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Researcher Information

last modified:2023/03/22

Associate Professor YOSHIMURA, Tomoyuki

Faculty, Affiliation

Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field


Academic Background


The University of Tokushima Guraduate School Institute of Health Biosciences (2005/04/01-2005/11/30)
Kyoto university Institute for Chemical Research(2007/04/01-2015/09/30)
Kyoto university Institute for Chemical Reaseach(2005/12/01-2007/03/31)
Kanazawa university(2015/10/01-)

Year & Month of Birth

Academic Society

The Society of Sythtic Organic Chemistry, Japan
The Pharmaceutical Society of Japan
American Chemical Society



Speciality Keywords

Research Themes



  •  Asymmetric Synthesis of a Bicyclo[4.3.0]nonene Derivative Dearing a Quaternary Carbon Stereocenter: Desymmetrization of sigma-Symmetrical Diketones through Intramolecular Addition of an Alkenyl Anion Tomoyuki Yoshimura, Yuki Enami, Jun-ichi Matsuo Synthesis 52 3667-3674 2020/08/20
  •  Development of Nitrolactonization Mediated by Iron (III) Nitrate Nonahydrate Tomoyuki Yoshimura, Yuki Umeda, Risako Takahashi, Jun-ichi Matsuo Chem. Pharm. Bull. 68 12 1220-1225 2020/12/01
  •  Protonation-Assisted Conjugate Addition of Axially Chiral Enolates: Asymmetric Synthesis of beta-Lactams with Contiguous Tetrasubstituted Stereocenters from alpha-Amino Acids via Memory of Chirality Pan Yang, Tomoyuki Yoshimura, Takahiro Sasamori, Norihiro Tokitoh, Kazuhiro Morisaki, Takeo Kawabata Heterocycles 101 2 664-678 2019/10/10
  •  Palladium-catalyzed stereoselective intramolecular cyclization and Suzuki coupling of N-arylsulfonyl-a- chloroenamides promoted by a g-hydroxy group Yuto Yabuuchi, Kenta Sakamoto, Tomoyuki Yoshimura, Jun-ichi Matsuo Tetrahedron 70 30 4053-4061 2018/06/06
  •  Asymmetric Synthesis of beta-Lactams By Intramolecular Conjugate Addition of Serine and Cysteine Derivatives via Memory of Chirality Ryuichi Hyakutake, Tomoyuki Yoshimura, Yoshihiro Ueda, Kazuhiro Hayashi, Takumi Furuta, Takeo Kawabata Heterocycles 92 2 1128-1147 2018/06/22

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  •  Synthesis of 8-Oxabicyclo[3.2.1]octanes by TiCl4-Mediated Reactions of 3-Alkoxycyclobutanones and Allenylsilanes Tatsuo Onnagawa, Mizuki Yamazaki, Tomoyuki Yoshimura, Jun-ichi Matsuo Synlett 29 20 2717-2721 2018/10/29
  •  Formal [4+2] cycloaddition of 3-phenylcyclobutanones with nitriles Emiko Igarashi, Kenta Sakamoto, Tomoyuki Yoshimura, Jun-ichi Matsuo Tetrahedron Letters 60 1 13-15 2018/11/13
  •  Synthesis of multisubstituted phenols by formal [4 + 2] cycloaddition of nucleophilic alkynes with 3- ethoxycyclobutanones Takeo Kuzugichi, Yuto Yabuuchi, Tomoyuki Yoshimura, Jun-ichi Matsuo Organic & BIomolecular Chemistry 15 25 5268-5271 2017/06/05
  •  Reactions of Nitrosobenzenes with Cyclobutanones by Activation with a Lewis Acid Yusuke Shima, Emiko Igarashi, Tomoyuki Yoshimura, Jun-ichi Matsuo Synlett 29 6 723-726 2017/07/05
  •  Friedel-Crafts Alkylation of Aromatics by TiCl4-Promoted Ring Cleavage of 3-Arylcyclobutanones Mayu Kanie, Tomoyuki Yoshimura, Jun-ichi Matsuo Synthesis 50 3 548-554 2017/11/06
  •  alpha-Arylation of alpha-amino acid deriatives with arynes via memory of chirality: asymmetric synthesis of benzocyclobutenones with tetrasubstituted carbon Koji Kasamatsu, Tomoyuki Yoshimura, Attila Mandi, Tohru Taniguchi, Kenji Monde, Takumi Furuta, Takeo Kawabata Organic Letters 19 2 352-355 2017
  •  Asymmetric synthesis of multisubstituted dihydrobenzofurans by intramolecular conjugate addition of short-lived C-O axially chiral enolates Keisuke Tomohara, Koji Kasamatsu, Tomoyuki Yoshimura, Takumi Furuta, Takeo Kawabata Chemical & Pharmaceutical Bulletin 64 7 899-906 2016
  •  Synthesis of alpha-Halo-gamma-hydroxyenamides by Titanium Tetrahalide Mediated Addition of Aldehydes or Ketones to Ynamides Yuto Yabuuchi, Takeo Kuzuguchi, Tomoyuki Yoshimura, Jun-ichi Matsuo Organic Letters 19 19 4951-4953 2016
  •  Formal [4+2] cycloaddition of quinolines, pyridines, and isoquinolines with 3-ethoxycyclobutanones Tatuso Onnagawa, Yusuke Shima, Tomoyuki Yoshimura, Jun-ichi Matsuo Tetrahedron Letters 57 27-28 3050-3052 2016
  •  Catalyst-controlled regiodivergent vinylogous aza-Morita-Baylis-Hillman reactions Ryuichi Hyakutake, Naruhiro Gondo, Yoshihiro Ueda, Tomoyuki Yoshimura, Takumi Furuta, Takeo Kawabata Tetrahedron Letters 57 12 1321-1324 2016
  •  Catalytic asymmetric reactions in alkaloid and terpenoid syntheses Tomoyuki Yoshimura Tetrahedron Letters 55 37 5109-5118 2014
  •  Asymmetric α-Arylation of Amino Acid Derivatives by Clayden Rearrangement of Ester Enolates via Memory of Chirality Keisuke Tomohara, Tomoyuki Yoshimura, Ryuichi Hyakutake, Pan Yang, Takeo Kawabata Journal of the American Chemical Society 135 36 13294-13297 2013
  •  Asymmetric Induction via Short-Lived Chiral Enolates with a Chiral C-O Axis Tomoyuki Yoshimura, Keisuke Tomohara, Takeo Kawabata 135 19 7102-7105 2013
  •  Asymmetric Intermolecular Conjugate Addition of Amino Acid Derivatives via Memory of Chirality: Total Synthesis of Manzacidin A Tomoyuki Yoshimura, Tomohiko Kinoshita, Hiroyasu Yoshioka, Takeo Kawabata Organic Letters 15 4 864-867 2013

