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Researcher Information

last modified:2024/03/29

Associate Professor MURAKOSHI, Michio

Mail Laboratory Website

Faculty, Affiliation

Faculty of Frontier Engineering,Institute of Science and Engineering

College and School Educational Field

Graduate School of Natural Science and Technology
Division of Mechanical Science and Engineering, Graduate School of Natural Science and Technology
Division of Mechanical Science and Engineering, Graduate School of Natural Science and Technology
School of Frontier Engineering, College of Science and Engineering

Laboratory

Laboratory of Biomechanical Engineering

Academic Background

【Academic background(Doctoral/Master's Degree)】
Tohoku University Doctor Department of Bioengineering and Robotics, Graduate School of Engineering 200803 Completed
Tohoku University Master Department of Bioengineering and Robotics, Graduate School of Engineering 200503 Completed
【Academic background(Bachelor's Degree)】
Tohoku University Department of Mechatronics and Precision Engineering 200303
【Degree】
PhD

Career

Kanazawa University Institute of Science and Engineering(2019/03-)
Kagoshima University Department of Mechanical Engineering Associate Professor(2015/04-2019/03)
Japan Science and Technology Agency (JST) Researcher, PRESTO(2013/10-2017/03)
Kagoshima University Department of Mechanical Engineering, Graduate School of Science and Engineering Associate Professor(2013/04-2015/03)
The University of Queensland (Brisbane, Australia) Visiting Scholar(2010/07-2010/09)
Tohoku University Department of Bioengineering and Robotics, Graduate School of Engineering Assistant Professor(2009/10-2013/03)
A&D Company, Limited(2008/04-2009/09)
Japan Society for the Promotion of Science (JSPS) Research Fellowship for Young Scientists (DC2)(2007/04-2008/03)

Year & Month of Birth

1980/09

Academic Society

The Japan Society of Mechanical Engineers (JSME)
The Japanese Society for Medical and Biological Engineering (JSMBE)
The Association for Research in Otolaryngology
JAPAN OTOLOGICAL SOCIETY
JAPAN AUDIOLOGICAL SOCIETY
ACOUSTICAL SOCIETY OF JAPAN
International Society of Biomechanics
IAESTE JAPAN
Japan Society of Pediatric ORL

Award

○JSME Medal for Outstanding Paper(2023/03)
○2021 JBSE Papers of the Year Award(2022/06)
○The 25th Seguchi Award (BED, JMSE)(2017/01)
○Young Researchers Award (JSMBE)(2012/05)
○Young Investigators Award (M. Ishida Foundation)(2011/12)
○JSME Young Engineers Award(2008/04)

Specialities

Biomedical engineering/Biomaterial science and engineering、Dynamics/Control、Otorhinolaryngology

Speciality Keywords

Mechanics,Audiology,Otology,Dynamics,Bioengineering,Biomechanics,Motor protein,Hearing

Research Themes

Study on hereditary hearing loss

Study on the motor protein prestin

Study on newborn hearing screening (NHS)

Books

  •  Murakoshi M,Muraoka T Molecular technology for membrane functionalization. In: H. Yamamoto and T. Kato (Eds.), Molecular Technology: Life Innovation Wiley 2018/08/01
  •  Murakoshi M,Kumano S,Ishihara K,Iida K,Hamana H,Koyama S,Wada H Challenges in research on auditory mechanics. In: T. Yamaguchi (Ed.), Nano-Biomedical Engineering 2012 Imperial College Press 2012/02/01
  •  Murakoshi M,Zhao F,Wada H Current developments in the clinical application of the sweep frequency impedance (SFI) in assessing middle ear dysfunction. In: J. Kei and F. Zhao (Eds.), Assessing Middle Ear Function in Infants Plural Publishing 2012/02/01
  •  Wada H,Murakoshi M,Iida K,Kumano S,Ishihara K Inner ear biomechanics. In: T. Yamaguchi (Ed.), Nano-biomedical engineering 2009 World Scientific Publishing 2009/02/01
  •  Wada H,Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T Structural analysis of the motor protein prestin. In: H. Wada (Ed.), Biomechanics at Micro- and Nanoscale Levels Vol. IV World Scientific Publishing 2007/09/01

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  •  Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Kobayashi T,Wada H Protection of outer hair cells from traumatic noise by conditioning with heat stress. In: M. Esashi, K. Ishii, N. Ohuchi, N. Ohsumi, M. Sato and T. Yamaguchi (Eds.), Future Medical Engineering Based on Bionanotechnology Imperial College Press 2006/11/01
  •  Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Generation of stable Chinese hamster ovary cell lines expressing the motor protein prestin. In: M. Esashi, K. Ishii, N. Ohuchi, N. Ohsumi, M. Sato and T. Yamaguchi (Eds.), Future Medical Engineering Based on Bionanotechnology Imperial College Press 2006/11/01
  •  Wada H,Iida K,Kumano S,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T Heterogeneous expression of the motor protein prestin of cochlear outer hair cells. In: H. Wada (Ed.), Biomechanics at Micro- and Nanoscale Levels Vol. II World Scientific Publishing 2006/04/01
  •  Wada H,Sugawara M,Kimura K,Ishida Y,Gomi T,Murakoshi M,Katori Y,Kakehata S,Ikeda K,Kobayashi T Imaging and mechanical properties of guinea pig outer hair cells studied by atomic force microscopy. In: H. Wada (Ed.), Biomechanics at Micro- and Nanoscale Levels Vol. I World Scientific Publishing 2005/01/01

Papers

  •  Wideband frequency impedance for diagnosis of ossicular chain abnormality Sugimoto H,Toya T,Watanabe Y,Takei W,Nagai R,Donjo Y,Motoo R,Inaba M,Yoshizaki T,Murakoshi M Acta Oto-Laryngologica 143 11-12 958 2023/12/02 
  •  Towards non-invasive diagnosis system for middle-ear dysfunctions based on principles of impulse response measurement Toya T,Nagai R,Sugimoto H,Murakoshi M Proceedings of the IEEE 12th Global Conference on Consumer Electronics (GCCE), October 10-13, 2023, Nara, Japan 433 2023/10
  •  Effects of salicylate derivatives on localization of p.H723R allele product of SLC26A4. Murakoshi M,Koike Y,Koyama S,Usami S,Kamiya K,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N,Ishihara K,Wada H Auris Nasus Larynx 49 928 2022/12
  •  Analysis of membrane structure of the inner ear motor protein prestin by force spectroscopy Murakoshi M,Wada H Journal of Biomechanical Science and Engineering 16 3 21 2021/09/15 
  •  Longitudinal changes in dynamic characteristics of neonatal external and middle ears Kanka N,Murakoshi M,Hamanishi S,Kakuta R,Matsutani S,Kobayashi T,Wada H International Journal of Pediatric Otorhinolaryngology 134 110061 2020/04/22 

