last modified：2026/08/20
Assistant Professor FUTAGI, Yuya
Faculty, Affiliation
University Hospital
College and School Educational Field
Laboratory
Academic Background
Career
(2026/07-)
(2026/07-)
(2024/09-2024/10)
Kanazawa University Hospital, Department of Hospital Pharmacy(2020/04-)
Hokkaido University Graduate School of Life Science(2017/04-2020/03)
Hokkaido University Graduate School of Life Science(2016/04-2017/03)
Year & Month of Birth
Academic Society
THE PHARMACEUTICAL SOCIETY OF JAPAN
The Japanese Society of Pharmaceutical Health Care and Sciences
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
Award
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
Specialities
biomembrane transport、
Speciality Keywords
Research Themes
Books
Papers
- Impact of antithymocyte globulin on blood cyclosporin A levels in aplastic anemia patients Yuya Futagi,Yukio Suga,Tsutomu Shimada,Yoshimichi Sai Annals of Hematology 102 2 463 2022/11/26
- Ceftriaxone-induced encephalopathy in a patient with a solitary kidney. Yuya Futagi,Yuriko Ito,Junya Nakade,Arimi Fujita,Tsutomu Shimada,Misaki Yoshida,Yoshinori Takahashi,Mitsuhiro Kawano,Takumi Taniguchi,Yoshimichi Sai International journal of infectious diseases 122 1 722 2022/07/14
- Molecular determinants of substrate selectivity in human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4) Yuya Futagi 2020/03
- Molecular characterization of the orphan transporter SLC16A9, an extracellular pH- and Na+-sensitive creatine transporter. Yuya Futagi,Katsuya Narumi,Ayako Furugen,Masaki Kobayashi,Ken Iseki Biochemical and biophysical research communications 522 2 539 2020/02/05
- Extracellular lysine 38 plays a crucial role in pH-dependent transport via human monocarboxylate transporter 1. Atsushi Yamaguchi,Yuya Futagi,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki Biochimica et biophysica acta. Biomembranes 1862 2 183068 2020/02/01
- Homology modeling and site-directed mutagenesis identify amino acid residues underlying the substrate selection mechanism of human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4). Yuya Futagi,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki Cellular and molecular life sciences : CMLS 76 24 4905 2019/12
- Identification of a selective inhibitor of human monocarboxylate transporter 4. Yuya Futagi,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki Biochemical and biophysical research communications 495 1 427 2018/01/01
- Involvement of monocarboxylate transporter 1 (SLC16A1) in the uptake of l-lactate in human astrocytes. Masaya Ideno,Masaki Kobayashi,Shotaro Sasaki,Yuya Futagi,Katsuya Narumi,Ayako Furugen,Ken Iseki Life sciences 192 110 2018/01/01
