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Researcher Information

last modified:2024/09/25

Associate Professor MUKAI, Kanae

Laboratory Website

Faculty, Affiliation

Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Health Sciences, Graduate School of Medical Science
Department of Nursing,School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Academic Background

Career

School of Health Sciences, College of Medical, pharmaceutical and Health Sciences, Kanazawa University(2020/03/01-)
School of Health Sciences, College of Medical, pharmaceutical and Health Sciences, Kanazawa University(2015/03/24-2020/02/29)
Hokuriku Gakuin Junior College(2012/04/01-2014/09/30)

Year & Month of Birth

Academic Society












Award







Specialities

Speciality Keywords

estrogen, cutaneous wound healing, skin care, diabetes mellitus, aging

Research Themes

Books

Papers

  •  Topical estrogen application promotes cutaneous wound healing in db/db female mice with type 2 diabetes Kanae Mukai, Shin-ichi Horike, Makiko Meguro-Horike, Yukari Nakajima, Arya Iswara, Toshio Nakatani PLoS One 17 3 e0264572 2022
  •  Oral Microbiome Changes Associated with the Menstrual Cycle in Healthy Young Adult Females Ayaka Yamazaki, Kohei Ogura, Kana Minami, Kazuhiro Ogai, Tomomi Horiguchi, Shigefumi Okamoto, Kanae Mukai Frontiers in Cellular and Infection Microbiology, section Microbiome in Health and Disease 2023/03/31
  •  Effects of skin moisturizer on the skin barrier dysfunction model: An evaluation of the heel via tape-stripping in healthy, young adults Kanae Mukai, Kazuhiro Ogai, Sayaka Ishino, Shiona Kamijo, Fuka Kurata, Ayano Sugitani, Wakaba Tachibana, Ami Nishiyama, Akira Fukuyama, Kotono Wada, Mayuko Yamaguchi, Junko Sugama Journal of Tissue Viability in press 2021
  •  Wound healing in db/db mice with type 2 diabetes using non-contact exposure with an argon non-thermal atmospheric pressure plasma jet device Arya Iswara, Kenta Tanaka, Tatsuo Ishijima, Yukari Nakajima, Kanae Mukai, Yasunori Tanaka, Yusuke Nakano, Junko Sugama, Makoto Oe, Mayumi Okuwa, Toshio Nakatani PLoS One 17 10 e0275602 2022
  •  Factors affecting superficial vein visibility at the upper limb in healthy young adults: A cross-sectional observational study Kanae Mukai, Taiga Fujii, Yukari Nakajima, Asami Ishida, Moeka Kato, Mao Takahashi, Mihiro Tsuda, Nanami Hashiba, Namiko Mori, Ayaka Yamanaka, Toshio Nakatani The Journal of Vascular Access [Online ahead of print] 2020

