北尾 梓 (きたお あずさ) 教授 Azusa Kitao

所属組織・役職等
医薬保健研究域 保健学系 医療科学領域 量子医療技術学講座
教育分野
所属研究室等
金沢大学医薬保健研究域 保健学系 医療科学領域 量子医療技術学講座
学歴
【出身大学院】
金沢大学大学院 博士課程 医学系研究科 2010 修了
【出身大学】
金沢大学 医学部医学科 2002 卒業
【取得学位】
博士(医学)
職歴
金沢大学附属病院 放射線科 講師(2019/04/01-2024/02/29)
金沢大学医薬保健研究域 保健学系 医療科学領域 量子医療技術学講座 教授(2024/03/01-)
生年月
所属学会
日本医学放射線学会 代議員(2022-2023)
北米放射線学会
日本腹部放射線学会
日本肝癌研究会
日本磁気共鳴医学会
学内委員会委員等
受賞学術賞
○第108回北米放射線学会 Certificate of Merit(2022)
○金沢大学はあざみ女性研究者賞(2020)
○第12回金沢市医師会記念館医学賞(2018)
○第77回日本医学放射線学会総会 CyPOS 優秀教育展示賞(2018)
○第23回肝血流動態イメージング研究会 板井悠二賞(2017)
○第22回肝血流動態イメージング研究会 板井悠二賞(2016)
○第71回日本医学放射線学会総会 CyPOS Platinum Medal(2012)
○第2回アジア太平洋肝癌専門家会議 Bronze Medal(2011)
○第70回日本医学放射線学会総会 CyPOS Gold Medal(2011)
○第17回肝血流動態イメージング研究会 板井悠二賞(2011)
○日独医報 最優秀論文賞(2010)
○第69回日本医学放射線学会総会 CyPOS Silver Medal(2010)
○第16回肝血流動態イメージング研究会 板井悠二賞(2010)
○第45回日本肝臓学会総会 優秀演題賞(2009)
○第68回日本医学放射線学会 優秀論文賞(2009)
○欧州放射線学会 Magna Cum Laude Award(2009)
○第12回アジアオセアニア放射線学会 Scientific Exhibition Silver Award(2008)
○第37回IVR学会総会 Cum Laude Award(2008)
○第14回肝血流動態イメージング研究会 板井悠二賞(2008)
専門分野
放射線科学
専門分野キーワード
肝,Imaging diagnosis,画像診断
研究課題
著書
論文
- Dynamic CT and Gadoxetic Acid-enhanced MRI Characteristics of P53-mutated Hepatocellular Carcinoma. Kitao A, Matsui O, Zhang Y, Ogi T, Nakada S, Sato Y, Harada K, Yoneda N, Kozaka K, Inoue D, Yoshida K, Koda W, Yamashita T, Yamashita T, Kaneko S, Kobayashi S, Gabata T. Radiology 306巻 e220531頁 2023
- Gadoxetic acid enhanced MR imaging for hepatocellular carcinoma: molecular and genetic background. Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Koda W, Inoue D, Ogi T, Yoshida K, Gabata T. European Radiology 30巻 6号 3438-3447頁 2020
- Gadoxetic acid-enhanced magnetic resonance imaging reflects co-activation of β-catenin and hepatocyte nuclear factor 4α in hepatocellular carcinoma. Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Koda W, Minami T, Inoue D, Yoshida K, Yamashita T, Yamashita T, Kaneko S, Takamura H, Ohta T, Ikeda H, Sato Y, Nakanuma Y, Harada K, Kita R, Gabata T. Hepatology Research 48巻 2号 205-216頁 2017
- Differentiation between hepatocellular carcinoma showing hyperintensity on the hepatobiliary phase of gadoxetic acid enhanced MRI and focal nodular hyperplasia by CT and MRI Kitao A, Matsui O, Yoneda N, Kita R, Kozaka K, Kobayashi S, Gabata T. American Journal of Roentgenology 211巻 2号 347-357頁 2018
- Hepatocellular Carcinoma with β-Catenin Mutation: Imaging and Pathologic Characteristics. Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Sanada J, Koda W, Minami T, Inoue D, Yoshida K, Yamashita T, Yamashita T, Kaneko S, Takamura H, Ohta T, Ikeda H, Nakanuma Y, Kita R, Gabata T. Radiology 275巻 3号 708-17頁 2015