- The flexible cytoplasmic loop 3 contributes to the substrate affinity of human monocarboxylate transporters Yuya Futagi,Shotaro Sasaki,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1859 10 1790 2017/10
- Interaction of atorvastatin with the human glial transporter SLC16A1 Shotaro Sasaki,Yuya Futagi,Masaya Ideno,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki EUROPEAN JOURNAL OF PHARMACOLOGY 788 248 2016/10
- Effect of diclofenac on SLC16A3/MCT4 by the Caco-2 cell line Shotaro Sasaki,Yuya Futagi,Masaya Ideno,Masaki Kobayashi,Katsuya Narumi,Ayako Furugen,Ken Iseki DRUG METABOLISM AND PHARMACOKINETICS 31 3 218 2016/06
- Influence of high glucose state on bromopyruvate-induced cytotoxity by human colon cancer cell lines Masaya Ideno,Shotaro Sasaki,Masaki Kobayashi,Yuya Futagi,Katsuya Narumi,Ken Iseki DRUG METABOLISM AND PHARMACOKINETICS 31 1 67 2016/02
- Involvement of Histidine Residue His382 in pH Regulation of MCT4 Activity Shotaro Sasaki,Masaki Kobayashi,Yuya Futagi,Jiro Ogura,Hiroaki Yamaguchi,Ken Iseki PLOS ONE 10 4 e0122738 2015/04
- Functional Characterization of 5-Oxoproline Transport via SLC16A1/MCT1 Shotaro Sasaki,Yuya Futagi,Masaki Kobayashi,Jiro Ogura,Ken Iseki JOURNAL OF BIOLOGICAL CHEMISTRY 290 4 2303 2015/01
- Crucial Residue Involved in L-Lactate Recognition by Human Monocarboxylate Transporter 4 (hMCT4) Shotaro Sasaki,Masaki Kobayashi,Yuya Futagi,Jiro Ogura,Hiroaki Yamaguchi,Natsuko Takahashi,Ken Iseki PLOS ONE 8 7 e67690 2013/07
Conference Presentations
- Career and research initiatives of pharmacists supporting community medicine and pharmaceutical education(2025/03)
- The role of M69 and F367 in the substrate specificity of hMCT1(2020/03)
Others
- Ceftriaxone-induced encephalopathy in a patient with a solitary kidney 二木悠哉,伊藤ゆり子,中出順也,中出順也,藤田有美,藤田有美,嶋田努,嶋田努,吉田美咲,高橋芳徳,高橋芳徳,川野充弘,谷口巧,崔吉道,崔吉道 日本薬学会年会要旨集(Web) 143rd 2023
- hMCT1,4の基質選択性に関わるアミノ酸残基の探索 二木悠哉,二木悠哉,古堅彩子,鳴海克哉,小林正紀,井関健,井関健 日本薬学会年会要旨集(CD-ROM) 138th 3 ROMBUNNO.27U‐am06S 2018/03
- hMCT1,4を介した基質輸送における細胞内ループの役割 二木悠哉,佐々木将太郎,小林正紀,井関健 日本薬学会年会要旨集(CD-ROM) 136th 3 ROMBUNNO.27Q‐PM01S 2016/03
- 大豆イソフラボンによるモノカルボン酸輸送担体の阻害効果を利用したがん細胞増殖の回避戦略 小林正紀,佐々木将太郎,二木悠哉,関口穂乃佳,鳴海克哉,高橋夏子,井関健,井関健 日本未病システム学会学術総会抄録集 22nd 122 2015/09/10
- 高グルコース環境培養下での大腸癌細胞株のハロゲン置換有機酸感受性の変化 井手野将也,佐々木将太郎,小林正紀,二木悠哉,井関健 トランスポーター研究会年会抄録集 10th 39 2015/06/20
- SLC16A1発現抑制による細胞内グルタチオン量の変化 佐々木将太郎,木村有希,小林正紀,二木悠哉,井関健 日本薬学会年会要旨集(CD-ROM) 135th 3 ROMBUNNO.26U-PM04 2015/03
- SLC16A1を介したプロチレリン代謝物輸送への遺伝子多型(rs1049434)の影響 佐々木将太郎,二木悠哉,小林正紀,井関健 日本薬剤学会年会講演要旨集(Web) 29th 20E1-5 (WEB ONLY) 2014/05
- hMCT1を介したコール酸輸送機構の解析 二木悠哉,佐々木将太郎,小林正紀,井関健 日本薬学会年会要旨集(CD-ROM) 134th 4 ROMBUNNO.29V-PM12S 2014/03
- 担体介在非飽和性グルタミン輸送の評価 佐々木将太郎,小林正紀,二木悠哉,小西徹,井関健 生体膜と薬物の相互作用シンポジウム講演要旨集 35th 82 2013/11/21
- モノカルボン酸輸送担体hMCT1,4の機能解析 佐々木将太郎,小林正紀,二木悠哉,井関健 トランスポーター研究会年会抄録集 8th 81 2013