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  •  Safety of Venipuncture Sites at the Cubital Fossa as Assessed by Ultrasonography Mukai K, Nakajima Y, Nakano T, Okuhira M, Kasashima A, Hayashi R, Yamashita M, Urai T, Nakatani T Journal of Patient Safety 16 1 98-105 2020
  •  Distinct skin microbiome and skin physiological functions between bedridden older patients and healthy people: A single-center study in Japan Satoshi Nagase, Kazuhiro Ogai, Tamae Urai, Kana Shibata, Emi Matsubara, Kanae Mukai, Miki Matsue, Yumiko Mori, Miku Aoki, Defa Arisandi, Junko Sugama, Shigefumi Okamoto Front Med (Lausanne) 7 101 2020
  •  A Comparison of Techniques for Collecting Skin Microbiome Samples: Swabbing versus Tape-Stripping Kazuhiro Ogai, Satoshi Nagase, Kanae Mukai, Terumi Iuchi, Yumiko Mori, Miki Matsue, Kayo Sugitani, Junko Sugama, Shigefumi Okamoto Frontiers in Microbiology 2 9 2362 2018/10/02
  •  Japanese clinical practice guidelines for aspiration and pharyngeal residual assessment during eating and swallowing for nursing care Junko Sugama, Miyuki Ishibasi, Erika Ota, Yayoi Kamakura, Eiichi Saitoh, Hiromi Sanada, Takeo Nakayama, Takeshi Nomura, Masako Yamada, Gojiro Nakagami, Naoko Sato, Seiko Shibata, Takashi Hase, Junko Fukada, Tatsuto Miki, Mikiko Arita, Tamae Urai, Yohei Okawa, Aya Kitamura, Misako Dai, Toshiaki Takahashi, Nao Tamai, Itoko Tobita, Hiroshi Noguchi, Masaru Matsumoto, Yuka Miura, Kanae Mukai, Yuko Mugita, Mikako Yoshida, Masako Kurachi, Takako Shirasaka, Yukiko Yamane Japan Journal of Nursing Science e12496 2022
  •  Association of Skin Microbiome with the Onset and Recurrence of Pressure Injury in Bedridden Elderly People Shigefumi Okamoto,Kazuhiro Ogai,Kanae Mukai Junko Sugama Microorganisms 9 8 1603 2021
  •  Diagnostic accuracy of ultrasound examination in detecting aspiration and pharyngeal residue in patients with dysphagia: A systematic review and meta-analysis Miura Y, Tamai N, Kitamura A, Yoshida M, Takahashi T, Mugita Y, Tobita I, Arita M, Urai T, Dai M, Noguchi H, Matsumoto M, Mukai K, Nakagami G, Ota E, Sugama J, Sanada H Japan Journal of Nursing Science in press 2020
  •  Novel Hyaluronate Lyase Involved in Pathogenicity of Streptococcus dysgalactiae subsp. Equisimilis Van An Nguyen, Kohei Ogura, Miki Matsue, Norihiko Takemoto, Kanae Mukai, Yukari Nakajima, Thuy Linh Hoang, Yasunori Iwata, Norihiko Sakai, Takashi Wada, Wataru Hashimoto, Shigefumi Okamoto, Hiroshi Ichimura Frontiers Microbiology 11 552418 2020
  •  Anatomically safe sites for intramuscular injections: a cross-sectional study on young adults and cadavers with a focus on the thigh Nakajima Y, Fujii T, Mukai K, Ishida A, Kato M, Takahashi M, Tsuda M, Hashiba N, Mori N, Yamanaka A, Ozaki N, Nakatani T Human Vaccines & Immunotherapeutics 16 1 189-196 2020
  •  Pre-collecting lymphatic vessels form detours following obstruction of lymphatic flow and function as collecting lymphatic vessels Kimi Asano,Yukari Nakajima,Kanae Mukai,Tamae Urai,Mayumi Okuwa,Junko Sugama,Chizuko Konya,Toshio Nakatani Plos One 15 1 e0227814 2020
  •  Longitudinal investigation of propionibacterium acnes burden and skin physiological function during menstruation in healthy women Kanae Mukai, Kazuhiro Ogai, Masato Kobayashi, Terumi Ueda, Yukari Nakajima, Toshio Nakatani Structure and Function 18 1 20-30 2019
  •  Near-infrared fluorescence imaging directly visualizes lymphatic drainage pathways and connections between superficial and deep lymphatic systems in the mouse hindlimb Nakajima Yukari, Asano Kimi, Mukai Kanae, Urai Tamae, Okuwa Mayumi, Sugama Junko, Nakatani Toshio  Scientific Reports 8 1 7078 2018
