Sugiura M, Chattipakorn N, Ota T.　 Mol Nutr Food Res.　2017/05/20
  • 　The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells.　Nasti A, Sakai Y, Seki A, Buffa GB, Komura T, Mochida H, Yamato M, Yoshida K, Ho TTB, Takamura M, Usui S, Wada T, Honda M, Kaneko S　Eur J Immunol　47　12　2163-2174　2017/12/01
  • 　Paradoxical impact of decreased low-density lipoprotein cholesterol level at baseline on the long-term prognosis in patients with acute coronary syndrome.　Nakahashi T, Tada H, Sakata K, Yakuta Y, Tanaka Y, Nomura A, Gamou T, Terai H, Horita Y, Ikeda M, Namura M, Takamura M, Hayashi K, Yamagishi M, Kawashiri MA　Heart Vessels.　2017/12/29
  • 　Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.　Ohkura SI, Usui S, Takashima SI, Takuwa N, Yoshioka K, Okamoto Y, Inagaki Y, Sugimoto N, Kitano T, Takamura M, Wada T, Kaneko S, Takuwa Y　PLoS One　12　8　e0182329　2017/08/03
  • 　Ability of the prognostic model of J-ACCESS study to predict cardiac events in a clinical setting: The APPROACH study.　Aburadani I, Usuda K, Sumiya H, Sakagami S, Kiyokawa H, Matsuo S, Takamura M, Murai H, Takashima S, Kitano T, Okuda K, Nakajima K.　J Cardiol.　2018/01/06
  • 　Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits.　Saito Y, Misu H, Takayama H, Takashima SI, Usui S, Takamura M, Kaneko S, Takamura T, Noguchi N.　Biol Pharm Bull.　41　5　828-832　2018
  • 　Evaluation of the risk factors for ventricular arrhythmias secondary to QT prolongation induced by papaverine injection during coronary flow reserve studies using a 4 Fr angio-catheter.　Okabe Y, Otowa K, Mitamura Y, Murai H, Usui S, Kaneko S, Takamura M　Heart Vessels.　2018/04/30
  • 　Occult constrictive pericardial disease emerging 40 years after chest radiation therapy: a case report. 　Goten C, Murai H, Takashima SI, Kato T, Usui S, Furusho H, Saeki T, Sakagami S, Takemura H, Kaneko S, Takamura M.　BMC Cardiovasc Disord. 　18　1　107　2018/05/31
  • 　Optimal Lesion Size Index to Prevent Conduction Gap during Pulmonary Vein Isolation. 　Kanamori N, Kato T, Sakagami S, Saeki T, Kato C, Kawai K, Chikata A, Takashima SI, Murai H, Usui S, Furusho H, Kaneko S, Takamura M.　J Cardiovasc Electrophysiol.　2018/09/03
  • 　Differential effects of lipophilic and hydrophilic statins on muscle sympathetic nerve activity in heart failure with preserved left ventricular ejection fraction. 　Tokuhisa H, Murai H, Okabe Y, Hamaoka T, Sugimoto H, Mukai Y, Inoue O, Takashima SI, Kato T, Usui S, Furusho H, Kaneko S, Takamura M.　Auton Neurosci.　213　8-14　2018/09/02
  • 　Silent Aspiration of Esophageal Cooling Solution During Pulmonary Vein Isolation Using Hot Balloon. 　Chikata A, Kato T, Usuda K, Takamura M. 　Circ J　2019/08/10
  • 　Optimization of the hot balloon ablation strategy using real-time pulmonary vein potential monitoring. 　Chikata A, Kato T, Usuda K, Fujita S, Takaoka M, Tsuda T, Hayashi K, Furusho H, Takamura M.　J Cardiovasc Electrophysiol.　2019/12/11
  • 　Silent Aspiration of Esophageal Cooling Solution During Pulmonary Vein Isolation Using Hot Balloon.　Akio Chikata,Takeshi Kato,Kazuo Usuda,Masayuki Takamura　Circulation journal : official journal of the Japanese Circulation Society　83　12　2568　2019/11/25
  • 　Fasting and Non-Fasting Triglycerides and Risk of Cardiovascular Events in Diabetic Patients Under Statin Therapy.　Hayato Tada,Akihiro Nomura,Kenichi Yoshimura,Hiroshi Itoh,Issei Komuro,Masakazu Yamagishi,Masayuki Takamura,Masa-Aki Kawashiri　Circulation journal : official journal of the Japanese Circulation Society　84　3　509　2020/02/25