- Hypervascular hepatocellular carcinoma: correlation between biologic features and signal intensity on gadoxetic acid-enhanced MR images. Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Koda W, Gabata T, Yamashita T, Kaneko S, Nakanuma Y, Kita R, Arii S Radiology 265巻 780-9頁 2012
- The uptake transporter OATP8 expression decreases during multistep hepatocarcinogenesis: correlation with gadoxetic acid enhanced MR imaging. Kitao A, Matsui O, Yoneda N, Kozaka K, Shinmura R, Koda W, Kobayashi S, Gabata T, Zen Y, Yamashita T, Kaneko S, Nakanuma Y. Eur Radiol 21巻 2056-66頁 2011
- Hepatocellular carcinoma: signal intensity at gadoxetic acid-enhanced MR Imaging-correlation with molecular transporters and histopathologic features. Kitao A, Zen Y, Matsui O, Gabata T, Kobayashi S, Koda W, Kozaka K, Yoneda N, Yamashita T, Kaneko S, Nakanuma Y. Radiology 256巻 817-26頁 2010
- Hepatocarcinogenesis: multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography radiologic-pathologic correlation. Kitao A, Zen Y, Matsui O, Gabata T, Nakanuma Y. Radiology 252巻 605-14頁 2009 査読有
- Endothelial to mesenchymal transition via transforming growth factor-beta1/Smad activation is associated with portal venous stenosis in idiopathic portal hypertension. Kitao A, Sato Y, Sawada-Kitamura S, Harada K, Sasaki M, Morikawa H, Shiomi S, Honda M, Matsui O, Nakanuma Y. Am J Pathol 175巻 616-26頁 2009 原著論文
- Super delayed phase imaging in gadoxetic acid-enhanced MRI: investigating factors contributing to improved liver contrast. European radiology 35巻 6号 3195頁 2025/06 研究論文(学術雑誌)
- Hepatobiliary and Pancreatic Neoplasms: Essential Predictive Imaging Features for Personalized Therapy RadioGraphics 45巻 3号 2025/03/01 研究論文(学術雑誌)

- Fat fraction and R2 * values of various liver masses: Initial experience with 6-point Dixon method on a 3T MRI system. European journal of radiology open 11巻 100519頁 2023/12 研究論文(学術雑誌)
- Radiation dose considerations in digital radiography with an anti‐scatter grid: A study using adult and pediatric phantoms Journal of Applied Clinical Medical Physics 24巻 9号 2023/07/25 研究論文(学術雑誌)

- Imaged periductal infiltration: Diagnostic and prognostic role in intrahepatic mass-forming cholangiocarcinoma. European journal of radiology open 12巻 100554頁 2024/06 研究論文(学術雑誌)
- Reactive lymphoid hyperplasia of the liver: A case report featuring characteristic nodular and perinodular enhancement. Radiology case reports 19巻 5号 1998頁 2024/05
- Hepatocellular Carcinoma: It Is Time to Focus on Prognosis Radiology 307巻 3号 2023/05/01 研究論文(学術雑誌)

- Universal Liver Imaging Lexicon: Imaging Atlas for Research and Clinical Practice RadioGraphics 43巻 2号 2023/02/01 研究論文(学術雑誌)

- A case of intrahepatic cholangiocarcinoma arising from a simple hepatic cyst via dysplasia and carcinomatous transformation. Abdominal radiology (New York) 47巻 6号 1954頁 2022/06 研究論文(学術雑誌)
