last modified：2024/12/03
Professor HORI Osamu
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences Department of Neuroanatomy
Dean, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University
College and School Educational Field
Division of Medical Sciences, Graduate School of Medical Science
Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Department of Neuroanatomy TEL:076-265-2162 FAX:076-234-4222
Academic Background
【Academic background(Bachelor's Degree)】
Osaka University 198903
Career
Year & Month of Birth
1962/11
Academic Society
Japan Neuroscience Society
Award
Specialities
Nerve anatomy/Neuropathology
Speciality Keywords
glia, neuronal death, endoplasmic reticulum stress
Research Themes
Stress Response of Cells in Central Nervous System
Development of neuronal cell protecting drugs and anti-stress drugs
Books
Papers
- Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside Haruhiro Higashida,Kazumi Furuhara,Olga Lopatina,Maria Gerasimenko,Osamu Hori,Tsuyoshi Hattori,Yasuhiko Hayashi,Stanislav M. Cherepanov,Anna A. Shabalova,Alla B. Salmina,Kana Minami,Teruko Yuhi,Chiharu Tsuji,PinYue Fu,Zhongyu Liu,Shuxin Luo,Anpei Zhang,Shigeru Yokoyama,Satoshi Shuto,Mizuki Watanabe,Koichi Fujiwara,Sei-ichi Munesue,Ai Harashima,Yasuhiko Yamamoto Frontiers in Neuroscience 16 2022/07/07
- ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions Takashi Tanaka,Dinh Thi Nguyen,Nichakarn Kwankaew,Megumi Sumizono,Reika Shinoda,Hiroshi Ishii,Mika Takarada-Iemata,Tsuyoshi Hattori,Seiichi Oyadomari,Nobuo Kato,Kazutoshi Mori,Osamu Hori Neurochemical Research 2023/02/28
- Localized astrogenesis regulates gyrification of the cerebral cortex. Yohei Shinmyo,Kengo Saito,Toshihide Hamabe-Horiike,Narufumi Kameya,Akitaka Ando,Kanji Kawasaki,Tung Anh Dinh Duong,Masataka Sakashita,Jureepon Roboon,Tsuyoshi Hattori,Takayuki Kannon,Kazuyoshi Hosomichi,Michal Slezak,Matthew G Holt,Atsushi Tajima,Osamu Hori,Hiroshi Kawasaki Science Advances 8 10 eabi5209 2022/03/11
- Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes Jureepon Roboon,Tsuyoshi Hattori,Dinh Thi Nguyen,Hiroshi Ishii,Mika Takarada-Iemata,Takayuki Kannon,Kazuyoshi Hosomichi,Takashi Maejima,Kengo Saito,Yohei Shinmyo,Michihiro Mieda,Atsushi Tajima,Hiroshi Kawasaki,Osamu Hori Frontiers in Cellular Neuroscience 16 2022/10/06
- Brain injury triggers cell‐type‐specific and time‐dependent endoplasmic reticulum stress responses Qiyan Fan,Mika Takarada‐Iemata,Nahoko Okitani,Takashi Tamatani,Hiroshi Ishii,Tsuyoshi Hattori,Sumiko Kiryu‐Seo,Hiroshi Kiyama,Osamu Hori Glia 2022/11/22
- The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity. Dinh Thi Nguyen,Thuong Manh Le,Tsuyoshi Hattori,Mika Takarada-Iemata,Hiroshi Ishii,Jureepon Roboon,Takashi Tamatani,Takayuki Kannon,Kazuyoshi Hosomichi,Atsushi Tajima,Shusuke Taniuchi,Masato Miyake,Seiichi Oyadomari,Takashi Tanaka,Nobuo Kato,Shunsuke Saito,Kazutoshi Mori,Osamu Hori Scientific reports 11 1 13086 2021/06/22
- Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination. Jureepon Roboon,Tsuyoshi Hattori,Hiroshi Ishii,Mika Takarada-Iemata,Thuong Manh Le,Yoshitake Shiraishi,Noriyuki Ozaki,Yasuhiko Yamamoto,Akira Sugawara,Hiroshi Okamoto,Haruhiro Higashida,Yasuko Kitao,Osamu Hori Frontiers in cellular neuroscience 13 258 258 2019
- Caspase-1 initiates apoptosis in the absence of gasdermin D. Tsuchiya K,Nakajima S,Hosojima S,Thi Nguyen D,Hattori T,Manh Le T,Hori O,Mahib MR,Yamaguchi Y,Miura M,Kinoshita T,Kushiyama H,Sakurai M,Shiroishi T,Suda T Nat Commun. 10 1 2091 2019/05
- N-myc downstream-regulated gene 2 protects blood–brain barrier integrity following cerebral ischemia Mika Takarada-Iemata,Akifumi Yoshikawa,Hieu Minh Ta,Nahoko Okitani,Takumi Nishiuchi,Yasuhiro Aida,Tomoya Kamide,Tsuyoshi Hattori,Hiroshi Ishii,Takashi Tamatani,Thuong Manh Le,Jureepon Roboon,Yasuko Kitao,Tomohiro Matsuyama,Mitsutoshi Nakada,Osamu Hori GLIA 66 7 1432 2018/07/01
- Abnormal social behavior and altered gene expression in mice lacking NDRG2. Mika Takarada-Iemata,Toru Yoshihara,Nahoko Okitani,Keiko Iwata,Tsuyoshi Hattori,Hiroshi Ishii,Jureepon Roboon,Dinh Thi Nguyen,Qiyan Fan,Takashi Tamatani,Takumi Nishiuchi,Masahide Asano,Osamu Hori Neuroscience letters 743 135563 2021/01/19
- Deletion of CD38 and supplementation of NAD+ attenuate axon degeneration in a mouse facial nerve axotomy model. Yuji Takaso,Masao Noda,Tsuyoshi Hattori,Jureepon Roboon,Miyako Hatano,Hisashi Sugimoto,Charles Brenner,Yasuhiko Yamamoto,Hiroshi Okamoto,Haruhiro Higashida,Makoto Ito,Tomokazu Yoshizaki,Osamu Hori Scientific reports 10 1 17795 2020/10/20
- Deletion of Atf6 alpha impairs astroglial activation and enhances neuronal death following brain ischemia in mice Yoshikawa, Akifumi;Kamide, Tomoya;Hashida, Koji;Hieu Minh Ta;Inahata, Yuki;Takarada-Iemata, Mika;Hattori, Tsuyoshi;Mori, Kazutoshi;Takahashi, Ryosuke;Matsuyama, Tomohiro;Hayashi, Yutaka;Kitao, Yasuko;Hori, Osamu JOURNAL OF NEUROCHEMISTRY 132 3 342-353 2015/01/01
- Soluble receptor for advanced glycation end products as a biomarker of symptomatic vasospasm in subarachnoid hemorrhage. Aida Y,Kamide T,Ishii H,Kitao Y,Uchiyama N,Nakada M,Hori O J Neurosurg 1 2019/11
