Jump to contents

Researcher Information

last modified:2017/05/23

Associate Professor KODERA Noriyuki

Mail Laboratory Website
Laboratory Website

Faculty, Affiliation

Bio-AFM Frontier Research Center  Imaging Research Division

College and School Educational Field

Division of Mathematical and Physical Science, Graduate School of Natural Science and Technology

Laboratory

Biophysics Laboratory

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Division of Basic Sciences 200509 Completed
Kanazawa University Master Division of Mathematical and Physical Sciences 200303 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University Department of Physics 200103
【Degree】
Doctor of Philosophy in Science

Career

Kanazawa University Bio-AFM FRC, Int. Sci. & Eng. Associate Professor(2011/08/01-)
Kanazawa University Bio-AFM FRC, Int. Sci. & Eng. Assistant Professor(2010/10/01-2011/07/31)
Kanazawa University Sch. Math. & Phys., Col. Sci. & Eng. Assistant Professor(2010/04/01-2010/09/30)
Japan Science and Technology Agency-CREST Postdoctoral Research Fellow(2007/04/01-2010/03/30)
Japan Society for the Promotion of Science Research Fellowship for Young Scientists (PD)(2005/10/01-2007/03/30)
Japan Society for the Promotion of Science Research Fellowship for Young Scientists (DC2)(2005/04/01-2005/09/30)

Year & Month of Birth

1978/10

Academic Society

The Biophysical Society of Japan
The Biophysical Society
The Japan Society of Applied Physics

Award

○The 9th Early Research in Biophysics Award(2013/10/29)
○Development Category, The Commendation for Science and Technology by the Minister of Educa(2013/04/16)
○Young Researcher’s Nanoprobe Technology Prize(2012/04/19)
○Uchida Prize Medal(2012/02/18)
○Best Paper Award of the Japan Society of Applied Physics(2007/07/06)
○Nikkei BP Technology Prize(2003/04/04)

Specialities

Biophyscis

Speciality Keywords

Motor proteins, Single-molecule measurements, Atomic force microscope

Research Themes

Development of high-speed atomic force microscopy and direct observation of structural dynamics of biomolecules

Development of high-speed atomic force microscopy and direct observation of structural dynamics of biomolecules We have developed and improved a high-speed atomic force microscope that allows us to simultaneously observe the structure and dynamics of biomolecules such as DNA, RNA and proteins. Using this new microscopy, we currently observe various biomolecules at work to understand their functional mechanisms. The left movie shows the walking behavior of myosin V, a vesicle transporter in cell, along actin filament (published in Nature, 2010). Please visit our lab website and enjoy watching other fantastic movies!

Direct observation of structural dynamics of biological molecules in action

Awards

Books

  •  Uchihashi, T., Kodera, N., Ando, T. Noncontact Atomic Force Microscopy Springer 2015
  •  Uchihashi, T., Kodera, N., Ando, T. Atomic Force Microscopy in Nanobiology Pan Stanford Publishing 2014
  •  Toshio Ando, N. Kodera Intrinsically Disordered Protein Analysis : Volume 2, Methods and Experimental Tools Humana Press 2012/07
  •  T. Ando, T. Uchihashi, N. Kodera, D. Yamamoto, M. Taniguchi, A. Miyagi, H. Yamashita Single Molecule Dynamics in Life Science Wiley-VCH 2008/12
  •  T. Ando, T. Uchihashi, N. Kodera, M. Shibata, D. Yamamoto, H. Yamashita Atomic force microscopy in liquid Wiley-VCH Verlag GmbH  2011/12

show all

  •  Takayuki Uchihashi, Noriyuki Kodera, Toshio Ando Single-molecule Studies of Proteins Springer New York 2013/01

