HONDA, Masao - Directory of Researchers at Kanazawa University

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last modified：2024/11/22

Professor　HONDA, Masao

Basic
Research
Education
Social Contribution

Faculty, Affiliation

Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Health Sciences, Graduate School of Medical Science
Division of Health Sciences，Graduate School of Medical Science
Department of Laboratory Sciences，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Academic Background

Career

Kanazawa University
Kanazawa University
Kanazawa University
Kanazawa University
Kanazawa University(2007/07/01-)

Year & Month of Birth

Academic Society

Award

Specialities

Gastroenterology、、Immunology、

Speciality Keywords

Liver Disease

Research Themes

Viral Hepatitis

NASH

Hepatokine

Hepatic fibrosis

Molecular biology of HCC

Tumor immunity

Books

　Yamashita T, Honda M, Kaneko S.　Cancer Stem Cells - The Cutting Edge 　InTech　2011
　Yamashita T, Honda M, Kaneko S.　Molecular Genetics of Liver Neoplasia 　Springer　2011
　Honda M, Kaneko S.　New Perspectives in Cancer Research and Therapy 　Research Signpost　2005
　Honda M, Kaneko S.　Recent Res. Devel. Experimental Med 　Tranworld Research Network　2004
　Honda M, Sakai A, Kaneko S, Kobayashi K.　Frontiers in Hepatology, Liver cirrhosis　Springer-Verlag　2001

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　Honda M, Geoff Abell, Kaneko S, Kobayashi K, Stanley M. Lemon.　Frontiers in Hepatology, HCV and Related Liver Deseases 　Springer-Verlag　1999
　本多政夫, 村居和寿　モデル動物の作製と利用　循環器疾患2021　上巻　エル・アイ・シー　2021/09/09
　本多政夫, 金子周一.　実験医学増刊　炎症-全体像を知り慢性疾患を制御する炎症シグナル、免疫細胞のダイナミズムからがん・糖尿病などの発症機序と治療標的まで　羊土社　2014
　本多政夫, 金子周一.　分子消化器病　特集　消化器疾患におけるsmall RNAの役割を解明する　先端医学社　2015
　本多政夫, 金子周一.　Hepatology Practice 3　C型肝炎の診療を極める　基本から最前線まで　文光堂　2014
　本多政夫, 金子周一.　Hepatology Practice 3　C型肝炎の診療を極める　基本から最前線まで　文光堂　2014
　本多政夫, 金子周一.　Hepatology Practice 4　難治性肝疾患の診療を極める　基本から最前線まで　文光堂　2014
　本多政夫.　Hepatology Practice 1　B型肝炎の診療を極める　文光堂　2013
　本多政夫, 金子周一.　カラー消化器病　基礎と臨床　西村書店　2013
　本多政夫, 金子周一.　肝疾患 Review 2012-2013　日本メディカルセンター　2012
　本多政夫, 山下太郎, 上田晃之, 川口和紀, 西野隆平, 鷹取元, 皆川宏貴, 金子周一.　DNAチップ活用テクノロジーと応用」　シーエムシー出版　2006
　本多政夫, 山下太郎, 川口和紀, 金子周一.　肝疾患Review 2006-2007　日本メディカルセンター　2006
　本多政夫, 山下太郎, 川口和紀, 代田幸博, 金子周一.　　消化器疾患最新の治療2005-2006　南江堂　2005
　本多政夫, 上田晃之, 金子周一.　消化器病学の進歩2005-モノグラフ-　日本消化器病学会　2005
　本多政夫, 山下太郎, 代田幸博, 金子周一.　先端医療シリーズ25　肝・胆・膵疾患の最新医療　先端医療技術研究所　2003
　本多政夫, 舘野誠, 山下太郎, 金子周一　C型慢性肝炎治療の新たなストラテジー　-インターフェロン治療の今後-　先端医学社　2003
　本多政夫, 金子周一　メディコピア（39）ウイルス肝炎-最前線　富士レビオ社　1999
　鍛治恭介, 金子周一, 寺崎修一, 斉藤孝仁, 土山智也, 酒井佳夫, 蓑内慶次, 水腰英四郎, 大野秀棋, 小浦隆義, 酒井明人, 中本安成, 本多政夫, 河合博志, 松下栄紀, 卜部　健, 小林健一.　肝硬変の成因別実態1998　中外医学社　1999
　本多政夫, 竹内正勇, 稲垣　豊, 金子周一, 鵜浦雅志, 小林健一. 編集田中　慧, 小原道法. 　C型肝炎から肝細胞へ　メジカルビュウー社　1994

Papers

　Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET.　Takayoshi Shirasaki,Satoshi Yamagoe,Tetsuro Shimakami,Kazuhisa Murai,Ryu Imamura,Kiyo-Aki Ishii,Hiroaki Takayama,Yukako Matsumoto,Natsumi Tajima-Shirasaki,Naoto Nagata,Ryogo Shimizu,Souma Yamanaka,Atsushi Abe,Hitoshi Omura,Kazunori Kawaguchi,Hikari Okada,Taro Yamashita,Tomoki Yoshikawa,Kazuhiro Takimoto,Motoko Taharaguchi,Shogo Takatsuka,Yoshitsugu Miyazaki,Toshikatsu Tamai,Yamato Tanabe,Makoto Kurachi,Yasuhiko Yamamoto,Shuichi Kaneko,Kunio Matsumoto,Toshinari Takamura,Masao Honda　Nature communications　13　1　3176　2022/06/08
　Induction of selenoprotein P mRNA during hepatitis C virus infection inhibits RIG-I-mediated antiviral immunity.　Kazuhisa Murai, Masao Honda, Takayoshi Shirasaki, Tetsuro Shimakami, Hitoshi Omura, Hirofumi Misu, Yuki Kita, Yumie Takeshita, Kiyo-aki Ishii, Toshinari Takamura, Takeshi Urabe, Ryogo Shimizu, Hikari Okada, Taro Yamashita, Yoshio Sakai, Shuichi Kaneko 　Cell Host & Microbe　25　4　588-601　2019/04/10
　Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid.　Qin XY, Suzuki H, Honda M, Okada H, Kaneko S, Inoue I, Ebisui E, Hashimoto K, Carninci P, Kanki K, Tatsukawa H, Ishibashi N, Masaki T, Matsuura T, Kagechika H, Toriguchi K, Hatano E, Shirakami Y, Shiota G, Shimizu M, Moriwaki H, Kojima S.　Proc Natl Acad Sci USA　115　19　4969-4974　2018/05/08
　Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.　Misu H, Takayama H, Saito Y, Mita Y, Kikuchi A, Ishii KA, Chikamoto K, Kanamori T, Tajima N, Lan F, Takeshita Y, Honda M, Tanaka M, Kato S, Matsuyama N, Yoshioka Y, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, Kaneko S, Takamura T.　Nat Med.　23　4　508-516　2017/04/01
　Malnutrition impairs interferon signaling through mTOR and FoxO pathways in patients with chronic hepatitis C.　Honda M, Takehana K, Sakai A, Tagata Y, Shirasaki T, Nishitani S, Muramatsu T, Yamashita T, Nakamoto Y, Mizukoshi E, Sakai Y, Yamashita T, Nakamura M, Shimakami T, Yi M, Lemon SM, Suzuki T, Wakita T, Kaneko S; Hokuriku Liver Study Group.　Gastroenterology　141　1　128-40　2011/07/01

