last modified：2025/04/03
Associate Professor FUKUYOSHI Shuichi
Faculty, Affiliation
Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Division of Health Sciences, Graduate School of Phamaceutical Science
Division of Pharmaceutical Sciences, Graduate School of Medical Science
School of Pharmaceutical Sciences, College of Medical, Pharmaceutical and Health Sciences
School of Pharmacy, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Physical Chemistry TEL:076-234-4483 FAX:076-234-4484
Academic Background
【Academic background(Doctoral/Master's Degree)】
The University of Tokushima Doctor Graduate School, Division of Pharmaceutical Sciences 200103 Completed
【Academic background(Bachelor's Degree)】
The University of Tokushima 199603
【Degree】
Ph.D
Career
Year & Month of Birth
1973/02
Academic Society
The pharmaceutical society of japan
The chemical society of Japan
The Japanese Photochemistry Association
Award
Specialities
Organic chemistry
Speciality Keywords
Research Themes
stereocontroll by photochromic compounds
Books
Papers
- Theoretical study on keto–enol tautomerisation of glutarimide for exploration of the isomerisation reaction pathway of glutamic acid in proteins using density functional theory Shuichi Fukuyoshi, Tomoki Nakayoshi, Ohgi Takahashi, Akifumi Oda Molecular Physics 115 5 560 2017
- Influence of the Conformation of Methoxy-(2-naphthyl)acetates (2NMA Ester) on Their Chemical Reactions Shu-ichi Fukuyoshi, Takashi Ooi, Takenori Kusumi CHEMICAL & PHARMACEUTICAL BULLETIN 48 8 1208-1210 2000/04
- Acceleration of Tributyltin Hydride Reduction of Phenethyl Iodide and m-Methoxybenzyl Bromide by a Strong Magnetic Field Shu-ichi Fukuyoshi, Takenori Kusumi CHEMISTRY LETTERS 230-231 2001/01
- Autoxidation of linoleic acid in a strong magnetic field (9.4 T) Masahiro Inotani,Shuichi Fukuyoshi,Takenori Kusumi TETRAHEDRON LETTERS 42 7451-7452 2001/08
- Molecular Dynamics Simulations to Investigate the Influences of Amino Acid Mutations on Protein Three-Dimensional Structures of Cytochrome P450 2D6.1, 2, 10, 14A, 51, and 62 Shuichi Fukuyoshi, Masahiro Kometani, Yurie Watanabe, Akifumi oda PLOS ONE 11 4 e0152946 2016
- 9.4 T and 7.05 T Magnetic Fields Accelerate a Radical Oxidation Reaction with a Hypervalent(tert-Butylperoxy)iodine Kaori Iba,Shu-ichi Fukuyoshi,Takenori Kusumi CHEMISTRY LETTERS 33 6 716-717 2004/07
- Prediction of three-dimensional structures and structural flexibilities of wild-type and mutant cytochrome P450 1A2 using molecular dynamics simulations Yurie Watanabea, Shuichi Fukuyoshi, Masahiro Hiratsuka, Noriyuki Yamaotsu, Shuichi Hirono, Ohgi Takahashi, Akifumi Oda Journal of Molecular Graphics and Modelling 68 48 2016
- A Novel Clerodane Diterpene from Vitex cofassus Faradiba Abdul Rasyid, Shuichi Fukuyoshi, Hirokazu Ando, Katsunori Miyake, Toshiyuki Atsumi, Tetsuo Fujie, Yohei Saito, Masuo Goto, Tomohiro Shinya, Masayuki Mikage, Yohei Sasaki, Kyoko Nakagawa-Goto Chemical and Pharmaceutical Bulletin 65 1 116 2017
