last modified：2025/12/05
Associate Professor YAMANO Tomoyoshi
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences 免疫学
College and School Educational Field
School of Medicine, College of Medical, Pharmaceutical and Health Sciences
Laboratory
HANAYAMA Lablatory
Academic Background
【Academic background(Doctoral/Master's Degree)】
Tokyo university of science Doctor
Career
Kanazawa University Department of Immunology Assistant Professor(2017/11-2022/07)
University hosipital of Zurich(2011/04/01-2011/09/30)
University of Munich Institute for Immunology Posdoc(2011/10/01-2017/10/31)
Year & Month of Birth
1981/11
Academic Society
Award
Specialities
Speciality Keywords
Research Themes
Books
Papers
- Direct delivery of immune modulators to tumour-infiltrating lymphocytes using engineered extracellular vesicles. Xiabing Lyu,Tomoyoshi Yamano,Kanto Nagamori,Shota Imai,Toan Van Le,Dilireba Bolidong,Makie Ueda,Shota Warashina,Hidefumi Mukai,Seigo Hayashi,Kazutaka Matoba,Taito Nishino,Rikinari Hanayama Journal of extracellular vesicles 14 4 e70035 2025/04
- Surface-engineered extracellular vesicles to modulate antigen-specific T cell expansion for cancer immunotherapy Xiabing Lyu,Tomoyoshi Yamano,Shota Imai,Toan Van Le,Dilireba Bolidong,Makie Ueda,Shota Warashina,Hidefumi Mukai,Seigo Hayashi,Kazutaka Matoba,Taito Nishino,Rikinari Hanayama bioRxiv 2023/09
- TurboID-EV: Proteomic Mapping of Recipient Cellular Proteins Proximal to Small Extracellular Vesicles. Yuka Li,Eisuke Kanao,Tomoyoshi Yamano,Yasushi Ishihama,Koshi Imami Analytical chemistry 2023/09/14
- Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes. Xiabing Lyu,Shota Imai,Tomoyoshi Yamano,Rikinari Hanayama Pharmaceutical research 40 4 927 2022/09/26
- NIR Bioimaging: Development of Liposome-Encapsulated, Rare-Earth-Doped Y2O3 Nanoparticles as Fluorescent Probes Kohei Soga,Kimikazu Tokuzen,Kosuke Tsuji,Tomoyoshi Yamano,Hiroshi Hyodo,Hidehiro Kishimoto EUROPEAN JOURNAL OF INORGANIC CHEMISTRY 18 18 2673 2010/06
- Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia Hirofumi Okada,Chiaki Nakanishi,Shohei Yoshida,Masaya Shimojima,Junichiro Yokawa,Masayuki Mori,Hayato Tada,Tsuyoshi Yoshimuta,Kenshi Hayashi,Tomoyoshi Yamano,Rikinari Hanayama,Masakazu Yamagishi,Masa-aki Kawashiri Scientific Reports 9 1 4695 2019/12
- B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus - a step towards immune evasion? Yamano T,Steinert M,Steer B,Klein L,Hammerschmidt W,Adler H European journal of immunology 2018/11
- Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen Yasuhiro Mouri,Yoshihiro Ueda,Tomoyoshi Yamano,Minoru Matsumoto,Koichi Tsuneyama,Tatsuo Kinashi,Mitsuru Matsumoto JOURNAL OF IMMUNOLOGY 199 12 3959 2017/12
- Thymic B cells and central T cell tolerance Tomoyoshi Yamano,Madlen Steinert,Ludger Klein FRONTIERS IN IMMUNOLOGY 6 376 2015/07
- Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction Tomoyoshi Yamano,Jelena Nedjic,Maria Hinterberger,Madlen Steinert,Sandra Koser,Sheena Pinto,Norbert Gerdes,Esther Lutgens,Naozumi Ishimaru,Meinrad Busslinger,Benedikt Brors,Bruno Kyewski,Ludger Klein IMMUNITY 42 6 1048 2015/06
- Er3+ -Doped Y2O3 Nanophosphors for Near-Infrared Fluorescence Bioimaging Applications Nallusamy Venkatachalam,Tomoyoshi Yamano,Eva Hemmer,Hiroshi Hyodo,Hidehiro Kishimoto,Kohei Soga JOURNAL OF THE AMERICAN CERAMIC SOCIETY 96 9 2759 2013/09
- Cytotoxic aspects of gadolinium oxide nanostructures for up-conversion and NIR bioimaging Eva Hemmer,Tomoyoshi Yamano,Hidehiro Kishimoto,Nallusamy Venkatachalam,Hiroshi Hyodo,Kohei Soga Acta Biomaterialia 9 1 4734 2013/01
