Professor YAMAZAKI Toshiaki
Faculty, Affiliation
Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Division of Health Sciences, Graduate School of Medical Science
Division of Health Sciences，Graduate School of Medical Science
Department of Physical Therapy，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Department of Physical Therapy, School of Health Sciences. TEL:076-265-2619 FAX:076-234-4372
Academic Background
【Academic background(Doctoral/Master's Degree)】
Kanazawa University Master Graduate School, Division of Medical Sciences 200203 Completed
Kanazawa University Doctor Graduate School, Division of Medical Sciences 200503 Completed
【Academic background(Bachelor's Degree)】
Toyama University 198203
Al. Med. Prof. Kanazawa Univ. 198703
【Degree】
Master of Health Sciences
PhD(Health Sciences)
Career
Kanazawa University(1989/04/01-)
Kanazawa University(1995/10/01-)
Kanazawa University(2004/10/01-)
Kanazawa University(2006/11/01-)
Kanazawa University(2008/04/01-)
Year & Month of Birth
1959/06
Academic Society
Japan Therapeutic Exercise Society
The Japanese Association of Rehabilitation Medicine
Award
Specialities
Physical Therapy
Speciality Keywords
Physical Therapy
Research Themes
Prevention of disuse muscle atrophy
My research focuses on the effects of intermittent weight-bearing or stretching to prevent the progression of disuse muscle atrophy. In experiments using an animal (rat) model of hindlimb suspension, I have been conducting the following analyses:
1) Morphometric analyses (muscle length, circumference, ROM of joint)
2) Physiological analyses (contractile properties; twitch tension, etc. in vitro)
3) Biochemical analyses (protein concentrations; myofibrillar protein, etc.)
4) Histological analyses (HE staining)
5) Histochemical analyses (ATPase staining; classification of muscle fiber type)
6) Immuno-cytochemical analyses (labeling of BrdU, TUNEL, etc.)
Prevention of disuse muscle atrophy
Books
- Clinical Reasoning Part 4 2007/04
Papers
- Effect of electro-motor stimulation on the power production of a maximally stretched muscle Scand J Rehab Med 21 147-150 1989/09
- Effect of short duration stretching for prevention of disuse muscle atrophy in mature rats. Yamazaki T, Tachino K, Haida N, Musha S. 23 6 349-354 1996/09
- Effects of weight bearing intervals on disuse atrophy of rat soleus muscle. J Jpn Phys Ther Assoc 1 1 19-24 1998/06
- The influence of calf muscle pumping and resting position on the volume of the lower leg during and/or whirlpool therapy. 金大医保紀要 23 1 1-7 1999/07
- Non-task-specific training to the latissimi dorsi and oblique abdominal muscles. 金大医保紀要 23 1 9-13 1999/07
- Preventive effect of passive range of motion exercise on denervation- induced muscle atrophy. 金大医保紀要 23 1 55-58 1999/07
- Effect of posture on maximal expiratory pressure. 金大医保紀要 23 2 97-101 1999/12
- Bilateral and unilateral measurement of chest excursion. 金大医保紀要 24 1 1-6 2000/12
- Transient postural away following treadmill walking. 金大医保紀要 24 1 7-13 2000/12
- Adaptation of slow soleus and fast gastrocnemius to isometric exercise in rat. 金大医保紀要 24 1 39-44 2000/12
- Effect of hindlimb re-weighting, low-and high-intensity exercise on disuse atrophy of rat soleus muscle. 金大医保紀要 24 2 1-7 2001/03
- Chest excursion and breathing patterns in the aged. 金大医保紀要 24 2 9-13 2001/03
- Relationship of tibialis anterior muscle reaction time and gait characteristics. 金大医保紀要 24 2 15-19 2001/03
- Effect of electromyographic biofeedback therapy for idiopathic facial palsy. 金大医保紀要 24 2 33-38 2001/03
- Influence of the time when weight bearing is started on disuse atrophy in rat soleus muscle. J Jpn Phys Ther Assoc 4 1 13-18 2001/03
