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Researcher Information

last modified:2018/04/13

Professor TANAKA Shigeo

Mail Laboratory Website

Faculty, Affiliation

Faculty of Frontier Engineering,Institute of Science and Engineering

College and School Educational Field


Division of Innovative Technology and Science, Graduate School of Natural Science and Technology
School of Mechanical Engineering, College of Science and Engineering

Laboratory

Bioengineering Laboratory TEL:076-264-6466 FAX:076-264-6466

Academic Background

【Academic background(Doctoral/Master's Degree)】
Niigata University Master 199108 Completed
Niigata University Doctor 199405 Completed
【Academic background(Bachelor's Degree)】
Niigata University 198903

Career

Japan Advanced Institute of Science and Technology School of Materials Science Research Associate(1994/04/01-1999/03/31)
Indiana University School of Medicine Research Fellow(1999/04/01-2002/06/30)
Indiana University School of Medicine Post-Doctoral Fellow(2002/07/01-2002/10/31)
Indiana University School of Medicine Assistant Scientist(2002/11/01-2004/04/29)
Kanazawa University Graduate School of Natural Sci. & Tech. Senior Lecturer(2004/04/30-2006/03/31)
Kanazawa University Graduate School of Natural Sci. & Tech. Associate Professor(2006/04/01-2007/02/28)
Kanazawa University Institute of Nature & Enviro. Tech. Associate Professor(2007/03/01-2015/03/31)
Kanazawa University Faculty of Mechanical Engineering, Institute of Science and Engineering Associate Professor(2015/04/01-2015/09/30)
Kanazawa University Faculty of Mechanical Engineering, Institute of Science and Engineering Professor(2015/10/01-)

Year & Month of Birth

Academic Society

Japanese Society for Clinical Biomechanics
Japanese Society for Medical and Biological Engineering
The Japan Society of Mechanical Engineers

Award

○Oversea Research Fellowship, Japan Science and Technology Corporation(1999/03/28)
○Research grant, Izumi Foundation for Science and Technology(1996/09/01)
○NASA, 03-0BPR-04 BR&C Ground-based Research Proposal(2004/02/01)
○NIH, R01 Proposal(2004/04/15)
○NIH, R03 proposal(2004/09/01)
○Research for Promoting Technological Seeds(2006/09/01)
○Best Presentation Award, JSME Hokuriku-Shinetsu Branch(2007/03/08)
○Grand for Research in 2007, Tateisi Science and Technology Foundation(2007/03/28)
○Grand for Research in 2007, Tateisi Science and Technology Foundation(2007/03/28)
○Recognized Reviewer in recognition of the review made for the journal, Bone(2014/05)
○Outstanding Reviewer(2016/01)
○Recognized Reviewer in recognition of the review made for the journal, Bone(2017/05)

Specialities

Biomedical engineering/Biomaterial science and engineering、Materials/Mechanics of materials

Speciality Keywords

Biomedical Engineering, Biomechanics, Bone

Research Themes

Study on osteogenetic responses to mechanical stimulation

Development of a novel bone densitometer using near-infrared light

Study on osteogenic response to electrical stimulation

Books

Papers

  •  Osteoblast responses one hour after load-induced fluid flow in a three-dimensional porous matrix S. M. Tanaka, et al. CALCIFIED TISSUE INTERNATIONAL 76 4 261-271 2005/04
  •  Bone formation induced by a novel form of mechanical loading on joint tissue S. M. Tanaka, H. B. Sun, H. Yokota 18 2 41-44 2004/08
  •  Effects of high-impact mechanical loading on synovial cell cultures I. Sun, Y. Liu, S. M. Tanaka, et al. 3 37-43 2004/06
  •  Effects of broad frequency vibration on cultured osteoblasts S. M. Tanaka, J. Li, et al. JOURNAL OF BIOMECHANICS 36 1 73-80 2003/01
  •  Stochastic resonance in osteogenic response to mechanical loading S. M. Tanaka, M. I. Alam, C. H. Turner FASEB JOURNAL 17 2 313-314 2003/02

