last modified：2026/08/20
Assistant Professor SAKO, Keisuke
Faculty, Affiliation
University Hospital
College and School Educational Field
Laboratory
Academic Background
Career
Harvard Medical School Brigham and Women's Hospital, Department of Medicine, Renal division(2021/04-2023/03)
(2012/04-2012/06)
(2013/04-2013/12)
(2019/04-2021/03)
(2018/04-2019/03)
(2016/04-2018/03)
(2015/04-2016/03)
(2014/04-2015/03)
(2012/07-2013/02)
(2024/08-)
Kanazawa University Hospital Nephrology and Laboratory Medicine(2023/04-2024/09)
(2014/01-2014/03)
(2013/03-2013/03)
Year & Month of Birth
Academic Society
Award
○Encouragement Award(2017/12)
○Encouragement Award(2017/12)
○Encouragement Award(2017/12)
○Encouragement Award(2017/12)
Specialities
、
Speciality Keywords
Research Themes
Books
Papers
- Vascular Endothelial Growth Factor Receptor 2-Targeted Therapy Suppresses the Progression of Alpha-Fetoprotein-Positive Hepatocellular Carcinoma After Combination Therapy With Anti-Programmed Death-Ligand 1 and Anti-Vascular Endothelial Growth Factor-A Antibodies. Gen Sugiyama,Kouki Nio,Hikari Okada,Akihiko Kida,Keisuke Sako,Yasunori Iwata,Hideo Takayama,Yutaro Kawakami,Tomoyoshi Chiba,Kazuki Nagai,Saiho Sugimoto,Masaki Nishitani,Tomoyuki Hayashi,Hajime Takatori,Tetsuro Shimakami,Masao Honda,Taro Yamashita Gastro hep advances 5 1 100778 2026
- Kidney lesions and risk of cardiovascular events in biopsy-proven diabetic kidney disease with type 2 diabetes. Miho Shimizu,Kengo Furuichi,Tadashi Toyama,Masayuki Yamanouchi,Daiki Hayashi,Akihiko Koshino,Keisuke Sako,Keisuke Horikoshi,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Megumi Oshima,Shiori Nakagawa,Shinji Kitajima,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Kiyoki Kitagawa,Mitsuhiro Yoshimura,Junichi Hoshino,Yoshifumi Ubara,Yasunori Iwata,Takashi Wada Clinical and experimental nephrology 2024/10/28
- CD45 + C1q + CCR8+ Cells as Emerging Indicators of Kidney Disease Severity and Progression Risk. Koichi Sato,Megumi Oshima,Norihiko Sakai,Yu Oshima,Daichi Kaikoi,Daiki Hayashi,Naoki Yamamoto,Takahiro Matsuno,Akihiko Koshino,Keisuke Sako,Keisuke Horikoshi,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Shiori Nakagawa,Shinji Kitajima,Tadashi Toyama,Akinori Hara,Miho Shimizu,Takashi Wada,Yasuhiko Yamamoto,Yasunori Iwata Nephrology (Carlton, Vic.) 30 9 e70126 2025/09
- d‐Alanine Hydrochloride and d‐Alanine Dipeptide Have Biological Activity and Promote Human Proximal Tubular Epithelial Cell Viability Keisuke Sako,Yohei Saito,Yusuke Nakade,Hoang Thuy Linh,Akihiko Koshino,Keisuke Horikoshi,Takahiro Yuasa,Akira Tamai,Shunsuke Tsuge,Taichiro Minami,Megumi Oshima,Ryo Nishioka,Kiyoaki Ito,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Miho Shimizu,Masashi Mita,Takashi Wada,Kyoko Nakagawa‐Goto,Yasunori Iwata Chemistry & Biodiversity 2026/01
- Fibroblast-specific palladin drives kidney fibrosis via MRTF-SRF signaling. Naoki Yamamoto,Norihiko Sakai,Yuta Yamamura,Daichi Kaikoi,Daiki Hayashi,Takahiro Matsuno,Akihiko Koshino,Keisuke Sako,Keisuke Horikoshi,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Megumi Oshima,Shiori Nakagawa,Shinji Kitajima,Akinori Hara,Miho Shimizu,Jumpei Terakawa,Shin-Ichi Horike,Takiko Daikoku,Atsushi Mizokami,Hiroko Ikeda,Moeno Kadoguchi,Hiroshi Arakawa,Sumio Ohtsuki,David Lagares,Takashi Wada,Yasunori Iwata The Journal of pathology 2025/10/24
