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Researcher Information

last modified：2024/11/23

Assistant Professor　KOJO, Satoshi

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Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences

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Laboratory

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  • 　Suppression of IgE antibody responses by NKT cells-mechanisms of NKT cell-mediated regulatory function　Satoshi Kojo,Michishige Harada,Ken-ichiro Seino,Masaru Taniguchi　International Congress Series　1285　179　2005/11
  • 　Induction of regulatory properties in dendritic cells by V alpha 14 NKT cells　S Kojo,K Seino,M Harada,H Watarai,H Wakao,T Uchida,T Nakayama,M Taniguchi　JOURNAL OF IMMUNOLOGY　175　6　3648　2005/09
  • 　Expression of tristetraprolin (G0S24) mRNA, a regulator of tumor necrosis factor-alpha production, in synovial tissues of patients with rheumatoid arthritis　A Tsutsumi,E Suzuki,Y Adachi,H Murata,D Goto,S Kojo,Matsumoto, I,L Zhong,H Nakamura,T Sumida　JOURNAL OF RHEUMATOLOGY　31　6　1044　2004/06
  • 　Down-regulation of the invariant V alpha 14 antigen receptor in NKT cells upon activation　M Harada,K Seino,H Wakao,S Sakata,Y Ishizuka,T Ito,S Kojo,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　16　2　241　2004/02
  • 　Impaired IFN-gamma production of V(alpha)24NKT cells in non-remitting sarcoidosis　S Kobayashi,Y Kaneko,K Seino,Y Yamada,S Motohashi,J Koike,K Sugaya,T Kuriyama,S Asano,T Tsuda,H Wakao,M Harada,S Kojo,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　16　2　215　2004/02