- SERP1/RAMP4 stabilizes membrane proteins during stress and facilitates subsequent glycosylation. JOURNAL OF CELL BIOLOGY 147 1195-1204 1999/12
- Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease JOURNAL OF CELL BIOLOGY 157 1151-1160 2002/06
- ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson's Disease Koji Hashida,Yasuko Kitao,Hirofumi Sudo,Yoshitaka Awa,Shinichiro Maeda,Kazutoshi Mori,Ryosuke Takahashi,Munekazu Iinuma,Osamu Hori PLOS ONE 7 10 e47950 2012/10
- Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum. Haruhiro Higashida,Shin-Ya Kamimura,Takeshi Inoue,Osamu Hori,Mohammad Saharul Islam,Olga Lopatina,Chiharu Tsuji Journal of neural transmission (Vienna, Austria : 1996) 125 1 17 2018/01
- ORP150 protects against hypoxia/ischemia-induced neuronal death. NATURE MEDICINE 7 317-323 2001/12
- Role of Herp in the endoplasmic reticulum stress response. GENES TO CELLS 9 5 457-469 2004/05
- Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. MOLECULAR AND CELLULAR BIOLOGY 26 2006
- Does ORP150/HSP12A protect dopaminergic neurons against MPTP/MPP(+)-induced neurotoxicity? 9, 589-595 2007
- Methoxyflavones protect cells against endoplasmic reticulum (ER) stress and neurotoxin. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 292 1, C353-C361 2007
- Vaticanol B, a resveratrol tetramer, regulates endoplasmic reticulum (ER) stress and inflammation. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 293 1 C411-8 2007
- A dibenzoylmethane (DBM) derivative protects dopaminergic neurons against both oxidative stress and endoplamic reticulum (ER) stress. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 293 6, C1884-94 2007
- Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction. NEUROCHEMISTRY INTERNATIONAL 2008
- Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport K Ozawa,T Kondo,O Hori,Y Kitao,DM Stern,W Eisenmenger,S Ogawa,T Ohshima JOURNAL OF CLINICAL INVESTIGATION 108 1 41 2001/07
- Expression of a novel RNA-splicing factor, RA301/Tra2 beta, in vascular lesions and its role in smooth muscle cell proliferation Y Tsukamoto,N Matsuo,K Ozawa,O Hori,T Higashi,J Nishizaki,N Tohnai,Nagata, I,K Kawano,C Yutani,S Hirota,Y Kitamura,DM Stern,S Ogawa AMERICAN JOURNAL OF PATHOLOGY 158 5 1685 2001/05
- ORP150 protects against hypoxia/ischemia-induced neuronal death M Tamatani,T Matsuyama,A Yamaguchi,N Mitsuda,Y Tsukamoto,M Taniguchi,YH Che,K Ozawa,O Hori,H Nishimura,A Yamashita,M Okabe,H Yanagi,DM Stern,S Ogawa,M Tohyama NATURE MEDICINE 7 3 317 2001/03
- Amyloid beta-peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress SD Yan,YC Zhu,ED Stern,YYC Hwang,O Hori,S Ogawa,MP Frosch,ES Connolly,R McTaggert,DJ Pinsky,S Clarke,DM Stern,R Ramasamy JOURNAL OF BIOLOGICAL CHEMISTRY 275 35 27100 2000/09
- 150-kDa oxygen-regulated protein (ORP150) functions as a novel molecular chaperone in MDCK cells Y Bando,S Ogawa,A Yamauchi,K Kuwabara,K Ozawa,O Hori,H Yanagi,M Tamatani,M Tohyama AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 278 6 C1172 2000/06
- ORP150 (150 kDa Oxygen Regulated Protein) suppresses hypoxia-induced cell death. K Ozawa,O Hori,M Tamatani,S Ogawa FRONTIERS OF THE MECHANISMS OF MEMORY AND DEMENTIA 1200 61 2000
- Induction of 72-kDa inducible heat shock protein (HSP72) in cultured rat astrocytes after energy depletion N Imuta,S Ogawa,Y Maeda,K Kuwabara,O Hori,H Ueda,T Yanagihara,M Tohyama JOURNAL OF NEUROCHEMISTRY 70 2 550 1998/02
- Adsorption of circulating denDritic and monocytic cells by textured surface left ventricular assist devices: A model for sustained cellular activation of procoagulant and proinflammatory responses TB Spanier,MC Oz,O Hori,JF Li,HR Levin,S Itescu,EA Rose,DM Stern,AM Schmidt CIRCULATION 94 8 4061 1996/10
- Expression of mitochondrial tricarboxylate carrier TCC mRNA and protein in the rat brain S Miyake,T Yamashita,M Taniguchi,M Tamatani,K Sato,Y Kawai,E Senba,N Mitsuda,O Hori,A Yamaguchi,M Tohyama MOLECULAR BRAIN RESEARCH 100 1-2 67 2002/04
- Immunohistochemical detection of the 150-kDa oxygen-regulated protein in bladder cancer H Asahi,K Koshida,O Hori,S Ogawa,M Namiki BJU INTERNATIONAL 90 4 462 2002/09
- A novel presenilin-2 splice variant in human Alzheimer's disease brain tissue N Sato,O Hori,A Yamaguchi,JC Lambert,MC Chartier-Harlin,PA Robinson,A Delacourte,AM Schmidt,T Furuyama,K Imaizumi,M Tohyama,T Takagi JOURNAL OF NEUROCHEMISTRY 72 6 2498 1999/06
- Stress-associated endoplasmic reticulum protein 1 (SERP1)/ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation A Yamaguchi,O Hori,DM Stern,E Hartmann,S Ogawa,M Tohyama JOURNAL OF CELL BIOLOGY 147 6 1195 1999/12
- Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases Akihiko Taguchi,David C. Blood,Gustavo Del Toro,Anthony Canet,Daniel C. Lee,Wu Qu,Nozomu Tanjl,Yan Lu,Evanthia Lalla,Caifeng Fu,Marlon A. Hofmann,Thomas Kislinger,Mark Ingram,Amy Lu,Hidekazu Tanaka,Osamu Hori,Satoshi Ogawa,David M. Stern,Ann Marie Schmidt Nature 405 6784 354 2000/05/18
- Antitumor effect of reduction of 150-kDa oxygen-regulated protein expression in human prostate cancer cells T. Miyagi,O. Hori,M. Egawa,H. Kato,Y. Kitagawa,H. Konaka,K. Ozawa,K. Koshida,T. Uchibayashi,S. Ogawa,M. Namiki Molecular Urology 5 2 79 2001
