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Researcher Information

last modified：2024/10/10

Assistant Professor　NAGAYA Satomi

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Faculty, Affiliation

Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Health Sciences, Graduate School of Medical Science
Department of Laboratory Sciences，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Academic Background

Career

Asanogawa General Hospital(2010/04/01-2020/03/31)
Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University(2020/04/01-)

Year & Month of Birth

Academic Society






Award


Specialities

Laboratory medicine、Hematology

Speciality Keywords

laboratory hematology, thrombosis and hemostasis, inherited thrombophilia

Research Themes

Molecular analysis of thrombus formation mechanism by abnormal prothrombin with thrombomodulin binding disorder

Pathophysiology of inherited thrombophilia

Clarification of factors affecting protein S activity

Books

Papers

  • 　Identification of two de novo variants causing inherited antithrombin deficiency by quantitative analysis of variant alleles.　Nagaya S & Togahi T, Meguro-Horike M, Matsumoto H, Imai Y, Yamaguchi K, Fujii Y, Moriya H, Kikuchi Y, Yasuda I, Horike SI, Morishita E.　Thromb Res　233　37-40　2023/11/20
  • 　Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics.　Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Horike SI, Kawasaki H, Morishita E.　Thromb Res　230　18-26　2023/10/01
  • 　Protein S deficiency caused by cryptic splicing due to the novel intron variant c.346+5G>C in PROS1.　Nagaya S & Togashi T & Akiyama M, Imai Y, Matsumoto Haruto, Moriya H, Meguro-Horike M, Yasuda I, Kikuchi Y, Kuwajima Y, Horike SI, Watanabe A, Morishita E　Thromb Res　229　26-30　2023/06/28
  • 　Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.　Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Ohmori K, Makita Y, Sato E, Yujiri T, Nagamori Y, Horike SI, Watanabe A, Morishita E.　117　4　523-529　2022/12/16
  • 　A case of venous thromboembolism caused by protein C deficiency due to a novel gene mutation　Noiri J, Matsuzoe H, Nagaya S, Nishio R, Matsumoto D, Takaishi H, Morishita E.　J Cardiol Cases　26　5　360-363　2022/08/12

show all

  • 　First report of inherited protein S deficiency caused by paternal PROS1 mosaicism.　Nagaya S & Maruyama K, Watanabe A, Meguro-Horike M, Imai Y, Hiroshima Y, Horike SI, Kokame K, Morishita E.　Haematologica　107　1　330-333　2021/10/14
  • 　Effect on Plasma Protein S Activity in Patients Receiving the Factor Xa Inhibitors.　Nagaya S & Terakami T, Hayashi K, Furusho H, Fujino N, Kato T, Asakura H, Morishita E.　J Atherosclerosis Thromb　28　2021/07/30
  • 　A case of treatment with dabigatran for cerebral venous thrombosis caused by hereditary protein C deficiency.　Fukushima T, Shimomura Y, Nagaya S, Morishita E, Kawakami O. 　Cureus　13　6　e15473　2021/06/06
  • 　Protein C Gene Mutation in an Older Adult Patient with Clostridium perfringens Septicemia-Related Visceral Vein Thrombosis.　Kanosue K,Nagaya S, Morishita E, Yamanishi M, Imashuku S.　TH Open　5　2　171-173　2021/05/26
  • 　Evaluation of Optimal Sample Processing Conditions for Accurate Measurement of Protein S Activity.　Nagaya S, Araiso Y, Yamaguchi K, Omote Y, Matsui A, Asakura H, Morishita E.　Ann Clin Lab Sci　51　2　206-212　2021/03/31
  • 　Molecular genetic analysis of inherited protein C deficiency caused by the novel large deletion across two exons of PROC.　Togashi T, Meguro-Horike M, Nagaya S, Sugihara S, Ichinose T, Araiso Y, Yamaguchi K, Mori K, Imai Y, Kuzasa K, Horike SI, Asakura H, Morishita E.　Thromb Res　188　115-118　2020/04/01
  • 　Genetic analysis of a compound heterozygous patient with congenital factor X deficiency and regular replacement therapy with a prothrombin complex concentrate.　Togashi T, Nagaya S, Nagasawa M, Meguro-Horike M, Nogami K, Imai Y, Kuzasa K, Sekiya A, Horike SI, Asakura H, Morishita E.　Int J Hematol　111　1　51-56　2020/01/01
  • 　Congenital coagulation factor X deficiency: Genetic analysis of five patients and functional characterization of mutant factor X proteins.　Nagaya S, Akiyama M, Murakami M, Sekiya A, Asakura H, Morishita E.　Haemophilia　24　5　774-785　2018/09/01
  • 　A case of factor X (FX) deficiency due to novel mutation V196M, FX Hofu.　Shinohara K, Adachi M, Matsui K, Matsuda K, Nagaya S, Morishita E.　Int J Hematol　87　3　256-259　2008/04/01