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  •  Predictive accuracy of sweep frequency impedance technology in identifying conductive conditions in newborns Aithal V,Kei J,Driscoll C,Murakoshi M,Wada H Journal of the American Academy of Audiology 29 106 2018/02/01
  •  Analysis by sweep frequency impedance (SFI) meter of 226-Hz and 1,000-Hz tympanometries in neonates Murakoshi M,Sano K,Kanka N,Yoshida N,Hamanishi S,Kiyokawa H,Kakuta R,Aithal S,Aithal V,Kei J,Driscoll C,Swanston A,Matsutani S,Kobayashi T,Wada H Procedia IUTAM 24 5 2017/08/30
  •  Analysis by finite element method of dynamic characteristics of the external ear canal in neonates Murakoshi M,Takeda S,Wada H Journal of Biomechanical Science and Engineering 12 2 16-00596 2017/06/09
  •  Sweep frequency impedance measures in young infants: developmental characteristics from birth to 6 months Aithal V,Kei J,Driscoll C,Murakoshi M,Wada H International Journal of Audiology 56 3 154 2017/03/01
  •  Effects of ear canal static pressure on the dynamic behaviour of outer and middle ear in newborns Aithal V,Kei J,Driscoll C,Murakoshi M,Wada H International Journal of Pediatric Otorhinolaryngology 82 64 2016/03/01
  •  All three rows of outer hair cells are required for cochlear amplification Murakoshi M,Suzuki S,Wada H BioMed Research International 2015 727434 1 2015/08/01
  •  Sweep frequency impedance measures in Australian aboriginal and Caucasian neonates Aithal V,Kei J,Driscoll C,Swanston A,Roberts K,Murakoshi M,Wada H International Journal of Pediatric Otorhinolaryngology 79 7 1024 2015/07/01
  •  Coordinated movement of three rows of outer hair cells is essential for cochlear amplification Murakoshi M,Suzuki S,Wada H Proceedings of the 12th International Mechanics of Hearing Workshop, June 23-29, 2014, Sounio, Greece 110 2014/06/23
  •  Normative sweep frequency impedance measures in healthy neonates Aithal V,Kei J,Driscoll C,Swanston A,Roberts K,Murakoshi M,Wada H Journal of the American Academy of Audiology 25 4 343 2014/04/01
  •  Dynamic characteristics of the middle ear in neonates Murakoshi M,Yoshida N,Sugaya M,Ogawa Y,Hamanishi S,Kiyokawa H,Kakuta R,Yamada M,Takahashi R,Tanigawara S,Matsutani S,Kobayashi T,Wada H International Journal of Pediatric Otorhinolaryngology 77 4 504 2013/04
  •  Prestin binding peptides as ligands for targeted polymersome mediated drug delivery to outer hair cells in the inner ear Surovtseva EV,Johnston AH,Zhang W,Zhang Y,Kim A,Murakoshi M,Wada H,Newman TA,Zou J,Pyykko I International Journal of Pharmaceutics 424 1月2日 121 2012/03/01
  •  Analysis of membrane topology of prestin expressing in CHO cells Murakoshi M,Kawase T,Kumano S,Wada H Proceedings of the 11th International Mechanics of Hearing Workshop, July 16-22, 2011, Williamstown, MA, USA 533 2011/07/16
  •  High-resolution AFM imaging of prestin purified and reconstituted into an artificial lipid bilayer Wada H,Kumano S,Murakoshi M,Iida K,Hamana H Proceedings of the 11th International Mechanics of Hearing Workshop, July 16-22, 2011, Williamstown, MA, USA 549 2011/07/16
  •  Salicylate restores transport function and anion exchanger activity of missense pendrin mutations Ishihara K,Okuyama S,Kumano S,Iida K,Hamana H,Murakoshi M,Kobayashi T,Usami S,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N,Wada H Hearing Research 270 1-2 110 2010/12/01
  •  Recovery by salicylate of the plasma membrane expression of prestin mutants Wada H,Kumano S,Murakoshi M,Iida K,Ishihara K,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T Proceedings of the 6th World Congress on Biomechanics, August 1-6, 2010, Singapore - 2010/08/01
  •  Atomic force microscopy imaging of the structure of the motor protein prestin reconstituted into an artificial lipid bilayer Kumano S,Murakoshi M,Iida K,Hamana H,Wada H FEBS Letters 584 13 2872 2010/07/01
  •  Salicylate-induced translocation of prestin having mutation in the GTSRH sequence to the plasma membrane Kumano S,Iida K,Ishihara K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H FEBS Letters 584 11 2327 2010/06/01
  •  Mutation-induced reinforcement of prestin-expressing cells Kumano S,Tan X,He DZ,Iida K,Murakoshi M,Wada H Biochemical and Biophysical Research Communications 389 4 569 2009/11/01
  •  Atomic force microscopy in studies of the cochlea Murakoshi M,Wada H Methods in Molecular Biology 493 401 2009/10/28
  •  Immune atomic force microscopy of prestin-transfected CHO cells using quantum dots Murakoshi M,Iida K,Kumano S,Wada H Pflügers Archiv - European Journal of Physiology 457 4 885 2009/02/01
  •  Functional expression of prestin, the outer hair cell motor protein, using the baculovirus/insect cell system Tadenuma T,Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kobayashi T,Kumagai I,Wada H Journal of Biomechanical Science and Engineering 3 2 287 2008/09/01 
  •  Purification of the motor protein prestin from Chinese hamster ovary cells stably expressing prestin Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kobayashi T,Kumagai I,Wada H Journal of Biomechanical Science and Engineering 3 2 221 2008/09/01 
  •  Increase in the activity by mutation of the motor protein prestin Kumano S,Iida K,Murakoshi M,Wada H,Tsumoto K,Ikeda K,Kobayashi T,Kumagai I Proceedings of the 10th International Workshop on the Mechanics of Hearing, July 27-31, 2008, Keele, UK 347 2008/07/27
  •  Assessment of the activity of purified prestin and the effect of salicylate on prestin-chloride biding studied by isothermal titration calorimetry Iida K,Murakoshi M,Kumano S,Wada H,Tsumoto K,Ikeda K,Kobayashi T,Kumagai I Proceedings of the 10th International Workshop on the Mechanics of Hearing, July 27-31, 2008, Keele, UK 344 2008/07/27
  •  Topological characterization by atomic force microscopy of prestin in the plasma membrane of prestin-transfected Chinese hamster ovary cells using quantum dots Murakoshi M,Iida K,Kumano S,Wada H Proceedings of the 10th International Workshop on the Mechanics of Hearing, July 27-31, 2008, Keele, UK 95 2008/07/27
  •  Effects of heat stress on filamentous actin and prestin of outer hair cells in mice Kitsunai Y,Yoshida N,Murakoshi M,Iida K,Kumano S,Kobayashi T,Wada H Brain Research 1177 - 47 2007/10/01
  •  Prevention of noise-induced hearing loss by cochlear mechanism actuated by heat stress Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Proceedings of the 2nd Tohoku-NUS Joint Symposium on the Future Nano-medicine and Bioengineering in the East Asian Region as the 8th International Symposium of Future Medical Engineering Based on Bio-nanotechnology, December 4-5, 2006, Singapore 72 2006/12/04
  •  Imaging by atomic force microscopy of the plasma membrane of prestin-transfected Chinese hamster ovary cells Murakoshi M,Gomi T,Iida K,Kumano S,Tsumoto K,Kumagai I,Ikeda K,Kobayashi T,Wada H Journal of the Association for Research in Otolaryngology 7 3 267 2006/09/01
  •  Analysis of the dynamic behavior of the inner hair cell stereocilia by the finite element method Matsui T,Nkajima C,Yamamoto Y,Andoh M,Iida K,Murakoshi M,Kumano S,Wada H JSME International Journal, Series C 49C 3 828 2006/09/01 
  •  Effects of heat stress on Young's modulus of outer hair cells in mice Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Brain Research 1107 1 121 2006/08/01
  •  Local mechanical properties of mouse outer hair cells: atomic force microscopic study Murakoshi M,Yoshida N,Iida K,Kumano S,Kobayashi T,Wada H Auris Nasus Larynx 33 2 149 2006/06/01 
  •  An apparatus for diagnosis of ossicular chain mobility in humans Koike T,Murakoshi M,Hamanishi S,Yuasa Y,Yuasa R,Kobayashi T,Wada H International Journal of Audiology 45 2 121 2006/02/01
  •  Effects of mutation in the conserved GTSRH sequence of the motor protein prestin on its characteristics Kumano S,Iida K,Murakoshi M,Naito N,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H JSME International Journal, Series C 48C 4 403 2005/12/01 
  •  Atomic force microscopic imaging of the intra cellular membrane surface of prestin-expressing Chinese hamster ovary cells Wada H,Murakoshi M,Iida K,Kumano S,Gomi T,Kimura K,Usukura H,Sugawara M,Kakehata S,Ikeda K,Katori Y,Kobayashi T Proceedings of the 9th Mechanics of Hearing Workshop, July 23-28, 2005, Portland, Oregon, USA - 2005/07/23
  •  Heat stress-induced changes in the mechanical properties of mouse outer hair cells Murakoshi M,Yoshida N,Iida K,Kumano S,Kobayashi T,Wada H Proceedings of the 9th Mechanics of Hearing Workshop, July 23-28, 2005, Portland, Oregon, USA 437 2005/07/23
  •  Mechanical properties of outer hair cell in heat-stressed mice -atomic force microscopy study- Murakoshi M,Yoshida N,Kobayashi T,Wada,H N. I. Ivanov and M. J. Crocker (Eds.), Proceedings of the 11th International Congress on Sound and Vibration, July 5-8, 2004, St. Petersburg, Russia 3005 2004/07/05
  •  Development of an apparatus for diagnosis of ossicular chain mobility Wada H,Koike T,Murakoshi M,Yuasa R,Yuasa Y,Honda N,Goode RL Proceedings of the 3rd Symposium on Middle Ear Mechanics in Research and Otology, July 9-12, 2003, Matsuyama, Japan 440 333 2003/07/09

Conference Presentations

  • The Past and Future of Middle Ear Function Assessment Devices(conference:Panel Discussion 3, The 33rd Annual Meeting of the Japan Otological Society, November 1-4, 2023, Gumma)(2023/11/04)
  • Non-invasive hearing diagnosis, breaking through with dynamics and bioengineering(conference:Yumenavi Live 2023 in Autumn, October 21-22, 2023, Online)(2023/10/21)
  • Can we find conductive hearing loss?(conference:Medtech Academy Pitch Day 2022)(2023/03/03)
  • Development of a diagnostic device for conductive hearing loss applicable to neonates(conference:Sensor & IoT Consortium)(2023/02/27)
  • Recent research on evaluation of auditory function in neonates(conference:Joint Research Meeting of EA, EMM and ASJ-H, The Institute of Electronics, Information and Communication Engineers and the Acoustical Society of Japan, November 21-22, 2022, Online.)(2022/11/21)

