Professor SATO Makoto
Faculty, Affiliation
Institute for Frontier Science Initiative Division of Molecular Neuroscience, Laboratory of Developmental Neurobiology
College and School Educational Field
Division of Medical Sciences, Graduate School of Medical Science
Division of Medicine, Graduate School of Medical Science
Laboratory
Laboratory of Developmental Neurobiology
Academic Background
【Academic background(Doctoral/Master's Degree)】
University of Tokyo Doctor Graduate School of Science Department of Biophysics and Biochemistry 200003 Completed
【Academic background(Bachelor's Degree)】
University of Tokyo Department of Biophysics and Biochemistry 199503
【Degree】
Ph. D.
Career
Current Position Brain/Liver Interface Medicine Research Professor(2012/04/01-)
Associate Professor Kanazawa University, FSO Associate Professor(2008/02/01-2012/03/31)
Assistant Professor University of Tokyo,IMCB Assistant Professor(2007/04/01-2008/01/31)
Research Associate University of Tokyo,IMCB Research Associate(2002/05/01-2007/03/01)
Postdoctral Fellow University of California, San Francisco Postdoctral Fellow(2000/04/01-2002/04/30)
Research fellow of the Japan Society for the Promotion of Science University of California, San Francisco Research fellow of JSPS (PD)(2000/04/01-2001/03/31)
Research fellow of the Japan Society for the Promotion of Science University of Tokyo Research fellow of JSPS (DC2)(1999/01/01-2000/03/31)
Year & Month of Birth
1972/04
Academic Society
Japanese Drosophila Research Conference
The Japan Neuroscience Society
Japan Society of Developmental Biologists
The Molecular Biology Society of Japan
Award
○The Young Scientists’ Prize, The Commendation for Science and Technology by MEXT(2012/04/09)
Specialities
Developmental Neurobiology
Speciality Keywords
Mathematical Modeling,Neural Development,emergence of brain function,neuronal network,cell migration,neuronal diversity,Visual system,Drosophila brain
Research Themes
Developmental mechanisms that govern functional neuronal circuits in the Drosophila visual system
The Drosophila visual system shows structural characteristics shared with mammalian brains. However, developmental mechanisms that produce neuronal diversity and organization of the circuits have been elusive. We found its larval primordium is subdivided into concentric zones specified by expression of conserved transcription factors. Extensive migrations of neurons disrupt the concentric zones during pupal development. Based on these key factors and novel phenomena, we are studying mechanisms that govern functional neuronal circuits in the brain.
Books
- Makoto Sato A Practical Introduction to Mathematical Life Sciences -From MATLAB Programming to Simulations- CORONA Publishing Co., Ltd. 2021/01/08
- Jörg Reichrath, Sandra Reichrath, Shahrzad Bahrampour, Stefan Thor, Chuanxian Wei, Chung-Weng Phang, Renjie Jiao, Makoto Sato, Tetsuo Yasugi, Tetsuichiro Saito, Sergio Córdoba, Carlos Estella, Nicolas Daudet, Magdalena Żak Notch Signaling in Embryology and Cancer Springer 2020/03/14
Papers
- A temporal mechanism that produces neuronal diversity in the Drosophila visual center. DEVELOPMENTAL BIOLOGY 380 12-24 2013/08
- Waves of differentiation in the fly visual system. DEVELOPMENTAL BIOLOGY 380 1-11 2013/08
- Brain-specific-homeobox is required for the specification of neuronal types in the Drosophila optic lobe. DEVELOPMENTAL BIOLOGY 377 90-99 2013/05
- Concentric zones, cell migration and neuronal circuits in the Drosophila visual center Hasegawa, E., Kitada, Y., Kaido, M., Takayama, R., Awasaki, T., Tabata, T. and Sato, M. Development 138 983-993 2011/02
Conference Presentations
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「由来の異なる細胞間相互作用による神経細胞移動制御機構の解明」(2013-2014)
○「動体認識の神経回路とその動作機構」(2012-2015)
○「ショウジョウバエ視覚中枢において神経細胞の移動と形態を結びつける分子機構」(2011-2012)
○「高次視覚中枢におけるWntシグナルによるretinotopy制御機構」(2010-2011)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Neurophysiology(2017)
Classes (Graduate Schools)
○The Function of the Human Body(2017)
○Frontier Life Science(2017)
○Developmental Neurobiology(2017)
○Developmental Neurobiology(2017)
○Frontier Life Science(2017)
○Developmental Neurobiology(2017)
○The Function of the Human Body(2016)
○Developmental Neurobiology(2016)
○Developmental Neurobiology(2016)
○Frontier Life Science(2016)
○An Introduction to Cellular Function(2016)
○Frontier Life Science(2016)
○Developmental Neurobiology(2016)