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last modified:2025/03/21
Associate Professor MIZUSHIMA, Ichiro
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University Hospital
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Laboratory
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- Kidney lesions and risk of cardiovascular events in biopsy-proven diabetic kidney disease with type 2 diabetes. Shimizu M, Furuichi K, Toyama T, Yamanouchi M, Hayashi D, Koshino A, Sako K, Horikoshi K, Yuasa T, Tamai A, Minami T, Oshima M, Nakagawa S, Kitajima S, Mizushima I, Hara A, Sakai N, Kitagawa K, Yoshimura M, Hoshino J, Ubara Y, Iwata Y, Wada T. Clin Exp Nephrol. 2025 Mar;29(3):376-386. doi: 29 3 376-386 2025/03/01
- Identification of circulating microbial DNA and its association with kidney function in patients with diabetic kidney disease. Linh HT, Oshima M, Sako K, Konishi M, Hayashi D, Sanada H, Yuasa T, Koshino A, Horikoshi K, Minami T, Tsuge S, Tamai A, Nakagawa S, Nishioka R, Zoshima T, Ito K, Mizushima I, Toyama T, Sakai N, Kitajima S, Shimizu M, Wada T, Iwata Y. Nephrology (Carlton). 2024 Dec;29(12):909-916. doi: 29 12 909-916 2024/12/01
- Effects of d-alanine Intake on Amino Acid Metabolism and Kidney Function in Healthy Adults: A Multicenter, Randomized Pilot Study. Oshima M, Toyama T, Toyama T, Nakade Y, Tokumaru T, Sako K, Kajikawa S, Hayashi D, Sanada H, Yuasa T, Koshino A, Horikoshi K, Minami T, Tsuge S, Tamai A, Nakagawa S, Nishioka R, Zoshima T, Ito K, Kitajima S, Mizushima I, Hara A, Sakai N, Shimizu M, Mita M, Iwata Y, Wada T. Curr Dev Nutr. 8 7 103787 2024/05/23
- Asymmetrical Damage of the Wrist Joint Induces Lateralized Cortical Bone Loss in the Metacarpal Diaphysis in Patients with Rheumatoid Arthritis. Nakashima A, Fujii H, Kuroda M, Zoshima T, Mizushima I, Nomura H, Kawano M. J Clin Med. 2024 Dec 16;13(24):7652. doi: 13 24 7652 2024/12/16
- Factors related to elevated serum immunoglobulin G4 (IgG4) levels in a Japanese general population. Tsuge S, Fujii H, Tamai M, Tsujiguchi H, Yoshida M, Suzuki N, Takahashi Y, Takeji A, Horita S, Fujisawa Y, Matsunaga T, Zoshima T, Nishioka R, Nuka H, Hara S, Tani Y, Suzuki Y, Ito K, Yamada K, Nakazaki S, Hara A, Kawakami A, Nakamura H, Mizushima I, Iwata Y, Kawano M. Arthritis Res Ther. 26 1 156 2024/09/06
- Effects of Corticosteroid Treatment on Olfactory Dysfunction in LATY136F Knock-In Mice. Ozaki F, Ueno T, Kondo S, Kaneda M, Mizushima I, Yamada K, Malissen M, Malissen B, Kawano M, Yoshizaki T. Cureus. 16 7 e65791 2024/06/30
- Validation of the Diagnostic Criteria for IgG4-Related Periaortitis/Periarteritis and Retroperitoneal Fibrosis (IgG4PA/RPF) 2018, and Proposal of a Revised 2023 Version for IgG4-Related Cardiovascular/Retroperitoneal Disease. Mizushima I, Morikage N, Ito E, Kasashima F, Matsumoto Y, Sawa N, Yoshifuji H, Saeki T, Shintani-Domoto Y, Shimada S, Takayama T, Amiya E, Ozawa M, Takahashi M, Fujinaga Y, Katsumata T, Obitsu Y, Izawa A, Kanno H, Oyama-Manabe N, Ishizaka N, Nagasawa T, Takahashi H, Ohki T, Kawano M, Kasashima S; Joint Working Group from the Japanese Circulation Society and the Ministry of Health, Labour and Welfare Study Group. Circulation Journal. 88 10 1679-1688 2024/09/25
