Professor INAZU Akihiro
Faculty, Affiliation
Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences Clinical Laboratory Science
Professor, Graduate Course of Medical Science and Technology
College and School Educational Field
Division of Health Sciences, Graduate School of Medical Science
Division of Health Sciences，Graduate School of Medical Science
Department of Laboratory Sciences，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Akihiro INAZU Lab
Academic Background
【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Graduate School, Division of Medicine 1991
【Academic background(Bachelor's Degree)】
Kanazawa University 1986
Career
Kanazawa National Tax Bureau Medical Office(1992/04/01-1997/03/31)
Kanazawa University School of Health Sciences(1997/04/01-2005/03/31)
Kanazawa University Graduate School of Medical Science(2005/04/01-2009/03/31)
Year & Month of Birth
1962/01
Academic Society
JSCC
JSLM
AACC
ASBMB
Award
Specialities
Metabolism、Laboratory science
Speciality Keywords
Lipid Metabolism, Atherosclerosis, Clinical Chemistry
Research Themes
Function of serum high-density lipoproteins
CETP inhibitor
Molecular basis of secondary hyperlipidemia, FH-like syndrome and combined hyperlipidemia
Books
- Akihiro Inazu The HDL handbook 3rd Edition Academic Press, Elsevier 2017/02/22
Papers
- Putative Pathogenic Variants of ABCG5 and ABCG8 of Sitosterolemia in Patients With Hyper-Low-Density Lipoprotein Cholesterolemia Nobuko Kojima; Hayato Tada; Akihiro Nomura; Soichiro Usui; Kenji Sakata; Kenshi Hayashi; Atsushi Nohara; Akihiro Inazu; Masa-aki Kawashiri; Masayuki Takamura Journal of Lipid and Atherosclerosis 13 1 53-60 2023/10/04
- A teenager boy with a novel variant of Sitosterolemia presented with pancytopenia V Gok, H Tada, M E Dogan, ...., A Inazu, E Unal Clin Chim Acta 529 61-66 2022/02/12
- Prevalence, self-awareness, and LDL cholesterol levels among patients highly suspected as familial hypercholesterolemia in a Japanese community Hayato Tada, Junichi Shibayama, Tetsuo Nishikawa, Hirofumi Okada, Akihiro Nomura, Soichiro Usui, Kenji Sakata, Atsushi Hashiba, Akihiro Inazu, Masayuki Takamura, Masa-aki Kawashiri Practical Laboratory Medicine 22 e038623 2020/10/19
- Serum sitosterol level predicting ABCG5 or ABCG8 genetic mutations Nobuko Kojima, Hayato Tada, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Atsushi Nohara, Akihiro Inazu, Masayuki Takamura, Masa-aki Kawashiri Clin Chim Acta 507 11-16 2020
- Clinical whole exome sequencing in severe hypertriglyceridemia Tada H, Nomura A, Okada H, Nakahashi T, Nozue T, Hayashi K, Nohara A, Yagi K, Inazu A, Michishita I, Mabuchi H, Yamagishi M, Kawashiri MA. Clin Chim Acta 488 31-39 2019/01
- HDL3 Cholesterol Levels in an Elderly Population Akihiro Inazu J Atheroscler Thromb 24 2018/01/25
- Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease. Nomura A, Won HH, Khera AV, Takeuchi F, Ito K, McCarthy S, Emdin CA, Klarin D, Natarajan P, Zekavat SM, Gupta N, Peloso GM, Borecki IB, Teslovich TM, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartze DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Juang JJ, Hsiung CA, Lin SY, Wang JS, Tada H, Kawashiri MA, Inazu A, Yamagishi M, Katsuya T, Nakashima E, Nakatochi M, Yamamoto K, Yokota M, Momozawa Y, Rotter JI, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer CJ, Abecasis GR, Saleheen D, Kubo M, Kato N, Ida Chen YD, Dewey FE, Kathiresan S. Circ Res 121 1 81-88 2017/06/23
- Novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic subjects Ohtani, Rumiko; Inazu, Akihiro; Noji, Yoshihiro; Wakasugi, Takanobu; Miwa, Kenji; Tada, Hayato; Kawashiri, Masaaki; Noguchi, Tohru; Nohara, Atsushi; Kobayashi, Junji; Koizumi, Junji; Yamagishi, Masakazu; Mabuchi, Hiroshi Clinica Chimica Acta 413 42130 537-543 2012/03/22
- Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of HDL cholesterol JOURNAL OF CLINICAL INVESTIGATION 94 5 1872-1882 1994/11
- Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation NEW ENGLAND JOURNAL OF MEDICINE 323 18 1234-1238 1990/11
- Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins. Brown ML, Inazu A, Hesler CB, Agellon LB, Mann C, Whitlock ME, Marcel YL, Milne RW, Koizumi J, Mabuchi H, Takeda R, Tall AR. Nature 342 6248 448-51 1989/11/23
- Anti-atherogenicity of HDL and the assay for HDL function Akihiro Inazu, Yutaka Takino 45 18-24 2016/01
Conference Presentations
- Experience in editorial board of Clin Chim Acta(2023/11/18)
- Etiology of hyperalphalipoproteinemia and CETP inhibitors(2020/10/30)
- Hyperalphalipoproteinemia and HDL function test(2019/09/27)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
○HDL function assay development
○Lipid lowering agent, HDL modulating agent
Pharmacogenetics
○Gene and environment interaction in human cardiovascular disease
Grant-in-Aid for Scientific Research
○「代謝異常関連脂肪肝におけるANGPTL8および小胞体ストレスの役割と先制医療の可能性」(2024-2026)
○「複合型高脂血症発症に関与する肝性リパーゼ活性・内因性リパーゼインヒビターの役割」(2020-2024)
○「コレステリルエステル転送蛋白欠損におけるリン脂質代謝異常と抗糖尿病性」(2012-2014)
○「パーソナルヘルスレコードを活用した診療（オンライン診療中心とした）における行動変容に関する研究
」(2022-2024)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Clinial Practice of Clinical Chemistry(2024)
○Lecture on Clinical Laboratory Management(2024)
○Pathophysiology 2(2024)
○Clinical Chemistry Laboratory(2024)
○Clinical Chemistry Laboratory(2024)
○Clinical Chemistry(2024)
○Metabolism of Drugs and Xenobiotics(2024)
○Physiology(2024)
○Physiology(2024)
○Human Physiology(2021)
○Clinical Chemistry(2021)
○Environmental Hygiene-Laboratory and Field Work(2021)
○Metabolism of Drugs and Xenobiotics(2021)
○Basic Health Science 1(2021)
○Basic Health Science 2(2021)
○Clinical Chemistry(2021)
○Clinical Chemistry Laboratory(2021)
○Pathophysiology 2(2021)
○Clinial Practice of Clinical Chemistry(2021)
Classes (Graduate Schools)
○Biological Information Analysis: Seminar(2021)
○Biological Information Analysis: Lecture(2021)
○Molecular Biology for Laboratory Medicine:Research(2021)
○Research Design in Health Science(Clinical): Lecture(2021)