- A low albumin level as a risk factor for transient severe motion artifact induced by gadoxetate disodium administration: A retrospective observational study with free-breathing dynamic MRI and an experimental study in rats. PloS one 17巻 3号 e0265588頁 2022 研究論文(学術雑誌)
- Ultrasonography of IgG4-related dacryoadenitis and sialadenitis: Imaging features and clinical usefulness. Modern rheumatology 32巻 5号 986頁 2021/10/16 研究論文(学術雑誌)
- A case report: mucinous carcinoma of extrahepatic bile ducts with periportal calcification suggestive of lymphatic calcification. Abdominal radiology (New York) 50巻 4号 1595頁 2025/04 研究論文(学術雑誌)
- Central bisectionectomy for hepatocellular carcinoma in a patient with indocyanine green excretory defect associated with reduced expression of the liver transporter. Imada S,Kobayashi T,Kitao A,Matsui O,Hashimoto M,Ide K,Ishiyama K,Arihiro K,Tashiro H,Ohdan H Surgical case reports 2巻 1号 89頁 2016/12 査読有 研究論文(学術雑誌)
- Dynamic CT findings of cholangiolocellular carcinoma: correlation with angiography-assisted CT and histopathology ABDOMINAL RADIOLOGY 42巻 3号 861頁 2017/03 査読有 研究論文(学術雑誌)
- Peri-tumoral hyperintensity on hepatobiliary phase of gadoxetic acid-enhanced MRI in hepatocellular carcinomas: correlation with peri-tumoral hyperplasia and its pathological features Abdominal Radiology 43巻 8号 1頁 2017/12/19 査読有 研究論文(学術雑誌)
- Pathology and images of radiation-induced hepatitis: a review article Japanese Journal of Radiology 36巻 4号 241頁 2018/04/01 査読有
- CT imaging comparison between intraductal papillary neoplasms of the bile duct and papillary cholangiocarcinomas. Komori T,Inoue D,Zen Y,Yoneda N,Kitao A,Kozaka K,Yokka A,Toshima F,Matsubara T,Kobayashi S,Gabata T European radiology 29巻 6号 3132頁 2019/06 査読有 研究論文(学術雑誌)
- Photoacoustic imaging of tumour vascular permeability with indocyanine green in a mouse model. European radiology experimental 2巻 1号 5頁 2018 査読有 研究論文(学術雑誌)
- Evaluation of renal oxygen saturation using photoacoustic imaging for the early prediction of chronic renal function in a model of ischemia-induced acute kidney injury. PloS one 13巻 12号 e0206461頁 2018 査読有 研究論文(学術雑誌)
- Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma. Anticancer research 40巻 9号 5211頁 2020/09 査読有 研究論文(学術雑誌)
- Direct-Acting Antiviral Agents Reduce the Risk of Malignant Transformation of Hepatobiliary Phase-Hypointense Nodule without Arterial Phase Hyperenhancement to Hepatocellular Carcinoma on Gd-EOB-DPTA-Enhanced Imaging in the Hepatitis C Virus-Infected Liver. Liver cancer 9巻 3号 261頁 2020/06 査読有 研究論文(学術雑誌)
- Clinical features and diagnostic imaging of cholangiolocellular carcinoma compared with other primary liver cancers: a surgical perspective Technology in Cancer Research & Treatment 19巻 153303382094814頁 2020/01/01 研究論文(学術雑誌)

