last modified：2025/04/08
Associate Professor KONNO, Hiroki
Faculty, Affiliation
WPI Nano Life Science Institute
College and School Educational Field
Division of Natural Sciences, Graduate School of Natural Science and Technology
Division of Natural System, Graduate School of Natural Science and Technology
Course in Biosystems, School of Biological Science and Technology, College of Science and Engineering
Laboratory
Academic Background
Career
Kanazawa University(2018/04-)
Kanazawa University(2011/11-2018/03)
Kitasato University(2010/04-2011/10)
Tokyo Institute of Technology(2009/08-2011/10)
Tokyo Institute of Technology(2005/08-2009/07)
JST/ERATO(2002/04-2005/07)
JSPS Research Fellowship for Young Dcientists (2000/01-2002/03)
Iwate Prefectural Kamaishi Hospital(1994/04-1995/03)
Year & Month of Birth
1971/02
Academic Society
Award
Specialities
Speciality Keywords
Research Themes
Books
- Hiroki Konno Time lapseimaging of amiroid fibril growth of yeast prion 2020/11/10
Papers
- Structure of the C-terminal domain of the epsilon subunit of chloroplast-type F1 Y agi H Konno,H. Murakami-Fuse T,Akutsu H,Hisabori T Biochim Biophys Acta. 1777 26 2008/07
- Molecular evolution of the modulator of chloroplast ATP synthase: origin of the conformational change dependent regulation T Hisabori,H Ueoka-Nakanishi,H Konno,F Koyama FEBS LETTERS 545 1 71 2003/06
- Structural and functional analysis of the intrinsic inhibitor subunit epsilon of F-1-ATPase from photosynthetic organisms Hiromasa Yagi,Hiroki Konno,Tomoe Murakami-Fuse,Atsuko Isu,Tomotaka Oroguchi,Hideo Akutsu,Mitsunori Ikeguchi,Toru Hisabori BIOCHEMICAL JOURNAL 425 85 2010/01
- 1P530 Regulation of rotation of cyanobacterial F1 ATPase(26. Single molecule biophysics,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) Konno Hiroki,Murakami Tomoe,Koyama Fumie,Nakanishi Hnayo_Ueoka,Hisabori Toru Seibutsu Butsuri 46 2 S279 2006
- Prodigiosins as a new group of H+/Cl- symporters that uncouple proton translocators T Sato,H Konno,Y Tanaka,T Kataoka,K Nagai,HH Wasserman,S Ohkuma JOURNAL OF BIOLOGICAL CHEMISTRY 273 34 21455 1998/08
- Molecular devices of chloroplast F-1-ATP synthase for the regulation T Hisabori,H Konno,H Ichimura,H Strotmann,D Bald BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1555 1-3 140 2002/09
- The bottom part of the subunit of F1-ATPase is important for catalytic activity Konno H,Murakami-Fuse T,Hisabori T Photosynthesis:Energy from the sun 5 601 2008/06
- Inverse regulation of rotation of F-1-ATPase by the mutation at the regulatory region on the gamma subunit of chloroplast ATP synthase H Ueoka-Nakanishi,Y Nakanishi,H Konno,K Motohashi,D Bald,T Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 279 16 16272 2004/04
- Inverse regulation of F-1-ATPase activity by a mutation at the regulatory region on the gamma subunit of chloroplast ATP synthase (vol 352, pg 783, 2000) H Konno,M Yodogawa,MT Stumpp,P Kroth,H Strotmann,K Motohashi,T Amano,T Hisabori BIOCHEMICAL JOURNAL 357 3 911 2001/08
- Prodigiosins Uncouple Mitochondrial and Bacterial F-ATPases: Evidence for Their H+/Cl- Symport Activity H. Konno,H. Matsuya,M. Okamoto,T. Sato,Y. Tanaka,K. Yokoyama,T. Kataoka,K. Nagai,H. H. Wasserman,S. Ohkuma Journal of Biochemistry 124 3 547 1998/09/01 ?