- The receptor for advanced glycation end-products has a central role in mediating the effects of advanced glycation end-products on the development of vascular disease in diabetes mellitus O Hori,SD Yan,S Ogawa,K Kuwabara,M Matsumoto,D Stern,AM Schmidt NEPHROLOGY DIALYSIS TRANSPLANTATION 11 13 1996
- THE MONONUCLEAR PHAGOCYTE INTERACTION SITE OF BETA-2-MICROGLOBULIN MODIFIED BY GLYCATION IS THE RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS AM SCHMIDT,O HORI,SD YAN,S OGAWA,D STERN,T MIYATA CIRCULATION 90 4 233 1994/10
- Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain K Kuwabara,M Matsumoto,J Ikeda,O Hori,S Ogawa,Y Maeda,K Kitagawa,N Imuta,T Kinoshita,DM Stern,H Yanagi,T Kamada JOURNAL OF BIOLOGICAL CHEMISTRY 271 9 5025 1996/03
- Exposure of astrocytes to hypoxia reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6 O Hori,M Matsumoto,K Kuwabara,Y Maeda,H Ueda,T Ohtsuki,T Kinoshita,S Ogawa,DM Stern,T Kamada JOURNAL OF NEUROCHEMISTRY 66 3 973 1996/03
- RAGE - A novel cellular receptor for advanced glycation end products AM Schmidt,O Hori,R Cao,SD Yan,J Brett,JL Wautier,S Ogawa,K Kuwabara,M Matsumoto,D Stern DIABETES 45 S77 1996/07
- Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress HM Lander,JM Tauras,JS Ogiste,O Hori,RA Moss,AM Schmidt JOURNAL OF BIOLOGICAL CHEMISTRY 272 28 17810 1997/07
- The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta(2)microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway - Implications for the pathogenesis of dialysis-related amyloidosis T Miyata,O Hori,JH Zhang,SD Yan,L Ferran,Y Lida,AM Schmidt JOURNAL OF CLINICAL INVESTIGATION 98 5 1088 1996/09
- Potentiating effect of morphine upon d-methamphetamine-induced hyperthermia in mice. Effects of naloxone and haloperidol Masumi Funahashi,Hirofumi Kohda,Osamu Hori,Hirohito Hayashida,Hiroshi Kimura Pharmacology, Biochemistry and Behavior 36 2 345 1990
- THE RECEPTOR FOR ADVANCED GLYCATION END-PRODUCTS (RAGE) IS A CELLULAR-BINDING SITE FOR AMPHOTERIN - MEDIATION OF NEURITE OUTGROWTH AND COEXPRESSION OF RAGE AND AMPHOTERIN IN THE DEVELOPING NERVOUS-SYSTEM O HORI,J BRETT,T SLATTERY,R CAO,JH ZHANG,JX CHEN,M NAGASHIMA,ER LUNDH,S VIJAY,D NITECKI,J MORSER,D STERN,AM SCHMIDT JOURNAL OF BIOLOGICAL CHEMISTRY 270 43 25752 1995/10
- HYPOXIA/REOXYGENATION-MEDIATED INDUCTION OF ASTROCYTE INTERLEUKIN-6 - A PARACRINE MECHANISM POTENTIALLY ENHANCING NEURON SURVIVAL Y MAEDA,M MATSUMOTO,O HORI,K KUWABARA,S OGAWA,SD YAN,T OHTSUKI,T KINOSHITA,T KAMADA,DM STERN JOURNAL OF EXPERIMENTAL MEDICINE 180 6 2297 1994/12
- ADVANCED GLYCATION END-PRODUCTS (AGES) ON THE SURFACE OF DIABETIC ERYTHROCYTES BIND TO THE VESSEL WALL VIA A SPECIFIC RECEPTOR INDUCING OXIDANT STRESS IN THE VASCULATURE - A LINK BETWEEN SURFACE-ASSOCIATED AGES AND DIABETIC COMPLICATIONS JL WAUTIER,MP WAUTIER,AM SCHMIDT,GM ANDERSON,O HORI,C ZOUKOURIAN,L CAPRON,O CHAPPEY,SD YAN,J BRETT,PJ GUILLAUSSEAU,D STERN PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 16 7742 1994/08
- METABOLIC AND BIOSYNTHETIC ALTERATIONS IN CULTURED ASTROCYTES EXPOSED TO HYPOXIA REOXYGENATION O HORI,M MATSUMOTO,Y MAEDA,H UEDA,T OHTSUKI,DM STERN,T KINOSHITA,S OGAWA,T KAMADA JOURNAL OF NEUROCHEMISTRY 62 4 1489 1994/04
- Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone K Ozawa,Y Tsukamoto,O Hori,Y Kitao,H Yanagi,DM Stern,S Ogawa CANCER RESEARCH 61 10 4206 2001/05
- Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia A Yamaguchi,M Taniguchi,O Hori,S Ogawa,N Tojo,N Matsuoka,S Miyake,K Kasai,H Sugimoto,M Tamatani,T Yamashita,M Tohyama JOURNAL OF BIOLOGICAL CHEMISTRY 277 1 623 2002/01
- Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death M Miyazaki,K Ozawa,O Hori,Y Kitao,T Matsushita,S Ogawa,T Matsuyama JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 22 8 979 2002/08
- Transmission of cell stress from endoplasmic reticulum to mitochondria Osamu Hori,Fusae Ichinoda,Takashi Tamatani,Atsushi Yamaguchi,Naoya Sato,Kentaro Ozawa,Yasuko Kitao,Mayuki Miyazaki,Heather P. Harding,David Ron,Masaya Tohyama,David M Stern,Satoshi Ogawa Journal of Cell Biology 157 7 1151 2002/06/24
- Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity. Kitao Y,Ozawa K,Miyazaki M,Tamatani M,Kobayashi T,Yanagi H,Okabe M,Ikawa M,Yamashima T,Stern DM,Hori O,Ogawa S J Clin Invest. 108 10 1439 2001/11
- Antitumor effect of reduction of 150-kDa oxygen-regulated protein expression on human prostate cancer cells T Miyagi,O Hori,K Koshida,M Egawa,H Kato,Y Kitagawa,K Ozawa,S Ogawa,M Namiki INTERNATIONAL JOURNAL OF UROLOGY 9 10 577 2002/10
- The effect of Ndrg2 expression on astroglial activation Toshiaki Takeichi,Mika Takarada-lemata,Koji Hashida,Hirofumi Sudo,Tomohiko Okuda,Koichi Kokame,Taku Hatano,Masashi Takanashi,Sayaka Funabe,Nobutaka Hattori,Osamu Kitamura,Yasuko Kitao,Osamu Hori NEUROCHEMISTRY INTERNATIONAL 59 1 21 2011/08
- A dibenzoylmethane derivative protects H2O2-induced cell death and inhibits lipopolysaccharide- induced NO production in cultured rat astrocytes. Katsura Takano,Kumiko Sugita,Mitsuaki Moriyama,K. Hashida,Satoshi Hibino,Tominari Choshi,Rika Murakami,Masashi Yamada,Hiroto Suzuki,Osamu Hori,Yoichi Nakamura Journal of Neuroscience Research 89 955 2011/03
