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Researcher Information

last modified:2024/04/04

Professor KINUYA Seigo

Mail Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences
Professor
Vice President, University Hospital

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of Nuclear Medicine TEL:076-265-2333 FAX:076-234-4257

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Graduate School, Division of Medicine Internal medicine, NUclear Medicine 199003 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University Medicine 198603
【Degree】
MD

Career

Kanazawa University University Hospital Vice President(2016/04/01-)
Kanazawa University University Hospital Director aide(2014/04/01-2016/03/31)
Kanazawa University University Hospital Vice President(2012/04/01-2014/03/31)
Kanazawa University Institute of Medical. Pharmaceutical and Health Sciences, Department of Nuclear Medicine Professor(2006/10/16-)
Kanazawa University University Hospital, Department of Nuclear Medicine Assisstant Professor(2006/04/01-2006/10/15)
School of Medicine, Kanazawa University Department of Nuclear Medicine Assisstant(1995/10/01-2006/03/31)
School of Medicine, Kanazawa University Department of Nuclear Medicine Staff doctor(1992/11/01-1995/09/30)
National Institutes of Health, USA Clinical Center, Deapartment of Nuclear Medicine Visiting fellow(1990/10/29-1992/10/31)
School of Medicine, Kanazawa University Department of Nuclear Medicine Staff doctor(1990/08/01-1990/10/28)
Hokuriku Central Hospital Internal Medicine Staff doctor(1990/04/01-1990/07/31)

Year & Month of Birth

Academic Society





Japanese Society of Nuclear Medicine
Japanese Society of Nuclear Medicine
Japanese Society of Nuclear Medicine


JASCC

Japanese Society of Nuclear Medicine
Society of Nuclear Medicine









Multinational Association of Supportive Care in Cancer
World Federation of Nuclear Medicine and Biology

Asia Oceania Federation of Nuclear Medicine and Biology
World Association of Radiopharmaceutical Therapy

Award

○Top Reviewer Certificate(2021/02/26)
○Top Reviewer Certificate(2019/12/18)
○Second Place Poster - Cardiovascular (2019/06/25)
○Magna Cum Laude (Europaen Association of Nuclear Medicine)(2000/09/01)
○Magna Cum Laude (Europaen Association of Nuclear Medicine)(2000/09/01)
○Magna Cum Laude (Europaen Association of Nuclear Medicine)(2000/09/01)
○Magna Cum Laude (Europaen Association of Nuclear Medicine)(2000/09/01)
○Best Science Paper in European Journal of Nuclear Medicine(2002/09/04)
○Best Science Paper in European Journal of Nuclear Medicine(2002/09/04)

Specialities

Nuclear Medicine、、Biomolecular chemistry

Speciality Keywords

Nuclear Medicine, radionuclide therapy

Research Themes

Tumor detection and treatment with radiopharmaceuticals

Books

  •  Combined radioimmunotherapy with antiangiogenic therapy to treat cancer: validation studies in animal models Nova Science Publishers, Inc.
  •  Assessment of cancer drug resistance with nuclear medicine images Nova Science Publishers, Inc
  •  Li X-F, Bai J, Yokoyama K, Michigishi T, Tonami N Prediction of therapeutic responses to chemotherapy and monitor of effects of MDR-modulation with radiotracers in malignant tumors Nova Science Publishers, Inc 2006/11
  •  若林大志、稲木杏吏、萱野大樹、絹谷セイゴ 内分泌腫瘍(第2版) 2020/09/30

Papers

  •  Manual on the proper use of the 211At‑labeled PSMA ligand ([211At]PSMA‑5) for clinical trials of targeted alpha therapy (1st edition) Watabe T, Namba M, Yanagida S, Nakamura Y, Yamada T, Tatsuno S, Ri A, Yoshida S, Uyama K, Kinuya S, Tomiyama N, Hosono M. Ann Nucl Med 2024/03/28
  •  Optimizing the pharmacokinetics of an 211At-labeled RGD peptide with an albumin-binding moiety via the administration of an albumin-binding inhibitor Hiroaki Echigo, Masayuki Munekane, Takeshi Fuchigami, Kohshin Washiyama, Kenji Mishiro, Hiroshi Wakabayasi, Kazuhiro Takahashi, Seigo Kinuya, Kazuma Ogawa Eur J Nucl Med Mol Imaging 2024/03/21
  •  Synthesis and evaluation of radiogallium labeled bone imaging probes using oligo-γ-carboxy glutamic acid peptides as carriers to bone Kazuma Ogawa, Kota Nishizawa, Kenji Mishiro, Nurmaya Effendi, Takeshi Fuchigami, Masayuki Munekane, Hiroshi Wakabayashi, Seigo Kinuya Molecular Pharmaceutics 2024/03/20
  •  Flare phenomenon visualized by 99mTc-bone scintigraphy has prognostic value for patients with metastatic castration-resistant prostate cancer Xue Zhang, Kenichi Nakajima, Atsushi Mizokami, Hiroyuki Horikoshi, Koshiro Nishimoto, Katsuyoshi Hashine, Hideyasu Matsuyama, Satoru Takahashi, Hiroshi Wakabayashi, Seigo Kinuya  Ann Nucl Med 2024/03/13
  •  Myocardial perfusion imaging with retrospective gating and integrated correction of attenuation, scatter, respiration, motion, and arrhythmia. Nakajima K, Shibutani T, Massanes F, Shimizu T, Yoshida S, Onoguchi M, Kinuya S, Vija AH. J Nucl Cardiol 2023/09/27