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　Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C.　Honda M, Sakai A, Yamashita T, Nakamoto Y, Mizukoshi E, Sakai Y, Yamashita T, Nakamura M, Shirasaki T, Horimoto K, Tanaka Y, Tokunaga K, Mizokami M, Kaneko S; Hokuriku Liver Study Group　Gastroenterology　139　2　499-509　2010/08
　Risk of hepatitis C virus infections through household contact with chronic carriers: Analysis of nucleotide sequences　Masao Honda,Shuichi Kaneko,Masashi Unoura,Kenichi Kobayashi,Seishi Murakami　Hepatology　17　6　971　1993/06　
　Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus　Hervé Lerat,Masao Honda,Michael R. Beard,Kim Loesch,Jiaren Sun,Yan Yang,Michiari Okuda,Rainer Gosert,Shu-Yuan Xiao,Steven A. Weinman,Stanley M. Lemon　Gastroenterology　122　2　352　2002
　Cell cycle regulation of hepatitis C virus internal ribosomal entry site-directed translation　M Honda,S Kaneko,E Matsushita,K Kobayashi,GA Abell,SM Lemon　GASTROENTEROLOGY　118　1　152　2000/01
　alpha-Fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis　HF Kawai,S Kaneko,M Honda,Y Shirota,K Kobayashi　HEPATOLOGY　33　3　676　2001/03
　Differential gene expression between chronic hepatitis B and C hepatic lesion　M Honda,S Kaneko,H Kawai,Y Shirota,K Kobayashi　GASTROENTEROLOGY　120　4　955　2001/03
　An infectious molecular clone of a Japanese genotype 1b hepatitis C virus　Michael R. Beard,Geoffrey Abell,Masao Honda,Anthony Carroll,Margaret Gartland,Berwyn Clarke,Koyu Suzuki,Robert Lanford,David V. Sangar,Stanley M. Lemon　Hepatology　30　1　316　1999
　Enhanced antitumor effects of a bicistronic adenovirus vector expressing both herpes simplex virus thymidine kinase and monocyte chemoattractant protein-1 against hepatocellular carcinoma　Tomoya Tsuchiyama,Shuichi Kaneko,Yasunari Nakamoto,Yoshio Sakai,Masao Honda,Naofumi Mukaida,Kenichi Kobayashi　Cancer Gene Therapy　10　4　260　2003/04　
　Sequence analysis of putative structural regions of hepatitis C virus isolated from 5 Japanese patients with hepatocellular carcinoma　M. Honda,S. Kaneko,M. Unoura,K. Kobayashi,S. Murakami　Archives of Virology　128　1-2　163　1993/03
　Natural variation in translational activities of the 5' nontranslated RNAs of hepatitis C virus genotypes 1a and 1b: Evidence for a long-range RNA- RNA interaction outside of the internal ribosomal entry site　Masao Honda,Rene Rijnbrand,Geoff Abell,Desok Kim,Stanley M. Lemon　Journal of Virology　73　6　4941　1999
　A phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap- independent viral translation　Masao Honda,Michael R. Beard,Li-Hua Ping,Stanley M. Lemon　Journal of Virology　73　2　1165　1999
　Sequence analysis of putative structural regions of hepatitis C virus isolated from 5 patients　Masao Honda　Kanzo　32　12　1101　1991
　INVOLVEMENT OF TYPE-II DNA TOPOISOMERASE IN ILLEGITIMATE RECOMBINATION IN ESCHERICHIA-COLI - ANALYSES OF THE PARTIAL DIPLOID OF PHAGE-T4 AND THE SPECIALIZED TRANSDUCING PARTICLES OF PHAGE-LAMBDA　H IKEDA,M KUMAGAI,T YAMASHITA,M HONDA　MOLECULAR BIOLOGY OF DNA TOPOISOMERASES AND ITS APPLICATION CHEMOTHERAPY　49　1993
　Quasispecies of hepatitis C virus in serum and in three different parts of the liver of patients with chronic hepatitis　A Sakai,S Kaneko,M Honda,E Matsushita,K Kobayashi　HEPATOLOGY　30　2　556　1999/08
　Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells　M Honda,S Kaneko,T Shimazaki,E Matsushita,K Kobayashi,LH Ping,HC Zhang,SM Lemon　HEPATOLOGY　31　6　1351　2000/06
　A case of hepatitis occuring one year after allogenic bone marrow transplantation; Is it a form of hepatic garft-versus-host disease?　Naoki Ikeda,Masashi Unoura,Masao Honda,Mitsuhiro Terada,Eiki Matsushita,Yutaka Inagaki,Shuichi Kaneko,Ken-ichi Kobayashi,Sintarou Shiobara,Tamotsu Matsuda,Akitaka Nonomura,Yasuni Nakanuma　Kanzo　31　12　1452　1990
　Hepatic Steatosis and Hepatocellular Carcinoma in Hepatitis C Transgenic Mice　Stanley M. Lemon,Herve Lerat,Masao Honda,Kim Loesch,Brian West,Michiari Okuda,Shu-Yuan Xiao,Michael Beard,Yan Yang,Steven A. Weinman　Acta Hepatologica Japonica　41　A27　2000
　Approach to establishing a liver targeting gene therapeutic vector using naturally occurring defective hepatitis B viruses devoid of immunogenic T cell epitope　Liqun Wang,Shuichi Kaneko,Masao Honda,Kenichi Kobayashi　Virus Research　85　2　187　2002/05/10
　Detection of hepatitis B virus DNA in sera from patients with chronic hepatitis B virus infection by DNA microarray method　K Kawaguchi,S Kaneko,M Honda,HF Kawai,Y Shirota,K Kobayashi　JOURNAL OF CLINICAL MICROBIOLOGY　41　4　1701　2003/04
　Detection of the putative E2 protein of hepatitis C virus in human liver　Yasunari Nakamoto,Shuichi Kaneko,Masao Honda,Masashi Unoura,Jaehun Cheong,Akihisa Harada,Kouji Matsushima,Kenichi Kobayashi,Seishi Murakami　Journal of Medical Virology　42　4　374　1994
　Sequence comparisons for a hepatitis C virus genome RNA isolated from a patient with liver cirrhosis　Masao Honda,Shuichi Kaneko,Masashi Unoura,Kenichi Kobayashi,Seishi Murakami　Gene　120　2　317　1992/10
　B-Cell epitopes in hypervariable region 1 of hepatitis C virus obtained from patients with chronic persistent hepatitis　Yasunari Nakamoto,Shuichi Kaneko,Hideki Ohno,Masao Honda,Masashi Unoura,Seishi Murakami,Kenichi Kobayashi　Journal of Medical Virology　50　1　35　1996/09
　Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays　Y Shirota,S Kaneko,M Honda,HF Kawai,K Kobayashi　HEPATOLOGY　33　4　832　2001/04
　A case of recurrent ischemic colitis associated with barium enema study　Masao Honda,Manabu Yonejima,Rieko Saiki,Taisei Sawada,Yoshirou Kitano　Nippon Shokakibyo Gakkai Zasshi　89　10　2619　1992
　Natural variation in translational activities of the 5 ' nontranslated RNAs of genotypes 1a and 1b hepatitis C virus: Evidence for a long range RNA-RNA interaction outside of the internal ribosomal entry segment　M Honda,G Abell,S Kaneko,K Kobayashi,SM Lemon　HCV AND RELATED LIVER DISEASES　59　1999
　Degree of diversity of hepatitis C virus quasispecies and progression of liver disease　Masao Honda,Shuichi Kaneko,Akito Sakai,Masashi Unoura,Seishi Murakami,Kenichi Kobayashi　Hepatology　20　5　1144　1994/11　
　Inhibition of internal ribosomal entry site-directed translation of HCV by recombinant IFN-alpha correlates with a reduced La protein.　Takeo Shimazaki,Masao Honda,Shuichi Kaneko,Kenichi Kobayashi　Hepatology (Baltimore, Md.)　35　1　199　2002/01
　Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells　LQ Wang,S Kaneko,M Kagaya,H Ohno,M Honda,K Kobayashi　JOURNAL OF GASTROENTEROLOGY　37　6　449　2002/06
　A case of treatment of advanced hepatocellular carcinoma with hemobilia with a combination therapy consisting of intraarterial chemotherapy and injection of interferon　Yoshiko Takata,Tatsuya Yamashita,Akiyoshi Shimatani,Noriho Iida,Kuniaki Arai,Kazuya Kitamura,Takashi Kagaya,Taro Yamashita,Yoshio Sakai,Hirokazu Tsuji,Eishiro Mizukoshi,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko,Tamotsu Koyama　Acta Hepatologica Japonica　46　6　365　2005
　Genome-wide transcriptome mapping analysis identifies organ-specific gene expression patterns along human chromosomes　T Yamashita,M Honda,H Takatori,R Nishino,N Hoshino,S Kaneko　GENOMICS　84　5　867　2004/11
　Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based comparative genomic hybridization.　Kawaguchi K,Honda M,Yamashita T,Shirota Y,Kaneko S　Biochemical and biophysical research communications　329　1　370　2005/04
　Genes for systemic vascular complications are differentially expressed in the livers of Type 2 diabetic patients　T Takamura,M Sakurai,T Ota,H Ando,M Honda,S Kaneko　DIABETOLOGIA　47　4　638　2004/04
　Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes　H. Misu,T. Takamura,N. Matsuzawa,A. Shimizu,T. Ota,M. Sakurai,H. Ando,K. Arai,T. Yamashita,M. Honda,T. Yamashita,S. Kaneko　DIABETOLOGIA　50　2　268　2007/02　
　[A case of nasal metastasis of hepatocellular carcinoma that was treated under transcatheter arterial embolization for control nasal bleeding].　Komura T,Kagaya T,Tateno M,Arai K,Yamashita T,Yamashita T,Tsuji H,Mizukoshi E,Sakai A,Kaji K,Nakamoto Y,Honda M,Kaneko S,Matsui O　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　102　8　1055　2005/08　
　A case of congenital absence of portal vein with focal nodular hyperplasia (FNH) and multiple FNH-like lesions in the liver　SHIGEYAMA Isamu,YAMASHITA Tatsuya,ARAI Kuniaki,IIDA Hiroshi,KAKINOKI Kaheita,KAWAGUCHI Kazunori,KITAMURA Kazuya,KAGAYA Takashi,SAKAI Yoshio,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,MATSUI Osamu,NAKANUMA Yasuni　Kanzo　48　3　102　2007/03/25
　A case of portopulmonary hypertension successfully treated by balloon-occluded retrograde transvenous obliteration and home oxygen therapy　YAMAMOTO Kanako,KAWAGUCHI Kazunori,KAKINOKI Kaheita,KITAMURA Kazuya,ARAI Kuniaki,IIDA Hiroshi,KAGAYA Takashi,SAKAI Yoshio,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,HONDA Masao,NAKAMOTO Yasunari,TAKAMURA Masayuki,MATSUI Osamu,KANEKO Shuichi　Kanzo　48　7　322　2007/07/25
　Pure red cell aplasia associated with concomitant use of mycophenolate mofetil and ribavirin in post-transplant recurrent hepatitis C.　Hodo Y,Tsuji K,Mizukoshi E,Yamashita T,Sakai A,Nakamoto Y,Honda M,Kaneko S　Transplant international : official journal of the European Society for Organ Transplantation　19　2　170　2006/02
　Differential gene expression profiles in stage I primary biliary cirrhosis.　Honda M,Kawai H,Shirota Y,Yamashita T,Kaneko S　The American journal of gastroenterology　100　9　2019　2005/09
　Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.　Shimakami T,Honda M,Kusakawa T,Murata T,Shimotohno K,Kaneko S,Murakami S　Journal of virology　80　7　3332　2006/04
　Genomics research in the liver. 2. Molecule pathogenesis of chronic hepatitis.　Honda M,Kaneko S　Kanzo　46　10　586　2005/10/25　
　La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation.　Masao Honda,Takeo Shimazaki,Shuichi Kaneko　Gastroenterology　128　2　449　2005/02
　cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation.　Honda M,Kawai H,Shirota Y,Yamashita T,Takamura T,Kaneko S　Journal of autoimmunity　25　2　133　2005/09
　The development and clinical features of splenic aneurysm associated with liver cirrhosis　Hajime Sunagozaka,Hirokazu Tsuji,Eishiro Mizukoshi,Kuniaki Arai,Takashi Kagaya,Tatsuya Yamashita,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko　Liver International　26　3　291　2006/04
　Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study　Tatsuya Yamashita,Kuniaki Arai,Akito Sakai,Eishiro Mizukoshi,Yoshio Sakai,Takashi Kagaya,Yasunari Nakamoto,Masao Honda,Takashi Wada,Hitoshi Yokoyama,Shuichi Kaneko　Hepatology Research　36　3　167　2006/11
　Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical gaussian model　Sachiyo Aburatani,Fuyan Sun,Shigeru Saito,Masao Honda,Shu-Ichi Kaneko,Katsuhisa Horimoto　Eurasip Journal on Bioinformatics and Systems Biology　2007　2007
　Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C　Masao Honda,Taro Yamashita,Teruyuki Ueda,Hajime Takatori,Ryuhei Nishino,Shuichi Kaneko　HEPATOLOGY　44　5　1122　2006/11
　Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy　Makoto Tateno,Masao Honda,Takashi Kawamura,Hiroyuki Honda,Shuichi Kaneko　JOURNAL OF INFECTIOUS DISEASES　195　2　255　2007/01
　Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon　Nobuhiko Hiraga,Michio Imamura,Masataka Tsuge,Chiemi Noguchi,Shoichi Takahashi,Eiji Iwao,Yoshifumi Fujimoto,Hiromi Abe,Toshiro Maekawa,Hidenori Ochi,Chise Tateno,Katsutoshi Yoshizato,Akihito Sakai,Yoshio Sakai,Masao Honda,Shuichi Kaneko,Takaji Wakita,Kazuaki Chayama　FEBS LETTERS　581　10　1983　2007/05
　Ephrin-A1 expression contributes to the malignant characteristics of alpha- fetoprotein producing hepatocellular carcinoma　H Iida,M Honda,HF Kawai,T Yamashita,Y Shirota,BC Wang,H Miao,S Kaneko　GUT　54　6　843　2005/06
　A case of combined hepatocelluar and cholangiocarcinoma in young man ; rapidly progressed and spontaneously ruptured after chemotherapy　TAKATORI Hajime,YAMASHITA Tatsuya,KAGAYA Takashi,TSUJI Hirokazu,MIZUKOSHI Eishiro,KAJI Kyousuke,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi　Kanzo　44　9　471　2003/09　
　Genome-wide analysis of gene expression in hepatocellular carcinoma　T Yamashita,S Kaneko,M Honda,K Kobayashi　STEM CELL AND LIVER REGENERATION　74　2004
　Successful Treatment for Autoimmune Hepatitis Complicated with Hepatocellular Carcinoma by Chemotherapy : A report of a case　MIZUNO Hideki,YAMASHITA Tatsuya,YAMASHITA Taro,KAGAYA Takashi,MIZUKOSHI Eishiro,TSUJI Hirokazu,KAJI Kyosuke,NAKAMOTO Yasunari,HONDA Masao,KANEKO Syuichi　Kanzo　45　2　116　2004/02　
　An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C　Kyosuke Kaji,Satoshi Yoshida,Nobuo Nagata,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Yasuhiko Kojima,Shuichi Kaneko　Journal of Gastroenterology　39　9　873　2004/09
　Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes　Toshinari Takamura,Masao Honda,Yoshio Sakai,Hitoshi Ando,Akiko Shimizu,Tsuguhito Ota,Masaru Sakurai,Hirofumi Misu,Seiichiro Kurita,Naoto Matsuzawa-Nagata,Masahiro Uchikata,Seiji Nakamura,Ryo Matoba,Motohiko Tanino,Ken-ichi Matsubara,Shuichi Kaneko　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　361　2　379　2007/09
　A case of metastatic gallbladder tumor of the hepatocellular carcinoma　TERASHIMA Takeshi,YAMASHITA Tatsuya,ARAI Kuniaki,KAKINOKI Kaheita,KAGAYA Takashi,SAKAI Yoshio,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,OJIMA Toshihiko,KITAGAWA Hirohisa,KAYAHARA Masato,OOTA Tetsuo,ZEN You,NAKANUMA Yasuni　Kanzo　48　8　363　2007/08/25
　A non-Hodgkin lymphoma patient with reactivation of HBV during chemotherapy and emergence of a YMDD-motif mutant on lamivudine, eventually controlled by adfovil dipovoxil　TERASHIMA Takeshi,ARAI Kuniaki,KOMURA Takuya,IIDA Hiroshi,KAGAYA Takashi,SAKAI Yoshio,YAMASHITA Tatsuya,SAKAI Akito,MIZUKOSHI Eishiro,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,ZEN You,NAKANUMA Yasuni　Kanzo　48　7　309　2007/07/25
　Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet　Naoto Matsuzawa,Toshinari Takamura,Seiichiro Kurita,Hirofumi Misu,Hitoshi Ando,Masayoshi Yokoyama,Masao Honda,Yoh Zen,Yasuni Nakanuma,Ken-Ichi Miyamoto,Shuichi Kaneko　HEPATOLOGY　46　5　1392　2007/11
　A case of primary biliary cirrhosis with progressive jaundice due to Basedow's disease　SHIMAKAMI Tetsuro,YAMASHITA Tatsuya,SAKAI Yoshio,ARAI Kuniaki,IIDA Hiroshi,KITAMURA Kazuya,KAGAYA Takashi,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi　Kanzo　48　9　452　2007/09/25
　Detection of network structure changes by graphical chain modeling: a case study of hepatitis C virus-related hepatocellular carcinoma　Shigeru Saito,Masao Honda,Shu-ichi Kaneko,Katsuhisa Horimoto　PROCEEDINGS OF THE 48TH IEEE CONFERENCE ON DECISION AND CONTROL, 2009 HELD JOINTLY WITH THE 2009 28TH CHINESE CONTROL CONFERENCE (CDC/CCC 2009)　5624　2009
　Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma.　Minagawa H,Honda M,Miyazaki K,Tabuse Y,Teramoto R,Yamashita T,Nishino R,Takatori H,Ueda T,Kamijo K,Kaneko S　Biochemical and biophysical research communications　366　1　186　2008/02
　Detection of network structure changes by graphical chain modeling: A case study of hepatitis C virus-related hepatocellular carcinoma　Shigeru Saito,Masao Honda,Shu-Ichi Kaneko,Katsuhisa Horimoto　Proceedings of the IEEE Conference on Decision and Control　5624　2009
　Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients.　Sakai Y,Honda M,Fujinaga H,Tatsumi I,Mizukoshi E,Nakamoto Y,Kaneko S　Cancer research　68　24　10267　2008/12
　Application of Serial Analysis of Gene Expression in Cancer Research　T. Yamashita,M. Honda,S. Kaneko　Current Pharmaceutical Biotechnology　9　5　375　2008/10/01　
　Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma.　Yamashita T,Honda M,Takatori H,Nishino R,Minato H,Takamura H,Ohta T,Kaneko S　Journal of hepatology　50　1　100　2009/01
　Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma.　Nishino R,Honda M,Yamashita T,Takatori H,Minato H,Zen Y,Sasaki M,Takamura H,Horimoto K,Ohta T,Nakanuma Y,Kaneko S　Journal of hepatology　49　2　207　2008/08
　Comparative analysis of proteome and transcriptome in human hepatocellular carcinoma using 2D-DIGE and SAGE.　Minagawa H,Yamashita T,Honda M,Tabuse Y,Kamijo K,Tsugita A,Kaneko S　The protein journal　27　7-8　409　2008/12
　A case of refractory hepatic hydrothorax complicated with spontaneous bacterial empyema in a type C liver cirrhosis patient, successfully treated with transjugular intrahepatic portosystemic shunt　SHUGO Haruhiko,KAGAYA Takashi,OISHI Naoki,ARAI Kuniaki,KITAMURA Kazuya,SAKAI Yoshio,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,MATSUI Osamu　Kanzo　48　9　439　2007/09/25
　[Unresectable pancreatic cancer in the Hokuriku area].　Terashima T,Yamashita T,Arai K,Iida H,Kakinoki K,Kitamura K,Kagaya T,Sakai Y,Mizukosi E,Sakai A,Nakamoto Y,Honda M,Kaneko S　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　105　3　373　2008/03
　Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning.　Reiji Teramoto,Hirotaka Minagawa,Masao Honda,Kenji Miyazaki,Yo Tabuse,Ken'ichi Kamijo,Teruyuki Ueda,Shuichi Kaneko　Biochimica et biophysica acta　1784　5　764　2008/05
　Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity　Naoto Matsuzawa-Nagata,Toshinari Takamura,Hitoshi Ando,Seiji Nakamura,Seiichiro Kurita,Hirofumi Misu,Tsuguhito Ota,Masayoshi Yokoyama,Masao Honda,Ken-ichi Miyamoto,Shuichi Kaneko　METABOLISM-CLINICAL AND EXPERIMENTAL　57　8　1071　2008/08
　Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma　Eishiro Mizukoshi,Masao Honda,Kuniaki Arai,Tatsuya Yamashita,Yasunari Nakamoto,Shuichi Kaneko　JOURNAL OF HEPATOLOGY　49　6　946　2008/12
　Comprehensive gene expression analysis in hepatocellular carcinoma (HCC) by newly developed 5 '-end sage method and identification of novel up-regulated intronic transcript　Hodo Yuji,Hashimoto Shin-ichi,Deshimaru Shungo,Honda Masao,Yamashita Taro,Ueda Teruyuki,Matsushima Kouji,Kaneko Shuichi　HEPATOLOGY　46　4　798A　2007/10
　Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.　Oishi N,Shilagardi K,Nakamoto Y,Honda M,Kaneko S,Murakami S　Cancer science　98　10　1540　2007/10　
　Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis　Takuya Komura,Eishiro Mizukoshi,Yuki Kita,Masaru Sakurai,Yoshiko Takata,Kuniaki Arai,Tatsuya Yamashita,Tetsuo Ohta,Koichi Shimizu,Yasunari Nakamoto,Masao Honda,Toshinari Takamura,Shuichi Kaneko　AMERICAN JOURNAL OF GASTROENTEROLOGY　102　9　1939　2007/09
　Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection.　Taro Yamashita,Masao Honda,Shuichi Kaneko　Journal of gastroenterology and hepatology　26　6　960　2011/06
　Endothelial to Mesenchymal Transition via Transforming Growth Factor-beta 1/Smad Activation Is Associated with Portal Venous Stenosis in Idiopathic Portal Hypertension　Azusa Kitao,Yasunori Sato,Seiko Sawada-Kitamura,Kenichi Harada,Motoko Sasaki,Hiroyasu Morikawa,Susumu Shiomi,Masao Honda,Osamu Matsui,Yasuni Nakanuma　AMERICAN JOURNAL OF PATHOLOGY　175　2　616　2009/08
　Altered hepatic gene expression profiles associated with myocardial ischemia.　Ootsuji H,Honda M,Kaneko S,Usui S,Okajima M,Okada H,Sakai Y,Takamura T,Horimoto K,Takamura M　Circulation. Cardiovascular genetics　3　1　68　2010/02
　Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma.　Hodo Y,Hashimoto S,Honda M,Yamashita T,Suzuki Y,Sugano S,Kaneko S,Matsushima K　Genomics　95　4　217　2010/04　
　Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C　Masao Honda,Akito Sakai,Tatsuya Yamashita,Yasunari Nakamoto,Eishiro Mizukoshi,Yoshio Sakai,Taro Yamashita,Mikiko Nakamura,Takayoshi Shirasaki,Katsuhisa Horimoto,Yasuhito Tanaka,Katsushi Tokunaga,Masashi Mizokami,Shuichi Kaneko　GASTROENTEROLOGY　139　2　499　2010/08
　Differential gene expression profiling in blood from patients with digestive system cancers.　Honda M,Sakai Y,Yamashita T,Yamashita T,Sakai A,Mizukoshi E,Nakamoto Y,Tatsumi I,Miyazaki Y,Tanno H,Kaneko S,Hokuriku Liver,Study Group　Biochemical and biophysical research communications　400　1　7　2010/09　
　A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance　Hirofumi Misu,Toshinari Takamura,Hiroaki Takayama,Hiroto Hayashi,Naoto Matsuzawa-Nagata,Seiichiro Kurita,Kazuhide Ishikura,Hitoshi Ando,Yumie Takeshita,Tsuguhito Ota,Masaru Sakurai,Tatsuya Yamashita,Eishiro Mizukoshi,Taro Yamashita,Masao Honda,Ken-ichi Miyamoto,Tetsuya Kubota,Naoto Kubota,Takashi Kadowaki,Han-Jong Kim,In-Kyu Lee,Yasuhiko Minokoshi,Yoshiro Saito,Kazuhiko Takahashi,Yoshihiro Yamada,Nobuyuki Takakura,Shuichi Kaneko　CELL METABOLISM　12　5　483　2010/11
　Randomized, phase II study comparing interferon combined with hepatic arterial infusion of fluorouracil plus cisplatin and fluorouracil alone in patients with advanced hepatocellular carcinoma.　Tatsuya Yamashita,Kuniaki Arai,Hajime Sunagozaka,Teruyuki Ueda,Takeshi Terashima,Taro Yamashita,Eishiro Mizukoshi,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko　Oncology　81　5-6　281　2011
　Pre-treatment prediction of response to pegylated-Interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors.　Kurosaki M,Tanaka Y,Nishida N,Sugiyama M,Matsuura K,Asahina Y,Sugauchi F,Sakamoto N,Nakagawa M,Watanabe M,Sakai A,Honda M,Kaneko S,Ito K,Masaki N,Tokunaga K,Izumi N,Mizokami M　J Hepatol　54:439-448, 2011　3　439　2011
　Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C　Masao Honda,Kenji Takehana,Akito Sakai,Yusuke Tagata,Takayoshi Shirasaki,Shinobu Nishitani,Takahiko Muramatsu,Tatsuya Yamashita,Yasunari Nakamoto,Eishiro Mizukoshi,Yoshio Sakai,Taro Yamashita,Mikiko Nakamura,Tetsuro Shimakami,Minkyung Yi,Stanley M. Lemon,Tetsuo Suzuki,Takaji Wakita,Shuichi Kaneko　GASTROENTEROLOGY　141　1　128　2011/07
　Proposed treatment guidance on new anticancer agents for the treatment of hepatocellular carcinoma, 2010 up date : 2010 Health and Labour Sciences Research Grant Research Project on Emergency Measures to Overcome Hepatitis　KANEKO Shuichi,FURUSE Junji,KUDO Masatoshi,IKEDA Kenji,HONDA Masao,NAKAMOTO Yasunari,ONJI Morikazu,SHIOTA Goshi,YOKOSUKA Osamu,SAKAIDA Isao,TAKEHARA Tetsuo,UENO Yoshiyuki,HIROISHI Kazumasa,NISHIGUCHI Shuhei,MORIWAKI Hisataka,YAMAMOTO Kazuhide,SATA Michio,OBI Shuntaro,MIYAYAMA Shiro,IMAI Yukinori　Kanzo　52　8　532　2011/08/25　
　Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.　Tanaka Y,Kurosaki M,Nishida N,Sugiyama M,Matsuura K,Sakamoto N,Enomoto N,Yatsuhashi H,Nishiguchi S,Hino K,Hige S,Itoh Y,Tanaka E,Mochida S,Honda M,Hiasa Y,Koike A,Sugauchi F,Kaneko S,Izumi N,Tokunaga K,Mizokami M　Human molecular genetics　20　17　3507　2011/09
　Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma　Hajime Sunagozaka,Masao Honda,Taro Yamashita,Ryuhei Nishino,Hajime Takatori,Kuniaki Arai,Tatsuya Yamashita,Yoshio Sakai,Shuichi Kaneko　International Journal of Cancer　129　7　1576　2011/10/01
　A case report of S-1 monotherapy for advanced hepatocellular carcinoma　Tatsuya Yamashita,Kuniaki Arai,Takeshi Terashima,Hajime Sunagozaka,Tetsuro Shimakami,Taro Yamashita,Eishiro Mizukoshi,Akito Sakai,Masao Honda,Shuichi Kaneko　Japanese Journal of Cancer and Chemotherapy　39　9　1435　2012
　Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C　Yasuhito Tanaka,Nao Nishida,Masaya Sugiyama,Masayuki Kurosaki,Kentaro Matsuura,Naoya Sakamoto,Mina Nakagawa,Masaaki Korenaga,Keisuke Hino,Shuhei Hige,Yoshito Ito,Eiji Mita,Eiji Tanaka,Satoshi Mochida,Yoshikazu Murawaki,Masao Honda,Akito Sakai,Yoichi Hiasa,Shuhei Nishiguchi,Asako Koike,Isao Sakaida,Masatoshi Imamura,Kiyoaki Ito,Koji Yano,Naohiko Masaki,Fuminaka Sugauchi,Namiki Izumi,Katsushi Tokunaga,Masashi Mizokami　NATURE GENETICS　41　10　1105　2009/10
　ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C.　Sakamoto N,Tanaka Y,Nakagawa M,Yatsuhashi H,Nishiguchi S,Enomoto N,Azuma S,Nishimura-Sakurai Y,Kakinuma S,Nishida N,Tokunaga K,Honda M,Ito K,Mizokami M,Watanabe M　Hepatology research : the official journal of the Japan Society of Hepatology　40　11　1063　2010/11　
　MUCOSAL FINDINGS OF THE SMALL INTESTINE IN PATIENTS WITH PORTAL HYPERTENSION DUE TO LIVER CIRROSIS : A CAPSULE ENDOSCOPY STUDY　MIZUNO Hideki,KAGAYA Takashi,OOISHI Naoki,TAKATORI Hajime,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi　Gastroenterological Endoscopy　53　6　1600　2011/06/20　
　Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma.　Shunsuke Ura,Masao Honda,Taro Yamashita,Teruyuki Ueda,Hajime Takatori,Ryuhei Nishino,Hajime Sunakozaka,Yoshio Sakai,Katsuhisa Horimoto,Shuichi Kaneko　Hepatology (Baltimore, Md.)　49　4　1098　2009/04
　Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.　Eishiro Mizukoshi,Yasunari Nakamoto,Kuniaki Arai,Tatsuya Yamashita,Akito Sakai,Yoshio Sakai,Takashi Kagaya,Taro Yamashita,Masao Honda,Shuichi Kaneko　Hepatology (Baltimore, Md.)　53　4　1206　2011/04
　Heterogeneity of Liver Cancer Stem Cells　Taro Yamashita,Masao Honda,Shuichi Kaneko　Molecular Genetics of Liver Neoplasia　301　2010　
　Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C.　Masao Honda,Mikiko Nakamura,Makoto Tateno,Akito Sakai,Tetsuro Shimakami,Takayoshi Shirasaki,Tatsuya Yamashita,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko　Journal of hepatology　53　5　817　2010/11
　La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication.　Shirasaki T,Honda M,Mizuno H,Shimakami T,Okada H,Sakai Y,Murakami S,Wakita T,Kaneko S　The Journal of infectious diseases　202　1　75　2010/07
　[Two cases of a nonfunctioning pancreatic endocrine tumor found on a medical checkup].　Nio K,Shimakami T,Yamashita T,Kagaya T,Sakai Y,Yamashita T,Mizukoshi E,Sakai A,Nakamoto Y,Honda M,Kaneko S,Kitagawa H,Kayahara M,Ohta T,Zen Y　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　106　4　560　2009/04
　CD14(+) Monocytes Are Vulnerable and Functionally Impaired Under Endoplasmic Reticulum Stress in Patients With Type 2 Diabetes　Takuya Komura,Yoshio Sakai,Masao Honda,Toshinari Takamura,Kouji Matsushima,Shuichi Kaneko　DIABETES　59　3　634　2010/03
　Panel discussion: HCV infection and host factor, IL28B in particular　Yasuhito Tanaka,Katsushi Tokunaga,Masao Honda,Norio Akuta,Yasuhiro Asahina,Masashi Mizokami　Acta Hepatologica Japonica　51　7　327　2010/09/01　
　Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation.　Yamashita T,Honda M,Nio K,Nakamoto Y,Yamashita T,Takamura H,Tani T,Zen Y,Kaneko S　Cancer research　70　11　4687　2010/06　
　EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features.　Yamashita T,Ji J,Budhu A,Forgues M,Yang W,Wang HY,Jia H,Ye Q,Qin LX,Wauthier E,Reid LM,Minato H,Honda M,Kaneko S,Tang ZY,Wang XW　Gastroenterology　136　3　1012　2009/03
　Association of interleukin-28B genotype and hepatocellular carcinoma recurrence in patients with chronic hepatitis C.　Hodo Y,Honda M,Tanaka A,Nomura Y,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Sakai A,Sasaki M,Nakanuma Y,Moriyama M,Kaneko S　Clinical cancer research : an official journal of the American Association for Cancer Research　19　7　1827　2013/04
　Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma.　Yamashita T,Honda M,Nakamoto Y,Baba M,Nio K,Hara Y,Zeng SS,Hayashi T,Kondo M,Takatori H,Yamashita T,Mizukoshi E,Ikeda H,Zen Y,Takamura H,Wang XW,Kaneko S　Hepatology (Baltimore, Md.)　57　4　1484　2013/04
　Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma.　Danning He,Zhi-Ping Liu,Masao Honda,Shuichi Kaneko,Luonan Chen　Journal of molecular cell biology　4　3　140　2012/06
　MicroRNA-27a Regulates Lipid Metabolism and Inhibits Hepatitis C Virus Replication in Human Hepatoma Cells　Takayoshi Shirasaki,Masao Honda,Tetsuro Shimakami,Rika Horii,Taro Yamashita,Yoshio Sakai,Akito Sakai,Hikari Okada,Risa Watanabe,Seishi Murakami,MinKyung Yi,Stanley M. Lemon,Shuichi Kaneko　JOURNAL OF VIROLOGY　87　9　5270　2013/05
　Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model.　Akihiro Seki,Yoshio Sakai,Takuya Komura,Alessandro Nasti,Keiko Yoshida,Mami Higashimoto,Masao Honda,Soichiro Usui,Masayuki Takamura,Toshinari Takamura,Takahiro Ochiya,Kengo Furuichi,Takashi Wada,Shuichi Kaneko　Hepatology (Baltimore, Md.)　58　3　1133　2013/09
　microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection.　Spaniel C,Honda M,Selitsky SR,Yamane D,Shimakami T,Kaneko S,Lanford RE,Lemon SM　PloS one　8　10　e76867　2013
　Expression of chondroitin-glucuronate C5-epimerase and cellular immune responses in patients with hepatocellular carcinoma.　Eishiro Mizukoshi,Kazumi Fushimi,Kuniaki Arai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko　Liver international : official journal of the International Association for the Study of the Liver　32　10　1516　2012/11
　Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma.　Masao Honda,Taro Yamashita,Tatsuya Yamashita,Kuniaki Arai,Yoshio Sakai,Akito Sakai,Mikiko Nakamura,Eishiro Mizukoshi,Shuichi Kaneko　BMC cancer　13　191　2013/04/15
　Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update　Shuichi Kaneko,Junji Furuse,Masatoshi Kudo,Kenji Ikeda,Masao Honda,Yasunari Nakamoto,Morikazu Onchi,Goshi Shiota,Osamu Yokosuka,Isao Sakaida,Tetsuo Takehara,Yoshiyuki Ueno,Kazumasa Hiroishi,Shuhei Nishiguchi,Hisataka Moriwaki,Kazuhide Yamamoto,Michio Sata,Shuntaro Obi,Shiro Miyayama,Yukinori Imai　HEPATOLOGY RESEARCH　42　6　523　2012/06
　Association of changes in the gene expression profile of blood cells with the local tumor inflammatory response in a murine tumor model.　Sakai Y,Tatsumi I,Higashimoto M,Seki A,Nasti A,Yoshida K,Kawaguchi K,Wada T,Honda M,Komura T,Kaneko S　Biochemical and biophysical research communications　428　1　36　2012/11
　Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.　Minoru Nakamura,Nao Nishida,Minae Kawashima,Yoshihiro Aiba,Atsushi Tanaka,Michio Yasunami,Hitomi Nakamura,Atsumasai Komori,Makoto Nakamuta,Mikio Zeniya,Etsuko Hashimoto,Hiromasa Ohira,Kazuhide Yamamoto,Morikazu Onji,Shuichi Kaneko,Masao Honda,Satoshi Yamagiwa,Kazuhiko Nakao,Takafumi Ichida,Hajime Takikawa,Masataka Seike,Takeji Umemura,Yoshiyuki Ueno,Shotaro Sakisaka,Kentaro Kikuchi,Hirotoshi Ebinuma,Noriyo Yamashiki,Sumito Tamura,Yasuhiko Sugawara,Akira Mori,Shintaro Yagi,Ken Shirabe,Akinobu Taketomi,Kuniaki Arai,Kyoko Monoe,Tatsuki Ichikawa,Makiko Taniai,Yasuhiro Miyake,Teru Kumagi,Masanori Abe,Kaname Yoshizawa,Satoru Joshita,Shinji Shimoda,Koichi Honda,Hiroki Takahashi,Katsuji Hirano,Yasuaki Takeyama,Kenichi Harada,Kiyoshi Migita,Masahiro Ito,Hiroshi Yatsuhashi,Nobuyoshi Fukushima,Hajime Ota,Tatsuji Komatsu,Takeo Saoshiro,Jinya Ishida,Hirotsugu Kouno,Hirotaka Kouno,Michiyasu Yagura,Masakazu Kobayashi,Toyokichi Muro,Naohiko Masaki,Keiichi Hirata,Yukio Watanabe,Yoko Nakamura,Masaaki Shimada,Noboru Hirashima,Toshiki Komeda,Kazuhiro Sugi,Michiaki Koga,Keisuke Ario,Eiichi Takesaki,Yoshihiko Maehara,Shinji Uemoto,Norihiro Kokudo,Hirohito Tsubouchi,Masashi Mizokami,Yasuni Nakanuma,Katsushi Tokunaga,Hiromi Ishibashi　American journal of human genetics　91　4　721　2012/10/05
　A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma　Takuji Okusaka,Hiroshi Kasugai,Hiroshi Ishii,Masatoshi Kudo,Michio Sata,Katsuaki Tanaka,Yasukazu Shioyama,Kazuaki Chayama,Hiromitsu Kumada,Masaharu Yoshikawa,Toshihito Seki,Hidetugu Saito,Naoaki Hayashi,Keiko Shiratori,Kiwamu Okita,Isao Sakaida,Masao Honda,Yukio Kusumoto,Takuya Tsutsumi,Kenji Sakata　Investigational New Drugs　30　5　2015　2012/10
　No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations　Hiromi Sawai,Nao Nishida,Nao Nishida,Hamdi Mbarek,Koichi Matsuda,Yoriko Mawatari,Megumi Yamaoka,Shuhei Hige,Jong Hon Kang,Koichi Abe,Satoshi Mochida,Masaaki Watanabe,Masayuki Kurosaki,Yasuhiro Asahina,Namiki Izumi,Masao Honda,Shuichi Kaneko,Eiji Tanaka,Kentaro Matsuura,Yoshito Itoh,Eiji Mita,Masaaki Korenaga,Keisuke Hino,Yoshikazu Murawaki,Yoichi Hiasa,Tatsuya Ide,Kiyoaki Ito,Masaya Sugiyama,Sang H. Ahn,Kwang Hyub Han,Jun Y. Park,Man Fung Yuen,Yusuke Nakamura,Yasuhito Tanaka,Masashi Mizokami,Katsushi Tokunaga　BMC Medical Genetics　13　47　2012/06/19　
　Heterogeneous nuclear ribonucleoprotein A2/B1 in association with hTERT is a potential biomarker for hepatocellular carcinoma.　Hideki Mizuno,Masao Honda,Takayoshi Shirasaki,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Shuichi Kaneko　Liver international : official journal of the International Association for the Study of the Liver　32　7　1146　2012/08
　The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma.　Zeng SS,Yamashita T,Kondo M,Nio K,Hayashi T,Hara Y,Nomura Y,Yoshida M,Hayashi T,Oishi N,Ikeda H,Honda M,Kaneko S　Journal of hepatology　60　1　127　2014/01
　Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: Possible link to serum anti-endothelial cell antibodies　Sato, Yasunori,Ren, Xiangshan,Harada, Kenichi,Sasaki, Motoko,Morikawa, Hiroyasu,Shiomi, Susumu,Honda, Masao,Kaneko, Shuichi,Nakanuma, Yasuni　Clinical and Experimental Immunology　167　3　532　2012/03/01　
　Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+ T-cell suppression.　Mami Higashimoto,Yoshio Sakai,Masayuki Takamura,Soichiro Usui,Alessandro Nasti,Keiko Yoshida,Akihiro Seki,Takuya Komura,Masao Honda,Takashi Wada,Kengo Furuichi,Takahiro Ochiya,Shuichi Kaneko　European journal of immunology　43　11　2956　2013/11
　Identification of blood biomarkers of aging by transcript profiling of whole blood.　Nakamura S,Kawai K,Takeshita Y,Honda M,Takamura T,Kaneko S,Matoba R,Matsubara K　Biochemical and biophysical research communications　418　2　313　2012/02
　Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.　Nishida N,Sawai H,Matsuura K,Sugiyama M,Ahn SH,Park JY,Hige S,Kang JH,Suzuki K,Kurosaki M,Asahina Y,Mochida S,Watanabe M,Tanaka E,Honda M,Kaneko S,Orito E,Itoh Y,Mita E,Tamori A,Murawaki Y,Hiasa Y,Sakaida I,Korenaga M,Hino K,Ide T,Kawashima M,Mawatari Y,Sageshima M,Ogasawara Y,Koike A,Izumi N,Han KH,Tanaka Y,Tokunaga K,Mizokami M　PloS one　7　6　e39175　2012
　Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients　Hiroko Shindo,Shinya Maekawa,Kazuki Komase,Ryota Sueki,Mika Miura,Makoto Kadokura,Kuniaki Shindo,Fumitake Amemiya,Takatoshi Kitamura,Yasuhiro Nakayama,Taisuke Inoue,Minoru Sakamoto,Shun-Ichi Okada,Yasuhiro Asahina,Namiki Izumi,Masao Honda,Shuichi Kaneko,Nobuyuki Enomoto　Hepatology International　6　2　482　2012/04
　Acyclic Retinoid Targets Platelet-Derived Growth Factor Signaling in the Prevention of Hepatic Fibrosis and Hepatocellular Carcinoma Development　Hikari Okada,Masao Honda,Jean S. Campbell,Yoshio Sakai,Taro Yamashita,Yuuki Takebuchi,Kazuhiro Hada,Takayoshi Shirasaki,Riuta Takabatake,Mikiko Nakamura,Hajime Sunagozaka,Takuji Tanaka,Nelson Fausto,Shuichi Kaneko　CANCER RESEARCH　72　17　4459　2012/09
　Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes　Yumie Takeshita,Toshinari Takamura,Yuki Kita,Hitoshi Ando,Teruyuki Ueda,Kenichiro Kato,Hirofumi Misu,Hajime Sunagozaka,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　METABOLISM-CLINICAL AND EXPERIMENTAL　61　10　1388　2012/10
　The biliary drainage for patients with obstructive jaundice due to hepatocellular carcinoma　NOMURA Yoshimoto,KAGAYA Takashi,UEDA Teruyuki,SUNAGOZAKA Hajime,TAKATORI Hajime,ARAI Kuniaki,KAKINOKI Kaheita,KAWAGUCHI Kazunori,KITAMURA Kazuya,YAMASHITA Taro,SAKAI Yoshio,YAMASHITA Tetsuya,MIZUKOSHI Eishiro,SAKAI Akito,HONDA Masao,KANEKO Shuichi　Kanzo　53　11　734　2012/11/25
　Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling.　Ueda T,Honda M,Horimoto K,Aburatani S,Saito S,Yamashita T,Sakai Y,Nakamura M,Takatori H,Sunagozaka H,Kaneko S　Genomics　101　4　238　2013/04
　Prognosis of autoimmune hepatitis showing acute presentation　Kazuhide Yamamoto,Yasuhiro Miyake,Hiromasa Ohira,Yoshiyuki Suzuki,Mikio Zeniya,Morikazu Onji,Hirohito Tsubouchi,Kaname Yoshizawa,Toshio Morizane,Toshifumi Hibi,Yutaka Aoyagi,Yasuni Nakanuma,Junko Hirohara,Hajime Takikawa,Hiromi Ishibashi,Shinji Shimoda,Shotaro Sakisaka,Makoto Nakamuta,Yasushi Matsuzaki,Toshiji Saibara,Yoshiyuki Ueno,Hiroshi Miyakawa,Norihiro Kokudo,Hiroto Egawa,Yoshihiko Maehara,Satoshi Mochida,Isao Sakaida,Tomoo Fujisawa,Kazuyuki Suzuki,Kazuaki Inoue,Takafumi Ichida,Osamu Yokosuka,Hiroshi Fukui,Hisataka Moriwaki,Mitsuru Mori,Toshiyuki Mori,Masato Nagino,Naohiro Sata,Susumu Tazuma,Takahiro Yasaka,Toshio Tsuyuguchi,Junichi Shoda,Masao Honda,Hiroki Yamaue,Michiaki Unno,Norio Hayashi　Hepatology Research　43　6　630　2013/06
　Erratum to Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling [Genomics 101, 4 (2013) 238-248]　Teruyuki Ueda,Masao Honda,Katsuhisa Horimoto,Sachiyo Aburatani,Shigeru Saito,Taro Yamashita,Yoshio Sakai,Mikiko Nakamura,Hajime Takatori,Hajime Sunagozaka,Shuichi Kaneko　Genomics　101　6　376　2013/06
　ER stress induced impaired TLR signaling and macrophage differentiation of human monocytes.　Takuya Komura,Yoshio Sakai,Masao Honda,Toshinari Takamura,Takashi Wada,Shuichi Kaneko　Cellular immunology　282　1　44　2013/03
　Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma　K Miyahara,K Nouso,Y Morimoto,Y Takeuchi,H Hagihara,K Kuwaki,H Onishi,F Ikeda,Y Miyake,S Nakamura,H Shiraha,A Takaki,M Honda,S Kaneko,T Sato,S Sato,S Obi,S Iwadou,Y Kobayashi,K Takaguchi,K Kariyama,Y Takuma,H Takabatake,K Yamamoto　British Journal of Cancer　109　8　2072　2013/10　
　Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma.　Yamashita T,Kitao A,Matsui O,Hayashi T,Nio K,Kondo M,Ohno N,Miyati T,Okada H,Yamashita T,Mizukoshi E,Honda M,Nakanuma Y,Takamura H,Ohta T,Nakamoto Y,Yamamoto M,Takayama T,Arii S,Wang X,Kaneko S　Hepatology (Baltimore, Md.)　60　5　1674　2014/11　
　Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis　Kazutoshi Yamada,Eishiro Mizukoshi,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Yumie Takeshita,Hirofumi Misu,Toshinari Takamura,Seiko Kitamura,Yoh Zen,Yasuni Nakanuma,Masao Honda,Shuichi Kaneko　LIVER INTERNATIONAL　35　2　582　2015/02
　[Diagnostic benefits of adrenocortical scintigraphy in hepatic adrenal rest tumor].　Ishida K,Horii R,Yamashita T,Arai K,Yamashita T,Kagaya T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　111　10　2004　2014/10
　Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice　Hikari Okada,Masao Honda,Jean S. Campbell,Kai Takegoshi,Yoshio Sakai,Taro Yamashita,Takayoshi Shirasaki,Riuta Takabatake,Mikiko Nakamura,Takuji Tanaka,Shuichi Kaneko　CANCER SCIENCE　106　9　1143　2015/09
　The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial　Yumie Takeshita,Toshinari Takamura,Masao Honda,Yuki Kita,Yoh Zen,Ken-ichiro Kato,Hirofumi Misu,Tsuguhito Ota,Mikiko Nakamura,Kazutoshi Yamada,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Shuichi Kaneko　DIABETOLOGIA　57　5　878　2014/05
　Inflammatory features of pancreatic cancer highlighted by monocytes/macrophages and CD4+ T cells with clinical impact.　Komura T,Sakai Y,Harada K,Kawaguchi K,Takabatake H,Kitagawa H,Wada T,Honda M,Ohta T,Nakanuma Y,Kaneko S　Cancer science　106　6　672　2015/06　
　Dynamics of an HBV Model with Drug Resistance Under Intermittent Antiviral Therapy.　Array,Gouhei Tanaka,Kazuyuki Aihara,Masao Honda,Shuichi Kaneko,Luonan Chen　I. J. Bifurcation and Chaos　25　7　2015　
　Hepatic Interferon-Stimulated Genes Are Differentially Regulated in the Liver of Chronic Hepatitis C Patients With Different Interleukin-28B Genotypes　Masao Honda,Takayoshi Shirasaki,Tetsuro Shimakami,Akito Sakai,Rika Horii,Kuniaki Arai,Tatsuya Yamashita,Yoshio Sakai,Taro Yamashita,Hikari Okada,Kazuhisa Murai,Mikiko Nakamura,Eishiro Mizukoshi,Shuichi Kaneko　HEPATOLOGY　59　3　828　2014/03
　Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma.　Nio K,Yamashita T,Okada H,Kondo M,Hayashi T,Hara Y,Nomura Y,Zeng SS,Yoshida M,Hayashi T,Sunagozaka H,Oishi N,Honda M,Kaneko S　Journal of hepatology　63　5　1164　2015/11
　Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C.　Etsuko Iio,Kentaro Matsuura,Nao Nishida,Shinya Maekawa,Nobuyuki Enomoto,Mina Nakagawa,Naoya Sakamoto,Hiroshi Yatsuhashi,Masayuki Kurosaki,Namiki Izumi,Yoichi Hiasa,Naohiko Masaki,Tatsuya Ide,Keisuke Hino,Akihiro Tamori,Masao Honda,Shuichi Kaneko,Satoshi Mochida,Hideyuki Nomura,Shuhei Nishiguchi,Chiaki Okuse,Yoshito Itoh,Hitoshi Yoshiji,Isao Sakaida,Kazuhide Yamamoto,Hisayoshi Watanabe,Shuhei Hige,Akihiro Matsumoto,Eiji Tanaka,Katsushi Tokunaga,Yasuhito Tanaka　Hum Genet　134　3　279　2015/03　
　TSU-68 ameliorates hepatocellular carcinoma growth by inhibiting microenvironmental platelet-derived growth factor signaling.　Hara Y,Yamashita T,Oishi N,Nio K,Hayashi T,Nomura Y,Yoshida M,Hayashi T,Hashiba T,Asahina Y,Kondo M,Okada H,Sunagozaka H,Honda M,Kaneko S　Anticancer research　35　3　1423　2015/03
　[A case of Wilson's disease in an elderly patient initially diagnosed with NASH].　Seishima J,Sakai Y,Kitahara N,Kitamura K,Arai K,Kagaya T,Yamashita T,Mizukoshi E,Honda M,Kaneko S　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　112　2　317　2015/02
　Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway　Takayoshi Shirasaki,Masao Honda,Tetsuro Shimakami,Kazuhisa Murai,Takayuki Shiomoto,Hikari Okada,Riuta Takabatake,Akihiro Tokumaru,Yoshio Sakai,Taro Yamashita,Stanley M. Lemon,Seishi Murakami,Shuichi Kaneko　Hepatology　60　5　1519　2014/11/01
　前臨床非アルコール性肝炎肝硬変マウスモデルに対する脂肪組織由来間質細胞投与による肝修復再生治療効果の検討　酒井佳夫,関晃裕,東元真実,吉田佳子,ナスティアレッサンドロ,小村卓也,本多政夫,金子周一,号:Supplement,ページ　Acta Hepatologica Japonica　2014/04　
　Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs.　Sara R Selitsky,Timothy A Dinh,Cynthia L Toth,C Lisa Kurtz,Masao Honda,Benjamin R Struck,Shuichi Kaneko,Kasey C Vickers,Stanley M Lemon,Praveen Sethupathy　mBio　6　6　e01500-15　2015/12/08
　Autoantibody status and histological variables influence biochemical response to treatment and long-term outcomes in Japanese patients with primary biliary cirrhosis.　Nakamura M,Kondo H,Tanaka A,Komori A,Ito M,Yamamoto K,Ohira H,Zeniya M,Hashimoto E,Honda M,Kaneko S,Ueno Y,Kikuchi K,Shimoda S,Harada K,Arai K,Miyake Y,Abe M,Taniai M,Saibara T,Sakisaka S,Takikawa H,Onji M,Tsubouchi H,Nakanuma Y,Ishibashi H　Hepatology research : the official journal of the Japan Society of Hepatology　45　8　846　2015/08
　Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C.　Etsuko Iio,Kentaro Matsuura,Nao Nishida,Shinya Maekawa,Nobuyuki Enomoto,Mina Nakagawa,Naoya Sakamoto,Hiroshi Yatsuhashi,Masayuki Kurosaki,Namiki Izumi,Yoichi Hiasa,Naohiko Masaki,Tatsuya Ide,Keisuke Hino,Akihiro Tamori,Masao Honda,Shuichi Kaneko,Satoshi Mochida,Hideyuki Nomura,Shuhei Nishiguchi,Chiaki Okuse,Yoshito Itoh,Hitoshi Yoshiji,Isao Sakaida,Kazuhide Yamamoto,Hisayoshi Watanabe,Shuhei Hige,Akihiro Matsumoto,Eiji Tanaka,Katsushi Tokunaga,Yasuhito Tanaka　Human genetics　134　3　279　2015/03
　[A case of chronic hepatitis B with liver failure due to untreated Basedow disease].　Shimizu Y,Kitahara M,Yamashita T,Arai K,Yamashita T,Kagaya T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　112　1　94　2015/01
　P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.　Terashima T,Mizukoshi E,Arai K,Yamashita T,Yoshida M,Ota H,Onishi I,Kayahara M,Ohtsubo K,Kagaya T,Honda M,Kaneko S　Cancer immunology, immunotherapy : CII　63　5　479　2014/05　
　Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.　Selitsky SR,Baran-Gale J,Honda M,Yamane D,Masaki T,Fannin EE,Guerra B,Shirasaki T,Shimakami T,Kaneko S,Lanford RE,Lemon SM,Sethupathy P　Scientific reports　5　7675　2015/01
　The Acyclic Retinoid Peretinoin Inhibits Hepatitis C Virus Replication and Infectious Virus Release in Vitro　Tetsuro Shimakami,Masao Honda,Takayoshi Shirasaki,Riuta Takabatake,Fanwei Liu,Kazuhisa Murai,Takayuki Shiomoto,Masaya Funaki,Daisuke Yamane,Seishi Murakami,Stanley M. Lemon,Shuichi Kaneko　SCIENTIFIC REPORTS　4　4688　2014/04
　Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy.　Terashima T,Yamashita T,Iida N,Yamashita T,Nakagawa H,Arai K,Kitamura K,Kagaya T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　Hepatology research : the official journal of the Japan Society of Hepatology　45　9　949　2015/09
　Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese individuals.　Nishida N,Ohashi J,Sugiyama M,Tsuchiura T,Yamamoto K,Hino K,Honda M,Kaneko S,Yatsuhashi H,Koike K,Yokosuka O,Tanaka E,Taketomi A,Kurosaki M,Izumi N,Sakamoto N,Eguchi Y,Sasazuki T,Tokunaga K,Mizokami M　Tissue antigens　86　6　406　2015/12
　Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis　Kazutoshi Yamada,Eishiro Mizukoshi,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Yumie Takeshita,Hirofumi Misu,Toshinari Takamura,Seiko Kitamura,Yoh Zen,Yasuni Nakanuma,Masao Honda,Shuichi Kaneko　LIVER INTERNATIONAL　35　6　1773　2015/06
　Feasibility and efficacy of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma after sorafenib.　Terashima T,Yamashita T,Arai K,Sunagozaka H,Kitahara M,Nakagawa H,Kagaya T,Mizukoshi E,Honda M,Kaneko S　Hepatology research : the official journal of the Japan Society of Hepatology　44　12　1179　2014/11　
　A hybrid model for hepatitis B virus　Ben-Gong Zhang,Gouhei Tanaka,Kazuyuki Aihara,Masao Honda,Shuichi Kaneko,Luonan Chen　IFAC-PapersOnLine　28　18　37　2015/11/01
