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Researcher Information

last modified：2024/04/29

Professor　NAKADA Mitsutoshi

Mail Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences
Professor and Chairman

College and School Educational Field

Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Neurosurgery　TEL:076-265-2384　FAX:076-234-4262

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University　Doctor　Graduate School, Division of Medicine　199903　Completed
【Academic background(Bachelor's Degree)】
Kanazawa University　199403

Career

Kanazawa University(2001/04/01-)

Year & Month of Birth

Academic Society


The Japanese Congress of Neurological Surgeons

JCA

The Japan Society of Molecular Neurosurgery
American Association for Cancer Research










Japanese Society for Skull Base Surgery







Award

○Hokkoku Foundation for Cancer Research(2001/10/11)
○AACR Scholar-in-Training Award for the 93rd Annual Meeting(2002/04/09)
○Prize for Encouragement from Japan Neurosurgical Society(2002/10/02)
○The American Brain Tumor Association The Basic Research Fellowship Award(2002/10/06)
○Naito Foundation for young scientist(2002/10/06)
○Toyama Award(2003/05/09)
○“JSPS Fellowship Award” for Research Abroad(2005/04/01)
○Hoshino award(2005/10/31)
○AANS poster award(2006/04/26)
○Foundation for Promotion of Cancer Research(2007)
○Japan Brain Foundation(2008)
○Japan Research Foundation for Clinical Pharmacology(2008/12/10)
○The Yasuda Medical Foundation(2008/12/13)
○Foundation for Promotion of Cancer Research(2009/03/30)
○Juzen Medical Award(2010/10/08)
○Osaka Cancer Foundation(2010/12/01)
○Kobayashi Foundation for Cancer Research(2011/06/25)
○Research Award from Japan Research Foundation for Clinical Pharmacology(2011/11/14)
○Public Trust Surgery Research Fund(2012/08/10)
○Takeda Science Foundation(2012/11/12)
○Foundation for Promotion of Cancer Research(2013/01/23)
○The Hokuriku Industrial Advancement Center(2013/08/06)
○Mochida Memorial Foundation for Medical and Pharmaceutical Research(2013/10/25)
○Kanazawa Medical Association(2013/11/10)
○Princess Takamatsu Cancer Research Fund(2015/02/02)
○The Mitani Foundation for Research and Development(2015/07/02)
○Kobayashi International Scholarship Foundation(2017/02/23)
○Kobayashi International Scholarship Foundation(2018/02/21)
○Sugita Award(2022/03/10)
○BrainLab Neurosurgery Award (2021/10/19)

Specialities

Neurosurgery

Speciality Keywords

glioblastoma, brain function, glioma stem cell, invasion, molecular target, biomarker

Research Themes

The exploration of biomarker for malignant glioma

The exploration of biomarker for malignant glioma The useful biomarkers are needed for the malignant glioma because the early detection of the malignant glioma has a possibility to cure this miserable disease. We focus sphingosine-1-phosphate (S1P) which is a bioactive lipid that signals through a family of G protein-coupled receptors consisting of 5 members termed S1P1–5. S1P regulates cellular proliferation, migration, and survival. We recently reported that downregulation of S1P1 expression increases proliferative activity, and thus, enhances the malignancy of glioblastomas, resulting in a poor survival. Our results suggest S1P1 might be a useful biomarker for the malignant glioma.

Neuroscience based on awake surgery

Neuroscience based on awake surgery

Drug repositioning for malignant glioma

Drug repositioning for malignant glioma

The analysis of glioma stem cell biology

The analysis of glioma stem cell biology A characteristic of malignant glioma is their ability to infiltrate and invade the surrounding normal brain tissue. We have identified several molecules which are involved in glioma invasion, such as matrix degrading enzymes (MMP, ADAM and uPA), tyrosine kinases (Eph/ephrin), and intracellular signaling proteins (Rac/Rho). Recently, glioma stem cell has been identified and speculated as the cells which cause the recurrence. We have started to analyze the mechanism of glioma stem cell invasion.

TaylorMade molecular targeted therapy against malignant brain tumor

TaylorMade molecular targeted therapy against malignant brain tumor Glioblastoma, which is one of the most intractable tumors in human malignancies, is characterized by the remarkable proliferative activity and the invasive growth to the surrounding normal brain tissue. We recently revealed that inhibition of GSK3β　induces apoptosis and suppresses glioma growth. Based on the data from our basic　research, we have started the clinical trial entitled “Phase I/II study using GSK3β inhibitor against recurrent glioblastoma”. We are eager to engage in the translational research using our result of basic research.

Books

  • 　A Glimpse of Brain Functions　2023/07/12
  • 　The Handbook of Awake Surgery　2019/03/15
  • 　Nakada M, Kita D, Furuta T, Watanabe T, Hayashi Y, Hamada JI.　Signaling cascades driving the malignant phenotype of glioma cells　2014/10
  • 　Current applications of 5-ALA in glioma diagnostics and therapy　2013/01
  • 　Receptor tyrosine kinases: principles and functions in glioma invasion　2013/01

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  • 　Nakada M, Kita D, Hayashi Y, Hamada JI, Kawakami K, Minamoto T　RNAi in malignant brain tumors: relevance to molecular and translational research　Springer-Verlag Heidelberg　in press　2010/01
  • 　Tamai S, Hirai N, Jiapaer S, Furuta T, Nakada M.　Drug repositioning for treatment of glioma: current state and future perspective.　InTech　2020/07/14

Papers

  • 　Asymptomatic carotid intraplaque hemorrhage is associated with a high risk of cerebral infarction and death after cardiovascular surgery　Misaki K, Uno T, Nambu I, Kimura R, Yoshikawa A, Kamide T, Hayashi Y, Uchiyama N, Iino K, Takemura H, Nakada M.　J Neurol Sci.　2020/03
  • 　Recurrent spinal intramedullary arachnoid cyst: A case report and literature review　Ichinose T, Miyashita K, Tanaka S, Oikawa N, Oishi M, Nambu I, Kinoshita M, Nakada M　World Neurosurg　2020/03
  • 　Does the superior fronto-occipital fascicle exist in the human brain? Fiber dissection and brain functional mapping in 90 patients with gliomas　Liu X, Kinoshita M, Shinohara H, Hori O, Ozaki N, Nakada M　Neuroimage Clin.　2020/01
  • 　Integrated Clinical, Histopathological, and Molecular Data Analysis of 190 Central Nervous System Germ Cell Tumors from the iGCT Consortium　31. Takami H, Fukuoka K, Fukushima S, Nakamura T, Mukasa A, Saito N, Yanagisawa T, Nakamura H, Sugiyama K, Kanamori M, Tominaga T, Maehara T, Nakada M, Kanemura Y, Asai A, Takeshima H, Hirose Y, Iuchi T, Nagane M, Yoshimoto K, Matsumura A, Kurozumi K, Nakase H, Sakai K, Tokuyama T, Shibui S, Nakazato Y, Narita Y, Nishikawa R, Matsutani M, Ichimura K　Neuro-Oncology　21　1565-1577　2019/12
  • 　Progressively enlarged convexity arachnoid cysts in elderly patients: A report of two cases　Kimura R, Hayashi Y, Sasagawa Y, Kobayashi M, Oishi M, Nakada M　World Neurosurg 　2019/12