  •  Efficacy of honeydew honey and blossom honey on full-thickness wound healing in mice Sawazaki T*, Nakajima Y*, Urai T, Mukai K, Ohta M, Kato I, Kawaguchi A, Kinoshita Y, Kumagai Y, Sakashita A, Yamazaki A, Nakatani T WOUNDS 30 7 197-204 2018
  •  Non-invasive longitudinal monitoring of angiogenesis in a murine full-thickness cutaneous wound healing model using high-resolution three-dimensional ultrasound imaging Kanae Mukai, Wenjing Zhu, Yukari Nakajima, Masato Kobayashi, Toshio Nakatani Skin Research and Technology 23 4 581-587 2017
  •  Does Obesity without Hyperglycemia Delay Wound Healing in an Obese Mouse Model Induced by a High-Fat Diet?  Urai T, Nakajima Y, Mukai K, Asano K, Okuwa M, Sugama J, Nakatani T Health 9 12 1660-1679 2017
  •  Establishing a new appropriate intramuscular injection site in the deltoid muscle Yukari Nakajima, Kanae Mukai, Kana Takaoka, Toshiko Hirose, Keiko Morishita, Takuya Yamamoto, Yuka Yoshida, Tamae Urai, Toshio Nakatani Human Vaccines & Immunotherapeutics 12 1-7 2017
  •  Lymph drainage during wound healing in a hindlimb mouse model Emi Komatsu, Yukari Nakajima, Kanae Mukai, Tamae Urai, Kimi Asano, Mayumi Okuwa, Junko Sugama, Toshio Nakatani Lymphatic Research and Biology 15 1 32-38 2017
  •  Effectiveness of Changing the Application of Japanese Honey to a Hydrocolloid Dressing in Between the Inflammatory and Proliferative Phases on Cutaneous Wound Healing in Male Mice  Kanae Mukai, Emi Komatsu, Misa Yamanishi, Misako Hutakuchi, Kayo Kanzaka, Yuka Uno, Shizuka Yamazaki, Shizuka Kato, Tomomi Yamamoto, Mayumi Hattori, Yukari Nakajima, Tamae Urai, Kimi Asano, Naoko Murakado, Mayumi Okuwa, Toshio Nakatani WOUNDS 29 1 1-9 2017
  •  17β-Estradiol administration promotes delayed cutaneous wound healing in 40-week ovariectomised female mice  Kanae Mukai, Yukari Nakajima, Tamae Urai, Emi Komatsu, Nasruddin, Junko Sugama, Toshio Nakatani International Wound Journal 13 5 636-644 2016
  •  The effect of 17β-estradiol on cutaneous wound healing in protein-malnourished ovariectomized female mouse model (doi:10.1371/journal.pone.0115564) Kanae Mukai, Emi Komatsu, Yukari Nakajima, Tamae Urai, Nasruddin, Junko Sugama, Toshio Nakatani PLOS ONE 9 12 e115564 2014/12
  •  A simple technique to improve contractile effect of cold plasma jet on acute wound of mouse by dropping water Nasruddin, Yukari Nakajima, Kanae Mukai, Emi Komatsu, Heni Setyowati Esti Rahayu, Muhammad Nur, Tatsuo Ishijima, Hiroshi Enomoto, Yoshihiko Uesugi, Junko Sugama, Toshio Nakatani Plasma Processes and Polymers 12 10 1128-1138 2015/10
  •  Evaluation of effects of topical estradiol benzoate application on cutaneous wound healing in ovariectomized female mice  Kanae Mukai, Tamae Urai, Kimi Asano, Yukari Nakajima, Toshio Nakatani PLOS ONE  in press 2016
  •  The relationship between cutaneous wounds made on obese mice or those with decreased body weight and serum leptin level Tamae Urai, Haryanto, Kanae Mukai, Tatsuhiko Matsushita, Kimi Asano, Yukari Nakajima, Mayumi Okuwa, Junko Sugama, Toshio Nakatani  Health 8 11 1015-1028 2016/08
  •  Anatomical investigation of position of crossing of superficial branch of radial nerve and cephalic vein and its frequency Kanae Mukai, Emi Komatsu, Tamae Urai, Yukari Nakajima, Kimi Asano, Noriyuki Ozaki, Toshio Nakatani Structure and Function 14 1 3-10 2015/08
  •  Evaluation of the effects of a combination of Japanese honey and hydrocolloid dressing on cutaneous wound healing in male mice Kanae Mukai, Miki Koike, Saki Nakamura, Fumika Katagiri, Saki Nojiri, Yuki Yamada, Eri Miyajima, Mayuko Matsumoto, Emi Komatsu, Yukari Nakajima, Tamae Urai, Naoko Murakado, Toshio Nakatani Evidence-Based Complementary and Alternative Medicine vol. 2015 Article ID 910605 9 pages 2015/04