  • 　Beneficial effect of ezetimibe-atorvastatin combination therapy in patients with a mutation in ABCG5 or ABCG8 gene.　Hayato Tada,Hirofumi Okada,Akihiro Nomura,Masayuki Takamura,Masa-Aki Kawashiri　Lipids in health and disease　19　1　3　2020/01/04
  • 　Optimization of the hot balloon ablation strategy using real-time pulmonary vein potential monitoring.　Akio Chikata,Takeshi Kato,Kazuo Usuda,Shuhei Fujita,Motoki Takaoka,Toyonobu Tsuda,Kenshi Hayashi,Hiroshi Furusho,Masayuki Takamura　Journal of cardiovascular electrophysiology　31　1　163　2020/01
  • 　Severity Indices for Obstructive Sleep Apnea Syndrome Reflecting Glycemic Control or Insulin Resistance.　Yuki Isobe,Yasuto Nakatsumi,Yu Sugiyama,Takuto Hamaoka,Hisayoshi Murai,Masayuki Takamura,Shuichi Kaneko,Shigeo Takata,Toshinari Takamura　Internal medicine (Tokyo, Japan)　58　22　3227　2019/11/15
  • 　Quick sepsis-related organ failure assessment score as a possible predictor for in-hospital adverse events in infective endocarditis.　Yudai Tamura,Akihiro Nomura,Shohei Yoshida,Hayato Tada,Kenji Sakata,Kenji Iino,Hiroshi Furusho,Masayuki Takamura,Hirofumi Takemura,Masakazu Yamagishi,Masa-Aki Kawashiri　Acute medicine & surgery　6　2　138　2019/04
  • 　Sphigosine-1-phosphate receptor 1 promotes neointimal hyperplasia in a mouse model of carotid artery injury.　Teppei Kitano,Soichiro Usui,Shin-Ichiro Takashima,Oto Inoue,Chiaki Goten,Ayano Nomura,Kazuaki Yoshioka,Masaki Okajima,Shuichi Kaneko,Yoh Takuwa,Masayuki Takamura　Biochemical and biophysical research communications　511　1　179　2019/03/26
  • 　Impact of decreased ankle-brachial index on 30-day bleeding complications and long-term mortality in patients with acute coronary syndrome after percutaneous coronary intervention.　Takuya Nakahashi,Hayato Tada,Kenji Sakata,Yohei Yakuta,Yoshihiro Tanaka,Tadatsugu Gamou,Akihiro Nomura,Hidenobu Terai,Yuki Horita,Masatoshi Ikeda,Masanobu Namura,Masayuki Takamura,Kenshi Hayashi,Masakazu Yamagishi,Masa-Aki Kawashiri　Journal of cardiology　74　2　116　2019/08
  • 　Genomics of hypertriglyceridemia.　Hayato Tada,Masayuki Takamura,Masa-Aki Kawashiri　Advances in clinical chemistry　97　141　2020
  • 　Lipoprotein (a) and the Risk of Chronic Kidney Disease in Hospitalized Japanese Patients.　Hayato Tada,Kan Yamagami,Tetsuo Nishikawa,Taiji Yoshida,Ryota Teramoto,Kenji Sakata,Masayuki Takamura,Masa-Aki Kawashiri　Internal medicine (Tokyo, Japan)　59　14　1705　2020
  • 　Antegrade Balloon Aortic Valvuloplasty for the Highly Frail Patient of Severe Aortic Stenosis Complicated with Transthyretin-type Cardiac Amyloidosis.　Shohei Yoshida,Hayato Tada,Tetsuo Nishikawa,Tamami Nakagawa-Kamiya,Takuya Nakahashi,Kenji Sakai,Kenji Sakata,Masa-Aki Kawashiri,Masahito Yamada,Masayuki Takamura　Internal medicine (Tokyo, Japan)　59　8　1053　2019/12/26
  • 　The First Report of Purulent Pericarditis Associated with Aortic Stent-graft Infection Caused by Methicillin-susceptible Staphylococcus aureus.　Kan Yamagami,Yoshihiro Tanaka,Hayato Tada,Hiroshi Fujii,Masayuki Takamura,Masa-Aki Kawashiri　Internal medicine (Tokyo, Japan)　58　21　3103　2019/11/01
  • 　Coronary sinus catheter placement via left cubital vein for phrenic nerve stimulation during pulmonary vein isolation.　Akio Chikata,Takeshi Kato,Kazuo Usuda,Shuhei Fujita,Michiro Maruyama,Kan-Ichi Otowa,Shin-Ichiro Takashima,Hisayoshi Murai,Soichiro Usui,Hiroshi Furusho,Shuichi Kaneko,Masayuki Takamura　Heart and vessels　34　10　1710　2019/10
  • 　Diabetes impairs the angiogenic capacity of human adipose-derived stem cells by reducing the CD271+ subpopulation in adipose tissue.　Oto Inoue,Soichiro Usui,Shin-Ichiro Takashima,Ayano Nomura,Kosei Yamaguchi,Yusuke Takeda,Chiaki Goten,Takuto Hamaoka,Hiroshi Ootsuji,Hisayoshi Murai,Shuichi Kaneko,Masayuki Takamura　Biochemical and biophysical research communications　517　2　369　2019/09/17