show all

  •  Transthyretin amyloid cardiomyopathy disease burden quantified using 99mTc-pyrophosphate SPECT/CT: volumetric parameters versus SUVmax ratio at 1 and 3 hours Satoru Watanabe, Kenichi Nakajima, Fumihito Toshima, Hiroshi Wakabayashi, Shohei Yoshida, Hiroto Yoneyama, Junji Komatsu, Takahiro Konishi, Seigo Kinuya J Nucl Cardiol 2023/08/22
  •  125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia. Wakabayashi H, Mori H, Hiromasa T, Akatani N, Inaki A, Kozaka T, Kitamura Y, Ogawa K, Kinuya S, Taki J. J Nucl Cardiol 30 2 653-661 2023/08/01
  •  Development of probes for radiotheranostics with albumin binding moiety to increase the therapeutic effects of astatine-211 (211At). Echigo H, Mishiro K, Munekane M, Fuchigami T, Washiyama K, Takahashi K, Kitamura Y, Wakabayashi H, Kinuya S, Ogawa K. Eur J Nucl Med Mol Imaging 2023/10/11
  •  Influence of spill-over for 99mTc images and the effect of scatter correction for dual-isotope simultaneous acquisition with 99mTc and 18F using small-animal SPECT-PET/CT system. Shibutani T, Onoguchi M, Kanno T, Kinuya S. Phys Eng Sci Med 2023/10/30
  •  Astatine-211-labeled aza-vesamicol derivatives as sigma receptor ligands for targeted alpha therapy Kazuma Ogawa, Kota Nishizawa, Kohshin Washiyama, Masayuki Munekane , Takeshi Fuchigami, Hiroaki Echigo, Kenji Mishiro, Saki Hirata, Hiroshi Wakabayashi, Kazuhiro Takahashi, Seigo Kinuya Nuclear Medicine and Biology 122-123 2023/07/28
  •  Three-Dimensional Heart Segmentation and Absolute Quantitation of Cardiac 123I-metaiodobenzylguanidine Sympathetic Imaging Using SPECT/CT Saito S, Nakajima K, Shibutani T, Wakabayashi H, Yoneyama H, Konishi T, Mori H, Takata A, Kinuya S. Ann Nucl Cardiol. 2023;9(1):61-67 9 1 61-67 2023/10/31
  •  Myocardial perfusion imaging with retrospective gating and integrated correction of attenuation, scatter, respiration, motion, and arrhythmia Kenichi Nakajima , Takayuki Shibutani , Francesc Massanes, Takeshi Shimizu, Shohei Yoshida, Masahisa Onoguchi, Seigo Kinuya & A. Hans Vija  J Nucl Cardiol  30 2773-2789 2023/09/27
  •  Radiation exposure lymphocyte damage assessed by γ-H2AX level using flow cytometry Chen Z, Wakabayashi H, Kuroda R, Mori H, Hiromasa T, Kayano D, Kinuya S Sci Rep 14 1 4339 2024/02/22
  •  Theranostic Radiopharmaceuticals: A Universal Challenging Educational Paradigm in Nuclear Medicine Urbain JL, Scott AM, Lee ST, Buscombe J, Weston C, Hatazawa J, Kinuya S, Singh B, Haidar M, Ross A, Lamoureux F, Kunikowska J, Wadsak W, Dierckx R, Paez D, Giammarile F, Lee KH, O JH, Moshe M, Louw L, More S, Nadel H, Lee D, Wahl R. J Nucl Med  64 6 986-91 2023/05/04
  •  Comparison of muscle activity, strength, and balance, before and after a 6-month training using the FIFA11+ program (part 2). Oshima T, Nakase J, Inaki A, Mochizuki T, Takata Y, Shimozaki K, Kinuya S, Tsuchiya H. J Orthop Surg (Hong Kong) 28 1 2309499019891541 2020/01
  •  Calibrated scintigraphic imaging procedures improve quantitative assessment of the cardiac sympathetic nerve activity Koichi Okuda, Kenichi Nakajima, Chiemi Kitamura, Yumiko Kirihara, Mitsumasa Hashimoto & Seigo Kinuya  Scientific Report 10 21834  2020/12/14
  •  Thallium-201 Imaging in Intact Olfactory Sensory Neurons with Reduced Pre-Synaptic Inhibition In Vivo. Shiga H, Wakabayashi H, Washiyama K, Noguchi T, Hiromasa T, Miyazono S, Kumai M, Ogawa K, Taki J, Kinuya S, Miwa T. Mol Neurobiol 2020/08/20
  •  A phase I clinical trial for [131I]meta-iodobenzylguanidine therapy in patients with refractory pheochromocytoma and paraganglioma. Wakabayashi H, Inaki A, Yoshimura K, Murayama T, Imai Y, Higuchi T, Jinguji M, Shiga T, Kinuya S Sci Rep. 1 9 7625 2019/05/01
  •  Introduction of the targeted alpha therapy (with Radium-223) into clinical practice in Japan: learnings and implementation Hosono M, Ikebuchi H, Nakamura Y, Yanagida S, Kinuya S Ann Nucl Med 2019
  •  Design, synthesis, and biological evaluation of radioiodinated benzo[d]imidazolequinoline derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging nurmaya effendi, Kenji Mishrio, Takeshi Takarada, Daisuke Yamada, Ryuichi Nishii, Kazuhiro Shiba, Seigo Kinuya, Akira ODANI, Kazuma Ogawa Bioorganic & Medicinal Chemistry 2019
  •  Development of Radiogallium-Labeled Peptides forPlatelet-Derived Growth Factor Receptorβ(PDGFRβ) Imaging:Influence of Different Linkers Nurmaya Effendi , Kenji Mishiro , Kazuhiro Shiba, Seigo Kinuya and Kazuma Ogawa Molecules 26 41 2020/12/23
  •  The utility of heart-to-mediastinum ratio using a planar image created from IQ-SPECT with iodine-123 meta-iodobenzylguanidine Shibutani T, Nakajima K, Yoneyama H, Konishi T, Okuda K, Onoguchi M, Kinuya S J Nucl Cardiol 2020/02/10
  •  Utility of bone SPECT/CT to identify the primary cause of pain in elderly patients with degenerative lumbar spine disease. Kato S, Demura S, Matsubara H, Inaki A, Shinmura K, Yokogawa N, Murakami H, Kinuya S, Tsuchiya H. J Orthop Surg Res 14 1 185 2019/06/20
  •  Nuclear medicine practice in Japan: a report of the eighth nationwide survey in 2017. Nishiyama Y, Kinuya S, Kato T, Kayano D, Sato S, Tashiro M, Tatsumi M, Hashimoto T, Baba S, Hirata K, Yoshimura M, Yoneyama H Ann Nucl Med 2019/06/24
  •  A Report on Health Resource Use in Internal Radiation Therapy with Radium Chloride (223Ra) (2nd Survey) Seigo KINUYA,Katsuhiko KATO,Takeshi KAMIOKA,Toshiyuki SHIMMURA,Yoshinori MATOBA,Kengo ITO, KAKUIGAKU 54 1 603-621 2017
  •  甲状腺癌の放射性ヨウ素内用療法におけるRI 治療病室稼働状況の実態調査報告(第4 報) 54 1 579–586 2017
  •  Utility of 123I-MIBG Standardized Uptake Value in Patients with Refractory Pheochromocytoma and Paraganglioma. Wakabayashi H, Konishi T, Yoneyama H, Inaki A, Hiromasa T, Yamase T, Akatani N, Watanabe S, Mori H, Kayano D, Kinuya S. Asia Ocean J Nucl Med Biol. 7 2 115-120 2019
  •  Radiation exposure in nurses during care of 131I-MIBG therapy for pediatric patients with high-risk neuroblastoma. Taniguchi Y, Wakabayashi H, Inaki A, Kayano D, Yamada M, Kinuya S. 2020/04/15
  •  Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging. Ogawa K, Masuda R, Mishiro K, Wang M, Kozaka T, Shiba K, Kinuya S, Odani A. Bioorg Med Chem. 10 27 1990-1996 2019/05/15
  •  Imaging modalities for drug-related osteonecrosis of the jaw (5), utility of bone scintigraphy and 18F-FDG PET/CT in early detection and risk assessment of medication-related osteonecrosis of the jaw (secondary publication). Watanabe S, Nakajima K, Kinuya S. Jpn Dent Sci Rev 1 55 76-79 2019
  •  A phase I clinical trial for [131I]meta-iodobenzylguanidine therapy in patients with refractory pheochromocytoma and paraganglioma: a study protocol. Inaki A, Yoshimura K, Murayama T, Imai Y, Kuribayashi Y, Higuchi T, Jinguji M, Shiga T, Kinuya S. J Med Invest 64 3,4 205-209. 2017
  •  Influence of Attenuation Correction by Brain Perfusion SPECT/CT Using a Simulated Abnormal Bone Structure: Comparison Between Chang and CT Methods. Shibutani T, Onoguchi M, Miyamoto N, Yamamoto Y, Kinuya S. J Nucl Med Technol. 45 3 208-213 2017
  •  Design, synthesis, and biological evaluation of radioiodinated benzo[d]imidazole-quinoline derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging. Effendi N, Mishiro K, Takarada T, Yamada D, Nishii R, Shiba K, Kinuya S, Odani A, Ogawa K. Bioorg Med Chem. 2 27 383-393 2019/01
  •  targeted radionuclide therapy with 131I-MIBG Current therapy 37 2 49-55 2019/02/01
  •  Front line of thyroid tumor treatment Current trend of the treatment Radioactive iodine therapy Kinuya S 91 6 566-571 2019/06
  •  Reliability of the muscle strength measurement and effects of the strengthening by an innovative exercise device for the abdominal trunk muscles. Kato S, Inaki A, Murakami H, Kurokawa Y, Mochizuki T, Demura S, Yoshioka K, Yokogawa N, Yonezawa N, Shimizu T, Kinuya S, Tsuchiya H. J Back Musculoskelet Rehabil.  2019/10/15
  •  current status of radioactive iodine therapy for thyroid cancer 89 10 900-908 2017
  •  Manual on the proper use of yttrium-90-labeled anti-P-cadherin antibody injection for radionuclide therapy in clinical trials. Hosono M, Ikebuchi H, Kinuya S, Yanagida S, Nakamura Y, Yamada T, Sakaguchi K, Sugano H, Kojima K, Hatazawa J. Ann Nucl Med. 33 11 787-805 2019/11
  •  A randomized, double-blind, comparison of radium-223 and placebo, in combination with abiraterone acetate and prednisolone, in castration-resistant metastatic prostate cancer: subgroup analysis of Japanese patients in the ERA 223 study. Matsubara N, Kimura G, Uemura H, Uemura H, Nakamura M, Nagamori S, Mizokami A, Kikukawa H, Hosono M, Kinuya S, Krissel H, Siegel J, Kakehi Y. Int J Clin Oncol.  2019/12/10
  •  Introduction of the targeted alpha therapy (with Radium-223) into clinical practice in Japan: learnings and implementation. Hosono M, Ikebuchi H, Nakamura Y, Yanagida S, Kinuya S. Ann Nucl Med 3 33 211-221 2019/03
  •  Accuracy of an artificial neural network for detecting a regional abnormality in myocardial perfusion SPECT. Shibutani T, Nakajima K, Wakabayashi H, Mori H, Matsuo S, Yoneyama H, Konishi T, Okuda K, Onoguchi M, Kinuya S. Ann Nucl Med 2 33 86-92 2019/02
  •  Three-year follow-up of a phase II study of radium-223 dichloride in Japanese patients with symptomatic castration-resistant prostate cancer and bone metastases. Uemura H, Uemura H, Nagamori S, Wakumoto Y, Kimura G, Kikukawa H, Yokomizo A, Mizokami A, Kosaka T, Masumori N, Kawasaki Y, Yonese J, Nasu Y, Fukasawa S, Sugiyama T, Kinuya S, Hosono M, Yamaguchi I, Akagawa T, Matsubara N. Int J Clin Oncol 24 5 557-566 2019
  •  Characteristics of single- and dual-photopeak energy window acquisitions with thallium-201 IQ-SPECT/CT system. Shibutani T, Onoguchi M, Yoneyama H, Konishi T, Matsuo S, Nakajima K, Kinuya S. Ann Nucl Med 31 7 529-535 2017
  •  IQ-SPECT for thallium-201 myocardial perfusion imaging: effect of normal databases on quantification. Konishi T, Nakajima K, Okuda K, Yoneyama H, Matsuo S, Shibutani T, Onoguchi M, Kinuya S. Ann Nucl Med 31 6 454-461 2017
  •  Targeted alpha therapy with 223Ra for castration-resistant bone metastases of prostate cancer 33 4 431-441 2017
  •  去勢抵抗性前立腺がん骨転移に対する223Raα線内用療法 Clinical Imagiology 33 4 431-441 2017/04
  •  Safety and efficacy of radium-223 dichloride in Japanese patients with castration-resistant prostate cancer and bone metastases Uemura H, Uemura H, Matsubara N, Kinuya S, Hosono M, Yajima Y, Doi T Int J Clin Oncol 2017/05/06
  •  Simultaneous acquisition of (99m)Tc- and (123)I-labeled radiotracers using a preclinical SPECT scanner with CZT detectors. Simultaneous acquisition of (99m)Tc- and (123)I-labeled radiotracers using a preclinical SPECT scanner with CZT detectors. Ann Nucl Med 30 4 263-271 2016
  •  Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion. Wakabayashi H, Taki J, Inaki A, Shiba K, Matsunari I, Kinuya S. EJNMMI Res 5 1 72 2015
  •  Synthesis and evaluation of a new vesamicol analog o-[(11)C]methyl-trans-decalinvesamicol as a PET ligand for the vesicular acetylcholine transporter. Kitamura Y, Kozaka T, Miwa D, Uno I, Azim MA, Ogawa K, Taki J, Kinuya S, Shiba K. Ann Nucl Med 30 2 122-129 2016
  •  Methods of calculating 123I‑β‑methyl‑P‑iodophenyl‑pentadecanoic acid washout rates in triglyceride deposit cardiomyovasculopathy Zhuoqing Chen, Kenichi Nakajima, Ken-ichi Hirano, Takashi Kamiya, Shohei Yoshida, Shintaro Saito, Seigo Kinuya  Ann Nucl Med 36 11 986–997 2022/09/25
  •  Exploratory Analysis Results from Post-marketing Surveillance Study of Radium-223 in Japanese Patients with Castration-resistant Prostate Cancer and Bone Metastases: Subgroup Analysis by Age Hosono M, Uemura H, Kakehi Y, Masumori N, Takahashi S, Okayama Y, Sunaya T, Horio T, Kinuya S. Kaku Igaku 58 1 91-101 2021/10/01
  •  Convolutional neural network-based automatic heart segmentation and quantitation in 123 I-metaiodobenzylguanidine SPECT imaging Saito S, Nakajima K, Edenbrandt L, Enqvist O, Ulén J, Kinuya S. EJNMMI Res 11 1 105 2021/10/12
  •  Manual on the proper use of sodium astatide ([211At]NaAt) injections in clinical trials for targeted alpha therapy (1st edition).  Watabe T, Hosono M, Kinuya S, Yamada T, Yanagida S, Namba M, Nakamura Y. Ann Nucl Med 35 7 753-766 2021/07/01
  •  A Radiobrominated Tyrosine Kinase Inhibitor for EGFR with L858R/T790M Mutations in Lung Carcinoma. Fawwaz M, Mishiro K, Nishii R, Makino A, Kiyono Y, Shiba K, Kinuya S, Ogawa K. Pharmaceuticals (Basel) 14 3 256 2021/03/12
  •  Comparison of the detecting capability between 123I-mIBG and post-therapeutic 131I-mIBG scintigraphy for curie scoring in patients with neuroblastoma after chemotherapy. Qiu ZL, Saito S, Kayano D, Wakabayashi H, Kinuya S. Ann Nucl Med 35 6 649-661 2021/07/01
  •  Prognostic factors for refractory pheochromocytoma and paraganglioma after 131I-metaiodobenzylguanidine therapy  Hiromasa T, Wakabayashi H, Kayano D, Inaki A, Watanabe S, Mori H, Akatani N, Yamase T, Kunita Y, Saito S, Kinuya S. Ann Nucle Med 2021/10/13
  •  Skeletal muscle metabolism on whole-body positron emission tomography during pitching Takata Y, Nakase J, Inaki A, Mochizuki T, Shimozaki K, Asai K, Kinuya S, Tsuchiya H. J Int Soc Sports Nutr 18 1 21 2021/03/01
  •  Clinical practice guidelines for high-resolution breast PET, 2019 edition.  Satoh Y, Kawamoto M, Kubota K, Murakami K, Hosono M, Senda M, Sasaki M, Momose T, Ito K, Okamura T, Oda K, Kuge Y, Sakurai M, Tateishi U, Fujibayashi Y, Magata Y, Yoshida T, Waki A, Kato K, Hashimoto T, Uchiyama M, Kinuya S, Higashi T, Magata Y, Machitori A, Maruno H, Minamimoto R, Yoshinaga K. Ann Nucl Med 35 3 406-414 2021/03/01