- Long-term outcomes of lupus nephritis with low-level proteinuria: a multicentre, retrospective study. Zoshima T, Hara S, Suzuki K, Yoshida M, Konishi M, Hibino S, Suda T, Hoshiba R, Kawahara H, Horita S, Nuka H, Mizushima I, Kawano M. Rheumatology (Oxford). 63 11 3074-3079 2024/11/01
- Solitary recurrence of IgG4-related giant coronary aneurysm: Case report and review of the literature focusing on treatment strategies and complications. Kawahara H, Mizushima I, Matsumoto Y, Sakata K, Takamura M, Inoue D, Kasashima S, Kawano M. Mod Rheumatol Case Rep. 8 1 182-194 2023/12/29
- High serum IgA levels in patients with IgG4-related disease are associated with mild inflammation, sufficient disease-specific features, and favourable responses to treatments. Tsuge S, Mizushima I, Horita M, Kawahara H, Sanada H, Yoshida M, Takahashi Y, Zoshima T, Nishioka R, Hara S, Suzuki Y, Ito K, Kawano M. Modern Rheumatology. 34 3 621-631 2024/03/28
- Pediatric IgG4-related disease: a descriptive review. Hara S, Yoshida M, Sanada H, Suzuki Y, Sato Y, Mizushima I, Kawano M. Expert Rev Clin Immunol. 20 1 97-119 2024/06/01
- Nephrolithiasis and/or nephrocalcinosis is significantly related to renal dysfunction in patients with primary Sjögren's syndrome. Fujisawa Y, Mizushima I, Suzuki Y, Kawano M. Modern Rheumatology. 34 2 376-381 2024/02/26
- Improved renal function in initial treatment improves patient survival, renal outcomes, and glucocorticoid-related complications in IgG4-related kidney disease in Japan Mizushima I, Saeki T, Kobayashi D, Sawa N, Hayashi H, Taniguchi Y, Nakata H, Yamada K, Matsui S, Yasuno T, Masutani K, Nagasawa T, Takahashi H, Ubara Y, Yanagita M, Kawano M Kidney Int Rep 9 1 52-63 2023/10/20
- Clues to mortality trends and their related factors in IgG4-related disease: A Japanese single-center study Kawahara H*, Mizushima I*, Tsuge S, Shin S, Yoshinobu T, Hoshiba R, Nishioka R, Zoshima T, Hara S, Ito K, Kawano M Mod Rheumatol 33 6 1154-1161 2023/11/01
- The differential diagnosis of IgG4-related disease based on machine learning Yamamoto M, Nojima M, Kamekura R, Kuribara-Souta A, Uehara M, Yamazaki H, Yoshikawa N, Aochi S, Mizushima I, Watanabe T, Komai T, Shoda H, Kitagori K, Yoshifuji H, Hamano H, Kawano M, Takano K, Fujio K, Tanaka H Arthritis Res Ther 24 1 71 2022
- Renal Involvement in Retroperitoneal Fibrosis: Prevalence, Impact and Management Challenges Ichiro Mizushima, Mitsuhiro Kawano Int J Nephrol Renovasc Dis 14 279-289 2021
- Serum IgG4 levels at diagnosis can predict unfavorable outcomes of untreated patients with IgG4-related disease. Ichiro Mizushima, Masahiro Konishi, Hajime Sanada, Kazuyuki Suzuki, Akari Takeji, Takeshi Zoshima, Satoshi Hara, Kiyoaki Ito, Hiroshi Fujii, Kazunori Yamada, Mitsuhiro Kawano Scientific Reports 11 1 13341 2021
- Factors contributing to discrepant estimated glomerular filtration values measured by creatinine and cystatin C in patients with rheumatoid arthritis. Akikatsu Nakashima, Shigeto Horita, Takahiro Matsunaga, Ryo Inoue, Takeshi Zoshima, Ichiro Mizushima, Satoshi Hara, Kiyoaki Ito, Hiroshi Fujii, Hideki Nomura, Mitsuhiro Kawano Scientific Reports 11 1 9884 2021
