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Researcher Information

last modified:2020/01/22

Associate Professor TORIBA Akira

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Faculty, Affiliation

Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences
Associate Professor

College and School Educational Field


Division of Environmental Design, Graduate School of Natural Science and Technology
School of Pharmacy, College of Medical, Pharmaceutical and Health Sciences
School of Pharmaceutical Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Hygienic Chemistry TEL:076-234-4457 FAX:076-234-4456

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kitasato University Master 199703 Completed
The University of Tokyo Doctor 199905 Unfinished course
【Academic background(Bachelor's Degree)】
Kitasato University Faculty of Pharmaceutical Sciences 199503

Career

Kanazawa University(1999/06/01-2005/03/31)
Kanazawa University(2005/04/01-)

Year & Month of Birth

1973/01

Academic Society

Japan Society for Environmental Chemistry



Japan Society for Atmospheric Environment

Award


Specialities

、、Environmental and hygienic pharmacy、Environmental impact assessment、Analytical chemistry、Atmospheric Environmental Chemistry

Speciality Keywords

Air pollution, Indoor pollution, Particulate matter, Combustion sources, Polycyclic aromatic hydrocarbons, Sensitive analysis, Carcinogenic compounds, Reactive oxygen species, Oxidative stress, biomarkmer

Research Themes

Development of sensitive analytical methods for organic pollutants using mass spectrometry and its application to environmental samples

Sensitive and selective analytical methods using mass spectrometry are developed for determining environmental organic pollutants with sensitive techniques such as derivatization. The developed methods are applied to actual environmental samples.

Study on the generation of reactive oxygen species by atmospheric particulate matters

The adverse health effects induced by particulate matter (PM) are associated with oxidative stress derived from reactive oxygen species (ROS) generation. Polycyclic aromatic hydrocarbon quinones (PAHQs), existed in PM, cause a chain reaction; redox cycle, in which PAHQs catalytically undergoes reduction and oxidation with the generation of ROS. In this study, we are observing ROS activities for 40 PAHQs and ambient PM samples and the contribution of PAHQs to the ROS generation of the PM samples.

Study on Human Exposure to Organic Pollutants through Environmental PM2.5 and Nanoparticles

We are developing a portable nanoparticle sampler using inertial filter technology which can separate PM2.5 into 4 particle size fractions and evaluated the usefulness of the sampler in the actual environment. Using the developed sampler, atmospheric concentrations, compositions of organic pollutants and the contribution to PM2.5 regarding PM0.1 are evaluated in several life environments (microenvironments).

Analysis of polycyclic aromatic hydrocarbon metabolites excreted in the bile of Japanese Red crowned crane (Grus japonensis)

Japanese Red-crowned crane (Grus japonensis) inhabits the marsh in the eastern Hokkaido. Nowadays, it lives near human beings because of the decrease of the marsh and the increase of its population. So, it is concerned that Red-crowned cranes are exposed to more anthropogenic chemicals. Polycyclic aromatic hydrocarbons (PAHs) are released into the environment as a result of incomplete combustion of organic matter such as fossil fuels. PAHs can cause hemolytic anemia, immunosuppression to birds. Therefore, it is important to investigate the exposure levels of PAHs for their protection. In this study, we are developing analytical methods for hydroxylated polycyclic aromatic hydrocarbons (OHPAHs), the metabolite of PAH, excreted in the bile of Red-crowned crane using liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Study for the evaluation of the exposure to polycyclic aromatic hydrocarbons

Books

  •  Determination of 1-nitropyrene metabolites by high performance liquid chromatography with chemiluminescence detection. 1107 286-289 2006/01
  •  Simultaneous determination of urinary hydrxylated metabolites of naphthalene, fluorine, phenanthrene, fluoranthene and pyrene as multiple biomarkers of exposure to polycyclic aromatic hydrocarbons. 386 712-718 2006/08
  •  Direct measurement of the glucuronide conjugate of 1-hydroxypyrene in human urine by using liquid chromatography with tandem mass spectrometry 867  259-263 2008/05
  •  Hayakawa, K.(Ed.), Nagato, E.G., Tang, N., Toriba, A., Yang, X., Simpson, C.D., Kameda, T., Pham, C.T., Chetiyanukornkul T., Nassar, H.F., Inomata, Y., Chizhova, T., Bekki, K., Nakajima, D., Suzuki, N. Polycyclic Aromatic Hydrocarbons -Environmental Behavior and Toxicity in East Asia Springer Nature 2018/02