- Influence of weight bearing intervals on the prevention of disuse atrophy in rat soleus muscle J. Tsuruma Health Sci. Soc. 26 1 45-50 2002/12
- Effect of stretch frequency per day in retarding disuse atrophy in rat soleus muscle 3 1 3-7 2003/03
- Influence of hindlimb unweighting and intermittent weight bearing on dynamics of nuclei in rat soleus muscle. 6 1-8 2003/03
- Comparison of the effects of intermittent weight bearing and short duration stretching on disuse atrophy of rat soleus muscles. J Tsuruma Health Sci Med Kanazawa Univ 28 91-96 2004/12
- Effects of intermittent weight-bearing and clenbuterol on disuse atrophy of rat hindlimb muscles. 8 9-20 2005/03
- Effects of short duration weight-bearing on disuse atrophy of rat soleus muscle. 40 6 491-493 2006/06
- Uptake behavior of thallium-201 in hindlimb muscles of rtas J Phys Ther Sci 20 117-122 2008/05
- Age-associated changes in atrophy of the extensor digitorum longus muscle in hindlimb-suspended rats J Phys Ther Sci 20 129-133 2008/05
- Effects of combined stretching and clenbuterol on disuse atrophy in rat soleus muscle. Yamazaki T, Yokogawa M, Tachino K J Jpn Phys Ther Assoc 12 1 13-19 2009/03
- MyoD, myogenin and myosin heavy chain mRNA expression in rat skeletal muscle after a single session of low-intensity treadmill exercise Miyata T, Tanaka S, Yamazaki T J Phys Ther Sci 21 379-383 2009/11
- Effects of walking and weight-bearing exercise on soleus muscle in hindlimb-suspended rat. J Phys Ther Sci 23 385-389 2011/06
- The effect of reloading on disuse muscle atrophy. Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change. Zushi K, Yamazaki T J Jpn Phys Ther Assoc 15 1-8 2012/12
- Influence of passive stretching on inhibition of disuse atrophy and hemodynamics of rat soleus muscle. Kimura S, Inaoka PT, Yamazaki T J Jpn Phys Ther Assoc 15 9-14 2012/12
- Effects of isokinetic passive exercise and isometric muscle contraction on passive stiffness Terada S, Miaki H, Uchiyama K, Hayakawa S, Yamazaki T J Phys Ther Sci 25 1347-1352 2013/10
- The effect of the abdominal drawing-in manoeuvre during forward steps. Madokoro S, Miaki H, Yamazaki T. J Phys Ther Sci 26 6 889-893 2014/06
- Effects of static interventions on disuse atrophy of the rat soleus muscle at different sites along its longitudinal axis. Miyachi R, Yamazaki T. J Phys Ther Sci 27 2317-2321 2015/07
- Effect of hindlimb unloading and reloading on the soleus and plantaris muscles in diabetic rats. Madokoro S, Inaoka PT, Tanaka S, Yamazaki T. J Phys Ther Sci 30 1150-1155 2018/09/04
- Morphological changes of lower leg muscles according to ankle joint position during sitting evaluated by gravity mri in young females. Miyachi R, Yamazaki T, Ohno N, Miyati T. J Phys Ther Sci 31 488-492 2019/06/01
- Relationship between muscle cross-sectional area by MRI and muscle thickness by ultrasonography of the triceps surae in the sitting position. Miyachi R, Yamazaki T, Ohno N, Miyati T. Healthcare 8 2 166 2020/06/30
- Fast repetitive stretch suppresses denervation‐induced muscle fibrosis. Tanaka S, Inaoka PT, Yano A, Nakagawa T, Yamazaki T. Muscle Nerve 62 746-756 2020/09/07
- Contributions of muscle elasticity and lateral slide of the transversus abdominis to lumbar stability Shimizu I, Miaki H, Mizuno K, Azuma N, Nakagawa T, yamazaki T J Sport Rehabil 2020/11/23
- Morphological changes in the long axis of the lower leg muscles during isometric contraction in the sitting position. Miyachi R, Yamazaki T, Ohno N, Miyati T. J Phys Ther Sci 32 828-832 2020/12/11
- Blood lipid profile changes in type 2 diabetic rats after tail suspension and reloading Tanaka S, Madokoro S, Inaoka PT, Yamazaki T Lipids in Health and Disease 20 2021/08/01
- Preventive effect of weight-bearing in disuse muscle atrophy of diabetic rats Madokoro S, Inaoka PT, Tanaka S, Yamazaki T. J Wellness Health Care 45 1 33-40 2021/08/02