- Glutamate Preferentially Suppresses Osteoblastogenesis Than Adipogenesis Through the Cystine/Glutamate Antiporter in Mesenchymal Stem Cells Mika Takarada-Iemata,Takeshi Takarada,Yukari Nakamura,Eri Nakatani,Osamu Hori,Yukio Yoneda JOURNAL OF CELLULAR PHYSIOLOGY 226 3 652 2011/03
- Cellular stress responses: Cell survival and cell death Simone Fulda,Adrienne M. Gorman,Osamu Hori,Afshin Samali International Journal of Cell Biology 2010 214074 2010
- Editorial: Cell stress and cell death Afshin Samali,Simone Fulda,Adrienne M. Gorman,Osamu Hori,Srinivasa M. Srinivasula International Journal of Cell Biology 2010 245803 2010
- Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2 Anika E. Wagner,Christine Boesch-Saadatmandi,Dorothea Breckwoldt,Charlotte Schrader,Constance Schmelzer,Frank Doering,Koji Hashida,Osamu Hori,Seiichi Matsugo,Gerald Rimbach BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 11 1 2010/01
- [Analysis of astrocyte-derived stress-related genes]. Hori O Kaibogaku zasshi. Journal of anatomy 84 4 113 2009/12
- RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction Kazuhiro Takuma,Fang Fang,Wensheng Zhang,Shiqiang Yan,Emiko Fukuzaki,Heng Du,Alexander Sosunov,Guy McKhann,Yoko Funatsu,Noritaka Nakamichi,Taku Nagai,Hiroyuki Mizoguchi,Daisuke Ibi,Osamu Hori,Satoshi Ogawa,David M. Stern,Kiyofumi Yamada,Shirley ShiDu Yan PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106 47 20021 2009/11
- A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress Katsura Takano,Yasuko Kitao,Yoshiyuki Tabata,Hikari Miura,Kosuke Sato,Kazuhiro Takuma,Kiyofumi Yamada,Satoshi Hibino,Tominari Choshi,Munekazu Iinuma,Hiroto Suzuki,Rika Murakami,Masashi Yamada,Satoshi Ogawa,Osamu Hori AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 293 6 C1884 2007/12
- Ischemia-induced neuronal cell death and stress response Satoshi Ogawa,Yasuko Kitao,Osamu Hori ANTIOXIDANTS & REDOX SIGNALING 9 5 573 2007/05
- Does ORP150/HSP12A protect dopaminergic neurons against MPTP/MPP+-induced neurotoxicity? Yasuko Kitao,Tomohiro Matsuyama,Katsura Takano,Yoshiyuki Tabata,Tanihiro Yoshimoto,Takashi Momoi,Atsushi Yamatodani,Satoshi Ogawa,Osamu Hori ANTIOXIDANTS & REDOX SIGNALING 9 5 589 2007/05
- Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin Katsura Takano,Yoshiyuki Tabata,Yasuko Kitao,Rika Murakami,Hiroto Suzuki,Masashi Yamada,Munekazu Iinuma,Yukio Yoneda,Satoshi Ogawa,Osamu Hori AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 292 1 C353 2007/01
- [Neuronal cell death and stress response]. Satoshi Ogawa,Osamu Hori Seikagaku. The Journal of Japanese Biochemical Society 78 10 973 2006/10
- The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes K Ozawa,M Miyazaki,M Matsuhisa,K Takano,Y Nakatani,M Hatazaki,T Tamatani,K Yamagata,JI Miyagawa,Y Kitao,O Hori,Y Yamasaki,S Ogawa DIABETES 54 3 657 2005/03
- ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death Y Bando,Y Tsukamoto,T Katayama,K Ozawa,Y Kitao,O Hori,DM Stern,A Yamauchi,S Ogawa FASEB JOURNAL 18 10 1401 2004/07
- ORP150/HSP12A regulates Purkinje cell survival: A role for endoplasmic reticulum stress in cerebellar development Y Kitao,K Hashimoto,T Matsuyama,H Iso,T Tamatani,O Hori,DM Stern,M Kano,K Ozawa,S Ogawa JOURNAL OF NEUROSCIENCE 24 6 1486 2004/02
- Hypoxia/ischemia-induced neuronal death is caused by stress from endoplasmic reticulum M Tohyama,O Hori,S Ogawa JOURNAL OF NEUROCHEMISTRY 87 25 2003/12
- Introduction of MPEG-7 HORI Osamu The Journal of the Institute of Television Engineers of Japan 56 11 1708 2002/11/01
- Forum original research communication - Hypoxia-mediated induction of herne oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis Naohiko Imuta,Osamu Hori,Yasuko Kitao,Yoshiyuki Tabata,Tanihiro Yoshimoto,Tomohiro Matsuyama,Satoshi Ogawa ANTIOXIDANTS & REDOX SIGNALING 9 5 543 2007/05
- Methoxyflavones protect cells against endoplasmic reticulum (ER) stress and neurotoxin. Katsura Takano,Yoshiyuki Tabata,Yasuko Kitao,Rika Murakami,Hiroto Suzuki,Masashi Yamada,Munekazu Iinuma,Yukio Yoneda,Satoshi Ogawa,Osamu Hori YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 127 186 2007
- Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Yasuko Kitao,Yuzuru Imai,Kentaro Ozawa,Ayane Kataoka,Toshio Ikeda,Mariko Soda,Kazuhiko Nakimawa,Hiroshi Kiyama,David M Stern,Osamu Hori,Kazumasa Wakamatsu,Shosuke Ito,Shigeyoshi Itohara,Ryosuke Takahashi,Satoshi Ogawa Human molecular genetics 16 1 50 2007/01/01
- A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies). Katsura Takano,Yasuko Kitao,Reiko Inagi,Takashi Momoi,Tomohiro Matsuyama,Toshio Miyata,Yukio Yoneda,Hiroyuki Iso,David M Stern,Osamu Hori,Satoshi Ogawa Biochemical and biophysical research communications 346 3 1040 2006/08/04
- Role of Herp in the endoplasmic reticulum stress response. Osamu Hori,Fusae Ichinoda,Atsushi Yamaguchi,Takashi Tamatani,Manabu Taniguchi,Yoshihisa Koyama,Taiichi Katayama,Masaya Tohyama,David M Stern,Kentaro Ozawa,Yasuko Kitao,Satoshi Ogawa Genes to cells : devoted to molecular & cellular mechanisms 9 5 457 2004/05
