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Researcher Information

last modified:2021/09/18

Professor ANDO Hitoshi

Mail Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences Department of Cellular and Molecular Function Analysis
Professor

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Graduate School of Phamateutical Sciences
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of Cellular and Molecular Function Analysis

Academic Background

【Degree】
MD

Career

Kanazawa University(2007/04-2008/02)
Jichi Medical University(2008/03-2009/01)
Jichi Medical University(2009/02-2016/03)

Year & Month of Birth

1969/12

Academic Society






Award



Specialities

Applied pharmacology

Speciality Keywords

Research Themes

Elucidation of the mechanisms underlying the association between impaired circadian clock and the development of lifestyle-related diseases, and the development of therapeutic agents

Books

Papers

  •  Brown adipocyte-specific knockout of Bmal1 causes mild but significant impairment of thermogenesis in mice. Nazmul Hasan,Naoto Nagata,Jun-Ichi Morishige,Md Tarikul Islam,Zheng Jing,Ken-Ichi Harada,Mieda Michihiro,Masanori Ono,Hiroshi Fujiwara,Takiko Daikoku,Tomoko Fujiwara,Yoshiko Maida,Tsuguhito Ota,Shigeki Shimba,Shuichi Kaneko,Akio Fujimura,Hitoshi Ando Molecular metabolism 101202 2021/03/03
  •  Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma. Okubo H, Ando H, Ishizuka K, Kitagawa R, Okubo S, Saito H, Kokubu S, Miyazaki A, Ikejima K, Shiina S, Nagahara A. PLoS One 15 3 e0229772 2020/03/03
  •  Influence of renal ischaemia-reperfusion injury on renal neutrophil gelatinase-associated lipocalin receptor (24p3R) in rats. Arakawa Y, Ushijima K, Tsuchiya H, Morishige JI, Mii A, Ando H, Tsuruoka SI, Fujimura A. Clin Exp Pharmacol Physiol 46 12 1166-1173 2019/12/01
  •  Induction of Dbp by a histone deacetylase inhibitor is involved in amelioration of insulin sensityvity via adipocyte differentiation in ob/ob mice. Suzuki C, Ushijima K, Ando H, Kitamura H, Horiguchi M, Akita T, Yamashita C, Fujimura A Chronobiol Int 36 955-968 2019/07/01
  •  Plasma concentration and efficacy of tolvaptan in cirrhotic patients with refractory ascites. Sagawa E, Okubo H, Ando H, Sorin Y, Kanazawa R, Nakadera E, Fukada H, Kokubu S, Miyazaki A. J Pharmacol Sci 2019/02/27