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  • Development of a simple non-invasive diagnostic device for conductive hearing loss(conference:healthTECH JAPAN, October 12-14, 2022, Yokohama)(2022/10/12)
  • Development of a simple non-invasive diagnostic device for conductive hearing loss(conference:healthTECH JAPAN, October 12-14, 2022, Yokohama)(2022/10/12)
  • Development of a diagnostic method for conductive hearing loss based on middle ear dynamics(conference:The 67th Congress of Japan Audiological Society, October 5-7, 2022, Yamagata, 186)(2022/10/07)
  • Mechanics of Hearing -From External Auditory Canal to Inner Ear Protein Prestin-(conference:Sectional Committee Meeting and Seminar and Joint WG Meeting, Sectional Committee of Material, Hokuriku Future Co-creation Forum, September 30, 2022, Kanazawa)(2022/09/30)
  • Diagnostic device for conductive hearing loss applicable to neonates(conference:JST New Technology Presentation Meetings, JST, August 18, 2022, Online.)(2022/08/18)
  • Dynamic characteristics of the external and middle ears from neonates to infants and its application to diagnosis of conductive hearing loss(conference:The 17th Annual Meeting of Japan Society for Pediatric ORL, July 21-22, 2022, Toyama)(2022/07/21)
  • Development of diagnostic equipment for conductive hearing loss based on middle ear dynamics(conference:The 61st Annual Conference of the JSMBE, June 28-30, 2022, Nigata)(2022/06/30)
  • Development of a simple non-invasive diagnostic device for conductive hearing loss(conference:Medtech Japan, April 20-22, 2022, Tokyo)(2022/04/22)
  • Research and development on simple non-invasive diagnosis of conductive hearing loss(conference:The 4th Medtec Matching "Development of diagnostic methods using latest technologies by young researchers: application to the fields of cancer, ophthalmology and otolaryngology," AMED and LINK-J, March 28, 2022, online from Tokyo)(2022/03/28)
  • Chronological changes in the external- and middle-ear dynamics in neonates(conference:The 11th Asian-Pacific Conference on Biomechanics (APBiomech 2021), December 2-5, 2021, Online from Kyoto, Japan)(2021/12/03)
  • Development of simple noninvasive diagnostic equipment for conductive hearing loss(conference:The 33rd Bioengineering Conference of the JSME, June 25-26, 2021, Online from Tokyo)(2021/06/25)
  • Mechanics of Hearing and its application(conference:The 5th TT Faculty Lancheon Seminar, Kanazawa University, July 8, 2020, Kanazawa.)(2020/07/08)
  • Effects of rotation of the stereociliary bundles of outer hair cells on the cochlear amplification(conference:The 43rd Annual MidWinter Meeting of the Association for Research in Otolaryngology, January 25-29, 2020, San Jose, California, USA)(2020/01/27)
  • Effects of abnormality of the inner-ear sensory cells on the cochlear amplification(conference:The 32nd Bioengineering Conference of the JSME, December 20-21, 2019, Kanazawa)
  • Membrane topology of inner ear motor protein prestin(conference:The 3rd Thailand-Japan Research Exchange Joint Symposium, KMUTT Knowledge Exchange for Innovation Center (KX), August 21, 2019, Bangkok, Thailand)(2019/08/21)
  • Development of recombinant inner-ear motor protein prestin equipped with affinity tag(conference:The 2019 Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C 2019), June 25-28, 2019, Seven Springs, Pennsylvania, USA)(2019/07/28)
  • Auditory system with mechanical amplifier(conference:The 1st Colloquium of Frontier Engineering, Kanazawa University, July 12, 2019, Kanazawa.)(2019/07/12)
  • The basics of hearing mechanics and its applications(conference:Kanazawa Bioengineering and Composit Meeting, May 18, 2019, Kanazawa)(2019/05/18)
  • Development of a method for recovering the localization anormaly caused by genetic mutation of an anion exchange protein pendrin in the inner ear(conference:The 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama)
  • Analysis of the dynamic behavior of the external and middle ears in neonates from a few days to 6 months after birth(conference:The 63rd Congress of Japan Audiological Society, October 17-19, 2018, Kobe)(2018/10/19)
  • Cochlear amplifier: past, present and future(conference:The 66th Seminoar on Audiological Physiology, Japan Audiological Society, October 18, 2018, Kobe)(2018/10/18)
  • Restoration of proper delivery to the cell membrane for pendrin mutants by salicylate derivatives(conference:The 28th Annual Meeting of the Japan Otological Society, October 3-6, 2018, Osaka)(2018/10/05)
  • Que sera, sera (Whatever will be, will be)(conference:The 1st Shutsuran-kai Meeting, The 29th JSME Conference on Frontiers in Bioengineering, October 24-25, 2018, Chiba)(2018/10/04)
  • Characteristics of the external- and middle-ear dynamics in neonates(conference:The 8th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2018), July 5-9, 2018, Shanghai, China)(2018/07/08)
  • Development of a hearing screening system for newborns(conference:The 57th Annual Conference of the JSMBE, June 19-21, 2018, Sapporo)(2018/06/20)
  • Recent studies on auditory periphery: from external ear canal to prestin, from adults to neonates(conference:The 5th Kyushu-Okinawa Workshop for Assistance of Hearing Impaired People, Audiology and Hearing Implant Center, Department of Otolaryngology, Head & Neck Surgery, Faculty of Medicine, The University of Miyazaki, March 25-26, 2018, Miyazaki)(2018/03/25)
  • Recent studies on evaluation of auditory function for neonates(conference:The Acoustical Society of Japan 2018 Spring Meeting, March 13-15, 2018, Saitama)(2018/03/13)
  • Development of CHO expression systems of recombinant inner-ear motor proteins having different affinity tags(conference:The 30th Bioengineering Conference of the JSME, December 14-15, 2017, Kyoto)
  • Hearing mechanism and its measurement and control(conference:SICE Kyushu Forum 2017, November 24, 2017, Kagoshima)(2017/11/24)
  • Construction of a mammalian cell line stably expressing the inner-ear motor protein prestin(conference:The 62nd Congress of Japan Audiological Society, October 18-20, 2017, Fukuoka)
  • Decipherment of the membrane structure of the inner ear motor protein prestin by force spectroscopy(conference:The 5th Switzerland-Japan Workshop on Biomechanics (SJB2017), September 14-17, 2017, Zermatt, Switzerland)(2017/09/14)
  • Difference in the dynamic behavior of the hearing apparatus between neonates and adults: the effects on tympanometry(conference:The XXVI Congress of the International Society of Biomechanics incorporating the 9th Asian-Pacific Conference on Biomechanics (AP Biomech 2017), July 23-27, 2017, Brisbane, Australia)(2017/07/27)
  • Learn from the mechanics of hearing -From the inner ear tissue to the membrane protein-(conference:The Latest Trend and Development of Application on Molecular Electronics and Bioelectronics, The Seminar on Molecular Electronics and Bioelectronics of the Japan Society of Applied Physics, June 6, 2017, Kita-Kyushu)(2017/06/06)
  • Analysis of neonatal tympanometry using SFI data(conference:IUTAM Symposium on Advances in Biomechanics of Hearing, May 17-20, 2016, Stuttgart, Germany)(2017/05/17)
  • Engineering consideration of hearing and its application(conference:The 3rd Research Meeting 2016 of the Electronics Division, The Kinki Chemical Society Japan, January 16, 2017, Osaka)(2017/01/16)
  • Mechanical understanding of biomembrane molecules and its application to nanobiodevice innovation(conference:The 6th CSJ Chemistry Festa, November 14-16, 2016, Tokyo)(2016/11/16)
  • Mechanism of hearing loss caused by the loss of outer hair cells –FEM analysis–(conference:The 61st Congress of Japan Audiological Society, October 19-21, Morioka, Iwate)(2016/10/21)
  • Coordinating movement of outer hair cells and cochlear amplification(conference:The 11th ERA/OAE Research Meeting of the Japan Audiological Society, July 10, Tokyo)(2016/07/10)
  • Mechanical understanding of biomembrane molecules and its application to nanobiodevice innovation(conference:The 96th Annual Meeting of the Chemical Society of Japan, March 24-27, 2016, Kyoto)(2016/03/24)
  • Development of a mammalian cell expression system of the motor protein prestin expressing in the inner ear(conference:The 28th Bioengineering Conference of the JSME, January 9-10, 2016, Tokyo)(2016/01/09)
  • Sound amplification mechanism by three rows of outer hair cells in mammals(conference:The 8th Asian-Pacific Conference on Biomechanics (AP Biomech 2015), September 16-19, 2015, Sapporo, Japan)(2015/09/19)
  • Changes in dynamic characteristics of the external ear canal wall during the first 3 months of life(conference:The 7th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO 2015), July 1-5, 2015, Aalborg, Denmark)(2015/07/04)
  • Topology of prestin expressed in the CHO cell membrane -atomic force microscopy study-(conference:The 2015 Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C 2015), June 17-20, 2015, Snowbird, Utah, USA)(2015/06/19)
  • Numerical analysis of the elaborate sound amplification mechanism of the mammalian inner ear(conference:The World Congress of Medical Physics and Biomedical Engineering 2015, June 7-12, 2015, Toronto, Canada)
  • Analysis of the dynamic behavior of the auditory system in newborns focused on the external ear-canal deformation(conference:The 54th Annual Conference of the JSMBE, May 7-9, 2015, Nagoya)(2015/05/09)
  • Analysis of middle ear diagnostic tympanometry in neonates(conference:The 27th Bioengineering Conference of the JSME, January 9-10, 2015, Niigata)(2015/01/15)
  • Dynamic behavior of the external and middle ears in neonates(conference:The Kagoshima Meeting of the Kyusyu Branch of the JSME, September 27-28, 2014, Kagoshima)
  • Development of a real-time simulator of the human auditory system for next-generation hearing aid system(conference:The 2014 JSPE Autumn Meeting, September 16, 2014, Tottori)(2014/09/16)
  • Force spectroscopy study on transmembrane structure of the motor protein prestin expressed in the inner ear(conference:The 4th Japan-Switzerland Workshop on Biomechanics, September 1-4, 2014, Shima, Mie)(2014/09/03)
  • Mechanics of hearing–from outer to inner ears –(conference:College of Engineering, San Diego State University (SDSU), August 26, 2014, San Diego, USA)(2014/08/26)
  • Coordinated movement of three rows of outer hair cells is essential for cochlear amplification(conference:The 12th International Mechanics of Hearing Workshop, June 23-29, 2014, Sounio, Greece)(2014/06/26)
  • Chronological changes in dynamic behavior of the hearing system in newborns(conference:The 26th Bioengineering Conference of the JSME, January 11-12, 2014, Sendai)(2014/01/12)
  • Effects of coordinating movement of three-row outer hair cells on the cochlear amplification(conference:Faculty of Science, The University of Rome Tor Vergata, December 6, 2013, Rome, Italy)(2013/12/06)
  • Protective mechanism of the outer hair cells from traumatic noise by prior whole-body heat stress(conference:The 36th Annual MidWinter Meeting of the Association for Research in Otolaryngology, February 16-20, 2013, Baltimore, Maryland, USA)
  • Analysis by using the sweep frequency impedance (SFI) meter of dynamic behavior of hearing system in newborns(conference:The 25th Bioengineering Conference of the JSME, January 9-11, 2013, Tsukuba)(2013/01/10)
  • Conditioning-related protection of sensory cells from acoustic injury(conference:The Biofrontier Symposium 2012 of the JSME, October 5, 2012, Hirosaki)(2012/10/05)
  • Dynamic behavior of the neonatal ear canal: theoretical considerations(conference:The 6th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2012), June 27-July 1, 2012, Daegu, Korea)(2012/06/28)
  • Analysis of ear-canal dynamics in neonates: theoretical considerations(conference:Newborn Hearing Screening (NHS) 2012, June 5-7, 2012, Cernobbio, Italy)(2012/06/06)
  • Analysis of membrane topology of prestin expressing in CHO cells(conference:The 11th International Mechanics of Hearing Workshop, July 16-22, 2011, Williamstown, Massachusetts, USA)
  • Atomic force microscopic analysis of membrane topology of the inner ear motor protein prestin(conference:The 50th Annual Conference of the JSMBE, April 29-May 2, 2011, Tokyo)(2011/04/30)
  • Analysis of transmembrane structure of the inner ear motor protein prestin-atomic force microscopy study-(conference:The 23rd Bioengineering Conference of the JSME, January 8-9, 2011, Kumamoto)
  • The inner ear motor protein prestin –analysis by atomic force microscopy of its structure and function–(conference:Department of Audiology, School of Health and Rehabilitation Sciences, The University of Queensland, September 8, 2010, Brisbane, Australia)(2010/09/08)
  • Analysis of transmembrane structure of prestin by single molecule force spectroscopy(conference:The 47th Inner Ear Biology Workshop, August 29-September 1, 2010, Prague, Czech Republic)
  • Employment of cochlear mechanism actuated by heat stress to prevent noise-induced hearing loss(conference:Audiology Department, The Townsville Hospital, August 17, 2010, Townsville, Australia)(2010/08/17)
  • Single molecule force spectroscopiy of the inner-ear motor protein prestin using an atomic force microscope(conference:The 6th World Congress on Biomechanics, August 1-6, 2010, Singapore)
  • Protective mechanism of the inner ear from traumatic noise exposure actuated by conditioning with heat stress(conference:Department of Audiology, School of Health and Rehabilitation Sciences, The University of Queensland, July 30, 2010, Brisbane, Australia)(2010/07/30)
  • Imuune atomic force Microscopy of the inner ear motor prestin using Qdots(conference:SMART-Tohoku GCOE joint Workshop on Micro & Nano Bioengineering: MIT, NUS, NTU and Tohoku, January 11-12, 2010, Singapore)
  • Atomic force microscopic imaging of the inner ear motor protein prestin using quantum dots(conference:Watching Biomolecules in Action Symposium & 2nd Kanazawa Bio-AFM Workshop, December 14-17, 2009, Osaka, Japan)
  • Visualization by atomic force microscopy of the inner ear motor protein prestin using Qdot(conference:The 43rd Annual Meeting of the Tohoku Branch of the JSMBE, November 21, 2009, Fukushima)
  • Topological characterization by atomic force microscopy of prestin in the plasma membrane of prestin-transfected Chinese hamster ovary cells using quantum dots(conference:The 10th International Workshop on the Mechanics of Hearing, July 27-31, 2008, Keele, UK)
  • Immune atomic force microscopy of the plasma membrane of prestin-transfected Chinese hamster ovary cells using quantum dots(conference:The 31st Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 16-21, 2008, Phoenix, Arizona, USA)
  • Imaging by atomic force microscopy of the motor protein prestin labeled with quantum dots(conference:The 20th Bioengineering Conference of the JSME, January 25-26, 2008, Tokyo)
  • Heat-stress actuated mechanism of the inner ear protecting it from traumatic noise exposure(conference:The 3rd Asian Pacific Conference on Biomechanics, November 5-8, 2007, Tokyo, Japan (Young Investigator Award受賞))
  • Heat-stress actuated protective mechanism of the inner ear against noise-induced hearing loss(conference:The 19th International Congress on Acoustics, September 2-7, 2007, Madrid, Spain)
  • Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress(conference:The Auditory Research Meeting 2007, August 9-10, 2007, Sendai)
  • Prevention of noise-induced hearing loss by cochlear mechanism actuated by heat stress(conference:The Japan-China Conference on Acoustics, June 4-6, 2007, Sendai, Japan)
  • Employment of cochlear mechanism actuated by stress to prevent noise-induced hearing loss(conference:The 9th International Symposium on Future Medical Engineering based on Bio-nanotechnology jointly organized with the 19th Bioengineering Conference, 2006 Annual Meeting of BED/JSME, January 7-9, 2007, Sendai, Miyagi, Japan)
  • Heat stress-induced protection of outer hair cells from traumatic noise exposure(conference:The 19th Bioengineering Conference of the JSME, January 7-8, 2007, Sendai)
  • Employment of cochlear mechanism actuated by stress to prevent noise-induced hearing loss(conference:The 2nd Tohoku-NUS Joint Symposium on the Future Nano-medicine and Bioengineering in the East Asian Region as the 8th International Symposium of Future Medical Engineering Based on Bio-nanotechnology, December 4-5, 2006, Singapore)
  • Heat stress-induced changes in Young's modulus of outer hair cells in mice(conference:The 2nd Shanghai International Conference on Physiological Biophysics-Audition and Vision, November 3-7, 2006, Shanghai, China)
  • Heat stress-induced cochlear protection from acoustic injury(conference:The 9th Western Pacific Acoustics Conference, June 26-28, 2006, Seoul, Korea)
  • Atomic force microscopic observation of the conformational changes in the voltage-dependent motor protein prestin(conference:The 18th Bioengineering Conference of the JSME, January 13-14, 2006, Niigata)
  • Protection of outer hair cells from traumatic noise by prior whole-body heat stress(conference:The 2nd Asian Pacific Conference on Biomechanics, November 23-25, 2005, Taipei, Taiwan (Graduate Student Award受賞))
  • Atomic force microscopic analysis of prestin-transfected CHO cell plasma membranes(conference:The 6th International Symposium on Future Medical Engineering Based on Bio-nanotechnology, November 21, 2005, Sendai, Miyagi, Japan)
  • Changes in structure and mechanical properties of mouse outer hair cells in response to whole-body heat stress(conference:The 2nd Japan-Switzerland Workshop on Biomechanics, September 12-16, 2005, Kyoto, Japan)
  • Heat stress-induced changes in the mechanical properties of mouse outer hair cells(conference:The 9th Mechanics of Hearing Workshop, July 23–28, 2005, Portland, Oregon, USA (Student Travel Awards by the National Institutes of Health (NIH) and Etymotic Research Inc. 受賞))
  • Mechanical property change in outer hair cells caused by whole-body heat stress in mice(conference:The 28th Annual Meeting of the Japanese Society of Biorheology, July 7-8, 2005, Sendai)
  • Imaging of the cytoplasmic face of the prestin-expressing CHO cell membrane by atomic force microscopy(conference:The 28th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 19-24, 2005, New Orleans, Louisiana, USA)
  • Observation of the plasma membrane of the CHO cells expressing the motor protein prestin by atomic force microscopy(conference:The 17th Bioengineering Conference of the JSME, January 22-23, 2005, Nagoya)
  • Effects of heat stress on the mechanical properties of outer hair cells in mice(conference:The 15th JSME Conference on Frontiers in Bioengineering, November 6-7, 2004, Ube)
  • Intraoperative measurement of ossicular mobility(conference:The 17th International Congress of Audiology, September 26-30, 2004, Phoenix, Arizona, USA)
  • Mechanical properties of outer hair cell in heat-stressed mice –atomic force microscopy study–(conference:The 11th International Congress on Sound and Vibration, July 5-8, 2004, St. Petersburg, Russia)
  • Development of an apparatus for diagnosis of ossicular chain mobility in humans(conference:The 14th JSME Conference on Frontiers in Bioengineering, September 18-19, 2003, Zao)