show all

  •  Intraocular pressure waves with exposure to pulsed Nd: YAG laser, the second and the third Harmonics Shigeo Tanaka 37 3 250-259 1999/06
  •  A new mechanical stimulator for cultured bone cells using piezoelectric actuator JOURNAL OF BIOMECHANICS 32 4 427-430 1999/04
  •  Analysis of intracellular calcium ion movement on osteoblast using confocal laser scanning microscope 17 409-413 1996/06
  •  Effects of pulse-vibration on the proliferation and the calcification of cultured osteoblasts 17 397-401 1996/10
  •  The effect of mechanical stimulation on the formation process of the bone-like tissue 34 4 331-334 1996/12
  •  Development of an apparatus applying mechanical stress to cultured osteoblasts 34 4 348-351 1996/06
  •  The finite element analysis involving trabecular structure 16 469-472 1995/08
  •  Mechanical properties of trabecular bone involving bone marrow 16 71-75 1995/08
  •  The effects of formalin preservation on the mechanical and AE properties of bone 15 1-6 1994/10
  •  Maintenance of bone mass by physical exercise after discontinuation of intermittent hPTH (1-34) administration 23 3 333-342 1993/12
  •  Failure characteristics of osteoporotic vertebral bodies monitored by acoustic emission SPINE 18 15 2314-2320 1993/11
  •  Failure characteristics of osteoporotic vertebral bodies 28 4 505-511 1993/04
  •  The effects of preservation on AE properties of bone 42 307-312 1993/11
  •  The influence of formalin preservation on AE responses and mechanical properties of long bone 14 217-220 1992/10
  •  Determination of a viscoelastic model of bone 40 259-266 1991/11
  •  Mechanical properties of osteopenic vertebral bodies monitored by acoustic emission BONE 14 5 737-743 1993/09
  •  Mechanical properties of osteoporotic vertebral bodies monitored by acoustic emission 13 99-103 1991/09
  •  Tensile force in soft tissue caused by callus distraction 11 215-219 1989/10
  •  Diaphyseal Bone Formation in Murine Tibiae in Response to Knee Loading P. Zhang, S.M. Tanaka, H. Jiang, M. Su, H. Yokota 100 5 1452-1459 2006/05
  •  Low-amplitude, broad-frequency vibration effects on cortical bone formation in mice A.B. Castillo, I. Alam, S.M. Tanaka, J. Levenda, J. Li, S.J. Warden, C.H. Turner BONE 39 5 1087-1096 2006/11
  •  Knee loading stimulates cortical bone formation in murine femurs P. Zhang, M. Su, S.M. Tanaka, H. Yokota BMC Musculoskeletal Disorders 7 73 0-0 2006/09
  •  Osteogenic potential with joint-loading modality H. Yokota, S.M. Tanaka JOURNAL OF BONE AND MINERAL METABOLISM 23 4 302-308 2005/06
  •  Bone densitometry by near-infrared spectroscopy .M. Tanaka, M. Nogawa, K. Yamakoshi 44 4 582-587 2006/12
  •  Development of a novel non-invasive bone densitometer using near-infrared lights 16 3 55-61 2006/12
  •  Frequency-dependent enhancement of bone formation in murine tibiae and femora with knee loading P. Zhang, S.M. Tanaka, Q. Sun, C.H. Turner, H. Yokota Journal of Bone and Mineral Metabolism 25 6  383-391 2007/11
  •  A novel bone densitometer using near-infrared light S.M. Tanaka, M. Nogawa, K. Yamakoshi, T. Tsujimoto Japanese Journal of Clinical Biomechanics 28  35-40 2007/11