Conference Presentations

  • beta-Selective Glycosylation using Unprotected alpha-D-Pyranose(conference:Molecular Chirality Asia 2016)(2016/04/22)
  • Asymmetric alpha-Fluorination of Amino Acid Derivatives via Memory of Chirality(conference:The 3rd International Symposium on Process Chemistry)(2015/07/15)
  • Elongation of Life-Time of Chiral Enolate Intermediates; Asymmetric alpha-Fluorination of Amino Acid Derivatives via Memory of Chirality(conference:27th International Symposium on Chiral Discrimination (ISCD27))(2015/06/29)
  • Synthetic studies on cycloheptatrienes(conference:39th Medicinal chemistry symposium)(2022/11/23)


Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research


Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Lecture on Life in Campus and Society(2022)
○Experiments in Organic Chemistry(2022)
○Pharmaceutical Chemistry(2022)
○Pharmaceutical Organic Synthesis(2022)
○Experiments in Organic Chemistry(2022)
○Pharmaceutical Organic Synthesis(2022)
○Pharmaceutical Chemistry(2021)
○Pharmaceutical Organic Synthesis(2021)
○Experiments in Organic Chemistry(2021)
○Experiments in Organic Chemistry(2020)
○Pharmaceutical Chemistry(2020)
○Pharmaceutical Organic Synthesis(2020)
○Lecture on Life in Campus and Society(2020)
○Laboratory Rotation 3(2019)
○Lecture on Life in Campus and Society(2019)
○Presentation and Debate (Freshman Seminar II)(2019)
○Experiments in Organic Chemistry(2019)
○Pharmaceutical Chemistry(2019)
○Pharmaceutical Organic Synthesis(2019)
○Pharmaceutical Chemistry(2018)
○Experiments in Organic Chemistry(2018)
○Pharmaceutical Organic Synthesis(2018)
○Lecture on Life in Campus and Society(2018)
○Pharmaceutical Chemistry(2017)
○Pharmaceutical Chemistry(2017)
○Experiments in Organic Chemistry(2017)
○Pharmaceutical Organic Synthesis(2017)
○Lecture on Life in Campus and Society(2017)
○Freshman Seminar I(2016)
○Pharmaceutical Organic Synthesis(2016)
○Experiments in Organic Chemistry(2016)

Classes (Graduate Schools)

○Advanced Course of Pharmachemistry(2022)
○Introduction to Pharmachemistry(2022)
○Introduction to Discovering Molecular Probes Ⅰ(2019)
○Introduction to Advanced Organic Chemistry(2019)
○Advanced Course of Pharmachemistry(2019)
○Stereocontrolled Syntheses of Functional Molecules(2019)
○Advanced Seminar on Pharmachemistry(2019)
○Introduction to Discovering Molecular Probes Ⅱ(2019)
○Introduction to Pharmachemistry(2019)
○Advanced Organic Chemistry III(2017)
○Introduction to Advanced Organic Chemistry(2017)
○Stereocontrolled Syntheses of Functional Molecules(2017)
○Advanced Organic Chemistry II(2017)
○Advanced Course of Pharmachemistry(2017)
○Advanced Organic Chemistry I(2017)
○Advanced Seminar on Pharmachemistry(2017)
○Introduction to Pharmaceutical Sciences(2016)
○Advanced Organic Chemistry II(2016)
○Advanced organic chemistry II(2015)

International Project

International Students

Lecture themes

Others (Social Activities)

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