Others

  •  Development of an auditory model for non-invasive intracranial pressure measurement based on middle ear dynamics Tobe K,Murakoshi M Proceedings of the 34th JSME Conference on Frontiers in Bioengineering, December 16-17, 2023, Ube, 1D09 1 2023/12
  •  Laboratory of Biomechanical Engineering, School of Frontier Engineering, Kanazawa University Murakoshi M Kanazawa Kogyokai-shi 203 2 2023/12
  •  Sweep frequency impedance measures of different ear conditions Nakagawa H,Teruki T,Nagai R,Sugimoto H,Murakoshi M Extended Abstract of the 12th Asian Pacific Conference on Biomechanics, November 15-18, 2023, Kuala Lumpur, Malaysia 88 2023/11
  •  Development of planar lipid membranes for analysis of an inner-ear motor protein prestin Niioka H,Murakoshi M Extended Abstract of the 12th Asian Pacific Conference on Biomechanics, November 15-18, 2023, Kuala Lumpur, Malaysia 7 2023/11
  •  The Past and Future of Middle Ear Function Assessment Devices Murakoshi M Proceedings of the 33rd Annual Meeting of the Japan Otological Society, November1-4, 2023, Takasaki, PD3-3 45 45 2023/11

show all

  •  Development of a Simple Non-Invasive Diagnostic Apparatus for Ossicular Chain Abnormalities in the Middle Ear (Follow-up) Sugimoto H,Hasegawa H,Hatano M,Yoshizaki T,Murakoshi M Proceedings of the 33rd Annual Meeting of the Japan Otological Society, November1-4, 2023, Takasaki, O30-5 286 2023/11
  •  Trial of infant hearing screening using the Titan tympanometer Sugimoto H,Toya T,Takei W,Nagai R,Murakoshi M,Yoshizaki T Proceedings of the 18th Annual Meeting of Japan Society for Pediatric ORL, November 9-10, 2023, Beppu, O-71 209 2023/11
  •  Improvement of middle ear impedance meter based on impulse response measurement principle Toya T,Nagai R,Sugimoto H,Murakoshi M Proceedings of the Acoustical Society of Japan 2023 Autumn Meeting, September 26-28, 2023, Nagoya, 1-R-12 877 2023/09
  •  Development of CHO cell lines stably expressing prestin and its functional analysis Motoo R,Donjo Y,Sugimoto H,Yoshizaki T,Murakoshi M Proceedings of the 40th Proceedings of the 40th ENT Neuroscience Research Meeting 2023/08
  •  Sweep frequency impedance (SFI) measures of middle ears with ossicular-chain dysfunctions Toya T,Nakagawa H,Nagai R,Sugimoto H,Murakoshi M Proceedings of the 6th Japan-Switzerland Workshop on Biomechanics, August 29-September 1, 2023, Otaru, Hokkaido, Japan 70 2023/08
  •  Analysis of motor protein prestin using a planar lipid membrane Niioka H,Murakoshi M Proceedings of the 6th Japan-Switzerland Workshop on Biomechanics, August 29-September 1, 2023, Otaru, Hokkaido, Japan 39 2023/08
  •  Sweep frequency impedance measures of normal middle ear Nakagawa H,Toya T,Murakoshi M Proceedings of the 6th Japan-Switzerland Workshop on Biomechanics, August 29-September 1, 2023, Otaru, Hokkaido, Japan 38 2023/08
  •  Sweep frequency impedance (SFI) measures in normal ear Nakagawa H,Toya T,Nagai R,Sugimoto H,Murakoshi M Proceedings of the 35th Bioengineering Conference of the JSME, June 3-4, 2023, Sendai, P312-2 217 2023/06
  •  Analysis of the motor protein prestin using planar lipid membranes Niioka H,Murakoshi M Proceedings of the 35th Bioengineering Conference of the JSME, June 3-4, 2023, Sendai, P107-2 165 2023/06
  •  Proposal of impact reduction supporter for American football Miura K,Urasunai Y,Aoki Y,Murakoshi M,Hagiyama R,Hamanishi S Proceedings of the 35th Bioengineering Conference of the JSME, June 3-4, 2023, Sendai, P202-2 184 2023/06
  •  Distribution of dynamic behavior of ossicles with separation and fixation based on sweep frequency impedance (SFI) Toya T,Nakagawa H,Nagai R,Sugimoto H,Murakoshi M Proceedings of the 35th Bioengineering Conference of the JSME, June 3-4, 2023, Sendai, P313-2 218 2023/06
  •  An example of promotion of medical equipment development from science and engineering research seeds: New middle ear function measurement technology Watanabe Y,Tamai S,Toya T,Nagai R,Takei W,Sugimoto H,Murakoshi M Proceedings of the 14th Annual Meeting of the Japan Society of Clinical Trials and Research, February 9-10, 2023 2023/02
  •  Measurement of dynamic characteristics for several middle-ear conditions based on sweep frequency impedance (SFI) Toya T,Mageshi A,Nakagawa H,Nagai R,Sugimoto H,Murakoshi M Proceedings of the 33rd JSME Conference on Frontiers in Bioengineering, December 17-18, 2022, Kobe, 1C08, 4 pages. 2022/12
  •  Development of a new ear probe for sweep frequency impedance (SFI) meter Kokubo T,Nakagawa H,Toya T,Murakoshi M Proceedings of the 33rd JSME Conference on Frontiers in Bioengineering, December 17-18, 2022, Kobe, 1C18, 4 pages. 2022/12
  •  Development of a diagnostic method for conductive hearing loss based on middle ear dynamics Murakoshi M Proceedings of the 67th Congress of Japan Audiological Society, October 5-7, 2022, Yamagata, 186 501 2022/10
  •  Development of a non-invasive diagnosis device for ossicular abnormalities Sugimoto H,Murakoshi M,Yoshizaki T Proceedings of the 32nd Annual Meeting of the Japan Otological Society, October 19-21, 2022, Yokohama, O1-2 161 2022/10
  •  My Turning Point Michio Murakoshi Bioengineering News, JSME 51 11 2022/09
  •  Dynamic characteristics of the external and middle ears from neonates to infants and its application to diagnosis of conductive hearing loss Murakoshi M,Sugimoto H Proceedings of the 17th Annual Meeting of Japan Society for Pediatric ORL, July 21-22, 2022, Toyama, O-1 85 2022/07
  •  Sweep frequency impedance (SFI) measurements on adults with normal middle ear function Nakagawa H,Mageshi A,Toya T,Murakoshi M Proceedings of the 34th Bioengineering Conference of the JSME, June 25-26, 2022, Fukuoka, 2P5-07 2022/06
  •  Development of a non-invasive method for measuring intracranial pressure (ICP) based on dynamic characteristics of the middle ear Mageshi A,Murakoshi M Proceedings of the 34th Bioengineering Conference of the JSME, June 25-26, 2022, Fukuoka, 2P5-05 2022/06
  •  Measurements of sweep frequency impedance (SFI) for patients with conductive hearing loss Toya T,Mageshi A,Nakagawa H,Nagai R,Sugimoto H,Murakoshi M Proceedings of the 34th Bioengineering Conference of the JSME, June 25-26, 2022, Fukuoka, 2P5-06 2022/06
  •  Cytotoxicity and localization restoring effect for pendrin mutants of salicylate derivatives Koike Y,Murakoshi M Proceedings of the 32nd JSME Conference on Frontiers in Bioengineering, January 12-13, 2022, Online from Nagoya, 1A11 2022/01/12
  •  Development of diagnostic equipment for conductive hearing loss based on middle ear dynamics Murakoshi M,Toya T,Mageshi A,Nakagawa H,Nagai R,Sugimoto H Proceedings of the 61st Annual Conference of the JSMBE, June 28-30, 2022, Niigata, O3-5-2-3 207 2022/06
  •  Development of a Non-invasive Diagnosis Device for Ossicular Abnormalities Sugimoto H,Murakoshi M,Yoshizaki T Proceedings of the 123rd Annual Meeting of the Japanese Society of Otorhinolaryngology-Head and Neck Surgery, May 25-28, 2022, Kobe, 0-206 2022/05
  •  Chronological changes in the external- and middle-ear dynamics in neonates Murakoshi M,Kanka N,Hamanishi S,Wada H Abstract of the 11th Asian-Pacific Conference on Biomechanics (APBiomech 2021), December 2-5, 2021, Online from Kyoto, Japan 226 2021/12/02
  •  Development of simple noninvasive diagnostic equipment for conductive hearing loss Murakoshi M,Mageshi A,Donjo Y,Sugimoto H Proceedings of the 33rd Bioengineering Conference of the JSME, June 25-26, 2021, Online from Tokyo, 1S1-36 64 2021/06/25
  •  Development of an evaluation method for compounds recovering pendrin mutants causing hearing loss Koike Y,Murakoshi M Proceedings of the 60th Annual Conference of the JSMBE, June 15-17, 2021, Online from Kyoto, O2-8-1-5 37 2021/06/15
  •  Laboratory of Biomechanical Engineering, School of Mechanical Engineering/Frontier Engineering, College of Science and Engineering, Kanazawa University; Division of Mechanical Science and Engineering, Graduate School of Natural Science and Technology, Kanazawa University Murakoshi M Bioengineering News, JSME 49 30 2020/09/01
  •  Investigation of chronological changes in dynamic characteristics of neonatal ears using sweep frequency impedance (SFI) technique Kanka N,Murakoshi M,Hamanishi S,Wada H Abstract of the 43rd Annual MidWinter Meeting of the Association for Research in Otolaryngology, January 25-29, 2020, San Jose, California, USA 431 2020/01/25
  •  Effects of rotation of the stereociliary bundles of outer hair cells on the cochlear amplification Murakoshi M,Wada H Abstract of the 43rd Annual MidWinter Meeting of the Association for Research in Otolaryngology, January 25-29, 2020, San Jose, California, USA 397 2020/01/25
  •  Effects of abnormality of the inner-ear sensory cells on the cochlear amplification Murakoshi M,Wada H Proceedings of the 32nd Bioengineering Conference of the JSME, December 20-21, 2019, Kanazawa, 2A22 2p 2019/12/20
  •  Numerical analysis of the effect of rotation of the outer hair cell stereocilia on the cochlear amplification Murakoshi M,Wada H Proceedings of the 29th Annual Meeting of the Japan Otological Society, October 10-12, 2019, Yamagata, O50-3 514 2019/10/10
  •  After the 30th JSME Conference on Frontiers in Bioengineering Murakoshi M Bioengineering News, JSME 48 14 2019/09/01
  •  Development of a new diagnostic device, EarDoc, using tympanometry and SFI technique Kanka N,Murakoshi M,Hamanishi S,Wada H Proceedings of the 30th JSME Conference on Frontiers in Bioengineering, July 19-20, 2019, Kirishima, 1B15 3p 2019/07/19
  •  Development of recombinant inner-ear motor protein prestin equipped with affinity tag Murakoshi M,Wada H Proceedings of the 2019 Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C 2019), June 25-28, 2019, Seven Springs, Pennsylvania, USA 503 2019/06/25
  •  Study on a probe for the diagnostic apparatus of the middle and inner ear using a finite-element method Hamanishi S,Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 2D15 2p 2018/12/14
  •  Construction and evaluation of cell lines stably expressing the His-tagged prestin Yoshida H,Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 2F26 2p 2018/12/14
  •  Development of a wideband frequency impedance meter for neonatal hearing screening (NHS) Yamada K,Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 1D41 2p 2018/12/14
  •  Analysis of the effects of the functional loss of outer hair cells on the dynamic behavior of the organ of Corti Honda F,Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 1E34 2p 2018/12/14
  •  Functional analysis of the motor protein prestin labeled with AviTag Shirai H,Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 2F16 2p 2018/12/14
  •  Development of a method for recovering the localization anormaly caused by genetic mutation of an anion exchange protein pendrin in the inner ear Murakoshi M,Wada H Proceedings of the 31st Bioengineering Conference of the JSME, December 14-15, 2018, Koriyama, 2F34 2p 2018/12/14
  •  Restoration of localization of pendrin mutants causing sensorineural hearing loss by lasalocid sodium Yoshida H,Murakoshi M,Matsuzaki K Proceedings of the 29th JSME Conference on Frontiers in Bioengineering, October 24-25, 2018, Chiba, 2A15 4p 2018/10/24
  •  Numerical analysis of effects of outer hair cell dysfunction on the dynamic behavior of the organ of Corti in the cochlea Honda F,Murakoshi M,Matsuzaki,K Proceedings of the 29th JSME Conference on Frontiers in Bioengineering, October 24-25, 2018, Chiba, 2B11 4p 2018/10/24
  •  Analysis of the dynamic behavior of the external and middle ears in neonates from a few days to 6 months Murakoshi M,Wada H Proceedings of the 63rd Congress of Japan Audiological Society, October 17-19, 2018, Kobe, 196 497 2018/10/17
  •  Restoration of proper delivery to the cell membrane for pendrin mutants by salicylate derivatives Murakoshi M,Wada H Proceedings of the 28th Annual Meeting of the Japan Otological Society, July 3-6, 2018, Osaka, O-161 433 2018/09/12
  •  Numerical analysis for passive dynamic biped walking taking into accout motion in coronal plane Yonekura K,Matsuzaki K,Iiyama H,Murakoshi M Proceedings of the Dynamics and Design Conference 2018, August 8-31, Tokyo - 2018/08/28