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  • 　Effect of unilateral carotid artery stenting on cognitive function in patients with severe bilateral stenosis: a case report 　Nakahara M, Misaki K, Tsutsui T, Nakajima R, Yoshikawa A, Miyashita K, Uchiyama N, Nakada M　World Neurosurg　2019/12
  • 　Method for the Detection of Tumor Blood Vessels in Neurosurgery Using a Gripping Force Feedback System　Yokota H, Yoneyama T, Watanabe T, Sasagawa Y, Nakada M　Sensors (Basel)　19　2019/11
  • 　Intratumoral continuous facial nerve stimulation for surgical resection of cystic vestibular schwannoma: Technical note　Miyashita K, Kimura R, Tamai S, Tanaka S, Kinoshita M, Hayashi Y, Nakada M　Surg Neurol Int　10　231　2019/11
  • 　Identification of Vortex Cores in Cerebral Aneurysms on 4D Flow MRI　Futami K, Uno T, Misaki K, Tamai S, Nambu I, Uchiyama N, Nakada M　AJNR Am J Neuroradiol 　2019/11
  • 　Soluble receptor for advanced glycation end products as a biomarker of symptomatic vasospasm in subarachnoid hemorrhage　Aida Y, Kamide T, Ishii H, Kitao Y, Uchiyama N, Nakada M, Hori O　J Neurosurg　2019/11
  • 　Fibulin-7 is over-expressed in glioblastomas and modulates glioblastoma neovascularization through interaction with angiopoietin-1　28. de Vega S, Kondo A, Suzuki M, Arai H, Jiapaer S, Sabit H, Nakada M, Ikeuchi T, Ishijima M, Arikawa-Hirasawa E, Yamada Y, Okada Y　Int J Cancer 　145　2157-2169　2019/10
  • 　Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a “spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant”　Sakaguchi M, Nakano Y, Honda-Kitahara M, Kinoshita M, Tanaka S, Oishi M, Noguchi K, Fukuda M, Maeba H, Watanabe T, Hayashi Y, Ikeda H, Minato H, Ichimura K, Nojima T, Nakada M　Brain Tumor Pathol　36　174-182　2019/10
  • 　Efficacy of cyst-cisternal shunt for refractory cyst regrowth of cystic vestibular schwannomas　Kimura R, Miyashita K, Tamai S, Kawahara Y, Nakada M　Acta Neurochir (Wien)　161　1817-1819　2019/09
  • 　Spinal accessory nerve meningioma at the foramen magnum with medullar compression: a case report and literature review　29. Mohri M, Yamano J, Miyamori T, Saito K, Nakada M.　World Neurosurg　128　158-161　2019/08
  • 　The superior longitudinal fascicle: Reconsidering the fronto-parietal neural network based on anatomy and function　Nakajima R, Kinoshita M, Shinohara H, Nakada M　Brain Imaging and Behavior 　2019/08
  • 　Awake surgery for glioblastoma can preserve independence level, but is dependent on age and the preoperative condition　Nakajima R, Kinoshita M, Okita H, Yahata T, Nakada M　J Neurooncol 　144　155-163　2019/08
  • 　Neuroprotective effects of endogenous secretory receptor for advanced glycation end-products in brain ischemia　Shimizu Y, Harashima1 A, Munesue S, Oishi M, Hattori T, Hori O, Kitao Y, Yamamoto H, Leerach N, Nakada M, Yamamoto Y, Hayashi Y　Aging and Disease 　2019/07
  • 　Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma　Kitabayashi T, Dong Y, Furuta T, Sabit H, Jiapaer S, Zhang J, Zhang G, Hayashi Y, Kobayashi M, Domoto T, Minamoto T, Hirao A, Nakada M　Sci Rep　9　10049　2019/07
  • 　Entirely suprasellar Rathke cleft cysts: clinical features and surgical efficacy of endoscopic endonasal transtuberculum sellae approach　Hayashi Y, Kobayashi M, Sasagawa Y, Oishi M, Tachibana O, Nakada M　World Neurosurg 　126　e921-e929　2019/06
  • 　Intratumoural immune cell landscape in germinoma reveals multipotent lineages and exhibits prognostic significance　Takami H, Fukushima S, Aoki K, Satomi K, Narumi K, Hama N, Matsushita Y, Fukuoka K, Yamasaki K, Nakamura T, Mukasa A, Saito N, Suzuki T, Yanagisawa T, Nakamura H, Sugiyama K, Tamura K, Maehara T, Nakada M, Nonaka M, Asai A, Yokogami K, Takeshima H, Iuchi T, Kanemura Y, Kobayashi K, Nagane M, Kurozumi K, Yoshimoto K, Matsuda M, Matsumura A, Hirose Y, Tokuyama T, Kumabe T, Ueki K, Narita Y, Shibui S, Totoki Y, Shibata T, Nakazato Y, Nishikawa R, Matsutani M, Ichimura K; Intracranial Germ Cell Tumor Genome Analysis Consortium (the iGCT Consortium).　Neuropathology and Applied Neurobiology　2019/06
  • 　A case of metastasis of a glioblastoma with primitive neuronal component to the lung　Tamai S, Kinoshita M, Sabit H, Furuta T, Miyashita K, Yoshimura K, Homma T, Harada K, Nakada M　39　218-223　2019/06
  • 　Ligand-dependent EphB4 activation serves as an anchoring signal in glioma cells　Kawahara Y, Furuta T, Sabit H, Tamai S, Yu D, Jiapaer S, Zhang J, Zhang G, Oishi M, Miyashita K, Hayashi Y, Nakada M　Cancer Letters　2019/05
  • 　Practical procedures for the integrated diagnosis of astrocytic and oligodendroglial tumors　Sonoda Y, Yokoo H, Tanaka S, Kinoshita M, Nakada M, Nishihara H, The committee for molecular diagnosis of the Japan Society of Brain Tumor Pathology　Brain Tumor Pathol　36　56-62　2019/04
  • 　MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma　Sakata J, Sasayama T, Tanaka K, Nagashima H, Nakada M, Tanaka H, Hashimoto N, Kagawa N, Kinoshita M, Nakamizo S, Maeyama M, Nishihara M, Hosoda K, Kohmura E　J Neurooncol　142　241-251　2019/04
  • 　Intraorbital solitary fibrous tumor requiring preoperative embolization of feeding artery　Demura M, Hayashi Y, Sasagawa Y, Mohri M, Takahira M, Nakada M　Asian J Neurosurg　14　593-597　2019/04
  • 　A case of metastasis of a glioblastoma with primitive neuronal component to the lung.　Tamai S, Kinoshita M, Sabit H, Furuta T, Miyashita K, Yoshimura K, Homma T, Harada K, Nakada M.　Neuropathology　2019/04/25
  • 　Radiological and endocrinological evaluations with grading of hypothalamic perifocal edema caused by craniopharyngiomas. 　Hayashi Y, Sasagawa Y, Oishi M, Misaki K, Kozaka K, Tachibana O, Nakada M.　Pituitary　22　146-155　2019/04/22
  • 　Fibulin-7 is over-expressed in glioblastomas and modulates glioblastoma neovascularization through interaction with angiopoietin-1.　de Vega S, Kondo A, Suzuki M, Arai H, Jiapaer S, Sabit H, Nakada M, Ikeuchi T, Ishijima M, Arikawa-Hirasawa E, Yamada Y, Okada Y.　Int J Cancer 　2019/03/28
  • 　Entirely suprasellar Rathke cleft cysts: clinical features and surgical efficacy of endoscopic endonasal transtuberculum sellae approach. 　Hayashi Y, Kobayashi M, Sasagawa Y, Oishi M, Tachibana O, Nakada M.　World Neurosurg 　2019/03/11
  • 　Practical procedures for the integrated diagnosis of astrocytic and oligodendroglial tumors　Sonoda Y, Yokoo H, Tanaka S, Kinoshita M, Nakada M, Nishihara H, The committee for molecular diagnosis of the Japan Society of Brain Tumor Pathology.　Brain Tumor Pathol.　36　56-62　2019/03/07
  • 　Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice.　Yamamoto Y, Liang M, Munesue S, Deguchi K, Harashima A, Furuhara K, Yuhi T, Zhong J, Akther S, Goto H, Eguchi Y, Kitao Y, Hori O, Shiraishi Y, Ozaki N, Shimizu Y, Kamide T, Yoshikawa A, Hayashi Y, Nakada M, Lopatina O, Gerasimenko M, Komleva Y, Malinovskaya N, Salmina AB, Asano M, Nishimori K, Shoelson SE, Yamamoto H, Higashida H.　Commun Biol.　2019/02/25
  • 　Ligand-dependent EphB4 activation serves as an anchoring signal in glioma cells.　Kawahara Y, Furuta T, Sabit H, Tamai S, Yu D, Jiapaer S, Zhang J, Zhang G, Oishi M, Miyashita K, Hayashi Y, Nakada M.　Cancer Letters 　449　 56-65　2019/02/15
  • 　Recovery time from supplementary motor area syndrome depends on postoperative 1 week paralysis and damage of the cingulum.　Nakajima R, Kinoshita M, Yahata T, Nakada M. 　J Neurosurg 　2019/02/08
  • 　Bright spot analysis for photodynamic diagnosis of brain tumors using confocal microscopy.　Yoneyama T, Watanabe T, Tamai S, Miyashita K, Nakada M.　Photodiagnosis Photodyn Ther. 　25　463-471　2019/02/06
  • 　Bright spot analysis for photodynamic diagnosis of brain tumors using confocal microscopy　Yoneyama T, Watanabe T, Tamai S, Miyashita K, Nakada M　Photodiagnosis Photodyn Ther　25　463-471　2019/02
  • 　Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice　Yamamoto Y, Liang M, Munesue S, Deguchi K, Harashima A, Furuhara K, Yuhi T, Zhong J, Akther S, Goto H, Eguchi Y, Kitao Y, Hori O, Shiraishi Y, Ozaki N, Shimizu Y, Kamide T, Yoshikawa A, Hayashi Y, Nakada M, Lopatina O, Gerasimenko M, Komleva Y, Malinovskaya N, Salmina AB, Asano M, Nishimori K, Shoelson SE, Yamamoto H, Higashida H　Commun Biol　2　76　2019/02
  • 　A suprasellar colloid cyst over an 11-year follow-up: case report and literature review　Uno T, Hayashi Y, Sasagawa Y, Miyamori T, Oishi M, Nakada M　World Neurosurgery　2019/01
  • 　MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma.　Sakata J, Sasayama T, Tanaka K, Nagashima H, Nakada M, Tanaka H, Hashimoto N, Kagawa N, Kinoshita M, Nakamizo S, Maeyama M, Nishihara M, Hosoda K, Kohmura E.　J Neurooncol 　142　241-251　2019/01/30
  • 　A case of suprasellar colloid cyst over an 11-year follow-up.　Uno T, Hayashi Y, Sasagawa Y, Miyamori T, Oishi M, Nakada M.　World Neurosurg 　2019/01/18
  • 　A suprasellar colloid cyst over an 11-year follow-up: case report and literature review.　Uno T, Hayashi Y, Sasagawa Y, Miyamori T, Oishi M, Nakada M.　World Neurosurgery　2019/01/18
  • 　Glioma surgery under awake condition can lead to good independence and functional outcome excluding deep sensation and visuospatial cognition. 　Nakajima R, Kinoshita M, Okita H, Yahata T, Nakada M.　Neurooncol Pract　2018/12/20
  • 　Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors.　Fukuoka K, Kanemura Y, Shofuda T, Fukushima S, Yamashita S, Narushima D, Kato M, Honda-Kitahara M, Ichikawa H, Kohno T, Sasaki A, Hirato J, Hirose T, Komori T, Satomi K, Yoshida A, Yamasaki K, Nakano Y, Takada A, Nakamura T, Takami H, Matsushita Y, Suzuki T, Nakamura H, Makino K, Sonoda Y, Saito R, Tominaga T, Matsusaka Y, Kobayashi K, Nagane M, Furuta T, Nakada M, Narita Y, Hirose Y, Ohba S, Wada A, Shimizu K, Kurozumi K, Date I, Fukai J, Miyairi Y, Kagawa N, Kawamura A, Yoshida M, Nishida N, Wataya T, Yamaoka M, Tsuyuguchi N, Uda T, Takahashi M, Nakano Y, Akai T, Izumoto S, Nonaka M, Yoshifuji K, Kodama Y, Mano M, Ozawa T, Ramaswamy V, Taylor MD, Ushijima T, Shibui S, Yamasaki M, Arai H, Sakamoto H, Nishikawa R, Ichimura K; Japan Pediatric Molecular Neuro-Oncology Group (JPMNG).　Acta Neuropathol Commun 　2018/12/04
  • 　Enlargement of Langerhans cell histiocytosis of the hypothalamus with progression into the basal ganglia and white matter.　23. Tamai S, Ueno M, Hayashi Ya, Sasagawa Y, Watanabe T, Murakami KI, Nakada M, Hayashi Yu.　Surg Neurol Int 　2018/10/03
  • 　Directional regulation of extrasellar extension by sellar dura integrity and intrasphenoidal septation in pituitary adenomas. 　Hayashi Y, Sasagawa Y, Oishi M, Kita D, Ueda F, Tachibana O, Nakada M.　World Neurosurg　2018/09/26
  • 　Potential strategies overcoming the temozolomide resistance for glioblastoma.　Jiapaer S, Furuta T, Tanaka S, Kitabayashi T, Nakada M.　Neurol Med Chir (Tokyo) 　58　2018/09/21
  • 　RUNX2 promotes malignant progression in glioma.　Yamada D, Fujikawa K, Kawabe K, Furuta T, Nakada M, Takarada T.　Neurochem Res 　2018/09/10
  • 　Effectiveness of modified dural incision to preserve the patency of the occipital sinus in foramen magnum decompression for a patient with Chiari malformation type I.　Hayashi Y, Fukui I, Sasagawa Y, Misaki K, Oishi M, Nakada M.　Surg Neurol Int 　9　2018/08/03
  • 　Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.　Vu HT, Kobayashi M, Hegazy AM, Tadokoro Y, Ueno M, Kasahara A, Takase Y, Nomura N, Peng H, Ito C, Ino Y, Todo T, Nakada M, Hirao A.　Cancer Sci 　2018/07/26
  • 　Transsphenoidal surgery for elderly patients with acromegaly and its outcomes: comparison with younger patients.　Sasagawa Y, Hayashi Y, Tachibana O, Nakagawa A, Oishi M, Takamura T, Iizuka H, Nakada M.　World Neurosurg 　2018/06/30
  • 　A de novo mouse model of C11orf95-RELA fusion-driven ependymoma identifies driver functions in addition to NFκB.　Ozawa T, Arora S, Szulzewsky F, Juric-Sekhar G, Miyajima Y, Bolouri H, Yasui Y, Barber J, Kupp R, Dalton J, Jones TS, Nakada M, Kumabe T, Ellison DW, Gilbertson RJ, Holland EC.　Cell Reports 　2018/06/26
  • 　Evaluation of soft tissue hypertrophy at the retro-odontoid space in patients with Chiari malformation type I on magnetic resonance imaging.　Hayashi Y, Oishi M, Sasagawa Y, Kita D, Kozaka K, Nakada M.　World Neurosurg　116　2018/06/02
  • 　Hyperperfusion syndrome after trapping with high-flow bypass for a giant paraclinoid internal carotid artery aneurysm.　Mohri M, Ichinose T, Uchiyama N, Misaki K, Nambu I, Takabatake Y, Nakada M.　World Neurosurg　116　143-146　2018/04/22
  • 　Contribution of intrasellar pressure elevation to headache manifestation in pituitary adenoma evaluated with intraoperative pressure measurement　Hayashi Y, Sasagawa Y, Oishi M, Kita D, Misaki K, Fukui I, Tachibana O, Nakada M　Neurosurgery 　2018/03/29
  • 　High pressure in virtual post-coiling model is a predictor of internal carotid artery aneurysm recurrence after coiling　Nambu I, Misaki K, Uchiyama N, Mohri M, Suzuki T, Takao H, Murayama Y, Futami K, Kawamura T, Inoguchi Y, Matsuzawa T, Nakada M.　Neurosurgery 　2018/03/15
  • 　Clinicopathological and genetic association between epithelioid glioblastoma and pleomorphic xanthoastrocytoma　Furuta T, Miyoshi H, Komaki S, Arakawa F, Morioka M, Ohshima K, Nakada M, Sugita Y　Neuropathol.　2018/03/13
  • 　Activation of the receptor tyrosine kinase AXL mediates the immune microenvironment in glioblastoma　Sadahiro H, Kang KD, Gibson JT, Minata M, Yu H, Shi J, Chhipa R, Chen Z, Lu S, Simoni Y, Furuta T, Sabit H, Zhang S, Bastola S, Yamaguchi S, Alsheikh HA, Komarova S, Wang J, Kim SH, Hambardzumyan D, Lu X, Newell EW, DasGupta B, Nakada M, Lee LJ, Nabors B, Norian LA, Nakano I　Can Res.　2018/03/12
  • 　Objective evaluation of cerebrovascular reactivity for acetazolamide predicts cerebral hyperperfusion after carotid artery stenting: Comparison with region of interest methods　Misaki K, Uchiyama N, Inaki A, Kinuya S, Nambu I, Kamide T, Mohri M, Hayashi Ya, Nakada M　J Neuroradiol 　2018/03/07
