Assistant Professor TADOKORO Yuko
Faculty, Affiliation
Cancer Research Institute
College and School Educational Field
Division of Medicine, Graduate School of Medical Science
Laboratory
TEL:076-265-2727 FAX:076-234-4508
Academic Background
【Academic background(Doctoral/Master's Degree)】
Osaka University
【Degree】
Master (Pharmacology), Ph.D (Pharmacology)
Career
Research Fellow of the Japan Society for the Promotion of Science
Institute of Medical Science, University of Tokyo, Researcher of Industry-Academia-Government Collaboration
University of Tokyo, Researcher of Industry-Academia-Government Collaboration
Year & Month of Birth
1976/01
Academic Society
The molecular biology society of Japan
Award
Specialities
Speciality Keywords
stem cell
Research Themes
Study of tissue specific stem cell systems
Study of tissue specific stem cell systems
Books
- Stem Cell Populations in Hair Follicle and Their Niches 64 806 157-169 2009/06
Papers
- Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway Yuko Tadokoro, Kentaro Yomogida, Hiroshi Ohta, Akira Tohda, Yoshitake Nishimune MECHANISMS OF DEVELOPMENT 113 1 29-39 2002
- Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis Yuko Kato, Atsushi Iwama, Yuko Tadokoro, Kazuya Shimoda, Mayu Minoguchi, Shizuo Akira, Minoru Tanaka, Atsushi Miyajima, Toshio Kitamura, and Hiromitsu Nakauchi JOURNAL OF EXPERIMENTAL MEDICINE 202 1 169-179 2005
- De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells Yuko Tadokoro, Hideo Ema, Masaki Okano, En Li, Hiromitsu Nakauchi JOURNAL OF EXPERIMENTAL MEDICINE 204 4 715-722 2007/04
- Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction Jun Seita, Hideo Ema, Jun Ooehara, Satoshi Yamazaki, Yuko Tadokoro, Akiko Yamasaki, Koji Eto, Satoshi Takaki, Kiyoshi Takatsu, Hiromitsu Nakauchi PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME 104 7 2349-2354 2007
- In vivo and in vitro constant expression of GATA-4 in mouse postnatal Sertoli cells T. Imai, Y. Kawai, Y. Tadokoro, M. Yamamoto, Y. Nishimune, K. Yomogida MOLECULAR AND CELLULAR ENDOCRINOLOGY 214 1 107-115 2004
- Dramatic expansion of germinal stem cells by ectopically expressed human glial cell line-derived neurotrophic factor in mouse Sertoli cells Kentaro Yomogida, Yo Yagura, Yuko Tadokoro, Yoshitake Nishimune BIOLOGY OF REPRODUCTION 69 4 1303-1307 2003
- Novel actin-like proteins T-ACTIN 1 and T-ACTIN 2 are differentially expressed in the cytoplasm and nucleus of mouse haploid germ cells Hiromitsu Tanaka, Naoko Iguchi, Carlos Egydio de Carvalho, Yuko Tadokoro, Kentaro Yomogida, Yoshitake Nishimune BIOLOGY OF REPRODUCTION 69 2 475-482 2003
- Two mouse piwi-related genes: miwi and mili Satomi Kuramochi-Miyagawa, Tohru Kimura, Kentaro Yomogida, Asato Kuroiwa, Yuko Tadokoro, Yukiko Fujita, Masatake Sato, Yoichi Matsuda, Toru Nakano MECHANISMS OF DEVELOPMENT 108 1 121-133 2001
- Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd ) mice Akira Tohda, Kiyomi Matsumiya, Yuko Tadokoro, Kentaro Yomogida, Yasushi Miyagawa, Kayoko Dohmae, Akihiko Okuyama, Yoshitake Nishimune BIOLOGY OF REPRODUCTION 65 2 532-537 2001
- Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation HIROSHI OHTA, KENTARO YOMOGIDA, YUKO TADOKORO, AKIRA TOHDA, KAYOKO DOHMAE and YOSHITAKE NISHIMUNE INTERNATIONAL JOURNAL OF ANDROLOGY 24 1 15-23 2001
- Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis Shuhei Yamada, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara GLYCOBIOLOGY 19 5 488-498 2009/05
- Molecular pathology of tumor-initiating cells: Lessons from Philadelphia chromosome-positive leukemia PATHOLOGY INTERNATIONAL 61 501 2011/09
- NKX2.2 suppresses self-renewal of glioma-initiating cells CANCER RESEARCH 71 1135 2011/02
- Hair follicle stem cells provide a functional niche for melanocyte stem cells Cell Stem Cell 8 177 2011/02
Conference Presentations
Others
- Characterization of Histone H2A.X Expression in Testis and Specific Labeling of Germ Cells at the Commitment Stage of Meiosis with Histone H2A.X Promoter-Enhanced Green Fluorescent Protein Transgene Yuko Tadokoro, Kentaro Yomogida, Yo Yagura, Shuichi Yamada, Masaru Okabe, and Yoshitake Nishimune 69 4 1325-1329 2003
- Adult mouse hematopoietic stem cells: purification and single-cell assays Hideo Ema, Yohei Morita, Satoshi Yamazaki, Azusa Matsubara, Jun Seita, Yuko Tadokoro, Hiroyoshi Kondo, Hina Takano, Hiromitsu Nakauchi 1 6 2979-2987 2006
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「色素幹細胞におけるSpred-1の機能と組織幹細胞制御機構の共通分子基盤の解明」(2007-2008)
○「色素幹細胞の質的変化に着目した白髪の発症機序の解明」(2007-)
○「Spred-1の機能に着目した造血幹細胞及び白血病幹細胞ニッチの解析」(2009-)
○「細胞内ATP調節による造血幹細胞制御機構の解明」(2011-2012)
○「Spred-1の機能に着目した造血幹細胞及び白血病幹細胞ニッチの解析」(2009-2010)