- Glomerulonephritis with severe nephrotic syndrome induced by immune complexes composed of galactose-deficient IgA1 in primary Sjögren's syndrome: a case report Ryo Nishioka, Satoshi Hara, Hiroyuki Kawahara, Kiyoaki Ito, Ichiro Mizushima, Masayoshi Hirata, Michio Nagata, Mitsuhiro Kawano BMC Nephrol 22 1 108 2021
- Pneumonia and central nervous system infection caused by reactivation of varicella-zoster virus in a living-donor kidney transplantation patient: case report and review of the literature Yoshinori Takahashi, Satoshi Hara, Ryohei Hoshiba, Shinya Hibino, Kiyoaki Ito, Takeshi Zoshima, Yasunori Suzuki, Dai Inoue, Ichiro Mizushima, Hiroshi Fujii, Mitsuhiro Kawano CEN Case Rep 10 3 370-377 2021
- Involvement of two or more sets of lacrimal glands and/or major salivary glands is related to greater systemic disease activity due to multi-organ involvement in IgG4-related dacryoadenitis/sialadenitis Yoshinori Takahashi, Ichiro Mizushima, Masahiro Konishi, Hiroyuki Kawahara, Hajime Sanada, Kazuyuki Suzuki, Akari Takeji, Satoshi Hara, Kiyoaki Ito, Hiroshi Fujii, Mitsuhiro Kawano Modern Rheumatology 31 6 1164-1170 2021
- Positive disease-specific autoantibodies have limited clinical significance in diagnosing IgG4-related disease in daily clinical practice. Ichiro Mizushima, Takahiro Yamano, Hiroyuki Kawahara, Shinya Hibino, Ryo Nishioka, Takeshi Zoshima, Satoshi Hara, Kiyoaki Ito, Hiroshi Fujii, Hideki Nomura, Mitsuhiro Kawano Rheumatology (Oxford) 60 7 3317-3325 2021
- Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific? Onoe T, Hara S, Yamada K, Zoshima T, Mizushima I, Ito K, Mori T, Daimon S, Muramoto H, Shimizu M, Iguchi A, Kuma A, Ubara Y, Mitobe M, Tsuruta H, Kishimoto N, Imura J, Konoshita T, Kawano M. BMC Nephrol 22 1 1 2021/01/04
- Tertiary lymphoid tissue in early-stage IgG4-related tubulointerstitial nephritis incidentally detected with a tumor lesion of the ureteropelvic junction Miyanaga T, Mizuguchi K, Hara S, Zoshima T, Inoue D, Nishioka R, Mizushima I, Ito K, Fuji H, Yamada K, Sato Y, Yanagita M, Kawano M BMC Nephrol 22 1 34 2021/01/19
- Fulminant myocarditis and pulmonary cavity lesion induced by disseminated mucormycosis in a chronic hemodialysis patient: Report of an autopsied case. Fujisawa Y, Hara S, Zoshima T, Maekawa N, Inoue D, Sasaki M, Gamou T, Nagata Y, Hayashi K, Takeji A, Ito K, Mizushima I, Fujii H, Kawano M Pathol Int 70 8 557-562 2020/08/01
- Hypocomplementemia is related to elevated serum levels of IgG subclasses other than IgG4 in IgG4-related kidney disease Fujisawa Y*, Mizushima I*, Yamada K, Yamamoto M, Saeki T, Matsui S, Tsuge S, Hara S, Ito K, Fujii H, Takahashi H, Nomura H, Kawa S, and Kawano M Mod Rheumatol 31 1 241-248 2021/01/01
- ANCA-associated nephritis without crescent formation has atypical clinicopathological features; a multicenter retrospective study Zoshima T, Suzuki K, Suzuki F, Hara S, Mizuguchi K, Ito K, Mizushima I, Fujii H, Nomura H, Kawano M Clin Exp Nephrol 24 11 999-1006 2020/11/01
- Wire-loop lesion is associated with serological immune abnormality, but not renal prognosis, in lupus nephritis. Zoshima T, Hara S, Mizushima I, Nishioka R, Ito K, Fujii H, Yamada K, Nomura H, Kawano M Lupus 29 4 407-412. 2020/04/01