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Researcher Information

last modified:2017/08/09

Associate Professor TAOKA Azuma

Mail Laboratory Website

Faculty, Affiliation

Faculty of Natural System, Institute of Science and Engineering

College and School Educational Field

Division of Natural Sciences, Graduate School of Natural Science and Technology

Laboratory

 TEL:076-264-6234 FAX:076-264-6230

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Department of Life Science 200403 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University Department of Biology 199903
【Degree】
Ph. D.
Master of Science

Career

Postdoctoral researcher Faculty of Science(2004/09/13-2007/08/31)
VBL Postdoctoral researcher Venture Business Laboratory(2007/09/01-2008/03/31)

Year & Month of Birth

1976/02

Academic Society

The Japanese Biochemical Society
The Japanese Society of Microbial Ecology
American Society for Microbiology
Japanese Society for Bacteriology

Society of Genome Microbiology, Japan

Award

Society of Genome Microbiology, Japan

Specialities

Functional biochemistry、Applied microbiology

Speciality Keywords

Prokaryotic organelle, Bacterial cytoskeleton, Magnetotactic Bacteria, Magnetosome

Research Themes

Molecular mechanisms for magnetic organelle 'magnetosome' of magnetotactic bacnteria

Molecular mechanisms for magnetic organelle 'magnetosome' of magnetotactic bacnteria Magnetic bacteria are unique bacteria that are able to sense magnetism with a prokaryotic cell organelle called magnetosome which functions as a magnetic compass. Magnetic bacteria take in iron from the environment and synthesize magnetite crystals in their cellular membrane vesicles. Magnetosome is a complex intracellular structure with these membrane vesicles arranged in a string-like pattern along the cellular skeleton. We conduct research using biochemical and molecular biological techniques and various microscopic techniques in order to explain how magnetosomes develop and function at the molecular level. We aim to explain organelle development in prokaryotic organisms and the mechanism of biomineralization with this research.

Books

Papers

  •  Tethered magnets are the key to magnetotaxis: direct observations of Magnetospirillum magneticum AMB-1 show that MamK distributes magnetosome organelles equally to daughter cells. Taoka, A., Kiyokawa, A., Uesugi, C., Kikuchi, Y., Oestreicher, A., Morii, K., Eguchi, Y., Fukumori, Y. mBio 8 4 e00679-17 2017/08
  •  High-Speed Atomic Force Microscopy Reveals Loss of Nuclear Pore Resilience as a Dying Code in Colorectal Cancer Cells Mohamed MS, Kobayashi A, Taoka A, Watanabe-Nakayama T, Kikuchi Y, Hazawa M, Minamoto T, Fukumori Y, Kodera N, Uchihashi T, Ando T, Wong RW. ACS Nano 11 6 5567-5578 2017/05
  •  A protein-protein interaction in magnetosomes: TPR 1 protein MamA interacts with an Mms6 protein Hoang Viet Nguyen, Emi Suzuki, Zachery Oestreicher, Hiroshi Minamide, Hiroshi Endoh, Yoshihiro Fukumori, Azuma Taoka Biochemistry and Biophysics Reports  7 39–44 2016/09
  •  Live-Cell Imaging of Bacterial Cells Using High-Speed Atomic Force Microscopy Azuma TAOKA, Yoshihiro FUKUMORI in press 2015/05
  •  A comparison of the surface nanostructure from two different types of gram-negative cells: Escherichia coli and Rhodobacter sphaeroides Z.W. Oestreicher, A. Taoka, Y. Fukumori Micron 8-14 72 2015/02