  •  The effect of 17β-estradiol administration on cutaneous wound healing in 24-week ovariectomized female mice Kanae Mukai, Yukari Nakajima, Tamae Urai, Emi Komatsu, Kana Takata, Yuriko Miyasaka, Nasruddin, Junko Sugama, Toshio Nakatani Journal of Hormones Article ID 234632 8 pages 2014/01
  •  Comparison of the cutaneous wound healing of ovariectomized mouse at 12 weeks with that of SHAM and estrogen-administered mice Kanae Mukai, Yuriko Miyasaka, Kana Takata, Tamae Urai, Yukari Nakajima, Emi Komatsu, Junko Sugama, Toshio Nakatani Journal of Hormones Article ID 484258 6 pages 2014/07
  •  Cold plasma on full-thickness cutaneous wound accelerates healing through promoting inflammation, re-epithelialization and wound contraction Nasruddin, Yukari Nakajima, Kanae Mukai, Heni Setyowati Esti Rahayu, Muhammad Nur,Tatsuo Ishijima, Hiroshi Enomoto, Yoshihiko Uesugi, Junko Sugama, Toshio Nakatani Clinical Plasma medicine 2 1 28-35 2014/07
  •  Evaluation of the effects of honey on acute-phase deep burn wounds Yukari Nakajima, Kanae Mukai, Nasruddin Nasruddin, Emi Komatsu, Terumi Iuchi, Yukie Kitayama, Junko Sugama, Toshio Nakatani Evidence-Based Complementary and Alternative Medicine Article ID 784959 20 pages 2013/08
  •  Effects of three types of Japanese honey on full-thickness wound in mice Evidence-Based Complementary and Alternative Medicine Article ID 504537 11 pages 2012/10
  •  Is estrogen effective for full-thickness cutaneous wound healing in young male mice?  WOUNDS 25 10 278-286 2013/10
  •  Effectiveness of Indonesian honey towards acceleration of cutaneous wound healing: an experimental study in mice Haryanto, Tamae Urai, Kanae Mukai, Suriadi, Junko Sugama, Toshio Nakatani WOUNDS 24 4 110-119 2012/04
  •  The effect of isoflavone-daidzein oral medication on cutaneous wound healing in female ovariectomized mice Kanae Mukai, Mari Nagasawa, Eri Nakamura, Natsuki Nishida, Ayaka Hori, Yukari Yagi, Aya Yamagishi, Ai Watanabe, Tamae Urai, Kana Takada, Yuriko Hara, Yukari Nakajima, Mayumi Okuwa, Miho Shogenzi, Toshio Nakatani Structure and Function 10 2 96-102 2012/03
  •  Optimal nocturnal care for pressure injury prevention in the care environment: A scoping review Mao Kunimitsu, Kanae Mukai, Ami Tagawa; Hikari Takihira; Yuka Hiromitsu; Ayari Yamaguchi; Saeka Shiraki; Yukari Nakajima, Oe Makoto Journal of Tissue Viability Online ahead of print 2024/08
  •  Relationship between topical treatment and pH in the healing process of diabetic foot ulcer: a scoping review  Sukarni, Muhammad Aminuddin, Kanae Mukai, Makoto Oe  Journal of Japanese Society of Wound, Ostomy and Continence Management  28 1 29-37 2024/05
  •  Education of healthcare professionals for the prevention and treatment of diabetic foot ulcers: A scoping review Muhammad Aminuddin, Sukarni, Kanae Mukai, Makoto Oe  Journal of Japanese Society of Wound, Ostomy and Continence Management 28 1 11-24 2024/03
  •  Difference in clinicopathological characteristics between lipohypertrophy and localized insulin-derived amyloidosis: A scoping review Kanae Mukai, Hiromasa Tanno, Junko Sugama, Toshihiko Yanagita, Emi Kanno Chronic Diseases and Translational Medicine 2023/11
  •  Effects of inhibition of lymphangiogenesis by the vascular endothelial growth factor receptor 3 (VEGFR-3) inhibitor, MAZ51 on full thickness wounds in mice Kana Takada, Yukari Nakajima, Tamae Urai, Kanae Mukai, Kimi Asano, Mayumi Okuwa, Junko Sugama, Toshio Nakatani Veins and Lymphatics 10 1 2021