  • 　Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics　Miyauchi E, Furuta T, Ohtsuki S, Tachikawa M, Uchida Y, Sabit H, Obuchi W, Baba T, Watanabe M, Terasaki T, Nakada M　PLOS ONE　13　3　e0193799　2018/03/07
  • 　Outcome of diabetes insipidus in patients with Rathke cleft cysts　Oishi M, Hayashi Y, Sasagawa Y, Kita D, Tachibana O, Nakada M　Clin Neurol Neurosurg　2018/02/21
  • 　N-myc downstream-regulated gene 2 protects blood-brain barrier integrity following cerebral ischemia　Takarada-Iemata M, Yoshikawa A, Hieu TM, Okitani N, Nishiuchi T, Aida Y, Kamide T, Hattori T, Ishii H, Kitao Y, Matsuyama T, Nakada M, Hori O　Glia　2018/02/12
  • 　Physical risk factors of hemorrhagic complications associated with Angio-Seal closure device use in neurointerventional procedures　Aida Y, Misaki K, Kamide T, Mohri M, Uchiyama N, Nakada M　World Neurosurgery　2018/01/08
  • 　Delayed occurrence of diabetes insipidus following transsphenoidal surgery with radiological evaluation of the pituitary stalk on magnetic resonance imaging　Hayashi Y, Aida Y, Sasagawa Y, Oishi M, Kita D, Tachibana O, Ueda F, Nakada M　World Neurosurgery　110　e1072-e1077　2018
  • 　A case of a mobile choroid plexus cyst presenting with different types of obstructive hydrocephalus　Tamai S, Hayashi Y, Sasagawa Y, Oishi M, Nakada M　Surg Neurol Int 　9　47　2018
  • 　Neural networks mediating high-level mentalizing in patients with right cerebral hemispheric gliomas　Nakajima R, Kinoshita M, Okita H, Yahata T, Matsui M, Nakada M　Front Behav Neurosci 　12　33　2018
  • 　ROCK-dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation　Hazawa M, Lin DC, Kobayashi A, Jiang YY, Xu L, Dewi F, Mohamed M, Hartono H, Nakada M, Meguro-Horike M, Horike S, Koeffler HP, Wong R　EMBO Reports　19　73-88　2018
  • 　CNS high-grade neuroepithelial tumor with BCOR internal tandem duplication: a comparison with its counterparts in the kidney and soft tissue　Yoshida Y, Nobusawa S, Nakata S, Nakada M, Arakawa Y, Mineharu Y, Sugita Y, Yoshioka T, Araki A, Sato Y, Okada M, Nishi A, Yamazaki T, Kohashi K, Oda Y, Hirato J, Yokoo H　Brain Pathology　2017/12/11
  • 　Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas　Fukushima S, Yamashita S, Kobayashi H, Takami H, Fukuoka K, Nakamura T, Yamasaki K, Matsushita Y, Nakamura H, Totoki Y, Kato M, Suzuki T, Mishima K, Yanagisawa T, Mukasa A, Saito N, Kanamori M, Kumabe T, Tominaga T, Nagane M, Iuchi T, Yoshimoto K, Mizoguchi M, Tamura K, Sakai K, Sugiyama K, Nakada M, Yokogami K, Takeshima H, Kanemura Y, Matsuda M, Matsumura A, Kurozumi K, Ueki K, Nonaka M, Asai A, Kawahara N, Hirose Y, Takayama T, Nakazato Y, Narita Y, Shibata T, Matsutani M, Ushijima T, Nishikawa R, Ichimura K; Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)　Acta Neuropathologica　133　445-462　2017
  • 　Rathke cleft cyst with entirely ossified cyst wall and partially solid cyst content: a case report and literature review　World Neurosurgery　98　e15-882,e20　2017
  • 　Preoperative evaluation of the interface between tuberculum sellae meningioma and the optic nerves on fast imaging with steady-state acquisition for extended endoscopic endonasal transsphenoidal surgery　Hayashi Y, Kita D, Fukui I, Sasagawa Y, Oishi Y, Tachibana O, Ueda F, Nakada M.　World Neurosurgery 　103　153-160　2017
  • 　Contribution of sellar dura integrity to symptom manifestation in pituitary adenomas with intratumoral hemorrhage　Hayashi Y, Sasagawa Y, Kita D, Fukui I, Oishi M, Tachibana O, Nakada M　Pituitary 　20　5　531-538　2017
  • 　Delayed occurrence of diabetes insipidus following transsphenoidal surgery with radiological evaluation of the pituitary stalk on magnetic resonance imaging　Hayashi Y, Aida Y, Sasagawa Y, Oishi M, Kita D, Tachibana O, Ueda F, Nakada M　World Neurosurgery　2017
  • 　Unique venous drainage of a sphenoid wing dural arteriovenous fistula with ocular symptoms　Misaki K, Uchiyama N, Mohri M, Aida Y, Uno T, Nakada M　World Neurosurg　97　753.e1-753.e5　2017
  • 　Clinical characteristics of acromegalic patients with empty sella and their outcomes following transsphenoidal surgery　Sasagawa Y, Hayashi Y, Tachibana O, Oishi M, Fukui I, Iizuka H, Nakada M　Pituitary　20　4　403-408　2017
  • 　Concurrent cervical dural and multiple perimedullary arteriovenous fistulas presenting with subarachnoid hemorrhage: The source of bleeding was invisible at initial angiography　Nambu I. Uchiyama N, Misaki K, Mohri M, Nakada M　Surgical Neurology International　8　2　2017
  • 　Radiation-induced gliomas: a report of four cases and analysis of molecular biomarkers　Nakao T, Sasagawa Y, Nobusawa S, Takabatake Y, Sabit H, Kinoshita M, Miyashita K, Hayashi Y, Yokoo H, Nakada M　Brain Tumor Pathol　34　10　149-154　2017
  • 　Intraoperative Rupture of Unruptured Cerebral Aneurysm during Craniotomy: A Case Report　Yoshiki K, Misaki K, Nambu I, Fukui I, Mohri M, Uchiyama N, Nakada M　Case Rep Neurol　9　261–266　2017
  • 　Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug　Dong Y, Furuta T, Sabit H, Kitabayashi T, Jiapaer S, Kobayashi M, Ino Y, Todo T, Teng L, Hirao A, Zhao SG, Nakada M　Oncotarget　8　111728-111741　2017
  • 　Biological basis and clinical trial of glycogen synthase kinase-3β-targeted therapy by drug repositioning for glioblastoma　Furuta T, Sabit H, Yu D, Miyashita K, Kinoshita M, Uchiyama N, Hayashi Y, Hayashi Y, Minamoto T, Nakada M　Oncotarget　8　22811-22824　2017
  • 　Inflow hemodynamics evaluated by using four-dimensional flow magnetic resonance imaging and the size ratio of unruptured cerebral aneurysms　Futami K, Nambu I, Kitabayashi T, Misaki K, Uchiyama N, Ueda F, Nakada M　Neuroradiology 　59　411-418　2017
  • 　Fluorescence intensity and bright spot analyses using confocal microscope for photodynamic diagnosis of brain tumors　Yoneyama T, Watanabe T, Kagawa H, Hayashi Y, Nakada M　Photodiagnosis Photodyn Ther　17　13-21　2017
  • 　MR spectroscopy to distinguish between supratentorial intraventricular subependymoma and central neurocytoma　Ueda F, Aburano H, Ryu Y, Yoshie Y, Nakada M, Hayashi Y, Matsui O, Gabata T　Magn Reson Med Sci　16　223-230　2017
  • 　Force-visualized silicone retractor attachable to surgical suction pipes　Watanabe T, Koyama T, Yoneyama T, Nakada M　Sensors (Basel) 　17　2017
  • 　Long spinal cord lesions in a patient with pathologically proven multiple sclerosis　Komatsu J, Sakai K, Nakada M, Iwasa K, Yamada M　Journal of Clinical Neuroscience　42　106-108　2017
  • 　Multiple sclerosis showing elevation of adenosine deaminase levels in the cerebrospinal fluid.　Samuraki M, Sakai K, Odake Y, Yoshita M, Misaki K, Nakada M, Yamada M　Mult Scler Relat Disord　13　 44-46　2017
  • 　Damage of the right dorsal superior longitudinal fascicle by awake surgery for glioma causes persistent visuospatial dysfunction　Nakajima R, Kinoshita M, Miyashita K, Okita H, Genda R, Yahata T, Hayashi Y, Nakada M　Sci Rep　7　17158　2017
  • 　In vivo imaging xenograft models for the evaluation of anti-brain-tumor efficacy of targeted drugs　Kita K, Arai1 S, Nishiyama A, Taniguchi H, Fukuda K, Wang R, Yamada T, Takeuchi S, Tange S, Tajima A, Nakada M, Yasumoto K, Motoo Y, Murakami T, Yano S　Cancer Medicine　6　2972-2983　2017
  • 　Descent of the anterior communicating artery after removal of pituitary macroadenoma using transsphenoidal surgery　Hayashi Y, Sasagawa Y, Fukui I, Oishi M, Kita D, Misaki K, Kozaka K, Tachibana O, Nakada M　Surg Neurol Int　8　306　2017
  • 　Rathke cleft cyst with entirely ossified cyst wall and partially solid cyst content: a case report and literature review.　Hayashi Y, Oishi M, Fukui I, Kita D, Sasagawa Y, Aida Y, Tachibana O, Nakada M 　World Neurosurgery　2017/02
  • 　Acute progression of recurrent meningioma during luteinizing hormone-releasing hormone agonist treatment for prostate cancer　Tsutsui T, Miyashita K, Sabit H, Fukui I, Hayashi Y, Mizokami A, Ikeda H, Nagatani H, Nakada M　World Neurosurg 　91　670　e1-6　2016
  • 　Simultaneous ventriculoperitoneal shunt removal and endoscopic third ventriculostomy for three patients previously treated for intracranial germ cell tumors more than 20 years ago　Kita D, Hayashi Y, Fukui I, Oishi M, Nakada M　Child's Nervous System　32　1543-7　2016
  • 　Xanthomatous hypophysitis associated with autoimmune disease in an elderly patient: A rare case report　Oishi M, Hayashi Y, Fukui I, Kita D, Miyamori T, Nakada M　Surg Neurol Int 　7　S449-453 　2016
  • 　Simple classification of carotid bifurcation: is it possible to predict twisted carotid artery during carotid endarterectomy?　Kamide T, Nomura M, Tamase A, Mori K, Seki S, Kitamura Y, Nakada M.　Acta Neurochirurgica (Wien) 　158 　2393-2397 　2016
  • 　Prediction of postoperative diabetes insipidus using morphological hyperintensity patterns in the pituitary stalk on magnetic resonance imaging after transsphenoidal surgery for sellar tumors　Hayashi Y, Kita D, Watanabe T, Fukui I, Sasagawa Y, Oishi M, Tachibana O, Ueda F, Nakada M.　Pituitary 　19　552-559　2016
  • 　Treatment result of in the initial stage of Kanazawa Mobile Embolectomy Team for acute ischemic stroke　Uchiyama N, Misaki K, Mohri M, Kamide T, Hirota Y, Higashi R, Minamide H, Kohda Y, Asahi T, Shoin K, Iwato M, Kita D, Hamada H, Yoshida Y, Nakada M.　Neurol Med Chir (Tokyo) 　56　737-744　2016
  • 　Critical neural networks in awake surgery for gliomas.　Kinoshita M, Miyashita K, Tsutsui T, Furuta T, Nakada M　Neurol Med Chir (Tokyo) 　56　674-686　2016
  • 　Chronic spatial working memory deficit associated with the superior longitudinal fasciculus: a study using voxel-based lesion-symptom mapping and intraoperative direct stimulation in the right prefrontal glioma surgery　Kinoshita M, Nakajima R, Shinohara H, Miyashita K, Tanaka S, Okita H, Nakada M , Hayashi Y.　J Neurosurg 　125　1024-1032　2016
  • 　Pseudoaneurysm formation caused by the withdrawal of a Trevo ProVue stent at a tortuous cerebral vessel: a case report　Misaki K, Uchiyama N, Mohri M, Kamide T, Tsutsui T, Kanamori N, Kurokawa K, Nakada M　Acta Neurochirurgica　158　2085-2088　2016
  • 　Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy　Domoto T, Pyko IV, Furuta T, Miyashita K, Uehara M, Shimasaki T, Nakada M, Minamoto T.　Cancer Sci. 　107　1363-1372 　2016
  • 　The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression.　Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein BG.　J Neurooncol. 　130　43-52,　2016
  • 　Force-sensible silicone retractor for attachment to surgical suction pipes.　Watanabe T, Koyama T, Yoneyama T, Nakada M　Sensors (Basel)　16　2016
  • 　miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.　Sakr M, Takino T, Sabit H, Nakada M, Li Z, Sato H　Gene 　587　155-62　2016
  • 　High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells.　Nanjo S, Ebi H, Arai S, Takeuchi S, Yamada T, Mochizuki S, Okada Y, Nakada M, Murakami T, Yano S.　Oncotarget 　7　3847-3856　2016
  • 　Fluorescence intensity and bright spot analyses using confocal microscope for photodynamic diagnosis of brain tumors 　Yoneyama T, Watanabe T, Kagawa H, Hayashi Y, Nakada M　Photodiagnosis Photodyn Ther. 　2016
  • 　MR spectroscopy to distinguish between supratentorial intraventricular subependymoma and central neurocytoma.　Ueda F, Aburano H, Ryu Y, Yoshie Y, Nakada M, Hayashi Y, Matsui O, Gabata T.　Magn Reson Med Sci.　2016
  • 　Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-κB pathway.　Takino T, Nakada M, Li Z, Yoshimoto T, Domoto T, Sato H.　Clin Exp Metastasis　33　45-52　2016
  • 　Intracranial aneurysm formation after radiotherapy for medulloblastoma.　Kamide T, Mohri M, Misaki K, Uchiyama N, Nakada M　Surg Neurol Int 　7　S880-S882　2016
  • 　Establishment of anti-human ATRX monoclonal antibody AMab-6　Ogasawara S, Fujii Y, Kaneko MK, Oki H, Sabit H, Nakada M, Suzuki H, Ichimura K, Komori T, Kato Y.　Monoclon Antib Immunodiagn Immunother. 　35　254-258　2016
  • 　Volumetric growth analysis of an insular dysembryoplastic neuroepithelial tumor over a 10-year follow-up　Uno T, Kinoshita M, Furuta T, Miyashita K, Sabit H, Nakada M　Surg Neurol Int 　7 　S1154-1157 　2016
  • 　Midline dural filum of the sellar floor; its relationship to the septum attachment to the sellar floor and the ossification in the sphenoid sinus　Hayashi Y, Kita D, Iwato M, Fukui I, Sasagawa Y, Oishi M, Tachibana O, Nakada M.　Clin Neurol Neurosurg 　147　53-58　2016
  • 　Pediatric symptomatic Rathke cleft cyst compared to cystic craniopharyngioma　Hayashi Y, Kita D, Fukui I, Sasagawa Y, Oishi M, Okajima M, Tachibana O, Nakada M.　Child's Nervous System　32　1625-32　2016
  • 　Inflow jet patterns of unruptured cerebral aneurysms based on flow velocity of the parent artery: evaluation using 4D flow MRI.　Futami K, Shimizu Y, Kitabayashi T, Sano H, Misaki K, Uchiyama N, Ueda F, Nakada M. 　37　2016
  • 　Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy"　Ichimura K, Fukushima S, Totoki Y, Matsushita Y, Otsuka A, Tomiyama A, Niwa T, Takami H, Nakamura T, Suzuki T, Fukuoka K, Yanagisawa T, Mishima K, Nakazato Y, Hosoda F, Narita Y, Shibui S, Yoshida A, Mukasa A, Saito N, Kumabe T, Kanamori M, Tominaga T, Kobayashi K, Shimizu S, Nagane M, Iuchi T, Mizoguchi M, Yoshimoto K, Tamura K, Maehara T, Sugiyama K, Nakada M, Sakai K, Kanemura Y, Nonaka M, Asai A, Yokogami K, Takeshima H, Kawahara N, Takayama T, Yao M, Kato M, Nakamura H, Hama N, Sakai R, Ushijima T, Matsutani M, Shibata T, Nishikawa R, Intracranial Germ Cell Tumor Genome Analysis Consortium (iGCT Consortium)　Acta Neuropathologica 131: 889-901, 2016　131　889-901　2016
  • 　Serine/Threonine kinase MLK4 determines Mesenchymal Identity in Glioma Stem Cells in an NFkB-dependent manner　Kim SH, Ezhilarasan R, Chhipa R, Ladner K, Phillips E, Sparks A, Taylor D, Furuta T, Sabit H, Kurozumi K, Kuroiwa T, Akio A, Gallego-Perez1 D, Sulman EP, Cheng S, Lee J, Nakada M, Guttridge D, DasGupta B, Goidts V, Bhat KP, Walker J, Nakano I.　Cancer Cell 　29　201-213　2016
  • 　Prediction of carotid artery in-stent restenosis by quantitative assessment of vulnerable plaque using computed tomography. 　Misaki K, Uchiyama N, Mohri M, Hayashi Y, Ueda F, Nakada M　J Neuroradiol 43: 18-24, 2016 　43　18-24　2016