  •  Metal artifact reduction for improving quantitative SPECT/CT imaging.  Konishi T, Shibutani T, Okuda K, Yoneyama H, Moribe R, Onoguchi M, Nakajima K, Kinuya S Ann Nucl Med 35 3 291-298 2021/01/18
  •  In vitro and in vivo evaluation of [ 125/123 I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([ 125/123 I]-OI5V) as a potential sigma-1 receptor ligand for SPECT  Ann Nucl Med 35 2 167-175 2021/01/08
  •  Colchicine treatment early after infarction attenuates myocardial inflammatory response demonstrated by 14C-methionine imaging and subsequent ventricular remodeling by quantitative gated SPECT Mori H, Taki J, Wakabayashi H, Hiromasa T, Inaki A, Ogawa K, Shiba K, Kinuya S. Ann Nucl Med 35 2 253-259 2021/01/03
  •  Visualization of Dynamic Expression of Myocardial Sigma-1 Receptor After Myocardial Ischemia and Reperfusion Using Radioiodine-Labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) Imaging Hiroshi Wakabayashi, Junichi Taki, Hiroshi Mori, Tomo Hiromasa, Norihito Akatani, Anri Inaki, Takashi Kozaka, Kazuhiro Shiba, Kazuma Ogawa, Seigo Kinuya Circulation Journal 2021/06/26
  •  Medical Innovation Course - achievements in 5 years and future perspective Seigo Kinuya 34 5 326-329 2018
  •  Precision medicine and nuclear medicine therapy Kinuya S 32 1 26-29 2019/01/30
  •  Peptide receptor radionuclide therapy (PRRT) for pancreatic neuroendocrine tumor Seigo Kinuya 38 12 1413-1418 2017
  •  Radiotherapy for neuroendocrine tumors - including PRRT Seigo Kinuya 13 4 309-312 2017
  •  Serial examination of cardiac function and perfusion in growing rats using SPECT/CT for small animals. Hiromasa T, Taki J, Wakabayashi H, Inaki A, Okuda K, Shibutani T, Shiba K, Kinuya S. Sci Rep 10 1 160 2020
  •  Radiation Emission Rate of PET Acquisition in Routine Whole-Body 18F-FDG PET-CT Procedures Ca˜nizares HG, Wakabayashi H, Takeda S, Mochizuki T and Kinuya S AIP Conference Proceedings 2295 020017  2020/12/01
  •  Fully automated analysis for bone scintigraphy with artificial neural network: usefulness of bone scan index (BSI) in breast cancer. Inaki A, Nakajima K, Wakabayashi H, Mochizuki T, Kinuya S Ann Nucl Med 2019/07/17
  •  Decreasing undesirable absorbed radiation to the intestine after administration of radium-223 dichloride for treatment of bone metastases. Ogawa K, Higashi T, Mishiro K, Wakabayashi H, Shiba K, Odani A, Kinuya S. Sci Rep.  10 1 11917 2020/07/17
  •  (-)-o-[11C]methyl-trans-decalinvesamicol ((-)-[11C]OMDV) as a PET ligand for the vesicular acetylcholine transporter Synapse 2020/06/03
  •  Prognostic Value of Early Evaluation of Left Ventricular Dyssynchrony After Myocardial Infarction.   Wakabayashi H, Taki J, Inaki A, Hiromasa T, Yamase T, Akatani N, Okuda K, Shibutani T, Shiba K, Kinuya S. Mol Imaging Biol. 2019
  •  Nasal thallium-201 uptake in patients with parosmia with and without hyposmia after upper respiratory tract infection Hideaki Shiga, Koichi Okuda, Junichi Taki, Naoto Watanabe, Hisao Tonami, Seigo Kinuya, Takaki Miwa International Journal of Allerrgy & Rhinology 2019/07/04
  •  Assessment of neoadjuvant chemotherapy by scintigraphic images J Jpn Orthop Assoc 92 953-958 2018
  •  Synthesis and Evaluation of a Dimeric RGD Peptide as a Preliminary Study for Radiotheranostics with Radiohalogens  iroaki Echigo, Kenji Mishiro, Takeshi Fuchigami, Kazuhiro Shiba, Seigo Kinuya and Kazuma Ogawa Molecules 26 6107 2021/10/11
  •  Accuracy of an artificial neural network for detecting a regional abnormality in myocardial perfusion SPECT.   Shibutani T, Nakajima K, Wakabayashi H, Mori H, Matsuo S, Yoneyama H, Konishi T, Okuda K, Onoguchi M, Kinuya S. Ann Nucl Med 2019
  •  Synthesis and evaluation of a multifunctional probe with a high affinity for prostate-specific membrane antigen (PSMA) and bone. Hirata S, Mishiro K, Higashi T, Fuchigami T, Munekane M, Arano Y, Kinuya S, Ogawa K. Nucl Med Biol 114-115 34-41 2022/08/24
  •  Development of a novel small-animal myocardial phantom can evaluate the image quality of dual-isotope simultaneous acquisition (DISA) Shibutani T, Onoguchi M, Kanno T, Wakabayashi H, Hiromasa T, Kinuya S. Ann Nucl Med 36 12 1031-1038 2022/10/13
  •  Development of tumor-targeting aza-vesamicol derivatives with high affinity for sigma receptors for cancer theranostics Mishiro K, Wang M, Hirata S, Fuchigami T, Shiba K, Kinuya S, Ogawa K. RSC Med Chem 13 8 986-997 2022/06/30
  •  Current Trends and Issues in Therapeutic Nuclear Medicine and Proposed Solutions  Inaki A, Kinuya S. Gan To Kagaku Ryoho 49 8 853-859 2022/08/01
  •  125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia. Wakabayashi H, Mori H, Hiromasa T, Akatani N, Inaki A, Kozaka T, Kitamura Y, Ogawa K, Kinuya S, Taki J. J Nucl Cardiol 2022/08/01
  •  Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA0-Tyr3-octreotate in combination with amino acid solution infusion in Japanese patients with somatostatin receptor-positive, progressive neuroendocrine tumors.  Kobayashi N, Takano S, Ito K, Sugiura M, Ogawa M, Takeda Y, Okubo N, Suzuki A, Tokuhisa M, Kaneta T, Utsunomiya D, Hata M, Inoue T, Hosono M, Kinuya S, Ichikawa Y. Ann Nucl Med 2021/09/17
  •  治療用放射性医薬品 131I-MIBG を投与された患者の退出に係る放射線防護上の検討 稲木 杏吏, 若林 大志, 萱野 大樹, 絹谷 清剛 58 1 59-66 2021/07/12
  •  Synthesis and evaluation of radiogallium-labeled long-chain fatty acid derivatives as myocardial metabolic imaging agents Nurmaya Effendi, Kenji Mishiro, Hiroshi Wakabayashi, Malwina Gabryel-Skrodzka, Kazuhiro Shiba, Junichi Taki, Renata Jastrząb, Seigo Kinuya, Kazuma Ogawa Pros One 16 12 e0261226 2021/12/15
  •  Synthesis and Evaluation of a Dimeric RGD Peptide as a Preliminary Study for Radiotheranostics with Radiohalogens.  Echigo H, Mishiro K, Fuchigami T, Shiba K, Kinuya S, Ogawa K Molecules 26 20 6107 2021/10/10
  •  Feasibility of 125I-RGD uptake as a marker of angiogenesis after myocardial infarction.  Yamase T, Taki J, Wakabayashi H, Inaki A, Hiromasa T, Mori H, Akatani N, Ogawa K, Shiba K, Kinuya S.  Ann Nucl Med 2021/11/26
  •  Phase I/II clinical trial of high-dose [131I] meta-iodobenzylguanidine therapy for high-risk neuroblastoma preceding single myeloablative chemotherapy and haematopoietic stem cell transplantation. Kuroda R, Wakabayashi H, Araki R, Inaki A, Nishimura R, Ikawa Y, Yoshimura K, Murayama T, Imai Y, Funasaka T, Wada T, Kinuya S. Eur J Nucl Med Mol Imaging 2021/11/27
  •  An open-label, single-arm, multi-center, phase II clinical trial of single-dose [131I]meta-iodobenzylguanidine therapy for patients with refractory pheochromocytoma and paraganglioma. Inaki A, Shiga T, Tsushima Y, Jinguji M, Wakabayashi H, Kayano D, Akatani N, Yamase T, Kunita Y, Watanabe S, Hiromasa T, Mori H, Hirata K, Watanabe S, Higuchi T, Tomonaga H, Kinuya S. Ann Nucl Med 2021/12/06
  •  Volumetric evaluation of 99mTc-pyrophosphate SPECT/CT for transthyretin cardiac amyloidosis: Methodology and correlation with cardiac functional parameters. Watanabe S, Nakajima K, Wakabayashi H, Yoneyama H, Yoshida S, Komatsu J, Konishi T, Inaki A, Kinuya S. J Nucl Cardiol 2021/12/14
  •  Safety and response after peptide receptor radionuclide therapy with 177 Lu-DOTATATE for neuroendocrine tumors in phase 1/2 prospective Japanese trial.  Kudo A, Tateishi U, Yoshimura R, Tsuchiya J, Yokoyama K, Takano S, Kobayashi N, Utsunomiya D, Hata M, Ichikawa Y, Tanabe M, Hosono M, Kinuya S. J Hepatobiliary Pancreat Sci 2021/12/14
  •  Synthesis and evaluation of radiogallium-labeled long-chain fatty acid derivatives as myocardial metabolic imaging agents.  Effendi N, Mishiro K, Wakabayashi H, Gabryel-Skrodzka M, Shiba K, Taki J, Jastrząb R, Kinuya S, Ogawa K. PLoS One 16 12 e0261226 2021/12/15
  •  Application of a tungsten apron for occupational radiation exposure in nursing care of children with neuroblastoma during 131I-meta-iodo-benzyl-guanidine therapy.  Taniguchi Y, Wakabayashi H, Yoneyama H, Chen Z, Morino K, Otosaki A, Yamada M, Inaki A, Kayano D, Kinuya S. Sci Rep 12 1 47 2022/01/07
  •  Development of Radiohalogenated Osimertinib Derivatives as Imaging Probes for Companion Diagnostics of Osimertinib.  Mishiro K, Nishii R, Sawazaki I, Sofuku T, Fuchigami T, Sudo H, Effendi N, Makino A, Kiyono Y, Shiba K, Taki J, Kinuya S, Ogawa K. J Med Chem. 2022/01/11
  •  Evaluation of skeletal muscle activity during foot training exercises using positron emission tomography Kanayama T, Nakase J, Mochizuki T, Asai K, Yoshimizu R, Kimura M, Kinuya S, Tsuchiya H. Sci Rep.  12 1 7076 2022/04/30
  •  Manual on the proper use of meta-[ 211 At] astato-benzylguanidine ([ 211 At] MABG) injections in clinical trials for targeted alpha therapy (1st edition) Ukon N, Higashi T, Hosono M, Kinuya S, Yamada T, Yanagida S, Namba M, Nakamura Y. Ann Nucl Med 36 8 695-709 2022/07/06
  •  Diagnosis of Parkinson syndrome and Lewy-body disease using 123 I-ioflupane images and a model with image features based on machine learning Nakajima K, Saito S, Chen Z, Komatsu J, Maruyama K, Shirasaki N, Watanabe S, Inaki A, Ono K, Kinuya S. Ann Nucl Med 2022/07/07
  •  I-131 metaiodobenzylguanidine therapy is a significant treatment option for pheochromocytoma and paraganglioma Zhang X, Wakabayashi H, Kayano D, Inaki A, Kinuya S. Nuklearmedizin 61 3 231-239 2022/06
  •  Prediction of multivessel coronary artery disease and candidates for stress-only imaging using multivariable models with myocardial perfusion imaging Kunita Y, Nakajima K, Nakata T, Kudo T, Kinuya S. Ann Nucl Med 36 7 674-683 2022/07
  •  Long-term outcomes and prognostic factors of patients with lung metastases from differentiated thyroid cancer after radioiodine therapy in Japan. Akatani N, Wakabayashi H, Kayano D, Inaki A, Takata A, Hiromasa T, Yamase T, Kunita Y, Watanabe S, Mori H, Saito S, Nakajima K, Kinuya S. Endocr J 70 3 315-322 2023
  •  An open-label, single-arm, multi-center, phase II clinical trial of single-dose [131I]meta-iodobenzylguanidine therapy for patients with refractory pheochromocytoma and paraganglioma Inaki A, Shiga T, Tsushima Y, Jinguji M, Wakabayashi H, Kayano D, Akatani N, Yamase T, Kunita Y, Watanabe S, Hiromasa T, Mori H, Hirata K, Watanabe S, Higuchi T, Tomonaga H, Kinuya S. Ann Nucl Med 36 3 267-278 2022/03/01
  •  Comparison of diagnostic performance of four software packages for phase dyssynchrony analysis in gated myocardial perfusion SPECT. Okuda K, Nakajima K, Matsuo S, Kashiwaya S, Yoneyama H, Shibutani T, Onoguchi M, Hashimoto M, Kinuya S. EJNMMI Res 2017
  •  Fundamental study of radiogallium-labeled aspartic acid peptides introducing octreotate derivatives. Ishizaki A, Mishiro K, Shiba K, Hanaoka H, Kinuya S, Odani A, Ogawa K. Ann Nucl Med 2019/03/01
  •  A case of frequent hypoglycemic attacks successfully controlled with capecitabine plus temozolomide and 177Lu-DOTATATE peptide receptor radionuclide therapy in a patient with recurrent pancreatic insulinoma Takeshi Terashima, Tatsuya Yamashita, Naoki Takemura, Anri Inaki, Akinori Shimizu, Kenichi Harada, Taro Yamashita, Seigo Kinuya, Keiji Hanada Clin J Gastroentherology 2023/06/20
  •  Synthesis and evaluation of a deltic guanidinium analogue of a cyclic RGD peptide.  Mishiro K, Ueno T, Wakabayashi H, Fukui M, Kinuya S, Ogawa K. Org Biomol Chem 2023/02/08
  •  Recent Advances in Radiopharmaceutical Theranostics of Pheochromocytoma and Paraganglioma Zhang X, Wakabayashi H, Hiromasa T, Kayano D, Kinuya S. Semin Nucl Med 2023/01/12
  •  Long-term outcomes and prognostic factors of patients with lung metastases from differentiated thyroid cancer after radioiodine therapy in Japan Akatani N, Wakabayashi H, Kayano D, Inaki A, Takata A, Hiromasa T, Yamase T, Kunita Y, Watanabe S, Mori H, Saito S, Nakajima K, Kinuya S. Endocr J 2022/12/24
  •  Prognostic value of olfactory nerve damage measured with thallium-based olfactory imaging in patients with idiopathic olfactory dysfunction Hideki Shiga, Junichi Taki, Okuda Koichi, Naoto Watanabe, Hisao Tonami, HIdeaki Nakagawa, Seigo Kinuya, Takaki Miwa Scientific Repoarts 7 3581 2017/06/15
  •  Validation of Left Ventricular Ejection Fraction with the IQ•SPECT System in Small-Heart Patients. Yoneyama H, Shibutani T, Konishi T, Mizutani A, Hashimoto R, Onoguchi M, Okuda K, Matsuo S, Nakajima K, Kinuya S. J Nucl Med Technol. 45 3 201-207 2017
  •  Phase II study of radium‑223 dichloride in Japanese patients with symptomatic castration‑resistant prostate cancer Nobuaki Matsubara, Satsohi Nagamori, Yoshiaki Wakumoto, Hirotsugu Uemura, Go Kimura, Akira Yokomizo,Hiroaki Kikukawa, Atsushi Mizokami, Takeo Kosaka, Naoya Masumori,Yoshihide Kawasaki, Junji Yonese,Yasutomo Nasu,Satoshi Fukasawa,Takayuki Sugiyama, Seigo Kinuya,Makoto Hosono,Iku Yamaguchi,Hirokazu Tsutsui,Hiroji Uemura Int J Clin Oncol 2017
  •  Bone scan index of the jaw: a new approach for evaluating early-stage anti-resorptive agents-related osteonecrosis. Watanabe S, Nakajima K, Mizokami A, Yaegashi H, Noguchi N, Kawashiri S, Inokuchi M, Kinuya S. Ann Nucl Med 31 3 201-210 2017
  •  Current status of radioactive iodine therapy for thyroid cancer SEIGO KINUYA 89 11 900-908 2017