Papers

  •  A High-Performance Liquid Chromatographic System Equipped with Reducer and Concentrator Columns for Determination of Trace Levels of Nitropolycyclic Aromatic Hydrocarbons in Extracts from Diesel-Engine Exhaust Particulates. Anal. Chim. Acta 445 205-212 2001
  •  A High-Performance Liquid Chromatographic System Equipped with Reducer and Concentrator Columns for the Determination of Trace Level of Nitropolycyclic Aromatic Hydrocarbons in Extracts from Diesel-Engine Exhaust Particulates. LUMINESCENCE 15 2 85-86 2000
  •  Amino acid sequence and D/L-configuration determination methods for D-amino acid-containing peptides in living organisms. Biomed. Chromatogr. 15 319-327 2001
  •  BF3?methanol as a cyclization/cleavage/conversion reagent for suppression of amino acid racemization in Edman sequencing and l-configuration determination method. Anal. Chim. Acta 429 293?300 2001
  •  Comparison of Atmospheric Nitropolycyclic Aromatic Hydrocarbons in Vladivostok, Kanazawa and Toyama. JOURNAL OF HEALTH SCIENCE 48 1 30-36 2002/01

show all

  •  Quantification of 2-Hydroxyfluorene in Human Urine by Column-switching High Performance Liquid Chromatography with Fluorescence Detection ANALYST 128 605-610 2003/02
  •  Comparison of Polycyclic Aromatic Hydrocarbons and Nitropolycyclic Aromatic Hydrocarbons in Airborne and Automobile Exhaust Particulates. POLYCYCLIC AROMATIC COMPOUNDS 20 179-190 2000
  •  Considerations of Atmospheric Behaviors of Polycyclic Aromatic Hydrocarbons, Nitropolycyclic Aromatic Hydrocarbons and Inorganic Pollutants Based on Their Interrelationships. J. Health Sci. 47 4 385-393 2001
  •  Detection of DBD-Carbamoyl Amino Acids in Amino Acid Sequence and D/L Configuration Determination of Peptides with Fluorogenic Edman Reagent, 7-[(N,N-Dimethylamino)sulfonyl]-2,1,3-benzoxadiazolyl-4-yl Isothiocyanate. Anal. Biochem. 270 257-267 1999
  •  Development of an Amino Acid Sequence and D/L-Configuration Determination Method of Peptide with a New Fluorescence Edman Reagent, 7-Methylthio-4-(2,1,3-benzoxadiazolyl) Isothiocyanate. Anal. Chem. 72 732-739 2000
  •  Dtection of 7-N,N-Dimethylaminosulfonyl-4-(2,1,3-benzoxadiazolyl) Carbamoyl Amino Acids Generated by Post-column Desulfuration in the Simultaneous Determination of the Sequence and D/L-Configuration of Peptides using a Fluorogenic Edman Reagent, 7-N,N-Dim Anal. Chim. Acta 415 57-66 2000
  •  Estrogenic/Antiestrogenic Activities of Benzo[a]pyrene Monohydroxy Derivatives. J. Health Sci. 47 6 552-558 2001
  •  Micellar electrokinetic chromatography of monohydroxybenzo[a]pyrene positional isomers using γ-cyclodextrin. ANALYST 125 8 1555-1559 2000
  •  原油湧出土から単離した菌株によるナフタレンの代謝分解. 水環境学会誌 23 11 731-736 2000
  •  Comparison of Atmospheric Polycyclic Aromatic Hydrocarbons in Vladivostok, Toyama and Kanazawa Bulletin of the Japan Sea Research Institute of Kanazwa Univ. 33 77-86 2002/01
  •  Determination of 1-Hydroxypyrene in Human Urine by HPLC with Fluorescence Detection Using a Deuterated Internal Standard JOURNAL OF CHROMATOGRAPHY A 961 1 107-112 2002/01
  •  Comparison of Atmospheric Polycyclic Aromatic Hydrocarbons and Nitropolycyclic aromatic Hydrocarbons in an Industrialized City (Kitakyushu) and Two Commercial.. JOURNAL OF HEALTH SCIENCE 48 4 370-375 2002/01
  •  Antiestrogenic Activity of Extracts of Diesel Exhaust Particulate Matter in MCF-7 Human Breast Carcinoma Cells POLYCYCLIC AROMATIC COMPOUNDS 22 3-4 747-759 2002/01