- Effects of long-term treatment with dietary theobromine on rat skeletal muscles. Tanaka S, Sugimoto N, Ohno-Shosaku T, Madokoro S, Inaoka PT, Yamazaki T. Molecular Biology Reports 28 2022/02/28
- Reliability of lower leg muscle thickness measurement along the long axis of the muscle using ultrasound imaging in a sitting position. Miyachi R, Kanazawa Y, Fujii Y, Ohno N, Miyati T, Yamazaki T. J Phys Ther Sci 34 515-521 2022/07/01
- Relationship between ankle-joint angle during dynamic balance task and ankle-joint proprioception in chronic ankle-instability individuals. Miyachi R, Kanazawa Y, Fijii Y, Yamazaki T J Sports Med Phys Fitness 2022/07/11
- Association of life-space with light-intensity and moderate to vigorous-intensity physical activity in older adults using daycare rehabilitation facilities. Souma K, Yokogawa M, Uchiyama K, Madokoro S, Miaki H, Yamazaki T Physiotherapy Theory and Practice 2022/12/03
- Relationship between pelvic floor muscle function and changes in lumbar spine and hip motion due to pelvic floor muscle contraction. Miyachi R, Madokoro S, Ohno N, Miyati T, Yamazaki T J Back Musculoskelet Rehabil 2022/12/15
- Division of loading time in reloading the disused atrophic soleus muscle induces proximal muscle injury. Miyachi R, Morita Y, Yamazaki T J Phys Ther Sci 35 3 193-198 2023/03/01
- Development of connective tissue area increases by initial impact with high-intensity exercise after reloading in rat soleus muscle. Tanaka S, Inaoka PT, Madokoro S, Yamazaki T. Am J Phys Med Rehabil 2023/07/01
- The components of lumbar motor control are not inter-related. Miyachi R, Nagamori Y, Kanazawa Y, Yamazaki T J Musculoskeletal and Neuronal Interactions 2024/01/29
- Effects of 6 weeks of whole-body vibration training on ankle motor control: A randomized controlled trial Miyachi R, Kanazawa Y, Fujii Y, Kitagawa T, Yamazaki J Sports Medicine and Physical Fitness 2024/02/13
Conference Presentations
- The effect of the abdominal drawing-in manoeuvre during forward steps.(conference：17th International WCPT Congress)(2015/05/03)
- Time-course influence of weight-bearing stimulation on muscle fibers with disuse muscle atrophy: based on longitudinal regions in rat soleus muscle.(conference：17th International WCPT Congress.)(2015/05/04)
- Effects of static interventions on disuse atrophy of rat soleus muscle depend on the longitudinal sites.(conference：17th International WCPT Congress)(2015/05/04)
- Time-course changes in disuse atrophy of the soleus muscle induced by intermittent short-time stretching in rats.(conference：WCPT-AWP & PTAT Congress 2017)(2017/06/28)
- Analysis of gastrocnemius muscle morphology with changes in the ankle joint position while sitting in adult women using Gravity MRI.(conference：WCPT-AWP & PTAT Congress 2017)(2017/06/29)
- The effects of hindlimb unloading and reloading on the soleus and plantaris muscles in diabetic rats.(conference：13th International Society of Physical and Rehabilitation Medicine World Congress (ISPRM 2019).)(2019/06/09)
- Effects of a gradually increased load on the progression of disuse muscle atrophy of the rat soleus muscle. (conference：ACPT Congress 2016)(2016/10/07)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「骨格筋萎縮の進行抑制に及ぼすストレッチとアドレナリン受容体作用薬の併用効果」(2005-)
○「骨格筋衛星細胞活性化とMyoDファミリー発現を指標とした至適運動負荷量の設定」(2008-)
○「廃用性筋萎縮抑制効果の長軸部位別検証による臨床視点的プログラムの構築」(2012-2015)
○「長軸部位を考慮した廃用性筋萎縮予防介入の効果検証」(2016-2019)
○「座位時間を活用した下腿筋萎縮抑制の長軸部位別効果検証」(2020-2022)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Measurement and Evaluation 1(2022)
○Activities of Daily Living 1(2022)
○Measurement and Evaluation 3(2022)
○Activities of Daily Living 2(2022)