- Corymbulosins D−H, 2‐Hydroxy- and 2‐Oxo-clerodane Diterpenes from the Bark of Laetia corymbulosa Airi Suzuki, Yohei Saito, Shuichi Fukuyoshi, Masuo Goto, Katsunori Miyake, David J. Newman, Barry R. O’Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto Journal of Natural Products in press 2017
- Determination of molecular force field parameters for nitronyl nitroxide derivatives using quantum chemical calculations Akifumi Oda, Shuichi Fukuyoshi, Eiji Kurimoto Polyhedron in press 2017
- Comparison of photoreactions of flutamide in acetonitrile and 2-propanol solvents in the absence of cage-forming compounds Watanabe, Yurie;Fukuyoshi, Shuichi;Oda, Akifumi JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 298 55-61 2015/01/01
- Evaluations of the conformational search accuracy of CAMDAS using experimental three-dimensional structures of protein-ligand complexes A. Oda, N. Yamaotsu, S. Hirono, Y. Takano, S. Fukuyoshi, R. Nakagaki Journal of Physics: Conference Series 454 012028 2012/10
- Magnetic field effect on photosensitized oxidation of 1,3-diphenyliso- benzofuran in SDS micellar solution C. Udagawa, T. Izutani, S. Yamamoto, S. Morimoto, S. Fukuyoshi, R. Nakagaki JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 238 16 2012/06
- Photochemistry of flutamide in various media: Investigation of the reaction mechanism as revealed by external magnetic field effects on product yields. C. Udagawa, S. Fukuyoshi, S. Morimoto, Y. Tanimoto, R. Nakagaki, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 226 1 57 2011/12
- Crystal Structure of 2-[1-(2,4-Dinitrophenyl)ethyl]-1,10-Phenanthroline Shuichi Fukuyoshi, Takashi Ooi and Ryoichi Nakagaki X-ray Structure Analysis Online 26 55 2010/07
- Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes Takahashi H., Miyaki S., Onouchi H., Motomura T., Idesako N., Takahashi A., Fukuyoshi S., Endo T., Satou K., Naito S., Itoh M bioRxiv 2020
- Excess sterols disrupt plant cellular activity by inducing stress-responsive gene expression Shimada Takashi L, Yamaguchi Katsushi, Shigenobu Shuji, Takahashi Hiro, Murase Masataka, Fukuyoshi Shuichi, Hara-Nishimura Ikuko Journal of Plant Research 0123456789 2020
- Computational studies on water-catalyzed mechanisms for stereoinversion of glutarimide intermediates formed from glutamic acid residues in aqueous phase Nakayoshi Tomoki, Fukuyoshi Shuichi, Kato Koichi, Kurimoto Eiji, Oda Akifumi International Journal of Molecular Sciences 20 10 2410 2019
- Isolation, structure elucidation, and antiproliferative activity of butanolides and lignan glycosides from the fruit of hernandia nymphaeifolia Aimaiti Simayijiang, Saito Yohei, Fukuyoshi Shuichi, Goto Masuo, Miyake Katsunori, Newman David J., O’Keefe Barry R., Lee Kuo Hsiung, Nakagawa-Goto Kyoko Molecules 24 21 4005 2019
- Three dimensional structures of putative, primitive proteins to investigate the origin of homochirality Oda Akifumi, Nakayoshi Tomoki, Kato Koichi, Fukuyoshi Shuichi, Kurimoto Eiji Scientific Reports 9 1 1-8 2019
- Draft Genome Sequence of Aspergillus terreus High-Itaconic-Acid-Productivity Mutant TN-484 Kanamasa Shin, Minami Tomoyuki, Okabe Mitsuyasu, Park Enoch Y., Fujimoto Tsukasa, Takahashi Anna, Murase Masataka, Fukuyoshi Shuichi, Oda Akifumi, Satou Kenji, Takahashi Hiro Microbiology Resource Announcements 8 49 6-7 2019