  • 　Rare and Deleterious Mutations in ABCG5/ABCG8 Genes Contribute to Mimicking and Worsening of Familial Hypercholesterolemia Phenotype.　Hayato Tada,Hirofumi Okada,Akihiro Nomura,Satoshi Yashiro,Atsushi Nohara,Yasushi Ishigaki,Masayuki Takamura,Masa-Aki Kawashiri　Circulation journal : official journal of the Japanese Circulation Society　83　9　1917　2019/08/23
  • 　Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.　Masatoshi Yamato,Yoshio Sakai,Hatsune Mochida,Kazunori Kawaguchi,Masayuki Takamura,Soichiro Usui,Akihiro Seki,Eishiro Mizukoshi,Taro Yamashita,Tatsuya Yamashita,Kousuke Ishida,Alessandro Nasti,Ho Thuy Bich Tuyen,Takuya Komura,Keiko Yoshida,Takashi Wada,Masao Honda,Shuichi Kaneko　Journal of gastroenterology and hepatology　34　8　1432　2019/08
  • 　Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation.　Toyonobu Tsuda,Kenshi Hayashi,Noboru Fujino,Tetsuo Konno,Hayato Tada,Akihiro Nomura,Yoshihiro Tanaka,Kenji Sakata,Hiroshi Furusho,Masayuki Takamura,Masa-Aki Kawashiri,Masakazu Yamagishi　Heart rhythm　16　6　829　2019/06
  • 　Characteristics of synthesized right-sided chest electrocardiograms in patients with acute pulmonary embolism.　Takashi Kusayama,Hiroshi Furusho,Masaki Kinoshita,Shuichi Kaneko,Kazuo Usuda,Masayuki Takamura　Journal of cardiology　73　4　313　2019/04
  • 　Insights From 10-Year Outcomes of Mesenchymal Stem Cell Transplantation in Heart Failure Patients.　Oto Inoue,Masayuki Takamura　Circulation journal : official journal of the Japanese Circulation Society　83　7　1446　2019/06/25
  • 　Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial　Yoshio Sakai,Shinya Fukunishi,Masayuki Takamura,Oto Inoue,Shinichiro Takashima,Soichiro Usui,Akihiro Seki,Alessandro Nasti,Tuyen Thuy Bich Ho,Kazunori Kawaguchi,Akira Asai,Yusuke Tsuchimoto,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Yasuhito Imai,Kenichi Yoshimura,Toshinori Murayama,Takashi Wada,Kenichi Harada,Kazuhide Higuchi,Shuichi Kaneko　JMIR Research Protocols　9　3　e17904　2020/03/31
  • 　Takotsubo cardiomyopathy complicated by cardiac tamponade due to non-hemorrhagic pericardial effusion: a case report.　Yuta Nagamori,Takuto Hamaoka,Hisayoshi Murai,Shinichiro Takashima,Takeshi Kato,Soichiro Usui,Kenji Sakata,Hiroshi Furusho,Masaaki Kawashiri,Masayuki Takamura　BMC cardiovascular disorders　20　1　67　2020/02/06
  • 　Clinical Impact of Carotid Plaque Score rather than Carotid Intima-Media Thickness on Recurrence of Atherosclerotic Cardiovascular Disease Events.　Hayato Tada,Tamami Nakagawa,Hirofumi Okada,Takuya Nakahashi,Mika Mori,Kenji Sakata,Atsushi Nohara,Masayuki Takamura,Masa-Aki Kawashiri　Journal of atherosclerosis and thrombosis　27　1　38　2020/01/01
  • 　Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.　Kenshi Hayashi,Ryota Teramoto,Akihiro Nomura,Yoshihiro Asano,Manu Beerens,Yasutaka Kurata,Isao Kobayashi,Noboru Fujino,Hiroshi Furusho,Kenji Sakata,Kenji Onoue,David Y Chiang,Tuomas O Kiviniemi,Eva Buys,Patrick Sips,Micah L Burch,Yanbin Zhao,Amy E Kelly,Masanobu Namura,Yoshihito Kita,Taketsugu Tsuchiya,Bunji Kaku,Kotaro Oe,Yuko Takeda,Tetsuo Konno,Masaru Inoue,Takashi Fujita,Takeshi Kato,Akira Funada,Hayato Tada,Akihiko Hodatsu,Chiaki Nakanishi,Yuichiro Sakamoto,Toyonobu Tsuda,Yoji Nagata,Yoshihiro Tanaka,Hirofumi Okada,Keiich Usuda,Shihe Cui,Yoshihiko Saito,Calum A MacRae,Seiji Takashima,Masakazu Yamagishi,Masa-Aki Kawashiri,Masayuki Takamura　Cardiovascular research　116　13　2116　2020/01/24
