MIZUKOSHI Eishiro - Directory of Researchers at Kanazawa University

Faculty, Affiliation

University Hospital

College and School Educational Field

Graduate School of Advanced Preventive Medical Sciences
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

　TEL:076-265-2235　FAX:076-234-4250

Academic Background

【Academic background(Bachelor's Degree)】
Kanazawa University　199203

Career

Kanazawa University(2002/04/01-)
National Institutes of Health　Liver Diseases Section,NIDDK(1999/05/01-2001/08/31)

Year & Month of Birth

1967/11

Academic Society

Award

○Hamanako symposium research award(2004)
○Liver Forum in Kyoto research award(2007)
○Liver Forum in Kyoto research award(2007)
○Liver Forum in Kyoto research award(2007)
○Liver Forum in Kyoto research award(2007)
○Liver Forum in Kyoto research award(2007)

Specialities

Gastroenterology

Speciality Keywords

cancer, tumor immunology, hepatitis

Research Themes

cancer immunotherapy disease and host immune response steatohepatitis

Books

Papers

　Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.　HEPATOLOGY　53　4　1216　2011/04
　Prolonged recurrence-free survival following OK432-stimulated dendritic cell transfer into hepatocellular carcinoma during transarterial embolization.　2010/11
　A liver-derived secretory protein, selenoprotein P, causes insulin resistance.　2010/11
　Differential gene expression profiling in blood from patients with digestive system cancers.　2010/09
　Enhancement of tumor-specific T-cell responses by transcatheter arterial embolization with dendritic cell infusion for hepatocellular carcinoma. 　Int J Cancer　126　9　2164　2010/05

show all

　Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients.　Honda M, Fujinaga H, Tatsumi I, Mizukoshi E, Nakamoto Y, Kaneko S　68(24)　10267-79　2008/12
　Hepatitis C virus (HCV)-specific immune responses of long-term injection drug users frequently exposed to HCV.　Eisenbach C, Edlin BR, Newton KP, Raghuraman S, Weiler-Normann C, Tobler LH, Busch MP, Carrington M, McKeating JA, O'Brien TR, Rehermann B　198　 203-12　2008/07
　Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma. 　Mizukoshi E, Honda M, Arai K, Yamashita T, Nakamoto Y, Kaneko S.　JOURNAL OF HEPATOLOGY　49　6　946　2008/06
　Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus.　Mizukoshi E, Takamura T, Sakurai M, Takata Y, Arai K, Yamashita T, Nakamoto Y, Kaneko S　56　 1682-8　2007/12
　Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis.　Mizukoshi E, Kita Y, Sakurai M, Takata Y, Arai K, Yamashita T, Ohta T, Shimizu K, Nakamoto Y, Honda M, Takamura T, Kaneko S　102　 1939-46　2007/09
　Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study. 　Arai K, Sakai A, Mizukoshi E, Sakai Y, Kagaya T, Nakamoto Y, Honda M, Wada T, Yokoyama H and Kaneko S　2006/11
　Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma. 　, Nakamoto Y, Marukawa Y, Arai K, Yamashita T, Tsuji H,Kuzushima K, Takiguchi M and Kaneko S　43　 1284-1294　2006/06
　Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood. 　Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA and Rehermann B　107　 4424-4432　2006/06
　Identification of alpha-fetoprotein-derived peptides recognized by cytotoxic T lymphocytes in HLA-A24+ patients with hepatocellular carcinoma. 　, Nakamoto Y, Tsuji H, Yamashita T and Kaneko S　118　 1194-1204　2006/03
　Effects of antiviral therapy on the cellular immune response in acute hepatitis C.　HEPATOLOGY　40　1　87-97　2004/07
　Kinetics of CD4+ and CD8+ memory T-cell responses during hepatitis C virus rechallenge of previously recovered chimpanzees.　JOURNAL OF VIROLOGY　77　8　4781-4793　2003/04
　Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune responses and vaccine studies　JOURNAL OF VIROLOGY　76　12　6093-6103　2002/06
　Cross-reactivity between hepatitis C virus and Influenza A virus determinant-specific cytotoxic T cells　JOURNAL OF VIROLOGY　75　23　11392-11400　2001/12
　Serum levels of soluble interferon Alfa/Beta receptor as an inhibitory factor of interferon in the patients with chronic hepatitis C　HEPATOLOGY　30　5　1325-1331　1999/11
　Upregulation of Type I interferon receptor by IFN-gamma　Journal of Interferon and Cytokine Research　19　9　1019-1023　1999/09
　Expression of interferon alpha/beta receptor in the liver of chronic hepatitis C patients　Journal of Medical Virology　56　3　217-223　1998/11

Conference Presentations

Others

　Immune responses and immunity in hepatitis C virus infection.　36　12　799-808　2001/12
　Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma.　Honda M, Arai K, Yamashita T, Nakamoto Y, Kaneko S　49　946-54　2008
　Combined therapy of transcatheter hepatic arterial embolization with intratumoral dendritic cell infusion for hepatocellular carcinoma: clinical safety.　Mizukoshi E, Tsuji H, Sakai Y, Kitahara M, Arai K, Yamashita T, Yokoyama K, Mukaida N, Matsushima K, Matsui O, Kaneko S　147　 296-305　2007

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「肝細胞癌に対する細胞性免疫治療に関する基礎的研究」(2003-)　
○「癌特異抗原を用いた肝癌の細胞性免疫療法に関する基礎的検討」(2005-)　
○「肝細胞癌治療後の再発制御を目的とした癌免疫療法の開発」(2007-)　
○「ペプチドワクチンを用いた肝細胞癌免疫療法の開発」(2010-2011)　
○「細胞傷害性T細胞レセプターを用いた肝細胞癌免疫治療に関する基礎的検討」(2013-2015)　
○「Immunomeのシングルセル解析に基づいた肝癌新規分類法の確立」(2016-)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

○Disease Control and Homeotasis(2017)
○Environment and Health -Introductory(2017)
○Disease Control and Homeotasis(2016)
○Environment and Health -Introductory(2016)

Professor　MIZUKOSHI Eishiro

Faculty, Affiliation

College and School Educational Field

Laboratory

Academic Background

Career

Year & Month of Birth

Academic Society

Award

Specialities

Speciality Keywords

Research Themes

cancer immunotherapy disease and host immune response steatohepatitis

Books

Papers

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

Professor MIZUKOSHI Eishiro

Faculty, Affiliation

College and School Educational Field

Laboratory

Academic Background

Career

Year & Month of Birth

Academic Society

Award

Specialities

Speciality Keywords

Research Themes

cancer immunotherapy disease and host immune response steatohepatitis

Books

Papers

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

Professor　MIZUKOSHI Eishiro