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  •  Characterization of uncultured giant rod-shaped magnetotactic Gammaproteobacteria from a fresh water pond in Kanazawa, Japan Azuma Taoka, Junya Kondo, Zachery Oestreicher, and Yoshihiro Fukumori MICROBIOLOGY-SGM 160 10 2226-2234 2014/07
  •  A magnetosome-associated cytochrome MamP is critical for magnetite crystal growth during the exponential growth phase Azuma Taoka, Yukako Eguchi, Shingo Mise, Zachery Oestreicher, Fumio Uno and Yoshihiro Fukumori FEMS MICROBIOLOGY LETTERS 358 1 21-29 2014/07
  •  Extranuclear dynamics of 111Ag(→111Cd) doped in AgI nanoparticles W. Sato, R. Mizuuchi, N. Irioka, S. Komatsuda, S. Kawata, A. Taoka, Y. Ohkubo CHEMICAL PHYSICS LETTERS 609 104-107 2014/06
  •  Purification, Characterization, and Crystallization of Crocodylus siamensis Hemoglobin  Jandaruang J., Siritapetawee J., Songsiriritthigul C., Preecharram S., Taoka A., Dhiravisit A., Fukumori Y., Thammasirirak S. The Protein Journal 33 4 377-385 2014/08
  •  Structure and Function of Magnetotactic Bacterial Organelle “Magnetosome" Fukumori, Y., Taoka, A 54 1 11-14 2014/01
  •  Purification and Characterization of Coacervate-Forming Cuticular Proteins from Papilio xuthus Pupae Masahiro Yamanaka, Yumi Ishizaki, Taro Nakagawa, Azuma Taoka and Yoshihiro Fukumori ZOOLOGICAL SCIENCE 30 7 534-542 2013/07
  •  Analysis of magnetotactic behavior by swimming assay. Sakaguchi Sakaguchi, Taoka Azuma, Fukumori Yoshihiro. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77 5 940-947 2013/05
  •  Single-Molecule Imaging on Living Bacterial Cell Surface by High-Speed AFM Hayato Yamashita†, Azuma Taoka†(共同筆頭著者), Takayuki Uchihashi, Tomoya Asano, Toshio Ando, Yoshihiro Fukumori (†: H.Y. and A.T. contributed equally to this work.) JOURNAL OF MOLECULAR BIOLOGY 422 2 300-309 2012/05
  •  Visualization and structural analysis of the bacterial magnetic organelle magnetosome using atomic force microscopy Yamamoto, D.*, Taoka, A.*(共同筆頭著者), Uchihashi, T., Sasaki, H., Watanabe, H., Ando, T., and Fukumori, Y. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME 107 21  9382-9387 2010/05
  •  Spatial localizations of Mam22 and Mam12 in the magnetosomes of Magnetospirillum magnetotacticum Taoka, A., Asada, R., Sasaki, H., Anzawa, K., Wu, L-F., and Fukumori, Y. JOURNAL OF BACTERIOLOGY 188 11  3805-3512 2006/06
  •  Identification of iron transporters expressed in the magnetotactic bacterium Magnetospirillum magnetotacticum. Taoka A, Umeyama C, Fukumori Y. CURRENT MICROBIOLOGY 58 2 177-181 2009/01
  •  Polymerization of the actin-like protein MamK, which is associated with magnetosomes. Taoka, A., Asada, R., Wu, L-F., and Fukumori, Y. JOURNAL OF BACTERIOLOGY 189 23  8737-8740 2007/12
  •  Strucuture and cellular localization of bacterial magnetic organelle Y. Fukumori, A. Taoka 45 3 154-156 2007/03
  •  Participation of nitric oxide reductase in survival of Pseudomonas aeruginosa in LPS-activated macrophages Kakishima, K., Shiratsuchi, A., Taoka, A., Nakanishi, Y., and Fukumori, Y. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2007/04
  •  Biosynthesis of magnetite particles in magnetic bacteria Y. Fukumori, A. Taoka 24 12 5-13 2007/12
  •  Nitrate reductase from the magnetotactic bacterium Magnetospirillum magnetotacticum MS-1: purification and sequence analyses Taoka, A., Yoshimatsu, K., Kanemori, M., and Fukumori, Y. CANADIAN JOURNAL OF MICROBIOLOGY 49  197-206 2003/05

