Professor Kazuo Okamoto
Faculty, Affiliation
Cancer Research Institute Division of Immune Environment Dynamics
Professor
College and School Educational Field
Laboratory
Division of Immune Environment Dynamics TEL:076-264-6726
Academic Background
【Academic background(Doctoral/Master's Degree)】
Kyoto University Doctor Graduate School of Biostudies, 200603 Completed
【Academic background(Bachelor's Degree)】
Kyoto University 200003
Career
Kyoto University Faculty of Science(-2000/03)
Kyoto University Graduate School of Biostudies(2000/04-2006/03)
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences(2006/04-2007/03)
(2007/04-2010/03)
(2010/04-2015/03)
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences(2010/08-2012/04)
The University of Tokyo Graduate School of Medicine(2012/05-2016/04)
The University of Tokyo Graduate School of Medicine(2016/05-2024/03)
Kanazawa University Cancer Research Institute Professor(2024/04-)
Year & Month of Birth
1977/05
Academic Society
JAPANESE SOCIETY FOR IMMUNOLOGY (JSI)
JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH
THE JAPANAESE SOCIETY OF INFLAMMATION AND REGENERATION
JAPANESE SOCIETY FOR OSTEOIMMUNOLOGY
JAPAN COLLEGE OF RHEUMATOLOGY
Award
JAPAN COLLEGE OF RHEUMATOLOGY
JAPAN COLLEGE OF RHEUMATOLOGY
JAPAN COLLEGE OF RHEUMATOLOGY
Specialities
Immunology、Experimental pathology
Speciality Keywords
Immunology,Oncology,Osteoimmunology,Autoimmune disease,rheumatoid arthritis
Research Themes
Books
- Kazuo OKAMOTO “Osteoimmunology”, Genetics of Bone Biology and Skeletal Disease, Second Edition ACADEMIC PRESS/ ELSEVIER 2017
Papers
- Effect of T cells on bone Kazuo Okamoto,Hiroshi Takayanagi Bone 168 116675 2023/03
- Role of RANKL in cancer development and metastasis. Kazuo Okamoto Journal of bone and mineral metabolism 39 1 71 2021/01
- Soluble RANKL is physiologically dispensable but accelerates tumour metastasis to bone. Tatsuo Asano,Kazuo Okamoto,Yuta Nakai,Masanori Tsutsumi,Ryunosuke Muro,Ayako Suematsu,Kyoko Hashimoto,Tadashi Okamura,Shogo Ehata,Takeshi Nitta,Hiroshi Takayanagi Nature metabolism 1 9 868 2019/09
- Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis. Yuta Nakai,Kazuo Okamoto,Asuka Terashima,Shogo Ehata,Jun Nishida,Takeshi Imamura,Takashi Ono,Hiroshi Takayanagi Bone research 7 1 2019
- Arginine methylation controls the strength of γc-family cytokine signaling in T cell maintenance. Inoue M,Okamoto K,Terashima A,Nitta T,Muro R,Negishi-Koga T,Kitamura T,Nakashima T,Takayanagi H Nature immunology 19 11 1265 2018/11
- Osteoimmunology: The conceptual framework unifying the immune and skeletal systems Kazuo Okamoto,Tomoki Nakashima,Masahiro Shinohara,Takako Negishi-Koga,Noriko Komatsu,Asuka Terashima,Shinichiro Sawa,Takeshi Nitta,Hiroshi Takayanagi Physiological Reviews 97 4 1295 2017/10/01
- Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency Asuka Terashima,Kazuo Okamoto,Tomoki Nakashima,Shizuo Akira,Koichi Ikuta,Hiroshi Takayanagi IMMUNITY 44 6 1434 2016/06
- Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System Matteo M. Guerrini,Kazuo Okamoto,Noriko Komatsu,Shinichiro Sawa,Lynett Danks,Josef M. Penninger,Tomoki Nakashima,Hiroshi Takayanagi IMMUNITY 43 6 1174 2015/12
- IL-17-producing gamma delta T cells enhance bone regeneration Takehito Ono,Kazuo Okamoto,Tomoki Nakashima,Takeshi Nitta,Shohei Hori,Yoichiro Iwakura,Hiroshi Takayanagi NATURE COMMUNICATIONS 7 10928 2016/03
- Pathogenic conversion of Foxp3(+) T cells into T(H)17 cells in autoimmune arthritis Noriko Komatsu,Kazuo Okamoto,Shinichiro Sawa,Tomoki Nakashima,Masatsugu Oh-hora,Tatsuhiko Kodama,Sakae Tanaka,Jeffrey A. Bluestone,Hiroshi Takayanagi NATURE MEDICINE 20 1 62 2014/01
- IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors. Kazuo Okamoto,Yoshiko Iwai,Masatsugu Oh-Hora,Masahiro Yamamoto,Tomohiro Morio,Kazuhiro Aoki,Keiichi Ohya,Anton M Jetten,Shizuo Akira,Tatsushi Muta,Hiroshi Takayanagi Nature 464 7293 1381 2010/04