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Researcher Information

last modified:2020/04/10

Assistant Professor KAWAHARA, Hironori

Laboratory Website

Faculty, Affiliation


College and School Educational Field


immunology TEL:076-265-2727 FAX:076-265-2734

Academic Background

【Academic background(Doctoral/Master's Degree)】
Keio University School of Medicine Doctor Graduate School of Medicine Physiology


Osaka University IFReC Postdoctoral Research Fellow
University of Pennsylvania Cell & Developmental Biology Perelman School of Medicine Postdoctoral Fellow
Keio University School of Medicine School of Medicine

Year & Month of Birth

Academic Society



Neuroimmunology, RNA Biology, Developmental Biology

Speciality Keywords

Exosome, Neuroimmunology, RNA Biology, Neural Stem Cell

Research Themes



  •  The Role of Exosomes/Extracellular Vesicles in Neural Signal Transduction. Kawahara H, Hanayama R. Biological & pharmaceutical bulletin 41 8 1119-1125  2018
  •  Behavior of Neuronal Exosomes in Synaptic Communication Hironori Kawahara, Rie Nakatani, Taishi Tsutsui, Sunao Haitani, Shunsuke Kishimoto, Rikinari Hanayama RMRJ 48 1 24-29 2017/01/10
  •  Characterization of the RNA-binding protein Musashi1 in zebrafish. Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Brain Res.  1462 162-73 2012
  •  MicroRNAs in Neural Stem Cells and Neurogenesis. Kawahara H, Imai T, Okano H. Front Neurosci. 6 30 2012
  •  Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H. J Biol Chem. 286 18 16121-30 2011

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  •  Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. J Cell Biol. 184 4 639-53 2008
  •  Function of RNA-binding protein Musashi-1 in stem cells. Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Exp Cell Res. 306 2 349-56 2005

Conference Presentations

Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research

○Grant-in-Aid for Young Scientists (B)「RNA-binding protein Musashi1-mediated miRNA regulation」(2009-2010) 
○Grant-in-Aid for Research Activity start-up「神経系exosomeに内包する新規レビー小体認知症関連ncRNAの同定と機能解明」(2013-2015) 
○Grant-in-Aid for Scientific Research (C)「パーキンソン病原因遺伝子SNCAのexosomeを介した伝播分子制御機構の解明」(2015-2018) 

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

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