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  • 　Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch　E Kondo,H Wakao,H Koseki,T Takemori,S Kojo,M Harada,M Takahashi,S Sakata,C Shimizu,T Ito,T Nakayama,M Taniguchi　INTERNATIONAL IMMUNOLOGY　15　3　393　2003/03
  • 　Identification of Th2-type suppressor T cells among in vivo expanded ocular T cells in mice with experimental autoimmune uveoretinitis　H Keino,M Takeuchi,J Suzuki,S Kojo,J Sakai,K Nishioka,T Sumida,M Usui　CLINICAL AND EXPERIMENTAL IMMUNOLOGY　124　1　1　2001/04
  • 　Analysis of T cell receptor V-beta gene expression and clonality in bronchoalveolar fluid lymphocytes from a patient with chronic eosinophilic pneumonitis　N Shimizudani,H Murata,S Kojo,Y Adachi,H Keino,F Tsuchida,M Sumida,M Kawamata,T Sumida,T Matsuoka　LUNG　179　1　31　2001/01
  • 　Regulatory function of NKT cells in the protection of autoimmune disease development　Taniguchi, Masaru,Nakagawa, Ryusuke,Kojo,Satoshi a,Watarai, Hiroshi　Journal of Neuroimmunology　178　14　2006/09
  • 　G0S24, a gene that regulates TNFa production,is highly expressed in synovial tissue from patients with rheumatoid arthritis.　Tsutsumi, A,Adachi, Y,Murata, H,Kojo, S,Shibuya, K,Nakamura, H,and,Sumida T,住田, 孝之　J. Rheumatol.　31　6　1044-9　2004/01
  • 　Alternative splicing forms of the human CD1D gene in mononuclear cells　S Kojo,Y Adachi,A Tsutsumi,T Sumida　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　276　1　107　2000/09
  • 　The regulatory role of V alpha 14 NKT cells in innate and acquired immune response　Taniguchi, M.,Harada, M.,Kojo, S.,Nakayama, T.,Wakao, H.　Annual Review of Immunology　21　483　2003　
  • 　Conserved CDR 3 region of T cell receptor BV gene in lymphocytes from bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis　N Shimizudani,H Murata,H Keino,S Kojo,H Nakamura,Y Morishima,T Sakamoto,M Ohtsuka,K Sekisawa,M Sumida,T Sumida,T Matsuoka　CLINICAL AND EXPERIMENTAL IMMUNOLOGY　129　1　140　2002/07
  • 　Cutting edge: Critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance　XF Jiang,T Shimaoka,S Kojo,M Harada,H Watarai,H Wakao,N Ohkohchi,S Yonehara,M Taniguchi,K Seino　JOURNAL OF IMMUNOLOGY　175　4　2051　2005/08
  • 　Low expression of soluble CD1d in patients with rheumatoid arthritis.　Goto, D.,Kojo, S.,Matsumoto, I.,Ito, S.,Tsutsumi, A.,Sumida, T.　Arthritis and Rheumatism　50　9　S528　2004/01
  • 　The importance of CD25(+)CD4(+) regulatory T cells in mouse hepatic allograft tolerance　Jiang, X,M Morita,A Sugioka,M Harada,S Kojo,H Wakao,H Watarai,N Ohkohchi,M Taniguchi,KI Seino　LIVER TRANSPLANTATION　12　7　1112　2006/07
  • 　V alpha 14 NKT cell-triggered IFN-gamma production by Gr-1(+)CD11b(+) cells mediates early graft loss of syngeneic transplanted islets　Y Yasunami,S Kojo,H Kitamura,A Toyofuku,M Satoh,M Nakano,K Nabeyama,Y Nakamura,N Matsuoka,S Ikeda,M Tanaka,J Ono,N Nagata,O Ohara,M Taniguchi　JOURNAL OF EXPERIMENTAL MEDICINE　202　7　913　2005/10
  • 　Dysfunction of T cell receptor AV24AJ18+,BV11+double-negative regulatory natural killer T cells in autoimmune diseases　S Kojo,Y Adachi,H Keino,M Taniguchi,T Sumida　ARTHRITIS AND RHEUMATISM　44　5　1127　2001/05
  • 　Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1.　Satoshi Kojo,Chris Elly,Yohsuke Harada,Wallace Y Langdon,Mitchell Kronenberg,Yun-Cai Liu　Proceedings of the National Academy of Sciences of the United States of America　106　42　17847　2009/10/20
  • 　Essential Roles of SATB1 in Specifying T Lymphocyte Subsets.　Kiyokazu Kakugawa,Satoshi Kojo,Hirokazu Tanaka,Wooseok Seo,Takaho A Endo,Yohko Kitagawa,Sawako Muroi,Mari Tenno,Nighat Yasmin,Yoshinori Kohwi,Shimon Sakaguchi,Terumi Kowhi-Shigematsu,Ichiro Taniuchi　Cell reports　19　6　1176　2017/05/09