show all

  •  Serum concentration of the CKD4/6 inhibitor abemaciclib, but not of creatinine, strongly predicts hematological adverse events in patients with breast cancer: a preliminary report. Akimitsu Maeda,Kei Irie,Naoya Hashimoto,Shoji Fukushima,Hitoshi Ando,Akira Okada,Hiromichi Ebi,Masaki Kajita,Hiroji Iwata,Masataka Sawaki Investigational new drugs 39 1 272 2021/02
  •  Associations among regorafenib concentrations, severe adverse reactions, and ABCG2 and OATP1B1 polymorphisms. Maeda A, Irie K, Ando H, Hasegawa A, Taniguchi H, Kadowaki S, Muro K, Tajika M, Aoki M, Inaguma K, Kajita M, Fujimura A, Fukushima S. Cancer Chemother Pharmacol 83 107-113 2019/01/01
  •  Social participation and physical prefrailty in older Japanese adults: The Shimane CoHRE study. Takafumi Abe,Kenta Okuyama,Masamitsu Kamada,Shozo Yano,Yuta Toyama,Minoru Isomura,Toru Nabika,Naoki Sakane,Hitoshi Ando,Ryo Miyazaki PloS one 15 12 e0243548 2020
  •  Adolescent Dietary Habit-induced Obstetric and Gynecologic Disease (ADHOGD) as a New Hypothesis-Possible Involvement of Clock System. Tomoko Fujiwara,Masanori Ono,Michihiro Mieda,Hiroaki Yoshikawa,Rieko Nakata,Takiko Daikoku,Naomi Sekizuka-Kagami,Yoshiko Maida,Hitoshi Ando,Hiroshi Fujiwara Nutrients 12 5 2020/05/02
  •  Time restriction of food intake during the circadian cycle Is a possible reegulator of reproductive function in postadolescent female rats. Fujiwara T, Nakata R, Ono M, Mieda M, Ando H, Daikoku T, Fujiwara H. Curr Dev Nutr 3 4 nzy093 2018/11/26
  •  Development and initial validation of the Morningness-Eveningness Exercise Preference Questionnaire (MEEPQ) in Japanese university students. Miyazaki R, Ando H, Hamasaki T, Higuchi Y, Oshita K, Tashiro T, Sakane N. PLoS One 13 e0200870 2018/07/18
  •  Plasma concentration and efficacy of tolvaptan in cirrhotic patients with refractory ascites. Sagawa E,Okubo H,Ando H,Sorin Y,Kanazawa R,Nakadera E,Fukada H,Kokubu S,Miyazaki A J Pharmacol Sci 139 4 373 2019
  •  Pulmonary administration of curcumin inhibits B16F10 melanoma lung metastasis and invasion in mice. Shimada K, Ushijima K, Suzuki C, Horiguchi M, Ando H, Akita T, Shimamura M, Fujii J, Yamashita C, Fujimura A. Cancer Chemother Pharmacol 82 265-273 2018/06/04
  •  Associations among regorafenib concentrations, severe adverse reactions, and ABCG2 and OATP1B1 polymorphisms. Maeda A,Irie K,Ando H,Hasegawa A,Taniguchi H,Kadowaki S,Muro K,Tajika M,Aoki M,Inaguma K,Kajita M,Fujimura A,Fukushima S Cancer Chemother Pharmacol 83 107 2019
  •  Chronotherapy of maxacalcitol on skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate in mice. Yoshioka D, Ando H, Ushijima K, Kumazaki M, Fujimura A. Chronobiol Int 35 9 1269-1280 2018/05/18
  •  Gadoxetic acid-enhanced magnetic resonance imaging to predict paritaprevir-induced hyperbilirubinemia during treatment of hepatitis C. Okubo H, Ando H, Sorin Y, Nakadera E, Fukada H, Morishige J, Miyazaki A, Ikejima K. PLoS One 13 e0196747 2018/04/30
  •  Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study. Tsuchiya Y, Ushijima K, Noguchi T, Okada N, Hayasaka JI, Jinbu Y, Ando H, Mori Y, Kusama M, Fujimura A. Chronobiol Int 35 289-294 2018/02/01
  •  Differences in urinary renal failure biomarkers in cancer patients initially treated with cisplatin. Maeda A, Ando H, Ura T, Muro K, Aoki M, Saito K, Kondo E, Takahashi S, Ito Y, Mizuno Y, Fujimura A. Anticancer Res 37 5235-5239 2017/09/01
  •  Dosing-time-dependent effect of rivaroxaban on coagulation activity in rats. Fujiwara Y, Ando H, Ushijima K, Horiguchi M, Yamashita C, Fujimura A. J Pharmacol Sci 134 234-238 2017/08/12
  •  Prevention against renal damage in rats with subtotal nephrectomy by sacubitril/valsartan (LCZ696), a dual-acting angiotensin receptor-neprilysin inhibitor. Ushijima K, Ando H, Arakawa Y, Aizawa K, Suzuki C, Shimada K, Tsuruoka SI, Fujimura A. Pharmacol Res Perspect 5 e00336 2017/08/01
  •  Association between ABCG2 and SLCO1B1 polymorphisms and adverse drug reactions to regorafenib: a preliminary study. Maeda A, Ando H, Ura T, Komori A, Hasegawa A, Taniguchi H, Kadowaki S, Muro K, Tajika M, Kobara M, Matsuzaki M, Hashimoto N, Maeda M, Kojima Y, Aoki M, Kondo E, Mizutani A, Fujimura A. Int J Clin Pharmacol Ther 55 409-415 2017/05/01
  •  Effect of a dosing-time on quetiapine-induced acute hyperglycemia in mice. Kapse S, Ando H, Fujiwara Y, Suzuki C, Ushijima K, Kitamura H, Hosohata K, Kotani K, Shimba S, Fujimura A. J Pharmacol Sci 133 139-145 2017/02/17
  •  The Effect of Treatments for Rheumatoid Arthritis on Endothelial Dysfunction Evaluated by Flow-Mediated Vasodilation in Patients with Rheumatoid Arthritis. Kotani K, Miyamoto M, Ando H. Curr Vasc Pharmacol 15 1 10-18 2017/01/01
  •  Gadoxetic Acid-Enhanced MR Imaging Predicts Simeprevir-Induced Hyperbilirubinemia During Hepatitis C Virus Treatment: A Pilot Study. Okubo H, Kitamura T, Ando H, Fukada H, Igusa Y, Kokubu S, Miyazaki A, Fujimura A, Shiina S, Watanabe S. J Clin Pharmacol 57 369-375 2016/09/22
  •  Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma. Hosohata K, Washino S, Kubo T, Natsui S, Fujisaki A, Kurokawa S, Ando H, Fujimura A, Morita T. Toxicology 359-360 71-75 2016/06/01
  •  Influence of genetic polymorphisms of multidrug and toxin extrusion protein 1 on its mRNA expression in peripheral blood cells. Ando H, Nakano K, Ushijima K, Kurokawa S, Washino S, Hosohata K, Morita T, Fujimura A. J Pharmacol Sci 131 2 138-140 2016/06/01
  •  Daily Fasting Blood Glucose Rhythm in Male Mice: A Role of the Circadian Clock in the Liver. Ando H, Ushijima K, Shimba S, Fujimura A. Endocrinology 157 2 463-469 2016/02/01
  •  Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake. Hosohata K, Yoshioka D, Tanaka A, Ando H, Fujimura A. Hypertens Res 39 1 19-26 2016/01/01