- Plasma Corticosterone Activates SGK1 and Induces Morphological Changes in Oligodendrocytes in Corpus Callosum Shingo Miyata,Yoshihisa Koyama,Kana Takemoto,Keiko Yoshikawa,Toshiko Ishikawa,Manabu Taniguchi,Kiyoshi Inoue,Miwa Aoki,Osamu Hori,Taiichi Katayama,Masaya Tohyama PLOS ONE 6 5 e19859 2011/05
- Efficacy of Dibenzoylmethane Derivatives in Protecting against Endoplasmic Reticulum Stress and Inhibiting Nuclear Factor Kappa B on Dextran Sulfate Sodium Induced Colitis in Mice Rika Murakami,Masayuki Uchida,Osamu Hori,Nobuyasu Matsuura,Tominari Choshi,Satoshi Hibino,Masashi Yamada BIOLOGICAL & PHARMACEUTICAL BULLETIN 33 12 2029 2010/12
- Suppression of Expression of Endoplasmic Reticulum Chaperones by Helicobacter pylori and Its Role in Exacerbation of Non-steroidal Anti-inflammatory Drug-induced Gastric Lesions Takushi Namba,Tatsuya Hoshino,Shintaro Suemasu,Mika Takarada-Iemata,Osamu Hori,Naomi Nakagata,Akinori Yanaka,Tohru Mizushima JOURNAL OF BIOLOGICAL CHEMISTRY 285 48 37302 2010/11
- Deletion of Herp facilitates degradation of cytosolic proteins Hikari Miura,Koji Hashida,Hirofumi Sudo,Yoshitaka Awa,Mika Takarada-Iemata,Koichi Kokame,Tetsuya Takahashi,Masayasu Matsumoto,Yasuko Kitao,Osamu Hori GENES TO CELLS 15 8 843 2010/08
- Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Osamu Hori,Mayuki Miyazaki,Takashi Tamatani,Kentaro Ozawa,Katsura Takano,Masaru Okabe,Masahito Ikawa,Enno Hartmann,Petra Mai,David M Stern,Yasuko Kitao,Satoshi Ogawa Molecular and cellular biology 26 11 4257 2006/06
- Gene therapy for prostate cancer using the cytosine deaminase/uracil phosphoribosyttransferase suicide system T Miyagi,K Koshida,O Hori,H Konaka,H Katoh,Y Kitagawa,A Mizokami,M Egawa,S Ogawa,H Hamada,M Namiki JOURNAL OF GENE MEDICINE 5 1 30 2003/01
- A Carbazole Derivative Protects Cells Against Endoplasmic Reticulum (ER) Stress and Glutathione Depletion Hikari Miura,Katsura Takano,Yasuko Kitao,Satoshi Hibino,Tominari Choshi,Rika Murakami,Hiroto Suzuki,Masashi Yamada,Satoshi Ogawa,Osamu Hori JOURNAL OF PHARMACOLOGICAL SCIENCES 108 2 164 2008/10
- Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction Lee Stanyer,Wenche Jorgensen,Osamu Hori,John B. Clark,Simon J. R. Heales NEUROCHEMISTRY INTERNATIONAL 53 3-4 95 2008/09
- A novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia Shunya Takizaw,Yuko Izuhara,Yasuko Kitao,Osamu Hori,Satoshi Ogawa,Yuko Morita,Shigeharu Takagi,Charles van Ypersele de Strihou,Toshio Miyata BRAIN RESEARCH 1183 124 2007/12
- Vaticanol B, a resveratrol tetramer, regulates endoplasmic reticulum stress and inflammation Yoshiyuki Tabata,Katsura Takano,Tetsuro Ito,Munekazu Iinuma,Tanihiro Yoshimoto,Hikari Miura,Yasuko Kitao,Satoshi Ogawa,Osamu Hori AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 293 1 C411 2007/07
- Antioxidant effects of the hydroxy groups in the simple phenolic carbazoles Yuhzo Hieda,Noriyuki Hatae,Makoto Anraku,Nobuyasu Matsuura,Kazuhide Uemura,Satoshi Hibino,Tominari Choshi,Hisao Tomida,Osamu Hori,Haruto Fujioka Heterocycles 92 1 120 2016
- Atf6 alpha deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis Hieu Minh Ta,Thuong Manh Le,Hiroshi Ishii,Mika Takarada-Iemata,Tsuyoshi Hattori,Koji Hashida,Yasuhiko Yamamoto,Kazutoshi Mori,Ryosuke Takahashi,Yasuko Kitao,Osamu Hori JOURNAL OF NEUROCHEMISTRY 139 6 1124 2016/12
- CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously Tsuyoshi Hattori,Minoru Kaji,Hiroshi Ishii,Roboon Jureepon,Mika Takarada-Iemata,Hieu Minh Ta,Thuong Manh Le,Ayumu Konno,Hirokazu Hirai,Yoshitake Shiraishi,Noriyuki Ozaki,Yasuhiko Yamamoto,Hiroshi Okamoto,Shigeru Yokoyama,Haruhiro Higashida,Yasuko Kitao,Osamu Hori GLIA 65 6 974 2017/06
- Deletion of Atf6 alpha enhances kainate-induced neuronal death in mice Dai Kezuka,Mika Tkarada-Iemata,Tsuyoshi Hattori,Kazutoshi Mori,Ryosuke Takahashi,Yasuko Kitao,Osamu Hori NEUROCHEMISTRY INTERNATIONAL 92 67 2016/01
- Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson's Disease Thuong Manh Le,Koji Hashida,Hieu Minh Ta,Mika Takarada-Iemata,Koichi Kokame,Yasuko Kitao,Osamu Hori PARKINSONS DISEASE 2016 6163934 2016
- Transgenic supplementation of SIRT1 fails to alleviate acute loss of nigrostriatal dopamine neurons and gliosis in a mouse model of MPTP-induced parkinsonism Yasuko Kitao,Natsumi Ageta-Ishihara,Ryosuke Takahashi,Makoto Kinoshita,Osamu Hori F1000Research 4 130 2015/05/27
- Alterations in dendrite and spine morphology of cortical pyramidal neurons in DISC1-binding zinc finger protein (DBZ) knockout mice Yoshihisa Koyama,Tsuyoshi Hattori,Tomoki Nishida,Osamu Hori,Masaya Tohyama FRONTIERS IN NEUROANATOMY 9 52 2015/04
- Deletion of Atf6 alpha impairs astroglial activation and enhances neuronal death following brain ischemia in mice Akifumi Yoshikawa,Tomoya Kamide,Koji Hashida,Hieu Minh Ta,Yuki Inahata,Mika Takarada-Iemata,Tsuyoshi Hattori,Kazutoshi Mori,Ryosuke Takahashi,Tomohiro Matsuyama,Yutaka Hayashi,Yasuko Kitao,Osamu Hori JOURNAL OF NEUROCHEMISTRY 132 3 342 2015/02
- Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease Olga Lopatina,Toru Yoshihara,Tomoko Nishimura,Jing Zhong,Shirin Akther,Azam A. K. M. Fakhrul,Mingkun Liang,Chiharu Higashida,Kohei Sumi,Kazumi Furuhara,Yuki Inahata,Jian-Jung Huang,Keita Koizumi,Shigeru Yokoyama,Takahiro Tsuji,Yulia Petugina,Andrei Sumarokov,Alla B. Salmina,Koji Hashida,Yasuko Kitao,Osamu Hori,Masahide Asano,Yoji Kitamura,Takashi Kozaka,Kazuhiro Shiba,Fangfang Zhong,Min-Jue Xie,Makoto Sato,Katsuhiko Ishihara,Haruhiro Higashida FRONTIERS IN BEHAVIORAL NEUROSCIENCE 8 133 2014/04
- 3,4-Dihydroxybenzalacetone Protects Against Parkinson's Disease-Related Neurotoxin 6-OHDA Through Akt/Nrf2/Glutathione Pathway Kei Gunjima,Ryoichi Tomiyama,Ken Takakura,Takashi Yamada,Koji Hashida,Yutaka Nakamura,Tetsuya Konishi,Seiichi Matsugo,Osamu Hori JOURNAL OF CELLULAR BIOCHEMISTRY 115 1 151 2014/01
- Modeling Alzheimer's Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular A beta and Differential Drug Responsiveness Takayuki Kondo,Masashi Asai,Kayoko Tsukita,Yumiko Kutoku,Yutaka Ohsawa,Yoshihide Sunada,Keiko Imamura,Naohiro Egawa,Naoki Yahata,Keisuke Okita,Kazutoshi Takahashi,Isao Asaka,Takashi Aoi,Akira Watanabe,Kaori Watanabe,Chie Kadoya,Rie Nakano,Dai Watanabe,Kei Maruyama,Osamu Hori,Satoshi Hibino,Tominari Choshi,Tatsutoshi Nakahata,Hiroyuki Hioki,Takeshi Kaneko,Motoko Naitoh,Katsuhiro Yoshikawa,Satoko Yamawaki,Shigehiko Suzuki,Ryuji Hata,Shu-ichi Ueno,Tsuneyoshi Seki,Kazuhiro Kobayashi,Tatsushi Toda,Kazuma Murakami,Kazuhiro Irie,William L. Klein,Hiroshi Mori,Takashi Asada,Ryosuke Takahashi,Nobuhisa Iwata,Shinya Yamanaka,Haruhisa Inoue CELL STEM CELL 12 4 487 2013/04
- Displays of paternal mouse pup retrieval following communicative interaction with maternal mates Hong-Xiang Liu,Olga Lopatina,Chiharu Higashida,Hiroko Fujimoto,Shirin Akther,Alena Inzhutova,Mingkun Liang,Jing Zhong,Takahiro Tsuji,Toru Yoshihara,Kohei Sumi,Mizuho Ishiyama,Wen-Jie Ma,Mitsunori Ozaki,Satoshi Yagitani,Shigeru Yokoyama,Naofumi Mukaida,Takeshi Sakurai,Osamu Hori,Katsuji Yoshioka,Atsushi Hirao,Yukio Kato,Katsuhiko Ishihara,Ichiro Kato,Hiroshi Okamoto,Stanislav M. Cherepanov,Alla B. Salmina,Hirokazu Hirai,Masahide Asano,David A. Brown,Isamu Nagano,Haruhiro Higashida NATURE COMMUNICATIONS 4 1346 2013/01
- Inhibition of nuclear factor-κB p65 phosphorylation by 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester. Takakura K,Takatou S,Tomiyama R,Le TM,Nguyen DT,Nakamura Y,Konishi T,Matsugo S,Hori O Journal of pharmacological sciences 137 3 248 2018/07
- A dibenzoylmethane derivative inhibits lipopolysaccharide-induced NO production in mouse microglial cell line BV-2. Takano K,Ishida N,Kawabe K,Moriyama M,Hibino S,Choshi T,Hori O,Nakamura Y Neurochemistry international 119 126 2018/10
- Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice. Yasuhiko Yamamoto,Mingkun Liang,Seiichi Munesue,Kisaburo Deguchi,Ai Harashima,Kazumi Furuhara,Teruko Yuhi,Jing Zhong,Shirin Akther,Hisanori Goto,Yuya Eguchi,Yasuko Kitao,Osamu Hori,Yoshitake Shiraishi,Noriyuki Ozaki,Yu Shimizu,Tomoya Kamide,Akifumi Yoshikawa,Yasuhiko Hayashi,Mitsutoshi Nakada,Olga Lopatina,Maria Gerasimenko,Yulia Komleva,Natalia Malinovskaya,Alla B Salmina,Masahide Asano,Katsuhiko Nishimori,Steven E Shoelson,Hiroshi Yamamoto,Haruhiro Higashida Communications biology 2 76 76 2019
- Ndrg2 deficiency ameliorates neurodegeneration in experimental autoimmune encephalomyelitis Thuong Manh Le,Mika Takarada-Iemata,Hieu Minh Ta,Jureepon Roboon,Hiroshi Ishii,Takashi Tamatani,Yasuko Kitao,Tsuyoshi Hattori,Osamu Hori Journal of Neurochemistry 145 2 139 2018/04/01
- 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells Ryoichi Tomiyama,Ken Takakura,Shouhei Takatou,Thuong M. Le,Takumi Nishiuchi,Yutaka Nakamura,Tetsuya Konishi,Seiichi Matsugo,Osamu Hori JOURNAL OF CELLULAR PHYSIOLOGY 233 2 1671 2018/02
- The role of Ndrg2 on astroglial activation in stab wound injury model M. Takarada-Iemata,D. Kezuka,T. Takeichi,Y. Kitao,O. Hori JOURNAL OF NEUROCHEMISTRY 125 121 2013/05
- Impairment of endoplasmic reticulum in liver as an early consequence of the systemic inflammatory response in rats Sylvia Nuernberger,Ingrid Miller,J. Catharina Duvigneau,Edel T. Kavanagh,Sanjeev Gupta,Romana T. Hartl,Osamu Hori,Bernd Gesslbauer,Afshin Samali,Andreas Kungl,Heinz Redl,Andrey V. Kozlov AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 303 12 G1373 2012/12
- Association fibers connecting the Broca center and the lateral superior frontal gyrus: a microsurgical and tractographic anatomy Masashi Kinoshita,Harumichi Shinohara,Osamu Hori,Noriyuki Ozaki,Fumiaki Ueda,Mitsutoshi Nakada,Jun-ichiro Hamada,Yutaka Hayashi JOURNAL OF NEUROSURGERY 116 2 323 2012/02
- RAGE mediates vascular injury and inflammation after global cerebral ischemia Tomoya Kamide,Yasuko Kitao,Toshiaki Takeichi,Akiko Okada,Hiromi Mohri,Ann Marie Schmidt,Takayuki Kawano,Seiichi Munesue,Yasuhiko Yamamoto,Hiroshi Yamamoto,Jun-ichiro Hamada,Osamu Hori NEUROCHEMISTRY INTERNATIONAL 60 3 220 2012/02
- alpha-Lipoic acid (LA) enantiomers protect SH-SY5Y cells against glutathione depletion Takashi Yamada,Koji Hashida,Mika Takarada-Iemata,Seiichi Matsugo,Osamu Hori NEUROCHEMISTRY INTERNATIONAL 59 7 1003 2011/12
- Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles Yuhzo Hieda,Makoto Anraku,Tominari Choshi,Hisao Tomida,Haruto Fujioka,Noriyuki Hatae,Osamu Hori,Junzo Hirose,Satoshi Hibino BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 24 15 3530 2014/08
- Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury Mika Takarada-Iemata,Dai Kezuka,Toshiaki Takeichi,Masahito Ikawa,Tsuyoshi Hattori,Yasuko Kitao,Osamu Hori JOURNAL OF NEUROCHEMISTRY 130 3 374 2014/08
- 中枢神経・認知症 内在性分泌型RAGEは脳虚血から神経細胞を保護する 清水 有,山本 靖彦,原島 愛,棟居 聖一,大石 正博,林 康彦,中田 光俊,北尾 康子,堀 修,山本 博 糖尿病合併症 29 Suppl.1 197 2015/11
- Pre-administration of low-dose methamphetamine enhances movement and neural activity after high-dose methamphetamine administration in the striatum. Takeichi T,Hori O,Hattori T,Kiryu K,Zuka M,Kitamura O Neurosci Lett. 703 119 2019/06
- Microglial activation in the cochlear nucleus after early hearing loss in rats. Noda M,Hatano M,Hattori T,Takarada-Iemata M,Shinozaki T,Sugimoto H,Ito M,Yoshizaki T,Hori O Auris Nasus Larynx. 46 5 716 2019/10
- CD38, CD157, and RAGE as Molecular Determinants for Social Behavior. Higashida H,Hashii M,Tanaka Y,Matsukawa S,Higuchi Y,Gabata R,Tsubomoto M,Seishima N,Teramachi M,Kamijima T,Hattori T,Hori O,Tsuji C,Cherepanov SM,Shabalova AA,Gerasimenko M,Minami K,Yokoyama S,Munesue SI,Harashima A,Yamamoto Y,Salmina AB,Lopatina O Cells 9 1 2019/12
- Does the superior fronto-occipital fascicle exist in the human brain? Fiber dissection and brain functional mapping in 90 patients with gliomas Xiaoliang Liu,Masashi Kinoshita,Harumichi Shinohara,Osamu Hori,Noriyuki Ozaki,Mitsutoshi Nakada NeuroImage: Clinical 25 102192 2020
- Neuroprotective Effects of Endogenous Secretory Receptor for Advanced Glycation End-products in Brain Ischemia. Yu Shimizu,Ai Harashima,Seiichi Munesue,Masahiro Oishi,Tsuyoshi Hattori,Osamu Hori,Yasuko Kitao,Hiroshi Yamamoto,Nontaphat Leerach,Mitsutoshi Nakada,Yasuhiko Yamamoto,Yasuhiko Hayashi Aging and disease 11 3 547 2020/05
- Direct evidence of the relationship between brain metastatic adenocarcinoma and white matter fibers: A fiber dissection and diffusion tensor imaging tractography study Xiaoliang Liu,Masashi Kinoshita,Harumichi Shinohara,Osamu Hori,Noriyuki Ozaki,Toshihisa Hatta,Satoru Honma,Mitsutoshi Nakada Journal of Clinical Neuroscience 77 55 2020/07
- Astrocytes in the pathogenesis of multiple sclerosis Mika Takarada-Iemata,Osamu Hori Folia Pharmacologica Japonica 156 4 230 2021
- RAGE signaling antagonist suppresses mouse macrophage foam cell formation. Nontaphat Leerach,Seiichi Munesue,Ai Harashima,Kumi Kimura,Yu Oshima,Shuhei Kawano,Mariko Tanaka,Akane Niimura,Natthiya Sakulsak,Hiroshi Yamamoto,Osamu Hori,Yasuhiko Yamamoto Biochemical and biophysical research communications 555 74 2021/05/28
- Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD. Jureepon Roboon,Tsuyoshi Hattori,Hiroshi Ishii,Mika Takarada-Iemata,Dinh Thi Nguyen,Collin D Heer,Denis O'Meally,Charles Brenner,Yasuhiko Yamamoto,Hiroshi Okamoto,Haruhiro Higashida,Osamu Hori Journal of neurochemistry 158 2 311 2021/07
- Pyramid-Shape Crossings and Intercrossing Fibers Are Key Elements for Construction of the Neural Network in the Superficial White Matter of the Human Cerebrum Harumichi Shinohara,Xiaoliang Liu,Riho Nakajima,Masashi Kinoshita,Noriyuki Ozaki,Osamu Hori,Mitsutoshi Nakada Cerebral Cortex 30 10 5218 2020/09/03
- [Astrocytes in the pathogenesis of multiple sclerosis]. Mika Takarada-Iemata,Osamu Hori Nihon yakurigaku zasshi. Folia pharmacologica Japonica 156 4 230 2021
- Displays of paternal mouse pup retrieval following communicative interaction with maternal mates Liu HX, Lopatina O, Higashida C, Fujimoto H, Akther S, Inzhutova A, Liang M, Zhong J, Tsuji T, Yoshihara T, Sumi K, Ishiyama M, Ma WJ, Ozaki M, Yagitani S, Yokoyama S, Mukaida N, Sakurai T, Hori O, Yoshioka K, Hirao A, Kato Y, Ishihara K, Kato I, Okamoto H, Cherepanov SM, Salmina AB, Hirai H, Asano M, Brown DA, Nagano I, Higashida H Nat Commun 2013
- Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H. Cell Stem Cell 2013
- 3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway Gunjima K, Tomiyama R, Takakura K, Yamada T, Hashida K, Nakamura Y, Konishi T, Matsugo S, Hori O J Cell Biochem 2014
- Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease Lopatina O, Yoshihara T, Nishimura T, Zhong J, Akther S, Fakhrul AA, Liang M, Higashida C, Sumi K, Furuhara K, Inahata Y, Huang JJ, Koizumi K, Yokoyama S, Tsuji T, Petugina Y, Sumarokov A, Salmina AB, Hashida K, Kitao Y, Hori O, Asano M, Kitamura Y, Kozaka T, Shiba K, Zhong F, Xie MJ, Sato M, Ishihara K, Higashida H Front Behav Neurosci 2014
- Alterations in dendrite and spine morphology of cortical pyramidal neurons in DISC1-binding zinc finger protein (DBZ) knockout mice Koyama Y, Hattori T, Nishida T, Hori O, Tohyama M Front Neuroanat 2015
- Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson's Disease Le TM, Hashida K, Ta HM, Takarada-Iemata M, Kokame K, Kitao Y, Hori O. Parkinsons Disease 2016