  • 　免疫システム開発 免疫細胞発生におけるRunx転写因子の役割(Immunosystem development Roles of Runx Transcription Factors In Immune Cell Development)　Taniuchi Ichiro,Kojo Satoshi,Ebihara Takashi,Seo Wooseok,Tenno Mari　日本免疫学会総会・学術集会記録　46　Proceedings　S8　2017/12
  • 　Clinical significance of side population in ovarian cancer cells.　Shinji Hosonuma,Yoichi Kobayashi,Satoshi Kojo,Haruka Wada,Ken-ichiro Seino,Kazushige Kiguchi,Bunpei Ishizuka　Human cell　24　1　9　2011/03
  • 　Mechanism of NKT cell-mediated transplant tolerance　X. Jiang,S. Kojo,M. Harada,N. Ohkohchi,M. Taniguchi,K.-I. Seino　AMERICAN JOURNAL OF TRANSPLANTATION　7　6　1482　2007/06
  • 　Specific requirement of C-terminal Zn finger motifs in Bcl11b transcription factor for lineage dissection upon receiving positive selection signals in the thymus　Kojo, S.,Seo, W.,Muroi, S.,Taniuchi, I.　European Journal of Immunology　46　260　2016
  • 　The expression and function of CD1d variants in patients with autoimmune disease.　Daisuke Goto,Yohei Yoshiga,Satoshi Kojo,Isao Matsumoto,Satoshi Ito,Akito Tsutsumi,Takayuki Sumida　ARTHRITIS AND RHEUMATISM　54　9　S405　2006/09
  • 　Role of gamma delta T cells in the regulation of HTLV-1 infection　Sato, Tomoo,Muto, Masato,Araya, Natsumi,Kojo, Satoshi,Naoko, Ariyoshi,Maekawa, Ryuji,Utsunomiya, Atae,Seino, Ken-ichiro,Yamano, Yoshihisa　Journal of Neurovirology　18　100　2012
  • 　Side population is increased in paclitaxel-resistant ovarian cancer cell lines regardless of resistance to cisplatin.　Yoichi Kobayashi,Ken-Ichiro Seino,Shinji Hosonuma,Tatsuru Ohara,Hiroaki Itamochi,Seiji Isonishi,Tsunekazu Kita,Haruka Wada,Satoshi Kojo,Kazushige Kiguchi　Gynecologic oncology　121　2　390　2011/05/01
  • 　Research highlights: Immunomodulation.　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　Immunotherapy　1　5　737　2009/09
  • 　Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.　Mari Tenno,Satoshi Kojo,Divine-Fondzenyuy Lawir,Isabell Hess,Katsuyuki Shiroguchi,Takashi Ebihara,Takaho A Endo,Sawako Muroi,Rumi Satoh,Hiroshi Kawamoto,Thomas Boehm,Ichiro Taniuchi　The Journal of experimental medicine　215　2　595　2018/02/05
  • 　Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.　Satoshi Kojo,Hirokazu Tanaka,Takaho A Endo,Sawako Muroi,Ye Liu,Wooseok Seo,Mari Tenno,Kiyokazu Kakugawa,Yoshinori Naoe,Krutula Nair,Kazuyo Moro,Yoshinori Katsuragi,Akinori Kanai,Toshiya Inaba,Takeshi Egawa,Byrappa Venkatesh,Aki Minoda,Ryo Kominami,Ichiro Taniuchi　Nature communications　8　1　702　2017/09/26
  • 　Alternative pathway for the development of Vα14+ NKT cells directly from CD4-CD8- thymocytes that bypasses the CD4+CD8+ stage.　Nyambayar Dashtsoodol,Tomokuni Shigeura,Minako Aihara,Ritsuko Ozawa,Satoshi Kojo,Michishige Harada,Takaho A Endo,Takashi Watanabe,Osamu Ohara,Masaru Taniguchi　Nature immunology　18　3　274　2017/03
  • 　Transcriptional regulator Bhlhe40 works as a cofactor of T-bet in the regulation of IFN-γ production in iNKT cells.　Masatoshi Kanda,Hiroyuki Yamanaka,Satoshi Kojo,Yuu Usui,Hiroaki Honda,Yusuke Sotomaru,Michishige Harada,Masaru Taniguchi,Nao Suzuki,Tatsuya Atsumi,Haruka Wada,Muhammad Baghdadi,Ken-Ichiro Seino　Proceedings of the National Academy of Sciences of the United States of America　113　24　E3394-402　2016/06/14
  • 　Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire.　Nyambayar Dashtsoodol,Tomokuni Shigeura,Ritsuko Ozawa,Michishige Harada,Satoshi Kojo,Takashi Watanabe,Haruhiko Koseki,Manabu Nakayama,Osamu Ohara,Masaru Taniguchi　PloS one　11　4　e0153347　2016
