last modified：2025/05/20
Assistant Professor NAKANO, Yasuhiro
Faculty, Affiliation
Institute for Frontier Science Initiative
College and School Educational Field
Laboratory
Integrated Systems of Aging Research Unit, Institute for Frontier Science Initiative
Academic Background
Career
Year & Month of Birth
Academic Society
Award
○AbbVie Award(2020/11)
○AbbVie Award(2020/11)
○Top Downloaded Article 2017-2018, Hepatology Communications(2019/06)
○Presidential Poster of Distinction(2018/11)
○Presidential Poster of Distinction(2016/11)
○Best Poster Award(2023/10)
Specialities
Speciality Keywords
Research Themes
Books
Papers
- Functional diversity of senescent cells in driving ageing phenotypes and facilitating tissue regeneration Yasuhiro Nakano,Yoshikazu Johmura The Journal of Biochemistry 177 3 189 2025/01/06
- Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state. Yasuhiro Nakano,Eiko Saijou,Tohru Itoh,Minoru Tanaka,Atsushi Miyajima,Taketomo Kido Scientific Reports 14 1 8536 2024/04/12
- Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis Sonal Sinha,Satoka Aizawa,Yasuhiro Nakano,Alexander Rialdi,Hye Yeon Choi,Rajan Shrestha,Stephanie Q. Pan,Yibu Chen,Meng Li,Audrey Kapelanski-Lamoureux,Gregory Yochum,Linda Sher,Satdarshan Paul Monga,Anthoula Lazaris,Keigo Machida,Michael Karin,Ernesto Guccione,Hidekazu Tsukamoto Nature Communications 14 1 2023/05/08
- Targeting cellular senescence as a therapeutic approach in non-alcoholic steatohepatitis Yasuhiro Nakano,Yoshikazu Johmura Annals of Hepatology 28 2 100900 2023/03
- Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice Yasuhiro Nakano,Sachie Nakao,Minako Sueoka,Daigo Kasahara,Yuri Tanno,Hideaki Sumiyoshi,Tohru Itoh,Atsushi Miyajima,Katsuto Hozumi,Yutaka Inagaki Communications Biology 5 1 85 2022/01
- A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice. Yasuhiro Nakano,Akihide Kamiya,Hideaki Sumiyoshi,Kota Tsuruya,Tatehiro Kagawa,Yutaka Inagaki Hepatology 71 4 1437 2020/04
- Identification of a novel alpha-fetoprotein-expressing cell population induced by the Jagged1/Notch2 signal in murine fibrotic liver. Yasuhiro Nakano,Sachie Nakao,Hideaki Sumiyoshi,Kenichiro Mikami,Yuri Tanno,Minako Sueoka,Daigo Kasahara,Hiroshi Kimura,Tadashi Moro,Akihide Kamiya,Katsuto Hozumi,Yutaka Inagaki Hepatology Communications 1 3 215 2017/05
- Disappearance of centroacinar cells in the Notch ligand-deficient pancreas. Yasuhiro Nakano,Naoko Negishi,Seiho Gocho,Tetsuya Mine,Yuri Sakurai,Masaki Yazawa,Koichiro Abe,Hideo Yagita,Sonoko Habu,Ryoichiro Kageyama,Yoshiya Kawaguchi,Katsuto Hozumi Genes to Cells 20 6 500 2015/06
- Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice. Sota Kodama,Yasuhiro Nakano,Koji Hirata,Kenichiro Furuyama,Masashi Horiguchi,Takeshi Kuhara,Toshihiko Masui,Michiya Kawaguchi,Maureen Gannon,Christopher V E Wright,Shinji Uemoto,Yoshiya Kawaguchi Scientific Reports 6 21211 2016/02/18
- Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo. Satotaka Omori,Teh-Wei Wang,Yoshikazu Johmura,Tomomi Kanai,Yasuhiro Nakano,Taketomo Kido,Etsuo A Susaki,Takuya Nakajima,Shigeyuki Shichino,Satoshi Ueha,Manabu Ozawa,Kisho Yokote,Soichiro Kumamoto,Atsuya Nishiyama,Takeharu Sakamoto,Kiyoshi Yamaguchi,Seira Hatakeyama,Eigo Shimizu,Kotoe Katayama,Yasuhiro Yamada,Satoshi Yamazaki,Kanako Iwasaki,Chika Miyoshi,Hiromasa Funato,Masashi Yanagisawa,Hiroo Ueno,Seiya Imoto,Yoichi Furukawa,Nobuaki Yoshida,Kouji Matsushima,Hiroki R Ueda,Atsushi Miyajima,Makoto Nakanishi Cell Metabolism 32 5 814 2020/11/03
- Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling. Yuta Koui,Misao Himeno,Yusuke Mori,Yasuhiro Nakano,Eiko Saijou,Naoki Tanimizu,Yoshiko Kamiya,Hiroko Anzai,Natsuki Maeda,Luyao Wang,Tadanori Yamada,Yasuyuki Sakai,Ryuichiro Nakato,Atsushi Miyajima,Taketomo Kido Stem Cell Reports 16 12 3050 2021/12/14
Conference Presentations
- A novel deactivation factor of fibrogenic hepatic stellate cells induces regression of liver fibrosis(conference：Cold Spring Harbor Asia Conference)(2019/12/11)
- Behavior of Reactive Cholangiocytes in the Tissue Repair Stage from Chronic Liver Injury(conference：APASL STC 2021 Osaka)(2021/09/02)
- Treatment strategy for liver fibrosis using a novel deactivation factor of fibrogenic hepatic stellate cells(conference：JSH International Liver Conference 2019)(2019/10/01)
- Regression of Liver Fibrosis Induced by a Novel Deactivation Factor of Fibrogenic Hepatic Stellate Cells(conference：American Association for the Study of Liver Diseases (AASLD) - Liver meeting 2018)(2019/11/10)
- Treatment Strategy of Liver Fibrosis Using Novel Reprogramming Factor(s) of Fibrogenic Hepatic Stellate Cells(conference：American Association for the Study of Liver Diseases (AASLD) - Liver meeting 2018)(2018/11/08)
- Differential Notch Signaling Modulates Experimental Hepatic Carcinogenesis in Mice(conference：American Association for the Study of Liver Diseases - Liver meeting 2017)(2017/10/22)
- Contribution of Jagged1/Notch Signaling to Murine Fibrotic Liver Regeneration through Possible Dedifferentiation of Mature Hepatocytes(conference：American Association for the Study of Liver Diseases - Liver meeting 2016)(2016/11/11)