- The regulator of the F-1 motor: inhibition of rotation of cyanobacterial F-1-ATPase by the epsilon subunit Hiroki Konno,Tomoe Murakami-Fuse,Fumihiko Fujii,Fumie Koyama,Hanayo Ueoka-Nakanishi,Chan-Gi Pack,Masataka Kinjo,Toru Hisabori EMBO JOURNAL 25 19 4596 2006/10
- Probing conformations of the beta subunit of F0F1-ATP synthase in catalysis T Masaike,T Suzuki,SP Tsunoda,H Konno,M Yoshida BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 342 3 800 2006/04
- Analysis of the redox regulation of the chloroplast ATP synthase Ueoka-Nakanishi H. Konno,H,Hisabori T Photosynthesis: Fundamental Aspects to Global Perspectives 1 3 2005/03
- High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils Takahiro Watanabe-Nakayama,Masahiro Itami,Noriyuki Kodera,Toshio Ando,Hiroki Konno SCIENTIFIC REPORTS 6 28975 2016/07
- Redox regulation of CF1-ATPase involves interplay between the gamma-subunit neck region and the turn region of the beta DELSEED-loop Felix Buchert,Hiroki Konno,Toru Hisabori BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1847 4-5 441 2015/04
- Distinct Redox Behaviors of Chloroplast Thiol Enzymes and their Relationships with Photosynthetic Electron Transport in Arabidopsis thaliana Keisuke Yoshida,Yuta Matsuoka,Satoshi Hara,Hiroki Konno,Toru Hisabori PLANT AND CELL PHYSIOLOGY 55 8 1415 2014/08
- Reversible control of F-1-ATPase rotational motion using a photochromic Cross Mark ATP analog at the single molecule level Ei-Ichiro Sunamura,Takashi Kamei,Hiroki Konno,Nobuyuki Tamaoki,Toru Hisabori BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 446 1 358 2014/03
- Thiol Modulation of the Chloroplast ATP Synthase is Dependent on the Energization of Thylakoid Membranes Hiroki Konno,Takeshi Nakane,Masasuke Yoshida,Hanayo Ueoka-Nakanishi,Satoshi Hara,Toru Hisabori PLANT AND CELL PHYSIOLOGY 53 4 626 2012/04
- 1P303 Real-time observation of amyloid fibril formation of yeast prion Sup35 by high-speed atomic force microscopy(27. Bioimaging,Poster) Zhu Liwen,Konno Hiroki,Okuda Momoko,Kodera Noriyuki,Ando Toshio,Taguchi Hideki Seibutsu Butsuri 53 1 S156 2013
- Demonstration of correlative atomic force and transmission electron microscopy using actin cytoskeleton Y. Yamada,H. Konno,K. Shimabukuro Biophys Physicobiol. 14 111 2017
- Oxidation of a Cysteine Residue in Elongation Factor EF-Tu Reversibly Inhibits Translation in the Cyanobacterium Synechocystis sp PCC 6803 Rayakorn Yutthanasirikul,Takanori Nagano,Haruhiko Jimbo,Yukako Hihara,Takashi Kanamori,Takuya Ueda,Takamitsu Haruyama,Hiroki Konno,Keisuke Yoshida,Toru Hisabori,Yoshitaka Nishiyama JOURNAL OF BIOLOGICAL CHEMISTRY 291 11 5860 2016/03
- A Conformational Change of the gamma Subunit Indirectly Regulates the Activity of Cyanobacterial F-1-ATPase Ei-Ichiro Sunamura,Hiroki Konno,Mari Imashimizu,Mari Mochimaru,Toru Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 287 46 38695 2012/11
