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Researcher Information

last modified:2022/03/17

Assistant Professor KAWAHARA, Hironori

Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences immunology

College and School Educational Field


immunology TEL:076-265-2727 FAX:076-265-2734

Academic Background

【Academic background(Doctoral/Master's Degree)】
Keio University School of Medicine Doctor Graduate School of Medicine Physiology


Osaka University IFReC Postdoctoral Research Fellow
University of Pennsylvania Cell & Developmental Biology Perelman School of Medicine Postdoctoral Fellow
Keio University School of Medicine School of Medicine

Year & Month of Birth

Academic Society



Neuroimmunology, RNA Biology, Developmental Biology

Speciality Keywords

Exosome, Neuroimmunology, RNA Biology, Neural Stem Cell

Research Themes



  •  Tumor-secreted proliferin-1 regulates adipogenesis and lipolysis in cachexia. Tuan Duc Nguyen, Yuji Miyatake, Takeshi Yoshida, Hironori Kawahara, Rikinari Hanayama. Int J Cancer 15 148 1982-1992 2021
  •  Glioma-derived extracellular vesicles promote tumor progression by conveying WT1. Taishi Tsutsui, Hironori Kawahara, Ryouken Kimura, Yu Dong, Shabierjiang Jiapaer, Hemragul Sabit, Jiakang Zhang, Takeshi Yoshida, Mitsutoshi Nakada, Rikinari Hanayama  Carcinogenesis 41 9 1238-1245 2020
  •  The Role of Exosomes/Extracellular Vesicles in Neural Signal Transduction. Kawahara H, Hanayama R. Biological & pharmaceutical bulletin 41 8 1119-1125  2018
  •  Behavior of Neuronal Exosomes in Synaptic Communication Hironori Kawahara, Rie Nakatani, Taishi Tsutsui, Sunao Haitani, Shunsuke Kishimoto, Rikinari Hanayama RMRJ 48 1 24-29 2017/01/10
  •  Characterization of the RNA-binding protein Musashi1 in zebrafish. Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Brain Res.  1462 162-73 2012

show all

  •  MicroRNAs in Neural Stem Cells and Neurogenesis. Kawahara H, Imai T, Okano H. Front Neurosci. 6 30 2012
  •  Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H. J Biol Chem. 286 18 16121-30 2011
  •  Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. J Cell Biol. 184 4 639-53 2008
  •  Function of RNA-binding protein Musashi-1 in stem cells. Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Exp Cell Res. 306 2 349-56 2005

Conference Presentations


Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research

○Grant-in-Aid for Young Scientists (B)「RNA-binding protein Musashi1-mediated miRNA regulation」(2009-2010) 
○Grant-in-Aid for Research Activity start-up「神経系exosomeに内包する新規レビー小体認知症関連ncRNAの同定と機能解明」(2013-2015) 
○Grant-in-Aid for Scientific Research (C)「パーキンソン病原因遺伝子SNCAのexosomeを介した伝播分子制御機構の解明」(2015-2018) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

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