  •  Complete remission of metastatic pheochromocytoma in 123I-metaiodobenzylguanidine scintigraphy after a single session of 131I-metaiodobenzylguanidine therapy: a case report. Sugino T, Ando R, Unno R, Iida K, Naiki T, Hamamoto S, Mizuno K, Okada A, Umemoto Y, Kawai N, Tozawa K, Hayashi Y, Inaki A, Kayano D, Kinuya S, Yasui T. BMC Res Notes 2017/12/19
  •  Quantification of Myocardial Perfusion Defect Size in Rats: Comparison between Quantitative Perfusion SPECT and Autoradiography. Wakabayashi H, Taki J, Inaki A, Hiromasa T, Okuda K, Shibutani T, Shiba K, Kinuya S. Mol Imaging Biol 2018/01/16
  •  Consideration for radioiodine therapy 90 5 314-315 2018
  •  Feasibility of High-dose Iodine-131-metaiodobenzylguanidine Therapy for High-risk Neuroblastoma Preceding Myeloablative Chemotherapy and Hematopoietic Stem Cell Transplantation: a Study Protocol  Raita Araki; Ryosei Nishimura; Anri Inaki; Hiroshi Wakabayashi; Yasuhito Imai; Yoshikazu Kuribayashi; Kenichi Yoshimura; Toshinori Murayama; Seigo Kinuya  Asia Oceania Journal of Nuclear Medcine and Biology 6 2 161-166 2018
  •  Three year follow up of a phase II study of radium-223 dichloride in Japanese patients with symptomatic castration-resistant prostate cancer and bone metastases Hirotsugu Uemura, Hiroji Uemura, Satsohi Nagamori, Yoshiaki Wakumoto, Go Kimura, Hiroaki Kikukawa, Akira Yokomizo, Atsushi Mizokami, Takeo Kosaka, Naoya Masumori, Yoshihide Kawasaki, Junji Yonese, Yasutomo Nasu, Satoshi Fukasawa, Takayuki Sugiyama, Seigo Kinuya, Makoto Hosono, Iku Yamaguchi, Takashi Akagawa, Nobuaki Matsubara International Journal of Clinical Oncology 2019
  •  Japanese Expert Panel Meeting on the Management of Prostate Cancer with Bone Metastases Shunji Takahashi . Seigo Kinuya . Norio Nonomura . Nobuo Shinohara . Kazuhiro Suzuki . Hiroyoshi Suzuki . Katsumasa Nakamura . Takefumi Satoh . Ukihide Tateishi . Toshiyuki Yoneda . Hiroyuki Horikoshi . Tsukasa Igawa . Takao Kamai . Mitsuru Koizumi . Takeo Kosaka . Nobuaki Matsubara . Hideaki Miyake . Atsushi Mizokami . Takashi Mizowaki . Naoki Nakamura . Masahiro Nozawa . Takeo Takahashi . Hiroji Uemura . Motohide Uemura . Akira Yokomizo . Mana Yoshimura . Yoshiyuki Kakehi Oncol Ther 6 2 157–171 2018
  •  Imaging modalities for drug-related osteonecrosis of the jaw (5), utility of bone scintigraphy and 18F-FDG PET/CT in early detection and risk assessment of medication-related osteonecrosis of the jaw (secondary publication) Satoru Watanabe, Kenichi Nakajima, Seigo Kinuya Japanese Dental Science Review 55 1 76-79 2019/03/29
  •  Activities for the Development of Targeted Radionuclide Therapy in Japan. Nucl Med Mol Imaging. 1 53 35-37 2019
  •  Postconditioning Accelerates Myocardial Inflammatory Resolution Demonstrated by 14C-Methionine Imaging and Attenuates Ventricular Remodeling After Ischemia and Reperfusion. Taki J, Inaki A, Wakabayashi H, Matsunari I, Imanaka-Yoshida K, Ogawa K, Hiroe M, Shiba K, Kinuya S. Circ J.  83 12 2520-2526 2019/11/25
  •  Impact of iterative reconstruction with resolution recovery in myocardial perfusion SPECT: phantom and clinical studies. Okuda K, Nakajima K, Yoneyama H, Shibutani T, Onoguchi M, Matsuo S, Hashimoto M, Kinuya S. Sci Rep 23 1 19618 2019/12
  •  High-dose 131I-metaiodobenzylguanidine therapy in patients with high-risk neuroblastoma in Japan Kayano D, Wakabayashi H, Nakajima K, Kuroda R, Watanabe S, Inaki A, Toratani A, Akatani N, Yamase T, Kunita Y, Hiromasa T, Takata A, Mori H, Saito S, Araki R, Taki J, Kinuya S. 2020/03/26
  •  Differences in 18F-FDG Uptake and Expression of Glucose Transporter Between 2 Distinct Subtypes of Mass-Forming Intrahepatic Cholangiocarcinomas Kazuto Kozaka , Satoshi Kobayashi , Hiroyuki Takamura, Yasunori Sato , Azusa Kitao , Dai Inoue , Norihide Yoneda, Hidehiro Tajima , Seigo Kinuya , Kenichi Harada, Tetsuo Ohta, Wataru Koda, Osamu Matsui, Toshifumi Gabata  Clin Nucl Med 45 6 e267-e273 2020/06/01
  •  Diagnostic Use of Post-therapy 131I-Meta-Iodobenzylguanidine Scintigraphy in Consolidation Therapy for Children with High-Risk Neuroblastoma Hiroshi Wakabayashi, Daiki Kayano, Anri Inaki, Raita Araki, Rie Kuroda, Norihito Akatani, Takafumi Yamase, Satoru Watanabe, Tomo Hiromasa, Yuji Kunita, Hiroshi Mori, Shintaro Saito, Yasuhiro Ikawa, Toshihiro Fujiki and Seigo Kinuya Diagnostics 10 663 2020/09/02
  •  High-dose 131 I-mIBG as consolidation therapy in pediatric patients with relapsed neuroblastoma and ganglioneuroblastoma: the Japanese experience Wakabayashi H, Kayano D, Inaki A, Araki R, Kuroda R, Ikawa Y, Fujiki T, Akatani N, Yamase T, Watanabe S, Hiromasa T, Kunita Y, Mori H, Saito S, Nishimura R, Wada T, Kinuya S. Ann Nucl Med 2020/08/29
  •  Real-world safety and effectiveness of radium-223 in Japanese patients with castration-resistant prostate cancer (CRPC) and bone metastasis: exploratory analysis, based on the results of post-marketing surveillance, according to prior chemotherapy status and in patients without concomitant use of second-generation androgen-receptor axis-targeted agents  Uemura H, Masumori N, Takahashi S, Hosono M, Kinuya S, Sunaya T, Horio T, Okayama Y, Kakehi Y. Int J Clin Oncol. 26 4 753-763 2021/02/11
  •  68Ga- and 211At-Labeled RGD Peptides for Radiotheranostics with Multiradionuclides Kazuma Ogawa, Hiroaki Echigo, Kenji Mishiro, Saki Hirata, Kohshin Washiyama, Yoji Kitamura, Kazuhiro Takahashi, Kazuhiro Shiba, and Seigo Kinuya Molecular Pharmaceutical 18 9 3553-3562 2021/08/18
  •  Development and evaluation of a theranostic probe with RGD peptide introduced platinum complex to enable tumor-specific accumulation Echigo H, Mishiro K, Munekane M, Fuchigami T, Kitamura Y, Kinuya S, Ogawa K. Bioorg Med Chem 70 116919 2022/07/05
  •  RGD Peptide-Conjugated Dodecaborate with the Ga−DOTA Complex: A Preliminary Study for the Development of Theranostic Agents for Boron Neutron Capture Therapy and Its Companion Diagnostics Kenji Mishiro, Sayaka Imai, Yuki Ematsu, Katsumi Hirose, Takeshi Fuchigami, Masayuki Munekane,Seigo Kinuya, and Kazuma Ogawa J Med Chem 65 24 16741-16753. 2022/12/22
  •  Synthesis and evaluation of radiolabeled porphyrin derivatives for cancer diagnoses and their nonradioactive counterparts for photodynamic therapy Ramzi NI, Mishiro K, Munekane M, Fuchigami T, Hu X, Jastrząb R, Kitamura Y, Kinuya S, Ogawa K. 13 12 1565-1574 2022/09/22
  •  Methods of calculating 123I-β-methyl-P-iodophenyl-pentadecanoic acid washout rates in triglyceride deposit cardiomyovasculopathy Chen Z, Nakajima K, Hirano KI, Kamiya T, Yoshida S, Saito S, Kinuya S. Ann Nucl Med 36 11 986-997 2022/11/01
  •  Safety and response after peptide receptor radionuclide therapy with 177 Lu-DOTATATE for neuroendocrine tumors in phase 1/2 prospective Japanese trial. Kudo A, Tateishi U, Yoshimura R, Tsuchiya J, Yokoyama K, Takano S, Kobayashi N, Utsunomiya D, Hata M, Ichikawa Y, Tanabe M, Hosono M, Kinuya S. J Hepatobiliary Pancreat Sci 29 4 487-499 2022/04/01
  •  Phase I/II clinical trial of high-dose [131I] meta-iodobenzylguanidine therapy for high-risk neuroblastoma preceding single myeloablative chemotherapy and haematopoietic stem cell transplantation. Kuroda R, Wakabayashi H, Araki R, Inaki A, Nishimura R, Ikawa Y, Yoshimura K, Murayama T, Imai Y, Funasaka T, Wada T, Kinuya S. Eur J Nucl Med Mol Imaging 49 5 1574-1583 2022/04/01
  •  Long-term outcomes and prognostic factors of patients with lung metastases from differentiated thyroid cancer after radioiodine therapy in Japan Akatani N, Wakabayashi H, Kayano D, Inaki A, Takata A, Hiromasa T, Yamase T, Kunita Y, Watanabe S, Mori H, Saito S, Nakajima K, Kinuya S. Endocr J 2022/12/24
  •  Prognostic factors for refractory pheochromocytoma and paraganglioma after 131I-metaiodobenzylguanidine therapy  Hiromasa T, Wakabayashi H, Kayano D, Inaki A, Watanabe S, Mori H, Akatani N, Yamase T, Kunita Y, Saito S, Kinuya S. Ann Nucl Med 36 1 61-69 2022/01/01
  •  Diagnosis of Parkinson syndrome and Lewy-body disease using 123 I-ioflupane images and a model with image features based on machine learning Nakajima K, Saito S, Chen Z, Komatsu J, Maruyama K, Shirasaki N, Watanabe S, Inaki A, Ono K, Kinuya S. Ann Nucl Med 36 8 765-776 2022/07/07
  •  Feasibility of 125I-RGD uptake as a marker of angiogenesis after myocardial infarction Yamase T, Taki J, Wakabayashi H, Inaki A, Hiromasa T, Mori H, Akatani N, Ogawa K, Shiba K, Kinuya S. Ann Nucl Med 36 3 235-243 2022/03/01
  •  Development of Radiohalogenated Osimertinib Derivatives as Imaging Probes for Companion Diagnostics of Osimertinib.  Mishiro K, Nishii R, Sawazaki I, Sofuku T, Fuchigami T, Sudo H, Effendi N, Makino A, Kiyono Y, Shiba K, Taki J, Kinuya S, Ogawa K. J Med Chem. 65 3 1835-1847 2022/01/11
  •  Artificial neural network retrained to detect myocardial ischemia using a Japanese multicenter database. Nakajima K, Okuda K, Watanabe S, Matsuo S, Kinuya S, Toth K, Edenbrandt L. Ann Nucl Med 32 5 303-310 2018
  •  Imaging Somatostatin Receptor Activity in Neuroendocrine-differentiated Prostate Cancer. Mori H, Nakajima K, Kadomoto S, Mizokami A, Ikeda H, Wakabayashi H, Kinuya S. Intern Med 2018
  •  Objective evaluation of cerebrovascular reactivity for acetazolamide predicts cerebral hyperperfusion after carotid artery stenting: Comparison with region of interest methods. Misaki K, Uchiyama N, Inaki A, Kinuya S, Nambu I, Kamide T, Mohri M, Hayashi Y, Nakada M. J Neuroradiol S0150-9861 17 30361-9 2018
  •  The Imaging and Dosimetry for Targeted Ra-223 Treatment for Metastatic Castration-Resistant Prostate Cancer. Matsuo S, Mizokami A, Wakabayashi H, Nakajima K, Kudo T and Kinuya S. Austin J Nucl Med Radiother 5 1 1024 2018
  •  Objective evaluation of cerebrovascular reactivity for acetazolamide predicts cerebral hyperperfusion after carotid artery stenting: Comparison with region of interest methods. Misaki K, Uchiyama N, Inaki A, Kinuya S, Nambu I, Kamide T, Mohri M, Hayashi Y, Nakada M. J Neuroradiol.  S0150-9861 17 30361-9 2018
  •  Is 123I-metaiodobenzylguanidine heart-to-mediastinum ratio dependent on age? From Japanese Society of Nuclear Medicine normal database Kenichi Nakajima, Koichi Okuda, Shinro Matsuo, Hiroshi Wakabayashi, Seigo Kinuya Ann Nucl Med 32 2018/01/15
  •  Update of diagnostic imaging for prostate cancer 1 2 75-81 2018
  •  Manual on the proper use of lutetium-177-labeled somatostatin analogue (Lu-177-DOTA-TATE) injectable in radionuclide therapy (2nd ed.). Hosono M, Ikebuchi H, Nakamura Y, Nakamura N, Yamada T, Yanagida S, Kitaoka A, Kojima K, Sugano H, Kinuya S, Inoue T, Hatazawa J. Ann Nucl Med 2018/01/15
  •  Comparison of Radioiodine- or Radiobromine-Labeled RGD Peptides between Direct and Indirect Labeling Methods. Ogawa K, Takeda T, Yokokawa M, Yu J, Makino A, Kiyono Y, Shiba K, Kinuya S, Odani A. Chem Pharm Bull (Tokyo) 66 6 651-659 2018
  •  Imaging Somatostatin Receptor Activity in Neuroendocrine-differentiated Prostate Cancer. Mori H, Nakajima K, Kadomoto S, Mizokami A, Ikeda H, Wakabayashi H, Kinuya S. Intern Med. 2018 Jun 6.  2018
  •  Activities for the development of targeted radionuclide therapy in Japan Seigo Kinuya Nuclear Medeicine and Molecular Imaging 2019
  •  Radiotheranostics Coupled between an At-211-Labeled RGD Peptide and the Corresponding Radioiodine-Labeled RGD Peptide Kazuma Ogawa, Takuya Takeda, Kenji Mishiro, Atsushi ToyoshiKazuma Ogawa*†‡ , Takuya Takeda‡, Kenji Mishiro† , Atsushi Toyoshima§, Kazuhiro Shiba∥, Takashi Yoshimuma, Kazuhiro Shiba, Takashi Yoshimura , Atsushi Shinohara, Seigo Kinuya, and Akira Odani ACS Omega 2019
  •  131I-MIBG therapy with WT-1 peptide for refractory neuroblastoma Minako Sugiyama Kinuya Seigo Yosuke Hosoya Akihiro Iguchi Atsushi Manabe Pediatrics International 2020/06/01
  •  Current Consensus on I-131 MIBG Therapy Kayano D, Kinuya S Nuclear Medicine and Molecular Imaging 52 1-12 2018
  •  Synthesis and Fundamental Evaluation of Radioiodinated Rociletinib (CO-1686) as a Probe to Lung Cancer with L858R/T790M Mutations of Epidermal Growth Factor Receptor (EGFR) Muammar Fawwaz, Kenji Mishiro, Ryuichi Nishii, Izumi Sawazaki, Kazuhiro Shiba, Seigo Kinuya and Kazuma Ogawa Molecules 25 12 2914 2020/06/24
  •  Decreasing undesirable absorbed radiation to the intestine after administration of radium-223 dichloride for treatment of bone metastases Kazuma Ogawa, Takuma Higashi, Kenji Mishiro, Hiroshi Wakabayashi, Kazuhiro Shiba, Akira Odani & Seigo Kinuya  Scientific Report 10 11917  2020/07/17
  •  Pharmacological intervention with angiotensin II and kininase inhibitor enhanced efficacy of radioimmunotherapy in human colon cancer xenografts. JOURNAL OF NUCLEAR MEDICINE 41 7 1244-1249 2000/07
  •  Anti-angiogenic therapy and radioimmunotherapy in colon cancer xenografts EUROPEAN JOURNAL OF NUCLEAR MEDICINE 28 9 1306-1312 2001/09
  •  New section in EJNMMI and Annals of Nuclear Medicine. Carrió I, Kinuya S. Ann Nucl Med.  30 9 593 2016
  •  Enhanced efficacy of radioimmunotherapy combined with systemic chemotherapy and local hyperthermia in xenograft model JAPANESE JOURNAL OF CANCER RESEARCH 91 5 573-578 2000/05
  •  Assessment of left ventricular systolic and diastolic function based on the edge detection method with myocardial ECG-gated SPET EUROPEAN JOURNAL OF NUCLEAR MEDICINE 28 10 1512-1516 2001/10
  •  Esophageal hypomotility in systemic sclerosis: close relationship with pulmonary involvement ANNALS OF NUCLEAR MEDICINE 15 2 97-101 2001/04