- The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue Toru Yoshida,Hideaki Tsuge,Hiroki Konno,Toru Hisabori,Yasushi Sugano FEBS JOURNAL 278 13 2387 2011/07
- Redox Regulation of Rotation of the Cyanobacterial F-1-ATPase Containing Thiol Regulation Switch Yusung Kim,Hiroki Konno,Yasushi Sugano,Toru Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 286 11 9071 2011/03
- Ubiquitin chain specificities of E6AP E3 ligase and its HECT domain Fuminori Kobayashi,Takumi Nishiuchi,Kento Takaki,Hiroki Konno Biochemical and Biophysical Research Communications 496 2 686 2018/02/05
- 1P297 Real time imaging of collagenase behavior by high speed atomic force microscopy(27. Bioimaging,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)) Nakayama Takahiro,Kodera Noriyuki,Kon'no Hiroki,Ando Toshio Seibutsu Butsuri 54 1 S190 2014
- Degradation of the synthetic dye amaranth by the fungus Bjerkandera adusta Dec 1: inference of the degradation pathway from an analysis of decolorized products Nichina Gomi,Shuji Yoshida,Kazutsugu Matsumoto,Masayuki Okudomi,Hiroki Konno,Toru Hisabori,Yasushi Sugano BIODEGRADATION 22 6 1239 2011/11
- Physiological Impact of Intrinsic ADP Inhibition of Cyanobacterial F0F1 Conferred by the Inherent Sequence Inserted into the gamma Subunit Ei-Ichiro Sunamura,Hiroki Konno,Mari Imashimizu-Kobayashi,Yasushi Sugano,Toru Hisabori PLANT AND CELL PHYSIOLOGY 51 6 855 2010/06
- Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation. Kobayashi M,Muramatsu K,Haruyama T,Uesugi H,Kikuchi A,Konno H,Noguchi N,Saito Y ACS omega 4 6 9603 2019/06
- 3P288 Investigation of hPrx2 oligomerization process by high-speed AFM(27. Bioimaging,Poster) Haruyama Takamitsu,Kodera Noriyuki,Konno Hiroki Seibutsu Butsuri 53 1 S259 2013
- Single -unit imaging of membrane protein-embedded nanodiscs from two oriented sides by high-speed atomic force microscopy T. Haruyama,Y. Sugano,N. Kodera,T. Uchihashi,T. Ando,Y. Tanaka,H. Konno,T. Tsukazaki Structure 27 1 152 2019/01
- Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge. Hisashi Tatebe,Chew Theng Lim,Hiroki Konno,Kazuhiro Shiozaki,Akira Shinohara,Takayuki Uchihashi,Asako Furukohri Nature communications 11 1 370 2020/01/17
- Ptdlns(3,5)P-2 mediates root hair shank hardening in Arabidopsis Tomoko Hirano,Hiroki Konno,Seiji Takeda,Liam Dolan,Mariko Kato,Takashi Aoyama,Takumi Higaki,Hisako Takigawa-Imamura,Masa H. Sato NATURE PLANTS 4 11 888 2018/11
- Intramolecular interaction suggests an auto suppression mechanism for the innate immune adaptor protein MyD88 M. Uno,T. Watanabe-Nakayama,H. Konno,K. Akagi,N. Tsutsumi,T. Fukao,M. Shirakawa,H. Ohnishi,H. Tochio Chemical Communications 54 87 12318 2018/10
- Negatively Charged Lipids Are Essential for Functional and Structural Switch of Human 2-Cys Peroxiredoxin II Takamitsu Haruyama,Takayuki Uchihashi,Yutaro Yamada,Noriyuki Kodera,Toshio Ando,Hiroki Konno Journal of Molecular Biology 430 5 602 2018/03/02