- Draft Genome Sequence of Saccharomyces cerevisiae Strain Pf-1, Isolated from Prunus mume Kanamasa Shin, Yamaguchi Daiki, Machida Chiyoko, Fujimoto Tsukasa, Takahashi Anna, Murase Masataka, Fukuyoshi Shuichi, Oda Akifumi, Satou Kenji, Takahashi Hiro Microbiology Resource Announcements 8 46 1-2 2019
- Spiro[3.5]nonenyl Meroterpenoid Lactones, Cryptolaevilactones G-L, an Ionone Derivative, and Total Synthesis of Cryptolaevilactone M from Cryptocarya laevigata Tsurumi Fumika, Miura Yuta, Nakano Misaki, Saito Yohei, Fukuyoshi Shuichi, Miyake Katsunori, Newman David J., O'Keefe Barry R., Lee Kuo Hsiung, Nakagawa-Goto Kyoko Journal of Natural Products 82 9 2368-2378 2019
- Computational studies on non-succinimide-mediated stereoinversion mechanism of aspartic acid residues assisted by phosphate Nakayoshi, Tomoki Fukuyoshi, Shuichi Takahashi, Ohgi Oda, Akifumi Molecular Physics 116 5-6 686-696 2018
- Influences of conformations of peptides on stereoinversions and/or isomerizations of aspartic acid residues Oda, Akifumi Nakayoshi, Tomoki Fukuyoshi, Shuichi Kurimoto, Eiji Takahashi, Ohgi Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1866 7 783-788 2018
- Triazine-Based Cationic Leaving Group: Synergistic Driving Forces for Rapid Formation of Carbocation Species Fujita, Hikaru Kakuyama, Satoshi Fukuyoshi, Shuichi Hayakawa, Naoko Oda, Akifumi Kunishima, Munetaka The Journal of Organic Chemistry 83 8 4568-4580 2018
- Validation of molecular force field parameters for peptides including isomerized amino acids Oda, Akifumi Nakayoshi, Tomoki Fukuyoshi, Shuichi Kurimoto, Eiji Yamaotsu, Noriyuki Hirono, Shuichi Takahashi, Ohgi Chirality 30 4 332-341 2018
- Prediction of the three-dimensional structures of histone deacetylase 1 complexed with romidepsin and FK-A5 Oda, A. Kato, K. Morino, M. Nakayoshi, T. Fukuyoshi, S. Saijo, K. Ishioka, C. Kurimoto, E. Journal of Physics: Conference Series 1136 1 012019 2018
- Computational studies on the water-catalyzed stereoinversion mechanism of glutamic acid residues in peptides and proteins Nakayoshi, Tomoki Kato, Koichi Fukuyoshi, Shuichi Takahashi, Ohgi Kurimoto, Eiji Oda, Akifumi Chirality 30 5 527-535 2018
- Effect of the Arg456His mutation on the three-dimensional structure of cytochrome P450 1A2 predicted by molecular dynamics simulations Watanabe, Y. Kato, K. Fukuyoshi, S. Hiratsuka, M. Yamaotsu, N. Hirono, S. Gouda, H. Oda, A. Journal of Physics: Conference Series 1136 1 012023 2018
- Draft Genome Sequence of Saccharomyces cerevisiae Strain Hm-1, Isolated from Cotton Rosemallow Takahashi, Hiro Sakagawa, Erika Sakakibara, Ikuya Machida, Chiyoko Miyaki, Shido Takahashi, Anna Onai, Shinnosuke Fukuyoshi, Shuichi Ohta, Akinori Satou, Kenji Kanamasa, Shin Microbiology Resource Announcements 7 13 1-2 2018
- Comparison of the activation energy barrier for succinimide formation from α- and β-aspartic acid residues obtained from density functional theory calculations Nakayoshi, Tomoki Kato, Koichi Fukuyoshi, Shuichi Takahashi, Ohgi Kurimoto, Eiji Oda, Akifumi Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1866 7 759-766 2018