  •  A nuclear power plant accident in Fukushima: What should we do? Kinuya, Seigo Annals of Nuclear Medicine 26 2 113-114 2012/02/01 
  •  Bone scan index of the jaw: a new approach for evaluating early-stage anti-resorptive agents-related osteonecrosis. Okuda K, Nakajima K, Matsuo S, Kondo C, Sarai M, Horiguchi Y, Konishi T, Onoguchi M, Shimizu T, Kinuya S. Ann Nucl Med 2017
  •  Creation and characterization of normal myocardial perfusion imaging databases using the IQ·SPECT system. Okuda K, Nakajima K, Matsuo S, Kondo C, Sarai M, Horiguchi Y, Konishi T, Onoguchi M, Shimizu T, Kinuya S. J Nucl Cardiol 10.1007/s12350-016-0770-2 2017
  •  99mTc-tetrofosmin uptake in bone metastases from breast cancer ANNALS OF NUCLEAR MEDICINE 12 5 293-296 1998/10
  •  177Lu-EDTMP: A potential therapeutic bone agent NUCLEAR MEDICINE COMMUNICATIONS 19 6 587-591 1998/06
  •  Development of a myocardial phantom and analysis system toward the standardization of myocardial SPECT image across institutions. Shibutani T, Onoguchi M, Katafuchi T, Kinuya S. Ann Nucl Med 30 10 699-707 2016/12/01
  •  Clinical approach to renal study incidental to 99mTc-MDP bone scintigraphy ANNALS OF NUCLEAR MEDICINE 15 3 237-245 2001/06
  •  Early detection of x-ray CT negative recurrent lung cancer with Tl-201 SPECT CLINICAL NUCLEAR MEDICINE 22 3 196-197 1997/03
  •  Differential uptake of Tl-201 by small-cell lung cancer in a patient with pneumoconiosis-related pulmonary nodules CLINICAL NUCLEAR MEDICINE 24 9 687-690 1999/09
  •  Combination radioimmunotherapy with local hyperthermia: increased delivery of radioimmunoconjugate by vascular effect and its retention by increased antigen expression in colon cancer xenografts CANCER LETTERS 140 1-2 209-218 1999/01
  •  Experimental investigation of I-123 iodoamphetamine in the detection of lung cancer LUNG CANCER 25 1 1-6 1999/01
  •  Increased uptake of 99mTc-HL91 in tumor cells exposed to X-ray radiation ANNALS OF NUCLEAR MEDICINE 14 2 139-141 2000/02
  •  Forward cardiac output measurement with first-pass technique using 99mTc-labeled myocardial perfusion imaging agents JOURNAL OF NUCLEAR MEDICINE 40 11 1874-1881 1999/11
  •  Improved response of colon cancer xenografts to radioimmunotherapy with pentoxifylline treatment EUROPEAN JOURNAL OF NUCLEAR MEDICINE 28 6 750-755 2001/06
  •  Efficacy, toxicity and mode of interaction of combination radioimmunotherapy with 5-fluorouracil in colon cancer xenografts JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 125 11 630-636 1999/11
  •  Incidential detection of pulmonary infection during the evaluation of protein losing enteropathy with In-111 transferrin. CLINICAL NUCLEAR MEDICINE 22 6 297-398 1997/06
  •  Mallory-Weiss syndrome caused by radiation sickness of I-131 therapy for metastatic thyroid carcinoma JOURNAL OF NUCLEAR MEDICINE 38 11 1831 1997/11
  •  Methylxanthine sensitization of human colon cancer cells to 186Re-monoclonalantibody JOURNAL OF NUCLEAR MEDICINE 42 4 596-600 2001/04
  •  Optimal timing of administration of hyperthermia in combined radioimmunotherapy Cancer Biotherapy and Radiopharmceuticals 15 4 373-379 2000/04
  •  Preparation and in vivo characteristics of 99mTc-EDTMP - comparison with 99mTc-MDP Memoirs Health Scl Med Kanazawa Univ 23 2 989-995 1999/12
  •  Experimental radioimmunotherapy with 186Re-MAG3-A7 anti-colorectal cancer monoclonal antibody: comparison with 131I-counterpart ANNALS OF NUCLEAR MEDICINE 15 3 199-202 2001/06
  •  Production of 105Rh-EDTMP and its bone accumulation APPLIED RADIATION AND ISOTOPES 52 2 211-215 2000/02
  •  Reversible cerebral hypoperfusion observed with Tc-99m HMPAO SPECT in reversible dementia caused by hypothyroidism CLINICAL NUCLEAR MEDICINE 24 9 666-668 1999/06
  •  Radiotoxicity after strontium-89 therapy for bone metastases using the micronucleus assay JOURNAL OF NUCLEAR MEDICINE 39 12 2077-2079 1998/12
  •  Relationship between hemodynamic parapeters during exercise and cardiac function Memoirs Health Scl Med Kanazawa University 21 37-44 1997/10
  •  Radiotoxicity after iodine-131 therapy for thyroid cancer using the micronucleus assay JOURNAL OF NUCLEAR MEDICINE 39 3 436-4 1998/10
  •  Multiple myeloma evaluated with 201Tl scintigraphy compared with bone scintigraphy JOURNAL OF NUCLEAR MEDICINE 40 7 1138-1142 1999/07
  •  Preoperative assessment of residual hepatic function reserve using 99mTc-DTPA-galactosyl-human albumin dynamic SPECT JOURNAL OF NUCLEAR MEDICINE 40 10 1644-1651 1999/10
  •  Systemic-portal shunt in unilateral iliac vein stenosis. CLINICAL NUCLEAR MEDICINE 22 6 404-406 1997/06
  •  Survey of myeloblastoma with Ga-67 scan in a patient with acute leukemia CLINICAL NUCLEAR MEDICINE 22 6 434-437 1997/06
  •  Prevalence of deep vein thrombosis in the lower limbs and the pelvis and pulmonary embolism in patients with positive antiphospholipid antibodies ANNALS OF NUCLEAR MEDICINE 15 6 495-497 2001/12
  •  Changes of 99mTc-sestamibi uptake in P-glycoprotein expressing leukemia cells treated in vivo with antisense oligodeoxynucleotide complementary to mdr-1 mRNA Bai J, Yokoyama K, Shiba K, Mori H, Fukuoka M, Watanabe N, Shuke N, Michigishi T, Tonami N World Journal of Nuclear Medicine 5 2 115-118 2006/04
  •  99mTc-sestamibi to monitor treatment with antisense oligodeoxynucleotide complementary to MRP mRNA in human breast cancer cells Bai J, Shiba K, Yokoyama K, Mori H, Fukuoka M, Watanabe M, Shuke N, Michigishi T, Tonami N ANNALS OF NUCLEAR MEDICINE 20 1 29-34 2006/01
  •  Intraperitoneal radioimmunotherapy to treat early phase of peritoneal dissemination of human colon cancer cells in a murine model NUCLEAR MEDICINE COMMUNICATIONS 28 2007
  •  Scintigraphic detection of varicoceles in infertile men Memoirs Health Scl Med Kanazawa Univ 22 29-34 1998/10
  •  In Vivo Differences between Two Optical Isomers of Radioiodinated o-iodo-trans-decalinvesamicol for Use as a Radioligand for the Vesicular Acetylcholine Transporter. Uno I, Kozaka T, Miwa D, Kitamura Y, Azim MA, Ogawa K, Taki J, Kinuya S, Shiba K. PLoS One. 11 1 e0146719 2016
  •  Effects of the belt electrode skeletal muscle electrical stimulation system on lower extremity skeletal muscle activity: Evaluation using positron emission tomography. Numata H, Nakase J, Inaki A, Mochizuki T, Oshima T, Takata Y, Kinuya S, Tsuchiya H. J Orthop Sci 21 1 53-56 2016
  •  A case of double cancers with myocardial metastasis mimicking acute myocardial infarction both on an electrocardiogram and on Tc-99m-MIBI myocardial SPECT ANNALS OF NUCLEAR MEDICINE 15 4 381-385 2001/08
  •  Early response of tumour to radiotherapy should be assessed by both uptake and retention of single photon tracers: In vitro analysis with 201Tl chloride, 99Tcm-sestamibi and 99Tcm-tetrofosmin in human bladder cancer cells and human leucocytes NUCLEAR MEDICINE COMMUNICATIONS 20 6 581-588 1999/06
  •  Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers. Shiga H,Taki J,Washiyama K,Yamamoto J,Kinase S,Okuda K,Kinuya S,Watanabe N,Tonami H,Koshida K,Amano R,Furukawa M,Miwa T PLoS One 8 2 e57671 2013
  •  Changes in muscle activity after performing the FIFA 11+ programme part 2 for 4 weeks. Takata Y, Nakase J, Inaki A, Mochizuki T, Numata H, Oshima T, Kinuya S, Tsuchiya H. J Sports Sci 34 20 2011-2017 2016
  •  Reducing the small-heart effect in pediatric gated myocardial perfusion single-photon emission computed tomography. Yoneyama H, Nakajima K, Okuda K, Matsuo S, Onoguchi M, Kinuya S, Edenbrandt L. J Nucl Cardiol 2016
  •  Optimization of the filter parameters in (99m)Tc myocardial perfusion SPECT studies: the formulation of flowchart. Shibutani T, Onoguchi M, Yamada T, Kamida H, Kunishita K, Hayashi Y, Nakajima T, Kinuya S. Australas Phys Eng Sci Med 39 2 571-581 2016
  •  Innovative exercise device for the abdominal trunk muscles: An early validation study. Kato S, Murakami H, Inaki A, Mochizuki T, Demura S, Nakase J, Yoshioka K, Yokogawa N, Igarashi T, Takahashi N, Yonezawa N, Kinuya S, Tsuchiya H. PLoS One. 12 2 e0172934 2017
  •  Molecular Imaging for Personalized Medicine. Russell J, Tian J, Kinuya S, Shen B, Li XF. Biomed Res Int. 5170159 2016
  •  Evaluation of cytological radiation damage to lymphocytes after I-131 metaiodobenzylguanidine therapy by the cytokinesis-blocked micronucleus assay. Watanabe N, Yokoyama K, Kinuya S, Tonami H. Ann Nucl Med. 30 9 624-628 2016
  •  Short-period-induced hypertension could improve tumor-to-nontumor ratios of radiolabeled monoclonal antibody NUCLEAR MEDICINE AND BIOLOGY 24 6 547-551 1997/06
  •  Technetium-99m-Tetrofosmin Would Be a Substrate for Multidrug Resistance-associated Protein (MRP): Comparison between a Leukemia Cell Line with High MRP Gene Expression and Its Parental Cell Line Cancer Biotherapy and Radiopharmceuticals 16 1 17-24 2001/02
  •  Evaluation of the olfactory nerve transport function by SPECT-MRI fusion image with nasal thallium-201 administration. Shiga H,Taki J,Yamada M,Washiyama K,Amano R,Matsuura Y,Matsui O,Tatsutomi S,Yagi S,Tsuchida A,Yoshizaki T,Furukawa M,Kinuya S,Miwa T Mol Imaging Biol 13 6 1262-6 2011
  •  Comparison of phase dyssynchrony analysis using gated myocardial perfusion imaging with four software programs: Based on the Japanese Society of Nuclear Medicine working group normal database. Nakajima K, Okuda K, Matsuo S, Kiso K, Kinuya S, Garcia EV. J Nucl Cardiol. 2016
  •  Diagnosis and treatment of bone metastasis: comprehensive guideline of the Japanese Society of Medical Oncology, Japanese Orthopedic Association, Japanese Urological Association, and Japanese Society for Radiation Oncology. Shibata H, Kato S, Sekine I, Abe K, Araki N, Iguchi H, Izumi T, Inaba Y, Osaka I, Kato S, Kawai A, Kinuya S, Kodaira M, Kobayashi E, Kobayashi T, Sato J, Shinohara N, Takahashi S, Takamatsu Y, Takayama K, Takayama K, Tateishi U, Nagakura H, Hosaka M, Morioka H, Moriya T, Yuasa T, Yurikusa T, Yomiya K, Yoshida M. ESMO Open 1 2 e000037 2016
  •  Thallium-201 scintigraphy for the assessment of long-term prognosis in patients with osteosarcoma. Inaki A,Taki J,Wakabayashi H,Sumiya H,Zen Y,Tsuchiya H,Kinuya S Ann Nucl Med 26 7 545-50 2012
  •  Whole Body Muscle Activity during the FIFA 11+ Program Evaluated by Positron Emission Tomography. Nakase J,Inaki A,Mochizuki T,Toratani T,Kosaka M,Ohashi Y,Taki J,Yahata T,Kinuya S,Tsuchiya H PLoS One 8 9 e73898 2013
  •  Adrenal mass and renal vessels mimicking intestinal bleeding in Tc-99m red blood cell scintigraphy CLINICAL NUCLEAR MEDICINE 22 11 785-786 1997/11
  •  Persistent distension and enhanced diffusive extravasation of tumor vessels improved uniform tumor targeting of radioimmunoconjugate in mice administered with angiotensin II and kininase inhibitor ONCOLOGY RESEARCH 10 11-12 551-559 1998/11
  •  Rhenium-186-mercaptoacetyltriglycine Labeled Monoclonal Antibody for Radioimmunotherapy: In vitro Assessment, in vivo Kinetics and Dosimetry in Tumor-bearing Nude Mice JAPANESE JOURNAL OF CANCER RESEARCH 89 8 870-878 1998/08
  •  Radionuclide cisternography in intracranical hypotension syndrome ANNALS OF NUCLEAR MEDICINE 16 1 75 2002/01
  •  Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT JOURNAL OF NUCLEAR MEDICINE 44 3 475-482 2003/03
  •  Hypoxia as a factor for Ga-67 accumulation in tumor cells NUCLEAR MEDICINE COMMUNICATIONS 25 1 49-53 2004/01
  •   Limitations of 99mTc-tetrofosmin in assessing reversal effects of verapamil on multi-drug resistance associated protein 1 (MRP1) function. NUCLEAR MEDICINE COMMUNICATIONS 25 7 585-589 2004/07
  •  Hypoxia-induced alteration of tracer accumulation in cultured cancer cells and xenografts in mice EUROPEAN JOURNAL OF NUCLEAR MEDICINE 29 8 1006 2002/08
  •  Role of brain perfusion single-photon emission tomography in traumatic head injury NUCLEAR MEDICINE COMMUNICATIONS 25 4 333-337 2004/04
  •  Intense 201Tl uptake in giant-cell tumour of bone NUCLEAR MEDICINE COMMUNICATIONS 23 8 595 2002/08
  •  Preliminary evaluation of image reconstruction by ordered-subset expectation maximiZation in thallium-201 lung scintigraphy ANNALS OF NUCLEAR MEDICINE 17 7 619-624 2003/10
  •  Locoregional radioimmunotherapy with 186Re-labeled monoclonal antibody in treating small peritoneal carcinomatosis of colon cancer in mice in comparison with 131I-counterpart CANCER LETTERS 219 1 41-48 2005/01
  •  227Th-EDTMP: a potential therapeutic agent for bone metastasis NUCLEAR MEDICINE AND BIOLOGY 31 9 901-908 2004/09
  •  Brown adipose tissue: evaluation with 201Tl and 99mTc-sestamibi dual-tracer SPECT ANNALS OF NUCLEAR MEDICINE 18 6 547-549 2004/12
  •  Cooperative effect of radioimmunotherapy and antiangiogenic therapy with thalidomide in human cancer xenografts JOURNAL OF NUCLEAR MEDICINE 43 8 1084 2002/08
  •  Thallium-201 SPECT with triple-headed gamma camera for differential diagnosis of small plumonary nodular lesion 20 mm in diameter of smaller ANNALS OF NUCLEAR MEDICINE 14 2 91-95 2000/04
  •  Statistical parametric mapping in brain single photon computed emission tomography after carbon monoxide intoxication NUCLEAR MEDICINE COMMUNICATIONS 23 4 355 2002/04
  •  Radioimmunotherapy with 186Re-labeled monoclonal antibody to treat liver metastases of colon cancer cells in nude mice CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 17 6 681 2002/12
  •  A new method for measuring dynamic change of tracer distribution using dynamic single photon emission tomography with a slip-ring rotational gamma camera NUCLEAR MEDICINE COMMUNICATIONS 23 11 1115 2002/11