Conference Presentations

  • Disruption of circadian clocks and metabolic diseases(conference:The 1st Tufts University-Kanazawa University Joint Symposium)(2016/12/13)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○2023「概日リズムに基づく妊娠・産褥期セルフケアプログラムの開発-光と食による制御の検討」(2020-2023) 
○2021「がん自然発症マウスを用いた末梢概日リズム異常によるがん発生・進展誘導機構の解析」(2020-2021) 
○「褐色脂肪細胞における熱産生リズムの形成機構解明と制御法の開発」(2018-2020) 
○「摂食リズムの非同期による時計遺伝子の記憶が誘発する女性生殖機能異常の総合的解析」(2019-2021) 
○「概日リズムによる子宮収縮制御機構に着目した産婦人科疾患予防法の探索」(2019-2021) 
○「末梢体内時計障害の病態生理学的意義の解明と治療法の開発」(2015-2017) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Pharmacology(2019)
○Pharmacology(2018)
○Presentation and Debate (Freshman Seminar II)(2018)
○Presentation and Debate (Freshman Seminar II)(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Pharmacology(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Pharmacology(2016)

Classes (Graduate Schools)

○Molecular Function Analysis(2019)
○Medical Sciences(2019)
○Bio-Ethics(2019)
○The Human Body in Health and Disease Curriculum 1(2019)
○Bio-Ethics(2019)
○The Human Body in Health and Disease Curriculum 1(2019)
○Molecular Function Analysis(2019)
○Introduction to Basic Medical Science(2018)
○Bio-Ethics(2018)
○Medical Sciences(2018)
○Molecular Function Analysis(2018)
○Bio-Ethics(2018)
○Molecular Function Analysis(2018)
○Molecular Function Analysis(2017)
○Molecular Function Analysis(2017)
○Molecular Function Analysis(2017)
○Introduction to Basic Medical Science(2016)
○Molecular Function Analysis(2016)
○Molecular Function Analysis(2016)
○Molecular Function Analysis(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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