  •  Determination of benzo[a]pyrene metabolites by human cytochrome P450 using column-switching HPLC with fluorescence detection LUMINESCENCE 17 4 213-214 2002/01
  •  Analysis of urinary 2-hydroxyfluorene as a new biological marker of the exposure to polycyclic aromatic hydrocarbons LUMINESCENCE 17 4 282-284 2002/01
  •  Simultaneous determination of monohydroxybenzo[a]pyrene positional isomers by reversed-phase liquid chromatography coupled to electr... BIOMEDICAL CHROMATOGRAPHY 16 7 432-436 2002/01
  •  Comparison of Polycyclic Aromatic Hydrocarbons and Nitropolycyclic Aromatic Hydrocarbons in Airborne Particulates Collected in Downtown and Suburba... ATMOSPHERIC ENVIRONMENT 36 35 5535-5541 2002/01
  •  Method of determining monohydroxybenzo[a]pyrene isomers using column-switching high-performance liquid chromatography ANALYTICAL BIOCHEMISTRY 312 1 14-22 2003/01
  •  Improvement of an Automatic HPLC System for Nitropolycyclic Aromatic Hydrocarbons: Removal of an Interfering Peak and Increase in the Number of Analytes ANALYTICAL SCIENCES 19 2 249-253 2003/02
  •  Quantification of Polycyclic Aromatic Hydrcarbons (PAHs) in Human Hair by HPLC with Fluorescence Detection: A Biological Monitoring Method to Evaluate t.... BIOMEDICAL CHROMATOGRAPHY 17 2-3 126-132 2003/01
  •  Urinary 2-hydroxyfluorene and 1-hydroxypyrene levels in smokers and non-smokers in Japan and Thailand. POLYCYCLIC AROMATIC COMPOUNDS 24 4-5 467-474 2004/01
  •  Evaluation of Estrogenic Activities of Hydroxylated Polycyclic Aromatic Hydrocarbons in Cigarette Smoke Condensate. FOOD AND CHEMICAL TOXICOLOGY 43 1017-1027 2005/05
  •  Direct-Acting Mutagenicity of Extracts of Coal Burning-Derived Particulates and Contribution of Nitropolycyclic Aromatic Hydrocarbons. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 581 91-95 2005/01
  •  Simultaneous determination of twenty-one mutagenic nitropolycyclic aromatic hydrocarbons by high-performance liquid chromatography with chemiluminescence detection. Proceedings of the 13th International Symposium Bioluminescence & Chemiluminesce 441-444 2005/05
  •  Hair Analysis of Nicotine and Cotinine for Evaluating Tabacco Smoke Exposure by Liquid Chromatography-mass Spectrometry. BIOMEDICAL CHROMATOGRAPHY 18 9 655-661 2004/09
  •  Variation in the Antiandrogenic Activity of Diesel Exhaust Particulates Emitted under Different Engine Loads. POLYCYCLIC AROMATIC COMPOUNDS 24 4-5 743-757 2004/05
  •  Transfer of Polycyclic Aromatic Hydrocarbons to Fetuses and Breast Milk of Rats Exposed to Diesel Exhaust. JOURNAL OF HEALTH SCIENCE 50 5 497-502 2004/05
  •  Comparison of Compositions of Polychlorinated Dibenzo-p-dioxins (PCDDs) and Dibenzofurans (PCDFs) in Air and Soil Samples Collected in Ishikawa. JOURNAL OF HEALTH SCIENCE 50 1 58-65 2004/01
  •  Antiandrogenic Activity of Extracts of Diesel Exhaust Particles Emitted from Diesel-Engine Truck under Different Engine Loads and Speeds. TOXICOLOGY 195/2 3 243-254 2004/03
  •  Determination of Atmospheric Nitrobenzanthrones by High-Performance Liquid Chromatography with Chemiluminescence Detection. ANALYTICAL SCIENCES 20 1 119-123 2004/01
  •  A new Luciferase Reporter Gene Assay for Detection of Androgenic and Antiandrogenic Effects Based on a Human Prostate Specific Antigen Promoter and PC3/AR Human Prostate Cancer Cells. ANALYTICAL SCIENCES 20 1 55-59 2004/01
  •  Antiandrogenic Activities of Diesel Exhaust Particule Extracts in PC3/AR Human Prostate Carcinoma Cells. TOXICOLOGICAL SCIENCES 76 299-309 2003/12
  •  Photodegradation of 4-alkyphenols using BiVO4 photocatalyst under irradiation with visible light from a solar simulator. APPLIED CATALYSIS B-ENVIRONMENTAL 46 3 573-586 2003/10
