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Researcher Information

last modified:2021/03/30

Associate Professor IYORI Mitsuhiro

Laboratory Website

Faculty, Affiliation

Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy

College and School Educational Field

Division of Health Sciences, Graduate School of Phamaceutical Science
Graduate School of Phamateutical Sciences
School of Pharmaceutical Sciences, College of Medical, Pharmaceutical and Health Sciences
School of Pharmacy, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Laboratory of Vaccinology and Applied Immunology TEL:076-234-4464 FAX:076-234-4464

Academic Background

【Academic background(Doctoral/Master's Degree)】
Hokkaido University Doctor 200903 Completed
【Degree】
Ph.D

Career

Kanazawa University School of Pharmacy Associate Professor(2015/10/01-)
Kanazawa University School of Pharmacy Assistant Professor(2011/02/01-2015/09/30)
Dartmouth Medical School Microbiology & Immunology Research associate(2009/08/01-2011/01/31)
Hokkaido University Graduate School of Dental Medicine Research associate(2009/04/01-2009/07/31)

Year & Month of Birth

1977/11

Academic Society





Award

Specialities

Biological pharmacy

Speciality Keywords

Research Themes

The development of malaria vaccines based on viral vectors

The development of anti-platelet agents based on the salivary protein of mosquitoes

Books

Papers

  •  A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies.  Mitsuhiro Iyori, Ryohei Ogawa, Talha Bin Emran, Shuta Tanbo, Shigeto Yoshida Gene Expression 2021/10/28
  •  A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies.  Yusuf Y, Yoshii T, Iyori M, Mizukami H, Fukumoto S, Yamamoto DS, Emran TB, Amelia F, Islam A, Syafira I, Yoshida S.  Frontiers in Immunology 10 2412 2019/10/15 
  •  Down‐selecting circumsporozoite protein‐based malaria vaccine: a comparison of malaria sporozoite challenge model Amelia F, Iyori M, Emran TB, Yamamoto DS, Genshi K, Otsuka H, One Y, Yusuf Y, Islam A, Yoshida S. Parasite Immunology e12624 2019/03/18 
  •  Down‐selecting circumsporozoite protein‐based malaria vaccine: a comparison of malaria sporozoite challenge model Yusuf Y, Yoshii T, Iyori M, Yoshida K, Mizukami H, Fukumoto S, Yamamoto DS, Alam A, Emran TB, Amelia F, Islam A, Otsuka H, Takashima E, Tsuboi T, Yoshida S. Frontiers in Immunology 10 730 2019/03/19 
  •  Baculovirus-Induced Fast-Acting Innate Immunity Kills Liver-Stage Plasmodium. Emran TB, Iyori M, Ono Y, Amelia F, Yusuf Y, Islam A, Alam A, Tamura M, Ogawa R, Matsuoka H, Yamaoto DS, Yoshida S. The Journal of Immunology 201 8 2441 2018/10/15 

show all

  •  Anopheline antiplatelet protein from mosquito saliva regulates blood feeding behavior. Islam A, Emran TB, Yamamoto DS, Iyori M, Amelia F, Yusuf Y, Yamaguchi R, Alam MS, Silveira H, Yoshida S. Scientific Reports 9 1 3129 2019/02/28 
  •  Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model. Yoshida K, Iyori M, Blagborough AM, Dulal P, Sala KA, Yamamoto DS, Janse CJ, Biswas S, Yoshii T, Yusuf Y, Tokoro M, Hill AVS, YoshidaS. Scientific Reports 8 1 3896 2018/03/01 
  •  Protective efficacy of an IL-12-expressing baculoviral malaria vaccine. M. Iyori, A.M. Blagborough, K.A Sala, H. Nishiura, K. Takagi, S. Yoshida. Parasite Immunology 39 12 e12498 2017/12/01
  •  DAF-shielded baculovirus-vectored vaccine enhances protection against malaria sporozoite challenge in mice. M. Iyori, D.S. Yamamoto, M. Sakaguchi, M. Mizutani, S. Ogata, H. Nishiura, T. Tamura, H. Matsuoka, S. Yoshida. Malaria Journal 16 1 390 2017/09/29
  •  Development of a Plasmodium berghei transgenic parasite expressing the full-length Plasmodium vivax circumsporozoite VK247 protein for testing vaccine efficacy in a murine model. Mizutani M, Fukumoto S, Soubeiga AP, Soga A, Iyori M, Yoshida S. Malaria Journal 15 251 2016/04/30