- Doughnut-like hyperintense nodules on hepatobiliary phase without arterial-phase hyperenhancement in cirrhotic liver: imaging and clinicopathological features. European radiology 29巻 12号 6489頁 2019/12 査読有 研究論文(学術雑誌)
- Pathologic, Molecular, and Prognostic Radiologic Features of Hepatocellular Carcinoma. Radiographics : a review publication of the Radiological Society of North America, Inc 41巻 6号 1611頁 2021/10 研究論文(学術雑誌)
- Transcatheter arterial embolization of iatrogenic massive arterioportal fistula in the liver. Acta radiologica (Stockholm, Sweden : 1987) 63巻 7号 2841851211023995頁 2021/06/14 研究論文(学術雑誌)
- Impaired lesion detectability on gadoxetic acid-enhanced MR imaging in indocyanine green excretory defect: case series of three patients. Japanese journal of radiology 2020/05/27 査読有 研究論文(学術雑誌)
- Current status of imaging biomarkers predicting the biological nature of hepatocellular carcinoma. Yoneda N,Matsui O,Kobayashi S,Kitao A,Kozaka K,Inoue D,Yoshida K,Minami T,Koda W,Gabata T Japanese journal of radiology 37巻 3号 191頁 2019/03 査読有 研究論文(学術雑誌)
- CT Findings of Thoracic Paravertebral Lesions in IgG4-Related Disease. Inoue D,Zen Y,Komori T,Yoshida K,Yoneda N,Kitao A,Kozaka K,Izumozaki A,Matsumoto J,Toshima F,Kobayashi S,Gabata T AJR. American journal of roentgenology 213巻 3号 1頁 2019/05 査読有 研究論文(学術雑誌)
- Early detection of intrahepatic cholangiocarcinoma. Japanese journal of radiology 37巻 10号 669頁 2019/10 査読有 研究論文(学術雑誌)
- Peribiliary glands: development, dysfunction, related conditions and imaging findings. Matsubara T,Kozaka K,Matsui O,Nakanuma Y,Uesaka K,Inoue D,Yoneda N,Yoshida K,Kitao A,Yokka A,Koda W,Gabata T,Kobayashi S Abdominal radiology (New York) 45巻 2号 416頁 2019/11 査読有 研究論文(学術雑誌)
- Relationship between the degree of abdominal wall movement and the image quality of contrast-enhanced MRI: semi-quantitative study especially focused on the occurrence of transient severe motion artifact. Ikeno H,Kobayashi S,Kozaka K,Ogi T,Inoue D,Yoneda N,Yoshida K,Ohno N,Gabata T,Kitao A Japanese journal of radiology 38巻 2号 165頁 2019/11 査読有 研究論文(学術雑誌)
- Differences in 18F-FDG Uptake and Expression of Glucose Transporter Between 2 Distinct Subtypes of Mass-Forming Intrahepatic Cholangiocarcinomas. Clinical nuclear medicine 45巻 6号 e267-e273頁 2020/06 査読有 研究論文(学術雑誌)
- Morphometric changes in liver cirrhosis: aetiological differences correlated with progression BRITISH JOURNAL OF RADIOLOGY 89巻 1059号 20150896頁 2016 査読有 研究論文(学術雑誌)
- Benign Hepatocellular Nodules: Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging Based on Molecular Background RADIOGRAPHICS 36巻 7号 2010頁 2016/11 査読有 研究論文(学術雑誌)
- Biochemical and Clinical Predictive Approach and Time Point Analysis of Hepatobiliary Phase Liver Enhancement on Gd-EOB-DTPA-enhanced MR Images: A Multicenter Study RADIOLOGY 281巻 2号 474頁 2016/11 査読有 研究論文(学術雑誌)