  •  A Role of Aryl Hydrocarbon Receptor in the Antiandrogenic Effects of Polycyclic Aromatic Hydrocarbons in LNCaP Human Prostate Carcinoma Cells. ARCHIVES OF TOXICOLOGY 77 335-343 2003/01
  •  Activation of 5-lipoxygenase and NF-κB in the action of acenaphthenequinone by modulation of oxidative stress Chung, S.-W., Toriba, A., Chung, H.-Y., Yu, B.-P., Kameda, T., Tang, N., Kizu, R., Hayakawa, K. TOXICOLOGICAL SCIENCES 101 1 152-158 2007/12
  •  Identification of Estrogenic/Anti-Estrogenic Compounds in Diesel Exhaust Particulate Extract Noguchi, K., Toriba, A., Chung, S.-W., Kizu, R., Hayakawa, K. BIOMEDICAL CHROMATOGRAPHY 21 11 1135-1142 2007/12
  •  Estrogenic/Antiestrogenic Activities of Polycyclic Aromatic Hydrocarbons and Their Monohydroxylated Derivatives by Yeast Two-Hybrid Assay Hayakawa, K., Onoda, Y., Tachikawa, C., Hosoi, S., Yoshita, M., Chung, S.-W., Kizu, R., Toriba, A., Kameda, T., and Tang, N. JOURNAL OF HEALTH SCIENCE 53 5 562-570 2007/12
  •  Analysis of 1-nitropyrene in air particulate matter standard reference materials by using two-dimensional high performance liquid chromatography with online reduction and tandem mass spectrometry detection Miller-Schulze, J. P., Paulsen, M., Toriba, A., Hayakawa, K., Simpson, C. D. JOURNAL OF CHROMATOGRAPHY A 1167 154-160 2007/12
  •  Identification and Quantification of 1-Nitropyrene Metabolites in Human Urine as a Proposed Biomarker for Exposure to Diesel Exhaust Toriba, A., Kitaoka, H., Dills, R., Mizukami, S., Tanabe, K.,Takeuchi, N., Ueno, M., Kameda, T., Tang, N., Hayakawa, K., Simpson, C. CHEMICAL RESEARCH IN TOXICOLOGY 20 7 999-1007 2007/12
  •  Long-Range Transportation of Polycyclic Aromatic Hydrocarbons from China to Japan Yang, X.-Y., Okada, Y., Tang, N., Matsunaga, S., Tamura, K., Lin, J-M., Kameda, T., Toriba, A., Hayakawa, K. ATMOSPHERIC ENVIRONMENT 41 2710-2718 2007/12
  •  Atmonspheric Environment in the Northeast Region of China in View of Polycyclic Aromatic Hydrocarbons and Nitropolycyclic Aromatic Hydrocarbons Tang, N., Tamura, K., Yang, X.-Y., Kameda, T., Toriba, A., Hayakawa, K. J. Ecotechnology Research 13 1 35-42 2007/12
  •  Study on Atmospheric Polycyclic Aromatic Hydrocarbons at a Background Site of Ishikawa Prefecture, Japan Yang, X.-Y., Okada, Y., Tang, N., Toriba, A., Hayakawa, K. J. Ecotechnology Research 13 1 5-9 2007/04
  •  Profiles of Particulate-Bound Polycyclic Aromatic Hydrocarbons and Their Nitrated Derivatives in Three Typical Cities, Liaoning Province, China Hattori, T., Tang, N., Tamura, K., Hokoda, A., Yang, X.-Y., Igarash K., Ohno, M., Okada, Y., Kameda, T., Toriba, A., Hayakawa, K. ENVIRONMENTAL FORENSICS 8 165-172 2007/12
  •  Rapid and sensitive determination of tryptophan, serotonin and psychoactive tryptamines by thin-layer chromatography/fluorescence detection Kato, N., Kojima, T., Yoshiyagawa, S., Ohta, H., Toriba, A., Nishimura, H., Hayakawa, K. JOURNAL OF CHROMATOGRAPHY A 1145 229-233 2007/12
  •  Nitro-polycyclic aromatic hydrocarbon concentrations in urban air particulate matter and their implications for source apportionment in Shenyang, China. EPIDEMIOLOGY 19 6 S185 2008/05
  •  Evaluation of endocrine disrupting activities of monohydroxylated derivatives of 1-nitropyrene by yeast two-hybrid assay. JOURNAL OF HEALTH SCIENCE 54 1 118-122 2008/02
  •  Thin layer chromatography/fluorescence detection of 3,4-methylenedioxy- methamphetamine and related compounds. JOURNAL OF FORENSIC SCIENCES 53 6 1367-1371 2008/09
