Assistant Professor KAWAHARA, Hironori
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences immunology
College and School Educational Field
Laboratory
immunology TEL:076-265-2727 FAX:076-265-2734
Academic Background
【Academic background(Doctoral/Master's Degree)】
Keio University School of Medicine Doctor Graduate School of Medicine Physiology
Career
Osaka University IFReC Postdoctoral Research Fellow
University of Pennsylvania Cell & Developmental Biology Perelman School of Medicine Postdoctoral Fellow
Keio University School of Medicine School of Medicine
Year & Month of Birth
Academic Society
Award
Specialities
Neuroimmunology, RNA Biology, Developmental Biology
Speciality Keywords
Exosome, Neuroimmunology, RNA Biology, Neural Stem Cell
Research Themes
Books
Papers
- Extracellular vesicles contribute to the metabolism of transthyretin amyloid in hereditary transthyretin amyloidosis Hiroki Yamaguchi, Hironori Kawahara, Noriyuki Kodera, Ayanori Kumaki, Yasutake Tada, Zixin Tang, Kenji Sakai, Kenjiro Ono, Masahito Yamada, Rikinari Hanayama Frontiers in Molecular Biosciences 9 839917 2022
- Tumor-secreted proliferin-1 regulates adipogenesis and lipolysis in cachexia. Tuan Duc Nguyen, Yuji Miyatake, Takeshi Yoshida, Hironori Kawahara, Rikinari Hanayama. Int J Cancer 15 148 1982-1992 2021
- Glioma-derived extracellular vesicles promote tumor progression by conveying WT1. Taishi Tsutsui, Hironori Kawahara, Ryouken Kimura, Yu Dong, Shabierjiang Jiapaer, Hemragul Sabit, Jiakang Zhang, Takeshi Yoshida, Mitsutoshi Nakada, Rikinari Hanayama Carcinogenesis 41 9 1238-1245 2020
- The Role of Exosomes/Extracellular Vesicles in Neural Signal Transduction. Kawahara H, Hanayama R. Biological & pharmaceutical bulletin 41 8 1119-1125 2018
- Behavior of Neuronal Exosomes in Synaptic Communication Hironori Kawahara, Rie Nakatani, Taishi Tsutsui, Sunao Haitani, Shunsuke Kishimoto, Rikinari Hanayama RMRJ 48 1 24-29 2017/01/10
- Characterization of the RNA-binding protein Musashi1 in zebrafish. Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. Brain Res. 1462 162-73 2012
- MicroRNAs in Neural Stem Cells and Neurogenesis. Kawahara H, Imai T, Okano H. Front Neurosci. 6 30 2012
- Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H. J Biol Chem. 286 18 16121-30 2011
- Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. J Cell Biol. 184 4 639-53 2008
- Function of RNA-binding protein Musashi-1 in stem cells. Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Exp Cell Res. 306 2 349-56 2005
Conference Presentations
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○Grant-in-Aid for Young Scientists (B)「RNA-binding protein Musashi1-mediated miRNA regulation」(2009-2010)
○Grant-in-Aid for Research Activity start-up「神経系exosomeに内包する新規レビー小体認知症関連ncRNAの同定と機能解明」(2013-2015)
○Grant-in-Aid for Scientific Research (C)「パーキンソン病原因遺伝子SNCAのexosomeを介した伝播分子制御機構の解明」(2015-2018)