Papers

  •  Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin Ngo, K. X., Umeki, N., Kijima, S. T., Kodera, N., Ueno, H., Furutani-Umezu, N., Nakajima, J., Noguchi, T. Q., Nagasaki, A., Tokuraku, K., Uyeda, T. Q. Scientific reports 6 35449 2016/10/20 
  •  CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation T. Davies, N. Kodera, GS. Kaminski Schierle, E. Rees, M. Erdelyi, CF. Kaminski, T. Ando, M. Mishima PLoS Biol. 13 e1002121 2015/04
  •  Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy KX. Ngo, N. Kodera, E. Katayama, T. Ando, TQ. Uyeda eLife 4 04806 2015/02
  •  High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils Watanabe-Nakayama, T., Itami, M., Kodera, N., Ando, T., Konno, H. Scientific Reports 6 28975 2016/07/04
  •  Two-ball structure of the flagellar hook-length control protein flik as revealed by high-speed atomic force microscopy N. Kodera, K. Uchida, T. Ando, S. Aizawa J. Mol. Biol. 427 2 406-414 2015/01/30 

show all

  •  The path to visualization of walking myosin V by high-speed atomic force microscopy N. Kodera, T. Ando Biophys. Rev. 6 42067 237-260 2014/01/01 
  •  IgGs are made for walking on bacterial and viral surfaces J. Preiner, N. Kodera, J. Tang, A. Ebner, M. Brameshuber, D. Blaas, N. Gelbmann, HJ. Gruber, T. Ando, P. Hinterdorfer Nature Communications 5 4394 2014/07
  •  High-Speed AFM and Applications to Biomolecular Systems T. Ando, T. Uchihashi, N Kodera Ann. Rev. Biophys. 42 1 393-414 2013/05
  •  Phosphorylation-Coupled Intramolecular Dynamics of Unstructured Regions in Chromatin Remodeler FACT M. Hashimoto, N. Kodera, Y. Tsunaka, M. Oda, M. Tanimoto, T. Ando, K. Morikawa, S. Tate Biophys. J. 104 10 2222-2234 2013/05
  •  Nano-scale alignment of proteins on a flexible DNA backbone Nojima, T. Konno, H. Kodera, N. Seio, K. Taguchi, H. Yoshida, M. PLoS One 7 12 e52534 2013/01
  •  High-Speed Atomic Force Microscopy Ando, T. Uchihashi, T. Kodera, N. Jpn. J. Appl. Phys. 51 8 2012/08
  •  Visualization of mobility by atomic force microscopy Ando, T. Kodera, N. Methods Mol Biol 896 2012/07
  •  Guide to video recording of structure dynamics and dynamic processes of proteins by high-speed atomic force microscopy Uchihashi, T. Kodera, N. Ando, T. Nature Protocols 7 6 1193-1206 2012/06
  •  Video imaging of walking myosin V by high-speed atomic force microscopy Kodera, N., Yamamoto, D., Ishikawa, R. & Ando, T. NATURE 468 72-76 2010/11
  •  Single-molecule imaging of photodegradation reaction in a chiral helical π-conjugated polymer chain Shinohara, K., Kodera, N. & Oohashi, T. J. Polym. Sci. Part A: Polym. Chem. 48 18 4103-4107 2010/09
  •  High-speed atomic force microscopy techniques for observing dynamic biomolecular processes Yamamoto, D., Uchihashi, T., Kodera, N., Yamashita, H., Nishikori, S., Ogura, T., Shibata, M. & Ando, T. Methods in Enzymol. 475 541-564 2010/07
  •  Contact-mode high-resolution high-speed atomic force microscopy movies of the purple membrane Casuso, I., Kodera, N., Le Grimellec, C., Ando, T. & Scheuring, S. Biophys J 97 5 1354-1361 2009/09
  •  Single-Molecule Imaging of a Micro-Brownian Motion of a Chiral Helical π-Conjugated Polymer as a Molecular Spring Driven by Thermal Fluctuations Shinohara, K., Kodera, N. & Ando, T. Chem. Lett. 38 7 690-691 2009/06
  •  Anisotropic diffusion of point defects in two-deimensional crystal of streptavidin observed by high-speed atomic force microscopy Yamamoto, D., Uchihashi, T., Kodera, N. & Ando, T. Nanotecnol. 19 38 384009 2008/09
  •  High resonance frequency force microscope scanner using inertia balance support Fukuma, T., Okazaki, Y., Kodera, N., Uchihashi, T. & Ando, T. Appl. Phys. Lett. 92 243119 2008/06
  •  High-speed AFM and nano-visualization of biomolecular processes Ando, T., Uchihashi, T., Kodera, N., Yamamoto, D., Miyagi, A., Taniguchi, M. & Yamashita, H. Pflugers Archiv Eur. J. Physiol. 456 1 211-225 2007/12
  •  Single molecular imaging of a micro-Brownian motion and a bond scission of a supramolecular chiral π-conjugated polymer as a molecular bearing driven by thermal fluctuations. Shinohara, K., Kodera, N. & Ando, T. Chem. Lett. 36 11 1378-1379 2007/10
  •  High-speed atomic force microscopy for observing dynamic biomolecular processes Ando, T., Uchihashi, T., Kodera, N., Yamamoto, D., Taniguchi, M., Miyagi, A. & Yamashita, H. J. Mol. Recognit. 20 448-458 2007/09
  •  Tip-sample distance control using photothermal actuation of a small cantilever for high-speed atomic force microscopy Yamashita, H., Kodera, N., Miyagi, A., Uchihashi, T., Yamamoto, D. & Ando, T. Rev. Sci. Instrum. 78 083702 2007/08
  •  Dynamic proportional-integral-differential controller for high-speed atomic force microscopy Kodera, N., Sakashita, M. & Ando, T. Rev. Sci. Instrum. 77 083704 2006/08
  •  Feed-forward compensation for high-speed atomic force microscopy imaging of biomolecules Uchihashi, T., Kodera, N., Itoh, H., Yamashita, H. & Ando, T. Jpn. J. Appl. Phys. 45 3B 1904-1908 2006/05
  •  High-speed atomic force microscopy for studying the dynamic behavior of protein molecules at work Ando, T., Uchihashi, T., Kodera, N., Miyagi, A., Nakakita, R., Yamashita, H. & Sakashita, M. Jpn. J. Appl. Phys. 45 3B 1897-1903 2006/03
  •  High-speed atomic force microscopy for capturing dynamic behavior of protein molecules at work Ando, T., Kodera, N., Uchihashi, T., Miyagi, A., Nakakita, R., Yamashita, H. & Matada, K. e-J. Surf. Sci. Nanotech. 3 384-392 2005/12
  •  Active damping of the scanner for high-speed atomic force microscopy Kodera, N., Yamashita, H. & Ando, T. Rev. Sci. Instrum. 76 053708 2005/04
  •  High-resolution imaging of myosin motor in action by a high-speed atomic force microscope Kodera, N., Kinoshita, T., Ito, T. & Ando, T. Adv. Exp. Med. Biol. 538 119-127 2004/02
  •  A High-speed Atomic Force Microscope for Studying Biological Macromolecules in Action Ando, T., Kodera, N., Naito, Y., Kinoshita, T., Furuta, K. & Toyoshima, Y. Y. ChemPhysChem 4 11 1196-1202 2003/11
  •  A high-speed atomic force microscope for studying biological macromolecules in action Ando, T., Kodera, N., Maruyama, D., Takai, E., Saito, K. & Toda, A. Jpn. J. Appl. Phys. 41 7B 4851-4856 2002/07
  •  A high-speed atomic force microscope for studying biological macromolecules Ando, T., Kodera, N., Takai, E., Maruyama, D., Saito, K. & Toda, A. Proc. Natl Acad. Sci. USA 98 22 12468-12472 2001/10