　New Susceptibility and Resistance HLA-DP Alleles to HBV-Related Diseases Identified by a Trans-Ethnic Association Study in Asia　Nao Nishida,Hiromi Sawai,Koichi Kashiwase,Mutsuhiko Minami,Masaya Sugiyama,Wai-Kay Seto,Man-Fung Yuen,Nawarat Posuwan,Yong Poovorawan,Sang Hoon Ahn,Kwang-Hyub Han,Kentaro Matsuura,Yasuhito Tanaka,Masayuki Kurosaki,Yasuhiro Asahina,Namiki Izumi,Jong-Hon Kang,Shuhei Hige,Tatsuya Ide,Kazuhide Yamamoto,Isao Sakaida,Yoshikazu Murawaki,Yoshito Itoh,Akihiro Tamori,Etsuro Orito,Yoichi Hiasa,Masao Honda,Shuichi Kaneko,Eiji Mita,Kazuyuki Suzuki,Keisuke Hino,Eiji Tanaka,Satoshi Mochida,Masaaki Watanabe,Yuichiro Eguchi,Naohiko Masaki,Kazumoto Murata,Masaaki Korenaga,Yoriko Mawatari,Jun Ohashi,Minae Kawashima,Katsushi Tokunaga,Masashi Mizokami　PLOS ONE　9　2　e86449　2014/02
　Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet.　Hikari Okada,Riuta Takabatake,Masao Honda,Kai Takegoshi,Taro Yamashita,Mikiko Nakamura,Takayoshi Shirasaki,Yoshio Sakai,Tetsuro Shimakami,Naoto Nagata,Toshinari Takamura,Takuji Tanaka,Shuichi Kaneko　Oncotarget　8　25　39978　2017/06/20
　Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population　Kawashima, Minae,Hitomi, Yuki,Aiba, Yoshihiro,Nishida, Nao,Kojima, Kaname,Kawai, Yosuke,Nakamura, Hitomi,Tanaka, Atsushi,Zeniya, Mikio,Hashimoto, Etsuko,Ohira, Hiromasa,Yamamoto, Kazuhide,Abe, Masanori,Nakao, Kazuhiko,Yamagiwa, Satoshi,Kaneko, Shuichi,Honda, Masao,Umemura, Takeji,Ichida, Takafumi,Seike, Masataka,Sakisaka, Shotaro,Harada, Masaru,Yokosuka, Osamu,Ueno, Yoshiyuki,Senju, Michio,Kanda, Tatsuo,Shibata, Hidetaka,Himoto, Takashi,Murata, Kazumoto,Miyake, Yasuhiro,Ebinuma, Hirotoshi,Taniai, Makiko,Joshita, Satoru,Nikami, Toshiki,Ota, Hajime,Kouno, Hiroshi,Kouno, Hirotaka,Nakamuta, Makoto,Fukushima, Nobuyoshi,Kohjima, Motoyuki,Komatsu, Tatsuji,Komeda, Toshiki,Ohara, Yukio,Muro, Toyokichi,Yamashita, Tsutomu,Yoshizawa, Kaname,Nakamura, Yoko,Shimada, Masaaki,Hirashima, Noboru,Sugi, Kazuhiro,Ario, Keisuke,Takesaki, Eiichi,Naganuma, Atsushi,Mano, Hiroshi,Yamashita, Haruhiro,Matsushita, Kouki,Yamauchi, Kazuhiko,Makita, Fujio,Nishimura, Hideo,Furuta, Kiyoshi,Takahashi, Naohiro,Kikuchi, Masahiro,Masaki, Naohiko,Tanaka, Tomohiro,Tamura, Sumito,Mori, Akira,Yagi, Shintaro,Shirabe, Ken,Komori, Atsumasa,Migita, Kiyoshi,Ito, Masahiro,Nagaoka, Shinya,Abiru, Seigo,Yatsuhashi, Hiroshi,Yasunami, Michio,Shimoda, Shinji,Harada, Kenichi,Egawa, Hiroto,Maehara, Yoshihiko,Uemoto, Shinji,Kokudo, Norihiro,Takikawa, Hajime,Ishibashi, Hiromi,Chayama, Kazuaki,Mizokami, Masashi,Nagasaki, Masao,Tokunaga, Katsushi,Nakamura, Minoru　HUMAN MOLECULAR GENETICS　26　3　650　2017/02/01
　Response to chemotherapy improves hepatic reserve for patients with hepatocellular carcinoma and Child-Pugh B cirrhosis.　Takeshi Terashima,Tatsuya Yamashita,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Cancer science　107　9　1263　2016/09
　Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis　Nao Nishida,Jun Ohashi,Seik-Soon Khor,Masaya Sugiyama,Takayo Tsuchiura,Hiromi Sawai,Keisuke Hino,Masao Honda,Shuichi Kaneko,Hiroshi Yatsuhashi,Osamu Yokosuka,Kazuhiko Koike,Masayuki Kurosaki,Namiki Izumi,Masaaki Korenaga,Jong-Hon Kang,Eiji Tanaka,Akinobu Taketomi,Yuichiro Eguchi,Naoya Sakamoto,Kazuhide Yamamoto,Akihiro Tamori,Isao Sakaida,Shuhei Hige,Yoshito Itoh,Satoshi Mochida,Eiji Mita,Yasuhiro Takikawa,Tatsuya Ide,Yoichi Hiasa,Hiroto Kojima,Ken Yamamoto,Minoru Nakamura,Hiroh Saji,Takehiko Sasazuki,Tatsuya Kanto,Katsushi Tokunaga,Masashi Mizokami　SCIENTIFIC REPORTS　6　24767　2016/04
　De Novo Emergence of Mesenchymal Stem-Like CD105⁺ Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma.　Nomura Y,Yamashita T,Oishi N,Nio K,Hayashi T,Yoshida M,Hayashi T,Hashiba T,Asahina Y,Okada H,Sunagozaka H,Takatori H,Honda M,Kaneko S　Translational oncology　10　2　184　2017/04
　Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems.　Liu F,Shimakami T,Murai K,Shirasaki T,Funaki M,Honda M,Murakami S,Yi M,Tang H,Kaneko S　Scientific reports　6　30939　2016/08
　Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B　Xuyang Wang,Naoki Oishi,Tetsuro Shimakami,Taro Yamashita,Masao Honda,Seishi Murakami,Shuichi Kaneko　WORLD JOURNAL OF GASTROENTEROLOGY　23　18　3252　2017/05
　Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma　Takeshi Terashima,Tatsuya Yamashita,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　LIVER CANCER　6　3　236　2017
　Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib.　Terashima T,Yamashita T,Takata N,Nakagawa H,Toyama T,Arai K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　Hepatology research : the official journal of the Japan Society of Hepatology　46　7　650　2016/06　
　Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma.　Komura T,Takabatake H,Harada K,Yamato M,Miyazawa M,Yoshida K,Honda M,Wada T,Kitagawa H,Ohta T,Kaneko S,Sakai Y　Cancer science　108　11　2122　2017/11
　Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model　Kai Takegoshi,Masao Honda,Hikari Okada,Riuta Takabatake,Naoto Matsuzawa-Nagata,Jean S. Campbell,Masashi Nishikawa,Tetsuro Shimakami,Takayoshi Shirasaki,Yoshio Sakai,Taro Yamashita,Toshinari Takamura,Takuji Tanaka,Shuichi Kaneko　ONCOTARGET　8　11　18191　2017/03
　Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma.　Honda M,Shirasaki T,Terashima T,Kawaguchi K,Nakamura M,Oishi N,Wang X,Shimakami T,Okada H,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S　The Journal of infectious diseases　213　7　1096　2016/04
　Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection　Kentaro Matsuura,Hiromi Sawai,Kazuho Ikeo,Shintaro Ogawa,Etsuko Iio,Masanori Isogawa,Noritomo Shimada,Atsumasa Komori,Hidenori Toyoda,Takashi Kumada,Tadashi Namisaki,Hitoshi Yoshiji,Naoya Sakamoto,Mina Nakagawa,Yasuhiro Asahina,Masayuki Kurosaki,Namiki Izumi,Nobuyuki Enomoto,Atsunori Kusakabe,Eiji Kajiwara,Yoshito Itoh,Tatsuya Ide,Akihiro Tamori,Misako Matsubara,Norifumi Kawada,Ken Shirabe,Eiichi Tomita,Masao Honda,Shuichi Kaneko,Sohji Nishina,Atsushi Suetsugu,Yoichi Hiasa,Hisayoshi Watanabe,Takuya Genda,Isao Sakaida,Shuhei Nishiguchi,Koichi Takaguchi,Eiji Tanaka,Junichi Sugihara,Mitsuo Shimada,Yasuteru Kondo,Yosuke Kawai,Kaname Kojima,Masao Nagasaki,Katsushi Tokunaga,Yasuhito Tanaka　Gastroenterology　152　6　1383　2017/05
　Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma.　Terashima T,Yamashita T,Horii R,Arai K,Kawaguchi K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　BMC cancer　16　338　2016/05
　Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication　Hiroe Sejima,Shinya Satoh,Hiromichi Dansako,Masao Honda,Shuichi Kaneko,Masanori Ikeda,Nobuyuki Kato　ACTA MEDICA OKAYAMA　70　2　75　2016/04
　Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection.　Murata K,Asano M,Matsumoto A,Sugiyama M,Nishida N,Tanaka E,Inoue T,Sakamoto M,Enomoto N,Shirasaki T,Honda M,Kaneko S,Gatanaga H,Oka S,Kawamura YI,Dohi T,Shuno Y,Yano H,Mizokami M　Gut　67　2　362　2016/10　
　Direct-acting antiviral agents improved nephrotic syndrome associated with refractory pleural effusion and ascites caused by hepatitis C virus-related nephropathy: a case report.　Yamato M,Arai K,Takatori H,Shimakami T,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Honda M,Kaneko S　Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology　114　6　1031　2017
　Altered gene expression in T-cell receptor signalling in peripheral blood leucocytes in acute coronary syndrome predicts secondary coronary events.　Takashima S,Usui S,Kurokawa K,Kitano T,Kato T,Murai H,Furusho H,Oda H,Maruyama M,Nagata Y,Usuda K,Kubota K,Takeshita Y,Sakai Y,Honda M,Kaneko S,Takamura M　Open heart　3　1　e000400　2016
　Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer.　Kawaguchi K,Honda M,Yamashita T,Okada H,Shirasaki T,Nishikawa M,Nio K,Arai K,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S　The American journal of pathology　186　8　2055　2016/08　
　Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3 ' variants　Daisuke Yamane,Sara R. Selitsky,Tetsuro Shimakami,You Li,Mi Zhou,Masao Honda,Praveen Sethupathy,Stanley M. Lemon　NUCLEIC ACIDS RESEARCH　45　8　4743　2017/05
　Phase I clinical study of liver regenerative therapy for cirrhosis by intrahepatic arterial infusion of freshly isolated autologous adipose tissue-derived stromal/stem (regenerative) cell　Yoshio Sakai,Masayuki Takamura,Akihiro Seki,Hajime Sunagozaka,Takeshi Terashima,Takuya Komura,Masatoshi Yamato,Masaki Miyazawa,Kazunori Kawaguchi,Alessandro Nasti,Hatsune Mochida,Soichiro Usui,Nobuhisa Otani,Takahiro Ochiya,Takashi Wada,Masao Honda,Shuichi Kaneko　REGENERATIVE THERAPY　6　52　2017/06
　Sorafenib suppresses extrahepatic metastasis de novo in hepatocellular carcinoma through inhibition of mesenchymal cancer stem cells characterized by the expression of CD90.　Yoshida M,Yamashita T,Okada H,Oishi N,Nio K,Hayashi T,Nomura Y,Hayashi T,Asahina Y,Ohwada M,Sunagozaka H,Takatori H,Colombo F,Porretti L,Honda M,Kaneko S　Scientific reports　7　1　11292　2017/09
　Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma.　Hayashi T,Yamashita T,Okada H,Nio K,Hara Y,Nomura Y,Hayashi T,Asahina Y,Yoshida M,Oishi N,Sunagozaka H,Takatori H,Honda M,Kaneko S　Cancer cell international　17　94　2017
　The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis　Hirayuki Enomoto,Lihua Tao,Ryoji Eguchi,Ayuko Sato,Masao Honda,Shuichi Kaneko,Yoshinori Iwata,Hiroki Nishikawa,Hiroyasu Imanishi,Hiroko Iijima,Tohru Tsujimura,Shuhei Nishiguchi　SCIENTIFIC REPORTS　7　2017/09
　Prognosis of type 1 autoimmune pancreatitis after corticosteroid therapy-induced remission in terms of relapse and diabetes mellitus　Masaki Miyazawa,Hajime Takatori,Tetsuro Shimakami,Kazunori Kawaguchi,Kazuya Kitamura,Kuniaki Arai,Koichiro Matsuda,Taku Sanada,Takeshi Urabe,Katsuhisa Inamura,Takashi Kagaya,Hideki Mizuno,Uichiro Fuchizaki,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　PLOS ONE　12　11　e0188549　2017/11
　The CD45(+) fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells　Alessandro Nasti,Yoshio Sakai,Akihiro Seki,Geraldine Belen Buffa,Takuya Komura,Hatsune Mochida,Masatoshi Yamato,Keiko Yoshida,Tuyen T. B. Ho,Masayuki Takamura,Soichiro Usui,Takashi Wada,Masao Honda,Shuichi Kaneko　EUROPEAN JOURNAL OF IMMUNOLOGY　47　12　2163　2017/12
　Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: Prospects for regorafenib therapy.　Terashima T,Yamashita T,Sunagozaka H,Arai K,Kawaguchi K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S　Hepatology research : the official journal of the Japan Society of Hepatology　48　12　956　2018/05
　Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.　Takeshi Terashima,Tatsuya Yamashita,Tadashi Toyama,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Liver cancer　8　2　130　2019/03
　Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models.　Sakai Y,Miyazawa M,Komura T,Yamada T,Nasti A,Yoshida K,Takabatake H,Yamato M,Yamashita T,Yamashita T,Mizukoshi E,Okuzono M,Ho TTB,Kawaguchi K,Wada T,Honda M,Kaneko S　Cancer Sci　110　3　903　2019/03
　Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.　Kazuhisa Murai,Masao Honda,Takayoshi Shirasaki,Tetsuro Shimakami,Hitoshi Omura,Hirofumi Misu,Yuki Kita,Yumie Takeshita,Kiyo-Aki Ishii,Toshinari Takamura,Takeshi Urabe,Ryogo Shimizu,Hikari Okada,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko　Cell host & microbe　25　4　588　2019/04/10
　Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study.　Hayashi T,Yamashita T,Terashima T,Suda T,Okada H,Asahina Y,Hayashi T,Hara Y,Nio K,Sunagozaka H,Takatori H,Arai K,Sakai Y,Yamashita T,Mizukoshi E,Honda M,Kaneko S　BMC cancer　17　1　870　2017/12　
　Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis　Shinya Satoh,Daichi Onomura,Youki Ueda,Hiromichi Dansako,Masao Honda,Shuichi Kaneko,Nobuyuki Kato　Biochemical Journal　476　1　137　2019/01/15　
　ヒト肝がんにおけるシングルセル遺伝子発現解析(Single cell gene expression profiling in human hepatocellular carcinoma)　岩淵禎弘,川口和紀,本多政夫,山下太郎,酒井佳夫,水腰英四郎,金子周一,橋本真一　日本癌学会総会記事　77回　1392　2018/09
　Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B.　Kawaguchi K,Honda M,Ohta H,Terashima T,Shimakami T,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Komura T,Unoura M,Kaneko S　Journal of gastroenterology　53　6　740　2018/06
　Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation.　Haruo Fujinaga,Yoshio Sakai,Tatsuya Yamashita,Kuniaki Arai,Takeshi Terashima,Takuya Komura,Akihiro Seki,Kazunori Kawaguchi,Alessandro Nasti,Keiko Yoshida,Takashi Wada,Kazutaka Yamamoto,Kyo Kume,Takashi Hasegawa,Takushi Takata,Masao Honda,Shuichi Kaneko　International journal of radiation biology　95　5　571　2019/05
　Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells.　Sakai Y,Honda M,Matsui S,Komori O,Murayama T,Fujiwara T,Mizuno M,Imai Y,Yoshimura K,Nasti A,Wada T,Iida N,Kitahara M,Horii R,Toshikatsu T,Nishikawa M,Okafuji H,Mizukoshi E,Yamashita T,Yamashita T,Arai K,Kitamura K,Kawaguchi K,Takatori H,Shimakami T,Terashima T,Hayashi T,Nio K,Kaneko S,Hokuriku Liver,Study Group　Cancer science　110　4　1364　2019/04　
　Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.　Sawai H,Nishida N,Khor SS,Honda M,Sugiyama M,Baba N,Yamada K,Sawada N,Tsugane S,Koike K,Kondo Y,Yatsuhashi H,Nagaoka S,Taketomi A,Fukai M,Kurosaki M,Izumi N,Kang JH,Murata K,Hino K,Nishina S,Matsumoto A,Tanaka E,Sakamoto N,Ogawa K,Yamamoto K,Tamori A,Yokosuka O,Kanda T,Sakaida I,Itoh Y,Eguchi Y,Oeda S,Mochida S,Yuen MF,Seto WK,Poovorawan Y,Posuwan N,Mizokami M,Tokunaga K　Scientific reports　8　1　7958　2018/05
　The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.　Shirasaki T,Honda M,Yamashita T,Nio K,Shimakami T,Shimizu R,Nakasyo S,Murai K,Shirasaki N,Okada H,Sakai Y,Sato T,Suzuki T,Yoshioka K,Kaneko S　Scientific reports　8　1　13143　2018/09
　Three renal failure cases successfully treated with ombitasvir/paritaprevir/ritonavir for genotype 1b hepatitis C virus reinfection after liver transplantation.　Orita N,Shimakami T,Sunagozaka H,Horii R,Nio K,Terashima T,Iida N,Kitahara M,Takatori H,Kawaguchi K,Kitamura K,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Honda M,Kaneko S　Clinical journal of gastroenterology　12　1　63　2018/07
　Unexpected Replication Boost by Simeprevir for Simeprevir-Resistant Variants in Genotype 1a Hepatitis C Virus.　Murai K,Shimakami T,Welsch C,Shirasaki T,Liu F,Kitabayashi J,Tanaka S,Funaki M,Omura H,Nishikawa T,Sumiyadorj A,Honda M,Kaneko S　Antimicrobial agents and chemotherapy　62　7　2018/07
　Single cell gene expression profiling in human hepatocellular carcinoma　Iwabuchi, Sadahiro,Kawaguchi, Kazunori,Honda, Masao,Yamashita, Taro,Sakai, Yoshio,Mizukoshi, Eishiro,Kaneko, Shuichi,Hashimoto, Shinichi　CANCER SCIENCE　109　941　2018/12
　POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.　Hitomi Y,Ueno K,Kawai Y,Nishida N,Kojima K,Kawashima M,Aiba Y,Nakamura H,Kouno H,Kouno H,Ohta H,Sugi K,Nikami T,Yamashita T,Katsushima S,Komeda T,Ario K,Naganuma A,Shimada M,Hirashima N,Yoshizawa K,Makita F,Furuta K,Kikuchi M,Naeshiro N,Takahashi H,Mano Y,Yamashita H,Matsushita K,Tsunematsu S,Yabuuchi I,Nishimura H,Shimada Y,Yamauchi K,Komatsu T,Sugimoto R,Sakai H,Mita E,Koda M,Nakamura Y,Kamitsukasa H,Sato T,Nakamuta M,Masaki N,Takikawa H,Tanaka A,Ohira H,Zeniya M,Abe M,Kaneko S,Honda M,Arai K,Arinaga-Hino T,Hashimoto E,Taniai M,Umemura T,Joshita S,Nakao K,Ichikawa T,Shibata H,Takaki A,Yamagiwa S,Seike M,Sakisaka S,Takeyama Y,Harada M,Senju M,Yokosuka O,Kanda T,Ueno Y,Ebinuma H,Himoto T,Murata K,Shimoda S,Nagaoka S,Abiru S,Komori A,Migita K,Ito M,Yatsuhashi H,Maehara Y,Uemoto S,Kokudo N,Nagasaki M,Tokunaga K,Nakamura M　Scientific reports　9　1　102　2019/01　
　Immune responses against tumour-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients.　Kida A,Mizukoshi E,Tamai T,Terashima T,Kitahara M,Arai K,Yamashita T,Fushimi K,Honda M,Kaneko S　Liver international : official journal of the International Association for the Study of the Liver　38　11　2040　2018/05
　Establishment and Characterization of a New Cell Line Permissive for Hepatitis C Virus Infection.　Hitoshi Omura,Fanwei Liu,Tetsuro Shimakami,Kazuhisa Murai,Takayoshi Shirasaki,Juria Kitabayashi,Masaya Funaki,Tomoki Nishikawa,Ryotaro Nakai,Ariunaa Sumiyadorj,Takehiro Hayashi,Taro Yamashita,Masao Honda,Shuichi Kaneko　Scientific reports　9　1　7943　2019/05/28
　Characteristics of Immune Response to Tumor-Associated Antigens and Immune Cell Profile in Patients With Hepatocellular Carcinoma.　Yuki Inada,Eishiro Mizukoshi,Takuya Seike,Toshikatsu Tamai,Noriho Iida,Masaaki Kitahara,Tatsuya Yamashita,Kuniaki Arai,Takeshi Terashima,Kazumi Fushimi,Taro Yamashita,Masao Honda,Shuichi Kaneko　Hepatology (Baltimore, Md.)　69　2　653　2019/02
　Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation.　Wang Z,Kawaguchi K,Honda M,Hashimoto S,Shirasaki T,Okada H,Orita N,Shimakami T,Yamashita T,Sakai Y,Mizukoshi E,Murakami S,Kaneko S　Scientific reports　9　1　1621　2019/02
　Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease　Kazutoshi Yamada,Eishiro Mizukoshi,Takuya Seike,Rika Horii,Masaaki Kitahara,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko　PLoS ONE　13　1　e0191026　2018/01/01
　Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis.　Yamada K,Mizukoshi E,Seike T,Horii R,Terashima T,Iida N,Kitahara M,Sunagozaka H,Arai K,Yamashita T,Honda M,Takamura T,Harada K,Kaneko S　Journal of gastroenterology and hepatology　34　10　1829　2019/10
　Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data.　Kyoko Yoshida,Alice Desbiolles,Sarah F Feldman,Sang Hoon Ahn,Enagnon K Alidjinou,Masanori Atsukawa,Laurence Bocket,Maurizia R Brunetto,Maria Buti,Ivana Carey,Gian Paolo Caviglia,En-Qiang Chen,Markus Cornberg,Masaru Enomoto,Masao Honda,Christoph Höner Zu Siederdissen,Masatoshi Ishigami,Harry LA Janssen,Benjamin Maasoumy,Takeshi Matsui,Akihiro Matsumoto,Shuhei Nishiguchi,Mar Riveiro-Barciela,Akinobu Takaki,Pisit Tangkijvanich,Hidenori Toyoda,Margo Jh van Campenhout,Bo Wang,Lai Wei,Hwai-I Yang,Yoshihiko Yano,Hiroshi Yatsuhashi,Man-Fung Yuen,Eiji Tanaka,Maud Lemoine,Yasuhito Tanaka,Yusuke Shimakawa　Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association　19　1　46　2020/04/29
　IL-28B variant as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy.　Takeshi Terashima,Masao Honda,Tadashi Toyama,Tetsuro Shimakami,Ryogo Shimizu,Hajime Takatori,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Shuichi Kaneko　Journal of gastroenterology and hepatology　35　10　1813　2020/03/16
　Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.　Tomoki Nishikawa,Naoto Nagata,Tetsuro Shimakami,Takashi Shirakura,Chieko Matsui,Yinhua Ni,Fen Zhuge,Liang Xu,Guanliang Chen,Mayumi Nagashimada,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko,Tsuguhito Ota　Scientific reports　10　1　815　2020/01/21
　A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma.　Toshikatsu Tamai,Eishiro Mizukoshi,Masashi Kumagai,Takeshi Terashima,Noriho Iida,Masaaki Kitahara,Tetsuro Shimakami,Kazuya Kitamura,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Kazumi Fushimi,Shuichi Kaneko　Scientific reports　10　1　4021　2020/03/04
　Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.　Kanno M,Kawaguchi K,Honda M,Horii R,Takatori H,Shimakami T,Kitamura K,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S　Journal of gastroenterology　54　6　549　2019/06
　Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.　Masatoshi Yamato,Yoshio Sakai,Hatsune Mochida,Kazunori Kawaguchi,Masayuki Takamura,Soichiro Usui,Akihiro Seki,Eishiro Mizukoshi,Taro Yamashita,Tatsuya Yamashita,Kousuke Ishida,Alessandro Nasti,Ho Thuy Bich Tuyen,Takuya Komura,Keiko Yoshida,Takashi Wada,Masao Honda,Shuichi Kaneko　Journal of gastroenterology and hepatology　34　8　1432　2019/08
　Characteristics of Impaired Dendritic Cell Function in Patients With Hepatitis B Virus Infection.　Yonejima A,Mizukoshi E,Tamai T,Nakagawa H,Kitahara M,Yamashita T,Arai K,Terashima T,Iida N,Fushimi K,Okada H,Yamashita T,Sakai Y,Honda M,Kaneko S　Hepatology (Baltimore, Md.)　70　1　25　2019/07
　Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma.　Tomomi Hashiba,Taro Yamashita,Hikari Okada,Kouki Nio,Takehiro Hayashi,Yoshiro Asahina,Tomoyuki Hayashi,Takeshi Terashima,Noriho Iida,Hajime Takatori,Tetsuro Shimakami,Kazunori Kawaguchi,Kuniaki Arai,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Hiroyuki Takamura,Tetsuo Ohta,Masao Honda,Shuichi Kaneko　Cellular and molecular gastroenterology and hepatology　10　2　269　2020
　Direct-Acting Antiviral Agents Reduce the Risk of Malignant Transformation of Hepatobiliary Phase-Hypointense Nodule without Arterial Phase Hyperenhancement to Hepatocellular Carcinoma on Gd-EOB-DPTA-Enhanced Imaging in the Hepatitis C Virus-Infected Liver.　Yoshiaki Shimizu,Kuniaki Arai,Taro Yamashita,Tatsuya Yamashita,Tetsuro Shimakami,Kazunori Kawaguchi,Kazuya Kitamura,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Azusa Kitao,Kazuto Kozaka,Satoshi Kobayashi,Shuichi Kaneko　Liver cancer　9　3　261　2020/06
　ヒト非B非C肝癌におけるシングルセル遺伝子発現解析(Single-cell transcriptome analysis in human NBNC hepatocellular carcinoma)　岩淵禎弘,川口和紀,本多政夫,山下太郎,山下竜也,金子周一,橋本真一　日本癌学会総会記事　78回　P　2019/09
　ヒト非B非C肝癌におけるシングルセル遺伝子発現解析(Single-cell transcriptome analysis in human NBNC hepatocellular carcinoma)　岩淵禎弘,川口和紀,本多政夫,山下太郎,山下竜也,金子周一,橋本真一　日本癌学会総会記事　78回　P　2019/09
　MicroRNA-10a Impairs Liver Metabolism in Hepatitis C Virus-Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator-Like 1.　Rika Horii,Masao Honda,Takayoshi Shirasaki,Tetsuro Shimakami,Ryogo Shimizu,Souma Yamanaka,Kazuhisa Murai,Kazunori Kawaguchi,Kuniaki Arai,Tatsuya Yamashita,Yoshio Sakai,Taro Yamashita,Hikari Okada,Mikiko Nakamura,Eishiro Mizukoshi,Shuichi Kaneko　Hepatology communications　3　12　1687　2019/12
　Danaparoid sodium-based anticoagulation therapy for portal vein thrombosis in cirrhosis patients.　Takehiro Hayashi,Hajime Takatori,Rika Horii,Kouki Nio,Takeshi Terashima,Noriho Iida,Masaaki Kitahara,Tetsuro Shimakami,Kuniaki Arai,Kazuya Kitamura,Kazunori Kawaguchi,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Tadashi Toyama,Kenichiro Okumura,Kazuto Kozaka,Shuichi Kaneko　BMC gastroenterology　19　1　217　2019/12/16
　Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host.　Jun Seishima,Noriho Iida,Kazuya Kitamura,Masahiro Yutani,Ziyu Wang,Akihiro Seki,Taro Yamashita,Yoshio Sakai,Masao Honda,Tatsuya Yamashita,Takashi Kagaya,Yukihiro Shirota,Yukako Fujinaga,Eishiro Mizukoshi,Shuichi Kaneko　Genome biology　20　1　252　2019/11/25