  •  Benefits of combined radioimmunotherapy and anti-angiogenic therapy in a liver metastasis model of human colon cancer cells EUROPEAN JOURNAL OF NUCLEAR MEDICINE 29 12 1669 2002/12
  •  Anti-angiogenic therapy and radioimmuhnotherapy in colon cancer xenografts EUROPEAN JOURNAL OF NUCLEAR MEDICINE 28 9 1306 2001/09
  •  Differentiation of soft tissue hemangioma by 201Tl scintigraphy NUCLEAR MEDICINE COMMUNICATIONS 24 2 327-330 2003/02
  •  Intraperitoneal radioimmunotherapy in treating peritoneal carcinomatosis of colon cancer in mice compared with systemic radioimmunotherapy JAPANESE JOURNAL OF CANCER RESEARCH 94 7 650-654 2003/07
  •  Estimation of fractional liver uptake and blood retention of 99mTc-DTPA-galactosyl human serum albumin NUCLEAR MEDICINE COMMUNICATIONS 24 4 503-511 2003/04
  •  Evaluation of left and right ventricular functional parameters with automatic edge detection program of ECG gated blood SPET NUCLEAR MEDICINE COMMUNICATIONS 24 4 559-563 2003/04
  •  Visualization of bone structure with Tc-99m MIBI in a patient on hemodyalysis. CLINICAL NUCLEAR MEDICINE 22 5 331-332 1997/05
  •  Improved survival of mice bearing liver metastases of colon cancer cells treated with combination of radioimmunotherapy and antiangiogenic therapy EUROPEAN JOURNAL OF NUCLEAR MEDICINE 31 7 981-985 2004/07
  •  Thymic lesions in patients with myasthenia gravis: characterization with thallium 201 schintigraphy RADIOLOGY 221 1 201-206 2001/10
  •  Prognostic value of Tc-99m-MIBI performed during middle course of preoperative chemotherapy in patients with malignant bone and soft-tissue tumors. Wakabayashi H,Taki J,Inaki A,Sumiya H,Zen Y,Tsuchiya H,Kinuya S Clin Nucl Med 37 1 1-8
  •  Improvement of the (99m)Tc-ECD brain uptake ratio (BUR) method for measurement of cerebral blood flow. Ito S,Takaki A,Inoue S,Tomiguchi S,Shiraishi S,Akiyama Y,Sasaki T,Odajima S,Teraoka S,Hosoya T,Soma T,Miyazaki Y,Kinuya S,Yamashita Y Ann Nucl Med 26 4 351-8
  •  Thyroid remnant ablation using 1,110 MBq of I-131 after total thyroidectomy: regulatory considerations on release of patients after unsealed radioiodine therapy. Kusakabe K,Yokoyama K,Ito K,Shibuya H,Kinuya S,Ito M,Higashi T,Togawa T,Koizumi K,Yoshimura M,Uchiyama M,Okamoto T,Kanaya S,Kanaya K,Yoneyama T,Ikebuchi H,Yanagida S,Shibata K,Segawa K,Yamamoto A Ann Nucl Med 26 4 370-8
  •  Standardization of metaiodobenzylguanidine heart to mediastinum ratio using a calibration phantom: effects of correction on normal databases and a multicentre study. Nakajima K,Okuda K,Matsuo S,Yoshita M,Taki J,Yamada M,Kinuya S Eur J Nucl Med Mol Imaging 39 1 113-9
  •  Assessment of doxorubicin cardiac toxicity using gated ⁹⁹mTc-hexakis-2-methoxyisobutylisonitrile myocardial single photon emission computed tomography: wall thickening and motion abnormalities can be an early sign of cardiac involvement. Wakabayashi H,Taki J,Inaki A,Sumiya H,Tsuchiya H,Kinuya S Circ J 76 5 1190-6
  •  Radioactive iodine (131I) therapy for differentiated thyroid cancer in Japan: current issues with historical review and future perspective. Higashi T,Kudo T,Kinuya S Ann Nucl Med 26 2 99-112
  •  A nuclear power plant accident in Fukushima: what should we do? Ann Nucl Med 26 2 113-4
  •  Thallium-201 scintigraphy for the assessment of long-term prognosis in patients with osteosarcoma. Inaki A,Taki J,Wakabayashi H,Sumiya H,Zen Y,Tsuchiya H,Kinuya S Ann Nucl Med 26 7 545-50
  •  I-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastoma. Sato Y,Kurosawa H,Fukushima K,Okuya M,Hagisawa S,Sugita K,Arisaka O,Inaki A,Wakabayashi H,Nakamura A,Fukuoka M,Kayano D,Kinuya S Ital J Pediatr 38 53
  •  Optimization of iterative reconstruction parameters with attenuation correction, scatter correction and resolution recovery in myocardial perfusion SPECT/CT. Okuda K,Nakajima K,Yamada M,Wakabayashi H,Ichikawa H,Arai H,Matsuo S,Taki J,Hashimoto M,Kinuya S Ann Nucl Med
  •  Bone scintigraphy as a new imaging biomarker: the relationship between bone scan index and bone metabolic markers in prostate cancer patients with bone metastases. Wakabayashi H,Nakajima K,Mizokami A,Namiki M,Inaki A,Taki J,Kinuya S Ann Nucl Med 27 9 802-7
  •  [Targeted radionuclide therapy - where should we go ?]. Gan To Kagaku Ryoho 40 2 133-8
  •  Sensitive immunodetection of radiotoxicity after iodine-131 therapy for thyroid cancer using γ-H2AX foci of DNA damage in lymphocytes. Doai M,Watanabe N,Takahashi T,Taniguchi M,Tonami H,Iwabuchi K,Kayano D,Fukuoka M,Kinuya S Ann Nucl Med 27 3 233-8
  •  Improved Detection of Sentinel Lymph Nodes in SPECT/CT Images Acquired Using a Low- to Medium-Energy General-Purpose Collimator. Yoneyama H,Tsushima H,Kobayashi M,Onoguchi M,Nakajima K,Kinuya S Clin Nucl Med
  •  Prototype imaging protocols for monitoring the efficacy of iodine-131 ablation in differentiated thyroid cancer. Kobayashi M,Wakabayashi H,Kojima H,Konishi T,Okuda K,Yoneyama H,Kayano D,Tobisaka M,Tsushima H,Onoguchi M,Kawai K,Kinuya S Hell J Nucl Med 16 3 175-80
  •  Improved quantification of small hearts for gated myocardial perfusion imaging. Nakajima K,Okuda K,Nyström K,Richter J,Minarik D,Wakabayashi H,Matsuo S,Kinuya S,Edenbrandt L Eur J Nucl Med Mol Imaging 40 8 1163-70
  •  Prognostic values of initial responses to low-dose (131)I-MIBG therapy in patients with malignant pheochromocytoma and paraganglioma. Wakabayashi H,Taki J,Inaki A,Nakamura A,Kayano D,Fukuoka M,Matsuo S,Nakajima K,Kinuya S Ann Nucl Med 27 9 839-46
  •  14C-Methionine uptake as a potential marker of inflammatory processes after myocardial ischemia and reperfusion. Taki J,Wakabayashi H,Inaki A,Imanaka-Yoshida K,Hiroe M,Ogawa K,Morooka M,Kubota K,Shiba K,Yoshida T,Kinuya S J Nucl Med 54 3 431-6
  •  Semi-automated algorithm for calculating heart-to-mediastinum ratio in cardiac Iodine-123 MIBG imaging. Okuda K,Nakajima K,Hosoya T,Ishikawa T,Konishi T,Matsubara K,Matsuo S,Kinuya S J Nucl Cardiol 18 1 82-9
  •  Esophageal transit study using a sliding sum image: application to patients with probable and definite systemic sclerosis. Nakajima K,Hasegawa M,Inaki A,Wakabayashi H,Hosoya T,Takehara K,Kinuya S Ann Nucl Med 25 5 325-31
  •  Comparison of diagnostic value of I-123 MIBG and high-dose I-131 MIBG scintigraphy including incremental value of SPECT/CT over planar image in patients with malignant pheochromocytoma/paraganglioma and neuroblastoma. Fukuoka M,Taki J,Mochizuki T,Kinuya S Clin Nucl Med 36 1 1-7
  •  Quantification of myocardial perfusion SPECT using freeware package (cardioBull). Okuda K,Nakajima K,Hosoya T,Ishikawa T,Matsuo S,Kawano M,Taki J,Kinuya S Ann Nucl Med 25 8 571-9
  •  Low-dose (123)I-metaiodobenzylguanidine diagnostic scan is inferior to (131)I-metaiodobenzylguanidine posttreatment scan in detection of malignant pheochromocytoma and paraganglioma. Kayano D,Taki J,Fukuoka M,Wakabayashi H,Inaki A,Nakamura A,Kinuya S Nucl Med Commun 32 10 941-6
  •  Cause of apical thinning on attenuation-corrected myocardial perfusion SPECT. Okuda K,Nakajima K,Matsuo S,Wakabayashi H,Taki J,Kinuya S Nucl Med Commun 32 11 1033-9
  •  Tc-99m human serum albumin lymphoscintigraphy with SPECT/CT in chylothorax. Kayano D,Taki J,Wakabayashi H,Kinuya S Clin Nucl Med 36 11 1056-7
  •  Double-phase (131)I whole body scan and (131)I SPECT-CT images in patients with differentiated thyroid cancer: their effectiveness for accurate identification. Wakabayashi H,Nakajima K,Fukuoka M,Inaki A,Nakamura A,Kayano D,Kinuya S Ann Nucl Med 25 9 609-15
  •  The relationship between stress-induced myocardial ischemia and coronary artery atherosclerosis measured by hybrid SPECT/CT camera. Matsuo S,Nakajima K,Okuda K,Kinuya S Ann Nucl Med 25 9 650-6
  •  Standardization of metaiodobenzylguanidine heart to mediastinum ratio using a calibration phantom: effects of correction on normal databases and a multicentre study. Nakajima K,Okuda K,Matsuo S,Yoshita M,Taki J,Yamada M,Kinuya S Eur J Nucl Med Mol Imaging 39 1 113-9
  •  Sensitive immunodetection of radiotoxicity after iodine-131 therapy for thyroid cancer using γ-H2AX foci of DNA damage in lymphocytes. Doai M,Watanabe N,Takahashi T,Taniguchi M,Tonami H,Iwabuchi K,Kayano D,Fukuoka M,Kinuya S Ann Nucl Med 27 3 233-8
  •  A nuclear power plant accident in Fukushima: what should we do? Ann Nucl Med 26 2 113-4
  •  I-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastoma. Sato Y,Kurosawa H,Fukushima K,Okuya M,Hagisawa S,Sugita K,Arisaka O,Inaki A,Wakabayashi H,Nakamura A,Fukuoka M,Kayano D,Kinuya S Int J Med Sci 38 53
  •  Improved quantification of small hearts for gated myocardial perfusion imaging. Nakajima K,Okuda K,Nyström K,Richter J,Minarik D,Wakabayashi H,Matsuo S,Kinuya S,Edenbrandt L Eur J Nucl Med Mol Imaging 40 8 1163-70
  •  Assessment of doxorubicin cardiac toxicity using gated ⁹⁹mTc-hexakis-2-methoxyisobutylisonitrile myocardial single photon emission computed tomography: wall thickening and motion abnormalities can be an early sign of cardiac involvement. Wakabayashi H,Taki J,Inaki A,Sumiya H,Tsuchiya H,Kinuya S Circ J 76 5 1190-6
  •  Prognostic value of Tc-99m-MIBI performed during middle course of preoperative chemotherapy in patients with malignant bone and soft-tissue tumors. Wakabayashi H,Taki J,Inaki A,Sumiya H,Zen Y,Tsuchiya H,Kinuya S Clin Nucl Med 37 1 1-8
  •  Improved Detection of Sentinel Lymph Nodes in SPECT/CT Images Acquired Using a Low- to Medium-Energy General-Purpose Collimator. Yoneyama H,Tsushima H,Kobayashi M,Onoguchi M,Nakajima K,Kinuya S Clin Nucl Med
  •  Thyroid remnant ablation using 1,110 MBq of I-131 after total thyroidectomy: regulatory considerations on release of patients after unsealed radioiodine therapy. Kusakabe K,Yokoyama K,Ito K,Shibuya H,Kinuya S,Ito M,Higashi T,Togawa T,Koizumi K,Yoshimura M,Uchiyama M,Okamoto T,Kanaya S,Kanaya K,Yoneyama T,Ikebuchi H,Yanagida S,Shibata K,Segawa K,Yamamoto A Ann Nucl Med 26 4 370-8
  •  Prognostic values of initial responses to low-dose 131I-MIBG therapy in patients with malignant pheochromocytoma and paraganglioma. Wakabayashi H,Taki J,Inaki A,Nakamura A,Kayano D,Fukuoka M,Matsuo S,Nakajima K,Kinuya S Ann Nucl Med
  •  Bone scintigraphy as a new imaging biomarker: the relationship between bone scan index and bone metabolic markers in prostate cancer patients with bone metastases. Wakabayashi H,Nakajima K,Mizokami A,Namiki M,Inaki A,Taki J,Kinuya S Ann Nucl Med
  •  [Targeted radionuclide therapy - where should we go ?]. Gan To Kagaku Ryoho 40 2 133-8
  •  14C-Methionine uptake as a potential marker of inflammatory processes after myocardial ischemia and reperfusion. Taki J,Wakabayashi H,Inaki A,Imanaka-Yoshida K,Hiroe M,Ogawa K,Morooka M,Kubota K,Shiba K,Yoshida T,Kinuya S J Nucl Med 54 3 431-6
  •  Time course of discordant BMIPP and thallium uptake after ischemia and reperfusion in a rat model. Higuchi T,Taki J,Nakajima K,Kinuya S,Namura M,Tonami N J Nucl Med 46 1 172-5
  •  Anti-angiogenic therapy and chemotherapy affect 99mTc sestamibi and 99mTc-HL91 accumulation differently in tumour xenografts. Kinuya S,Yokoyama K,Fukuoka M,Mori H,Shiba K,Watanabe N,Shuke N,Michigishi T,Tonami N Nucl Med Commun 26 12 1067-73
  •  Characterization of cartilaginous tumors with 201Tl scintigraphy. Higuchi T,Taki J,Sumiya H,Kinuya S,Nakajima K,Namura M,Tonami N Ann Nucl Med 19 2 95-9
  •  Sonographically guided core biopsy of the salivary gland masses: safety and efficacy. Taki S,Yamamoto T,Kawai A,Terahata S,Kinuya K,Tonami H Clin Imaging 29 3 189-94
  •  Locoreginal radioimmunotherapy with 186Re-labeled monoclonal antibody in treating small peritoneal carcinomatosis of colon cancer in mice in comparison with 131I-counterpart. Kinuya S,Yokoyama K,Izumo M,Sorita T,Obata T,Mori H,Shiba K,Watanabe N,Shuke N,Michigishi T,Tonami N Cancer Lett 219 1 41-8
  •  Tc-99m MAA SPECT in pectus excavatum: assessment of perfusion volume changes after correction by the Nuss procedure. Kinuya K,Ueno T,Kobayashi T,Tuji T,Yamamoto Y,Kinuya S Clin Nucl Med 30 12 779-82
  •  A simple and rapid radiochemical choline acetyltransferase (ChAT) assay screening test. Shiba K,Ogawa K,Kinuya S,Yajima K,Mori H J Neurosci Methods 157 1 98-102
  •  Binding with serum components favorably affects cellular uptake of 111In-oligonucleotide in a leukemia cell line. Bai J,Kinuya S,Shiba K,Michigishi T,Tonami N Cancer Biother Radiopharm 21 1 34-40
  •  99mTc-sestamibi to monitor treatment with antisense oligodeoxynucleotide complementary to MRP mRNA in human breast cancer cells. Kinuya S,Bai J,Shiba K,Yokoyama K,Mori H,Fukuoka M,Watanabe N,Shuke N,Michigishi T,Tonami N Ann Nucl Med 20 1 29-34
  •  Radioiodinated VEGF to image tumor angiogenesis in a LS180 tumor xenograft model. Yoshimoto M,Kinuya S,Kawashima A,Nishii R,Yokoyama K,Kawai K Nucl Med Biol 33 8 963-9
  •  Respiratory distress caused by radioiodine therapy in patients with differentiated thyroid cancer. Kinuya S,Yokoyama K,Michigishi T,Tonami N Ann Nucl Med 20 7 499-502
  •  Changes in the levels of CD4+ and CD8+ T-lymphocytes after strontium-89 chloride therapy for painful bone metastases in patients correlate with treatment efficacy. Li Y,Li XF,Ma Y,Fang N,Russell J,Ma D,Sun X,Han X,Yang H,Kinuya S Cancer Biother Radiopharm 22 3 367-73