- Serum Laminin γ2 Monomer as a Diagnostic and Predictive Biomarker for Hepatocellular Carcinoma. Hepatology (Baltimore, Md.) 74巻 2号 760頁 2021/08 研究論文(学術雑誌)
- Tumor Hemodynamics and Hepatocarcinogenesis: Radio-Pathological Correlations and Outcomes of Carcinogenic Hepatocyte Nodules. Ueda K,Matsui O,Kitao A,Kobayashi S,Nakayama J,Miyagawa S,Kadoya M ISRN hepatology 2014巻 607628頁 2014 査読有 研究論文(学術雑誌)
- Retroperitoneal Fibrosis: A Clinicopathologic Study With Respect to Immunoglobulin G4 AMERICAN JOURNAL OF SURGICAL PATHOLOGY 33巻 12号 1833頁 2009/12 査読有 研究論文(学術雑誌)
- IgG4-related Lung and Pleural Disease: A Clinicopathologic Study of 21 Cases AMERICAN JOURNAL OF SURGICAL PATHOLOGY 33巻 12号 1886頁 2009/12 査読有 研究論文(学術雑誌)
- Epidermal growth factor induces cytokeratin 19 expression accompanied by increased growth abilities in human hepatocellular carcinoma LABORATORY INVESTIGATION 91巻 2号 262頁 2011/02 査読有 研究論文(学術雑誌)
- Hepatocelluar nodules in liver cirrhosis: hemodynamic evaluation (angiography-assisted CT) with special reference to multi-step hepatocarcinogenesis ABDOMINAL IMAGING 36巻 3号 264頁 2011/06 査読有 研究論文(学術雑誌)
- Hepatocyte transporter expression in FNH and FNH-like nodule: correlation with signal intensity on gadoxetic acid enhanced magnetic resonance images JAPANESE JOURNAL OF RADIOLOGY 30巻 6号 499頁 2012/07 査読有 研究論文(学術雑誌)
- Beta-catenin-activated hepatocellular adenoma showing hyperintensity on hepatobiliary-phase gadoxetic-enhanced magnetic resonance imaging and overexpression of OATP8 JAPANESE JOURNAL OF RADIOLOGY 30巻 9号 777頁 2012/11 査読有 研究論文(学術雑誌)
- Intranodular signal intensity analysis of hypovascular high-risk borderline lesions of HCC that illustrate multi-step hepatocarcinogenesis within the nodule on Gd-EOB-DTPA-enhanced MRI EUROPEAN JOURNAL OF RADIOLOGY 81巻 12号 3839頁 2012/12 査読有 研究論文(学術雑誌)
- Role of Gadolinium-Ethoxybenzyl-Diethylenetriamine Pentaacetic Acid-Enhanced Magnetic Resonance Imaging in the Management of Hepatocellular Carcinoma: Consensus at the Symposium of the 48th Annual Meeting of the Liver Cancer Study Group of Japan ONCOLOGY 84巻 21頁 2013 査読有 研究論文(学術雑誌)
- Intrahepatic periportal high intensity on hepatobiliary phase images of Gd-EOB-DTPA-enhanced MRI: imaging findings and prevalence in various hepatobiliary diseases JAPANESE JOURNAL OF RADIOLOGY 31巻 1号 9頁 2013/01 査読有 研究論文(学術雑誌)
- Usefulness of Gd-EOB-DTPA-enhanced MR imaging in the evaluation of simple steatosis and nonalcoholic steatohepatitis Journal of Magnetic Resonance Imaging 37巻 5号 1137頁 2013/05 査読有 研究論文(学術雑誌)
- Hypervascular hepatocellular carcinomas showing hyperintensity on hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance imaging: a possible subtype with mature hepatocyte nature JAPANESE JOURNAL OF RADIOLOGY 31巻 7号 480頁 2013/07 査読有 研究論文(学術雑誌)