　Management of biliary stricture in patients with IgG4-related sclerosing cholangitis.　Masaki Miyazawa,Hajime Takatori,Kazunori Kawaguchi,Kazuya Kitamura,Kuniaki Arai,Koichiro Matsuda,Takeshi Urabe,Katsuhisa Inamura,Takuya Komura,Hideki Mizuno,Uichiro Fuchizaki,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　PloS one　15　4　e0232089　2020
　Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial.　Yoshio Sakai,Shinya Fukunishi,Masayuki Takamura,Oto Inoue,Shinichiro Takashima,Soichiro Usui,Akihiro Seki,Alessandro Nasti,Tuyen Thuy Bich Ho,Kazunori Kawaguchi,Akira Asai,Yusuke Tsuchimoto,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Yasuhito Imai,Kenichi Yoshimura,Toshinori Murayama,Takashi Wada,Kenichi Harada,Kazuhide Higuchi,Shuichi Kaneko　JMIR research protocols　9　3　e17904　2020/03/31
　Comparative analysis of liver functional reserve during lenvatinib and sorafenib for advanced hepatocellular carcinoma.　Takeshi Terashima,Tatsuya Yamashita,Noboru Takata,Tadashi Toyama,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Hepatology research : the official journal of the Japan Society of Hepatology　50　7　871　2020/07
　Effects of adaptive immune cell therapy on the immune cell profile in patients with advanced gastric cancer.　Miyabi Miura,Eishiro Mizukoshi,Tomomi Hashiba,Masaaki Kitahara,Tomoharu Miyashita,Takafumi Mochizuki,Shigenori Goto,Takashi Kamigaki,Rishu Takimoto,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko　Cancer medicine　9　14　4907　2020/07
　DOCK11 and DENND2A play pivotal roles in the maintenance of hepatitis B virus in host cells.　Shinichi Hashimoto,Takayoshi Shirasaki,Taro Yamashita,Sadahiro Iwabuchi,Yutaka Suzuki,Yuzuru Takamura,Yoshiaki Ukita,Shungo Deshimaru,Toshitugu Okayama,Kazuho Ikeo,Kazuyuki Kuroki,Kazunori Kawaguchi,Eishiro Mizukoshi,Kouji Matsushima,Masao Honda,Shuichi Kaneko　PloS one　16　2　e0246313　2021
　シングルセル解析による肝腺腫のバイオマーカーの探索　岩淵禎弘,川口和紀,本多政夫,山下太郎,山下竜也,金子周一,橋本真一　日本癌学会総会記事　79回　PJ14　2020/10
　Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis.　Tuyen Thuy Bich Ho,Alessandro Nasti,Akihiro Seki,Takuya Komura,Hiiro Inui,Takashi Kozaka,Yoji Kitamura,Kazuhiro Shiba,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Kazunori Kawaguchi,Takashi Wada,Masao Honda,Shuichi Kaneko,Yoshio Sakai　Journal for immunotherapy of cancer　8　2　2020/11
　Fatty acid-driven modifications in T-cell profiles in non-alcoholic fatty liver disease patients.　Takuya Seike,Eishiro Mizukoshi,Kazutoshi Yamada,Hikari Okada,Masaaki Kitahara,Tatsuya Yamashita,Kuniaki Arai,Takeshi Terashima,Noriho Iida,Kazumi Fushimi,Taro Yamashita,Yoshio Sakai,Masao Honda,Kenichi Harada,Shuichi Kaneko　Journal of gastroenterology　55　7　701　2020/07
　Tumor lysis syndrome in a patient with metastatic melanoma treated with nivolumab.　Saiho Sugimoto,Takeshi Terashima,Tatsuya Yamashita,Noriho Iida,Masaaki Kitahara,Yuji Hodo,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Yukihiro Shirota,Katsuaki Sato,Eishiro Mizukoshi,Masao Honda,Kenichi Harada,Shuichi Kaneko　Clinical journal of gastroenterology　13　5　935　2020/06/27
　Investigation of Thrombosis Volume, Anticoagulants, and Recurrence Factors in Portal Vein Thrombosis with Cirrhosis　Tsuyoshi Suda,Hajime Takatori,Takehiro Hayashi,Rika Horii,Kouki Nio,Takeshi Terashima,Noriho Iida,Masaaki Kitahara,Tetsuro Shimakami,Kuniaki Arai,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Kenichiro Okumura,Kazuto Kozaka,Shuichi Kaneko　Life　10　9　177　2020/09/04　
　Dysbiotic gut microbiota in pancreatic cancer patients form correlation networks with the oral microbiota and prognostic factors.　Hiroki Matsukawa,Noriho Iida,Kazuya Kitamura,Takeshi Terashima,Jun Seishima,Isamu Makino,Takayuki Kannon,Kazuyoshi Hosomichi,Taro Yamashita,Yoshio Sakai,Masao Honda,Tatsuya Yamashita,Eishiro Mizukoshi,Shuichi Kaneko　American journal of cancer research　11　6　3163　2021
　シングルセル解析による肝腺腫のバイオマーカーの探索　岩淵禎弘,川口和紀,本多政夫,山下太郎,山下竜也,金子周一,橋本真一　日本癌学会総会記事　79回　PJ14　2020/10
　Upregulation of the Long Non-Coding RNA HULC by Hepatitis C Virus and its Regulation of Viral Replication.　Juria Kitabayashi,Takayoshi Shirasaki,Tetsuro Shimakami,Tomoaki Nishiyama,Christoph Welsch,Masaya Funaki,Kazuhisa Murai,Ariunaa Sumiyadorj,Hajime Takatori,Kazuya Kitamura,Kazunori Kawaguchi,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　The Journal of infectious diseases　226　3　407　2020/06/09
　Safety and Long-Term Outcome of Intratumoral Injection of OK432-Stimulated Dendritic Cells for Hepatocellular Carcinomas After Radiofrequency Ablation.　Masaaki Kitahara,Eishiro Mizukoshi,Takeshi Terashima,Hidetoshi Nakagawa,Rika Horii,Noriho Iida,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Yasunari Nakamoto,Shuichi Kaneko　Translational oncology　13　7　100777　2020/07
　Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice.　Takayoshi Shirasaki,Kazuhisa Murai,Masao Honda,Hikari Okada,Yuika Innami,Atsumu Yamada,Tetsuro Shimakami,Kazunori Kawaguchi,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko　Scientific reports　11　1　13021　2021/06/22
　Safety and efficacy of sorafenib followed by regorafenib or lenvatinib in patients with hepatocellular carcinoma.　Takeshi Terashima,Tatsuya Yamashita,Noboru Takata,Yasuhito Takeda,Hidenori Kido,Noriho Iida,Masaaki Kitahara,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Hepatology research : the official journal of the Japan Society of Hepatology　51　2　190　2021/02
　Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy.　Yoshio Sakai,Shinya Fukunishi,Masayuki Takamura,Kazunori Kawaguchi,Oto Inoue,Soichiro Usui,Shinichiro Takashima,Akihiro Seki,Akira Asai,Yusuke Tsuchimoto,Alessandro Nasti,Tuyen Thuy Bich Ho,Yasuhito Imai,Kenichi Yoshimura,Toshinori Murayama,Taro Yamashita,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Takashi Wada,Kenichi Harada,Kazuhide Higuchi,Shuichi Kaneko　Regenerative therapy　18　97　2021/12
　Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease.　Kazunori Kawaguchi,Yoshio Sakai,Takeshi Terashima,Tetsuhiro Shimode,Akihiro Seki,Noriaki Orita,Yumie Takeshita,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Kazuya Kitamura,Taro Yamashita,Tatsuya Yamashita,Masayuki Takamura,Eishiro Mizukoshi,Toshinari Takamura,Masao Honda,Takashi Wada,Shuichi Kaneko　Medicine　100　31　e26835　2021/08/06
　BMP9-ID1 signaling promotes EpCAM-positive cancer stem cell properties in hepatocellular carcinoma.　Han Chen,Kouki Nio,Taro Yamashita,Hikari Okada,Ru Li,Tsuyoshi Suda,Yingyi Li,Phuong Thi Bich Doan,Akihiro Seki,Hidetoshi Nakagawa,Tadashi Toyama,Takeshi Terashima,Noriho Iida,Tetsuro Shimakami,Hajime Takatori,Kazunori Kawaguchi,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Molecular oncology　15　8　2203　2021/08
　Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice.　Kosuke Ishida,Akihiro Seki,Kazunori Kawaguchi,Alessandro Nasti,Masatoshi Yamato,Hiiro Inui,Takuya Komura,Taro Yamashita,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Takashi Wada,Kenichi Harada,Shuichi Kaneko,Yoshio Sakai　Stem cell research　54　102425　2021/07
　Serum Laminin γ2 Monomer as a Diagnostic and Predictive Biomarker for Hepatocellular Carcinoma.　Taro Yamashita,Naohiko Koshikawa,Tetsuro Shimakami,Takeshi Terashima,Masatoshi Nakagawa,Kouki Nio,Rika Horii,Noriho Iida,Kazunori Kawaguchi,Kuniaki Arai,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Azusa Kitao,Satoshi Kobayashi,Shizuko Takahara,Yasuhito Imai,Kenichi Yoshimura,Toshinori Murayama,Yasunari Nakamoto,Eisaku Yoshida,Toru Yoshimura,Motoharu Seiki,Shuichi Kaneko　Hepatology (Baltimore, Md.)　74　2　760　2021/08
　Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up.　Yoshio Sakai,Alessandro Nasti,Yumie Takeshita,Miki Okumura,Shinji Kitajima,Masao Honda,Takashi Wada,Seiji Nakamura,Toshinari Takamura,Takuro Tamura,Kenichi Matsubara,Shuichi Kaneko　Scientific reports　11　1　16564　2021/08/16
　Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics.　Mayumi Nagashimada,Masao Honda　International journal of molecular sciences　22　15　2021/07/27
　The characteristics of the immune cell profiles in peripheral blood in cholangiocarcinoma patients.　Akihiko Kida,Eishiro Mizukoshi,Hidenori Kido,Tadashi Toyama,Takeshi Terashima,Kuniaki Arai,Tatsuya Yamashita,Kazumi Fushimi,Taro Yamashita,Yoshio Sakai,Masao Honda,Akio Uchiyama,Akito Sakai,Koichi Shimizu,Shuichi Kaneko　Hepatology international　15　3　695　2021/06
　Effect of adoptive T-cell immunotherapy on immunological parameters and prognosis in patients with advanced pancreatic cancer.　Tatsuo Kumai,Eishiro Mizukoshi,Tomomi Hashiba,Hidetoshi Nakagawa,Masaaki Kitahara,Tomoharu Miyashita,Takafumi Mochizuki,Shigenori Goto,Takashi Kamigaki,Rishu Takimoto,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Katsuro Tomita,Shuichi Kaneko　Cytotherapy　23　2　137　2021/02
　Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis.　Noriho Iida,Eishiro Mizukoshi,Tatsuya Yamashita,Masahiro Yutani,Jun Seishima,Ziyu Wang,Kuniaki Arai,Hikari Okada,Taro Yamashita,Yoshio Sakai,Yusuke Masuo,Rina Agustina,Yukio Kato,Yukako Fujinaga,Masanobu Oshima,Masao Honda,François Lebreton,Michael S Gilmore,Shuichi Kaneko　Nature cancer　2　10　1039　2021/10
　Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma　Tsuyoshi Suda,Taro Yamashita,Hajime Sunagozaka,Hikari Okada,Kouki Nio,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　International Journal of Molecular Sciences　23　5　2801　2022/03/03　
　Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut.　Hirofumi Okafuji,Noriho Iida,Kazuya Kitamura,Jun Seishima,Ziyu Wang,Masahiro Yutani,Takatoshi Yoshio,Taro Yamashita,Yoshio Sakai,Masao Honda,Tatsuya Yamashita,Yukako Fujinaga,Reiko Shinkura,Yasuhito Hamaguchi,Eishiro Mizukoshi,Shuichi Kaneko　Digestion　1　2022/02/18
　Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8+ T cells.　Eishiro Mizukoshi,Hidetoshi Nakagawa,Toshikatsu Tamai,Masaaki Kitahara,Kazumi Fushimi,Kouki Nio,Takeshi Terashima,Noriho Iida,Kuniaki Arai,Tatsuya Yamashita,Taro Yamashita,Yoshio Sakai,Masao Honda,Shuichi Kaneko　Nature communications　13　1　3123　2022/06/03
　A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes.　Ariunaa Sumiyadorj,Kazuhisa Murai,Tetsuro Shimakami,Kazuyuki Kuroki,Tomoki Nishikawa,Masaki Kakuya,Atsumu Yamada,Ying Wang,Atsuya Ishida,Takayoshi Shirasaki,Shotaro Kawase,Ying-Yi Li,Hikari Okada,Kouki Nio,Kazunori Kawaguchi,Taro Yamashita,Yoshio Sakai,Davaadorj Duger,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Hepatology communications　2022/06/12
　FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition.　Ru Li,Hikari Okada,Taro Yamashita,Kouki Nio,Han Chen,Yingyi Li,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　International journal of molecular sciences　23　15　2022/07/27
　肝細胞腺腫の新たな亜型の同定(Identification of a new subtype of hepatocellular adenoma)　岩淵禎弘,川口和紀,本多政夫,橋本真一　日本癌学会総会記事　81回　P　2022/09
　Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals.　Shihui Li,Eishiro Mizukoshi,Kazunori Kawaguchi,Miyabi Miura,Michiko Nishino,Tetsuro Shimakami,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko　International journal of molecular sciences　23　19　2022/10/01
　Plasma Antithrombin III Levels Can Be a Prognostic Factor in Liver Cirrhosis Patients with Portal Vein Thrombosis　Tsuyoshi Suda,Hajime Takatori,Takehiro Hayashi,Kiichiro Kaji,Kouki Nio,Takeshi Terashima,Tetsuro Shimakami,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Kenichiro Okumura,Kazuto Kozaka,Taro Yamashita　International Journal of Molecular Sciences　24　9　2023/04　
　Efficacy of a novel self-expandable metal stent with dumbbell-shaped flare ends for distal biliary obstruction due to unresectable pancreatic cancer.　Masaki Miyazawa,Hajime Takatori,Hirofumi Okafuji,Tomoyuki Hayashi,Tadashi Toyama,Shinya Yamada,Kazuya Kitamura,Kuniaki Arai,Yoshio Sakai,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　Scientific reports　12　1　21100　2022/12/06
　BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma　Han Chen,Kouki Nio,Hong Tang,Taro Yamashita,Hikari Okada,Yingyi Li,Phuong Thi Bich Doan,Ru Li,Junyan Lv,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko　International Journal of Molecular Sciences　23　3　1475　2022/01/27　
　Comparison of Tofogliflozin and Glimepiride Effects on Nonalcoholic Fatty Liver Disease in Participants With Type 2 Diabetes: A Randomized, 48-Week, Open-Label, Active-Controlled Trial.　Yumie Takeshita,Masao Honda,Kenichi Harada,Yuki Kita,Noboru Takata,Hiromasa Tsujiguchi,Takeo Tanaka,Hisanori Goto,Yujiro Nakano,Noriho Iida,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Hiroyuki Nakamura,Shuichi Kaneko,Toshinari Takamura　Diabetes care　45　9　2064　2022/09/01
　Preexisting Humoral Immunity Cross-Reacting with SARS-CoV-2 Might Prevent Death Due to COVID-19 in Critical Patients　Taro Yamashita,Tetsuro Shimakami,Kouki Nio,Takeshi Terashima,Masaki Okajima,Takumi Taniguchi,Takashi Wada,Masao Honda,Toshifumi Gabata,Kenji Ota,Katsunori Yanagihara,Shuichi Kaneko　Journal of Clinical Medicine　11　13　3870　2022/07/04　
　Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair.　Masaaki Yano,Alessandro Nasti,Akihiro Seki,Kosuke Ishida,Masatoshi Yamato,Hiiro Inui,Norihiko Ogawa,Shingo Inagaki,Tuyen Thuy Bich Ho,Kazunori Kawaguchi,Taro Yamashita,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Oto Inoue,Shinichiro Takashima,Soichiro Usui,Masayuki Takamura,Masao Honda,Takashi Wada,Shuichi Kaneko,Yoshio Sakai　Regenerative therapy　18　497　2021/12
　Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits Hepatitis B Virus infection and replication.　Mayuko Ide,Noriko Tabata,Yuko Yonemura,Takayoshi Shirasaki,Kazuhisa Murai,Ying Wang,Atsuya Ishida,Hikari Okada,Masao Honda,Shuichi Kaneko,Nobuhide Doi,Satoru Ito,Hiroshi Yanagawa　The Journal of biological chemistry　298　7　102097　2022/06/02
　Hepatitis B virus utilizes a retrograde trafficking route via the trans-Golgi network to avoid lysosomal degradation.　Ying-Yi Li,Kazuyuki Kuroki,Tetsuro Shimakami,Kazuhisa Murai,Kazunori Kawaguchi,Takayoshi Shirasaki,Kouki Nio,Saiho Sugimoto,Tomoki Nishikawa,Hikari Okada,Noriaki Orita,Hideo Takayama,Ying Wang,Phuong Doan Thi Bich,Astuya Ishida,Sadahiro Iwabuchi,Shinichi Hashimoto,Takeshi Shimaoka,Noriko Tabata,Miho Watanabe-Takahashi,Kiyotaka Nishikawa,Hiroshi Yanagawa,Motoharu Seiki,Kouji Matsushima,Taro Yamashita,Shuichi Kaneko,Masao Honda　Cellular and molecular gastroenterology and hepatology　15　3　533　2022/10/18
　Upregulation of the Long Noncoding RNA HULC by Hepatitis C Virus and Its Regulation of Viral Replication　Kitabayashi J, Shirasaki T, Shimakami T, Nishiyama T, Welsch C, Funaki M, Murai K, Sumiyadorj A, Takatori H, Kitamura K, Kawaguchi K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S; Hokuriku Liver Study Group.　J Infect Dis.　226　3　407　2022/08/26
　Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair.　Yano M, Nasti A, Seki A, Ishida K, Yamato M, Inui H, Ogawa N, Inagaki S, Ho TTB, Kawaguchi K, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Inoue O, Takashima S, Usui S, Takamura M, Honda M, Wada T, Kaneko S, Sakai Y.　Regen Ther.　18　497-507　2021/12/03
　Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis.　Iida N, Mizukoshi E, Yamashita T, Yutani M, Seishima J, Wang Z, Arai K, Okada H, Yamashita T, Sakai Y, Masuo Y, Agustina R, Kato Y, Fujinaga Y, Oshima M, Honda M, Lebreton F, Gilmore MS, Kaneko S.　Nat Cancer.　2　10　1039-1054　2021/10/01
　Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants.　Yoshida K, Desbiolles A, Feldman SF, Ahn SH, Alidjinou EK, Atsukawa M, Bocket L, Brunetto MR, Buti M, Carey I, Caviglia GP, Chen EQ, Cornberg M, Enomoto M, Honda M, Zu Siederdissen CH, Ishigami M, Janssen HLA, Maasoumy B, Matsui T, Matsumoto A, Nishiguchi S, Riveiro-Barciela M, Takaki A, Tangkijvanich P, Toyoda H, van Campenhout MJH, Wang B, Wei L, Yang HI, Yano Y, Yatsuhashi H, Yuen MF, Tanaka E, Lemoine M, Tanaka Y, Shimakawa Y.　Clin Gastroenterol Hepatol　19　1　46-60　2021/01/01
　Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis.　Ho TTB, Nasti A, Seki A, Komura T, Inui H, Kozaka T, Kitamura Y, Shiba K, Yamashita T, Yamashita T, Mizukoshi E, Kawaguchi K, Wada T, Honda M, Kaneko S, Sakai Y.　J Immunother Cancer. 　8　2　e001367　2020/11/01
　Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial　Yoshio Sakai, Shinya Fukunishi, Masayuki Takamura, Oto Inoue, Shinichiro Takashima, Soichiro Usui, Akihiro Seki, Alessandro Nasti, Tuyen Thuy Bich Ho, Kazunori Kawaguchi, Akira Asai, Yusuke Tsuchimoto, Taro Yamashita, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuhito Imai, Kenichi Yoshimura, Toshinori Murayama, Takashi Wada, Kenichi Harada, Kazuhide Higuchi, Shuichi Kaneko　JMIR Res Protoc　9　3　e17904　2020/03/31
　Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.　Yamato M, Sakai Y, Mochida H, Kawaguchi K, Takamura M, Usui S, Seki A, Mizukoshi E, Yamashita T, Yamashita T, Ishida K, Nasti A, Tuyen HTB, Komura T, Yoshida K, Wada T, Honda M, Kaneko S.　J Gastroenterol Hepatol.　34　8　1432-1440　2019/08/01
　Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells.　Sakai Y, Honda M, Matsui S, Komori O, Murayama T, Fujiwara T, Mizuno M, Imai Y, Yoshimura K, Nasti A, Wada T, Iida N, Kitahara M, Horii R, Toshikatsu T, Nishikawa M, Okafuji H, Mizukoshi E, Yamashita T, Yamashita T, Arai K, Kitamura K, Kawaguchi K, Takatori H, Shimakami T, Terashima T, Hayashi T, Nio K, Kaneko S; Hokuriku Liver Study Group.　Cancer Sci.　110　4　1364-1388　2019/04/01
　Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.　Kanno M, Kawaguchi K, Honda M, Horii R, Takatori H, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.　J Gastroenterol.　54　6　549-557　2019/06/01
　A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma.　Tamai T, Mizukoshi E, Kumagai M, Terashima T, Iida N, Kitahara M, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Honda M, Fushimi K, Kaneko S.　Sci Rep　10　1　4021　2020/03/04
　Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.　Nishikawa T, Nagata N, Shimakami T, Shirakura T, Matsui C, Ni Y, Zhuge F, Xu L, Chen G, Nagashimada M, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S, Ota T.　Sci Rep.　10　1　815　2020/01/21
　Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host.　Seishima J, Iida N, Kitamura K, Yutani M, Wang Z, Seki A, Yamashita T, Sakai Y, Honda M, Yamashita T, Kagaya T, Shirota Y, Fujinaga Y, Mizukoshi E, Kaneko S.　Genome Biol　20　1　252　2019/12/25
　MicroRNA‐10a Impairs Liver Metabolism in Hepatitis C Virus‐Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator‐Like 1.　Horii R, Honda M*, Shirasaki T, Shimakami T, Shimizu R, Yamanaka S, Murai K, Kawaguchi K, Arai K, Yamashita T, Sakai Y, Yamashita T, Okada H, Nakamura M, Mizukoshi E, Kaneko S.　Hepatol Commun　3　12　1687-1703　2019/09/26
　Characteristics of Impaired Dendritic Cell Function in Patients With Hepatitis B Virus Infection.　Yonejima A, Mizukoshi E, Tamai T, Nakagawa H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Okada H, Yamashita T, Sakai Y, Honda M, Kaneko S.　Hepatology　70　1　25-39　2019/07/01
　Establishment and Characterization of a New Cell Line Permissive for Hepatitis C Virus Infection. Sci Rep accepted in press.　Omura H, Liu F, Shimakami T, Murai K, Shirasaki T, Kitabayashi T, Funaki M, Nishikawa T, Nakai R, Sumiyadorj A, Hayashi T, Yamashita , Honda H, Kaneko S. 　Sci Rep.　9　1　7943　2019/05/28
　Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation.　Fujinaga H, Sakai Y, Yamashita T, Arai K, Terashima T, Komura T, Seki A, Kawaguchi K, Nasti A, Yoshida K, Wada T, Yamamoto K, Kume K, Hasegawa T, Takata T, Honda M, Kaneko S.　Int J Radiat Biol.　95　5　571-579　2019/05/01
　Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.　Terashima T, Yamashita T, Toyama T, Arai K, Kawaguchi K, Kitamura K, Yamashita 　Liver Cancer.　8　2　130-139　2019/03/01
　Immune responses against tumour-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients.　Kida A, Mizukoshi E, Tamai T, Terashima T, Kitahara M, Arai K, Yamashita T, Fushimi K, Honda M, Kaneko S.　Liver Int.　38　11　2040-2050　2018/11/01
　Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: prospects for regorafenib therapy.　Terashima T, Yamashita T, Sunagozaka H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Hepatol Res.　48　12　956-966　2018/11/01
　Three renal failure cases successfully treated with ombitasvir/paritaprevir/ritonavir for genotype 1b hepatitis C virus reinfection after liver transplantation.　Orita N, Shimakami T, Sunagozaka H, Horii R, Nio K, Terashima T, Iida N, Kitahara M, Takatori H, Kawaguchi K, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S.　Clin J Gastroenterol.　12　1　63-70　2019/02/01
　Characteristics of immune response to tumor-associated antigens and immune cell profile in hepatocellular carcinoma patients.　Inada Y, Mizukoshi E, Seike T, Tamai T, Iida N, Kitahara M, Yamashita T, Arai K, Terashima T, Fushimi K, Yamashita T, Honda M, Kaneko S.　Hepatology.　69　2　653-665　2019/02/01
　Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.　Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano K, Masaki N, Sugauchi F, Izumi N, Tokunaga K, Mizokami M　Nat Genet.　41　10　1105-9　2009/10/01
　Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation.　Fujinaga H, Sakai Y, Yamashita T, Arai K, Terashima T, Komura T, Seki A, Kawaguchi K, Nasti A, Yoshida K, Wada T, Yamamoto K, Kume K, Hasegawa T, Takata T, Honda M, Kaneko S.　Int J Radiat Biol.　Epub ahead of print　2018/12/17
　Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis Diagnosis of NASH using serum fatty acid.　Yamada K, Mizukoshi E, Seike T, Horii R, Terashima T, Iida N, Kitahara M, Sunagozaka H, Arai K, Yamashita T, Honda M, Takamura T, Harada K, Kaneko S.　J Gastroenterol Hepatol.　Epub ahead of print　2019/03/12
　Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis.　Satoh S, Onomura D, Ueda Y, Dansako H, Honda M, Kaneko S, Kato N.　Biochem J.　476　1　137-149　2019/01/15
　POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.　Hitomi Y, ほか85名、50番目　Sci Rep.　9　1　102　2019/01/14
　Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models.　Sakai Y, Miyazawa M, Komura T, Yamada T, Nasti A, Yoshida K, Takabatake H, Yamato M, Yamashita T, Yamashita T, Mizukoshi E, Okuzono M, Ho TTB, Kawaguchi K, Wada T, Honda M, Kaneko S.　Cancer Sci.　110　3　903-912　2019/03/01
　Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation.　Wang Z, Kawaguchi K, Honda M, Hashimoto S, Shirasaki T, Okada H, Orita N, Shimakami T, Yamashita T, Sakai Y, Mizukoshi E, Murakami S, Kaneko S.　Sci Rep.　9　1　1621　2019/02/07
　The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.　Shirasaki T, Honda M, Yamashita T, Nio K, Shimakami T, Shimizu R, Nakasyo S, Murai K, Shirasaki N, Okada H, Sakai Y, Sato T, Suzuki T, Yoshioka K, Kaneko S.　Sci Rep.　8　1　13143　2018/09/03
　Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood.　Komura T, Yano M, Miyake A, Takabatake H, Miyazawa M, Ogawa N, Seki A, Honda M, Wada T, Matsui S, Kaneko S, Sakai Y.　Can J Gastroenterol Hepatol.　2018　7436205　2018/06/11
　Distinct notch signaling expression patterns between nucleoside and nucleotide analogues treatment for hepatitis B virus infection.　Wang Z, Kawaguchi K, Honda M, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.　Biochem Biophys Res Commun.　501　3　682-687　2018/06/27
　Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.　Sawai H, Nishida N, Khor SS, Honda M, Sugiyama M, Baba N, Yamada K, Sawada N, Tsugane S, Koike K, Kondo Y, Yatsuhashi H, Nagaoka S, Taketomi A, Fukai M, Kurosaki M, Izumi N, Kang JH, Murata K, Hino K, Nishina S, Matsumoto A, Tanaka E, Sakamoto N, Ogawa K, Yamamoto K, Tamori A, Yokosuka O, Kanda T, Sakaida I, Itoh Y, Eguchi Y, Oeda S, Mochida S, Yuen MF, Seto WK, Poovorawan Y, Posuwan N, Mizokami M, Tokunaga K.　Sci Rep.　8　1　7958　2018/05/21
　Immune responses of human T lymphocytes to novel hepatitis B virus-derived peptides.　Yamamiya D, Mizukoshi E, Kaji K, Terashima T, Kitahara M, Yamashita T, Arai K, Fushimi K, Honda M, Kaneko S.　PLoS One.　13　6　e0198264　2018/06/01
　Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B.　Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S.　J Gastroenterol.　53　6　740-751　2018/06/01
　Unexpected Replication Boost by Simeprevir for Simeprevir-resistant Variants in Genotype 1a Hepatitis C Virus.　Murai K, Shimakami T, Welsch C, Shirasaki T, Liu F, Kitabayashi J, Tanaka S, Funaki M, Omura H, Nishikawa T, Suminyadorj A, Honda M, Kaneko S.　Antimicrob Agents Chemother　62　7　e02601-17　2018/06/26
　Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection.　Murata K, Asano M, Matsumoto A, Sugiyama M, Nishida N, Tanaka E, Inoue T, Sakamoto M, Enomoto N, Shirasaki T, Honda M, Kaneko S, Gatanaga H, Oka S, Kawamura YI, Dohi T, Shuno Y, Yano H, Mizokami M.　Gut　67　362-371　2018/01/01
　Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease.　Yamada K, Mizukoshi E, Seike T, Horii R, Kitahara M, Sunagozaka H, Arai K, Yamashita T, Honda M, Kaneko S.　PLoS One　13　e0191026　2018/01/01
　Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro.　Murai K, Shirasaki T, Honda M, Shimizu R, Shimakami T, Nakasho S, Shirasaki N, Okada H, Sakai Y, Yamashita T, Kaneko S.　Int J Mol Sci　19　108　2017/04/01
　The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells.　Nasti A, Sakai Y, Seki A, Buffa GB, Komura T, Mochida H, Yamato M, Yoshida K, Ho TTB, Takamura M, Usui S, Wada T, Honda M, Kaneko S.　Eur J Immunol　47　2163-2174　2017/04/01
　Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study.　Hayashi T, Yamashita T, Terashima T, Suda T, Okada H, Asahina Y, Hayashi T, Hara Y, Nio K, Sunagozaka H, Takatori H, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S.　BMC Cancer　17　870　2017/04/01
　Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo.　Funaki M, Kitabayashi J, Shimakami T, Nagata N, Sakai Y, Takegoshi K, Okada H, Murai K, Shirasaki T, Oyama T, Yamashita T, Ota T, Takuwa Y, Honda M, Kaneko S.　Sci Rep　7　16978　2017/04/01
　Reactivation of Hepatitis B Virus from an isolated Anti-HBc positive patient after eradication of Hepatitis C Virus with Direct-acting Antiviral Agents.　Suda T, Shimakami T, Shirasaki T, Yamashita T, Mizukoshi E, Honda M, Kaneko S.　J Hepatol　67　1108-1111　2017/04/01
　Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma.　Komura T, Takabatake H, Harada K, Yamato M, Miyazawa M, Yoshida K, Honda M, Wada T, Kitagawa H, Ohta T, Kaneko S, Sakai Y.　Cancer Sci　108　2122-2129　2017/04/01
　Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma.　Hayashi T, Yamashita T, Okada H, Nio K, Hara Y, Nomura Y, Hayashi T, Asahina Y, Yoshida M, Oishi N, Sunagozaka H, Takatori H, Honda M, Kaneko S.　Cancer Cell Int　17　97　2017/04/01
　The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis.　Enomoto H, Tao L, Eguchi R, Sato A, Honda M, Kaneko S, Iwata Y, Nishikawa H, Imanishi H, Iijima H, Tsujimura T, Nishiguchi S.　Sci Rep　7　12189　2017/04/01
　Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. 　Matsuura K, Sawai H, Ikeo K, Ogawa S, Iio E, Isogawa M, Shimada N, Komori A, Toyoda H, Kumada T, Namisaki T, Yoshiji H, Sakamoto N, Nakagawa M, Asahina Y, Kurosaki M, Izumi N, Enomoto N, Kusakabe A, Kajiwara E, Itoh Y, Ide T, Tamori A, Matsubara M, Kawada N, Shirabe K, Tomita E, Honda M, Kaneko S, Nishina S, Suetsugu A, Hiasa Y, Watanabe H, Genda T, Sakaida I, Nishiguchi S, Takaguchi K, Tanaka E, Sugihara J, Shimada M, Kondo Y, Kawai Y, Kojima K, Nagasaki M, Tokunaga K, Tanaka Y; Japanese Genome-Wide Association Study Group for Viral Hepatitis.　Gastroenterology.　Epub ahead of print　2017/02/02
　Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib.　Terashima T, Yamashita T, Takata N, Nakagawa H, Toyama T, Arai K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Hepatol Res.　46　7　650-6　2016/06/01
　HBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics.　Kawaguchi K, Honda M, Kaneko S.　Transl Cancer Res　5　S2　S216-220　2016/04/01
　Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication.　Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.　Acta Med Okayama.　70　2　75-88　2016/04/01
　A Novel mTOR Inhibitor; Anthracimycin for the Treatment of Human Hepatocellular Carcinoma　Hayashi T, Yamashita T, Okada H, Oishi N, Sunagozaka H, Nio K, Hayashi T, Hara Y, Asahina Y, Yoshida M, Hashiba T, Suda T, Shirasaki T, Igarashi Y, Miyanouchi K, Yamashita T, Honda M, Kaneko S. 　Anticancer Res　37　7　3397-3403　2017/07/01
　Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet.　Okada H, Takabatake R, *Honda M, Takegoshi K, Yamashita T, Nakamura M, Shirasaki T, Sakai Y, Shimakami T, Nagata N, Takamura T, Tanaka T, Kaneko S.　Oncotarget　8　39978-39993　2017/04/01
　Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α.　Satoh S, Mori K, Onomura D, Ueda Y, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.　Hepatol Commun　1　550-563　2017/04/01
　Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis.　Nishida N, Ohashi J, Khor SS, Sugiyama M, Tsuchiura T, Sawai H, Hino K, Honda M, Kaneko S, Yatsuhashi H, Yokosuka O, Koike K, Kurosaki M, Izumi N, Korenaga M, Kang JH, Tanaka E, Taketomi A, Eguchi Y, Sakamoto N, Yamamoto K, Tamori A, Sakaida I, Hige S, Itoh Y, Mochida S, Mita E, Takikawa Y, Ide T, Hiasa Y, Kojima H, Yamamoto K, Nakamura M, Saji H, Sasazuki T, Kanto T, Tokunaga K, Mizokami M.　Sci Rep.　6　24767　2016/04/19
　Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes.　Honda M, Shirasaki T, Shimakami T, Sakai A, Horii R, Arai K, Yamashita T, Sakai Y, Yamashita T, Okada H, Murai K, Nakamura M, Mizukoshi E and Kaneko S.　Hepatology　59　3　828-38　2014/03/01
　De Novo Emergence of Mesenchymal Stem-Like CD105+ Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma.　Nomura Y, Yamashita T, Oishi N, Nio K, Hayashi T, Yoshida M, Hayashi T, Hashiba T, Asahina Y, Okada H, Sunagozaka H, Takatori H, Honda M, Kaneko S.　Transl Oncol　10　2　184-189　2017/04/01
　Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants. 　Yamane D, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM.　Nucleic Acids Res.　Epub ahead of print　2017/01/12
　Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma.　Yamashita T, Horii R, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　BMC Cancer.　16　1　338　2016/05/31
　Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma.　Honda M, Yamashita T, Yamashita T, Arai K, Sakai Y, Sakai A, Nakamura M, Mizukoshi E, Kaneko S.　15　13　191　2013/04/01
　Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population. 　Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Nakamura H, Tanaka A, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Abe M, Nakao K, Yamagiwa S, Kaneko S, Honda M, Umemura T, Ichida T, Seike M, Sakisaka S, Harada M, Yokosuka O, Ueno Y, Senju M, Kanda T, Shibata H, Himoto T, Murata K, Miyake Y, Ebinuma H, Taniai M, Joshita S, Nikami T, Ota H, Kouno H, Kouno H, Nakamuta M, Fukushima N, Kohjima M, Komatsu T, Komeda T, Ohara Y, Muro T, Yamashita T, Yoshizawa K, Nakamura Y, Shimada M, Hirashima N, Sugi K, Ario K, Takesaki E, Naganuma A, Mano H, Yamashita H, Matsushita K, Yamauchi K, Makita F, Nishimura H, Furuta K, Takahashi N, Kikuchi M, Masaki N, Tanaka T, Tamura S, Mori A, Yagi S, Shirabe K, Komori A, Migita K, Ito M, Nagaoka S, Abiru S, Yatsuhashi H, Yasunami M, Shimoda S, Harada K, Egawa H, Maehara Y, Uemoto S, Kokudo N, Takikawa H, Ishibashi H, Chayama K, Mizokami M, Nagasaki M, Tokunaga K, Nakamura M.　Hum Mol Genet.　Epub ahead of print　2017/01/05
　Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C. 　Iio E, Matsuura K, Nishida N, Maekawa S, Enomoto N, Nakagawa M, Sakamoto N, Yatsuhashi H, Kurosaki M, Izumi N, Hiasa Y, Masaki N, Ide T, Hino K, Tamori A, Honda M, Kaneko S, Mochida S, Nomura H, Nishiguchi S, Okuse C, Itoh Y, Yoshiji H, Sakaida I, Yamamoto K, Watanabe H, Hige S, Matsumoto A, Tanaka E, Tokunaga K, Tanaka Y. 　Hum Genet.　134　3　279-89　2015/03/01
　P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.　Terashima T, Mizukoshi E, Arai K, Yamashita T, Yoshida M, Ota H, Onishi I, Kayahara M, Ohtsubo K, Kagaya T, Honda M, Kaneko S.　Cancer Immunol Immunother.　63　5　479-89　2014/05/01
　Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems.　Liu F, Shimakami T, Murai K, Shirasaki T, Funaki M, Honda M, Murakami S, Yi M, Tang H, Kaneko S.　Sci Rep.　6　30939　2016/04/03
　Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model. 　Takegoshi K, Honda M, Okada H, Takabatake R, Matsuzawa-Nagata N, Campbell JS, Nishikawa M, Shimakami T, Shirasaki T, Sakai Y, Yamashita T, Takamura T, Tanaka T, Kaneko S.　Oncotarget.　Epub ahead of print　2017/02/13
　Response to chemotherapy improved hepatic reserve for patients with hepatocellular carcinoma and Child-Pugh B cirrhosis.　Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Cancer Sci.　107　9　1263-9　2016/09/01
　Altered gene expression in T-cell receptor signalling in peripheral blood leucocytes in acute coronary syndrome predicts secondary coronary events.　Takashima S, Usui S, Kurokawa K, Kitano T, Kato T, Murai H, Furusho H, Oda H, Maruyama M, Nagata Y, Usuda K, Kubota K, Takeshita Y, Sakai Y, Honda M, Kaneko S, Takamura M.　Open Heart.　3　1　e000400　2016/06/30
　Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma.　Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Liver Cancer　6　236-249　2017/04/01
　Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer.　Kawaguchi K, Honda M, Yamashita T, Okada H, Shirasaki T, Nishikawa M, Nio K, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.　Am J Pathol.　186　8　2055-67　2016/06/14
　Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma.　Honda M, Shirasaki T, Terashima T, Kawaguchi K, Nakamura M, Oishi N, Wang X, Shimakami T, Okada H, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.　J Infect Dis.　213　7　1096-106　2016/04/01
　Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B.　Wang X, Oishi N, Shimakami T, Yamashita T, Honda M, Murakami S, Kaneko S.　World J Gastroenterol.　23　3252-3261　2017/04/01
　MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells.　Shirasaki T, Honda M, Shimakami T, Horii R, Yamashita T, Sakai Y, Sakai A, Okada H, Watanabe R, Murakami S, Yi M, Lemon SM, Kaneko S.　J Virol.　87　9　5270-86　2013/05/01
　Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib.　Terashima T, Yamashita T, Takata N, Nakagawa H, Toyama T, Arai K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Hepatol Res.　2015/10/01
　Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.　Okada H, Honda M, Campbell JS, Takegoshi K, Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S.　Cancer Sci.　106　9　1143-52　2015/06/01
　Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy.　Terashima T, Yamashita T, Iida N, Yamashita T, Nakagawa H, Arai K, Kitamura K, Kagaya T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.　Hepatol Res.　45　9　949-59　2015/09/01
　Inflammatory features of pancreatic cancer highlighted by monocytes/macrophages and CD4+ T cells with clinical impact.　Komura T, Sakai Y, Harada K, Kawaguchi K, Takabatake H, Kitagawa H, Wada T, Honda M, Ohta T, Nakanuma Y, Kaneko S.　Cancer Sci.　106　6　672-86　2015/06/01
　Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis.　Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S.　Liver Int.　35　6　1773　2015/06/01
　Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma.　Nio K, Yamashita T, Okada H, Kondo M, Hayashi T, Hara Y, Nomura Y, Zeng SS, Yoshida M, Hayashi T, Sunagozaka H, Oishi N, Honda M, Kaneko S. 　J Hepatol.　63　5　1164-72　2015/11/01
　Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.　Okada H, Honda M, Campbell JS, Takegoshi K, Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S.　Cancer Sci.　106　9　1143-52　2015/09/01
　Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs.　Selitsky SR, Dinh TA, Toth CL, Kurtz CL, Honda M, Struck BR, Kaneko S, Vickers KC, Lemon SM, Sethupathy P.　MBio.　6　6　e01500-15　2015/12/08
　TSU-68 Ameliorates Hepatocellular Carcinoma Growth by Inhibiting Microenvironmental Platelet-derived Growth Factor Signaling.　Hara Y, Yamashita T, Oishi N, Nio K, Hayashi T, Nomura Y, Yoshida M, Hayashi T, Hashiba T, Asahina Y, Kondo M, Okada H, Sunagozaka H, Honda M, Kaneko S.　Anticancer Res.　35　3　1423-31　2015/03/01
　Association of Interleukin 28B genotype and hepatocellular carcinoma recurrence in patients with chronic hepatitis C.　Hodo Y, Honda M, Tanaka A, Nomura Y, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Sakai A, Sasaki M, Nakanuma Y, Moriyama M, Kaneko S.　Clin Cancer Res.　19　7　1827-37　2013/04/01
　Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling.　Ueda T, Honda M, Horimoto K, Aburatani S, Saito S, Yamashita T, Sakai Y, Nakamura M, Takatori H, Sunagozaka H, Kaneko S.　Genomics.　101　4　238-48　2013/04/01
　ER stress induced impaired TLR signaling and macrophage differentiation of human monocytes.　Komura T, Sakai Y, Honda M, Takamura T, Wada T, Kaneko S.　Cell Immunol.　282　1　44-52　2013/04/24
　Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway. 　Shirasaki T, Honda M, Shimakami T, Murai K, Shiomoto T, Okada H, Takabatake R, Tokumaru A, Sakai Y, Yamashita T, Lemon SM, Murakami S, Kaneko S. 　Hepatology　60　5　1519-30　2014/11/01
　Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma.　Yamashita T, Kitao A, Matsui O, Hayashi T, Nio K, Kondo M, Ohno N, Miyati T, Okada H, Yamashita T, Mizukoshi M, Honda M, Nakanuma Y, Takamura H, Ohta T, Nakamoto Y, Yamamoto M, Takayama T, Arii S, Wang XW, Kaneko S.　Hepatology　60　5　1674-85　2014/11/01
　Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B.　Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S.　J Gastroenterol. 　Epub ahead of print　2017/08/01
　Pure red cell aplasia associated with concomitant use of mycophenolate mofetil and ribavirin in post-transplant recurrent hepatitis C.　Hodo Y, Tsuji K, Mizukoshi E, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S　TRANSPLANT INTERNATIONAL　19　2　170-1　2006/02
　Prognosis of autoimmune hepatitis showing acute presentation　Yamamoto, Kazuhide; Miyake, Yasuhiro; Ohira, Hiromasa; Suzuki, Yoshiyuki; Zeniya, Mikio; Onji, Morikazu Morikazu; Tsubouchi, Hirohito; Yoshizawa, Kaname; Morizane, Toshio; Hibi, Toshifumi; Aoyagi, Yutaka; Nakanuma, Yasuni; Hirohara, Junko; Takikawa, Hajime; Ishibashi, Hiromi; Shimoda, Shinji; Sakisaka, Shotaro; Nakamuta, Makoto; Matsuzaki, Yasushi; Saibara, Toshiji; Ueno, Yoshiyuki; Miyakawa, Hiroshi; Kokudo, Norihiro; Egawa, Hiroto; Maehara, Yoshihiko; Mochida, Satoshi; Sakaida, Isao; Fujisawa, Tomoo; Suzuki, Kazuyuki; Inoue, Kazuaki; Ichida, Takafumi; Yokosuka, Osamu; Fukui, Hiroshi; Moriwaki, Hisataka; Mori, Mitsuru; Mori, Toshiyuki; Nagino, Masato; Sata, Naohiro; Tazuma, Susumu; Yasaka, Takahiro; Tsuyuguchi, Toshio; Shoda, Junichi; Honda, Masao; Yamaue, Hiroki; Unno, Michiaki; Hayashi, Norio　Hepatology Research　43　6　630-638　2013/06/01　
　Endothelial to mesenchymal transition via transforming growth factor-beta1/Smad activation is associated with portal venous stenosis in idiopathic portal hypertension.　Kitao A, Sato Y, Sawada-Kitamura S, Harada K, Sasaki M, Morikawa H, Shiomi S, Honda M, Matsui O, Nakanuma Y　AMERICAN JOURNAL OF PATHOLOGY　175　2　616-26　2009/08
　Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation.　Yamashita T, Honda M, Nio K, Nakamoto Y, Yamashita T, Takamura H, Tani T, Zen Y, Kaneko S　CANCER RESEARCH　70　11　4687-97　2010/06
　Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma　Yamashita, Taro; Honda, Masao; Nakamoto, Yasunari; Baba, Masayo; Nio, Kouki; Hara, Yasumasa; Zeng, Shasha; Hayashi, Takehiro; Kondo, Mitsumasa; Takatori, Hajime; Yamashita, Tatsuya; Mizukoshi, Eishiro; Ikeda, Hiroko; Zen, Yoh; Takamura, Hiroyuki; Wang, Xin Wei; Kaneko, Shuichi　Hepatology　57　4　1484-1497　2013/04/01　
　microRNA-122 Abundance in Hepatocellular Carcinoma and Non-Tumor Liver Tissue from Japanese Patients with Persistent HCV versus HBV Infection　Spaniel, Carolyn; Honda, Masao; Selitsky, Sara R.; Yamane, Daisuke; Shimakami, Tetsuro; Kaneko, Shuichi; Lanford, Robert E.; Lemon, Stanley M.　PLoS ONE　8　10　2013/10/09　
　Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors　Kurosaki, Masayuki;Tanaka, Yasuhito;Nishida, Nao;Sakamoto, Naoya;Enomoto, Nobuyuki;Honda, Masao;Sugiyama, Masaya;Matsuura, Kentaro;Sugauchi, Fuminaka;Asahina, Yasuhiro;Nakagawa, Mina;Watanabe, Mamoru;Sakamoto, Minoru;Maekawa, Shinya;Sakai, Akito;Kaneko, Shuichi;Ito, Kiyoaki;Masaki, Naohiko;Tokunaga, Katsushi;Izumi, Namiki;Mizokami, Masashi　JOURNAL OF HEPATOLOGY　54　3　439-448　2011
　Comparative Analysis of Various Tumor-Associated Antigen-Specific T-Cell Responses in Patients with Hepatocellular Carcinoma　Mizukoshi, Eishiro;Nakamoto, Yasunari;Arai, Kuniaki;Yamashita, Tatsuya;Sakai, Akito;Sakai, Yoshio;Kagaya, Takashi;Yamashita, Taro;Honda, Masao;Kaneko, Shuichi　HEPATOLOGY　53　4　1206-1216　2011
　Differential gene expression profiling in blood from patients with digestive system cancers.　Honda M, Sakai Y, Yamashita T, Yamashita T, Sakai A, Mizukoshi E, Nakamoto Y, Tatsumi I, Miyazaki Y, Tanno H, Kaneko S; Hokuriku Liver Study Group　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　400　1　7-15　2010/09
　The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma　Zeng, Shasha; Yamashita, Taro; Kondo, Mitsumasa; Nio, Kouki; Hayashi, Takehiro; Hara, Yasumasa; Nomura, Yoshimoto; Yoshida, Mariko; Hayashi, Tomoyuki; Oishi, Naoki; Ikeda, Hiroko; Honda, Masao; Kaneko, Shuichi　Journal of Hepatology　60　1　127-134　2014/01/01　
　MICRORNA-27A REGULATES LIPID METABOLISM AND INHIBITS HCV REPLICATION IN HUMAN HEPATOMA CELL LINE　Shirasaki, Takayoshi;Honda, Masao;Tokumaru, Norihiro;Shimakami, Tetsuro;Kawaguchi, Kazunori;Mizuno, Hideki;Shigeyama, Isamu;Yi, MinKyung;Lemon, Stanley;Murakami, Seishi;Kaneko, Shuichi　HEPATOLOGY　54　0　1345A-1345A　2011
　MALNUTRITION IMPAIRS INTERFERON SIGNALING THROUGH MTOR AND FOXO PATHWAYS IN PATIENTS WITH CHRONIC HEPATITIS C　Honda, Masao;Takehana, Kenji;Sakai, Akito;Shirasaki, Takayoshi;Yamashita, Tatsuya;Kawaguchi, Kazunori;Arai, Kuniaki;Shimakami, Tetsuro;Sakai, Yoshio;Yamashita, Taro;Mizukoshi, Eishiro;Nishitani, Shinobu;Tagata, Yusuke;Kaneko, Shuichi　HEPATOLOGY　54　0　843A-844A　2011
　No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations　Sawai, Hiromi; Nishida, Nao; Mbarek, Hamdi; Matsuda, Koichi; Mawatari, Yoriko; Yamaoka, Megumi; Hige, Shuhei; Kang, Jonghon; Abe, Koichi; Mochida, Satoshi; Watanabe, Masaaki; Kurosaki, Masayuki; Asahina, Yasuhiro; Izumi, Namiki; Honda, Masao; Kaneko, Shuichi; Tanaka, Eiji; Matsuura, Kentaro; Itoh, Yoshito; Mita, Eiji; Korenaga, Masaaki; Hino, Keisuke; Murawaki, Yoshikazu; Hiasa, Yoichi; Ide, Tatsuya; Ito, Kiyoaki; Sugiyama, Masaya; Ahn, Sanghoon; Han, Kwanghyub; Park, Junyong; Yuen, Man Fung; Nakamura, Yusuke; Tanaka, Yasuhito; Mizokami, Masashi; Tokunaga, Katsushi　BMC Medical Genetics　13　2012/06/19　
　Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: Possible link to serum anti-endothelial cell antibodies　Sato, Yasunori; Ren, Xiangshan; Harada, Kenichi; Sasaki, Motoko; Morikawa, Hiroyasu; Shiomi, Susumu; Honda, Masao; Kaneko, Shuichi; Nakanuma, Yasuni　Clinical and Experimental Immunology　167　3　532-542　2012/03/01　
　Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.　Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K　FEBS LETTERS　581　10　1983-7　2007/05
　Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma.　Mizukoshi E, Honda M, Arai K, Yamashita T, Nakamoto Y, Kaneko S　JOURNAL OF HEPATOLOGY　49　6　946-54　2008/12
　Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study.　Yamashita T, Arai K, Sakai A, Mizukoshi E, Sakai Y, Kagaya T, Nakamoto Y, Honda M, Wada T, Yokoyama H, Kaneko S　HEPATOLOGY RESEARCH　36　3　167-75　2006/11
　New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia　Nishida, Nao; Sawai, Hiromi; Kashiwase, Koichi; Minami, Mutsuhiko; Sugiyama, Masaya; Seto, Wai-Kay; Yuen, Manfung; Posuwan, Nawarat; Poovorawan, Yong; Ahn, Sanghoon; Han, Kwanghyub; Matsuura, Kentaro; Tanaka, Yasuhito; Kurosaki, Masayuki; Asahina, Yasuhiro; Izumi, Namiki; Kang, Jonghon; Hige, Shuhei; Yamamoto, Tatsuya Ide Kazuhide; Sakaida, Isao; Murawaki, Yoshikazu; Itoh, Yoshito; Tamori, Akihiro; Orito, Etsuro; Hiasa, Yoichi; Honda, Masao; Kaneko, Shuichi; Mita, Eiji; Suzuki, Kazuyuki; Hino, Keisuke; Tanaka, Eiji; Mochida, Satoshi; Watanabe, Masaaki; Eguchi, Yuichiro; Masaki, Naohiko; Murata, Kazumoto; Korenaga, Masaaki; Mawatari, Yoriko; Ohashi, Jun; Kawashima, Minae; Tokunaga, Katsushi; Mizokami, Masashi　PLoS ONE　9　2　e86449　2014/02/10　
　Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.　Misu H, Takamura T, Matsuzawa N, Shimizu A, Ota T, Sakurai M, Ando H, Arai K, Yamashita T, Honda M, Yamashita T, Kaneko S　DIABETOLOGIA　50　2　268-77　2007/02
　Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model.　Seki A, Sakai Y, Komura T, Nasti A, Yoshida K, Higashimoto M, Honda M, Usui S, Takamura M, Takamura T, Ochiya T, Furuichi K, Wada T, Kaneko S.　Hepatology　58　3　1133-42　2013/09/01
　Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes　Takeshita, Yumie; Takamura, Toshinari; Kita, Yuki; Ando, Hitoshi; Ueda, Teruyuki; Kato, Kenichiro; Misu, Hirofumi; Sunagozaka, Hajime; Sakai, Yoshio; Yamashita, Tatsuya; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi　Metabolism: Clinical and Experimental　61　10　1388-1394　2012/10/01　
　Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis　Yamada, Kazutoshi;Mizukoshi, Eishiro;Sunagozaka, Hajime;Arai, Kuniaki;Yamashita, Tatsuya;Takeshita, Yumie;Misu, Hirofumi;Takamura, Toshinari;Kitamura, Seiko;Zen, Yoh;Nakanuma, Yasuni;Honda, Masao;Kaneko, Shuichi　LIVER INTERNATIONAL　35　2　582-590　2015/01/01　
　Identification of blood biomarkers of aging by transcript profiling of whole blood　Nakamura, Seiji; Kawai, Kozo; Takeshita, Yumie; Honda, Masao; Takamura, Toshinari; Kaneko, Shuichi; Matoba, Ryo; Matsubara, Kenichi　Biochemical and Biophysical Research Communications　418　2　313-318　2012/02/10　
　Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma　Sunagozaka, Hajime; Honda, Masao; Yamashita, Taro; Nishino, Ryuhei; Takatori, Hajime; Arai, Kuniaki; Yamashita, Tatsuya; Sakai, Yoshio; Kaneko, Shuichi　International Journal of Cancer　129　7　1576-1585　2011/10/01　
　GENES EXPRESSION OF WHOLE BLOOD CELLS REFLECT THE DISTINCT PATHOPHYSIOLOGICAL FEATURES OF TYPE C CIRRHOSIS AND HEPATOCELLULAR CARCINOMA PATIENTS　Sakai, Yoshio;Honda, Masao;Komura, Takuya;Tatsumi, Isamu;Miyazaki, Yoshitaka;Tanno, Hiroshi;Wada, Takashi;Kaneko, Shuichi　HEPATOLOGY　54　0　784A-784A　2011
　Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.　Matsuzawa N, Takamura T, Kurita S, Misu H, Ota T, Ando H, Yokoyama M, Honda M, Zen Y, Nakanuma Y, Miyamoto K, Kaneko S　HEPATOLOGY　46　5　1392-403　2007/11
　Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma　He, Danning; Liu, Zhiping; Honda, Masao; Kaneko, Shuichi; Chen, Luonan　Journal of Molecular Cell Biology　4　3　140-152　2012/06/01　
　Feasibility and efficacy of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma after sorafenib　Terashima, Takeshi; Yamashita, Tatsuya; Arai, Kuniaki; Sunagozaka, Hajime; Kitahara, Masaaki; Nakagawa, Hidetoshi; Kagaya, Takashi; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi　Hepatology Research　44　12　1179-1185　2014/01/01　
　Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients　Shindo, Hiroko; Maekawa, Shinya; Komase, Kazuki; Sueki, Ryota; Miura, Mika; Kadokura, Makoto; Shindo, Kuniaki; Amemiya, Fumitake; Kitamura, Takatoshi; Nakayama, Yasuhiro; Inoue, Taisuke; Sakamoto, Minoru; Okada, Shunichi; Asahina, Yasuhiro; Izumi, Namiki; Honda, Masao; Kaneko, Shuichi; Enomoto, Nobuyuki　Hepatology International　6　2　482-490　2012/04/01　
　Diagnostic benefits of adrenocortical scintigraphy in hepatic adrenal rest tumor　Ishida, Kosuke; Horii, Rika; Yamashita, Tatsuya; Arai, Kuniaki; Yamashita, Taro; Kagaya, Takashi; Sakai, Yoshio; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi　Journal of Japanese Society of Gastroenterology　111　10　2004-2012　2014/01/01　
　Amplification of Jagged1 copy number in tumor DNA is associated with poor survival from hepatocellular carcinoma　Kawaguchi, Kazunori;Honda, Masao;Yamashita, Taro;Takatori, Hajime;Ueda, Teruyuki;Mizuno, Hideki;Nishikawa, Masashi;Kaneko, Shuichi　HEPATOLOGY　56　0　618A-618A　2012
　Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean　Nishida, Nao; Sawai, Hiromi; Matsuura, Kentaro; Sugiyama, Masaya; Ahn, Sanghoon; Park, Junyong; Hige, Shuhei; Kang, Jonghon; Suzuki, Kazuyuki; Kurosaki, Masayuki; Asahina, Yasuhiro; Mochida, Satoshi; Watanabe, Masaaki; Tanaka, Eiji; Honda, Masao; Kaneko, Shuichi; Orito, Etsuro; Itoh, Yoshito; Mita, Eiji; Tamori, Akihiro; Murawaki, Yoshikazu; Hiasa, Yoichi; Sakaida, Isao; Korenaga, Masaaki; Hino, Keisuke; Ide, Tatsuya; Kawashima, Minae; Mawatari, Yoriko; Sageshima, Megumi; Ogasawara, Yuko; Koike, Asako; Izumi, Namiki; Han, Kwanghyub; Tanaka, Yasuhito; Tokunaga, Katsushi; Mizokami, Masashi　PLoS ONE　7　6　2012/06/21　
　Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes.　Takamura T, Honda M, Sakai Y, Ando H, Shimizu A, Ota T, Sakurai M, Misu H, Kurita S, Matsuzawa-Nagata N, Uchikata M, Nakamura S, Matoba R, Tanino M, Matsubara K, Kaneko S　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　361　2　379-84　2007/09
　Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma.　Ura S, Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Sunakozaka H, Sakai Y, Horimoto K, Kaneko S　HEPATOLOGY　49　4　1098-112　2009/04
　Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population　Nakamura, Minoru; Nishida, Nao; Kawashima, Minae; Aiba, Yoshihiro; Tanaka, Atsushi; Yasunami, Michio; Nakamura, Hitomi; Komori, Atsumasai; Nakamuta, Makoto; Zeniya, Mikio; Hashimoto, Etsuko; Ohira, Hiromasa; Yamamoto, Kazuhide; Onji, Morikazu Morikazu; Kaneko, Shuichi; Honda, Masao; Yamagiwa, Satoshi; Nakao, Kazuhiko; Ichida, Takafumi; Takikawa, Hajime; Seike, Masataka; Umemura, Takeji; Ueno, Yoshiyuki; Sakisaka, Shotaro; Kikuchi, Kentaro; Ebinuma, Hirotoshi; Yamashiki, Noriyo; Tamura, Sumihito; Sugawara, Yasuhiko; Mori, Akira; Yagi, Shintaro; Shirabe, Ken; Taketomi, Akinobu; Arai, Kuniaki; Monoe, Kyoko; Ichikawa, Tatsuki; Taniai, Makiko; Miyake, Yasuhiro; Kumagi, Teru; Abe, Masanori; Yoshizawa, Kaname; Joshita, Satoru; Shimoda, Shinji; Honda, Koichi; Takahashi, Hiroki; Hirano, Katsuji; Takeyama, Yasuaki; Harada, Kenichi; Migita, Kiyoshi; Ito, Masahiro; Yatsuhashi, Hiroshi; Fukushima, Nobuyoshi; Ota, Hajime; Komatsu, Tatsuji; Saoshiro, Takeo; Ishida, Jinya; Kouno, Hirotsugu; Kouno, Hirotaka; Yagura, Michiyasu; Kobayashi, Masakazu; Muro, Toyokichi; Masaki, Naohiko; Hirata, Keiichi; Watanabe, Yukio; Nakamura, Yoko; Shimada, Masaaki; Hirashima, Noboru; Komeda, Toshiki; Sugi, Kazuhiro; Koga, Michiaki; Ario, Keisuke; Takesaki, Eiichi; Maehara, Yoshihiko; Uemoto, Shinji; Kokudo, Norihiro; Tsubouchi, Hirohito; Mizokami, Masashi; Nakanuma, Yasuni; Tokunaga, Katsushi; Ishibashi, Hiromi　American Journal of Human Genetics　91　4　721-728　2012/10/05　
　The Evolution of Diverse Cancer Stem Cells in Human Liver Cancer　Yamashita, Taro;Honda, Masao;Nakamoto, Yasunari;Nio, Kouki;Hara, Yasumasa;Zeng, Sha Sha;Hayashi, Takehiro;Yamashita, Tatsuya;Mizukoshi, Eishiro;Wang, Xin W.;Kaneko, Shuichi　HEPATOLOGY　56　0　443A-443A　2012
　Gene expression profile of primary hepatocytes and the differential innate antiviral response of IFN-alpha and IL28B　Shirasaki, Takayoshi;Honda, Masao;Shimakami, Tetsuro;Okada, Hikari;Lemon, Stanley;Murakami, Seishi;Kaneko, Shuichi　HEPATOLOGY　56　0　705A-705A　2012
　Therapeutic effect of adipose derived mesenchymal stem cell to murine NASH liver cirrhosis inactivating Kupffer/Macrophage and helper T cell　Seki, Akihiro;Sakai, Yoshio;Komura, Takuya;Higashimoto, Mami;Fujinaga, Haruo;Honda, Masao;Wada, Takashi;Takamura, Toshinari;Ochiya, Takahiro;Kaneko, Shuichi　HEPATOLOGY　56　0　1101A-1101A　2012
　Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma　Miyahara, Koji; Nouso, Kazuhiro; Morimoto, Youichi; Takeuchi, Yasuto; Hagihara, Hiroaki; Kuwaki, Kenji; Onishi, Hideki; Ikeda, Fusao; Miyake, Yasuhiro; Nakamura, Shinichiro; Shiraha, Hidenori; Takaki, Akinobu; Honda, Masao; Kaneko, Shuichi; Sato, Takahisa; Sato, Shuichi; Obi, Shuntaro I.; Iwadou, Shouta; Kobayashi, Yoshiyuki; Takaguchi, Kouichi; Kariyama, Kazuya; Takuma, Yoshitaka; Takabatake, Hiroyuki; Yamamoto, K.; Yamamoto, Kazuhide; Morimoro, Yuki; Takuma, Yoshitaka; Takabatake, Hiroyuki; Fujioka, Shinichi; Osawa, Toshiya; Kariyama, Kazuya; Toshimori, Junichi; Kobashi, Haruhiko; Miyatake, Hirokazu; Uematsu, Shuji; Okamoto, Ryoichi; Araki, Yasuyuki; Tatsukawa, Masafumi; Yabushita, Kazuhisa; Shimoe, Toshinari; Sakaguchi, Kohsaku; Sakata, Tatsuro; Kaneyoshi, Toshihiko; Miyashita, Manabi; Makino, Yasuhiro; Moriya, Akio; Ando, Masaharu; Baba, Nobuyuki; Seno, Tomonori; Nagano, Takuya; Matsumoto, Eiji; Takayama, Hiroki　British Journal of Cancer　109　8　2072-2078　2013/10/15　
　The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: A randomised controlled trial　Takeshita, Yumie; Takamura, Toshinari; Honda, Masao; Kita, Yuki; Zen, Yoh; Kato, Kenichiro; Misu, Hirofumi; Ota, Tsuguhito; Nakamura, Mikiko; Yamada, Kazutoshi; Sunagozaka, Hajime; Arai, Kuniaki; Yamashita, Tatsuya; Mizukoshi, Eishiro; Kaneko, Shuichi　Diabetologia　57　5　878-890　2014/01/01　
　Impaired infiltration of immune regulatory cells into liver lobules of chronic hepatitis C patients with interferon-resistant IL28B genotype　Honda, Masao;Sakai, Akito;Shirasaki, Takayoshi;Nakamura, Mikiko;Yamashita, Tatsuya;Arai, Kuniaki;Shimakami, Tetsuro;Sakai, Yoshio;Yamashita, Taro;Mizukoshi, Eishiro;Kaneko, Shuichi　HEPATOLOGY　56　0　708A-708A　2012
　GLYCOGENE EXPRESSION ANALYSIS IN THE LIVER OF CHRONIC HEPATITIS B AND C COMPLICATED WITH HCC ENABLES TO IDENTIFY INFECTION SPECIFIC AND TUMOR SPECIFIC GLYCOGENES USEFUL FOR CLINICAL BIOMARKER　Shigeyama, Isamu;Honda, Masao;Ueda, Teruyuki;Shirasaki, Takayoshi;Yamashita, Taro;Sakai, Yoshio;Kaneko, Shuichi　HEPATOLOGY　54　0　1303A-1303A　2011
　Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis.　Komura T, Mizukoshi E, Kita Y, Sakurai M, Takata Y, Arai K, Yamashita T, Ohta T, Shimizu K, Nakamoto Y, Honda M, Takamura T, Kaneko S　AMERICAN JOURNAL OF GASTROENTEROLOGY　102　9　1939-46　2007/09
　Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C　Tanaka, Yasuhito; Kurosaki, Masayuki; Nishida, Nao; Sugiyama, Masaya; Matsuura, Kentaro; Sakamoto, Naoya; Enomoto, Nobuyuki; Yatsuhashi, Hiroshi; Nishiguchi, Shuhei; Hino, Keisuke; Hige, Shuhei; Itoh, Yoshito; Tanaka, Eiji; Mochida, Satoshi; Honda, Masao; Hiasa, Yoichi; Koike, Asako; Sugauchi, Fuminaka; Kaneko, Shuichi; Izumi, Namiki; Tokunaga, Katsushi; Mizokami, Masashi　Human Molecular Genetics　20　17　3507-3516　2011/09/01　
　MicroRNA expression profiling in serum and liver of patients with chronic hepatitis C　Horii, Rika;Honda, Masao;Sakai, Akito;Nakamura, Mikiko;Kaneko, Shuichi　HEPATOLOGY　56　0　692A-692A　2012
　Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy　Terashima, Takeshi; Yamashita, Tatsuya; Iida, Noriho; Yamashita, Taro; Nakagawa, Hidetoshi; Arai, Kuniaki; Kitamura, Kazuya; Kagaya, Takashi; Sakai, Yoshio; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi　Hepatology Research　2014/01/01　
　Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C. 　Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Kaneko S　HEPATOLOGY　44　5　1122-38　2006/11
　A case of Crohn's disease that showed hepatic portal venous gas and perforation of small intestine at the time of balloon-assisted enteroscopy　Yano, Masaaki; Takatori, Hajime; Kitamura, Kazuya; Kagaya, Takashi; Mizukoshi, Eishiro; Sakai, Akito; Honda, Masao; Tsukada, Tomoya; Fushida, Sachio; Kaneko, Shuichi　Gastroenterological Endoscopy　56　9　3358-3364　2014/01/01　
　Altered hepatic gene expression profiles associated with myocardial ischemia.　Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, Horimoto K, Takamura M.　Circ Cardiovasc Genet.　3　1　68-77　2010/02
　[A case report of S-1 monotherapy for advanced hepatocellular carcinoma].　Yamashita, Tatsuya; Arai, Kuniaki; Terashima, Takeshi; Sunagozaka, Hajime; Shimakami, Tetsuro; Yamashita, Taro; Mizukoshi, Eishiro; Sakai, Akito; Honda, Masao; Kaneko, Shuichi　Gan to kagaku ryoho. Cancer & chemotherapy　39　9　1435-1437　2012/09/01　
　Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+ T-cell suppression.　Higashimoto M, Sakai Y, Takamura M, Usui S, Nasti A, Yoshida K, Seki A, Komura T, Honda M, Wada T, Furuichi K, Ochiya T, Kaneko S.　Eur J Immunol.　43　11　2956-68　2013/11/01
　Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C　Selitsky, Sara R.;Baran-Gale, Jeanette;Honda, Masao;Yamane, Daisuke;Masaki, Takahiro;Fannin, Emily E.;Guerra, Bernadette;Shirasaki, Takayoshi;Shimakami, Tetsuro;Kaneko, Shuichi;Lanford, Robert E.;Lemon, Stanley M.;Sethupathy, Praveen　SCIENTIFIC REPORTS　5　7675　2015/01/01　
　The acyclic retinoid Peretinoin inhibits hepatitis C virus replication and infectious virus release in vitro.　Shimakami, Tetsuro; Honda, Masao; Shirasaki, Takayoshi; Takabatake, Riuta; Liu, Fanwei; Murai, Kazuhisa; Shiomoto, Takayuki; Funaki, Masaya; Yamane, Daisuke; Murakami, Seishi; Lemon, Stanley M.; Kaneko, Shuichi　Scientific reports　4　2014/01/01　
　Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.　Oishi N, Shilagardi K, Nakamoto Y, Honda M, Kaneko S, Murakami S　Cancer Sci.　98　10　1540-8　2007/10
　The development and clinical features of splenic aneurysm associated with liver cirrhosis. 　Sunagozaka H, Tsuji H, Mizukoshi E, Arai K, Kagaya T, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S　Liver Int.　26　3　291-7　2006/04
　Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update　Kaneko, Shuichi; Furuse, Junji; Kudo, Masatoshi; Ikeda, Kenji; Honda, Masao; Nakamoto, Yasunari; Onchi, Morikazu; Shiota, Goshi; Yokosuka, Osamu; Sakaida, Isao; Takehara, Tetsuo; Ueno, Yoshiyuki; Hiroishi, Kazumasa; Nishiguchi, Shuhei; Moriwaki, Hisataka; Yamamoto, Kazuhide; Sata, Michio; Obi, Shuntaro I.; Miyayama, Shiro; Imai, Yukinori　Hepatology Research　42　6　523-542　2012/06/01　
　3 ' SUPPLEMENTARY BASE-PAIR INTERACTIONS OF MIR-122 WITH HEPATITIS C VIRUS RNA CONTRIBUTE TO STABILIZATION OF THE HCV RNA GENOME　Shimakami, Tetsuro;Jangra, Rohit K.;Welsch, Christoph;Yamane, Daisuke;Hensley, Lucinda;Honda, Masao;Kaneko, Shuichi;Lemon, Stanley　HEPATOLOGY　54　0　405A-405A　2011
　Inhibition of Hepatitis C Virus Replication by Acyclic Retinoid　Shimakami, Tetsuro;Honda, Masao;Shirasaki, Takayoshi;Lemon, Stanley;Kaneko, Shuichi　HEPATOLOGY　56　0　713A-714A　2012
　Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection　Yamashita, Taro;Honda, Masao;Kaneko, Shuichi　JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY　26　6　960-964　2011
　Acyclic retinoid and branched chain amino acids improve liver fibrosis and reduce tumorigenesis in mice fed an atherogenic high-fat diet　Takegoshi, Kai;Honda, Masao;Okada, Hikari;Kondo, Mitsumasa;Yamashita, Taro;Matsuzawa, Naoto;Takamura, Toshinari;Tanaka, Takuji;Kaneko, Shuichi　HEPATOLOGY　56　0　770A-770A　2012
　Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development　Okada, Hikari;Honda, Masao;Campbell, Jean S.;Sakai, Yoshio;Yamashita, Taro;Shirasaki, Takayoshi;Tanaka, Takuji;Fausto, Nelson;Kaneko, Shuichi　HEPATOLOGY　56　0　614A-614A　2012
　Efficacy and safety of hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma　Yamashita, Tatsuya;Terashima, Takeshi;Arai, Kuniaki;Sunagozaka, Hajime;Yamashita, Taro;Mizukoshi, Eishiro;Sakai, Akito;Honda, Masao;Kaneko, Shuichi　HEPATOLOGY　56　0　471A-471A　2012
　EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features.　amashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, Jia H, Ye Q, Qin LX, Wauthier E, Reid LM, Minato H, Kaneko S, Tang ZY, Wang XW.　GASTROENTEROLOGY　136　3　1012-24　2009/03
　Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C.　Honda M, Nakamura M, Tateno M, Sakai A, Shimakami T, Shirasaki T, Yamashita T, Arai K, Yamashita T, Sakai Y, Kaneko S　JOURNAL OF HEPATOLOGY　53　5　817-26　2010/11
　A liver-derived secretory protein, selenoprotein P, causes insulin resistance.　Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S　Cell Metab.　12　5　483-95　2010/11
　alpha-FETOPROTEIN-PRODUCING HEPATOMA CELLS HAVE INCREASED JAGGED1 GENE COPY NUMBERS AND THEIR GROWTH CAN BE SUPPRESSED BY GAMMA SECRETASE INHIBITOR　Kawaguchi, Kazunori;Honda, Masao;Yamashita, Taro;Takatori, Hajime;Ueda, Teruyuki;Kanno, Masataka;Nishikawa, Masashi;Kaneko, Shuichi　HEPATOLOGY　54　0　1290A-1290A　2011
　HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2/B1, ASSOCIATED WITH HUMAN TELOMERASE REVERSE TRANSCRIPTASE, IS IDENTIFIED AS A POTENTIAL BIOMARKER FOR HEPATOCELLULAR CARCINOMA BASED ON PROTEOMICS ANALYSIS　Mizuno, Hideki;Honda, Masao;Shirasaki, Takayoshi;Yamashita, Taro;Kaneko, Shuichi　HEPATOLOGY　54　0　1307A-1307A　2011
　IMPAIRED IFN SIGNALING IN CHRONIC HEPATITIS C WITH ADVANCED FIBROSIS STAGE TROUGH TGF-beta SIGNALING PATHWAY　Tokumaru, Norihiro;Honda, Masao;Shirasaki, Takayoshi;Shimakami, Tetsuro;Kawaguchi, Kazunori;Kaneko, Shuichi　HEPATOLOGY　54　0　1331A-1331A　2011
　HCV INFECTIVITY VARIATION AND HVR1 QUASISPECIES SELECTION ARE ASSOCIATED WITH THE DISTRIBUTION OF HCV E1/E2 SYNONYMOUS MUTATIONS　Kawaguchi, Kazunori;Honda, Masao;Shirasaki, Takayoshi;Emerson, Suzanne U.;Purcell, Robert H.;Kaneko, Shuichi　HEPATOLOGY　54　0　1352A-1353A　2011
　Involvement of chromatin remodeling enzyme CHD4 in chemoresistance of EpCAM plus hepatic cancer stem cells　Nio, Kouki;Yamashita, Taro;Honda, Masao;Okada, Hikari;Kaneko, Shuichi　HEPATOLOGY　56　0　278A-278A　2012
　A phase I study of vaccination with human telomerase reverse transcriptase-derived peptide in patients with hepatocellular carcinoma　Mizukoshi, Eishiro;Yamashita, Tatsuya;Arai, Kuniaki;Sunagozaka, Hajime;Yamashita, Taro;Honda, Masao;Kaneko, Shuichi　HEPATOLOGY　56　0　490A-490A　2012
　Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients.　Takamura T, Misu H, Matsuzawa-Nagata N, Sakurai M, Ota T, Shimizu A, Kurita S, Takeshita Y, Ando H, Honda M, Kaneko S　OBESITY RESEARCH　16　12　2601-9　2008/12
　Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy.　Tateno M, Honda M, Kawamura T, Honda H, Kaneko S　JOURNAL OF INFECTIOUS DISEASES　195　2　255-67　2007/01
　Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma.　Minagawa H, Honda M, Miyazaki K, Tabuse Y, Teramoto R, Yamashita T, Nishino R, Takatori H, Ueda T, Kamijo K, Kaneko S　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　366　1　186-92　2008/02
　Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning.　Teramoto R, Minagawa H, Honda M, Miyazaki K, Tabuse Y, Kamijo K, Ueda T, Kaneko S　BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY　1784　5　764-72　2008/05
　Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma.　Nishino R, Honda M, Yamashita T, Takatori H, Minato H, Zen Y, Sasaki M, Takamura H, Horimoto K, Ohta T, Nakanuma Y, Kaneko S　JOURNAL OF HEPATOLOGY　49　2　207-16　2008/08
　Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.　Shimakami T, Honda M, Kusakawa T, Murata T, Shimotohno K, Kaneko S, Murakami S　JOURNAL OF VIROLOGY　80　7　3332-40　2006/04
　ASSOCIATION OF INTERLEUKIN 28B GENOTYPE AND HEPATOCELLULAR CARCINOMA RECURRENCE IN PATIENTS WITH CHRONIC HEPATITIS C　Hodo, Yuji;Honda, Masao;Kaneko, Shuichi　HEPATOLOGY　54　0　1363A-1363A　2011
　ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C.　Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M　HEPATOLOGY RESEARCH　40　11　1063-1071　2010/11
　DISTINCT LIVER CANCER STEM CELLS DEFINED BY EPCAM AND CD90 IN HUMAN HEPATOCELLULAR CARCINOMA　Yamashita, Taro;Honda, Masao;Nakamoto, Yasunari;Mizukoshi, Eishiro;Yamashita, Tatsuya;Arai, Kuniaki;Nio, Kouki;Hara, Yasumasa;Wang, Xin W.;Kaneko, Shuichi　HEPATOLOGY　54　0　449A-449A　2011
　Autoantibody status and histological variables influence biochemical response to treatment and long-term outcomes in Japanese patients with primary biliary cirrhosis　Nakamura, Minoru; Kondo, Hisayoshi; Tanaka, Atsushi; Komori, Atsumasa; Ito, Masahiro; Yamamoto, Kazuhide; Ohira, Hiromasa; Zeniya, Mikio; Hashimoto, Etsuko; Honda, Masao; Kaneko, Shuichi; Ueno, Yoshiyuki; Kikuchi, Kentaro; Shimoda, Shinji; Harada, Kenichi; Arai, Kuniaki; Miyake, Yasuhiro; Abe, Masanori; Taniai, Makiko; Saibara, Toshiji; Sakisaka, Shotaro; Takikawa, Hajime; Onji, Morikazu Morikazu; Tsubouchi, Hirohito; Nakanuma, Yasuni; Ishibashi, Hiromi　Hepatology Research　45　8　846-55　2015/01/01　
　Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.　Matsuzawa-Nagata N, Takamura T, Ando H, Nakamura S, Kurita S, Misu H, Ota T, Yokoyama M, Honda M, Miyamoto K, Kaneko S　METABOLISM-CLINICAL AND EXPERIMENTAL　57　8　1071-7　2008/08
　CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes.　Komura T, Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S　DIABETES　59　3　634-43　2010/03
　Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma.　Hodo Y, Hashimoto S, Honda M, Yamashita T, Suzuki Y, Sugano S, Kaneko S, Matsushima K　GENOMICS　95　4　217-23　2010/04
　La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication.　Shirasaki T, Honda M, Mizuno H, Shimakami T, Okada H, Sakai Y, Murakami S, Wakita T, Kaneko S　JOURNAL OF INFECTIOUS DISEASES　202　1　75-85　2010/07
　Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients.　Sakai Y, Honda M, Fujinaga H, Tatsumi I, Mizukoshi E, Nakamoto Y, Kaneko S　CANCER RESEARCH　68　24　10267-79　2008/12
　Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma.　Yamashita T, Honda M, Takatori H, Nishino R, Minato H, Takamura H, Ohta T, Kaneko S.　JOURNAL OF HEPATOLOGY　50　1　100-10　2009/01
　dUTP pyrophosphatase expression correlates with a poor prognosis in hepatocellular carcinoma.　Takatori H, Yamashita T, Honda M, Nishino R, Arai K, Yamashita T, Takamura H, Ohta T, Zen Y, Kaneko S　Liver Int.　30　3　438-46　2010/03
　POSITIVE ANTI-GP210 ANTIBODIES IS A SIGNIFICANT RISK FACTOR FOR BILE DUCT LOSS, HEPATITIS AND POOR BIOCHEMICAL RESPONSE TO URSODEOXYCHOLIC ACID TREATMENT THAT LEAD TO MORE SEVERE PROGRESSION IN JAPANESE PATIENTS WITH PRIMARY BILIARY CIRRHOSIS　Nakamura, Minoru;Ito, Masahiro;Kondo, Hisayoshi;Yamamoto, Kazuhide;Ohira, Hiromasa;Zeniya, Mikio;Tanaka, Atsushi;Hashimoto, Etsuko;Honda, Masao;Kaneko, Shuichi;Ueno, Yoshiyuki;Kikuchi, Kentaro;Shimoda, Shinji;Komori, Atsumasa;Harada, Kenichi;Sakisaka, Shotaro;Takikawa, Hajime;Onji, Morikazu;Onishi, Saburo;Tsubouchi, Hirohito;Nakanuma, Yasuni;Ishibashi, Hiromi　HEPATOLOGY　54　0　1208A-1209A　2011
　Expression of chondroitin-glucuronate C5-epimerase and cellular immune responses in patients with hepatocellular carcinoma　Mizukoshi, Eishiro; Fushimi, Kazumi; Arai, Kuniaki; Yamashita, Tatsuya; Honda, Masao; Kaneko, Shuichi　Liver International　32　10　1516-1526　2012/11/01　
　A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma　Okusaka, Takuji; Kasugai, Hiroshi; Ishii, Hiroshi; Kudo, Masatoshi; Sata, Michio; Tanaka, Katsuaki; Shioyama, Yasukazu; Chayama, Kazuaki; Kumada, Hiromitsu; Yoshikawa, Masaharu; Seki, Toshihito; Saito, Hidetsugu; Hayashi, Naoaki; Shiratori, Keiko; Okita, Kiwamu; Sakaida, Isao; Honda, Masao; Kusumoto, Yukio; Tsutsumi, Takuya; Sakata, Kenji　Investigational New Drugs　30　5　2015-2025　2012/10/01