  •  Interaction of hydroxylated polycyclic aromatic hydrocarbons to estrogen receptor. POLYCYCLIC AROMATIC COMPOUNDS 28 4 382-391 2008/10
  •  Analysis of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in gas/particle phases separately collected by a high-volume air sampler equipped with a column packed with XAD-4 resin. JOURNAL OF HEALTH SCIENCE 55 1 77-85 2009/01
  •  Monohydroxylated polycyclic aromatic hydrocarbons inhibit both osteoclastic and osteoblastic activities in teleost scales. LIFE SCIENCES 84 13-14 482-488 2009/10
  •  Long-range transport of fluoride in East Asia monitored at Noto Penninsula, Japan.  SCIENCE OF THE TOTAL ENVIRONMENT 407 16 4681-4686 2009/10
  •  Determination of airborne particle-associated benz[a]anthracene-7, 12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection. JOURNAL OF CHROMATOGRAPHY A 1216 39 6758-6761 2009/12
  •  Oxidative stress more strongly induced by ortho- than para- quinoid polycyclic aromatic hydrocarbons in A549 cslls. JOURNAL OF HEALTH SCIENCE 55 5 845-850 2009/08
  •  Determination of nivalenol and deoxynivalenal by liquid chromatography/atmospheric pressure photoionization mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY 23 19 3119-3124 2009/11
  •  Determination of 1-nitropyrene in low volume anbient air samples by high-performance liquid chromatography with fluorescence detection. JOURNAL OF CHROMATOGRAPHY A 1216 21 4625-4628 2009/11
  •  Exposures to particulate air pollution and nitro-polycyclic aromatic hydrocarbons among taxi drivers in Shenyang, China. ENVIRONMENTAL SCIENCE & TECHNOLOGY 44 1 216-221 2010/01
  •  Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 695 1-2 29-34 2010/01
  •  A Survey of the occurrence of fusarium mycotoxins in biscuits in Japan by using LC/MS. JOURNAL OF HEALTH SCIENCE 56 2 188-194 2010/02
  •  Determination of Fusarium mycotoxins by liquid chromatography/tandem mass spectrometry coupled with immunoaffinity extraction. RAPID COMMUNICATIONS IN MASS SPECTROMETRY 24 16 2445-2452 2010/10
  •  Determination of particle-associated hydroxynitropyrenes with correctionfor chemical degradation on a quartz fibre filter during high volume air sampling. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY 90 13 976-987 2010/12
  •  中国・北京及び日本・金沢の大気が示すAhR活性化作用へのPAH類及びダイオキシン類の寄与. J. Environ. Chem. 21 1 27-33 2011/02
  •  Atmospheric formation of hydroxynitropyrenes from a photochemical reaction of particle-associated 1-nitropyrene. ENVIRONMENTAL SCIENCE & TECHNOLOGY 45 8 3325-3332 2011/03
  •  Direct measurement of the glucuronide conjugate of 1-hydroxypyrene in human urine by using liquid chromatography with tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY B 867 259-263 2008/05
  •  Thin layer chromatography/fluorescence detection of 3,4-methylenedioxy- methamphetamine and related compounds Kato, N., Fujita, S., Ohta, H., Fukuba, M., Hayakwa, K. J. Forensic Sci. 53 6  1367-1371 2008/05
  •  Biological Effects of Polycyclic Aromatic Hydrocarbon Derivatives. Bekki, K., Tang, N., Kameda, T., Hayakawa, K., 産業医科大学雑誌 35 1 17-24 2013/01
  •  A-clean-up method by photocatalysis for HPLC analysis of iprodione in dry basil. Maeda, O., Oikawa, C., Shiomi, N., Hayakawa, K. Anal. Sci. 24 8  1053-1055 2008/11
  •  Simple Method for Determination of Fungicides in Citrus Fruits by Liquid Chromatography–Tandem Mass Spectrometry. Kakimoto, Y., Takatori, S., Okihashi, M., Kajimura, K., Toriba, A., Hayakawa, K. Food Anal. Methods in press