  •  Effects of chronological age on neonatal tympanogram with 226-Hz probe tone Kanka N,Murakoshi M,Hamanishi S,Wada H Proceedings of the 8th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2018), July 5-9, 2018, Shanghai, China 111 2018/07/05
  •  Characteristics of the external- and middle-ear dynamics in neonates Murakoshi M,Aithal V,Hamanishi S,Kei J,Wada H Proceedings of the 8th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2018), July 5-9, 2018, Shanghai, China 113 2018/07/05
  •  Development of a hearing screening system for newborns Murakoshi M,Hamanishi S,Wada H Proceedings of the 57th Annual Conference of the JSMBE, June 19-21, 2018, Sapporo, O2-7-3-3 315 2018/06/19
  •  Recent studies on evaluation of auditory function for neonates Murakoshi M Proceedings of the Acoustical Society of Japan 2018 Spring Meeting, March 13-15, 2018, Saitama, 1-11-3 1479 2018/03/13
  •  Changes of dynamic characteristics in the neonatal external ear canal wall from birth to 6 months Kanka N,Murakoshi M,Hamanishi S,Wada H Proceedings of the 30th Bioengineering Conference of the JSME, December 14-15, 2017, Kyoto, 1B18 84 2017/12/14
  •  Development of CHO expression systems of recombinant inner-ear motor proteins having different affinity tags Murakoshi M,Wada H Proceedings of the 30th Bioengineering Conference of the JSME, December 14-15, 2017, Kyoto, 2B13 242 2017/12/14
  •  Hearing mechanism and its measurement and control Murakoshi M SICE Kyushu Forum 2017, November 24, 2017, Kagoshima 8 2017/11/24
  •  Restoration of localization pendrin mutants causing sensorineural hearing loss by salicylate derivatives Chaen T,Matsuzaki K,Murakoshi M Proceedings of the 28th JSME Conference on Frontiers in Bioengineering, October 27-29, 2017, Tokushima, 2A11 1 2017/10/28
  •  Establishment of CHO cells expressing Avi-tagged prestin and selection of high expressing lines by flow cytometry Matsuno K,Matsuzaki K,Murakoshi M Proceedings of the 28th JSME Conference on Frontiers in Bioengineering, October 27-29, 2017, Tokushima, 2A12 1 2017/10/28
  •  The role of the outer hair cells stacked in three rows and its molecular structure Murakoshi M J Acoust Soc Jpn 73 10 662 2017/10/01
  •  Construction of a mammalian cell line stably expressing the inner-ear motor protein prestin Murakoshi M,Wada H Proceedings of the 62nd Congress of Japan Audiological Society, October 18-20, 2017, Fukuoka, 19 278 2017/09/30
  •  Dynamic characteristic changing of the external ear canal wall with an increase in neonatal chronological age Kanka N,Murakoshi M,Hamanishi S,Wada H Proceedings of the 5th Switzerland-Japan Workshop on Biomechanics (SJB2017), September 14-17, 2017, Zermatt, Switzerland 32 2017/09/14
  •  Decipherment of the membrane structure of the inner ear motor protein prestin by force spectroscopy Murakoshi M,Wada H Proceedings of the 5th Switzerland-Japan Workshop on Biomechanics (SJB2017), September 14-17, 2017, Zermatt, Switzerland 11 2017/09/14
  •  Dynamic characteristics of neonatal ear up to 6 kHz using a finite element modeling approach Hamanishi S,Murakoshi M,Wada H Proceedings of the XXVI Congress of the International Society of Biomechanics (ISB2017) incorporating the 9th Asian-Pacific Conference on Biomechanics (AP Biomech 2017), July 23-27, 2017, Brisbane, Australia 611 2017/07/23
  •  Difference in the dynamic behavior of the hearing apparatus between neonates and adults: the effects on tympanometry Murakoshi M,Hamanishi S,Wada H Proceedings of the XXVI Congress of the International Society of Biomechanics (ISB2017) incorporating the 9th Asian-Pacific Conference on Biomechanics (AP Biomech 2017), July 23-27, 2017, Brisbane, Australia 610 2017/07/23
  •  Learn from the mechanics of hearing -From the inner ear tissue to the membrane protein- Murakoshi M Mol Electron & Bioelectron 28 4 2017/06/06
  •  Numerical analysis of the changes in the dynamic behavior of the organ of Corti caused by the cochlear outer hair cell injury due to traumatic stimuli Namikawa R,Matsuzaki K,Murakoshi M Proceedings of the 48th Bachelor Thesis Presentations by the Student Members of the Kyushu Branch of the JSME, March 3, 2017, Naha, 245 1 2017/03/03
  •  Construction of an expression system of the His-tagged prestin using Chinese hamster ovary cells Katsuda R,Murakoshi M,Matsuzaki K,Wada H Proceedings of the 29th Bioengineering Conference of the JSME, January 19-20, 2017, Nagoya, 2A35 1 2017/01/19
  •  Engineering consideration of hearing and its application Murakoshi M Proceedings of the 3rd Research Meeting 2016 of the Electronics Division, The Kinki Cheical Society Japan, January 16, 2017, Osaka 1 2017/01/16
  •  Mechanical understanding of biomembrane molecules and its application to nanobiodevice innovation Murakoshi M Proceedings of the 6th CSJ Chemistry Festa, November 14-16, 2016, Tokyo, B3-09 86 2016/11/14
  •  Restoration by salicylate derivatives of localization and function of a pendrin mutant Chaen T,Murakoshi M,Matsuzaki K,Wada H Proceedings of the 27th JSME Conference on Frontiers in Bioengineering, October 22-23, 2016, Sapporo, B104 9 2016/10/23
  •  Mechanism of hearing loss caused by the loss of outer hair cells –FEM analysis– Murakoshi M,Wada H Proceedings of the 61st Congress of Japan Audiological Society, October 19-21, 2016, Morioka, Iwate, 177 605 2016/10/19
  •  Dynamic characteristics of the outer and middle ears in neonates Wada H,Murakoshi M,Aithal V,Kei J,Hamanishi S,Driscoll C,Swanston A Proceedings of the XXXIII World Congress of Audiology, September 18-21, 2016, Vancouver, Canada - 2016/09/18
  •  Analysis of the middle-ear dynamics of neonates -Study by using the sweep frequency impedance (SFI) meter- Wada H,Matsutani S,Kobayashi T,Kiyokawa H,Kakuta R,Murakoshi M,Hamanishi S,Aithal V,Kei J Proceedings of the 11th ERA/OAE Research Meeting of the Japan Audiological Society, July 10, Tokyo, 7 12 2016/07/10
  •  Coordinating movement of outer hair cells and cochlear amplification Murakoshi M,Wada H Proceedings of the 11th ERA/OAE Research Meeting of the Japan Audiological Society, July 10, Tokyo 11 2016/07/10
  •  Analysis of neonatal tympanometry using SFI data Murakoshi M,Kanka N,Hamanishi S,Wada H Proceedings of the IUTAM Symposium on Advances in Biomechanics of Hearing, May 17-20, 2016, Stuttgart, Germany 44 2016/05/17
  •  Mechanical understanding of biomembrane molecules and its application to nanobiodevice innovation Murakoshi M Proceedings of the 96th Annual Meeting of the Chemical Society of Japan, March 24-27, 2016, Kyoto, 1S8-13 1 2016/03/24
  •  Effect of surface roughness on friction factor of gas flow in micro-tubes Tanaka G,Hong C,Asako Y,Katanoda H,Fukuhara M,Murakoshi M Proceedings of the 69th Annual Meeting of the Kyushu Branch of the JSME, March 15, 2016, Kumamoto, E-08 2016 69 187 2016/03/15
  •  Semi-local friction factors of gaseous flow through glass micro-tube Kawano T,Hong C,Asako Y,Katanoda H,Fukuhara M,Murakoshi M Proceedings of the 69th Annual Meeting of the Kyushu Branch of the JSME, March 15, 2016, Kumamoto, E-07 2016 69 185 2016/03/15
  •  Study on dynamic biped walking by expansion of legs Iiyama H,Matsuzaki K,Murakoshi M Proceedings of the 47th Bachelor Thesis Presentations by the Student Members of the Kyushu Branch of the JSME, March 4, 2016, Kagoshima, C44 - 2016/03/04
  •  Development of mammalian cell expressing pendrin mutants and its rescue Chaen T,Matsuzaki K,Murakoshi M Proceedings of the 47th Bachelor Thesis Presentations by the Student Members of the Kyushu Branch of the JSME, March 4, 2016, Kagoshima, C35 - 2016/03/04
  •  Construct of a cell line stably expressing Avi-tagged prestin Matsuno K,Matsuzaki K,Murakoshi M Proceedings of the 47th Bachelor Thesis Presentations by the Student Members of the Kyushu Branch of the JSME, March 4, 2016, Kagoshima, C34 - 2016/03/04
  •  Effects of maturation on dynamic behavior of ear canal wall and middle ear in neonates Hamanishi S,Murakoshi M,Steele C,Puria S,Wada H Proceedings of the 28th Bioengineering Conference of the JSME, January 9-10, 2016, Tokyo, 1F44 1 2016/01/09
  •  Development of a mammalian cell expression system of the motor protein prestin expressing in the inner ear Murakoshi M,Kai K,Wada H Proceedings of the 28th Bioengineering Conference of the JSME, January 9-10, 2016, Tokyo, 1C22 1 2016/01/09
  •  Development of a diagnostic apparatus using a probe tone of the sweeping sinusoidal frequency for hearing in neonates Keoroshi D,Matsuzaki K,Murakoshi M Proceedings of the 26th JSME Conference on Frontiers in Bioengineering, October 2-3, 2015, Fukuoka, C201 2015 26 131 2015/10/01
  •  Analysis of tympanogram in neonates Kanka N,Murakoshi M,Matsuzaki K,Wada H Proceedings of the 26th JSME Conference on Frontiers in Bioengineering, October 2-3, 2015, Fukuoka, A109 17 2015/10/01
  •  Construction of an expression vector of His-tagged prestin Katsuda R,Matsuzaki K,Murakoshi M Proceedings of the 26th JSME Conference on Frontiers in Bioengineering, October 2-3, 2015, Fukuoka, B110 2015 26 43 2015/10/01
  •  Construction of a stable expression system of the motor protein prestin labled with FLAG tag and its purification Kawahara A,Matsuzaki K,Murakoshi M Proceedings of the 26th JSME Conference on Frontiers in Bioengineering, October 2-3, 2015, Fukuoka, B112 2015 26 47 2015/10/01
  •  Construction of a mammalian vector for high expression of the motor protein prestin Kai K,Matsuzaki K,Murakoshi M Proceedings of the 26th JSME Conference on Frontiers in Bioengineering, October 2-3, 2015, Fukuoka, B111 2015 26 45 2015/10/01
  •  Sound amplification mechanism by three rows of outer hair cells in mammals Murakoshi M,Wada H Proceedings of the 8th Asian-Pacific Conference on Biomechanics (AP Biomech 2015), September 16-19, 2015, Sapporo, Japan 2015 8 141 2015/09/16
  •  Dynamic biped walking by expansion and contraction of legs Imamura S,Matsuzaki K,Murakoshi M Proceedings of the Dynamics and Design Conference 2015, August 25-28, Hirosaki, 160 2015 - 2015/08/25
  •  Maturation of the neonatal ear canal: sweep frequency impedance (SFI) and finite element model approaches Hamanishi S,Murakoshi M,Steele C,Wada H,Puria S Proceedings of the 7th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO 2015), July 1-5, 2015, Aalborg, Denmark 61 2015/07/01
  •  Changes in dynamic characteristics of the external ear canal wall during the first 3 months of life Murakoshi M,Hamanishi S,Wada H Proceedings of the 7th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO 2015), July 1-5, 2015, Aalborg, Denmark 39 2015/07/01
  •  Topology of prestin expressed in the CHO cell membrane -atomic force microscopy study- Murakoshi M,Wada H Proceedings of the 2015 Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C 2015), June 17-20, 2015, Snowbird, Utah, USA 283 2015/06/17
  •  Numerical analysis of the elaborate sound amplification mechanism of the mammalian inner ear Murakoshi M,Wada H Proceedings of the World Congress of Medical Physics and Biomedical Engineering 2015, June 7-12, 2015, Toronto, Canada 127 2015/06/06
  •  Analysis of the dynamic behavior of the auditory system in newborns focused on the external ear-canal deformation Murakoshi M,Wada H Proceedings of the 54th Annual Conference of the JSMBE, May 7-9, 2015, Nagoya 277 2015/05/07
  •  A hyprid ear canal and middle ear model approach for neonates Hamanishi S,Murakoshi M,Steele C,Wada H,Puria S Abstract of the 38th Annual MidWinter Meeting of the Association for Research in Otolaryngology, February 21-25, 2015, Baltimore, Maryland, USA 69 2015/02/21
  •  Analysis of dynamic behavior of neonatal ear canal and middle ear using a finite-element method Hamanishi S,Murakoshi M,Steele C,Puria S,Wada H Proceedings of the 27th Bioengineering Conference of the JSME, January 9-10, 2015, Niigata, 2E21 489 2015/01/09
  •  Analysis of middle ear diagnostic tympanometry in neonates Murakoshi M,Hamanishi S,Wada H Proceedings of the 27th Bioengineering Conference of the JSME, January 9-10, 2015, Niigata, 2E22 491 2015/01/09
  •  Construction of an expression system of the motor protein prestin labeled with affinity tags Kawahara A,Katsuda R,Murakoshi M Proceedings of the 25th JSME Conference on Frontiers in Bioengineering, October 3-4, 2014, Tottori, B109 2014 25 45 2014/10/02
  •  Development of a real-time simulator of the human auditory system for next-generation hearing aid system Murakoshi M Proceedings of the 2014 JSPE Autumn Meeting, September 16, 2014, Tottori 41 2014/09/16
