Specialities

Laboratory animal science、Pathological Model Knockout mice Glycosyltransferase

Speciality Keywords

Pathological Model,Knockout mice,Glycosyltransferase,

Research Themes

Books

Papers

• 　Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow　Soichiro Takagaki, Rieko Yamashita, Noriyoshi Hashimoto, Kazushi Sugihara, Kanako Kanari, Keisuke Tabata, Toshikazu Nishie, Shogo Oka, Masanori Miyanishi, Chie Naruse, and Masahide Asano　Sientific Reports　9　7133　2019/05/09
• 　Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome　PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME　106　2　468-473　2009/01
• 　Development of immunoglobulin A nephropathy- like disease in beta-1,4-galactosyltransferase-I-deficient mice　Nishie T, Miyaishi O, Azuma H, Kameyama A, Naruse C, Hashimoto N, Yokoyama H, Narimatsu H, Wada T, Asano M.　AMERICAN JOURNAL OF PATHOLOGY　170　2　447-456　2007/02
• 　Development of IgA nephropathy-like disease with high serum IgA levels and increased proportion of polymeric IgA in Beta-1,4-galactosyltransferase-deficient mice　CONTRIBUTIONS TO NEPHROLOGY　157　125-128　2007/06
• 　RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin　DIABETES　55　9　2510-2522　2006/09

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Conference Presentations

• Development of new albino inbred strain mice for embryo-transfer recipient(2018/05/16)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「骨髄幹細胞の新規ホーミング分子の同定と糖鎖修飾による効率的骨髄移植法の開発」(2011-2013)　
○「血球貪食症候を主徴とするリソソーム病の新規病態モデルの確立」(2009-2011)　
○「血球貪食症候を自然発症する新規動物モデルの開発と発症機構の解析」(2006-2008)　
○「遺伝子改変による癌特異糖鎖抗原機能解析のための基幹糖鎖構造転換マウスモデルの確立」(2003-2004)　
○「カルニチン欠乏症（JVS）マウスの病態発生に及ぼす環境ストレスの影響」(1998-)　
○「カルニチン欠乏症(JVS)マウスの病態発生に及ぼす環境ストレスの影響」(1997-)　
○「胚移植レシピエントのための新規アルビノ近交系マウスの開発」(2018-2020)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Laboratory animal science and stem cell biology(2018)
○Laboratory animal science and stem cell biology(2017)
○Laboratory animal science and stem cell biology(2016)

Classes (Graduate Schools)

○Advanced Transgenic Animal Science(2017)
○Mouse Embryo Manipulation Basic Course(2017)
○Seminar on Advanced Medical Science(2017)
○Advanced Transgenic Animal Science(2017)
○Seminar on Animal Experimentation(2017)
○Seminar on Animal Experimentation(2016)
○Introduction to Basic Medical Science(2016)