  • 　A Healthy Family of Familial Hypobetalipoproteinemia Caused by a Protein-truncating Variant in the PCSK9 Gene.　Hayato Tada,Hirofumi Okada,Akihiro Nomura,Atsushi Nohara,Masayuki Takamura,Masa-Aki Kawashiri　Internal medicine (Tokyo, Japan)　59　6　783　2020
  • 　Lipoprotein(a) as an Old and New Causal Risk Factor of Atherosclerotic Cardiovascular Disease.　Hayato Tada,Masayuki Takamura,Masa-Aki Kawashiri　Journal of atherosclerosis and thrombosis　26　7　583　2019/07/01
  • 　Renal iodine123-metaiodobenzylguanidine scintigraphy relates to muscle sympathetic nervous activity in heart failure with reduced ejection fraction.　Yoshitaka Okabe,Hisayoshi Murai,Hideki Tokuhisa,Takuto Hamaoka,Yusuke Mukai,Hiroyuki Sugimoto,Shin-Ichiro Takashima,Takeshi Kato,Shinro Matsuo,Soichiro Usui,Hiroshi Furusho,Masayuki Takamura,Shuichi Kaneko　Autonomic neuroscience : basic & clinical　226　102671　2020/07
  • 　Transient swallowing-induced atrial tachycardia in a patient with genotyped hypertrophic cardiomyopathy.　Noboru Fujino,Kenshi Hayashi,Kenji Sakata,Hayato Tada,Chiaki Nakanishi,Toyonobu Tsuda,Akihiro Nomura,Shohei Yoshida,Yuichiro Sakamoto,Takeshi Kato,Hiroshi Furusho,Masa-Aki Kawashiri,Masayuki Takamura　Clinical case reports　8　9　1809　2020/09　
  • 　Hokuriku-plus familial hypercholesterolaemia registry study: rationale and study design.　Hayato Tada,Hirofumi Okada,Shohei Yoshida,Masaya Shimojima,Akihiro Nomura,Toyonobu Tsuda,Mika Mori,Shin-Ichiro Takashima,Takeshi Kato,Soichiro Usui,Kenji Sakata,Kenshi Hayashi,Noboru Fujino,Akihiro Inazu,Shizuko Takahara,Yasuhito Imai,Takao Matsubara,Atsushi Nohara,Kenji Miwa,Masanobu Namura,Hidenobu Terai,Taiji Yoshida,Tsutomu Araki,Masahiro Minamoto,Toru Aburao,Yuji Ito,Chiaki Nakanishi,Suguru Kawasaki,Yasuhiro Todo,Junji Koizumi,Yoshihito Kita,Hiroshi Matsumoto,Hiroaki Shintaku,Akihiko Hodatsu,Hidekazu Ino,Toshinori Higashikata,Mutsuko Takata,Katsushi Misawa,Masato Yamaguchi,Yoshihiro Noji,Kazuo Osato,Tomohito Mabuchi,Taro Ichise,Bunji Kaku,Shoji Katsuda,Manabu Fujimoto,Katsuharu Uchiyama,Kensuke Fujioka,Takuya Nakahashi,Tsuyoshi Nozue,Ichiro Michishita,Kazuo Usuda,Kanichi Otowa,Kazuyasu Okeie,Satoshi Hirota,Isao Aburadani,Keisuke Kurokawa,Osamu Takatori,Shunichiro Hondo,Hiroyuki Oda,Shigeo Takata,Hisayoshi Murai,Masaki Kinoshita,Hideo Nagai,Yoshiteru Sekiguchi,Satoru Sakagami,Wataru Omi,Chikara Fujita,Tatsuo Katsuki,Hiroshi Ootsuji,Atsushi Igarashi,Manabu Nakano,Seiichiro Okura,Koji Maeno,Yasuhito Mitamura,Naoki Sugimoto,Masakazu Yamamoto,Hironobu Akao,Kouji Kajinami,Masayuki Takamura,Masa-Aki Kawashiri　BMJ open　10　9　e038623　2020/09/10
  • 　A case with familial hypercholesterolemia complicated with severe systemic atherosclerosis intensively treated for more than 30 years.　Tetsuo Nishikawa,Hayato Tada,Tamami Nakagawa-Kamiya,Satoru Niwa,Shohei Yoshida,Mika Mori,Kenji Sakata,Atsushi Nohara,Toshinori Higashikata,Hiroki Kato,Kenji Ino,Hirofumi Takemura,Masayuki Takamura,Masa-Aki Kawashiri　Journal of cardiology cases　22　5　216　2020/11
  • 　Novel Players and a Target of Stem Cell Therapy for the Heart.　Oto Inoue,Kosei Yamaguchi,Masayuki Takamura　Circulation journal : official journal of the Japanese Circulation Society　84　8　1230　2020/07/22
  • 　Association of proteinuria with incident atrial fibrillation in the general Japanese population.　Yoshihiro Tanaka,Hayato Tada,Satoshi Hara,Kenshi Hayashi,Ravi B Patel,Tetsuo Nishikawa,Atsushi Hashiba,Masayuki Takamura,Philip Greenland,Masa-Aki Kawashiri　Journal of cardiology　77　1　100　2020/08/23