  • 　Optimizing the volume of the initial framing coil to facilitate tight packing of intracranial aneurysms　Misaki K, Uchiyama N, Nambu I, Aida Y, Kamide T, Mohri M, Ueda F, Nakada M　World Neurosurg 　90　397-402　2016
  • 　Carotid artery protrusion and dehiscence in patients with acromegaly　Sasagawa Y, Tachibana O, Doai M, Hayashi Y, Tonami H, Iizuka H, Nakada M.　Pituitary 　19:　482-7　2016
  • 　Cerebral infarction related to carmustine wafers in glioblastoma　Neurol Med Chir (Tokyo)　2　1　36-39　2015/01
  • 　Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells　Tanaka, Shingo; Nakada, Mitsutoshi; Yamada, Daisuke; Nakano, Ichiro; Todo, Tomoki; Ino, Yasushi; Hoshii, Takayuki; Tadokoro, Yuko; Ohta, Kumiko; Ali, Mohammed Aamir E; Hayashi, Yutaka; Hamada, Junichiro; Hirao, Atsushi　Journal of Neuro-Oncology　2014/10/08
  • 　Functional recovery from pure dyslexia with preservation of subcortical association fiber networks　Interdisciplinary Neurosurgery　1　3　59-62　2014/09
  • 　Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation　Brain Tumor Pathol　31　172-176　2014/08
  • 　The mechanism of chemoresistance against tyrosine kinase inhibitors in malignant glioma　Brain Tumor Pathol　31　198-207　2014/08
  • 　Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems　J Neurol Sci　in press　2014/07
  • 　Membrane-type 1 matrix metalloproteinase regulates fibronectin assembly and N-cahderin adhesion　Biochem Biophys Res Commun　2014/06
  • 　Identification of the inflow zone of unruptured cerebral aneurysms: comparison of four-dimensional flow MRI- and three-dimensional TOF MRA data　AJNR Am J Neuroradiol,　2014/05
  • 　Prognostic paradox: Brain damage around the glioblastoma resection cavity　J Neurooncol　118　187-192　2014/05
  • 　Reversible acute bilateral blindness resulting from a frontal brain tumor: A case report　Br J Neurosurg　1-3　2014/05
  • 　PCDH10 is required for the tumorigenicity of glioblastoma cells　Biochem Biophys Res Commun　444　13-18　2014/01
  • 　Characterizing invading glioma cells based on IDH1-R132H and Ki-67 immunofluorescence　Brain Tumor Pathol　2014/01
  • 　PCDH10 is required for the tumorigenicity of glioblastoma cells　Echizen, Kanae; Nakada, Mitsutoshi; Hayashi, Tomoatsu; Sabit, Hemragul; Furuta, Takuya; Nakai, Miyuki; Koyama-Nasu, Ryo; Nishimura, Yukiko; Taniue, Kenzui; Morishita, Yasuyuki; Hirano, Shinji; Terai, Kenta; Todo, Tomoki; Ino, Yasushi; Mukasa, Akitake; Takayanagi, Shunsaku; Ohtani, Ryohei; Saito, Nobuhito; Akiyama, Tetsu　Biochemical and Biophysical Research Communications　444　1　13-18　2014/01/31
  • 　Prognostic paradox: Brain damage around the glioblastoma resection cavity　Furuta, Takuya; Nakada, Mitsutoshi; Ueda, Fumiaki; Watanabe, Takuya; Arakawa, Yasuaki; Higashi, Ryo; Hashimoto, Masaaki; Nitta, Hisashi; Hayashi, Yutaka; Hamada, Junichiro　Journal of Neuro-Oncology　118　1　187-192　2014/01/01
  • 　Functional reorganization in the patient with progressing glioma of the pure primary motor cortex: A case report with special reference to the topographic central sulcus defined by somatosensory-evoked potential　Hayashi, Yutaka; Nakada, Mitsutoshi; Kinoshita, Masashi; Hamada, Junichiro　World Neurosurgery　82　3　5360-5360000　2014/01/01
  • 　Reversible acute bilateral blindness resulting from a frontal brain tumor: A case report　Hayashi, Koji; Nakada, Mitsutoshi; Miyashita, Katsuyoshi; Hayashi, Yutaka; Hamada, Junichiro　British Journal of Neurosurgery　28　6　793-795　2014/01/01
  • 　Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems　Akagi, Akio; Ono, Kenjiro; Hamaguchi, Tsuyoshi; Samuraki, Miharu; Nakada, Mitsutoshi; Shima, Yukiko; Oohata, Tetuya; Yamada, Masahito　Journal of the Neurological Sciences　345　1　267-268　2014/01/01
  • 　Molecular analysis of a recurrent glioblastoma treated with bevacizumab　Furuta, Takuya; Nakada, Mitsutoshi; Misaki, Kouichi; Sato, Yasunori; Hayashi, Yutaka; Nakanuma, Yasuni; Hamada, Junichiro　Brain Tumor Pathology　31　1　32-39　2014/01/01
  • 　Direct evidence for the causal role of the left supplementary motor area in working memory: A preliminary study　Nakajima, Riho; Okita, Hirokazu; Kinoshita, Masashi; Miyashita, Katsuyoshi; Nakada, Mitsutoshi; Yahata, Tetsutaro; Hamada, Junichiro; Hayashi, Yutaka　Clinical Neurology and Neurosurgery　126　201-204　2014/01/01
  • 　Identification of the inflow zone of unruptured cerebral aneurysms: Comparison of 4D flow MRI and 3D TOF MRA data　Futami, Kazuya; Sano, Hirotoshi; Misaki, Kouichi; Nakada, Mitsutoshi; Ueda, Fumiaki; Hamada, Junichiro　American Journal of Neuroradiology　35　7　1363-1370　2014/01/01
  • 　Characterizing invading glioma cells based on IDH1-R132H and Ki-67 immunofluorescence　Sabit, Hemragul; Nakada, Mitsutoshi; Furuta, Takuya; Watanabe, Takuya; Hayashi, Yutaka; Sato, Hiroshi; Kato, Yukinari; Hamada, Junichiro　Brain Tumor Pathology　31　4　242-246　2014/01/01
  • 　The mechanism of chemoresistance against tyrosine kinase inhibitors in malignant glioma　Nakada, Mitsutoshi; Kita, Daisuke; Watanabe, Takuya; Hayashi, Yutaka; Hamada, Junichiro　Brain Tumor Pathology　31　3　198-207　2014/01/01
  • 　Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation　Tanaka, Shingo; Nakada, Mitsutoshi; Nobusawa, Sumihito; Suzuki, Satoshi O.; Sabit, Hemragul; Miyashita, Katsuyoshi; Hayashi, Yutaka　Brain Tumor Pathology　31　3　172-176　2014/01/01
  • 　Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival　Teng, Lei; Nakada, Mitsutoshi; Furuyama, Natsuki; Sabit, Hemragul; Furuta, Takuya; Hayashi, Yutaka; Takino, Takahisa; Dong, Yu; Sato, Hiroshi; Sai, Yoshimichi; Miyamoto, Kenichi; Berens, Michael E.; Zhao, Shiguang; Hamada, Junichiro　Neuro-Oncology　15　12　1710-1720　2013/12/01
  • 　Predictive value of fractional anisotropy of the arcuate fasciculus for the functional recovery of language after brain tumor resection: A preliminary study　Clin Neurol Neurosurg　117　45-50　2013/12
  • 　Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling　Pyko IV, Nakada M, Sabit H, Teng L, Furuyama N, Hayashi Y, Kawakami K, Minamoto T, Fedulau AS, Hamada JI　Carcinogenesis　34　2206-2217　2013/09
  • 　Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival　Teng L, Nakada M, Furuyama N, Sabit H, Furuta T, Hayashi Y, Takino T, Dong Y, Sato H, Sai Y, Miyamoto KI, Berens ME, Zhao SG, Hamada JI　Neuro-Oncology　15　1710-1720　2013/08
  • 　Progressive adult primary glioblastoma in the medulla oblongata with an unmethylated MGMT promoter and without an IDH mutation　Yoshikawa A, Nakada M, Watanabe T, Hayashi Y, Sabit H, Kato Y, Suzuki S, Ooi A, Sato H, Hamada JI　Brain Tumor Pathol　30　175-179　2013/07
  • 　Surgical strategies for nonenhancing slow-growing gliomas with special reference to functional reorganization: a review with own experience　Hayashi Y, Nakada M, Kinoshita M, Hamada JI　Neurol Med Chir (Tokyo)　53　438-446　2013/07
  • 　Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion　Nakada M, Nambu E, Furuyama N, Yoshida Y, Takino T, Hayashi Y, Sato H, Sai Y, Tsuji T, Miyamoto KI, Hirao A, Hamada JI　Br J Cancer　108　2516-2524　2013/06
  • 　Right superior longitudinal fasciculus: Implications for visuospatial neglect mimicking Gerstmann’s syndrome　Hayashi Y, Kinoshita M, Furuta T, Watanabe T, Nakada M, Hamada JI　Clinical Neurology and Neurosurgery　115　775-777　2013/06
  • 　Right superior longitudinal fasciculus: Implications for visuospatial neglect mimicking Gerstmann's syndrome　Hayashi, Yutaka; Kinoshita, Masashi; Furuta, Takuya; Watanabe, Takuya; Nakada, Mitsutoshi; Hamada, Junichiro　Clinical Neurology and Neurosurgery　115　6　775-777　2013/06/01
  • 　Molecular analysis of a recurrent glioblastoma treated with bevacizumab　Furuta T, Nakada M, Misaki K, Sato Y, Hayashi Y, Nakanuma Y, Hamada JI　Brain Tumor Pathology　2013/03
  • 　Visualization of dominant angiographical arteriovenous shunting in parasylvian glioblastomas　Yoshikawa A, Nakada M, Kita D, Watanabe T, Kinoshita M, Miyashita K, Furuta T, Hamada JI, Uchiyama N, Hayashi Y　Acta Neurochirurgica　2013/02
  • 　Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy　Kitano A, Shimasaki T, Chikano Y, Nakada M, Hirose M, Higashi T, Ishigaki Y, Endo Y, Takino T, Sato H, Sai Y, Miyamoto KI, Motoo Y, Kawakami K, Minamoto T.　PLoS One　8　e55289　2013/02
  • 　Force-detecting gripper and force feedback system for neurosurgery applications　Yoneyama T, Watanabe T, Kagawa H, Hamada JI, Hayashi Y, Nakada M　Int J Comp Assist Radiol and Surg　2013/01
  • 　Functional reorganization in the patient with progressing glioma of pure primary motor cortex: A case report with special reference to the topographic central sulcus defined by SEP.　Hayashi Y, Nakada M, Kinoshita M, Hamada JI　World Neurosurgery　2013/01
  • 　Receptor tyrosine kinases: Principles and functions in glioma invasion　Nakada, Mitsutoshi; Kita, Daisuke; Teng, Lei; Pyko, Ilya V.; Watanabe, Takuya; Hayashi, Yutaka; Hamada, Junichiro　Advances in Experimental Medicine and Biology　986　143-170　2013/01/01
  • 　Force-detecting gripper and force feedback system for neurosurgery applications　Yoneyama, Takeshi;Watanabe, Tetsuyou;Kagawa, Hiroyuki;Hamada, Junichiro;Hayashi, Yutaka;Nakada, Mitsutoshi　INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY　8　5　819-829　2013
  • 　Awake surgery with line bisection task for two cases of parietal glioma in the non-dominant hemisphere　Kitabayashi, Tomohiro; Nakada, Mitsutoshi; Kinoshita, Masashi; Sakurai, Hiroyuki; Kobayashi, Saori; Okita, Hirokazu; Nanbu, Yuko; Hayashi, Yutaka; Hamada, Junichiro　Neurological Surgery　40　12　1087-1093　2012/12/01
  • 　Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells　Jin R, Nakada M, Teng L, Furuta T, Sabit H, Hayashi Y, Demuth T, Hirao A, Sato H, Zhao G, Hamada JI　Neuroscience letters　534　316-321　2012/12
  • 　Correlation between language function and the left arcuate fasciculus detected by diffusion tensor imaging tractography after brain tumor surgery　Hayashi Y, Kinoshita M, Nakada M, Hamada JI　J Neurosurg　117　839-843　2012/11
  • 　Neuro-Sweet disease mimicking recurrent anaplastic astrocytoma associated with therapy-related myelodysplastic syndrome: a case report　Shimizu Y, Watanabe T, Nakada M, Hayashi Y, Hamaguchi Y, Sugimori N, Hamada JI　Clinical Neurology and Neurosurgery　114　1049-51　2012/09
  • 　The strategy for enhancing temozolomide against malignant glioma　Nakada M, Furuta T, Hayashi Y, Minamoto T, Hamada JI　Frontiers in Radiation Oncology　2　98　2012/08
  • 　Association between carotid plaque composition assessed by multidetector computed tomography and cerebral embolism after carotid stenting　Uchiyama N, Misaki K, Mohri M, Hirota Y, Watanabe T, Nakada M, Hayashi Y, Ueda F, Hamada JI　Neuroradiology　54　487-493　2012/05
  • 　Prediction of high-grade meningioma by preoperative MRI assessment　Kawahara Y, Nakada M, Hayashi Y, Kai Y, Hayashi Y, Uchiyama N, Nakamura H, Kuratsu JI, Hamada JI　J Neurooncol　108　147-152　2012/05
  • 　What bone-part is important to remove in accessing the suprachiasmatic region with less frontal lobe retraction in frontotemporal craniotomies　Kinoshita M, Tanaka S, Nakada M, Ozaki N, Hamada JI, Hayashi Y　World Neurosurgery　77　342-348　2012/02
  • 　Recurrent anaplastic meningioma treated by sunitinib based on the absolute quantitative proteomics　Yoshikawa A, Nakada M, Ohtsuki S, Hayashi Y, Obuchi W, Sato Y, Ikeda C, Watanabe T, Kawahara Y, Hasegawa T, Sabit H, Kita D, Hayashi Y, Nakanuma Y, Terasaki T, Hamada JI　Neuropathology and Applied Neurobiology　38　105-110　2012/02
  • 　Progressive tentorial cavernous malformation　Furuta T, Nakada M, Watanabe T, Hayashi Y, Hamada JI　Surgical Neurology International　3　18　2012/02
  • 　Association fibers connecting the Broca center and the lateral superior frontal gyrus: a microsurgical and tractographical anatomy　Kinoshita M, Shinohara H, Hori O, Ozaki N, Ueda F, Nakada M, Hamada JI, Hayashi Y　J Neurosurg　116　323-330　2012/02
  • 　Neuro-Sweet disease mimicking recurrent anaplastic astrocytoma associated with therapy-related myelodysplastic syndrome: A case report　Shimizu, Yu; Watanabe, Takuya; Nakada, Mitsutoshi; Hayashi, Yutaka; Hamaguchi, Yasuhito; Sugimori, Naomi; Hamada, Junichiro　Clinical Neurology and Neurosurgery　114　7　1049-1051　2012/09/01
  • 　Association between carotid plaque composition assessed by multidetector computed tomography and cerebral embolism after carotid stenting　Uchiyama, Naoyuki; Misaki, Kouichi; Mohri, Masanao; Watanabe, Takuya; Hirota, Yuichi; Nakada, Mitsutoshi; Hayashi, Yutaka; Ueda, Fumiaki; Hamada, Junichiro　Neuroradiology　54　5　487-493　2012/05/01
  • 　Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics　Yoshikawa, Akifumi; Nakada, Mitsutoshi; Ohtsuki, Sumio; Hayashi, Yasuhiko; Obuchi, Wataru; Sato, Yasunori; Ikeda, Chiemi; Watanabe, T.; Kawahara, Yosuke; Hasegawa, Takeshi; Sabit, Hemragul; Kita, Daisuke; Hayashi, Yutaka; Nakanuma, Yasuni; Terasaki, Tetsuya; Hamada, Junichiro　Neuropathology and Applied Neurobiology　38　1　105-110　2012/02/01
  • 　Ganglioglioma of the thoracolumbar spinal cord in a patient with neurofibromatosis type 1: A case report and literature review　Hayashi, Yutaka; Nakada, Mitsutoshi; Mohri, Masanao; Murakami, Hideki; Kawahara, Norio; Hamada, Junichiro　Pediatric Neurosurgery　47　3　210-213　2012/01/01
  • 　Role of Eph/ephrin tyrosine kinase in malignant glioma　Nakada, Mitsutoshi; Hayashi, Yutaka; Hamada, Junichiro　Neuro-Oncology　13　11　1163-1170　2011/11/01
  • 　Aberrant signaling pathways in Glioma　Nakada, Mitsutoshi; Kita, Daisuke; Watanabe, Takuya; Hayashi, Yutaka; Teng, Lei; Pyko, Ilya V.; Hamada, Junichiro　Cancers　3　3　3242-3278　2011/09/01
  • 　MGMT promoter methylation and temozolomide response in choroid plexus carcinoma　Misaki, Kouichi; Nakada, Mitsutoshi; Mohri, Masanao; Hayashi, Yutaka; Hamada, Junichiro　Brain Tumor Pathology　28　3　259-263　2011/07/01