  •  Non-destructive optical monitoring for calcification of tissue-engineered bone in vitro Shigeo M. Tanaka, Masafumi Kakio, Ken-ichi Yamakoshi Journal of Biomechanical Science and Engineering 3 3  332-342 2008/09
  •  Bone loss prevention by electrically-controlled muscle contraction Kanako Kondo, Takatomo Takimoto, Ken-ichi Yamakoshi, Shigeo M. Tanaka Japanese Journal of Clinical Biomechanics 29  199-204 2008/11
  •  Optical monitoring of in vitro calcification in tissue-engineered bone Masafumi Kakio, Naoki Sugiura, Ken-ichi Yamakoshi, Shigeo M. Tanaka Japanese Journal of Clinical Biomechanics 29  187-192 2008/11
  •  Development of optical bone densitometry - Compensation for skin variation by depth-resolved measurement - Shigeo. M. Tanaka, Tingshun Cao, Ken-ichi Yamakoshi, Toshiyuki Tsujimoto Japanese Journal of Clinical Biomechanics 29  181-186 2008/11
  •  Frequency and resting time dependencies of electrically-induced muscle contraction force Shigeo M. Tanaka and Kanako Kondo Journal of Biomechanical Science and Engineering 4 2  201-211 2009/05
  •  In vitro calcification of tissue engineered bone promoted by mechanical stimulation –Effect of cell seeding density and scaffold material-. Kohei Tachibana, Shigeo M. Tanaka Japanese Journal of Clinical Biomechanics 32 33-38 2011/10
  •  Moderate joint loading reduces degenerative actions of matrix metalloproteinases in the articular cartilage of mouse ulnae Hui B. Sun, Liming Zhao, Shigeo Tanaka, Hiroki Yokota Connective Tissue Research 53 2 180-186 2012/04
  •  Intracellular Ca2+ response of 3D-cultured osteoblasts subject to dynamic loading Shigeo M. Tanaka, Journal of Biomechanical Science and Engineering 7 3 318-327 2012/07
  •  Promotion of osteoblastic calcification by random pulse train electromagnetic fields Hiroyuki Matsumura, Shigeo M. Tanaka Japanese Journal of Clinical Biomechanics 33 41-46 2012/10
  •  Osteogenic effect of electrical muscle stimulation -Verification of the effect by finite element analysis of bone strain- Yuma Yorozuya. Jiro Sakamoto Shigeo M. Tanaka Japanese Journal of Clinical Biomechanics 34 71-76 2013/11
  •  Improvement of mechanical properties of tissue-engineered bone using a bovine trabecular bone ash scaffold-Intervention of electromagnetic field stimulation-, Yamashita Y., Tanaka SM. Proceedings of Life Engineering Symposium 2014 314-315 2014/09/17
  •  Effects of heating temperature on material properties of bovine trabecular bone ash scaffolds Tanaka SM., Yamashita Y. Proceedings of Life Engineering Symposium 2014 312-313 2014/09/17
  •  Effect of stimulation frequency on osteogenic capability of electrical muscle stimulation, Journal of Biomechanical Science and Engineering Shigeo M. Tanaka, Journal of Biomechanical Science and Engineering 9 3 14-00114 2014/12/26
  •  Frequency-dependence of mechanically stimulated osteoblastic calcification in tissue-engineered bone in vitro Shigeo M. Tanaka, Kohei Tachibana Annals of Biomedical Engineering 43 9 2083-2089 2015/01/07
  •  Random electromyostimulation promotes osteogenesis and the mechanical properties of rat bones Shigeo M. Tanaka, Yuma Yorozuya, Daisuke Takatsu Annals of Biomedical Engineering 45 12 2837-2846 2017/11/01