  • 　Targeted Panel Sequencing will Boost Detection of Genetic Backgrounds of Familial Hypercholesterolemia in the World's Most Populous Country.　Hayato Tada,Masayuki Takamura,Masa-Aki Kawashiri　Journal of atherosclerosis and thrombosis　27　12　1261　2020/08/15
  • 　Correlation between estimated balloon contact by computer-aided engineering analysis and lesion area by hot balloon ablation.　Akio Chikata,Takeshi Kato,Hiroaki Nakagoe,Kazuo Usuda,Masayuki Takamura　Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing　60　2　353　2020/09/10
  • 　Prolongation of QT interval after pulmonary vein isolation for paroxysmal atrial fibrillation.　Akio Chikata,Takeshi Kato,Kazuo Usuda,Shuhei Fujita,Michiro Maruyama,Kan-Ichi Otowa,Keisuke Usuda,Satoru Niwa,Toyonobu Tsuda,Kenshi Hayashi,Masayuki Takamura　Journal of cardiovascular electrophysiology　31　9　2371　2020/06/17　
  • 　Serum sitosterol level predicting ABCG5 or ABCG8 genetic mutations.　Nobuko Kojima,Hayato Tada,Soichiro Usui,Kenji Sakata,Kenshi Hayashi,Atsushi Nohara,Akihiro Inazu,Masayuki Takamura,Masa-Aki Kawashiri　Clinica chimica acta; international journal of clinical chemistry　507　11　2020/08
  • 　What is the mechanism of genetic contributions to the development of atherosclerosis?　Hayato Tada,Masayuki Takamura,Masa-Aki Kawashiri　Atherosclerosis　307　72　2020/08
  • 　Personalized medicine for cardiovascular diseases.　Hayato Tada,Noboru Fujino,Akihiro Nomura,Chiaki Nakanishi,Kenshi Hayashi,Masayuki Takamura,Masa-Aki Kawashiri　Journal of human genetics　66　1　67　2020/08/08　
  • 　Impact of concomitant peripheral artery disease on contrast-induced acute kidney injury and mortality in patients with acute coronary syndrome after percutaneous coronary intervention.　Takuya Nakahashi,Hayato Tada,Kenji Sakata,Yohei Yakuta,Taiji Yoshida,Yoshihiro Tanaka,Akihiro Nomura,Hidenobu Terai,Yuki Horita,Masatoshi Ikeda,Masanobu Namura,Masayuki Takamura,Masa-Aki Kawashiri　Heart and vessels　35　10　1360　2020/10
  • 　Different prognosis between severe and very severe obstructive sleep apnea patients; Five year outcomes.　Takuto Hamaoka,Hisayoshi Murai,Shigeo Takata,Tadayuki Hirai,Hiroyuki Sugimoto,Yusuke Mukai,Yoshitaka Okabe,Hideki Tokuhisa,Shin-Ichiro Takashima,Soichiro Usui,Kenji Sakata,Masa-Aki Kawashiri,Yu Sugiyama,Yasuto Nakatsumi,Masayuki Takamura　Journal of cardiology　76　6　573　2020/12
  • 　A case of pulmonary arterial hypertension with chronic hepatitis that resulted in hepatosplenomegaly after administration of prostaglandin I2.　Chiaki Goten,Soichiro Usui,Takuto Hamaoka,Tomoya Harada,Oto Inoue,Hirofumi Okada,Shin-Ichiro Takashima,Takeshi Kato,Hisayoshi Murai,Kenji Sakata,Hiroshi Furusho,Masa-Aki Kawashiri,Masayuki Takamura　Journal of cardiology cases　21　5　182　2020/05
  • 　Low-Density Lipoprotein Cholesterol Level cannot be too Low: Considerations from Clinical Trials, Human Genetics, and Biology.　Hayato Tada,Soichiro Usui,Kenji Sakata,Masayuki Takamura,Masa-Aki Kawashiri　Journal of atherosclerosis and thrombosis　27　6　489　2020/06/01
  • 　Prevalence, self-awareness, and LDL cholesterol levels among patients highly suspected as familial hypercholesterolemia in a Japanese community.　Hayato Tada,Junichi Shibayama,Tetsuo Nishikawa,Hirofumi Okada,Akihiro Nomura,Soichiro Usui,Kenji Sakata,Atsushi Hashiba,Akihiro Inazu,Masayuki Takamura,Masa-Aki Kawashiri　Practical laboratory medicine　22　e00181　2020/11
  • 　A reassessment of the Japanese clinical diagnostic criteria of familial hypercholesterolemia in a hospital-based cohort using comprehensive genetic analysis.　Hayato Tada,Hirofumi Okada,Akihiro Nomura,Atsushi Nohara,Soichiro Usui,Kenji Sakata,Masayuki Takamura,Masa-Aki Kawashiri　Practical laboratory medicine　22　e00180　2020/11