Conference Presentations

Others

  • 　The measurements of anti-cardiolipin IgG/IgM antibody and anti-β2GP I IgG/IgM antibody　Satomi Nagaya, Eriko Morishita　67　3　146　2021/03/01
  • 　Changes in coagulation and fibrinolytic factors and molecular markers during pregnancy　Satomi Nagaya, Eriko Morishita　Kensa to Gizyutsu　50　1　20　2022/01/01

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「異常トロンビンのトロンボモジュリンまたはPAR-1を介した血栓形成メカニズムの解明」(2024-2025)　
○「Analysis of the mechanism of thrombogenesis mediated by thrombomodulin or PAR-1 of abnormal thrombin」(2022-2023)　
○Research Activity start-up「異常プロトロンビンのトロンボモジュリン抵抗性による血栓症発症機序の解明」(2020-2021)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Clinial Practice of Hematology and Blood Transfusion(2023)
○Clinial Practice of Clinical Physiology(2023)
○Experimental Course of Clinical Physiology II(2023)
○Hematology(2023)
○Laboratory Information Management(2023)
○Hematology(2023)
○Clinial Practice of Clinical Physiology(2023)
○Experimental Course of Clinical Physiology II(2023)
○Laboratory Information Management(2023)
○Clinial Practice of Hematology and Blood Transfusion(2023)
○Practice in Laboratory Hematology(2023)
○Presentation and Debate(2023)
○Practice in Laboratory Hematology(2023)
○Physiology(2023)
○Academic Skill(2023)
○Physiology(2023)
○Introduction to Region-studies(2023)
○Clinial Practice of Clinical Physiology(2022)
○Clinial Practice of Hematology and Blood Transfusion(2022)
○Laboratory Hematology(2022)
○Experimental Course of Clinical Physiology II(2022)
○Laboratory Information Management(2022)
○Laboratory Hematology(2022)
○Laboratory Information Management(2022)
○Clinial Practice of Clinical Physiology(2022)
○Experimental Course of Clinical Physiology II(2022)
○Clinial Practice of Hematology and Blood Transfusion(2022)
○Clinical Physiology 2(2022)
○Experimental Course in Physiology(2022)
○Practice in Laboratory Hematology(2022)
○Clinical Physiology 2(2022)
○Experimental Course in Physiology(2022)
○Practice in Laboratory Hematology(2022)
○Human Physiology(2022)
○Human Physiology(2022)
○Experimental Course in Physiology(2022)
○Practice in Laboratory Hematology(2022)
○Human Physiology(2022)
○Public Health(2021)
○Human Physiology(2021)
○Laboratory Hematology(2021)
○Clinial Practice of Clinical Physiology(2021)
○Clinical Physiology II(2021)
○Clinial Practice of Hematology and Blood Transfusion(2021)
○Experimental Course of Clinical Physiology II(2021)
○Practice in Laboratory Hematology(2021)
○Clinical Physiology I(2020)
○Laboratory Hematology(2020)
○Clinical Physiology II(2020)
○Experimental Course of Clinical Physiology II(2020)
○Practice in Laboratory Hematology(2020)
○Experimental Course in Physiology(2020)
○Human Physiology(2020)
○Public Health(2020)
○Clinial Practice of Clinical Physiology(2020)
○Clinial Practice of Hematology and Blood Transfusion(2020)

Classes (Graduate Schools)

○Clinical Immunohematology: Seminar(2023)
○Clinical Immunohematology: Seminar(2023)
○Clinical Immunohematology: Seminar(2023)
○Clinical Immunohematology: Seminar(2023)
○Laboratory Rotation Ⅱ(2023)
○Laboratory Rotation Ｉ(2023)
○Clinical Immunohematology: Lecture(2023)
○Clinical Immunohematology: Lecture(2023)
○An Introduction to Medical Laboratory Sciences:Lec(2023)
○An Introduction to Medical Laboratory Sciences:Lec(2023)
○Laboratory Rotation Ⅱ(2023)
○Laboratory Rotation Ｉ(2023)
○Clinical Immunohematology: Lecture(2023)
○Clinical Immunohematology: Lecture(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory Rotation I(2023)
○Laboratory Rotation I(2023)
○Clinical Immunohematology: Seminar(2022)
○Clinical Immunohematology: Seminar(2022)
○An Introduction to Medical Laboratory Sciences:Lec(2022)
○Clinical Immunohematology: Lecture(2022)
○Clinical Immunohematology: Lecture(2022)

International Project

International Students

Lecture themes

Others (Social Activities)

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