○Measurement and Evaluation 2(2022)
○Environmental and the Physical Therapist(2022)
○Activities of Daily Living 2(2022)
○Measurement and Evaluation 2(2022)
○Measurement and Evaluation 3(2022)
○Measurement and Evaluation 3(2021)
○Measurement and Evaluation 2(2021)
○Measurement and Evaluation 1(2021)
○Activities of Daily Living 1(2021)
○Environmental and the Physical Therapist(2021)
○Activities of Daily Living 2(2021)
○Clinical Internship 2(2020)
○Clinical Internship 1(2020)
○Environmental and the Physical Therapist(2020)
○Activities of Daily Living 2(2020)
○Activities of Daily Living 1(2020)
○Activities of Daily Living 1(2020)
○Measurement and Evaluation 1(2020)
○Measurement and Evaluation 3(2020)
○Measurement and Evaluation 2(2020)
○Introduction to Region-studies(2019)
○Freshman Seminar I(2019)
○Presentation and Debate (Freshman Seminar II)(2019)
○Orthotics(2019)
○Activities of Daily Living 2(2019)
○Activities of Daily Living 1(2019)
○Measurement and Evaluation 3(2019)
○Measurement and Evaluation 1(2019)
○Measurement and Evaluation 2(2019)
○Measurement and Evaluation 2(2018)
○Orthotics(2018)
○Measurement and Evaluation 1(2018)
○Presentation and Debate (Freshman Seminar II)(2018)
○Activities of Daily Living 2(2018)
○Activities of Daily Living 1(2018)
○Measurement and Evaluation 3(2018)
○Presentation and Debate (Freshman Seminar II)(2017)
○Orthotics(2017)
○Activities of Daily Living 2(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Measurement and Evaluation 3(2017)
○Measurement and Evaluation 1(2017)
○Measurement and Evaluation 2(2017)
○Activities of Daily Living 1(2017)
○Measurement and Evaluation 2(2016)
○Measurement and Evaluation 1(2016)
○Measurement and Evaluation 3(2016)
○Activities of Daily Living 1(2016)
○Activities of Daily Living 2(2016)
○Orthotics(2016)
Classes (Graduate Schools)
○Preventive Medicine(2021)
○Impairment Advanced Analysis:Research(2020)
○Adv. Tech. for Functional Restoration: Seminar(2020)
○Adv. Tech. for Functional Restoration: Lecture(2020)
○Impairment Analysis Science:Reseach(2020)
○Preventive Medicine(2020)
○Adv. Therapeutics in Functional Restoration: Semi.(2020)
○Adv. Therapeutics in Functional Restoration: Lec.(2020)
○Research Design in Physical Therapy: Lecture(2020)
○Impairment Advanced Analysis:Research(2019)
○Adv. Tech. for Functional Restoration: Seminar(2019)
○Adv. Tech. for Functional Restoration: Lecture(2019)
○Impairment Analysis Science:Reseach(2019)
○Adv. Therapeutics in Functional Restoration: Semi.(2019)
○Adv. Therapeutics in Functional Restoration: Lec.(2019)
○Research Design in Physical Therapy: Lecture(2019)
○Preventive Medicine(2019)
○Impairment Advanced Analysis:Research(2018)
○Adv. Tech. for Functional Restoration: Seminar(2018)
○Adv. Tech. for Functional Restoration: Lecture(2018)
○Impairment Analysis Science:Reseach(2018)
○Adv. Therapeutics in Functional Restoration: Semi.(2018)
○Adv. Therapeutics in Functional Restoration: Lec.(2018)
○Research Design in Physical Therapy: Lecture(2018)
○Preventive Medicine(2018)
○Adv. Therapeutics in Functional Restoration: Semi.(2017)
○Adv. Therapeutics in Functional Restoration: Lec.(2017)
○Impairment Advanced Analysis:Research(2017)
○Adv. Tech. for Functional Restoration: Lecture(2017)
○Adv. Tech. for Functional Restoration: Seminar(2017)
○Research Design in Physical Therapy: Lecture(2017)
○Impairment Analysis Science:Reseach(2017)
○Research Design in Physical Therapy: Lecture(2016)
○Adv. Therapeutics in Functional Restoration: Lec.(2016)
○Adv. Therapeutics in Functional Restoration: Semi.(2016)
○Impairment Analysis Science:Reseach(2016)
○Adv. Tech. for Functional Restoration: Lecture(2016)
○Adv. Tech. for Functional Restoration: Seminar(2016)
○Impairment Advanced Analysis:Research(2016)