  •  AFM imaging of the structure of the motor protein prestin purified and reconstituted into an artificial lipid bilayer Wada H,Kumano S,Murakoshi M,Iida K,Hamana H Proceedings of the 4th Japan-Switzerland Workshop on Biomechanics, September 1-4, 2014, Shima, Mie, Japan 128 2014/09/01
  •  Force spectroscopy study on transmembrane structure of the motor protein prestin expressed in the inner ear Murakoshi M,Kawase T,Wada H Proceedings of the 4th Japan-Switzerland Workshop on Biomechanics, September 1-4, 2014, Shima, Mie, Japan 82 2014/09/01
  •  Chronological changes in dynamic behavior of the hearing system in newborns Murakoshi M,Kakuta R,Matsutani S,Kobayashi T,Wada H Proceedings of the 26th Bioengineering Conference of the JSME, January 11-12, 2014, Sendai, 2D12 391 2014/01/11
  •  Dynamic behavior of the external and middle ears in neonates Murakoshi M,Wada H Proceedings of the Kagoshima Meeting of the Kyusyu Branch of the JSME, September 27-28, 2014, Kagoshima, 1H3 2013 237 2013/09/28
  •  Dynamic behavior of the organ of Corti in the basal and apical regions of the guinea pig cochlea: theoretical considerations Kitamura T,Murakoshi M,Wada H Proceedings of the 6th East Asian Pacific Student Workshop on Nano-Biomedical Engineering, March 23-34, 2013, Singapore 50 2013/03/23
  •  Evaluation of electrophysiological properties of the motor protein prestin expressed in the inner ear Ogawa Y,Murakoshi M,Wada H Proceedings of the 6th East Asian Pacific Student Workshop on Nano-Biomedical Engineering, March 23-34, 2013, Singapore 82 2013/03/23
  •  Auditory system in knock-in mouse models of Pendred sydrome Koyama S,Ikehara Y,Murakoshi M,Hashimoto S,Nishio S,Takumi Y,Usami S,Wada H Abstract of the 36th Annual MidWinter Meeting of the Association for Research in Otolaryngology, February 16-20, 2013, Baltimore, Maryland, USA 1063 2013/02/16
  •  Protective mechanism of the outer hair cells from traumatic noise by prior whole-body heat stress Murakoshi M,Kitsunai Y,Yoshida N,Iida K,Kumano S,Kobayashi T,Wada H Abstract of the 36th Annual MidWinter Meeting of the Association for Research in Otolaryngology, February 16-20, 2013, Baltimore, Maryland, USA 45 2013/02/16
  •  Restoration by salicylate of transport function and anion exchanger activity of missense pendrin mutations Wada H,Ishihara K,Okuyama S,Kumano S,Iida K,Hamana H,Murakoshi M,Kobayashi T,Usami S,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N Abstract of the 36th Annual MidWinter Meeting of the Association for Research in Otolaryngology, February 16-20, 2013, Baltimore, Maryland, USA 1118 2013/02/16
  •  Analysis by using the sweep frequency impedance (SFI) meter of dynamic behavior of hearing system in newborns Murakoshi M,Yoshida N,Ogawa Y,Kiyokawa H,Kakuta R,Yamada M,Takahashi R,Tanigawara S,Matsutani S,Kobayashi T,Wada H Proceedings of the 25th Bioengineering Conference of the JSME, January 9-11, 2013, Tsukuba, 2B02 275 2013/01/09
  •  Search for drugs to promote restoration of a pendrin mutant causing hereditary hearing loss Koyama S,Sato H,Murakoshi M,Kobayashi T,Usami S,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N,Ishihara K,Wada H Proceedings of the 25th Bioengineering Conference of the JSME, January 9-11, 2013, Tsukuba, 3D12 573 2013/01/09
  •  Development of a planar patch clamp system for measuring electrophysiological properties of a membrane protein prestin expressed in the inner ear Ogawa Y,Murakoshi M,Wada H Proceedings of the 25th Bioengineering Conference of the JSME, January 9-11, 2013, Tsukuba, 3D11 571 2013/01/09
  •  Conditioning-related protection of sensory cells from acoustic injury Murakoshi M,Kitsunai Y,Suzuki T,Yoshida N,Kobayashi T,Wada H Proceedings of the Biofrontier Symposium 2012 of the JSME, October 5, 2012, Hirosaki 5p 2012/10/05
  •  Analysis of dynamic behavior of the external ear canal in neonates —theoretical considerations— Takeda S,Murakoshi M,Biwa T,Wada H Proceedings of the 23rd JSME Conference on Frontiers in Bioengineering, October 5-6, 2012, Hirosaki 59 2012/10/05
  •  Restoration by salicylate derivatives of localization of a pendrin mutant causing hereditary hearing loss Sato H,Koyama S,Murakoshi M,Wada H Proceedings of the 23rd JSME Conference on Frontiers in Bioengineering, October 5-6, 2012, Hirosaki 2012 23 53 2012/10/05
  •  Effects of salicylate derivatives on changes in localization of H723R pendrin mutant expressed in cultured cells Koyama S,Sato H,Murakoshi M,Kobayashi T,Usami S,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N,Ishihara K,Wada H Proceedings of the Inner Ear Biology 2012, September 29-October 2, 2012, Tubingen, Germany 116 2012/09/29
  •  Restoration of transport function and anion exchanger activity of missense pendrin mutations by salicylate Wada H,Ishihara K,Okuyama S,Kumano S,Iida K,Hamana H,Murakoshi M,Kobayashi T,Usami S,Ikeda K,Haga Y,Tsumoto K,Nakamura H,Hirasawa N Proceedings of the Inner Ear Biology 2012, September 29-October 2, 2012, Tubingen, Germany 54 2012/09/29
  •  Development of a ultrasonic driven self-contained micropump system Chikada Y,Suda S,Matsunaga T,Koyama S,Murakoshi M,Wada H,Haga Y Proceedings of the Japan Biomedical Engineering Symposium (JBMES) 2012 of the JSMBE, September 7-8, 2012, Osaka 82 2012/09/07
  •  Sweep frequency impedance (SFI) measurements for evaluation of middle ear function in neonates Aithal V,Aithal S,Kei J,Driscoll C,Swanston A,Roberts K,Wada H,Murakoshi M Proceedings of the 20th ASA Conference, July 1-4, 2012, Adelaide, Australia - 2012/07/01
  •  Dynamic behavior of the neonatal ear canal: theoretical considerations Murakoshi M,Takeda S,Wada H Proceedings of the 6th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2012), June 27-July 1, 2012, Daegu, Korea 58 2012/06/27
  •  Assessment of the dynamic characteristics of the middle ear in neonates using the sweep frequency impedance (SFI) meter Wada H,Yoshida N,Kiyokawa H,Murakoshi M,Matsutani S,Kobayashi T Proceedings of the 6th International Symposium on Middle-Ear Mechanics in Research and Otology (MEMRO2012), June 27-July 1, 2012, Daegu, Korea 41 2012/06/27
  •  Analysis of ear-canal dynamics in neonates: theoretical considerations Murakoshi M,Takeda S,Wada H Proceedings of the NHS2012, June 5-7, 2012, Cernobbio, Italy 136 2012/06/05
  •  Dynamic characteristics of the middle ear in newborns –study using the sweep frequency impedance (SFI) meter– Wada H,Yoshida N,Kiyokawa H,Murakoshi M,Matsutani S,Kobayashi T Proceedings of the NHS2012, June 5-7, 2012, Cernobbio, Italy 137 2012/06/05
  •  Prestin, the inner ear motor protein-its structure and function Wada H,Kumano S,Murakoshi M,Koyama S Proceedings of the 18th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre, March 5-6, 2012, Sendai, Japan - 2012/03/05
  •  Analysis of the dynamic characteristics of the middle ear in neonates Yoshida N,Kiyokawa H,Murakoshi M,Hamanishi S,Matsutani S,Kei J,Kobayashi T,Wada H Proceedings of the 24th Bioengineering Conference of the JSME, January 7-8, 2012, Osaka, 7E45, CD-ROM 2p 2012/01/07
  •  Effects of salicylate on the auditory system in a knock-in mouse model for H723R mutation in Pendrin Ikehara Y,Koyama S,Murakoshi M,Ikeda R,Nakaya K,Hashimoto S,Nishio S,Takumi Y,Oshima T,Usami S,Kobayashi T,Wada H Proceedings of the 24th Bioengineering Conference of the JSME, January 7-8, 2012, Osaka, 8H12, CD-ROM 2p 2012/01/07
  •  Development of a sweep frequency impedance (SFI) meter for diagnosis of middle ear function in neonates Yoshida N,Kiyokawa H,Murakoshi M,Hamanishi S,Matsutani S,Kei J,Kobayashi T,Wada H Proceedings of the 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering, December 12-14, 2011, Singapore 136 2011/12/12
  •  Effects of salicylate on sensorineural hearing loss in Pendred syndrome Ikehara Y,Koyama S,Murakoshi M,Ikeda R,Nakaya K,Hashimoto S,Nishio S,Takumi Y,Oshima T,Usami S,Kobayashi T,Wada H Proceedings of the 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering, December 12-14, 2011, Singapore 134 2011/12/12
  •  Transport of pendrin mutant causing sensorineural hearing loss to plasma membrane by salicylate derivatives Sakai N,Koyama S,Murakoshi M,Hirasawa N,Nakamura H,Ishihara K,Wada H Proceedings of the 22nd JSME Conference on Frontiers in Bioengineering, October 7-8, 2011, Tsu, B217 2011 22 111 2011/10/07
  •  Analysis of middle-ear dynamic characteristics in neonates using a sweep frequency impedance (SFI) meter Yoshida N,Kiyokawa H,Murakoshi M,Hamanishi S,Matsutani S,Kei J,Kobayashi T,Wada H Proceedings of the 22nd JSME Conference on Frontiers in Bioengineering, October 7-8, 2011, Tsu, B201 127 2011/10/07
  •  Effects of salicylate on the auditory system in C57BL/6 mice Ikehara Y,Koyama S,Murakoshi M,Usami S,Kobayashi T,Hashimoto S,Nishio S,Takumi Y,Ikeda R,Nakaya K,Oshima T,Wada H Proceedings of the 22nd JSME Conference on Frontiers in Bioengineering, October 7-8, 2011, Tsu, B205 135 2011/10/07
  •  Atomic force microscopic analysis of membrane topology of the inner ear motor protein prestin Murakoshi M,Wada H Proceedings of the 50th Annual Conference of the JSMBE, April 29-May 2, 2011, Tokyo 207 2011/04/29
  •  Restoration by salicylate of transport function and anion exchanger activity of pendrin mutants Wada H,Ishihara K,Koyama S,Murakoshi M,Kumano S,Hamana H Proceedings of the 16th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre, March 22-23, 2011, Sendai, Japan - 2011/03/22
  •  Measurement of nanomechanical motion of the cell expressing the motor protein prestin using an atomic force microscope Nomura Y,Murakoshi M,Wada H Proceedings of the 41st Bachelor Thesis Presentations by the Student Members of the Tohoku Branch of the JSME, March 3, 2011, Morioka, 305 56 2011/03/03
  •  Importance of outer hair cell coordinating movement for cochlear amplification Suzuki S,Murakoshi M,Wada H Proceedings of the 23rd Bioengineering Conference of the JSME, January 8-9, 2011, Kumamoto 497 2011/01/08
  •  ELF magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells Koyama S,Murakoshi M,Sakurai T,Miyakoshi J,Wada H Proceedings of the 23rd Bioengineering Conference of the JSME, January 8-9, 2011, Kumamoto 489 2011/01/08
  •  Analysis of transmembrane structure of the inner ear motor protein prestin-atomic force microscopy study- Murakoshi M,Kawase T,Wada H Proceedings of the 23rd Bioengineering Conference of the JSME, January 8-9, 2011, Kumamoto, No. 9J-08. 283 2011/01/08
  •  Analysis of transmembrane structure of prestin by single molecule force spectroscopy Murakoshi M,Kawase T,Kumano S,Wada H Proceedings of the 47th Inner Ear Biology Workshop, August 29-September 1, 2010, Prague, Czech Republic 44 2010/08/29
  •  8H-18 Importance of outer hair cell coordinating movement for cochlear amplification SUZUKI Sho,MURAKOSHI Michio,WADA Hiroshi 2010 23 283 2011/01/07
  •  Translocation of prestin having mutation in the GTSRH sequence by salicylate Wada H,Kumano S,Murakoshi M,Iida K,Ishihara K,Tsumoto K,Ikeda K,Kobayashi T Proceedings of the 47th Inner Ear Biology Workshop, August 29-September 1, 2010, Prague, Czech Republic 46 2010/08/29
  •  Single molecule force spectroscopy of the inner-ear motor protein prestin using an atomic force microscope Murakoshi M,Kawase T,Kumano S,Wada H Proceedings of the 6th World Congress on Biomechanics, August 1-6, 2010, Singapore - 2010/08/01
  •  Analysis by single molecule force spectroscopy of the transmembrane structure of prestin Kawase T,Kumano S,Murakoshi M,Hamana H,Wada H Proceedings of the 45th Annual Meeting of the Tohoku Branch of the JSME, March 12, 2010, Sendai 182 2010/03/12
  •  191 Single Molecule Force Spectroscopic Analysis of Prestin Membrane Topology KAWASE Tomohiro,KUMANO Shun,MURAKOSHI Michio,HAMANA Hiroshi,Wada Hiroshi 2010 45 182 2010/03/12
  •  High resolution imaging by atomic force microscopy of prestin purified and reconstituted into an artificial lipid bilayer Kumano S,Murakoshi M,Hamana H,Wada H Abstract of the 33rd Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 6-10, 2010, Anaheim, CA, USA 580 2010/02/06
  •  Immune atomic force microscopy of the inner ear motor prestin using Qdots Murakoshi M,Hamana H,Kumano S,Wada H Proceedings of the SMART-Tohoku GCOE joint Workshop on Micro & Nano Bioengineering: MIT, NUS, NTU and Tohoku, January 11-12, 2010, Singapore 47 2010/01/11
