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Researcher Information

last modified:2020/03/31

Associate Professor HIGASHI (ENDOH) HIROSHI

Mail Laboratory Website

Faculty, Affiliation

Faculty of Biological Science and Technology,Institute of Science and Engineering

College and School Educational Field

Division of Natural Sciences, Graduate School of Natural Science and Technology
Division of Natural System, Graduate School of Natural Science and Technology
Course in Biosystems, School of Biological Science and Technology, College of Science and Engineering


Laboratory of Genetics TEL:076-264-6232 FAX:076-264-6232

Academic Background

【Academic background(Doctoral/Master's Degree)】
Tohoku University Master 198103 Completed
Tohoku University Doctor 198403 Completed
【Academic background(Bachelor's Degree)】
Tohoku University 197903


Kanazawa University Liberal Arts and Science(1995/02/01-1996/03/31)
Kanazawa University Faculty of Science(1996/04/01-2004/03/31)
Kanazawa University Grad. Sch. of Natural Sci. Technol.(2004/04/01-)

Year & Month of Birth


Academic Society



Evolutionary biology、、Genetics Evolution Protozoa

Speciality Keywords

Evolutionary protistology, Parasitism, Differentiation of mitochondria

Research Themes

Cellulolysis by the protozoan Tetrahymena

Cellulolysis by the protozoan Tetrahymena

Evolution of dicyemid mesozoans and their strategy to parasitism

Molecular evolutionary strategies in protists

Life cycle of the dinoflagellates and their phylogenetic position

Nuclear apoptosis in Tetrahymena thermophila


  •  Evolution of Life: Fossils, Molecules and Culture Springer-Verlag 1991/01


  •  Abortive conjugation induced by UV-B at meiotic prophase in conjugation of Tetrahymena thermophila. DEVELOPMENTAL GENETICS 23 2 151-157 1998/04
  •  Binarry fission and encystation of Opalina sp. in axenic medium. ZOOLOGICAL SCIENCE 18 3 381-387 2001/04
  •  Novel aberrant nuclear behavior in abortive conjugation of tetrahymena thermophila: Joint selection of a meiotic product and macronucleus during nuclear selection. GENES & GENETIC SYSTEMS 74 1 29-32 1999/02
  •  A chimera theory on the origin of dicyemid mesozoans: Evolution driven by frequent lateral gene trnasfer from host to parasite T Noto, H Endoh BIOSYSTEMS 73 1 73-83 2004/01
  •  Developmentally regulated extrachromosomal circular DNA formation in the mesozoan Dicyema japonicum CHROMOSOMA 111 6 359-368 2003/03