  •  Quantification of iprodione in dry basil using silica gel supported titanium dioxide. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 58 3 1416-1419 2010/02
  •  日本および中国における大気粒子中多環芳香族炭化水素キノンの観測-濃度レベルの把握と発生要因の検討- J. Jpn. Soc. Atmos. Environ. 46 1 20-29 2011/01
  •  Mutagenicities and endocrine-disrupting activities of 1-hydroxy-2-nitropyrene and 1-hydroxy-5-nitropyrene. JOURNAL OF HEALTH SCIENCE 57 4 372-377 2011/10
  •  Estrogenic/antiestrogenic activities of quinoid polycyclic aromatic hydrocarbons. JOURNAL OF HEALTH SCIENCE 57 3 274-280 2011/10
  •  Hydrogen peroxide-sodium hydrosulfite chemiluminescence system combined with high-performance liquid chromatography for determination of 1-hydroxypyrene in airborne particulates. TALANTA 85 5 2711-2714 2011/10
  •  Recent change in atmospheric polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (NPAHs) in Shenyang, China. ENVIRONMENTAL FORENSICS 12 342-348 2011/12
  •  Atmospheric concentrations of polycyclic aromatic hydrocarbons and selected nitrated derivatives in Greater Cairo, Egypt. ATMOSPHERIC ENVIRONMENT 45 39 7352-7359 2011/07
  •  金沢市内における大気粉塵中多環芳香族炭化水素類およびニトロ多環芳香族炭化水素類の最近12年間の変遷 J. Jpn. Soc. Atmos. Environ. 47 1 1-8 2012/01
  •  On-line concentration and fluorescence determination HPLC for polycyclic aromatic hydrocarbons in seawater samples and its application to Japan sea. CHEMICAL & PHARMACEUTICAL BULLETIN 60 4 531-535 2012/02
  •  多環芳香族炭化水素類の生体影響に対し輸送及び生体内代謝がどのように関与しているのか. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 893-894 173-176 2012/03
  •  Determination of benzo[a]pyrene-7, 10-quinone in airborne particulates by using a chemiluminescence reaction of hydrogen peroxide and hydrosulfite. ANALYTICAL CHEMISTRY 84 7 3215-3221 2012/05
  •  Analysis of 8-hydroxy-2'-deoxyguanosine in human urine using hydrophilic interaction chromatography with tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY B 893-894 173-176 2012/08
  •  Evaluation of urinary metabolites of 1-nitropyrene as biomarkers for exposure to diesel exhaust in taxi drivers in Shenyang, China JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY 44 1 216-221 2012/01
  •  Personal and atmospheric concentrations of ozone in southeastern Hyogo prefecture, Japan. CHEMICAL & PHARMACEUTICAL BULLETIN 60 8 962-966 2012/08
  •  Decrease in the matrix effect of GC/MS by a gold-plated ion source. JOURNAL OF PESTICIDE SCIENCE 37 2 148-155 2012/03
  •  Search of components causing matrix e_ects on GC/MS for pesticide analysis in food. JOURNAL OF PESTICIDE SCIENCE 37 2 156-163 2012/03
  •  Gene expression changes of phase I and II metabolizing enzymes induced by PAH derivatives. POLYCYCLIC AROMATIC COMPOUNDS 32 2 141-153 2012/04
  •  Atmospheric formation of hydroxynitrofluoranthene from photochemical reactions of 2-nitrofluoranthene. POLYCYCLIC AROMATIC COMPOUNDS 32 2 177-187 2012/04
  •  Characteristics of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in Hanoi-Vietnam, as a typical motorbike city. POLYCYCLIC AROMATIC COMPOUNDS 32 2 296-312 2012/04
  •  Deoxidation of fenthion sulfoxide, fenthion oxon sulfoxide and fensulfothion in gas chromatograph/mass spectrometer, and the prevention of sulfoxide deoxidation by polyethylene Glycol 300 ANALYTICAL SCIENCES 28 7 669-673 2012/08
  •  Detection of dechlorane plus and brominated flame retardants in marketed fish in Japan. CHEMOSPHERE 89 4 416-419 2012/10
  •  An analytical method for measuring α-amylase activity in starch-containing foods. BIOMEDICAL CHROMATOGRAPHY 27 5 583-588 2012/11