Conference Presentations

  • The mechanism of PfCSP-based malaria vaccines and its application to the viral vectored vaccine platform.(conference:17th International Congress of Immunology)(2019/10/23)
  • Full-length Plasmodium falciparum circumsporozoite protein administrated with Imject Alum elicits complete protection in mice against the transgenic P. berghei sporozoites.(conference:PROTEIN ISLAND MATSUYAMA 2019 )(2019/09/10)
  • Protective efficacy for rodent malaria by active immunization of anopheles salivary proteins.(2017/04/16)
  • The Chemical Genetics Study targeting to Anopheline Salivary Protein(2016/09/21)
  • Vectored PfCSP Vaccines based on Baculovirus Dual Expression System and AdHu5 induce Strong Protective Efficacy against Transgenic Plasmodium berghei(conference:American society of tropical medicine & hygiene (ASTMH) 65th Annual Meeting)(2016/11/13)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「ヘテロローガス・プライムブースト免疫法を用いた新規ワクチンプラットフォームの開発」(2018-2020) 
○「肝臓期マラリア原虫に対するバキュロウイルス自然免疫応答による殺傷メカニズム解析」(2019-2021) 
○「プリマキンに替わる抗マラリア自然免疫賦活化薬の開発」(2018-2019) 
○「免疫応答を制御するバキュロウイルスを用いたマラリアワクチンプラットフォームの開発」(2014-2016)

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Introduction to Life Science(2019)
○Freshman Seminar I(2019)
○Host Defense(2019)
○Advanced Molecular Cell Biology(2019)
○Experiments in Biology 1(2019)
○Laboratory Rotation 3(2019)
○Host Defense(2018)
○Advanced Molecular Cell Biology(2018)
○Experiments in Biology 1(2018)
○Laboratory Rotation 2(2018)
○Experiments in Biology 1(2017)
○Advanced Molecular Cell Biology(2017)
○Host Defense(2017)
○Laboratory Rotation(2017)
○Host Defense(2016)
○Advanced Molecular Cell Biology(2016)
○Experiments in Biology 1(2016)
○Freshman Seminar I(2016)

Classes (Graduate Schools)

○Advanced Seminar on Biopharmaceutical Sciences(2019)
○Research Ethics(2019)
○Introduction to Researchers(2019)
○Applied Protein Science(2019)
○Fostering the Independence of Researchers(2019)
○Fostering the Independence of Researchers(2019)
○Experimental Techniques in Biopharmaceutical Sciences(2019)
○Introduction to Biopharmaceutical Sciences(2019)
○Introduction to Biopharmaceutical Sciences(2018)
○Advanced Seminar on Biopharmaceutical Sciences(2018)
○Pharmaceutical Research Practice II(2018)
○Pharmaceutical Sciences Practice II(2018)
○Experimental Techniques in Biopharmaceutical Sciences(2018)
○Applied Protein Science(2017)
○Introduction of Vaccinology(2017)
○Regulation of Protein Function(2017)
○Advanced Seminar on Biopharmaceutical Sciences(2017)
○Biology of Cancer(2017)
○Bio-Functional Analytical Science(2017)
○Experimental Techniques in Biopharmaceutical Sciences(2017)
○Introduction to Biopharmaceutical Sciences(2017)
○Introduction to Pharmaceutical Sciences(2016)
○Biology of Cancer(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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