- Interstitial palladin expression is associated with increased risk of end-stage kidney disease and death in patients with biopsy-proven diabetic kidney disease. Naoki Yamamoto,Norihiko Sakai,Daichi Kaikoi,Takahiro Matsuno,Akihiko Koshino,Keisuke Sako,Taku Kobayashi,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Yuta Yamamura,Megumi Oshima,Satoshi Hara,Kiyoaki Ito,Akinori Hara,Miho Shimizu,Takashi Wada,Yasunori Iwata Clinical and experimental nephrology 2026/03/26
- Autotaxin concentrations in peritoneal dialysis effluent reflect peritoneal function. Keisuke Horikoshi,Norihiko Sakai,Megumi Oshima,Hiroyuki Yamauchi,Megumi Ikeda,Kaho Hayashi,Hiroyoshi Yanagisawa,Fumitaka Yamamori,Sho Kajikawa,Daiki Hayashi,Akihiko Koshino,Keisuke Sako,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Shiori Nakagawa,Shinji Kitajima,Tadashi Toyama,Akinori Hara,Miho Shimizu,Satoshi Oota,Yoichi Ishida,Takashi Wada,Yasunori Iwata Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2024/09/26
- Antibiotics- and immunosuppressants-related AKI Kengo Furuichi,Keisuke Sako,Takashi Wada Acute Kidney Injury and Regenerative Medicine 99 2020/01/01
- Association between the recurrence period of acute kidney injury and mortality: a single-centre retrospective observational study in Japan Keisuke Sako,Kengo Furuichi,Yuta Yamamura,Megumi Oshima,Tadashi Toyama,Shuichi Kaneko,Takashi Wada BMJ Open 9 6 e023259 2019/06
- Rescue of fulminant Clostridioides difficile infection in a hemodialysis patient: a case report Hiroyoshi Yanagisawa,Megumi Oshima,Keisuke Sako,Yoshinori Takahashi,Toshiaki Tokumaru,Kaho Hayashi,Megumi Ikeda,Fumitaka Yamamori,Sho Kajikawa,Daiki Hayashi,Takahiro Yuasa,Keisuke Horikoshi,Shiori Nakagawa,Shinji Kitajima,Tadashi Toyama,Akinori Hara,Norihiko Sakai,Miho Shimizu,Takumi Taniguchi,Takashi Wada,Yasunori Iwata RENAL REPLACEMENT THERAPY 11 1 2025/07/29
- Correction: Kidney lesions and risk of cardiovascular events in biopsy-proven diabetic kidney disease with type 2 diabetes. Miho Shimizu,Kengo Furuichi,Tadashi Toyama,Masayuki Yamanouchi,Daiki Hayashi,Akihiko Koshino,Keisuke Sako,Keisuke Horikoshi,Takahiro Yuasa,Akira Tamai,Taichiro Minami,Megumi Oshima,Shiori Nakagawa,Shinji Kitajima,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Kiyoki Kitagawa,Mitsuhiro Yoshimura,Junichi Hoshino,Yoshifumi Ubara,Yasunori Iwata,Takashi Wada Clinical and experimental nephrology 29 3 387 2025/03
- Effects of risperidone on amino acid metabolism, glucose, and kidney function in healthy adults: A pilot randomized controlled trial. Megumi Oshima,Tadashi Toyama,Yusuke Nakade,Sakae Miyagi,Hisayuki Ogura,Shiori Nakagawa,Takahiro Yuasa,Akihiko Koshino,Keisuke Horikoshi,Taichiro Minami,Keisuke Sako,Shunsuke Tsuge,Akira Tamai,Ryo Nishioka,Taro Miyagawa,Kiyoaki Ito,Shinji Kitajima,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Miho Shimizu,Toshiaki Tokumaru,Makoto Tsubomoto,Mitsuru Kikuchi,Masashi Kinoshita,Mitsutoshi Nakada,Masashi Mita,Yasunori Iwata,Takashi Wada PloS one 20 12 e0324222 2025