  •  Comparative analysis of the dynamic characteristics of the middle ear between neonates and adults using a sweep frequency impedance meter Seshimo N,Hamanishi S,Murakoshi M,Mazlan R,Kei J,Wada H Proceedings of the 22nd Bioengineering Conference of the JSME, January 9-10, 2010, Okayama 2009 22 125 2010/01/09
  •  Importance of the three rows of outer hair cells for cochlear amplification Suzuki S,Murakoshi M,Wada H Proceedings of the 22nd Bioengineering Conference of the JSME, January 9-10, 2010, Okayama 96 2010/01/09
  •  Structural analysis by atomic force microscopy of the motor protein prestin reconstituted into an artificial lipid bilayer Kumano S,Murakoshi M,Hamana H,Wada H Proceedings of the 22nd Bioengineering Conference of the JSME, January 9-10, 2010, Okayama 2009 22 95 2010/01/09
  •  440 Effects of Heat Stress on Filamentous Actin and Prestm in Mouse Outer Hair Cells KITSUNAI Yoko,MURAKOSHI Michio,YOSHIDA Naohiro,KOBAYASHI Toshimitsu,WADA Hiroshi 2006 19 380 2007/01/06
  •  Atomic force microscopic imaging of the inner ear motor protein prestin using quantum dots Murakoshi M,Hamana H,Kumano S,Wada H Proceedings of the Watching Biomolecules in Action Symposium & 2nd Kanazawa Bio-AFM Workshop, December 14-17, 2009, Osaka, Japan 42 2009/12/14
  •  201 Enhancement of the Activity of the Motor Protein Prestin by Mutations KUMANO Shun,IIDA Koji,MURAKOSHI Michio,TSUMOTO Kouhei,IKEDA Katsuhisa,KUMAGAI Izumi,KOBAYASHI Toshimitsu,WADA Hiroshi 2006 19 12 2007/01/06
  •  Visualization by atomic force microscopy of the inner ear motor protein prestin using Qdot Murakoshi M,Hamana H,Kumano S,Wada H Proceedings of the 43rd Annual Meeting of the Tohoku Branch of the JSMBE, November 21, 2009, Fukushima, B2-1 25 2009/11/21
  •  202 Interaction Between the Motor Protein Prestin and Chloride IIDA Koji,TSUMOTO Kouhei,MURAKOSHI Michio,KUMANO Shun,IKEDA Katsuhisa,KOBAYASHI Toshimitsu,KUMAGAI Izumi,WADA Hiroshi 2006 19 14 2007/01/06
  •  Understanding of the mammalian auditory system at the molecular level(哺乳類の聴覚システムの分子レベルでの理解) Wada H,Murakoshi M,Iida K,Kumano S The 11th International Symposium on Future Medical Engineering Based on Bio-nanotechnology, July 25, 2009, Tokyo, Japan - 2009/07/25
  •  Effects of mutations in unique amino acids of prestin on its characteristics Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the 8th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre, December 5-6, 2008, Singapore - 2008/12/05
  •  Site-directed mutagenesis of unique amino acids in the motor protein prestin Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the JSME Annual Meeting 2008, August 3-7, 2008, Kanagawa 2008 269 2008/08/03
  •  Contribution of the GTSRH sequence to the folding of prestin: refolding of transport-defective prestin mutants by salicylate Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Abstract of the 31st Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 16-21, 2008, Phoenix, Arizona, USA 137 2008/02/16
  •  Heterologous expression of the outer hair cell motor protein prestin in SF9 cells Tadenuma T,Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Abstract of the 31st Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 16-21, 2008, Phoenix, Arizona, USA 670 2008/02/16
  •  Immune atomic force microscopy of the plasma membrane of prestin-transfected Chinese hamster ovary cells using quantum dots Murakoshi M,Iida K,Kumano S,Wada H Abstract of the 31st Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 16-21, 2008, Phoenix, Arizona, USA 671 2008/02/16
  •  Expression of functional prestin, the outer hair cell motor protein, using the baculovirus expression Tadenuma T,Iida K,Murakoshi M,Kumano S,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the 20th Bioengineering Conference of the JSME, January 25-26, 2008, Tokyo 85 2008/01/25
  •  Imaging by atomic force microscopy of the motor protein prestin labeled with quantum dots Murakoshi M,Iida K,Kumano S,Wada H Proceedings of the 20th Bioengineering Conference of the JSME, January 25-26, 2008, Tokyo 83 2008/01/25
  •  Correction of the activity of prestin mutants by addition of salicylate Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the 20th Bioengineering Conference of the JSME, January 25-26, 2008, Tokyo 87 2008/01/25
  •  Enthalpy measurement of anion binding to the motor protein prestin by isothermal titration calorimetry Iida K,Tsumoto K,Murakoshi M,Kumano S,Ikeda K,Kobayashi T,Kumagai I,Wada H Proceedings of the 3rd Tohoku-NUS Joint Symposium on Nano-Biomedical Engineering in the East Asian-Pacific Rim Region, December 10-11, 2007, Singapore 111 2007/12/10
  •  Interaction of the inner ear motor protein prestin with chloride studied by isothermal titration calorimetry Iida K,Tsumoto K,Murakoshi M,Kumano S,Ikeda K,Kobayashi T,Kumagai I,Wada H Proceedings of the 3rd Asian Pacific Conference on Biomechanics, November 5-11, 2007, Tokyo, Japan (J Biomech Sci Eng 2, Suppl.1) 2007 3 S137 2007/11/05
  •  Misfolding and mislocalization by mutations of the motor protein prestin Kumano S,Iida K,Murakoshi M,Tsumoto K,Kumagai I,Kobayashi T,Wada H Proceedings of the 3rd Asian Pacific Conference on Biomechanics, November 5-11, 2007, Tokyo, Japan (J Biomech Sci Eng 2, Suppl.1) 2007 3 S136 2007/11/05
  •  Heat-stress actuated mechanism of the inner ear protecting it from traumatic noise exposure Murakoshi M,Kitsunai Y,Yoshida N,Iida K,Kumano S,Kobayashi T,Wada H Proceedings of the 3rd Asian Pacific Conference on Biomechanics, November 5-11, 2007, Tokyo, Japan (J Biomech Sci Eng 2, Suppl.1) 2007 3 S135 2007/11/05
  •  Heat-stress actuated protective mechanism of the inner ear against noise-induced hearing loss Murakoshi M,Kitsunai Y,Yoshida N,Iida K,Kumano S,Kobayashi T,Wada H Proceedings of the 19th International Congress on Acoustics, September 2-7, 2007, Madrid, Spain BIO-02-002 2007/09/02
  •  Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H IEICE technical report, 2007 107 187 19 2007/08/10
  •  Improper membrane-targeting of prestin by mutations in the GTSRH sequence Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the 6th Molecular Biology of Hearing & Deafness Conference, July 12-14, 2007, Hinxton, UK - 2007/07/12
  •  Prevention of noise-induced hearing loss by cochlear mechanism actuated by heat stress Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Proceedings of the Japan-China Conference on Acoustics, June 4-6, 2007, Sendai, Japan P-2-38 2007/06/04
  •  Heat stress-induced protection of outer hair cells from traumatic noise exposure Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Proceedings of the 19th Bioengineering Conference of the JSME, January 7-8, 2007, Sendai 44 2007/01/07
  •  Employment of cochlear mechanism actuated by stress to prevent noise-induced hearing loss Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Proceedings of the 9th International Symposium on Future Medical Engineering based on Bio-nanotechnology jointly organized with the 19th Bioengineering Conference, 2006 Annual Meeting of BED/JSME, January 7-9, 2007, Sendai, Japan 84 2007/01/07
  •  441 Changes in Filamentous Actin in Mouse Outer Hair Cells Following Repeated Heat Stress MURATANI Asako,KITSUNAI Yoko,MURAKOSHI Michio,YOSHIDA Naohiro,KOBAYASHI Toshimitsu,WADA Hiroshi 2006 19 382 2007/01/06
  •  Highly conserved GTSRH sequence required for the voltage-dependent charge transfer of the motor protein prestin Kumano S,Iida K,Murakoshi M,Tsumoto K,Ikeda K,Kumagai I,Kobayashi T,Wada H Proceedings of the 2nd Shanghai International Conference on Physiological Biophysics-Audition and Vision, November 3-7, 2006, Shanghai, China 241 2006/11/03
  •  Purification of the motor protein prestin and its interaction with chloride studied by isothermal titration calorimetry Iida K,Tsumoto K,Murakoshi M,Kumano S,Ikeda K,Kobayashi T,Kumagai I,Wada H Proceedings of the 2nd Shanghai International Conference on Physiological Biophysics-Audition and Vision, November 3-7, 2006, Shanghai, China 240 2006/11/03
  •  Imaging by atomic force microscopy of the motor protein prestin using prestin-transfected CHO cells Wada H,Murakoshi M,Gomi T,Iida K,Kumano S,Tsumoto K,Kumagai I,Ikeda K,Kobayashi T Proceedings of the 2nd Shanghai International Conference on Physiological Biophysics-Audition and Vision, November 3-7, 2006, Shanghai, China 242 2006/11/03
  •  Heat stress-induced changes in Young's modulus of outer hair cells in mice Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Suzuki T,Kobayashi T,Wada H Proceedings of the 2nd Shanghai International Conference on Physiological Biophysics-Audition and Vision, November 3-7, 2006, Shanghai, China 83 2006/11/03
  •  Topological characterization by atomic force microscopy of prestin Wada H,Murakoshi M,Gomi T Proceedings of the 5th World Congress of Biomechanics, July 29th-August 4th, 2006, Munich, Germany (J Biomech 39, Suppl.1) S228 2006/07/29
  •  Heat stress-induced cochlear protection from acoustic injury Murakoshi M,Yoshida N,Kitsunai Y,Iida K,Kumano S,Kobayashi T,Wada H Proceedings of the 9th Western Pacific Acoustics Conference, June 26-28, 2006, Seoul, Korea 168 2006/06/26
  •  Atomic force microscopic observation of the conformational changes in the voltage-dependent motor protein prestin Murakoshi M,He DZZ,Iida K,Kumano S,Wada H Proceedings of the 18th Bioengineering Conference of the JSME, January 13-14, 2006, Niigata 25 2006/01/13
  •  107 Purification and Characterization of the Motor Protein Prestin of Cochlear Outer Hair Cells IIDA Koji,KUMANO Shun,MURAKOSHI Michio,TSUMOTO Kouhei,IKEDA Katsuhisa,KUMAGAI Izumi,KOBAYASHI Toshimitsu,WADA Hiroshi 2005 18 21 2006/01/12
  •  Protection of outer hair cells from traumatic noise by prior whole-body heat stress Murakoshi M,Kitsunai Y,Yoshida N,Kobayashi T,Wada H Proceedings of the 2nd Asian Pacific Conference on Biomechanics, November 23-25, 2005, Taipei, Taiwan 14 2005/11/23
  •  Atomic force microscopic analysis of prestin-transfected CHO cell plasma membranes Murakoshi M,Gomi T,Iida K,Kumano S,Wada H Proceedings of the 6th International Symposium on Future Medical Engineering Based on Bio-nanotechnology, November 21, 2005, Sendai, Japan 56 2005/11/21
  •  108 Site-Directed Mutagenesis of the Conserved GTSRH Sequence in the Motor Protein Prestin KUMANO Shun,IIDA Koji,MURAKOSHI Michio,TSUMOTO Kouhei,IKEDA Katsuhisa,KUMAGAI Izumi,KOBAYASHI Toshimitsu,WADA Hiroshi 2005 18 23 2006/01/12
  •  Changes in structure and mechanical properties of mouse outer hair cells in response to whole-body heat stress Murakoshi M,Kitsunai Y,Yoshida N,Kobayashi T,Wada H Proceedings of the Second Japan-Switzerland Workshop on Biomechanics, September 12-16, 2005, Kyoto, Japan 100 2005/09/12
  •  Mechanical property change in outer hair cells caused by whole-body heat stress in mice Murakoshi M,Yoshida N,Kobayashi T,Wada H Proceedings of the 28th Annual Meeting of the Japanese Society of Biorheology, July 7-8, 2005, Sendai 54 2005/07/07
  •  Imaging of the cytoplasmic face of the prestin-expressing CHO cell membrane by atomic force microscopy Murakoshi M,Gomi T,Wada H Abstract of the 28th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology, February 19-24, 2005, New Orleans, Louisiana, USA 614 2005/02/19
  •  Observation of the plasma membrane of the CHO cells expressing the motor protein prestin by atomic force microscopy Murakoshi M,Wada H Proceedings of the 17th Bioengineering Conference of the JSME, January 22-23, 2005, Nagoya 2004 27 2005/01/22
  •  Effects of heat stress on the mechanical properties of outer hair cells in mice Murakoshi M,Yoshida N,Kobayashi T,Wada H Proceedings of the 15th JSME Conference on Frontiers in Bioengineering, November 6-7, 2004, Ube 7 2004/11/06
  •  Intraoperative measurement of ossicular mobility Murakoshi M,Koike T,Yuasa Y,Yuasa R,Kobayashi T,Wada H Proceedings of the 17th International Congress of Audiology, September 26-30, 2004, Phoenix, Arizona, USA 31 2004/09/26
  •  Development of an apparatus for diagnosis of ossicular chain mobility in humans Murakoshi M,Koike T,Yuasa Y,Yuasa R,Kobayashi T,Wada H Proceedings of the 14th JSME Conference on Frontiers in Bioengineering, September 18-19, 2003, Zao 2003 14 147 2003/09/18