- Hepatic pseudolymphoma: Imaging-pathologic correlation with special reference to hemodynamic analysis Abdominal Imaging 38巻 6号 1277頁 2013/12 査読有 研究論文(学術雑誌)
- Erratum to "Tumor Hemodynamics and Hepatocarcinogenesis: Radio-Pathological Correlations and Outcomes of Carcinogenic Hepatocyte Nodules". Ueda K,Matsui O,Kitao A,Kobayashi S,Nakayama J,Miyagawa S,Kadoya M International scholarly research notices 2014巻 649262頁 2014 査読有
- Hemodynamics and progression of a hypervascular focus in a borderline lesion of hepatocellular carcinoma: analysis by angiography-assisted CT and histopathology JAPANESE JOURNAL OF RADIOLOGY 32巻 2号 69頁 2014/02 査読有 研究論文(学術雑誌)
- Gd-EOB-DTPA-Enhanced Magnetic Resonance Imaging and Alpha-Fetoprotein Predict Prognosis of Early-Stage Hepatocellular Carcinoma HEPATOLOGY 60巻 5号 1674頁 2014/11 査読有 研究論文(学術雑誌)
- Hepatitis C Related Chronic Liver Cirrhosis: Feasibility of Texture Analysis of MR Images for Classification of Fibrosis Stage and Necroinflammatory Activity Grade PLOS ONE 10巻 3号 e0118297頁 2015/03 査読有 研究論文(学術雑誌)
- Correlation between Gd-EOB-DTPA-enhanced MR imaging findings and OATP1B3 expression in chemotherapy-associated sinusoidal obstruction syndrome ABDOMINAL IMAGING 40巻 8号 3099頁 2015/10 査読有 研究論文(学術雑誌)
- Relationship between signal intensity on hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MR imaging and prognosis of borderline lesions of hepatocellular carcinoma EUROPEAN JOURNAL OF RADIOLOGY 81巻 11号 3002頁 2012/11 査読有 研究論文(学術雑誌)
- Intraductal papillary-mucinous neoplasm of the pancreas associated with polycystic liver and kidney disease PATHOLOGY INTERNATIONAL 59巻 3号 201頁 2009/03 査読有 研究論文(学術雑誌)
- A case of hamartomatous proliferation of bile ducts protruding from the liver Japanese Journal of Clinical Radiology 51巻 7号 883頁 2006 研究論文(学術雑誌)
- A case of dedifferentiated liposarcoma Japanese Journal of Clinical Radiology 49巻 6号 807頁 2004 研究論文(学術雑誌)
- Multicystic biliary hamartoma: a hitherto undescribed lesion HUMAN PATHOLOGY 37巻 3号 339頁 2006/03 査読有 研究論文(学術雑誌)
講演・口頭発表等
その他(報告書など)
芸術・フィールドワーク
特許
共同研究希望テーマ
科研費
○基盤研究(C)(一般)「肝細胞癌のradiomicsに基づく薬物治療効果予測」(2021-2024) 代表者
○基盤研究(C)(一般)「肝細胞癌の分子・遺伝子的亜分類に基づいたradiogenomics」(2017-2019) 代表者
○若手研究(B)「β-catenin変異型肝細胞癌のGd-EOB-DTPA造影MRI所見」(2014-2015) 代表者
○若手研究(B)「肝細胞癌のGd-EOB-DTPA造影MRIによるsubtype分類」(2012-2013) 代表者
競争的資金・寄付金等
○助成金 (2018-2018) 研究 肝細胞癌における肝特異性造影MRI所見の分子遺伝子的背景の解明 第12回金沢市医師会記念館医学賞
○助成金 (2016-2016) 研究 肝細胞癌の画像バイオマーカーの確立 北國がん基金
○助成金 (2009-2009) 研究 肝細胞癌およびdysplastic noduleのGd-EOB-DTPA造影MRI像-肝細胞膜トランスポーターOATP1, MRP2の発現に関する基礎的検討- 日本医学放射線学会研究助成
共同研究・受託研究実績
A-STEP採択課題
学域・学類担当授業科目
○実践臨床技術学(2024)
○放射線機器学実験Ⅱ(2024)
○生理検査学Ⅱ(2024)
○病理学B(2024)
○病理学A(2024)
○MRI情報学(2024)
○臨床医学入門B(2024)
○X線CT情報学(2024)
○臨床医学入門A(2024)
○臨床医学各論 栄養・消化器学(2022)