Conference Presentations

  • Analysis of polycyclic aromatic hydrocarbon metabolites excreted in the bile of Japanese Red crowned crane(2018/03/26)
  • Simultaneously determination of polycyclic aromatic hydrocarbons and their nitro-derivatives by using two-dimensional HPLC with on-line reduction and fluorescence detection(2017/09/11)
  • Assessment of the contribution of polycyclic aromatic hydrocarbon quinones on the generation of reactive oxygen species by atmospheric particulate matters(2017/09/01)
  • Size distribution of PAHs and ClPAHs in atmospheric particles(2017/06/07)
  • Characterristic of polycyclic aromatic hydrocarbons in PM2.5 in Beijing, China(conference:137th Annual Meeting of the Pharmaceutical Society of Japan )(2017/03/27)

show all

  • Source identification of PM2.5 using polycyclic aromatic hydrocarbons as markers(conference:137th Annual Meeting of the Pharmaceutical Society of Japan )(2017/03/27)
  • Size distribution of atmospheric quinoid polycyclic aromatic hydrocarbons in atmospheric particulate matter(conference:137th Annual Meeting of the Pharmaceutical Society of Japan )(2017/03/27)
  • Effects of air pollution on the health of school children in Beijing, China(conference:137th Annual Meeting of the Pharmaceutical Society of Japan)(2017/03/27)
  • Analysis of polycyclic aromatic hydrocarbons in environmental nanoparticles from ship exhausts collected at sea of Tokyo Bay(2016/09/11)
  • Assessment of the contribution of polycyclic aromatic hydrocarbon quinones to on the generation of reactive oxygen species by atmospheric particulate matters(2016/09/10)
  • 衛生試験法・注解 空気試験法 多環芳香族炭化水素(新規(conference: 137th Annual Meeting of the Pharmaceutical Society of Japan )(2017/03/26)

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「ベンゾ[a]ピレン及びその代謝物の内分泌撹乱作用の評価法に関する研究」(2001-) 
○「多環芳香族炭化水素類(PAH)-DNA付加体を指標とするPAH曝露評価法の開発」(2005-) 
○「変異原性環境化学物質,ニトロ多環芳香族炭化水素類の人体曝露評価法の開発」(2003-) 
○「多環芳香族炭化水素とその代謝物の内分泌撹乱作用とその測定法に関する研究」(2003-) 
○「多環芳香族炭化水素類(PAHs)のホルモン活性等価係数(HAEF)の確立」(2002-) 
○「アジア産マオウ科マオウ属植物の学際的調査研究」(2001-) 
○「経気道曝露する未規制多環芳香族炭化水素の健康リスク評価に関する研究」(2002-) 
○「アジア諸地域住民の大気汚染曝露実態と生体影響の国際比較」(2011-2014) 
○「含硫黄多環芳香族化合物を指標とする越境大気汚染物質の人体曝露評価法の開発」(2012-2014) 
○「酸化ストレスを惹起するキノン系化合物の人体曝露評価法の開発」(2009-2010) 

Classes (Bachelors)

○Hygienic Pharmacy 1(2017)
○Analytical, Environmental and Physical Sciences(2017)
○Experiments in Analysis and Measurements 2(2017)
○Hygienic Pharmacy 2(2017)
○Experiments in Fundamental Chemistry(2016)
○Experiments in Analysis and Measurements 3(2016)
○Laboratory Rotation 1(2016)
○Hygienic Pharmacy 2(2016)
○Hygienic Pharmacy 1(2016)
○Analytical, Environmental and Physical Sciences(2016)

Classes (Graduate Schools)

○Environment and Health -Introductory(2017)
○Introduction to Pharmachemistry(2017)
○Advanced Seminar on Pharmachemistry(2017)
○Bioinorganic Chemistry(2017)
○Advanced Course of Pharmachemistry(2017)
○Advanced Organic Chemistry III(2017)
○Quantum Organic Chemistry(2017)
○Environmental Risk Assessment(2017)
○Environment and health(2016)
○Environmental Hygenic Chemistry(2016)
○Environment and Health -Introductory(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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