  • 　Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy.　Masaru Taniguchi,Michishige Harada,Nyambayar Dashtsoodol,Satoshi Kojo　Proceedings of the Japan Academy. Series B, Physical and biological sciences　91　7　292　2015
  • 　α-MSH stimulation contributes to TGF-β1 production via MC1R-MITF signaling pathway in melanoma cell　Hayashi Erika,Hachiya Kaori,Kojo Satoshi,Baghdadi Muhammad,Takeuchi Shintaro,Yamanaka Hiroyuki,Abe Hirotak,Wada Haruka,Seino Ken-ichiro　Inflammation and Regeneration　35　5　244　2015
  • 　Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.　Hiroya Kudo,Haruka Wada,Hajime Sasaki,Hyuma Tsuji,Ryo Otsuka,Muhammad Baghdadi,Satoshi Kojo,Tatsuya Chikaraishi,Ken-ichiro Seino　PloS one　9　10　e111826　2014
  • 　Mouse models of human INAD by Pla2g6 deficiency.　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　Histology and histopathology　28　8　965　2013/08
  • 　Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.　Haruka Wada,Satoshi Kojo,Chie Kusama,Naoki Okamoto,Yorino Sato,Bunpei Ishizuka,Ken-ichiro Seino　International immunology　23　1　65　2011/01
  • 　自然リンパ球(2) (ILC1,2,3) Runxタンパク質はILC2の構成的活性を抑制し活性化後のILC2枯渇を予防する(Innate Lymphocyte (ILC1,2,3) Runx proteins suppress constitutive activity of ILC2 and prevent ILC2 exhaustion after activation)　Ebihara Takashi,Kojo Satoshi,Taniuchi Ishiro　日本免疫学会総会・学術集会記録　46　Proceedings　3　2017/12
  • 　Establishment of an improved mouse model for infantile neuroaxonal dystrophy that shows early disease onset and bears a point mutation in Pla2g6.　Haruka Wada,Takuwa Yasuda,Ikuo Miura,Kazuhiko Watabe,Chika Sawa,Hajime Kamijuku,Satoshi Kojo,Masaru Taniguchi,Ichizo Nishino,Shigeharu Wakana,Hisahiro Yoshida,Ken-ichiro Seino　The American journal of pathology　175　6　2257　2009/12
  • 　Suppressor turns into helper　Haruka Wada,Satoshi Kojo,Ken-ichiro Seino　IMMUNOTHERAPY　1　5　737　2009/09
  • 　Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.　Satoshi Kojo,Nighat Yasmin,Sawako Muroi,Mari Tenno,Ichiro Taniuchi　Nature communications　9　1　3593　2018/09/05
  • 　Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity.　Wooseok Seo,Kanako Shimizu,Satoshi Kojo,Arinze Okeke,Terumi Kohwi-Shigematsu,Shin-Ichiro Fujii,Ichiro Taniuchi　Nature communications　11　1　1562　2020/03/26
  • 　Constitutive CD8 expression drives innate CD8+ T-cell differentiation via induction of iNKT2 cells.　Satoshi Kojo,Michiko Ohno-Oishi,Hisashi Wada,Sebastian Nieke,Wooseok Seo,Sawako Muroi,Ichiro Taniuchi　Life science alliance　3　2　e202000642　2020/02　
  • 　Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.　Chizuko Miyamoto,Satoshi Kojo,Motoi Yamashita,Kazuyo Moro,Georges Lacaud,Katsuyuki Shiroguchi,Ichiro Taniuchi,Takashi Ebihara　Nature communications　10　1　447　2019/01/25
  • 　Author Correction: Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.　Chizuko Miyamoto,Satoshi Kojo,Motoi Yamashita,Kazuyo Moro,Georges Lacaud,Katsuyuki Shiroguchi,Ichiro Taniuchi,Takashi Ebihara　Nature communications　10　1　1075　2019/03/01
  • 　Photoswitching CD1d-restriction of TCR by α-GalCer analogs with azobenzene in the middle of acyl chain　Takashi Kanamori,Daisuke Nakabun,Satoshi Kojo,Hiroshi Watarai,Hideya Yuasa　Journal of Photochemistry and Photobiology A: Chemistry　451　115501　2024/06
  • 　Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development.　Keiko Ono,Tomohisa Sujino,Kentaro Miyamoto,Yosuke Harada,Satoshi Kojo,Yusuke Yoshimatsu,Shun Tanemoto,Yuzo Koda,Jiawen Zheng,Kazutoshi Sayama,Tsuyoshi Koide,Toshiaki Teratani,Yohei Mikami,Kaoru Takabayashi,Nobuhiro Nakamoto,Naoki Hosoe,Mariya London,Haruhiko Ogata,Daniel Mucida,Ichiro Taniuchi,Takanori Kanai　Nature communications　14　1　5152　2023/08/24

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