Conference Presentations

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「高速原子間力顕微鏡による脚の短いプロセッシブミオシンの運動メカニズムの解明」(2012-2014) 
○「高速原子間力顕微鏡によるミオシン6の運動メカニズムの解明」(2010-2011) 

Classes (Bachelors)

○Presentation and Debate (Freshman Seminar II)(2017)
○Physics Experiments 2(2017)
○Biophysics(2017)
○Exercise in Mechanics 1(2017)
○Fundamental Physics 1(2017)
○Introduction to Region-studies(2017)
○Freshman Seminar I(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Physics Experiments 1(2017)
○Exercise in Mechanics 1(2016)

Classes (Graduate Schools)

○Exercise B(2017)
○Seminar B(2017)
○Nanobiology(2017)
○Nanobiology(2017)
○Nanobiology(2017)
○Nanobiology(2017)
○Biophysics b(2017)
○Introduction to Molecular and Biophysics b(2017)
○Research Work B(2017)
○Introduction to Molecular and Biophysics a(2017)
○Biophysics a(2017)
○Introduction to Molecular and Biophysics a(2016)
○Biophysics a(2016)
○Biophysics b(2016)
○Introduction to Molecular and Biophysics b(2016)
○Seminar B(2016)
○Nanobiology(2016)
○Exercise B(2016)
○Research Work B(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

To Page Top