  • 　Role of Eph/ephrin tyrosine kinase in malignant glioma　Nakada M, Hayashi Y, Hamada JI　Neuro-Oncology　13　1163-1170　2011/11
  • 　Ganglioglioma of the thoracolumbar spinal cord in a patient with neurofibromatosis type 1: a case report and literature review　Hayashi Y, Nakada M, Mohri M, Murakami H, Kawahara N, Hamada JI　Pediatr Neurosurg　47　210-213　2011/10
  • 　MGMT promoter methylation and temozolomide response in choroid plexus carcinoma　Misaki K, Nakada M, Mohri M, Hayashi Y, Hamada JI　Brain Tumor Pathol　28　259-63　2011/07
  • 　Secondary anaplastic astrocytoma developing in a young adult with autoimmune lymphoproliferative syndrome (ALPS)　Kita D, Hayashi Y, Watanabe T, Korshunov A, von Deimling A, Nakada M, Kinoshita M, Uchiyama N, Kasahara Y, Zen Y, Hamada JI, Hayashi Y　Neuropathology and Applied Neurobiology　37　423-427　2011/06
  • 　Anaplastic meningioma with extremely rapid recurrence　Kawahara Y, Nakada M, Hayashi Y, Watanabe T, Tamase A, Hayashi Y, Uchiyama N, Nitta H, Hamada JI　Neurol Med Chir (Tokyo)　51　386-388　2011/05
  • 　Ependymoma and choroid plexus papilloma as synchronous multiple neuroepithelial tumors in the same patient: a case report and review of literature　Hayashi Y, Mohri M, Nakada M, Hamada JI　Neurosurgery　68　E1144-1147　2011/04
  • 　Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy　Teng L, Nakada M, Zhao SG, Endo Y, Furuyama N, Nambu E, Pyko IV, Hayashi Y, Hamada JI　Br J Cancer　104　798-807　2011/03
  • 　Transcrusal approach to the retrochiasmatic region with special reference to temporal lobe retraction: An anatomical study.　Kinoshita M, Nakada M, Tanaka S, Ozaki N, Hamada JI, Hayashi Y　Acta Neurochirurgica　153　659-665　2011/03
  • 　The correlation between promoter methylation status and the expression level of O6-methylguanine-DNA methyltransferase in recurrent glioma　Suzuki T, Nakada M, Yoshida Y, Nambu E, Furuyama N, Kita D, Hayashi Y, Hayashi Y, Hamada JI　Jpn J Clin Oncol　41　190-196　2011/02
  • 　NKX2.2 suppresses self-renewal of glioma-initiating cells　Muraguchi T, Tanaka S, Yamada D, Tamase A, Nakada M, Nakamura H, Hoshii T, Ooshio T, Tadokoro Y, Naka K, Ino Y, Todo T, Kuratsu JI, Saya H, Hamada JI, Hirao A　Can Res　71　1135-1145　2011/02
  • 　Epithelioid glioblastoma changed to typical glioblastoma: the methylation status of MGMT promoter and 5-ALA fluorescence　Tanaka S, Nakada M, Hayashi Y, Nakada S, Kitamura-Sawada S, Furuyama N, Suzuki T, Kamide T, Hayashi Y, Yano S, Hamada JI　Brain Tumor Pathol　28　59-64　2011/02
  • 　Aberrant signaling pathways in glioma　Nakada M, Kita D, Watanabe T, Hayashi Y, Teng L, Pyko IV, Hamada JI　Cancers　3　3242-3278　2011/01
  • 　Force detecting gripper and flexible micro manipulator for neurosurgery　Yoneyama T, Watanabe T, Kagawa H, Hamada JI, Hayashi Y, Nakada M.　Conf Proc IEEE Eng Med Biol Soc　2011　6695-6699　2011/01
  • 　Ependymoma and Choroid Plexus Papilloma as Synchronous Multiple Neuroepithelial Tumors in the Same Patient: A Case Report and Review of Literature　Hayashi, Yutaka;Mohri, Masanao;Nakada, Mitsutoshi;Hamada, Jun-ichiro　NEUROSURGERY　68　4　E1144-E1147　2011
  • 　NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells　Muraguchi, Teruyuki;Tanaka, Shingo;Yamada, Daisuke;Tamase, Akira;Nakada, Mitsutoshi;Nakamura, Hideo;Hoshii, Takayuki;Ooshio, Takako;Tadokoro, Yuko;Naka, Kazuhito;Ino, Yasushi;Todo, Tomoki;Kuratsu, Jun-ichi;Saya, Hideyuki;Hamada, Jun-ichiro;Hirao, Atsushi　CANCER RESEARCH　71　3　1135-1145　2011
  • 　Transcrusal approach to the retrochiasmatic region with special reference to temporal lobe retraction: an anatomical study　Kinoshita, Masashi;Nakada, Mitsutoshi;Tanaka, Shingo;Ozaki, Noriyuki;Hamada, Jun-ichiro;Hayashi, Yutaka　ACTA NEUROCHIRURGICA　153　3　659-665　2011
  • 　The Correlation between Promoter Methylation Status and the Expression Level of O-6-Methylguanine-DNA Methyltransferase in Recurrent Glioma　Suzuki, Tomohide;Nakada, Mitsutoshi;Yoshida, Yuya;Nambu, Emi;Furuyama, Natsuki;Kita, Daisuke;Hayashi, Yutaka;Hayashi, Yasuhiko;Hamada, Jun-ichiro　JAPANESE JOURNAL OF CLINICAL ONCOLOGY　41　2　190-196　2011
  • 　Anaplastic Meningioma With Extremely Rapid Recurrence-Case Report　Kawahara, Yosuke;Nakada, Mitsutoshi;Hayashi, Yutaka;Watanabe, Takuya;Tamase, Akira;Hayashi, Yasuhiko;Uchiyama, Naoyuki;Nitta, Hisashi;Hamada, Jun-ichiro　NEUROLOGIA MEDICO-CHIRURGICA　51　5　386-388　2011
  • 　Radiation induced cerebellar high grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report　Kamide T, Nakada M, Hayashi Y, Suzuki T, Hayashi Y, Uchiyama N, Kijima T, Hamada JI　J Neurooncol　100　299-303　2010/11
  • 　PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas　Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC　Genes & Development　24　2205-2218　2010/10
  • 　A case of neurosarcoidosis with necrotizing granuloma expressing angiotensin converting enzyme　Kitajima S, Sakai N, Furuichi K, Tomokage M, Hara A, Kitagawa K, Sawada S, Zen Y, Nakada M, Kaneko S, Wada T　Mod Rheumatol　20　506-510　2010/10
  • 　Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with survival of patients with glioblastoma.　Yoshida Y, Nakada M, Sugimoto N, Harada T, Hayashi Y, Kita D, Uchiyama N, Hayashi Y, Yachie Y, Takuwa Y, Hamada JI.　INTERNATIONAL JOURNAL OF CANCER　98　2341-2352　2010/05
  • 　The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion　Nakada M, Anderson EM, Demuth T, Nakada S, Reavie LB, Drake KL, Hoelzinger DB, Berens ME.　INTERNATIONAL JOURNAL OF CANCER　126　1155-1165　2010/05
  • 　Implication of 5-ALA fluorescence of the ventricle wall for postoperative communicating hydrocephalus associated with CSF dissemination in glioblastoma patients - A report of seven cases-　Hayashi Y*, Nakada M*, Tanaka S, Uchiyama N, Hayashi Y, Kita D, Hamada JI　J Neurosurg　112　1015-1019　2010/05
  • 　The expression level of sphingosine-1-phosphate receptor type 1 is related to MIB-1 labeling index and predicts survival of glioblastoma patients　Yoshida Y, Nakada M, Harada T, Tanaka S, Furuta T, Hayashi Y, Kita D, Uchiyama N, Hayashi Y, Hamada JI　J Neurooncol　98　41-47　2010/05
  • 　Retro-odontoid pseudotumor without atlantoaxial subluxation　Tanaka S, Nakada M, Hayashi Y, Mohri M, Hayashi Y, Uchiyama N, Hamada JI　J Clin Neurosci　17　649-652　2010/05
  • 　Skull osteohypertrophy as a complication of bone wax　Kamide T, Nakada M, Hirota Y, Hayashi Y, Hayashi Y, Uchiyama N, Hamada JI　J Clin Neurosci　16　1658-1660　2009/12
  • 　An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3b　Miyashita K, Nakada M, Shakoori A, Ishigaki Y, Shimasaki T, Motoo Y, Kawakami K, Minamoto T　Anti-Cancer Agents in Medicinal Chemistry　9　1114-1122　2009/12
  • 　Intraparenchymal pneumocephalus caused by ethmoid sinus osteoma　Kamide T, Nakada M, Hayashi Y, Hayashi Y, Uchiyama N, Hamada JI　J Clin Neurosci　16　1487-1489　2009/11
  • 　Mollaret’s meningitis associated with occipital dermal sinus　Shimizu M, Araki R, Niida Y, Nakada M, Yachie A, Kamide T, Yokoyama T, Iwasa T　Journal of Pediatrics　155　757　2009/11
  • 　Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin　Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada JI, Hirao A.　PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME　106　40　17163-17168　2009/09
  • 　Ossified peripheral middle cerebral artery aneurysm in a 30-year-old man　Hayashi Y, Shima H, Kinoshita M, Nakada M, Miyashita K, Hamada JI　J Clin Neurosci　16　1075-1077　2009/08
  • 　Role of Rac1-regulated signaling in medulloblastoma invasion　Zavarella S, Nakada M, Belverud S, Coniglio SJ, Chan A, Mittler MA, Schneider SJ, Symons M.　Journal of Neurosurg: Pediatrics　4　2　 97-104　2009/08
  • 　BCL10 single nucleotide polymorphism and its association with CSF dissemination of　primary intracranial germ cell tumors　Hayashi Y, Watanabe T, Nakada M, Kita D, Hayashi Y, Uchiyama N, Hamada JI　Pediatr Neurosurg　45　291-295　2009/04
  • 　Potential effect of glycogen synthase kinase 3 beta inhibition against human glioblastoma　Miyashita K, Kawakami K, Nakada M, Mai W, Shakoori A, Fujisawa H, Hayashi Y, Hamada JI, MinamotoT.　CLINICAL CANCER RESEARCH　15　3　887-897　2009/02
  • 　Gonadotropin-releasing hormone (GnRH) and its receptor in human meningiomas　Hirota Y, Tachibana O, Uchiyama N, Hayashi Y, Nakada M, Kita D, Watanabe T, Higashi R, Hamada JI, Hayashi Y　Clinical Neurol and Neurosurg　45　291-295　2009/02
  • 　A reevaluation of the primary diagnosis of hemangiopericytoma and the clinical importance of differential diagnosis from solitary fibrous tumor of the central nervous system　Clinical Neurol and Neurosurg　111　34-38　2009/01
  • 　The guanine nucleotide exchange factors Trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma　Salhia B, Tran NL, Chan A, Wolf A, Nakada M, Ennis M, Rutka F, McDonough WS, Berens ME, Symons M, Rutka JT　Am J Pathol　173　1828-1838　2008/12
  • 　Unusual angiographic changes in an internal carotid artery pseudoaneurysm after infection in the deep neck space　Hayashi Y, Shima H, Miyashita K, Kinoshita M, Nakada M, Kida S, Hamada JI.　NEUROLOGIA MEDICO-CHIRURGICA　48　5　216-9　2008/05
  • 　Role of myosin II activity and the regulation of myosin light chain phosphorylation in astrocytomas.　65　1212-1222　2008
  • 　Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion.　JOURNAL OF NEURO-ONCOLOGY　86　 297-309　2008
  • 　Glioma cells on the run, the migratory transcriptome of 10 human glioma cell lines.　BMC Genomics　9　 54　2008
  • 　Molecular targets of glioma invasion.　Nakada M, Nakada S, Demuth T, Tran NL, Hoelzinger DB, Berens ME　64　4　458-478　2007/02
  • 　MAP-ing glioma invasion-MKK3 and p38 drive glioma invasion and progression and predict survival.　6　1212-1222　2007
  • 　Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.　Nakada M, Drake KL, Nakada S, Niska JA, Berens ME　CANCER RESEARCH　66　 8492-8500　2006/09
  • 　Increased Fn14 expression levels promote glioma cell invasion via Rac1 and NF-kappa B and correlate with poor patient outcome.　66　208-215　2006
  • 　EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion.　AMERICAN JOURNAL OF PATHOLOGY　167　 565-576　2005/08
  • 　Human glioblastomas overexpress ADAMTS-5 that degrades brevican.　ACTA NEUROPATHOLOGICA　110　 239-246　2005
  • 　Cell migration and invasion assays.　METHODS　37　 208-215　2005
  • 　JSAP1/JIP3 cooperates with FAK to regulate c-Jun N-terminal kinase and cell migration.　JOURNAL OF BIOLOGICAL CHEMISTRY　280　 37772-37781　2005
  • 　Inhibition of Rho-Kinase effects astrocytoma morphology, motility and invasion through activation of Rac1.　CANCER RESEARCH　65　 8792-8800　2005
  • 　Role of synaptojanin 2 in glioma cell migration and invasion.　CANCER RESEARCH　64　8271-8275　2004/12
  • 　ADAM12 is selectively overexpressed in human glioblastoma and is associated with glioblastoma cell proliferation and shedding HB-EGF.　AMERICAN JOURNAL OF PATHOLOGY　165　1743-1753　2004/11
  • 　The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells.　CANCER RESEARCH　64　 3179-3185　2004/07
  • 　Recurrent intracranial esthesioneuroblastoma outside the initial field of radiation with progressive dural and intra-orbital invasion.　ACTA NEUROCHIRURGICA　146　179-182　2004/05
  • 　Simulation of clipping position for cerebral aneurysms using three-dimensional computed tomography angiography.　NEUROLOGIA MEDICO-CHIRURGICA　44　6-13　2004/01
  • 　Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins.　CANCER RESEARCH　63　3364-3369　2003/06
  • 　CrkI adaptor protein modulates cell migration and invasion in glioblastoma.　CANCER RESEARCH　63　2335-2337　2003/05
  • 　Suppression of MT1-MMP-mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product N-Tes.　CANCER RESEARCH　61　8896-8902　2001/12
  • 　Expression of dominant negative form of Ets-1 suppresses fibronectin-stimulated cell adhesion and migration through down-regulation of integrin α5 expression in U251 glioma cell line　Cancer Res　61　21　7985-7991　2001/11
  • 　Contrast-enhanced fluid-attenuated inversion-recovery MRI is useful to detect the CSF dissemination of glioblastoma　J Comput Assist Tomogr　25　6　953-956　2001/11
  • 　Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma　J Neurosurg　94　3　464-73　2001/03
  • 　Rupture of an aneurysm during three-dimensional computerized tomography angiography　J Neurosurg　93　5　900　2000/11
  • 　MRI findings of cerebral paragonimiasis in chronic stage　Clin Radiol　54　9　622-624　1999/09
  • 　Ets-1 positively regulates expression of urokinase-type plasminogen activator (uPA) and invasiveness of astrocytic tumors　J Neuropathol Exp Neurol　58　4　329-334　1999/04
  • 　Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors　Am J Pathol　154　2　417-428　1999/02
  • 　Sweet's syndrome associated with granulocyte colony-stimulating factor　Eur J Dermatol　8　7　503-505　1998/10
  • 　The cluster of arachnoid diverticula in the occipital bone: report of two cases with literature review　Acta Neurochir(Wien)　140　7　647-650　1998/07
  • 　Contrast-enhanced MRI of intracellar arachnoid cyst: relationship between the pituitary gland and cyst.　NEURORADIOLOGY　38　566-568　1996/08
  • 　Retrospective Observational Study of Patients With Subdural Hematoma Treated With Idarucizumab　Suehiro E, Ishihara H, Kogeichi Y, Ozawa T, Haraguchi K, Honda M, Honda Y, Inaba M, Kabeya R, Kanda N, Koketsu K, Murakami N, Nakamoto H, Oshio K, Saigusa K, Shuto T, Sugiyama S, Suzuyama K, Terashima T, Tsuura M, Nakada M, Kobata H, Higashi T, Sakai N, Suzuki M　Neurotrauma Rep 　4　790-796　2023
  • 　Distinct subdivisions of subcortical U-fiber regions in the gyrencephalic ferret brain　Yoshino M, Shiraishi Y, Saito K, Kameya N, Hamabe-Horiike T, Shinmyo Y, Nakada M, Ozaki N, Kawasaki H　Neurosci Res 　S0168-0102(23)00194-3, 　2023
  • 　Epidemiological and therapeutic profiles of lung cancer patients in the Hokushin Region Japan: a retrospective hospital administrative database study　Kobayashi T, Nishino Y, Takiguchi T, Kanda S, Otsuki K, Tanaka Y, Nakazawa Y, Ito KI, Hayashi R, Yasumoto K, Uramoto H, Hirono Y, Makino T, Nakada M, Yano S, Koizumi T　BMC Pulm Med 　23　322　2023