- The Chloroplast ATP Synthase Features the Characteristic Redox Regulation Machinery Toru Hisabori,Ei-Ichiro Sunamura,Yusung Kim,Hiroki Konno ANTIOXIDANTS & REDOX SIGNALING 19 15 1846 2013/11
- Common Evolutionary Origin for the Rotor Domain of Rotary Atpases and Flagellar Protein Export Apparatus Jun-ichi Kishikawa,Tatsuya Ibuki,Shuichi Nakamura,Astuko Nakanishi,Tohru Minamino,Tomoko Miyata,Keiichi Namba,Hiroki Konno,Hiroshi Ueno,Katsumi Imada,Ken Yokoyama PLOS ONE 8 5 e64692013 2013/05
- Nano-Scale Alignment of Proteins on a Flexible DNA Backbone Tatsuya Nojima,Hiroki Konno,Noriyuki Kodera,Kohji Seio,Hideki Taguchi,Masasuke Yoshida PLOS ONE 7 12 e52534 2012/12
- Regulation of F0F1-ATPase from Synechocystis sp PCC 6803 by gamma and epsilon Subunits Is Significant for Light/Dark Adaptation Mari Imashimizu,Gabor Bernat,Ei-Ichiro Sunamura,Martin Broekmans,Hiroki Konno,Kota Isato,Matthias Roegner,Toru Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 286 30 26595 2011/07
- Characterization of the Relationship between ADP- and epsilon-induced Inhibition in Cyanobacterial F-1-ATPase Hiroki Konno,Atsuko Isu,Yusung Kim,Tomoe Murakami-Fuse,Yasushi Sugano,Toru Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 286 15 13423 2011/04
- Dynamics of oligomer and amyloid fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy Hiroki Konno,Takahiro Watanabe-Nakayama,Takayuki Uchihashi,Momoko Okuda,Liwen Zhu,Noriyuki Kodera,Yousuke Kikuchi,Toshio Ando,Hideki Taguchi Proceedings of the National Academy of Sciences 117 14 7831 2020/04/07
- Visualization of Protein Assembly Dynamics by Using High-speed Atomic Force Microscopy WATANABE-NAKAYAMA Takahiro,KONNO Hiroki,YAMADA Masahito,ONO Kenjiro Seibutsu Butsuri 58 2 86 2018/04
- Unraveling the Host-Selective Toxic Interaction of Cassiicolin with Lipid Membranes and Its Cytotoxicity Kien Xuan Ngo,Phuong Doan N. Nguyen,Hirotoshi Furusho,Makoto Miyata,Tomomi Shimonaka,Nguyen Ngoc Bao Chau,Nguyen Phuong Vinh,Nguyen Anh Nghia,Tareg Omer Mohammed,Takehiko Ichikawa,Noriyuki Kodera,Hiroki Konno,Takeshi Fukuma,Nguyen Bao Quoc Phytopathology 112 7 1524 2022/07
- Self- and Cross-Seeding on α-Synuclein Fibril Growth Kinetics and Structure Observed by High-Speed Atomic Force Microscopy Takahiro Watanabe-Nakayama,Maika Nawa,Hiroki Konno,Noriyuki Kodera,Toshio Ando,David B. Teplow,Kenjiro Ono ACS Nano 14 8 9979 2020/08/25
- Author Correction: PtdIns(3,5)P2 mediates root hair shank hardening in Arabidopsis. Tomoko Hirano,Hiroki Konno,Seiji Takeda,Liam Dolan,Mariko Kato,Takashi Aoyama,Takumi Higaki,Hisako Takigawa-Imamura,Masa H Sato Nature plants 5 4 447 2019/04
- The SYP123-VAMP727 SNARE complex is involved in the delivery of inner cell wall components to the root hair shank in Arabidopsis Tomoko Hirano,Kazuo Ebine,Takashi Ueda,Takumi Higaki,Takahiro Nakayama,Hiroki Konno,Hisako Takigawa-Imamura,Masa H. Sato 2020/12/28