Conference Presentations

Surrogacy of time to progression for overall survival in advanced hepatocellular carcinoma treated with systemic therapy: A systematic review and eta-analysis of randomized controlled trials.(conference：ASCO-GI 2018)(2018/01/19)
NASH患者における肝線維化と血清AKR1B10との関連(2018/04/19)
Characteristics and Functional Regulation of Dendritic Cells in Hepatitis B Patients(2018/11/09)
Immune response to tumor-associated antigens and immune vell profiles in NASH-related hepatocellular carcinoma(2018/11/12)
Adipose tissue derived stromal/stem cells alleviated hepatic fibrosis development induced by IL17-mediated stellate cell activation in NASH mice.(2018/11/11)

show all

Levocarnitine improves Liver Histology and the Development of Hepatocellular Carcinoma in the　Atherogenic High-Fat Diet Nash-HCC Mouse Model(2018/11/11)
Inactivation of transcriptional repressor capicua confers chemoresistance to sorafenib in hepatocellular carcinoma(2018/11/12)
Mint3 is a novel molecular target expressed in well-differentiated AFP-negative HCC for prevention of cancer progression.(2018/11/10)
A Liver-Derived Secretory Protein, LECT2, Enhances the Innate Immune Response and Suppresses RIG-I Mediated Virus Infection(2018/11/10)
A liver-derived secretory protein, LECT2, restores the impaired plasmacytoid dendritic cells function by HBV and protects hepatocytes against HBV infection(conference：2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses)(2018/10/05)
Dendritic cell functions and characteristic gene expression profiles in hepatitis B virus-infected patients(2017/10/31)
Identification of novel HLA-A24-restricted endogenous CTL epitopes derived from HBV genotype C(conference：AASLD2017)(2017/10/22)
Inhibitory effect of acyclic retinoid on hepatitis B virus replication(conference：AASLD2017)(2017/10/22)
A liver-derived secretory protein, LECT2, activates plasmacytoid dendritic cells and protects hepatocytes from HBV infection(conference：AASLD2017)(2017/10/22)
Promoted liver fibrosis and malignant phenotype in HCV/PDGF-C transgenic mouse are accompanied by abnormal expression of the glycolysis-related gene pyruvate kinase M(conference：AASLD2017)(2017/10/23)
Immunomodulation of aggressive liver cancer by EpCAM+ cancer stem cells thorough the activation of CCL20-CCR6 axis(conference：AASLD2017)(2017/10/23)
The utility of the serum C16:1n7/C16:0 ratio as a diagnostic marker of non-alcoholic steatohepatitis(conference：AASLD2017)(2017/10/23)
Notch signaling inhibition is associated with degradation of intrahepatic HBV by ITCH in an ubiquitin-dependent manner(conference：AASLD2017)(2017/10/22)
Nucleos(t)ide analogues and interferon affect intranuclear HBV genome in vitro via Notch signaling modification,independent of the ubiquitin-proteasome system(conference：AASLD2017)(2017/10/22)
IFN-λ3 induces dendritic cell maturation independent of type I IFN(conference：AASLD2017)(2017/10/21)
mRNA for selenoprotein P, a hepatokine, binds RIG-I protein and inhibits the RIG-I-mediated type I interferon response(2017/10/21)
Regulation of Hepatitis C Virus Infection by Long Non-Coding RNA(2017/10/21)
MicroRNA-10a is associated with the impaired liver functions in patients with advanced stage of chronic hepatitis C(2017/10/21)
Osteopontin regulates IFN signaling and HCV replication in cancer stem cells(2017/10/21)
Serum Cytokine Profiles Predict Survival Benefits in Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib: a Retrospective Cohort Study(conference：AASLD2017)(2017/10/20)
Genome-wide methylation analysis identified a new intrahepatic angiogenesis marker associated with induction of tumorigenesis after successful eradication of HCV(2017/10/21)
Unexpected Enhancement of Replication Capacity by Simeprevir for Simeprevir-Resistant Variants in Genotype 1a Hepatitis C Virus(2017/10/21)
　(2017/06/09)
Strategy for the Treatment for Chronic Hepatitis C Patients in Japan(conference：2nd international symposium on viral Hepatitis)(2015/06/23)
HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma.(conference：AASLD2015)(2015/11/16)
HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma(conference：International Meeting on Molecular Biology of Hepatitis B Viruses　2015)(2015/10/05)
動脈硬化高脂肪食マウスモデルにおける非環式レチノイドの脂肪化・肝発癌抑制効果の検討(2015/12/03)
Treatment of HCV-infected patients in Japan and an Experimental Model of HCV Infection(2014/12/10)
Impaired IFN signaling in chronic hepatitis C patients with advanced fibrosis via the TGF-β signaling pathway(2014/09/07)
C型慢性肝炎IL28Bマイナー遺伝子多型例における肝内ISG高値と治療抵抗性の機序(2013/06/06)
Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes. パラレルセッション（口演）(conference：AASLD2013)(2013/11/05)
Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes.(conference：HCV2013)(2013/10/08)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

○IFNL4の臨床応用
○HBV

Grant-in-Aid for Scientific Research

○「Nucleotide analogue製剤のサイトカイン誘導を利用してB型肝炎のドラックフリーを目指す治療法の開発および創薬に関する研究」(2018-2020)　
○「NAFLD/NASH肝組織リン酸化活性プロファイリングと新規治療標的分子の同定」(2018-2020)　
○「DOCK12ノックダウンによりcccDNA排除の新規抗HBV治療応用への基礎研究」(2018-2020)　
○「肝線維化に伴うリモデリングを正常化する新規治療法の開発」(2017-2019)　
○「C型肝炎ウイルス排除後の病態、生命予後、QOLに関する包括的研究」(2017-2019)　
○「肝硬変における炎症細胞社会の解明」(2017-2021)　
○「C型肝炎における慢性肝炎から発がんに至る病態の解明と制御に関する研究」(2016-2018)　
○「C型肝炎の新たな治療関連因子及び治癒後の病態進展・改善に関連する宿主因子等の同定を目指したゲノムワイド研究」(2016-2018)　
○「IFNλ4 の機能的役割の解明及び新規診断法・治療法の開発」(2016-2018)　
○「Ｃ型肝炎における慢性肝炎から発がんに至る病態の解明と制御に関する研究」(2016-2018)　
○「包括的１細胞遺伝子発現解析を用いたB型肝炎ウイルス感染機構の解明」(2016-)　
○「肝炎ウイルス治療後の肝発癌機序とバイオマーカーの同定に関する研究」(2015-2017)　
○「内分泌器官としての肝臓病学の確立」(2014-2018)　
○「ゲノム網羅的解析によるＢ型肝炎ウイルス感染の病態関連遺伝子の同定と新規診断法の開発」(2014-2016)　
○「肝炎ウイルス複製を支持する新規肝癌由来培養細胞の樹立」(2014-2015)　
○「Ｃ型肝炎の新規診断法や新規治療法を開発するためのゲノムワイド関連解析の手法を用いた宿主因子の解析に関する研究」(2013-2015)　
○「Ｃ型慢性肝炎治療成績の向上と肝発癌阻止を目指した分子基盤の確立」(2012-2014)　
○「過栄養状態の肝臓が産生するタンパクと生活習慣病の関連」(2011-2013)　
○「ウイルス性肝炎に対する応答性を規定する宿主因子も含めた情報のデータベース構築・治療応用に関する研究」(2010-2012)　
○「肝がんの新規治療法に関する研究」(2009-2011)　
○「C型慢性肝炎インターフェロン療法の応答・不応答に関わる宿主遺伝子の探索」(2009-2011)　
○「肝炎ウイルスの培養系を用いた新規肝炎治療法の開発」(2007-2009)　
○「末梢血単核球の発現プロファイルと肝病態」(2007-2008)　
○「テーラーメイド治療を目指した肝炎ウイルスデータベース構築に関する研究」(2007-2009)　
○「C型肝炎ウイルス増殖に関わる宿主因子の同定とその肝病態における役割」(2005-2006)　
○「C型肝炎ウイルス増殖に関わる宿主因子の同定」(2002-2003)　
○「Ｃ型肝炎ウイルスの蛋白翻訳開始機構に関する検討」(1998-1999)　
○「インターフェロンによるＣ型肝炎ウイルス蛋白翻訳抑制機構の解明」(2000-2001)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Microbiology Genetics(2018)
○Introduction of Clinical Medicine(2018)
○Introduction of Clinical Medicine(2018)
○Research Project(2018)
○Lecture and Practice of Virology(2018)
○Pathogenic Microbiology 2(2018)
○Pathophysiology 1(2018)
○Introduction to Practical Medicine(2018)
○Experimental Course of Clinical Physiology II(2018)
○Laboratory of Serology and Immunology(2018)
○Presentation and Debate (Freshman Seminar II)(2018)
○Presentation and Debate (Freshman Seminar II)(2017)
○Experimental Course of Clinical Physiology(2017)
○Introduction of Clinical Medicine(2017)
○Introduction of Clinical Medicine(2017)
○Pathogenic Microbiology 2(2017)
○Lecture and Practice of Virology(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Introduction to Practical Medicine(2017)
○Microbiology Genetics(2017)
○Introduction to Practical Medicine(2017)
○Laboratory of Serology and Immunology(2017)

Classes (Graduate Schools)

○Molecular Biology of Tumor: Lecture(2018)
○Molecular Biology of Tumor: Seminar(2018)
○Laboratory Oncology: Lecture(2018)
○Laboratory Oncology: Seminar(2018)
○Laboratory Oncology: Research(2018)
○Advanced Laboratory Oncology: Research(2018)
○Introduction to Medicine(2018)
○An Introduction to Medical Laboratory Sciences:Lec(2018)
○Fostering the independence of researchers(2018)
○omics(2017)
○Molecular Biology of Tumor: Lecture(2017)
○An Introduction to Medical Laboratory Sciences:Lec(2017)
○Molecular Biology of Tumor: Seminar(2017)
○Laboratory Oncology: Research(2017)
○Introduction to Medicine(2017)
○Laboratory Oncology: Lecture(2017)
○Laboratory Oncology: Seminar(2017)
○Advanced Laboratory Oncology: Research(2017)
○Fostering the independence of researchers(2017)

Professor　HONDA, Masao

Faculty, Affiliation

College and School Educational Field

Laboratory

Academic Background

Career

Year & Month of Birth

Academic Society

Award

Specialities

Speciality Keywords

Research Themes

Viral Hepatitis

NASH

Hepatokine

Hepatic fibrosis

Molecular biology of HCC

Tumor immunity

Books

Papers

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

Professor HONDA, Masao

Faculty, Affiliation

College and School Educational Field

Laboratory

Academic Background

Career

Year & Month of Birth

Academic Society

Award

Specialities

Speciality Keywords

Research Themes

Viral Hepatitis

NASH

Hepatokine

Hepatic fibrosis

Molecular biology of HCC

Tumor immunity

Books

Papers

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

Professor　HONDA, Masao