Conference Presentations

  • Electron transfer pathway mediated by MamP for magnetite biomineralization(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • Bacterial magnetotactic motility and magnetosome organelle (2017/03/21)
  • The actin-like cytoskeletal protein MamK plays a role in positioning of magnetic organelles for bacterial magnetotactic motility(2016/11/27)
  • Motility of magnetotactic bacteria and cytoskeletal element for magnetosomes positioning(2016/07/24)
  • 高速原子間力顕微鏡を用いた癌細胞の核膜孔動態の可視化(2016/11/25)

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  • High-speed atomic force microscopy visualization of the nuclear pores dynamics in colon cancer cells(conference:4th Kanazawa Bio-AFM Workshop 2016)(2016/10/06)
  • A new look at the nanostructure of the outer surface of living Proteobacteria using the high-speed atomic force microscope(conference:4th Kanazawa Bio-AFM Workshop 2016)(2016/10/06)
  • The actin-like cytoskeletal protein MamK and its ATPase activity play a role in the positioning of magnetosomes(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • DIRECT OBSERVATION OF ACTIN-LIKE MAMK CYTOSKELETAL FILAMENTS BY HS-AFM(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • Polarity of a bacterial nano-compass reversed by magnetic tweezers(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • Functional analysis of a magnetotactic bacterial actin-like cytoskeleton MamK using fluorescence live-cell imaging(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • Visualization of flagellar rotation during magnetotactic motility using Magnetospirillum magneticum AMB-1(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • A protein-protein interaction in magnetosome: MamA oligomer interacts with Mms6 oligomer(conference:Magnetotactic Bacteria 5th International Meeting)(2016/09/11)
  • “A protein-protein interaction in bacterial magnetic organelle: TPR protein MamA interacts with magnetite biomineralizing protein Mms6”(2016/05/28)

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「原核細胞の細胞骨格による磁気感知オルガネラ配置の分子機構」(2016-) 
○「磁性細菌の磁気微粒子合成に関わる新奇ヘム蛋白質の機能解明」(2013-2015) 
○「「磁場」を感知するバクテリアの磁気オルガネラを支える細胞骨格」(2011-2012) 
○「原核細胞の磁気オルガネラの生細胞イメージングー形成・機能メカニズムの解明ー」(2010-2012) 

Classes (Bachelors)

○Research Work in Biology(1)(2017)
○Research Seminar in Biology (2)(2017)
○Basic Biology Lab(2017)
○Guide to Biology and Earth Sciences(2017)
○GS English Language for Undergraduates I (English for Science and Engineering)(2017)
○Research Seminar in Biology (1)(2017)
○Biochemistry Lab(2017)
○Biochemistry Seminar(2017)
○Advanced Biology Lab(2017)
○Group Seminar of Biology(2017)
○Research Work in Biology(2)(2017)
○GS English Language for Undergraduates II (English for Science and Engineering)(2017)
○Experiments in Biology(2017)
○Molecular and Cellular Biology(2017)
○Experiments in Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2016)
○Molecular and Cellular Biology(2016)
○Molecular and Cellular Biology(2016)
○Experiments in Biology(2016)
○Biochemistry Seminar(2016)
○Biochemistry Lab(2016)
○Research Work in Biology(2)(2016)
○Research Work in Biology(1)(2016)
○Research Seminar in Biology (2)(2016)
○Research Seminar in Biology (1)(2016)
○Experiments in Biology(2016)

Classes (Graduate Schools)

○Molecular Microbiology(2017)
○Molecular Microbiology(2017)
○Research work in Systems Biology(2017)
○Exercise in Systems Biology 2B(2017)
○Exercise in Systems Biology 2A(2017)
○Exercise in Systems Biology 1B(2017)
○Exercise in Systems Biology 1A(2017)
○Research work in Systems Biology(2017)
○Research Skills B(2017)
○Molecular Microbiology(2017)
○Research Skills A(2017)
○Genomic Systems Biology B(2017)
○Basic Systems Biology B(2017)
○Basic Exercise in Systems Biology(2017)
○Special Lecture on Systems Biology(2017)
○Basic Systems Biology A(2017)
○Systems structure and function in biomolecules B(2017)
○Basic Systems Biology A(2017)
○Basic Systems Biology B(2017)
○Molecular Microbiology(2017)
○Systems structure and function in biomolecules(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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