- Transgenic supplementation of SIRT1 fails to alleviate acute loss of nigrostriatal dopamine neurons and gliosis in a mouse model of MPTP-induced parkinsonism Kitao Y, Ageta-Ishihara N, Takahashi R, Kinoshita M, Hori O F1000Research 2015
- Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury Takarada-Iemata, Mika; Kezuka, Dai; Takeichi, Toshiaki; Ikawa, Masahito; Hattori, Tsuyoshi; Kitao, Yasuko; Hori, Osamu Journal of Neurochemistry 130 3 374-387 2014/01/01
- ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson's Disease Hashida, Koji; Kitao, Yasuko; Sudo, Hirofumi; Awa, Yoshitaka; Maeda, Shinichiro; Mori, Kazutoshi; Takahashi, Ryosuke; Iinuma, Munekazu; Hori, Osamu PLoS ONE 7 10 2012/10/24
- Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles Hieda, Yuhzo; Anraku, Makoto; Choshi, Tominari; Tomida, Hisao; Fujioka, Haruto; Hatae, Noriyuki; Hori, Osamu; Hirose, Junzo; Hibino, Satoshi Bioorganic and Medicinal Chemistry Letters 24 15 3530-3533 2014/08/01
- Plasma Corticosterone Activates SGK1 and Induces Morphological Changes in Oligodendrocytes in Corpus Callosum Miyata, Shingo;Koyama, Yoshihisa;Takemoto, Kana;Yoshikawa, Keiko;Ishikawa, Toshiko;Taniguchi, Manabu;Inoue, Kiyoshi;Aoki, Miwa;Hori, Osamu;Katayama, Taiichi;Tohyama, Masaya PLOS ONE 6 5 0-0 2011
- RAGE mediates vascular injury and inflammation after global cerebral ischemia Kamide, Tomoya; Kitao, Yasuko; Takeichi, Toshiaki; Okada, Akiko; Mohri, Hiromi; Schmidt, Ann Marie; Kawano, Takayuki; Munesue, Seiichi; Yamamoto, Yasuhiko; Yamamoto, Hiroshi; Hamada, Junichiro; Hori, Osamu Neurochemistry International 60 3 220-228 2012/02/01
- The effect of Ndrg2 expression on astroglial activation Takeichi, Toshiaki; Takarada-Iemata, Mika; Hashida, Koji; Sudo, Hirofumi; Okuda, Tomohiko; Kokame, Koichi; Hatano, Taku; Takanashi, Masashi; Funabe, Sayaka; Hattori, Nobutaka; Kitamura, Osamu; Kitao, Yasuko; Hori, Osamu Neurochemistry International 59 1 21-27 2011/08/01
- The effects of dibenzoylmethane derivatives on the function of cultured astrocytes Takano, Katsura;Sugita, Kumiko;Moriyama, Mitsuaki;Hashida, Koji;Hibino, Satoshi;Choshi, Tominari;Murakami, Rika;Yamada, Masashi;Suzuki, Hiroto;Hori, Osamu;Nakamura, Yoichi JOURNAL OF PHARMACOLOGICAL SCIENCES 115 0 187P-187P 2011
- Glutamate Preferentially Suppresses Osteoblastogenesis Than Adipogenesis Through the Cystine/Glutamate Antiporter in Mesenchymal Stem Cells Takarada-Iemata, Mika;Takarada, Takeshi;Nakamura, Yukari;Nakatani, Eri;Hori, Osamu;Yoneda, Yukio JOURNAL OF CELLULAR PHYSIOLOGY 226 3 652-665 2011
Conference Presentations
Others
- A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies). 2006
- Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. 16 1 50-60 2007
- Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis. 9, 543-552 2007
- Ischemia-induced neuronal cell death and stress response. 9 573-587 2007
- novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia. 2007
- A Carbazole Derivative Protects Cells Against Endoplasmic Reticulum (ER) Stress and Glutathione Depletion. 108 2,164-71 2008
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「小胞体内レドックス異常により誘導される神経細胞死とその制御」(2007-)
○「小胞体関連分解(ERAD)制御によるタンパク分解ストレスの軽減と細胞保護」(2008-)
○「ATF6による黒質神経細胞の救済と蛋白質凝集抑制」(2011-2013)
Competitive research funding,Contribution
Collaborative research,Consignment study
○Analysis of gene network in Parkinson Disease(2007-2012)
Classes (Bachelors)
○Neuroanatomy(2017)
○Practical Medical Research(2017)
○Extended Exercise for Basic Medical Sciences(2017)
○Embryology(2017)
○Basic Health Science(2017)
○Extended Exercise for Basic Medical Sciences(2016)
○Presentation and Debate (Freshman Seminar II)(2016)
○Freshman Seminar I(2016)
○Basic Health Science(2016)
○Neuroanatomy(2016)
○Human Embryology(2016)
Classes (Graduate Schools)
○Seminar on Up-to-Date(2017)
○Molecular Targeting in the Central Nervous System(2017)
○Environmental Science Up-To-Date(2017)
○Recent Advance in Medicine(2017)
○Recent Advance in Cardiovascular Medicine(2017)
○Molecular Targeting in the Central Nervous System(2017)
○Recent Advance in Medicine(2017)
○Presentation(2017)
○Presentation(2017)
○Recent Advance in Cancer Medicine(2017)
○Recent Advance in Neuroscience(2017)
○Seminar on Up-to-Date(2017)
○Recent Advance in Environmental Science(2017)
○Cardiovascular Medicine Up-To-Date(2017)
○Neuroscience Up-To-Date(2017)
○Cancer Medicine Up-Todate(2017)
○Molecular Targeting in the Central Nervous System(2017)
○Principles of Anatomy(2017)
○Medical Sciences(2016)
○Recent Advance in Neuroscience(2016)
○Molecular Targeting in the Central Nervous System(2016)
○Recent Advance in Medicine(2016)
○Principles of Anatomy(2016)
○Seminar on Up-to-Date(2016)
○Molecular Targeting in the Central Nervous System(2016)
○Cancer Medicine Up-Todate(2016)
○Neuroscience Up-To-Date(2016)
○Recent Advance in Medicine(2016)
○Presentation(2016)
○Presentation(2016)
○Molecular Targeting in the Central Nervous System(2016)
○Recent Advance in Cancer Medicine(2016)
○Environmental Science Up-To-Date(2016)
○Recent Advance in Cardiovascular Medicine(2016)
○Cardiovascular Medicine Up-To-Date(2016)
○Recent Advance in Environmental Science(2016)
○Seminar on Up-to-Date(2016)