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  •  Caspase-like activity in programmed nuclear death during conjugation of Tetrahymena thermophila CELL DEATH AND DIFFERENTIATION 10 634-640 2003/05
  •  Presence of a bacterial-like citrate synthase gene in Tetrahymena thermophila: Recent lateral gene transfers (LGT) or multiple gene losses subsequent to a single ancient LGT? A Mukai, H Endoh JOURNAL OF MOLECULAR EVOLUTION 58 5 540-549 2004/05
  •  Preferential cleavage of Paramecium DNA mediated by the C. elegans Tc1 transposase in vitro GENES & GENETIC SYSTEMS 78 6 391-398 2003/12
  •  Delayed degradation of parental macromuclear DNA in progarammed nuclear death of Paramecium caudatum GENESIS 40 1 15-21 2004/09
  •  Unusual distribution of mitochondrial large subunit rRNA in the cytosol during conjugation in Tetrahymena thermophila T Kobayashi, H Endoh GENES & GENETIC SYSTEMS 79 5 255-262 2004/10
  •  Reevaluation of the evolutionary position of opalinids based on 18S rDNA, and alpha- and beta-tubulin gene phylogenies A Nishi, K Ishida, H Endoh JOURNAL OF MOLECULAR EVOLUTION 60 6 695-705 2005/01
  •  Differentiation of somatic mitochondria and the structural changes in mtDNA during development of the dicyemid Dicyema japonicum (Mesozoa) H Awata, T Noto, H Endoh MOLECULAR GENETICS AND GENOMICS 273 6 441-449 2005/07
  •  A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila EUROPEAN JOURNAL OF BIOCHEMISTRY 272 20 5378-5387 2005/10
  •  Analysis of fruiting body development in the aggregative ciliate Sorogena stoianovitchae (Ciliophora, Colpodea) JOURNAL OF EUKARYOTIC MICROBIOLOGY 53 2 96-102 2006/03
  •  Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification N Kimura, K Mikami, N Nakamura, H Endoh PROTIST 157 3 303-314 2006/08
  •  New details from the complete life cycle of the red-tide dinoflagellate Noctiluca scintillans (Ehrenberg) McCartney Y Fukuda, H Endoh EUROPEAN JOURNAL OF PROTISTOLOGY 42 3 209-219 2006/09
  •  Peculiar behavior of distinct chromosomal DNA elements during and after development in the dicyemid mesozoan Dicyema japonicum H Awata, T Noto, H Endoh CHROMOSOME RESEARCH 14 8 817-830 2006/12
  •  Phylogenetic analyses of the dinoflagellate Noctiluca scintillans based on beta-tubulin and Hsp90 genes. Yasuhiro Fukuda EUROPEAN JOURNAL OF PROTISTOLOGY 43 1 1-7 2008/02
  •  Differentially expressed genes during fruiting body development in the aggregative ciliate Sorogena stoianovitchae (Ciliophora: Colpodea). Hiroki Sugimoto Journal of Eukaryotic Microbiology 55 2 10-16 2008/03
  •  Role of apoptosis-inducing factor (AIF) in programmed nuclear death during conjugation in Tetrahymena thermophila. Takahiko Akematsu BMC Cell Biology 11 13-27 2010/02
  •  Gigantic macroautophagy in programmed nuclear death of Tetrahymena thermophila. Takahiko Akemasu, Ronald E Pearlman Autophagy 6 7 901-911 2010/10
  •  Programmed nuclear death and its relation to apoptosis and autophagy during sexual reproduction in Tetrahymena thermophila Japanese Journal of Protozoology 45 1, 2 1-15 2012/04
  •  A protein-protein interaction in magnetosomes: TPR protein MamA interacts with an Mms6 protein Hoang Viet Nguyen, Emi Suzuki, Zachery Oestreicher, Hiroshi Minamide, Hiroshi Endoh, Yoshihiro Fukumori, Azuma Taoka Biochemistry and Biophysics Reports 7 39-44 2016/09
  •  A novel mitochondrial nuclease-associated protein: a major executor of the programmed nuclear death in Tetrahymena thermophila. Eriko Osada, Takahiko Akematsu, Tomoya Asano, Hiroshi Endoh BIOLOGY OF THE CELL 106 3 97-109 2014/04

Conference Presentations

Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research


Classes (Bachelors)

○Research Work in Biology(2)(2017)
○Genetics Lab(2017)
○Guide to Biology and Earth Sciences(2017)
○Microbiology 1(2017)
○Research Seminar in Biology (2)(2017)
○Research Seminar in Biology (1)(2017)
○Research Work in Biology(1)(2017)
○Basic Biology 2(2017)
○Experiments in Biology(2017)
○Experiments in Biology(2017)
○Experiments in Biology(2016)
○Genetics Lab(2016)
○Research Work in Biology(2)(2016)
○Research Seminar in Biology (1)(2016)
○Research Seminar in Biology (2)(2016)
○Genetics Lab(2016)
○Guide to Biology and Earth Sciences(2016)
○Microbiology 1(2016)
○Geo-biosphere and Human beings(2016)
○Geo-biosphere and Human beings(2016)
○Geo-biosphere and Human beings(2016)
○Geo-biosphere and Human beings(2016)
○Geo-biosphere and Human beings(2016)
○Geo-biosphere and Human beings(2016)
○Experiments in Biology(2016)
○Basic Biology 2(2016)
○Research Work in Biology(1)(2016)

Classes (Graduate Schools)

○Evolutionary Protistology(2017)
○Evolutionary Protistology(2017)
○Evolutionary Protistology(2017)
○Evolutionary Protistology(2017)
○Special Lecture on Systems Biology(2017)
○Genomic Systems Biology A(2017)
○Basic Systems Biology B(2016)
○Genomic Systems Biology A(2016)
○Evolutionary Protistology(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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