Conference Presentations
- Negatively charged lipids are an essential factor for functional switching of human 2-Cys peroxiredoxin II from peroxidase to molecular chaperone(2016/10/05)
- Functional extension of high-speed atomic force microscopy(2016/06)
- New insight into the functional switching of 2-cys peroxiredoxin revealed by high-speed atomic force microscopy(conference：Annual Biotechnology Congress)(2017/08/17)
- Correlative Atomic Force and Electron Microscopy toward Applications of Atomic Force Microscopy to Heterogeneous Systems(2016/10/12)
- Dynamic processes of oligomer and fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy(2016/10/06)
- New insight into the functional switching of 2-Cys Peroxiredoxin revealed by high-speed atomic force microscopy(2017/11/08)
Others
- Observation of the structural dynamics of HECT-type ubiquitin ligase using high-speed AFM 室郁弥,中山(渡辺)隆宏,古寺哲幸,安藤敏夫,紺野宏記 日本生体エネルギー研究会討論会講演要旨集 46th 2020
- Delta Glu(210)-ASp(211)-Glu(212) mutation in the regulatory region of chloroplast ATP synthase inverted redox regulation H Ueoka-Nakanishi,H Konno,K Motohashi,M Yoshida,T Hisabori PLANT AND CELL PHYSIOLOGY 44 S66 2003
- Investigation of formation process of Prx high molecular weight complexes and its physiological significance. 紺野宏記,羽澤勝治,芳坂綾子,佐々木理乃,矢幡信成,古寺哲幸,安藤敏夫 日本生体エネルギー研究会討論会講演要旨集 46th 2020
- Investigation of formation process of Prx high molecular weight complexes and its physiological significance. 紺野宏記,羽澤勝治,芳坂綾子,佐々木理乃,矢幡信成,古寺哲幸,安藤敏夫 日本生体エネルギー研究会討論会講演要旨集 45th 2019
- フェルラ酸‐α‐シクロデキストリン包接複合体の物理化学特性と高速AFMによる解析 鈴木瑞季,中山隆宏,紺野宏記,生田直子,寺尾啓二,松郷誠一 シクロデキストリンシンポジウム講演要旨集 34th 184‐185 2017/08
- Nano-Space Video Imaging Reveals Structural Dynamics of Fibrous Protein Assembly and Relevant Enzymes Takahiro Watanabe-Nakayama,Noriyuki Kodera,Hiroki Konno,Kenjiro Ono,David B. Teplow,Masahito Yamada,Toshio Ando BIOPHYSICAL JOURNAL 112 3 469A 2017/02
- Conformations of the catalytic subunit beta in F0F1-ATP synthase T Masaike,T Suzuki,SP Tsunoda,H Konno,J Suzuki,M Yoshida BIOPHYSICAL JOURNAL 88 1 505A 2005/01
- Inverse regulation of F-1-ATPase activity by a mutation at the regulatory region on the gamma subunit of chloroplast ATP synthase H Konno,M Yodogawa,MT Stumpp,P Kroth,H Strotmann,K Motohashi,T Amano,T Hisabori BIOCHEMICAL JOURNAL 352 3 783 2000/12
- Relation between ADP inhibition and e inhibition of rotation of the chloloplast-type F-1-ATPase T. Hisabori,T. Murakarmi,H. Konno PHOTOSYNTHESIS RESEARCH 91 2-3 194 2007/02
- Observation of the structural dynamics associated with ubiquitination of HECT-type ubiquitin ligase using high-speed AFM 室郁弥,中山(渡辺)隆宏,古寺哲幸,安藤敏夫,紺野宏記 日本生体エネルギー研究会討論会講演要旨集 45th 2019
- Visualization of Protein Assembly Dynamics by Using High-speed Atomic Force Microscopy 中山隆宏,紺野宏記,山田正仁,小野賢二郎 生物物理(Web) 58 2 086‐088(J‐STAGE) 2018/03