- Draft Genome Sequence of Trebouxiophyceae sp. Strain KSI-1, Isolated from an Island Hot Spring Takahashi, Hiro Tanaka, Satoshi Hayashi, Shuhei Miyaki, Shido Takahashi, Anna Onai, Shinnosuke Fukuyoshi, Shuichi Miyasaka, Hitoshi Microbiology Resource Announcements 7 16 1-2 2018
- A Novel Clerodane Diterpene from Vitex cofassus Faradiba Abdul Rasyid, Shuichi Fukuyoshi, Hirokazu Ando, Katsunori Miyake, Toshiyuki Atsumi, Tetsuo Fujie, Yohei Saito, Masuo Goto, Tomohiro Shinya, Masayuki Mikage, Yohei Sasaki, Kyoko Nakagawa-Goto Chemical and Pharmaceutical Bulletin 65 1 116 2017
- Validation of Molecular Dynamics Simulations for Prediction of Three-Dimensional Structures of Small Proteins Koichi Kato, Tomoki Nakayoshi, Shuichi Fukuyoshi, Eiji Kurimoto, Akifumi Oda Molecules 22 10 1716 2017
- Investigation of substrate recognition for cytochrome P450 1A2 mediated by water molecules using docking and molecular dynamics simulations Yurie Watanabe, Shuichi Fukuyoshi, Koichi Kato, Masahiro Hiratsuka, Noriyuki Yamaotsu, Shuichi Hirono, Hiroaki Gouda, Akifumi Oda Journal of Molecular Graphics and Modelling 74 326 2017
- Corymbulosins I–W, Cytotoxic Clerodane Diterpenes from the Bark of Laetia corymbulosa Simayijiang Aimaiti, Airi Suzuki, Yohei Saito, Shuichi Fukuyoshi, Masuo Goto, Katsunori Miyake, David J. Newman, Barry R. O’Keefe, Kuo-Hsiung Lee, and Kyoko Nakagawa-Goto The Journal of Organic Chemistry 83 2 951 2018
- Prediction of binding modes between protein L-isoaspartyl (D-aspartyl) O-methyltransferase and peptide substrates including isomerized aspartic acid residues using in silico analytic methods for the substrate screening Akifumi Oda, Ikuhiko Noji, Shuichi Fukuyoshi, Ohgi Takahashi Journal of Pharmaceutical and Biomedical Analysis 116 116 2015
- Investigation of photoreaction for 2-nitrobenzofuran and its 3-methyl derivative Yurie Watanabe, Tomohiro Tanaka, Shuichi Fukuyoshi, Akifumi Oda J. Photochem. Photobiol. A 311 127 2015
- Effects of initial settings on computational protein-ligand docking accuracies for several docking programs Akifumi Oda, Noriyuki Yamaotsu, Shuichi Hirono, Yurie Watanabe, Shuichi Fukuyoshi, Ohgi Takahashi Mol. Simul. 41 10-12 1027 2015
- Predicting three-dimensional conformations of peptides constructed of only glycine, alanine, aspartic acid, and valine Akifumi Oda, Shuichi Fukuyoshi Orig. Life Evol. Biosph 45 183 2015
Conference Presentations
- Computational study on bond formation of a primitive protein including D-amino acid(conference：IDAR2017 (The 3rd International Conference of D-Amino Acid Research))(2017/07/10)
- Computational study of racemization reaction of the aspartic acid residue in protein(conference：The Pharmaceutical Society of Japan 137th Annual Meeting)(2017/03/24)
- Evaluations of Density Functionals and Solvation Effect for Racemization Reaction of Amino Acid Residues (conference：57th Sanibel Symposium)(2017/02/19)
- Computational study of isomerization reaction route of the aspartic acid (conference：The 44th Symposium on Structural Activity Relationship)(2016/11/16)