Conference Presentations

Others

  • 　Crosstalk Between Endothelin and Nitric Oxide in the Control of Vascular Tone.　6　4　 265-276　2001/12

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「脂肪組織を用いた心不全再生医療に重要なサイトカイン抑制型因子の同定」(2016-2018)　
○「脂肪組織由来間質細胞による心筋再生医療の作用機序に関する研究」(2013-2015)　
○「遺伝子解析を含む心筋虚血再還流障害に対するエンドセリン受容体拮抗薬の影響」(2005-2007)　
○「遺伝子解析を含む心筋虚血再還流障害に対するエンドセリン受容体拮抗薬の影響」(2004-2006)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Internal Medicine(BSL)(2019)
○Internal Medicine(BSL)(2019)
○Department of Cardiology(2018)
○Department of Cardiology(2018)
○regenerative medicine(2018)

Classes (Graduate Schools)

○Introduction to MedicineⅡ(2021)
○Internal Medicine(2021)
○Internal Medicine(2021)
○Introduction to MedicineⅠ(2021)
○Internal Medicine(2019)
○Introduction to Medicine(2019)
○Internal Medicine(2019)
○Cardiovascular Medicine(2018)
○system biology(2018)

International Project

International Students

Lecture themes

○Myocardial regenaration

Others (Social Activities)

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