- Conformational change of the gamma subunit regulates the ATP hydrolysis activity of cyanobacterial ATP synthase E. -I. Sunamura,H. Konno,M. Imashimizu,M. Mochimaru,T. Hisabori BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1817 S24 2012/10
- Redox regulation of thermophilic bacterial F0F1 containing the regulatory region of chloroplast ATP synthase H Konno,T Suzuki,D Bald,M Yoshida,H Ichimura,T Hisabori PLANT AND CELL PHYSIOLOGY 43 S25 2002
- Single molecule analysis of the tentoxin-induced molecular processes of inhibition and stimulation of CF1 Erik Meiss,Hiroki Konno,Georg Groth,Toru Hisabori BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1777 S19 2008/07
- Significance of the epsilon subunit in the thiol modulation of chloroplast ATP synthase H Konno,T Suzuki,D Bald,M Yoshida,T Hisabori BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 318 1 17 2004/05
- Study on the formation mechanism of peroxiredoxin high molecular weight complex with lipid and nucleotide. 佐々木理乃,神代真実,古寺哲幸,安藤敏夫,紺野宏記 日本生体エネルギー研究会討論会講演要旨集 45th 2019
- Secトランスロコンの1ユニット再構成系の構築と動的探査 菅野泰功,春山隆充,田中良樹,紺野宏記,塚崎智也 日本蛋白質科学会年会プログラム・要旨集 16th 45 2016/05/19
- 高速AFM観察によるコラーゲン分解におけるコラゲナーゼのダイナミクスの解明 中山隆宏,古寺哲幸,紺野宏記,安藤敏夫 日本分子生物学会年会プログラム・要旨集(Web) 36th 1P-0369 (WEB ONLY) 2013
- Regulation of rotation of chloroplast ATP synthase using regulatory devices KONNO Hiroki,KOBAYASHI IMASHIMIZU Mari,SUNAMURA Ei-ichiro,HISABORI Toru Bioscience & industry 68 4 253 2010/07/01
- Regulation of rotation of cyanobacterial F-1 ATPase H Konno,T Murakami,F Koyama,H Nakanishi,M Yoshida,T Hisabori PLANT AND CELL PHYSIOLOGY 47 S105 2006
- Molecular processes of inhibition and stimulation of ATP synthase caused by the phytotoxin tentoxin Erik Meiss,Hiroki Konno,Georg Groth,Toru Hisabori JOURNAL OF BIOLOGICAL CHEMISTRY 283 36 24594 2008/09
- 免疫シグナルハブタンパク質MyD88の分子内相互作用解析 宇野雅俊,中山隆宏,紺野宏記,大西秀典,白川昌宏,杤尾豪人 日本生化学会大会(Web) 90th ROMBUNNO.1P‐0122 (WEB ONLY) 2017/12
- Secタンパク質膜透過装置の活写にむけて 塚崎智也,春山隆充,菅野泰功,田中良樹,紺野宏記 日本蛋白質科学会年会プログラム・要旨集 14th 5 2014/05/26
- 過渡的複合体解析の為のDNA構造によるタンパク質の連結とナノスケールの配列手法の開発 野島達也,紺野宏記,古寺哲幸,清尾康志,田口英樹,吉田賢右 日本蛋白質科学会年会プログラム・要旨集 12th 72 2012/05/31
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Biochemistry 1(2017)
○Research Work in Biology(2)(2017)
○Research Seminar in Biology (2)(2017)
○Plant Physiology Lab(2017)
○Research Seminar in Biology (1)(2017)
○Research Work in Biology(1)(2017)
○Biochemistry 1(2016)
○Research Work in Biology(1)(2016)
○Research Seminar in Biology (1)(2016)
○Plant Physiology Lab(2016)
○Research Work in Biology(2)(2016)
○Research Seminar in Biology (2)(2016)
Classes (Graduate Schools)
○Bioenergetics(2017)
○Advanced Single-molecule Nanobiology(2017)
○Systems structure and function in biomolecules A(2017)
○Bioenergetics(2017)
○Bioenergetics(2017)
○Bioenergetics(2017)
○Systems structure and function in biomolecules A(2016)
○Advanced Single-molecule Nanobiology(2016)
○Systems structure and function in biomolecules B(2016)
○Bioenergetics(2016)