  • 　Nuclear transport surveillance of p53 by nuclear pores in glioblastoma　Ikliptikawati DK, Hirai N, Makiyama K, Sabit H, Kinoshita M, Matsumoto K, Lim K, Meguro-Horike M, Horike SI, Hazawa M, Nakada M, Wong RW　Cell Rep 　42　112882　2023
  • 　Safety and efficacy of the endoscopic transsphenoidal transclival approach performed using direct cortical stimulation for pontine cavernous malformations　Takeuchi K, Nagata Y, Sasagawa Y, Ito E, Yamamoto T, Mizuno A, Sasaki H, Kondo T, Araki Y, Nakada M, Saito R　J Neurosurg 　1-9　2023
  • 　Association Between Risperidone Use and Kidney Function Decline in Patients with Schizophrenia: A Retrospective Cohort Study　Oshima M, Toyama T, Nakade Y, Yomogida D, Yuasa T, Horikoshi K, Minami T, Ogura H, Nakagawa S, Miyagawa T, Kitajima S, Hara A, Sakai N, Shimizu M, Mita M, Kinoshita M, Nakada M, Kikuchi M, Iwata Y, Wada T　Clin Ther. 　45　889-893　2023
  • 　Patterns of failure in glioblastoma multiforme following Standard (60 Gy) or Short course (40 Gy) radiation and concurrent temozolomide　Mizuhata M, Takamatsu S, Shibata S, Sakurai T, Minamikawa R, Yamazaki M, Kinoshita M, Miyashita K, Kumano T, Nakada M, Gabata T　Jpn J Radiol 　41　660-668　2023
  • 　The effect of damage to the white matter network and premorbid intellectual ability on postoperative verbal short-term memory and functional outcome in patients with brain lesions　Ebina K, Matsui M, Kinoshita M, Saito D, Nakada M　PLoS One 　18　e0280580　2023
  • 　Epidemiological and Therapeutic Analyses in Lung Cancer Patients Over 80 Years Old in the Hokushin Region: A Retrospective Hospital Administrative Database Study　Koizumi T, Nishino Y, Takiguchi T, Kanda S, Otsuki K, Tanaka Y, Tomita R, Araki T, Hayashi R, Yasumoto K, Uramoto H, Hirono Y, Makino T, Nakada M, Yano S　Clin Lung Cancer 　24　145-152　2023
  • 　Intra-Brain and Plasma Levels of L-Serine Are Associated with Cognitive Status in Patients with Chronic Kidney Disease　Iwata Y, Nakade Y, Kinoshita M, Sabit H, Nakajima R, Furuichi K, Mita M, Nakane M, Sakai N, Kitajima S, Toyama T, Miyagawa T, Hara A, Shimizu M, Sato K, Oshima M, Nakagawa S, Yamamura Y, Ogura H, Koshino Y, Nakada M, Wada T　Kidney Dis (Basel) 　9　118-129　2023
  • 　Mentalizing can be impaired in patients with meningiomas originating in the anterior skull base　Demura M, Nakajima R, Tanaka S, Kinoshita M, Nakada M　World Neurosurg 　S1878-8750(23)01790-4, 　2023
  • 　Periprocedural antiplatelet medication assessed by VerifyNow for neuroendovascular treatment: Comparison of prasugrel with clopidogrel　Nambu K, Misaki K, Uno T, Tsutsui T, Kamide T, Nakada M　Interv Neuroradiol 　15910199231219019, 　2023
  • 　Recurrence of an extracranial internal carotid artery aneurysm treated with STA-MCA bypass and trapping due to neovascularization from an ascending pharyngeal artery: illustrative case　Shomura K, Kamide T, Uno T, Misaki K, Nakada S, Ito Y, Sabit H, Yoshikawa A, Mohri M, Uchiyama N, Nakada M　J Neurosurg Case Lessons 　7　 CASE23617 　2024
  • 　Glioblastomas at the white matter of temporo-parietal junction cause a poor postoperative independence level　Nakajima R, Kinoshita M, Okita H, Nakada M　J Neurooncol 　165　191-199　2023
  • 　Carotid artery stenting after balloon aortic valvuloplasty in cervical internal carotid artery stenosis associated with severe aortic stenosis: A case report　Kitabayashi T, Misaki K, Kamide T, Nakada M　Neurol Clin Neurosci 　11　319-321　2023/10
  • 　α-SMA positive vascular mural cells suppress cyst formation in hemangioblastoma　Sakaguchi M, Nakajima R, Ichinose T, Tanaka S, Kimura R, Sabit H, Nakada S, Nakada M　Brain Tumor Pathol 　40　176-184　2023
  • 　Sympathetic Nervous Hyperactivity Impairs Microcirculation Leading to Early Brain Injury After Subarachnoid Hemorrhage　Demura M, Ishii H, Takarada-Iemata M, Kamide T, Yoshikawa A, Nakada M, Hori O　Stroke 　54　1645-1655　2023
  • 　Therapeutic potential of pentamidine for glioma-initiating cells and glioma cells through multimodal antitumor effects　Tamai S, Ichinose T, Jiapaer S, Hirai N, Sabit H, Tanaka S, Kinoshita M, Kobayashi M, Hirao A, Nakada M　Cancer Sci 　114　2920-2930　2023
  • 　Optical coherence tomography detects early optic nerve damage before visual field defect in patients with pituitary tumors　Sasagawa Y, Nakahara M, Takemoto D, Nakada M　Neurosurg Rev 　46　85　2023
  • 　Targeted transvenous embolization of a dural arteriovenous fistula at the jugular tubercle venous complex　Tsutsui T, Misaki K, Yoshikawa A, Nogami K, Nambu I, Kamide T, Muramatsu N, Nakada M　Surg Neurol Int 　14　44　2023
  • 　The first coil embolization ratio is the key factor for retreatment for unruptured cerebral aneurysms　Nogami K, Misaki K, Tsutsui T, Nambu I, Kamide T, Nakada M　Surg Neurol Int. 　14　53　2023
  • 　Evaluation of a scoring system to assess proficiency in cerebral angiography for neuroendovascular surgery education　Misaki K, Kamide T, Uno T, Tsutsui T, Nambu I, Nakada M　Heliyon 　9　e13249　2023
  • 　Partially thrombosed distal posterior cerebral artery aneurysm treated with surgical trapping through occipital transtentorial approach assisted by endovascular coil embolization　Nambu K, Kamide T, Tsutsui T, Kitabayashi T, Yoshikawa A, Misaki K, Nakada M　Surg Neurol Int 　14　20　2023
  • 　Factors related to high bifurcation level of common femoral artery　Uno T, Misaki K, Nakajima R, Nambu I, Yoshikawa A, Kamide T, Nakada M　J Stroke Cerebrovasc Dis 　32　106976　2023
  • 　Rapid Conversion from Solitary Plasmacytoma with Minimal Skull Marrow Involvement to Symptomatic Multiple Myeloma: a Case Report　Kawahara Y, Kinoshita M, Ohata K, Tamai S, Miyashita, K, Nakada M　SN Comprehensive Clinical Medicine　 5　46　2023
  • 　Liquid biomarkers in glioma　10. Tamai S, Ichinose T, Nakada M　Brain Tumor Pathol 　40　66-77　2023
  • 　脳外科手術における視空間認知機能の温存法　中田光俊　Clinical Neuroscience　40　108-110　2022
  • 　SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.　Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.　Commun Biol　5　22　2022
  • 　Two different subcortical language networks supporting distinct Japanese orthographies: morphograms and phonograms.　Tamai S, Kinoshita M, Nakajima R, Okita H, Nakada M.　Brain Struct Funct.　2022
  • 　Late complications of visual impairment and hydrocephalus after flow diverter-assisted coil embolisation for intracranial large aneurysm: a case report and literature review.　Ichinose T, Misaki K, Uchiyama N, Kamide T, Nambu I, Yoshikawa A, Tsuchiya S, Nakada M.　Br J Neurosurg.　2022
  • 　脳神経外科医が挑む脳科学　中田光俊　神経科学研究所医誌　6　3-7　2021
  • 　左下頭頂小葉腫瘍に対する摘出術後に相貌変形視を呈した左利きの1例　沖田浩一、福永真哉、中嶋理帆、木下雅史、中田光俊、八幡徹太郎　高次脳機能研究　41　368-376　2021
  • 　Morphological factors affecting vortex core instability on 4D flow MRI of unruptured cerebral aneurysms.　Futami K, Misaki K, Uno T, Nambu I, Kamide T, Nakada M.　Neurol Res　2021
  • 　Cancer among children, adolescents and young adults in the Hokushin region, Japan, between 2010 and 2015.　Okura E, Nishino Y, Sakashita K, Tanimoto A, Hayashi R, Yoshida Y, Nakada M, Koizumi T, Yano S, Nakazawa Y.　Jpn J Clin Oncol. 　2021
  • 　Efficacy and safety of nivolumab in Japanese patients with first recurrence of glioblastoma: an open-label, non-comparative study.　Aoki T, Kagawa N, Sugiyama K, Wakabayashi T, Arakawa Y, Yamaguchi S, Tanaka S, Ishikawa E, Muragaki Y, Nagane M, Nakada M, Suehiro S, Hata N, Kuroda J, Narita Y, Sonoda Y, Iwadate Y, Natsumeda M, Nakazato Y, Minami H, Hirata Y, Hagihara S, Nishikawa R.　Int J Clin Oncol. 　26　2205-2215　2021
  • 　Low tumor cell content predicts favorable prognosis in germinoma patients.　Takami H, Satomi K, Fukuoka K, Fukushima S, Matsushita Y, Yamasaki K, Nakamura T, Tanaka S, Mukasa A, Saito N, Suzuki T, Yanagisawa T, Nakamura H, Sugiyama K, Tamura K, Maehara T, Nakada M, Nonaka M, Asai A, Yokogami K, Takeshima H, Iuchi T, Kanemura Y, Kobayashi K, Nagane M, Kurozumi K, Yoshimoto K, Matsuda M, Matsumura A, Hirose Y, Tokuyama T, Kumabe T, Narita Y, Shibui S, Nakazato Y, Nishikawa R, Matsutani M, Ichimura K.　Neurooncol Adv　3　2021
  • 　Mathematical modeling and mutational analysis reveal optimal therapy to prevent malignant transformation in grade II IDH-mutant gliomas.　Aoki K, Suzuki H, Yamamoto T, Yamamoto KN, Maeda S, Okuno Y, Ranjit M, Motomura K, Ohka F, Tanahashi K, Hirano M, Nishikawa T, Shimizu H, Kitano Y, Yamaguchi J, Yamazaki S, Nakamura H, Takahashi M, Narita Y, Nakada M, Deguchi S, Mizoguchi M, Momii Y, Muragaki Y, Abe T, Akimoto J, Wakabayashi T, Saito R, Ogawa S, Haeno H, Natsume A.　Cancer Res　81　4861-4873　2021
  • 　Multi-institutional survey of malignant pleural mesothelioma patients in the Hokushin region.　Uramoto H, Takiguchi T, Koizumi T, Tanimoto A, Hayashi R, Nakazawa Y, Ito KI, Nakada M, Hirono Y, Nishino Y, Yano S.　J Cancer Res Clin Oncol. 　2021
  • 　Necessity for craniospinal irradiation of germinoma with positive cytology but without spinal lesion on MR imaging - A controversy Neuro-Oncology Advances　19. Kanamori M, Takami H, Suzuki T, Tominaga T, Kurihara J, Tanaka S, Hatazaki S, Nagane M, Matsuda M, Yoshino A, Natsumeda M, Yamaoka M, Kagawa N, Akiyama Y, Fukai J, Negoto T, Shibahara I, Tanaka K, Inoue A, Mase M, Tomita T, Kuga D, Kijima N, Fukami T, Nakahara Y, Natsume A, Yoshimoto K, Keino D, Tokuyama T, Asano K, Ujifuku K, Abe H, Nakada M, Matsuda KI, Arakawa Y, Ikeda N, Narita Y, Shinojima N, Kambe A, Nonaka M, Izumoto S, Kawanishi Y, Kanaya K, Nomura S, Nakajima K, Yamamoto S, Terashima K, Ichimura K, Nishikawa R　Neurooncol Adv　3　2021
  • 　Late-onset acute disseminated encephalomyelitis followed by optic neuritis without anti-myelin oligodendrocyte glycoprotein antibodies: a biopsied case report　Mori M, Sakai K, Tada Y, Nozaki I, Usui Y, Ichinose T, Tanaka S, Takahashi T, Nakada M, Yamada M.　Neurol Sci　42　4731-4735　2021
  • 　Quality of life following awake surgery depends on ability of executive function, verbal fluency, and movement.　Nakajima R, Kinoshita M, Okita H, Nakada M　J Neurooncol　156　173-183　2021
  • 　Simultaneous Damage of the Cingulate Cortex Zone II and Fronto-Striatal Circuit Causes Prolonged Selective Attentional Deficits.　Nakajima R, Kinoshita M, Nakada M　Front Hum Neurosci　15　762578　2021
  • 　Limb-shaking syndrome derived from the contralateral hemisphere following unilateral revascularisation for moyamoya disease.　Demura, Demura M, Oishi M, Uchiyama N, Mohri M, Miyashita K, Nakada M.　Surg Neurol Int　12　579　2021
  • 　A Fiber Dissection Study of the Anterior Commissure: Correlations with Diffusion Spectrum Imaging Tractography and Clinical Relevance in Gliomas.　Liu X, Kinoshita M, Shinohara H, Hori O, Ozaki N, Nakada M.　Brain Topogr.　2021
  • 　Hemodynamic factor evaluation using computational fluid dynamics analysis for de novo bleb formation in unruptured intracranial aneurysms.　Uno T, Misaki K, Futami K, Nambu I, Yoshikawa A, Kamide T, Uchiyama N, Nakada M.　Neurol Sci　2021
  • 　Ocular ischemic syndrome due to severe internal carotid artery stenosis improved by intracranial stent placement: A case report.　Uchida W, Kamide T, Uno T, Yoshikawa A, Misaki K, Nakada M　Surg Neurol Int　12　294　2021
  • 　Thyrotropin-secreting pituitary adenomas induce left atrial enlargement with subclinical atrial fibrillation: an echocardiographic study.　Yoshiki K, Sasagawa Y, Shimojima M, Takeshita Y, Takata S, Hayashi Y, Takamura T, Tachibana O, Nakada M　Pituitary　24　778-786　2021
  • 　Disconnection of posterior part of the frontal aslant tract causes acute phase motor functional deficit.　Nakajima R, Kinoshita M, Okita H, Shinohara H, Nakada M　Brain Cogn　151　105752　2021
  • 　Direct evidence of the relationship between brain metastatic adenocarcinoma and white matter fibers: a fiber dissection and diffusion tensor imaging tractography study　Liu X, Kinoshita M, Shinohara H, Hori O, Ozaki N, Hatta T, Honma S, Nakada M.　J Clin Neurosci 　77　55-61　2020/05/11
  • 　Osimertinib overcomes alectinib resistance caused by amphiregulin in a leptomeningeal carcinomatosis model of ALK-rearranged lung cancer.　Arai S, Takeuchi S, Fukuda K, Taniguchi H, Nishiyama A, Tanimoto A, Satouchi M, Yamashita K, Ohtsubo K, Nanjo S, Kumagai T, Katayama R, Nishio M, Zheng MM, Wu YL, Nishihara H, Yamamoto T, Nakada M, Yano S.　J Thorac Oncol 　15　752-765　2020/01/21
  • 　Potential therapeutic effect of targeting glycogen synthase kinase 3β in esophageal squamous cell carcinoma.　Bolidong D, Domoto T, Uehara M, Sabit H, Okumura T, Endo Y, Nakada M, Ninomiya I, Miyashita T, Wong RW, Minamoto T.　Sci Rep　10　11807　2020
  • 　Effect of neck size on the inflow magnitude evaluated on 4D flow MRI in unruptured internal carotid artery aneurysms　Futami K, Misaki K, Uno T, Kamide T, Nakada M.　J Stroke Cerebrovasc Dis　29　105116　2020/01/11
  • 　Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.　Dewi FRP, Jiapaer S, Kobayashi A, Hazawa M, Ikliptikawati DK, Hartono, Sabit H, Nakada M, Wong RW.　Autophagy 　1-12　2020/03/24
  • 　PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma.　Furuse M, Kuwabara H, Ikeda N, Hattori Y, Ichikawa T, Kagawa N, Kikuta K, Tamai S, Nakada M, Wakabayashi T, Wanibuchi M, Kuroiwa T, Hirose Y, Miyatake SI. 　BMC Cancer　20　277　2020
  • 　Laminin subunit alpha-4 and osteopontin are glioblastoma-selective secreted proteins that are increased in the cerebrospinal fluid of glioblastoma patients 　Kohata T, ItoS, Masuda T, Furuta T, Nakada M, Ohtsuki S　J Proteome Res　19　3542-3553　2020/07/06
  • 　The guanine nucleotide exchange factor, LARG, and RhoC play a role in glioblastoma cell invasion and resistance.　Ding Z, Dong Z, Yang Y, Fortin-Ensign SP, Sabit H, Nakada M, Ruggieri R, Kloss JM, Symons M, Tran NL, Loftus JC.　Am J Pathol　190　2165-2176　2020/07/18
  • 　Glioma stem-like cells can be targeted in boron neutron capture therapy with boronophenylalanine　Kondo N, Hikida M, Nakada M, Sakurai Y, Hirata E, Takeno S, Suzuki M. 　Cancers (Basel)　12　3040　2020
  • 　Intra-aneurysmal embolization of cellulose porous beads to regenerate vessel wall: an experimental study.　Hasegawa T, Uchiyama N, Sano H, Kawahara Y, Nakada M.　Neuroradiology 　62　1169-1175　2020/05/01