Conference Presentations

  • Development of high toughness composite material for bone regeneration using nano-calcined bone powder and alginate acid(2017/01/19)
  • Development of a mathematrical model to predict the non-linear response of a bone cell to physical stimulation(2016/04/26)
  • Electromagnetic field stimulation enhances mechanical properties of tissue-engineered bone constructed with calcined bovine trabecular bone scaffold(conference:2015 Summer Biomechanics, Bioengineering and Biotransport Conference)(2015/06/17)
  • Mathematical modeling of non-linear osteoblastic response to physical stimulation(conference:The 8th Asian-Pacific Conference on Biomechanics)(2015/09/16)
  • Effects of electromagnetic field stimulation on the mechanical properties of tissue-engineered bone(conference:The Sixth International Conference on Science and Engineering, 2015)(2015/12/12)

show all

  • Effect of electromagnetic field stimulation on the mechanical properties of tissue-engineered bone constructed with a calcined bovine trabecular bone scaffold(conference:The 8th Asian-Pacific Conference on Biomechanics)(2015/09/16)
  • Frequency-dependence in the osteogenic response of osteoblasts to mechanical loading in vitro(conference:7th World Congress of Biomechanics)(2014/07/06)
  • Comparison of near infrared spectroscopy method with DEXA for Bone density measurement(2016/01/09)
  • Preliminary light therapy to irradiated dysfunction SH-SY5Y cell by β-amyloid(2016/01/09)
  • Effects of calcination temperature on the bioabsorbability of calcined bovine bone scaffold material(2016/01/09)
  • Effects of calcination process on the bioabsorbability of bovine bone ash(2015/10/02)
  • Effect of calcination temperature on the components and mechanical properties of bovine trabecular bone ash scaffold(2015/01/09)
  • Tissue-engineered bone made of a bovine trabecular bone ash and improvement of the mechanical properties by electromagnetic field stimulation(2015/01/09)
  • Osteogenic effect of randomly pulsing electromagnetic field on the ovariectomised (OVX) rat model(2015/01/09)
  • Mathematical modeling of non-linear osteoblastic response to physical stimulation(2014/10/03)
  • Improvement of mechanical properties of tissue-engineered bone using a bovine trabecular bone ash scaffold-Intervention of electromagnetic field stimulation-(2014/09/17)
  • Effects of heating temperature on material properties of bovine trabecular bone ash scaffolds(2014/09/17)
  • Mechanical and morphological evaluation of the generative bone with bovine cancellous bone ash(2014/01/11)
  • Bone strain generated by electrically-induced muscle contraction and its osteogenic effect(2013/11/08)
  • Manufacturing of regenerative bone using a bovine trabecular bone ash as a scaffold(2013/11/01)
  • Development of optical bone densitometry using near-infrared light(conference:The 5th International Conference on Advances in Mechanical Engineering 2017 (ICAME 2017))(2017/08/16)
  • Development of optical bon edensitometry using near-infrared light(conference:Japan-Thailand Research Exchange Conference 2017)(2017/08/21)
  • Study on accuracy verification of optical bone densitometer(conference:Japan-Thailand Research Exchange Conference 2017)(2017/08/21)
  • The effects of electromagnetic field stimulation on cell distribution and calcification in tissue-engineered bone(conference:Japan-Thailand Research Exchange Conference 2017)(2017/08/21)
  • A new method to predict stress around dental implants using 3D-finite element method (FEM) with patient computed tomography images and bite force data(2017/06/15)
  • The effectiveness of electro-myostimulation at rat quadriceps in increasing the mechanical properties of the lumbar vertebrae,(2017/07/23)
  • Improvement of prediction accuracy of optical bone density measuring device by Machine Learning(2018/03/02)
  • Develop of new artificial bone material using composite material of calcined bone powder / alginate acid(2018/03/02)
  • Evaluation of bioabsorbability of calcined bone using cultured osteoclasts(2017/12/14)
  • Finite element analysis of implant-embedded mandibular model from patient data(conference:IADR/AADR/CADR GENERAL SESSION & EXHIBITION (the 95th General Session of IADR))(2017/03/25)
  • Study on the biosolubility of calcined bovine bone scaffold for bone tissue engineering(conference:2016 Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C2016))(2016/06/29)
  • Osteogenic Effect of Single-Position Electromyostimulation in a Whole-Body Scale(2017/03/09)

Arts and Fieldwork

Patent

Theme to the desired joint research

○Promotion of osteogenesis by electrical stimulation

Grant-in-Aid for Scientific Research

○「ひずみ誘導型液体流動を用いた力学刺激適応型再生骨培養システムの開発」(2006-2007) 
○「骨芽細胞培養系を用いた骨欠損部充填材の開発」(1995-) 
○「骨芽細胞活性化に与えるひずみ量およびひずみ速度の影響」(1998-) 
○「ひずみ誘導型液体流動による骨形成反応促進効果の実験的検証」(2008-2010) 
○「インプラント検討症例の残存歯咬合力を用いたヒト生体骨梁モデルの3次元有限要素解析」(2016-2018) 
○「灰化ウシ海綿骨を担体とする高力学適合性再生骨の開発」(2015-2018) 
○「光式骨密度計測装置の開発」(2014-2015)
○「骨の非線形力学刺激応答の検証とその数理モデル化」
○「ランダム性を有する物理刺激波形の骨形成促進効果の実験的検証」
○「力学的刺激の周波数チューニングによる骨形成促進の高効率化」

Classes (Bachelors)

○Fundamental Physics 1(2017)
○Bioengineering(2017)
○GS English Language for Undergraduates II (English for Science and Engineering)(2017)
○GS English Language for Undergraduates I (English for Science and Engineering)(2017)
○Topics in Mechanical Engineering(2017)
○Seminar on Mechanical Engineering(2017)
○Technical English Exercise(2017)
○Strength of Materials I and Exercise(2017)

Classes (Graduate Schools)

○Fundamentals of Biomechanics B(2017)
○Fundamentals of Biomechanics A(2017)
○Tissue Engineering(2017)
○Tissue Engineering(2017)
○Tissue Engineering(2017)
○Tissue Engineering(2017)

International Project

International Students

Lecture themes

Others (Social Activities)

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