Conference Presentations

  • Evaluation of the effect of estradiol benzoate on cutanoues wound healing in ovariectomized female mice. Focus on the imflammatory response.(conference:WUWHS2016)(2016/09)
  • The effect of estrogen endermic medication on cutaneous wound healing in aged ovariectomized female mice(conference:4th Congress of the World Union of Wound Healing Societies)(2012/09)
  • 17β-estradiol promotes cutaneous wound healing in 24-week ovariectomized female mice by modulating wound inflammation and promoting wound contraction(conference:XXIII International Symposium on Morphological Sciences)(2013/09)
  • Establishment of a skin barrier dysfunction model for the heel using tape stripping in young adults(2020/12/12)
  • Estrogen promotes cutaneous wound healing in type-2 diabetic db/db female mice(conference:WUWHS2020(WUWHS2020 Congress on the WUWHS.online web platform))(2020)

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  • The effect of isoflavone on wound healing of full thickness skin defect in ovariectomized mice given feed containing isoflavone(2011/03)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「リンパ浮腫に続発するレンサ球菌での蜂窩織炎発症機序とその予防・緩和ケア対策」(2021-2024) 
○「糖尿病性潰瘍のケア方法創出に向けた基礎研究:エストロゲン作用の治癒メカニズム解明」(2021-2024) 
○「異分野融合研究による女性ホルモンの変動と口腔マイクロバイオームの関連の解明」(2020-2022) 
○「リンパ管のin vitroモデル構築とリンパ浮腫治療法開発の基礎研究」(2020-2024) 
○「リンパ浮腫に対する培養リンパ管移植の効果と瘢痕組織のリンパ管再生阻害の基礎研究」(2018-2020) 
○「2型糖尿病モデルマウス皮膚創傷へのエストロゲン創部塗布効果の網羅的解明」(2018-2020) 
○「マウスを用いたリンパ浮腫発生機序から浮腫軽減や線維化を防止する効果的なケアの開発」(2016-2018) 
○「糖尿病性潰瘍の治癒促進に向けたエストロゲンによる血管新生促進作用の解明」(2016-) 
○「皮膚創傷治癒促進に有効なケア開発の基礎ー17βエストラジオール投与方法の選定ー」 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Introduction to Infection Control(2022)
○Fundamental Nursing: Clinical Practice(2022)
○Human Physiology(2022)
○Study Abroad(2022)
○Standard Nursing: Skills Laboratory(2022)
○Introduction of Clinical Nursing(2022)
○Health Assessment: Skills Laboratory(2022)
○Fundamental Nursing: Clinical Practice(2022)
○Basic Physiology(2022)
○Concept of Nursing Research(2022)
○Conceptual Basis of Nursing Practice(2022)
○Basic Anatomy(2022)
○Introduction to Infection Control(2021)
○Standard Nursing: Skills Laboratory(2021)
○Basic Anatomy(2021)
○Conceptual Basis of Nursing Practice(2021)
○Concept of Nursing Research(2021)
○Introduction to Nursing: Laboratory Practice(2021)
○Fundamental Nursing: Clinical Practice(2021)
○Introduction of Clinical Nursing(2021)
○Nursing Research: Practice(2020)
○Advanced Nursing: Clinical Practice(2020)
○Fundamental Nursing: Clinical Practice(2020)
○Health Assessment: Skills Laboratory(2020)
○Standard Nursing: Skills Laboratory(2020)
○Concept of Nursing Research(2020)
○Conceptual Basis of Nursing Practice(2020)
○Introduction to Infection Control(2020)
○Introduction to Region-studies(2020)
○Freshman Seminar I(2020)
○Presentation and Debate (Freshman Seminar II)(2020)
○Introduction to Infection Control(2019)
○Fundamental Nursing: Clinical Practice(2019)
○Standard Nursing: Skills Laboratory(2019)
○Advanced Nursing: Clinical Practice(2019)
○Introduction to Nursing: Laboratory Practice(2019)
○Health Assessment: Skills Laboratory(2019)
○Nursing Research: Practice(2019)
○Nursing Research: Practice(2018)
○Fundamental Nursing: Clinical Practice(2018)
○Introduction to Infection Control(2018)
○Standard Nursing: Skills Laboratory(2018)
○Health Assessment: Skills Laboratory(2018)
○Nursing Research: Practice(2017)
○Fundamental Nursing: Clinical Practice(2017)
○Standard Nursing: Skills Laboratory(2017)
○Fundamental Nursing: Clinical Practice(2017)
○Health Assessment: Skills Laboratory(2017)

Classes (Graduate Schools)

○Chronic Care & Wound Management: Seminar(2022)
○Chronic Care/Wound Management: Lecture(2022)
○Wound Management: Seminar(2022)
○Wound Management: Lecture(2022)
○Chronic Care Nursing & Wound Management: Research(2022)
○Wound Management: Seminar(2020)
○Wound Management: Lecture(2020)

International Project

International Students

Lecture themes

Others (Social Activities)

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