  • 　Multi-institutional survey of cancer disparities in disabled patients in the region of northwestern Japan.　Sato S, Tanimoto A, Yanagimura N, Suzuki C, Takumi Y, Nishiyama A, Yamashita K, Takeuchi S, Ohtsubo K, Makino T, Yoshida Y, Hirono Y, Hayashi R, Koizumi T, Nakazawa Y, Ito KI, Motoo Y, Uramoto H, Nakada M, Nishino Y, Yano S.　Int J Clin Oncol. 　2021
  • 　Multi-institutional survey of thymic carcinoma patients in Hokushin region　Uramoto H, Takiguchi T, Koizumi T, Tanimoto A, Hayashi R, Nakazawa Y, Ito KI, Nakada M, Hirono Y, Nishino Y, Yano S　2021
  • 　Extracranial-intracranial high flow bypass as a rescue therapy for incomplete cerebral aneurysm occlusion after flow diversion: a case report.　Kamide T, Misaki K, Uno T, Yoshikawa A, Uchiyama N, Nakada M.　12　57　2021
  • 　Awake surgery for right frontal lobe glioma can preserve visuospatial cognition and spatial working memory.　Nakada M, Nakajima R, Okita H, Nakade Y, Yuno T, Tanaka S, Kinoshita M.　J Neurooncol 　2020/11
  • 　Usefulness of 2D-perfusion analysis for the assessment of unilateral cervical internal carotid artery stenosis 　Yoshikawa A, Uno T, Nambu I, Kamide T, Misaki K, Nakada M　JNET　2020
  • 　Glioma-derived extracellular vesicles promote tumor progression by conveying WT1　Tsutsui T, Kawahara H, Kimura R, Dong Y, Jiapaer S, Sabit H, Zhang J, Yoshida T, Nakada M, Hanayama R.　Carcinogenesis　41　1238-1245　2020/05/28
  • 　Prediction of internal carotid artery aneurysm recurrence by pressure difference at the coil mass surface.　Uno T, Misaki K, Nambu I, Yoshikawa A, Kamide T, Uchiyama N, Nakada M.　Neuroradiology　2020/09/14
  • 　Morphological characteristics of infected subdural hematoma: Comparison with images of chronic subdural hematoma.　Tamai S, Watanabe T, Ichinose T, Murakami KI, Ueno M, Munemoto S, Nakada M, Hayashi Y.　Clin Neurol Neurosurg 　194　105831　2020/08/08
  • 　Superficial siderosis associated with long-term recurrence of pilocytic astrocytoma in an elderly person.　Yoshiki K, Sasagawa Y, Kinoshita M, Furuta T, Tamai S, Sabit H, Tanaka S, Nakada M.　World Neurosurg 　138　541-544　2020/03/27
  • 　Progressively Enlarged Convexity Arachnoid Cysts in Elderly Patients: A Report of 2 Cases. 　Kimura R, Hayashi Y, Sasagawa Y, Kobayashi M, Oishi M, Kinoshita M, Nakada M.　World Neurosurg　135　253-358　2020
  • 　Cavernous sinus dural arteriovenous fistula with an enhanced lesion in the brainstem mimicking a malignant tumor. 　Nambu K, Misaki K, Yoshikawa A, Kamide T, Nambu I, Sasagawa Y, Uchiyama N, Nakada M.　World Neurosurg　140　327　2020
  • 　Motor functional reorganization are triggered by tumor infiltration into the primary motor area and repeated surgery.　Nakajima R, Kinoshita M, Nakada M　Front Human Neurosci 　14　327　2020
  • 　Identification of 2-fluoropalmitic acid as a potential therapeutic agent against glioblastoma.　Jiapaer S, Furuta T, Dong Y, Kitabayashi T, Sabit H, Zhang J, Zhang G, Tanaka S, Kobayashi M, Hirao A, Nakada M.　Curr Pharm Des　111　2413-2422　2020/04/23
  • 　Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.　Zhang J, Furuta T, Sabit H, Tamai S, Jiapaer S, Dong Y, Kinoshita M, Uchida Y, Ohtsuki S, Terasaki T, Zhao S, Nakada M.　Cancer Science　111　2413-2422　2020
  • 　RBPJ contributes to the malignancy of glioblastoma and induction of proneural-mesenchymal transition via IL-6-STAT3 pathway.　Zhang G, Tanaka S, Jiapaer S, Sabit H, Tamai S, Kinoshita M, Nakada M.　Cancer Science　2020/09/03
  • 　TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.　Arita H, Matsushita Y, Machida R, Yamasaki K, Hata N, Ohno M, Yamaguchi S, Sasayama T, Tanaka S, Higuchi F, Iuchi T, Saito K, Kanamori M, Matsuda KI, Miyake Y, Tamura K, Tamai S, Nakamura T, Uda T, Okita Y, Fukai J, Sakamoto D, Hattori Y, Pareira ES, Hatae R, Ishi Y, Miyakita Y, Tanaka K, Takayanagi S, Otani R, Sakaida T, Kobayashi K, Saito R, Kurozumi K, Shofuda T, Nonaka M, Suzuki H, Shibuya M, Komori T, Sasaki H, Mizoguchi M, Kishima H, Nakada M, Sonoda Y, Tominaga T, Nagane M, Nishikawa R, Kanemura Y, Kuchiba A, Narita Y, Ichimura K.　Acta Neuropathol Commun　8　201　2020
  • 　Pyramid-shape crossings and inter-crossing fibers are key elements for construction of the neural network in the superficial white matter of the human cerebrum. 　Shinohara H, Liu X, Nakajima R, Kinoshita M, Ozaki N, Hori O, Nakada M.　Cerebral Cortex　30　5218-5228　2020
  • 　The multipotential of leucine-rich α-2 glycoprotein 1 as a clinicopathological biomarker of glioblastoma.　Furuta T, Sugita Y, Komaki S, Ohshima K, Morioka M, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T, Nakada M.　J Neuropathol Exp Neurol 　79　873-879　2020
  • 　Oculomotor nerve palsy in pituitary apoplexy associated with pituitary adenoma: a radiological analysis with fast imaging employing with steady-state acquisition.　Sasagawa Y, Aburano H, Ooiso K, Oishi M, Hayashi Y, Nakada M.　Acta Neurochir (Wien)　2020/10/31
  • 　Ependymoma with C11orf95-MAML2 fusion: Presenting with granular cell and ganglion cell features.　Tamai S, Nakano Y, Kinoshita M, Sabit H, Nobusawa S, Arai Y, Hama N, Totoki Y, Shibata T, Ichimura K, Nakada M.　Brain Tumor Pathol 　2020/11/22
  • 　So-called “bifocal tumors” with diabetes insipidus and negative tumor markers: Are they all germinoma?　Kanamori M, Takami H, Yamaguchi S, Sasayama T, Yoshimoto K, Tominaga T, Inoue A, Ikeda N, Kambe A, Kumabe T, Matsuda M, Tanaka S, Natsumeda M, Matsuda KI, Nonaka M, Jun K, Yamaoka M, Kagawa N, Shinojima N, Negoto T, Nakahara Y, Arakawa Y, Hatazaki S, Shimizu H, Yoshino A, Abe H, Akimoto J, Kawanishi Y, Suzuki T, Natsume A, Nagane M, Akiyama Y, Keino D, Fukami T, Tomita T, Kanaya K, Tokuyama T, Izumoto S, Nakada M, Kuga D, Yamamoto S, Anei R, Uzuka T, Fukai J, Kijima N, Terashima K, Ichimura K, Nishikawa R.　Neuro-Oncol　2020/08/20
  • 　Inflow hemodynamics of intracranial aneurysms: a comparison of computational fluid dynamics and 4D flow magnetic resonance imaging.　Misaki K, Futami K, Uno T, Nambu I, Yoshikawa A, Kamide T, Nakada M.　J Stroke Cerebrovasc Dis. 　30　105685　2021
  • 　A Case of rapid deterioration in a subacute period after endoscopic third ventriculostomy.　Ichinose T, Hayashia Y, SasagawaY, Oishi M, Higashi R, Nakada M.　2021
  • 　Preserving right pre-motor and posterior prefrontal cortices contribute to maintaining overall basic emotion.　Nakajima R, Kinoshita M, Okita H, Liu Z, Nakada M.　Front Hum Neurosci　15　612890　2021
  • 　Prediction of post-embolization recurrence of anterior communicating aneurysms with A1 segment asymmetry by fluid dynamic analysis.　Misaki K, Uno T, Nambu I, Yoshikawa A, Kamide T, Uchiyama N, Nakada M　J Neuroendovasc Ther　2020
  • 　Asymptomatic carotid intraplaque hemorrhage is associated with a high risk of cerebral infarction and death after cardiovascular surgery　Misaki K, Uno T, Nambu I, Kimura R, Yoshikawa A, Kamide T, Hayashi Y, Uchiyama N, Iino K, Takemura H, Nakada M.　J Neurol Sci 　412　116801　2020
  • 　Usefulness of 2D-perfusion analysis for the assessment of unilateral cervical internal carotid artery stenosis 　Yoshikawa A, Uno T, Nambu I, Kamide T, Misaki K, Nakada M　JNET　2020
  • 　Progressively Enlarged Convexity Arachnoid Cysts in Elderly Patients: A Report of 2 Cases. 　Kimura R, Hayashi Y, Sasagawa Y, Kobayashi M, Oishi M, Kinoshita M, Nakada M.　World Neurosurg　135　253-358　2020
  • 　Cavernous sinus dural arteriovenous fistula with an enhanced lesion in the brainstem mimicking a malignant tumor. 　Nambu K, Misaki K, Yoshikawa A, Kamide T, Nambu I, Sasagawa Y, Uchiyama N, Nakada M.　World Neurosurg　140　327　2020
  • 　Motor functional reorganization are triggered by tumor infiltration into the primary motor area and repeated surgery.　Nakajima R, Kinoshita M, Nakada M　Front Human Neurosci 　14　327　2020
  • 　Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.　Zhang J, Furuta T, Sabit H, Tamai S, Jiapaer S, Dong Y, Kinoshita M, Uchida Y, Ohtsuki S, Terasaki T, Zhao S, Nakada M.　Cancer Science　111　2413-2422　2020
  • 　Pyramid-shape crossings and inter-crossing fibers are key elements for construction of the neural network in the superficial white matter of the human cerebrum. 　Shinohara H, Liu X, Nakajima R, Kinoshita M, Ozaki N, Hori O, Nakada M.　Cerebral Cortex　30　5218-5228　2020
  • 　PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma.　Furuse M, Kuwabara H, Ikeda N, Hattori Y, Ichikawa T, Kagawa N, Kikuta K, Tamai S, Nakada M, Wakabayashi T, Wanibuchi M, Kuroiwa T, Hirose Y, Miyatake SI. 　BMC Cancer　20　277　2020
  • 　Potential therapeutic effect of targeting glycogen synthase kinase 3β in esophageal squamous cell carcinoma.　Bolidong D, Domoto T, Uehara M, Sabit H, Okumura T, Endo Y, Nakada M, Ninomiya I, Miyashita T, Wong RW, Minamoto T.　Sci Rep　10　11807　2020
  • 　The multipotential of leucine-rich α-2 glycoprotein 1 as a clinicopathological biomarker of glioblastoma.　Furuta T, Sugita Y, Komaki S, Ohshima K, Morioka M, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T, Nakada M.　J Neuropathol Exp Neurol 　79　873-879　2020
  • 　Glioma stem-like cells can be targeted in boron neutron capture therapy with boronophenylalanine　Kondo N, Hikida M, Nakada M, Sakurai Y, Hirata E, Takeno S, Suzuki M. 　Cancers (Basel)　12　3040　2020
  • 　Prediction of post-embolization recurrence of anterior communicating aneurysms with A1 segment asymmetry by fluid dynamic analysis.　Misaki K, Uno T, Nambu I, Yoshikawa A, Kamide T, Uchiyama N, Nakada M　J Neuroendovasc Ther　2020
  • 　PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma.　Furuse M, Kuwabara H, Ikeda N, Hattori Y, Ichikawa T, Kagawa N, Kikuta K, Tamai S, Nakada M, Wakabayashi T, Wanibuchi M, Kuroiwa T, Hirose Y, Miyatake SI. 　BMC Cancer　20　277　2020
  • 　Progressively Enlarged Convexity Arachnoid Cysts in Elderly Patients: A Report of 2 Cases. 　Kimura R, Hayashi Y, Sasagawa Y, Kobayashi M, Oishi M, Kinoshita M, Nakada M.　World Neurosurg　135　253-358　2020
  • 　Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.　Zhang J, Furuta T, Sabit H, Tamai S, Jiapaer S, Dong Y, Kinoshita M, Uchida Y, Ohtsuki S, Terasaki T, Zhao S, Nakada M.　Cancer Science　111　2413-2422　2020
  • 　Cavernous sinus dural arteriovenous fistula with an enhanced lesion in the brainstem mimicking a malignant tumor. 　Nambu K, Misaki K, Yoshikawa A, Kamide T, Nambu I, Sasagawa Y, Uchiyama N, Nakada M.　World Neurosurg　140　327　2020
  • 　TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.　Arita H, Matsushita Y, Machida R, Yamasaki K, Hata N, Ohno M, Yamaguchi S, Sasayama T, Tanaka S, Higuchi F, Iuchi T, Saito K, Kanamori M, Matsuda KI, Miyake Y, Tamura K, Tamai S, Nakamura T, Uda T, Okita Y, Fukai J, Sakamoto D, Hattori Y, Pareira ES, Hatae R, Ishi Y, Miyakita Y, Tanaka K, Takayanagi S, Otani R, Sakaida T, Kobayashi K, Saito R, Kurozumi K, Shofuda T, Nonaka M, Suzuki H, Shibuya M, Komori T, Sasaki H, Mizoguchi M, Kishima H, Nakada M, Sonoda Y, Tominaga T, Nagane M, Nishikawa R, Kanemura Y, Kuchiba A, Narita Y, Ichimura K.　Acta Neuropathol Commun　8　201　2020
  • 　Pyramid-shape crossings and inter-crossing fibers are key elements for construction of the neural network in the superficial white matter of the human cerebrum. 　Shinohara H, Liu X, Nakajima R, Kinoshita M, Ozaki N, Hori O, Nakada M.　Cerebral Cortex　30　5218-5228　2020
  • 　Motor functional reorganization are triggered by tumor infiltration into the primary motor area and repeated surgery.　Nakajima R, Kinoshita M, Nakada M　Front Human Neurosci 　14　327　2020
  • 　Usefulness of 2D-perfusion analysis for the assessment of unilateral cervical internal carotid artery stenosis 　Yoshikawa A, Uno T, Nambu I, Kamide T, Misaki K, Nakada M　JNET　2020
  • 　Asymptomatic carotid intraplaque hemorrhage is associated with a high risk of cerebral infarction and death after cardiovascular surgery　Misaki K, Uno T, Nambu I, Kimura R, Yoshikawa A, Kamide T, Hayashi Y, Uchiyama N, Iino K, Takemura H, Nakada M.　J Neurol Sci 　412　116801　2020
  • 　Glioma stem-like cells can be targeted in boron neutron capture therapy with boronophenylalanine　Kondo N, Hikida M, Nakada M, Sakurai Y, Hirata E, Takeno S, Suzuki M. 　Cancers (Basel)　12　3040　2020
  • 　The multipotential of leucine-rich α-2 glycoprotein 1 as a clinicopathological biomarker of glioblastoma.　Furuta T, Sugita Y, Komaki S, Ohshima K, Morioka M, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T, Nakada M.　J Neuropathol Exp Neurol 　79　873-879　2020
  • 　Potential therapeutic effect of targeting glycogen synthase kinase 3β in esophageal squamous cell carcinoma.　Bolidong D, Domoto T, Uehara M, Sabit H, Okumura T, Endo Y, Nakada M, Ninomiya I, Miyashita T, Wong RW, Minamoto T.　Sci Rep　10　11807　2020
  • 　Asymptomatic carotid intraplaque hemorrhage is associated with a high risk of cerebral infarction and death after cardiovascular surgery　Misaki K, Uno T, Nambu I, Kimura R, Yoshikawa A, Kamide T, Hayashi Y, Uchiyama N, Iino K, Takemura H, Nakada M.　J Neurol Sci 　412　116801　2020
  • 　Prediction of post-embolization recurrence of anterior communicating aneurysms with A1 segment asymmetry by fluid dynamic analysis.　Misaki K, Uno T, Nambu I, Yoshikawa A, Kamide T, Uchiyama N, Nakada M　J Neuroendovasc Ther　2020
  • 　TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.　Arita H, Matsushita Y, Machida R, Yamasaki K, Hata N, Ohno M, Yamaguchi S, Sasayama T, Tanaka S, Higuchi F, Iuchi T, Saito K, Kanamori M, Matsuda KI, Miyake Y, Tamura K, Tamai S, Nakamura T, Uda T, Okita Y, Fukai J, Sakamoto D, Hattori Y, Pareira ES, Hatae R, Ishi Y, Miyakita Y, Tanaka K, Takayanagi S, Otani R, Sakaida T, Kobayashi K, Saito R, Kurozumi K, Shofuda T, Nonaka M, Suzuki H, Shibuya M, Komori T, Sasaki H, Mizoguchi M, Kishima H, Nakada M, Sonoda Y, Tominaga T, Nagane M, Nishikawa R, Kanemura Y, Kuchiba A, Narita Y, Ichimura K.　Acta Neuropathol Commun　8　201　2020