- タンパク質中グルタミン酸異性化反応経路に対する計算化学的考察(conference：12th Annual Meeting_DAA)(2016/09/14)
- Computational study of isomerization reaction route of glutamic acid residue(conference：The Pharmaceutical Society of Japan 136th Annual Meeting)(2016/03/26)
- Theoretical study on keto-enol tautomerization of glutarimide for exploration of the isomerization reaction pathway of glutamic acid in proteins using density functional theory(conference：56th Sanibel Symposium)(2016/02/18)
- Solvent and substituent effect on lifetime of colored form of dinitrobenzylpyridine derivatives(conference：Pacifichem 2015)(2015/12/15)
- Photochromism of dinitrobenzylpyridine derivatives(conference：The Pharmaceutical Society of Japan 135th Annual Meeting)(2015/03/28)
Others
- Chemistry and Education The Chemical Society of Japan 59 4 206 2011/04
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「ゲノムジャンク領域にコードされる機能ペプチドの制御機構の情報学的推定と実験的検証」(2021-2023)
○「ジニトロベンジル基をもつ複素環化合物の光反応」(2008-)
○「フォトクロミック分子の立体制御」(2009-)
○「光と磁場による絶対不斉合成」(2008-)
○「フォトクロミズムを利用した不斉コントロール」(2008-)
○「ジニトロベンジルピリジン誘導体のフォトクロミズム」(2008-)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Physical Chemistry 1(2022)
○Physical Chemistry 1(2022)
○Physical Chemistry 1(2022)
○Physical Chemistry 2(2022)
○Physical Chemistry 2(2022)
○Physical Chemistry 2(2022)
○Physical Chemistry 3(2022)
○Physical Chemistry 3(2022)
○Physical Chemistry 3(2022)
○Physical Chemistry 3(2022)
○Physical Chemistry 3(2022)
○Physical Chemistry 3(2022)
○Experiments in Analysis and Measurements 1(2022)
○Experiments in Analysis and Measurements 1(2022)
○Basic Medical and Pharmaceutical Sciences Rotation Practice（Course in Pharmaceutical Sciences）Ⅰ(2022)
○Basic Analytical Chemistry(2022)
○Integrated Science(2022)
○Analytical, Environmental and Physical Sciences(2022)
○Analytical, Environmental and Physical Sciences(2022)
○Analytical Chemistry 1(2022)
○Analytical Chemistry 1(2022)
○Analytical Chemistry 1(2022)
○Analytical Chemistry 1(2022)
○Physical Chemistry 1(2021)
○Physical Chemistry 2(2021)
○Physical Chemistry 3(2021)
○Experiments in Analysis and Measurements 1(2021)
○Analytical, Environmental and Physical Sciences(2021)
○Introduction to Data Science(2021)
○Analytical Chemistry 1(2021)
○Analytical Chemistry 1(2021)
○World of Chemistry(2019)
○Physical Chemistry 1(2019)
○Physical Chemistry 2(2019)
○Physical Chemistry 3(2019)
○Experiments in Analysis and Measurements 1(2019)
○Freshman Seminar I(2019)
○Analytical, Environmental and Physical Sciences(2019)
○Physical Chemistry 2(2017)
○Physical Chemistry 3(2017)
○Experiments in Analysis and Measurements 1(2017)
○Physical Chemistry 1(2017)
○World of Chemistry(2017)
○Analytical， Environmental and Physical Sciences(2017)
○World of Chemistry(2016)
○World of Chemistry(2016)
○Experiments in Analysis and Measurements 2(2016)
○Physical Chemistry 2(2016)
○Analytical， Environmental and Physical Sciences(2016)
○Physical Chemistry 3(2016)
○Physical Chemistry 3(2016)
○Physical Chemistry 1(2016)
Classes (Graduate Schools)
○Advanced Course of Pharmachemistry(2022)
○Introduction to Discovering Molecular Probes b(2022)
○Advanced Seminar on Pharmachemistry(2022)
○Advanced Seminar on Pharmachemistry(2022)