Arts and Fieldwork

Patent

Theme to the desired joint research

○Analysis of the structure and function of the motor protein prestin
○Rescue of pendrin mutants causing hereditary hearing loss
○Development of a diagnostic system for newborn hearing screening

Grant-in-Aid for Scientific Research

○「鋭敏な哺乳類聴覚を実現するメゾスケールでの内耳分子機構とその応用に関する研究」(2023-2026) 
○「耳に入れた広帯域ノイズ音による頭蓋内圧の非侵襲計測技術の開発」(2021-2023) 
○「内耳増幅の超分子メカニズム解明を目指した膜タンパク質操作・計測技術と新機能の創生」(2017-2020) 

Competitive research funding,Contribution

○Development of a non-invasive diagnostic device for conductive hearing loss Medical Device Research Results Deployment Project Japan Agency for Medical Research and Development (AMED)(2023-2026)
○Mechanical understanding of biomembrane molecules and its application to nanobiodevice innovation PRESTO (Molecular technology and creation of new functions)  The Japan Science and Technology Agency (JST)(2013-2016)

Collaborative research,Consignment study

Classes (Bachelors)

○Mechanical Vibrations I and Exercise(BH)(2021)
○Frontier Project B(2020)
○Frontier Project A(2020)

Classes (Graduate Schools)

○Advanced Biomechanical Engineering A(2021)
○Advanced Biomechanical Engineering B(2021)

International Project

International Students

Lecture themes

○Mechanics of Hearing (MoH)
○Newborn Hearing Screening (NHS)

Others (Social Activities)

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