Conference Presentations

  • 前方言語野ネットワークにおけるコア領域と機能シフトの解析(2023/01/20)
  • Optic/Hypothalamic Glioma(conference：4th Congress of Asian-Australasian Society for Pediatric Neurosurgery (AASPN) 2023)(2023/12/13)
  • Glioblastomas located in the right inferior parietal lobe causes a poor postoperative performance level.(conference：Society for Neuro-Oncology 28th Annual Meeting 2023)(2023/11/15)
  • Blood biomarkers distinguishing pseudoprogression from recurrence in glioblastoma.(conference：23rd International Conference on Brain Tumor Research and Therapy )(2023/05/26)
  • Deep white matter portion of dorsal superior longitudinal fascicle is a critical region for preservation of visuospatial cognition during glioma surgery(conference：The 6th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies (WFNOS)/The 17th Meeting of the Asian Society for Neuro-Oncology (ASNO))(2022/03/24)

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  • 視空間認知と作業記憶の温存を意図した右前頭葉グリオーマ摘出時の不可侵領域の策定(2021/09/09)
  • 高次脳機能温存のための白質解剖(2021/05/13)
  • Factors influencing poor independence level following resection of the right temporo-parietal glioblastomas(conference：Society for Neuro-Oncology 26th Annual Meeting 2021)(2021/11/18)
  • Awake surgery for right frontal lobe glioma can preserve visuospatial cognition and spatial working memory(conference：2021 CNS Annual Meeting)(2021/10/16)
  • Preservation of deep posterior part of the middle frontal gyrus and cingulate gyrus zone II prevents visuospatial cognition and working memory impairment during right frontal glioma surgery(conference：2021 CNS Annual Meeting)(2021/10/16)
  • 脳腫瘍治療における脳機能を守り抜く戦い(2021/07/21)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

○The molecular analysis of malignant glioma
○The molecular mechanism of glioma invasion
○localization of brain function
○Neural network
○Molecular targeted therapy for malignant glioma
○The developement of apparatus for neurosurgery

Grant-in-Aid for Scientific Research

○2024「人種間の他者理解脳内ネットワーク解析と覚醒下手術への応用」(2020-2024)　
○2021「脳腫瘍進展に伴う脳機能シフトの法則と限界の解明」(2020-2021)　
○「悪性神経膠腫由来のエクソソームを介したミクログリアによる微小環境整備の解明」(2018-2020)　
○「高次脳機能局在に基づく右前頭葉腫瘍に対する摘出限界策定の試み」(2018-2019)　
○「次世代プロテオミクスによる悪性グリオーマのバイオマーカー探索」(2016-2017)　
○「標的タンパク発現プロファイルに基づく新規膠芽腫分類の試み」(2014-2015)
○「ドラッグリポジショニングによる悪性グリオーマに対する新規化学療法の基盤構築」(2014-2016)
○「グリオーマ幹細胞の浸潤関連分子の同定と機能解析」(2009-2010)　
○「Eph/ephrinバイオロジーと神経膠腫浸潤」(2007-2008)　
○「新規細胞外マトリックス分解酵素阻害分子による神経膠芽腫」(2002-)　
○「右前頭葉機能の賦活・抑制に関わる新規神経機能ネットワークの解明」(2019-2020)　
○「感情識別機能の術後回復に伴う神経ネットワーク再編成メカニズムの解明」(2018-2020)　
○「膜型マトリックスメタロプロテアーゼ－１のがん悪性化形質に果たす役割の解析」(2009-)　
○「神経膠芽腫の浸潤に関与する転写因子と細胞外マトリックス」(2002-)　
○「膠芽腫医療に抜本的変革をもたらす血液バイオマーカーの分子基盤の構築」(2022-2025)　
○「言語機能回復に伴う脳内ネットワーク再組織化の構造的メカニズムの解明」(2021-2023)　
○「回復期待度による新規リハビリテーション指針確立に向けた白質神経線維の可塑性の解明」(2021-2022)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

○Neurosurgery(2021)
○Neurosurgery(2021)

International Project

International Students

Lecture themes

Others (Social Activities)

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