- Protective Role of MAVS Signaling for Murine Lipopolysaccharide-Induced Acute Kidney Injury. Trang Anh Thi Tran,Yasunori Iwata,Linh Thuy Hoang,Shinji Kitajima,Shiori Yoneda-Nakagawa,Megumi Oshima,Norihiko Sakai,Tadashi Toyama,Yuta Yamamura,Hiroka Yamazaki,Akinori Hara,Miho Shimizu,Keisuke Sako,Taichiro Minami,Takahiro Yuasa,Keisuke Horikoshi,Daiki Hayashi,Sho Kajikawa,Takashi Wada ImmunoHorizons 8 1 1 2024/01/01
- Cyclin-dependent kinase 4-related tubular epithelial cell proliferation is regulated by Paired box gene 2 in kidney ischemia-reperfusion injury. Keisuke Sako,Kengo Furuichi,Shohei Makiishi,Yuta Yamamura,Toshiya Okumura,Hong Thu Le,Shinji Kitajima,Tadashi Toyama,Akinori Hara,Yasunori Iwata,Norihiko Sakai,Miho Shimizu,Fumio Niimura,Taiji Matsusaka,Shuichi Kaneko,Takashi Wada Kidney international 102 1 45 2022/04/25
- KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney. Yutaro Mori,Corby Fink,Takaharu Ichimura,Keisuke Sako,Makiko Mori,Nathan N Lee,Philipp Aschauer,Krishna M Padmanabha Das,SoonGweon Hong,Minsun Song,Robert F Padera,Astrid Weins,Luke P Lee,Mahmoud L Nasr,Gregory A Dekaban,Jimmy D Dikeakos,Joseph V Bonventre medRxiv : the preprint server for health sciences 2022/01/11
- Identification of candidate PAX2-regulated genes implicated in human kidney development Yuta Yamamura,Kengo Furuichi,Yasuhiro Murakawa,Shigeki Hirabayashi,Masahito Yoshihara,Keisuke Sako,Shinji Kitajima,Tadashi Toyama,Yasunori Iwata,Norihiko Sakai,Kazuyoshi Hosomichi,Philip M. Murphy,Atsushi Tajima,Keisuke Okita,Kenji Osafune,Shuichi Kaneko,Takashi Wada Scientific Reports 11 1 9123 2021/04
- Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice Shohei Makiishi,Kengo Furuichi,Yuta Yamamura,Keisuke Sako,Yasuyuki Shinozaki,Tadashi Toyama,Shinji Kitajima,Yasunori Iwata,Norihiko Sakai,Miho Shimizu,Tomoko Hirose-Sugiura,Shuichi Kaneko,Yukio Kato,Takashi Wada Scientific Reports 11 1 9093 2021/04
- d-Alanine Supplementation for Chronic Kidney Disease: A Study Protocol for a Pilot Randomized Controlled Trial. Megumi Oshima,Tadashi Toyama,Yusuke Nakade,Goro Sakurai,Takahiro Yuasa,Akihiko Koshino,Keisuke Horikoshi,Taichiro Minami,Keisuke Sako,Shiori Nakagawa,Kiyoaki Ito,Shinji Kitajima,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Miho Shimizu,Toshiaki Tokumaru,Masashi Mita,Yasunori Iwata,Takashi Wada Chemistry & biodiversity 22 11 e00746 2025/11
- Identification of circulating microbial DNA and its association with kidney function in patients with diabetic kidney disease Hoang Thuy Linh,Megumi Oshima,Keisuke Sako,Masahiro Konishi,Daiki Hayashi,Hajime Sanada,Takahiro Yuasa,Akihiko Koshino,Keisuke Horikoshi,Taichiro Minami,Shunsuke Tsuge,Akira Tamai,Shiori Nakagawa,Ryo Nishioka,Takeshi Zoshima,Kiyoaki Ito,Ichiro Mizushima,Tadashi Toyama,Norihiko Sakai,Shinji Kitajima,Miho Shimizu,Takashi Wada,Yasunori Iwata Nephrology 2024/10/23
- Effects of d-alanine Intake on Amino Acid Metabolism and Kidney Function in Healthy Adults: A Multicenter, Randomized Pilot Study. Megumi Oshima,Tadashi Toyama,Tatsuhiko Toyama,Yusuke Nakade,Toshiaki Tokumaru,Keisuke Sako,Sho Kajikawa,Daiki Hayashi,Hajime Sanada,Takahiro Yuasa,Akihiko Koshino,Keisuke Horikoshi,Taichiro Minami,Shunsuke Tsuge,Akira Tamai,Shiori Nakagawa,Ryo Nishioka,Takeshi Zoshima,Kiyoaki Ito,Shinji Kitajima,Ichiro Mizushima,Akinori Hara,Norihiko Sakai,Miho Shimizu,Masashi Mita,Yasunori Iwata,Takashi Wada Current developments in nutrition 8 7 103787 2024/07