  •  Correction of iodine-123-labeled meta-iodobenzylguanidine uptake with multi-window methods for standardization of the heart-to-mediastinum ratio. Nakajima K,Matsubara K,Ishikawa T,Motomura N,Maeda R,Akhter N,Okuda K,Taki J,Kinuya S J Nucl Cardiol 14 6 843-51
  •  In vivo characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino] cyclohexanol as a potential sigma-1 receptor imaging agent. Akhter N,Shiba K,Ogawa K,Kinuya S,Nakajima K,Mori H Nucl Med Biol 34 6 697-702
  •  Effect of postconditioning on myocardial 99mTc-annexin-V uptake: comparison with ischemic preconditioning and caspase inhibitor treatment. Taki J,Higuchi T,Kawashima A,Fukuoka M,Kayano D,Tait JF,Matsunari I,Nakajima K,Kinuya S,Strauss HW J Nucl Med 48 8 1301-7
  •  Intraperitoneal radioimmunotherapy to treat the early phase of peritoneal dissemination of human colon cancer cells in a murine model. Kinuya S,Yokoyama K,Fukuoka M,Hiramatsu T,Mori H,Shiba K,Watanabe N,Shuke N,Michigishi T,Tonami N Nucl Med Commun 28 2 129-33
  •  Therapeutic effects of a 186Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model. Ogawa K,Mukai T,Asano D,Kawashima H,Kinuya S,Shiba K,Hashimoto K,Mori H,Saji H J Nucl Med 48 1 122-7
  •  Therapeutic effects of a 186Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model. Ogawa K,Mukai T,Asano D,Kawashima H,Kinuya S,Shiba K,Hashimoto K,Mori H,Saji H J Nucl Med 48 1 122-7
  •  Intraperitoneal radioimmunotherapy to treat the early phase of peritoneal dissemination of human colon cancer cells in a murine model. Kinuya S,Yokoyama K,Fukuoka M,Hiramatsu T,Mori H,Shiba K,Watanabe N,Shuke N,Michigishi T,Tonami N Nucl Med Commun 28 2 129-33
  •  In vivo characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino] cyclohexanol as a potential sigma-1 receptor imaging agent. Akhter N,Shiba K,Ogawa K,Kinuya S,Nakajima K,Mori H Nucl Med Biol 34 6 697-702
  •  Changes in the levels of CD4+ and CD8+ T-lymphocytes after strontium-89 chloride therapy for painful bone metastases in patients correlate with treatment efficacy. Li Y,Li XF,Ma Y,Fang N,Russell J,Ma D,Sun X,Han X,Yang H,Kinuya S Cancer Biother Radiopharm 22 3 367-73
  •  Correction of iodine-123-labeled meta-iodobenzylguanidine uptake with multi-window methods for standardization of the heart-to-mediastinum ratio. Nakajima K,Matsubara K,Ishikawa T,Motomura N,Maeda R,Akhter N,Okuda K,Taki J,Kinuya S J Nucl Cardiol 14 6 843-51
  •  Effect of postconditioning on myocardial 99mTc-annexin-V uptake: comparison with ischemic preconditioning and caspase inhibitor treatment. Taki J,Higuchi T,Kawashima A,Fukuoka M,Kayano D,Tait JF,Matsunari I,Nakajima K,Kinuya S,Strauss HW J Nucl Med 48 8 1301-7
  •  Therapeutic effects of a 186Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model. Ogawa K,Mukai T,Asano D,Kawashima H,Kinuya S,Shiba K,Hashimoto K,Mori H,Saji H J Nucl Med 48 1 122-7
  •  Intraperitoneal radioimmunotherapy to treat the early phase of peritoneal dissemination of human colon cancer cells in a murine model. Kinuya S,Yokoyama K,Fukuoka M,Hiramatsu T,Mori H,Shiba K,Watanabe N,Shuke N,Michigishi T,Tonami N Nucl Med Commun 28 2 129-33
  •  In vivo characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino] cyclohexanol as a potential sigma-1 receptor imaging agent. Akhter N,Shiba K,Ogawa K,Kinuya S,Nakajima K,Mori H Nucl Med Biol 34 6 697-702
  •  Changes in the levels of CD4+ and CD8+ T-lymphocytes after strontium-89 chloride therapy for painful bone metastases in patients correlate with treatment efficacy. Li Y,Li XF,Ma Y,Fang N,Russell J,Ma D,Sun X,Han X,Yang H,Kinuya S Cancer Biother Radiopharm 22 3 367-73
  •  Effect of postconditioning on myocardial 99mTc-annexin-V uptake: comparison with ischemic preconditioning and caspase inhibitor treatment. Taki J,Higuchi T,Kawashima A,Fukuoka M,Kayano D,Tait JF,Matsunari I,Nakajima K,Kinuya S,Strauss HW J Nucl Med 48 8 1301-7
  •  Correction of iodine-123-labeled meta-iodobenzylguanidine uptake with multi-window methods for standardization of the heart-to-mediastinum ratio. Nakajima K,Matsubara K,Ishikawa T,Motomura N,Maeda R,Akhter N,Okuda K,Taki J,Kinuya S J Nucl Cardiol 14 6 843-51
  •  Regional wall thickening in gated myocardial perfusion SPECT in a Japanese population: effect of sex, radiotracer, rotation angles and frame rates. Akhter N,Nakajima K,Okuda K,Matsuo S,Yoneyama T,Taki J,Kinuya S Eur J Nucl Med Mol Imaging 35 9 1608-15
  •  The sentinel node concept in prostate cancer: Present reality and future prospects. Egawa M,Fukuda M,Takashima H,Misaki T,Kinuya K,Terahata S Indian J Urol 24 4 451-6
  •  Cardiac scintigraphic findings of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes: A case report. Matsuo S,Nakajima K,Kinuya S,Sato Y,Matsumoto N,Horie M Exp Clin Cardiol 13 2 93-5
  •  Iodine-123-MIBG sympathetic imaging in Lewy-body diseases and related movement disorders. Nakajima K,Yoshita M,Matsuo S,Taki J,Kinuya S Q J Nucl Med Mol Imaging 52 4 378-87
  •  Localization of metastases from malignant pheochromocytoma in patients undergoing 131I-MIBG therapy with manually fused 123I-MIBG SPECT and CT images. Kizu H,Takayama T,Tsushima H,Noguchi A,Nakajima K,Onoguchi M,Kinuya S J Nucl Med Technol 36 4 186-8
  •  Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegenerative diseases. Shiba K,Torashima T,Hirai H,Ogawa K,Akhter N,Nakajima K,Kinuya S,Mori H J Cereb Blood Flow Metab 29 2 434-40
  •  [Assessment for the image interpretation of 111In-ibritumomab tiuxetan in the phase II study of 90Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma]. Oriuchi N,Koizumi K,Koizumi M,Terui S,Yamaura H,Imai Y,Kaneta T,Nawano S,Kubo A,Nishimura T,Kinuya S,Tobinai K,Endo K Kaku Igaku 45 2 99-113
  •  Standardization of the heart-to-mediastinum ratio of 123I-labelled-metaiodobenzylguanidine uptake using the dual energy window method: feasibility of correction with different camera-collimator combinations. Matsuo S,Nakajima K,Okuda K,Kawano M,Ishikawa T,Hosoya T,Taki J,Kinuya S Eur J Nucl Med Mol Imaging 36 4 560-6
  •  [Guideline draft of appropriate use of 131I-MIBG for internal radiotherapy of neuroendocrine tumors]. Nakajo M,Yoshinaga K,Oriuchi N,Kinuya S,Yokoyama K,Yamaguchi T,Drafting Committee for Guideline of Internal Radiotherapy with 131I-MIBG,Japanese Society of Nuclear Medicine in Oncology and Immunology,Japanese Society of Nuclear Medicine Kaku Igaku 45 1 suppl 1-40
  •  A change of in vivo characteristics depending on specific activity of radioiodinated (+)-2-[4-(4-iodophenyl)piperidino]cyclohexanol [(+)-pIV] as a ligand for sigma receptor imaging. Akhter N,Shiba K,Ogawa K,Tsuji S,Kinuya S,Nakajima K,Mori H Nucl Med Biol 35 1 29-34
  •  [Recent topics in targeted radiotherapy: metastron, zevalin and thyroid cancer]. Nihon Hoshasen Gijutsu Gakkai Zasshi 65 5 659-67
  •  Preparation and evaluation of 186/188Re-labeled antibody (A7) for radioimmunotherapy with rhenium(I) tricarbonyl core as a chelate site. Ogawa K,Kawashima H,Kinuya S,Shiba K,Onoguchi M,Kimura H,Hashimoto K,Odani A,Saji H Ann Nucl Med 23 10 843-8
  •  Standardization of the heart-to-mediastinum ratio of 123I-labelled-metaiodobenzylguanidine uptake using the dual energy window method: feasibility of correction with different camera-collimator combinations. Matsuo S,Nakajima K,Okuda K,Kawano M,Ishikawa T,Hosoya T,Taki J,Kinuya S Eur J Nucl Med Mol Imaging 36 4 560-6
  •  Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegenerative diseases. Shiba K,Torashima T,Hirai H,Ogawa K,Akhter N,Nakajima K,Kinuya S,Mori H J Cereb Blood Flow Metab 29 2 434-40
  •  The importance of population-specific normal database for quantification of myocardial ischemia: comparison between Japanese 360 and 180-degree databases and a US database. Nakajima K,Okuda K,Kawano M,Matsuo S,Slomka P,Germano G,Kinuya S J Nucl Cardiol 16 3 422-30
  •  Gated myocardial perfusion SPECT for preoperative risk stratification in patients with noncardiac vascular disease. Kayano D,Nakajima K,Ohtake H,Kinuya S Ann Nucl Med 23 2 173-81
  •  Nuclear medicine practice in Japan: a report of the sixth nationwide survey in 2007. Kuwabara Y,Koizumi K,Ushijima Y,Kinuya S,Kinomura S,Suga K,Takeoka H,Takeda T,Toyama H,Arao Y,Nishiyama Y,Murakami K,Morita K Ann Nucl Med 23 2 209-15
  •  Attenuation correction of myocardial SPECT by scatter-photopeak window method in normal subjects. Okuda K,Nakajima K,Motomura N,Kubota M,Yamaki N,Maeda H,Matsuo S,Kinuya S Ann Nucl Med 23 5 501-6
  •  Clinical usefulness of novel cardiac MDCT/SPECT fusion image. Matsuo S,Nakajima K,Akhter N,Wakabayashi H,Taki J,Okuda K,Kinuya S Ann Nucl Med 23 6 579-86
  •  Evaluation of radioiodinated vesamicol analogs for sigma receptor imaging in tumor and radionuclide receptor therapy. Ogawa K,Shiba K,Akhter N,Yoshimoto M,Washiyama K,Kinuya S,Kawai K,Mori H Cancer Sci 100 11 2188-92
  •  Esophageal transit scintigraphy and structured questionnaire in patients with systemic sclerosis with endoscopically proven reflux esophagitis. Nakajima K,Inaki A,Hiramatsu T,Hasegawa M,Fujimoto M,Takehara K,Kinuya S Ann Nucl Med 23 9 771-6
  •  [The role of / 18FDG PET/CT for the initial staging and therapy in primary breast cancer]. Inokuchi M,Furukawa H,Kayahara M,Ohta T,Kawashima H,Taki J,Kinuya S Gan To Kagaku Ryoho 36 13 2526-31
  •  Biodistribution of humanized anti-VEGF monoclonal antibody/bevacizumab on peritoneal metastatic models with subcutaneous xenograft of gastric cancer in mice. Yagi Y,Fushida S,Harada S,Tsukada T,Kinoshita J,Oyama K,Fujita H,Ninomiya I,Fujimura T,Kayahara M,Kinuya S,Yashiro M,Hirakawa K,Ohta T Cancer Chemother Pharmacol 66 4 745-53
  •  Evaluation of the Olfactory Nerve Transport Function by SPECT-MRI Fusion Image with Nasal Thallium-201 Administration. Shiga H,Taki J,Yamada M,Washiyama K,Amano R,Matsuura Y,Matsui O,Tatsutomi S,Yagi S,Tsuchida A,Yoshizaki T,Furukawa M,Kinuya S,Miwa T Mol Imaging Biol
  •  Biodistribution of humanized anti-VEGF monoclonal antibody/bevacizumab on peritoneal metastatic models with subcutaneous xenograft of gastric cancer in mice. Yagi Y,Fushida S,Harada S,Tsukada T,Kinoshita J,Oyama K,Fujita H,Ninomiya I,Fujimura T,Kayahara M,Kinuya S,Yashiro M,Hirakawa K,Ohta T Cancer Chemother Pharmacol 66 4 745-53
  •  Double-phase (131)I whole body scan and (131)I SPECT-CT images in patients with differentiated thyroid cancer: their effectiveness for accurate identification. Wakabayashi H,Nakajima K,Fukuoka M,Inaki A,Nakamura A,Kayano D,Kinuya S Ann Nucl Med
  •  Quantification of myocardial perfusion SPECT using freeware package (cardioBull). Okuda K,Nakajima K,Hosoya T,Ishikawa T,Matsuo S,Kawano M,Taki J,Kinuya S Ann Nucl Med
  •  Esophageal transit study using a sliding sum image: application to patients with probable and definite systemic sclerosis. Nakajima K,Hasegawa M,Inaki A,Wakabayashi H,Hosoya T,Takehara K,Kinuya S Ann Nucl Med 25 5 325-31
  •  Clinical use of nuclear cardiology in the assessment of heart failure. Matsuo S,Nakajima K,Kinuya S World J Cardiol 2 10 344-56
  •  Early prediction of histopathological tumor response to preoperative chemotherapy by Tc-99m MIBI imaging in bone and soft tissue sarcomas. Taki J,Inaki A,Wakabayashi H,Sumiya H,Tsuchiya H,Zen Y,Kinuya S Clin Nucl Med 35 3 154-9
  •  Comparison of diagnostic value of I-123 MIBG and high-dose I-131 MIBG scintigraphy including incremental value of SPECT/CT over planar image in patients with malignant pheochromocytoma/paraganglioma and neuroblastoma. Fukuoka M,Taki J,Mochizuki T,Kinuya S Clin Nucl Med 36 1 1-7
  •  Semi-automated algorithm for calculating heart-to-mediastinum ratio in cardiac Iodine-123 MIBG imaging. Okuda K,Nakajima K,Hosoya T,Ishikawa T,Konishi T,Matsubara K,Matsuo S,Kinuya S J Nucl Cardiol 18 1 82-9
  •  Identification of myocardial damage in systemic sclerosis: a nuclear cardiology approach. Nakajima K,Matsuo S,Hasegawa M,Kinuya S,Takehara K Int J Rheumatol 2010
  •  123I-metaiodobenzylguanidine imaging in the era of implantable cardioverter defibrillators: beyond ejection fraction. Matsunari I,Taki J,Nakajima K,Kinuya S J Nucl Med 51 8 1171-3
  •  Dynamic expression of tenascin-C after myocardial ischemia and reperfusion: assessment by 125I-anti-tenascin-C antibody imaging. Taki J,Inaki A,Wakabayashi H,Imanaka-Yoshida K,Ogawa K,Hiroe M,Shiba K,Yoshida T,Kinuya S J Nucl Med 51 7 1116-22
  •  Iodine-123 metaiodobenzylguanidine imaging and carbon-11 hydroxyephedrine positron emission tomography compared in patients with left ventricular dysfunction. Matsunari I,Aoki H,Nomura Y,Takeda N,Chen WP,Taki J,Nakajima K,Nekolla SG,Kinuya S,Kajinami K Circ Cardiovasc Imaging 3 5 595-603
  •  I-131 uptake in a thymic cyst. Kayano D,Michigishi T,Ichiyanagi K,Inaki A,Kinuya S Clin Nucl Med 35 6 438-9
  •  Cause of apical thinning on attenuation-corrected myocardial perfusion SPECT. Okuda K,Nakajima K,Matsuo S,Wakabayashi H,Taki J,Kinuya S Nucl Med Commun
  •  Low-dose 123I-metaiodobenzylguanidine diagnostic scan is inferior to 131I-metaiodobenzylguanidine posttreatment scan in detection of malignant pheochromocytoma and paraganglioma. Kayano D,Taki J,Fukuoka M,Wakabayashi H,Inaki A,Nakamura A,Kinuya S Nucl Med Commun 32 10 941-6
  •  The relationship between stress-induced myocardial ischemia and coronary artery atherosclerosis measured by hybrid SPECT/CT camera. Matsuo S,Nakajima K,Okuda K,Kinuya S Ann Nucl Med

Conference Presentations

  • Bringing lutetium-PSMA earlier in prostate cancer(2024/02/01)
  • 核医学治療をご存じですか?(conference:第23回日本内分泌学会九州支部学術大会)(2023/09/02)
  • Development of new bone-seeking radiolabeled compounds(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Building a Normative Database for [18F]-FDG imaging: Insights from a Japanese Screening Cohort(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Comparison of Standardized Uptake Values of [18F]FDG- PET/CT imaging of healthy volunteers: a multi-country PET/CT study(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)

show all

  • Myocardial perfusion imaging with retrospective gating and integrated correction of attenuation, scatter, respiration, motion, and arrhythmia(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Positive Protective Effects of Sigma-1 Receptor Stimulation with Fluvoxamine after Myocardial Ischemia and Reperfusion in Rat(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Dynamic Expression of Myocardial Sigma-1 Receptor in Doxorubicin-Induced Cardiomyopathy using Radioiodine Labeled 2-[4-(2iodophenyl)piperidino]cyclopentanol (OI5V) Imaging(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Automated absolute quantitation of cardiac sympathetic activity using convolutional neural network and 123I-MIBG SPECT/CT(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Flare phenomenon of 99mTc-bone scintigraphy is a determinant of prognosis in patients with metastatic castration-resistant prostate cancer(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Variational autoencoder for detecting coronary artery disease in myocardial perfusion SPECT(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Image characteristics of 99mTc myocardial perfusion SPECT/CT using a new multi-focal collimator: comparison with conventional SPECT with LEHR collimator(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • A machine-learning-based prediction model of lethal arrhythmic events by using the123I-meta- iodobenzylguanidine derived late heart-to-mediastinum ratio: Application into separate Japanese and European cohorts(conference:Congress of European Association of Nuclear Medicine 2023)(2023/09/09)
  • Current situation of RIA examination in Japan(conference:RIA summit in Asia)(2022/05/12)
  • Recent progress of theranostics in Japan (conference:Development of Nuclear Medicine Healthcare and Health Industry Summit in China)(2022/08/05)
  • Recent progress of theranostics in Japan(conference:International Symposium on Honor of the Retirement of Professor Jae Min Jeong)(2021/08/12)
  • Theranostics and future perspective in NET (2021/01/23)
  • 転移DTCに対するRAI治療ー予後不良因子に基づくRAI抵抗性判断の再考(2020/09/29)
  • 転移DTCに対するRAI治療ー予後不良因子に基づくRAI抵抗性判断の再考(2020/07/30)
  • 転移DTCに対するRAI治療ー予後不良因子に基づくRAI抵抗性判断の再考(2020/06/26)
  • Single photon製剤に将来はあるのか?(2020/09/10)
  • 予後不良因子に基づくRAI抵抗性判断の再考(2020/11/26)
  • I-131内用療法の現状と将来展望 (2020/07/17)
  • 放射能でがんを治す - 核医学治療をご存じですか?(2020/02/08)
  • Future direction of precision nuclear medicine(conference:2019 Annual Congress of Korean Society of Nuclear Medicine)(2019/10/25)
  • Theranosticsの現状と展望(2019/09/07)
  • Theranostics in Japan(conference:International Conference on Radiopharmaceutical Therapy 2019)(2019/08/22)
  • Precision Nuclear Medicine(2019/08/30)
  • α線内用療法の有効性(臨床応用に関する基礎的事項)(conference:塩化ラジウム(Ra223)注射液を用いたRI内用療法における適正使用に関する安全取扱講習会)(2019/07/20)
  • Theranostics in Japan (conference:Asia Oceania Congress of Nuclear Medicine and Biology)(2019/05/11)
  • Nuclear theranostics in the world and what is required for the Japanese community (2019/04/12)
  • Theranostics in Japan(conference:5th Theranostics World Congress)(2019/03/01)
  • Precision Nuclear Medicine(2019/01/12)
  • The latest achievement in nuclear medicine(conference:Modern treatment options for thyroid cancer)(2018/09/24)
  • Radioiodine (RAI) therapy in thyroid cancer - its role and timing to switch to TKI (conference:1st Congress of Russian Society for Radiation Oncology)(2018/09/25)
  • 放射免疫療法(radioimmunotherapy)の意義と将来 (conference:RIT Conference 2018)(2018/07/01)
  • Benefit/Risk estimation and radiological protection in special groups (conference:12th Congress of the World Federation of Nuclear Medicine and Biology)(2018/04/23)
  • Treatment of hyperthyroidism Japanese experience (conference:12th Congress of the World Federation of Nuclear Medicine and Biology)(2018/04/23)
  • Scientific writing: Authorship and ethics (conference:12th Congress of the World Federation of Nuclear Medicine and Biology)(2018/04/23)
  • Increasing demand of targeted radionuclide therapy(conference:RI Science Evolution 2018 (RISE18))(2018/03/16)
  • α線内用療法の有効性(臨床応用に関する基礎的事項)(conference:塩化ラジウム(Ra223)注射液を用いたRI内用療法における適正使用に関する安全取扱講習会)(2018/01/13)
  • Future application of theranostics(conference:IAEA/RCA regional training course on theragnostics and dementias)(2017/12/08)
  • Technetium-99m radiopharmaceuticals for other cancer diagnosis (Including related area) (conference:IAEA Technical Cooperation Expert Mission)(2017/11/22)
  • Radiopharmaceuticals for cancer therapy (conference:IAEA Technical Cooperation Expert Mission)(2017/11/22)
  • Utilization of radionuclides in nuclear medicine. Nuclear medicine practice in Japan: a report of the 7th nationwide survey in 2012 + tentative on-going data of the 8th survey in 2017 (conference:Seminar Nasional Pendyagunaan Teknologi Nuklir (SENPATEN))(2017/11/21)
  • Technetium-99m radiopharmaceuticals for bone scan (conference:IAEA Technical Cooperation Expert Mission)(2017/11/22)
  • 放射性医薬品による診断と治療の融合 Radionuclide Theranostics(2017/09/09)
  • 放射性ヨウ素治療の現状から、今後の甲状腺癌治療を考える(2017/10/13)
  • 症例からの治療アプローチ(2017/10/12)
  • How to write scientific papers - authorship and ethics(conference:12th Asia Oceania Congress of Nuclear Medicine and Biology)(2017/10/07)
  • International Symposium Strategies for the future of nuclear medicine(conference:12th Asia Oceania Congress of Nuclear Medicine and Biology)(2017/10/07)
  • Targeted radionuclide therapyの意義 Zevalinを例に(2017/09/25)
  • 放射性ヨウ素治療の現状から今後の甲状腺癌治療を考える (conference:甲状腺セミナーin兵庫)(2017/09/23)
  • 臨床応用(conference: I-131(1,110MBq)による残存甲状腺破壊(アブレーション)の外来治療における適正使用に関する講習会)(2017/09/02)
  • 放射性ヨウ素治療の今後の方向性 (2017/09/02)
  • 腫瘍核医学における最新トピックス (2017/08/31)
  • 放射性ヨウ素治療の現状から今後の甲状腺癌治療を考える (conference:京都放射性ヨウ素治療研究会)(2017/07/21)
  • α線内用療法の有効性(臨床応用に関する基礎的事項)(conference:塩化ラジウム(Ra223)注射液を用いたRI内用療法における適正使用に関する安全取扱講習会)(2017/07/22)
  • RAI(radioactive iodine)不応性を克服できないか?(2017/07/15)
  • Effects of Fukushima Daiichi Nuclear Disaster (conference:Korean Medical Association)(2017/07/01)
  • Radioiodine therapy for thyroid cancer - things we have to think about for the future (conference:Daegyeong Chapter of the Korean Society of Nuclear Medicine)(2017/06/30)
  • Radioiodine therapy and imaging guided strategy(conference:24th Asia Pacific Cancer Conference)(2017/06/23)
  • Radionuclide theranostics(2017/06/20)
  • 放射性ヨウ素治療の現状から今後の甲状腺癌治療を考える(2017/06/17)
  • Radionuclide theranostics(2017/06/20)
  • 内用療法一緒にやってみる?(2017/05/27)
  • Concept of targeted radionuclide therapy For the future of interdisciplinary collaboration (conference:Translational Immunology - from target to therapy IV)(2017/05/05)
  • Targeted radionuclide therapy with 131I-MIBG for malignant neuroendcrine tumors: experience for 14 years(conference:World Association of Radiopharmaceutical and Molecular Therapy)(2015/10/31)
  • 基礎と安全管理 放射性同位元素の取扱(2017/04/22)
  • RI内用療法(本邦における最近のトピック)(2017/04/23)
  • 分子標的薬の開始基準を考える From 核医学的 point of view (2017/03/31)
  • Recent advance in targeted radionuclide therapy: toward individualized evidence based medicine(conference:15th International Congress of Radiation Reseach)(2015/05/26)
  • Present status and strategy to develop targeted radionuclide therapy in Japan(conference:Asia Regional Cooperative Council of Nuclear Medicine)(2016/07/15)
  • Recent basic researches on targeted radionuclide therapy in Japan(conference:11th International Conference on Radiopharmaceuticlas)(2016/11/14)
  • Establishment of National Congress of Targeted Radionuclide Therapy(conference:17th Chinese Symposium on Nuclear Cardiology)(2016/07/01)
  • Tharanostic use of "オクトレオスキャン”(conference:NET Progress Japan)(2017/02/25)
  • Way to develop targeted radionuclide therapy in Japan(conference:The 3rd International Symposium on Targeted Radionuclide Therapy)(2017/02/12)
  • Radionuclide theranostics(2017/06/20)

Others

  •  Optimization of radioimmunotherapy interactions with hyperthermia 20 2 190-200 2004/03
  •  99mTc-sestamibi to monitor treatment with antisense oligodeoxynucleotide complementary to MRP mRNA in human breast cancer cells. 2006
  •  Binding with serum components favorably affects cellular uptake of 111In-oligonucleotide in a leukemia cell line. 2006
  •  Changes of 99mTc-sestamibi uptake in P-glycoprotein expressing leukemia cells treated in vivo with antisense oligodeoxynucleotide complementary to mdr-1 mRNA. 2006
  •  Respiratory distress caused by radioiodine therapy in aptients with differentiated thyroid cancer. 2006

show all

  •  Eradication of colon cancer cells before tumour formation in the peritoneal cavity of mice treated with intraperitoneal Re-186 radioimmunotherapy. 2006
  •  Radioiodinated VEGF to image tumor angiogenesis in a LS180 tumor xenograft model. 2006
  •  simple and rapid radiochemical choline acetyltransferase (ChAT) assay screening test. 2006
  •  herapeutic effects for the palliation of metastatic bone pain of a rhenium-186 complex-conjugated bisphosphonate in an animal model. 2007
  •  Changes in the levels of CD4+ and CD8+ T-lymphocytes after strontium-89 chloride therapy for painful bone metastases in patients correlate with treatment efficacy. 2007
  •  Correction of iodine-123-labeled meta-iodobenzylguanidine uptake with multi-window methods for standardization of the heart-to-mediastinum ratio. 2007
  •  Effect of postconditioning on myocardial 99mTc-Annexin-V uptake: comparison with Ischemic preconditioning and caspase Inhibitor treatment. 2007

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「高リスク化学療法不応性神経芽腫に対する新治療戦略の開発」(2021-2021) 
○「高リスク化学療法不応性神経芽腫に対する新治療戦略の開発」(2020-2021) 
○「高リスク化学療法不応性神経芽腫に対する新治療戦略の開発」(2019-2021) 
○「進行消化器癌に対するα線核種内照射療法による治療戦略の確立」(2018-2018) 
○「進行消化器癌に対するα線核種内照射療法による治療戦略の確立」(2016-2018) 
○「悪性神経内分泌腫瘍に対する131I-MIBG内照射療法の開発」(2015-2017) 
○「悪性神経内分泌腫瘍に対する分子生物学的・組織学的特徴に基づいた集学的内照射療法」(2010-2011) 
○「悪性神経内分泌腫瘍に対する血管新生阻害下内用療法:基礎研究から臨床応用へ」(2007-2009) 
○「癌細胞膜アビジン発現とスカベンジャー受容体内在化による特異的普遍的内照射療法の開発」(2004-2006) 
○「放射性化合物内照射療法と血管新生阻害療法との同調効果による癌転移巣の制御」(2002-2003) 
○「DNA修復阻害・腫瘍内酸素化改善による放射性医薬品内照射療法の抗腫瘍効果増強」(2000-2001) 
○「腫瘍血行動態改善による放射能標識モノクローナル抗体の治療効果増強に関する研究」(1997-1998) 
○「原発性アルドステロン症における新治療戦略ー安全かつ高奏功な根本治療の開発」(2022-2025) 
○「細胞内レドックス制御を司るがん幹細胞治療の標的トランスポーター画像診断薬の開発」(2022-2025) 
○「放射線療法の提供体制構築に資する研究」(2021-2022) 
○「高リスク化学療法不応性神経芽腫に対する新治療戦略の開発」(2019-2021) 
○「高リスク化学療法不応性神経芽腫に対する新治療戦略の開発」(2019-2021) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Nuclean Medicine(BSL)(2017)
○Nuclean Medicine(BSL)(2016)

Classes (Graduate Schools)

○Introduction to Medical Science(2021)
○Exploring and preventive diagnostics(2021)
○Biotracer Medicine(2021)
○Biotracer Medicine(2021)
○Exploring and preventive diagnostics(2017)
○Biotracer Medicine(2017)
○Biotracer Medicine(2017)
○Biotracer Medicine(2017)
○Biotracer Medicine(2016)
○Biotracer Medicine(2016)
○Exploring and preventive diagnostics(2016)
○Biotracer Medicine(2016)

International Project

○IAEA workshopIAEA, 日本外務省(20191205-20191208)program organizer
○IAEA Scientific visitIAEA(20191125-20191128)program organizer
○Workshop on Paediatric Nuclear Medicine (including Paediatric Oncology)(20190221-20210331)Organizer on Workshop on Paediatric Nuclear Medicine (including Paediatric Oncology)
○Supporting IAEA technical cooperative programmes for human resources development in radiation medicine(2018-2021)

International Students

Lecture themes

Others (Social Activities)

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