- Synthesis and toxicity assay of ceramic nanophosphors for bioimaging with near-infrared excitation Nallusamy Venkatachalam,Eva Hemmer,Tomoyoshi Yamano,Hiroshi Hyodo,Hidehiro Kishimoto,Kohei Soga PROGRESS IN CRYSTAL GROWTH AND CHARACTERIZATION OF MATERIALS 58 2-3 121 2012
- Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM. Keesiang Lim,Goro Nishide,Elma Sakinatus Sajidah,Tomoyoshi Yamano,Yujia Qiu,Takeshi Yoshida,Akiko Kobayashi,Masaharu Hazawa,Toshio Ando,Rikinari Hanayama,Richard W Wong Nano letters 23 2 619 2023/01/15
- Selective expansion and differentiation of antigen-specific CD4+ T-helper cells by engineered extracellular vesicles. Ryouken Kimura,Tomoyoshi Yamano,Uryo Onishi,Xiabing Lyu,Kanto Nagamori,Toan Van Le,Mitsutoshi Nakada,Rikinari Hanayama Drug delivery 32 1 2509969 2025/12
- Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts Tomoyoshi Yamano,Sho Watanabe,Hiroyuki Hasegawa,Toshihiro Suzuki,Ryo Abe,Hideaki Tahara,Takeshi Nitta,Naozumi Ishimaru,Jonathan Sprent,Hidehiro Kishimoto BLOOD 117 9 2640 2011/03
- Gadolinium-containing inorganic nanostructures for biomedical applications: Cytotoxic aspects Eva Hemmer,Tomoyoshi Yamano,Hidehiro Kishimoto,Kohei Soga ICONN 2010 - Proceedings of the 2010 International Conference on Nanoscience and Nanotechnology 2010 225 2010
- In vitro and in vivo investigations of upconversion and NIR emitting Gd2O3:Er3+,Yb3+ nanostructures for biomedical applications Eva Hemmer,Hiroyuki Takeshita,Tomoyoshi Yamano,Takanori Fujiki,Yvonne Kohl,Karin Loew,Nallusamy Venkatachalam,Hiroshi Hyodo,Hidehiro Kishimoto,Kohei Soga JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 23 10 2399 2012/10
- Dual inhibition of SUMOylation and MEK conquers MYC-expressing KRAS-mutant cancers by accumulating DNA damage. Hiroshi Kotani,Hiroko Oshima,Justin C Boucher,Tomoyoshi Yamano,Hiroyuki Sakaguchi,Shigeki Sato,Koji Fukuda,Akihiro Nishiyama,Kaname Yamashita,Koushiro Ohtsubo,Shinji Takeuchi,Takumi Nishiuchi,Masanobu Oshima,Marco L Davila,Seiji Yano Journal of biomedical science 31 1 68 2024/07/11
- MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C Arisa Hori,Saori Toyoura,Miyu Fujiwara,Ren Taniguchi,Yasutaka Kano,Tomoyoshi Yamano,Rikinari Hanayama,Masafumi Nakayama iScience 27 5 109704 2024/05
- Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes. Miyatake Y,Yamano T,Hanayama R Journal of immunology (Baltimore, Md. : 1950) 201 10 3051 2018/10
- Aire-expressing ILC3-like cells in the lymph node display potent APC features. Yamano T,Dobeš J,Vobořil M,Steinert M,Brabec T,Ziętara N,Dobešová M,Ohnmacht C,Laan M,Peterson P,Benes V,Sedláček R,Hanayama R,Kolář M,Klein L,Filipp D The Journal of experimental medicine 216 5 1027 2019/03
- Comprehensive antitumor immune response boosted by dual inhibition of SUMOylation and MEK in MYC-expressing KRAS-mutant cancers. Hiroshi Kotani,Tomoyoshi Yamano,Justin C Boucher,Shigeki Sato,Hiroyuki Sakaguchi,Koji Fukuda,Akihiro Nishiyama,Kaname Yamashita,Koushiro Ohtsubo,Shinji Takeuchi,Takumi Nishiuchi,Hiroko Oshima,Masanobu Oshima,Marco L Davila,Seiji Yano Experimental hematology & oncology 13 1 94 2024/09/27
- Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM. Elma Sakinatus Sajidah,Keesiang Lim,Tomoyoshi Yamano,Goro Nishide,Yujia Qiu,Takeshi Yoshida,Hanbo Wang,Akiko Kobayashi,Masaharu Hazawa,Firli R P Dewi,Rikinari Hanayama,Toshio Ando,Richard W Wong Journal of extracellular vesicles 11 11 e12275 2022/11
- Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer. Rong Wang,Tadaaki Yamada,Kenji Kita,Hirokazu Taniguchi,Sachiko Arai,Koji Fukuda,Minoru Terashima,Akihiko Ishimura,Akihiro Nishiyama,Azusa Tanimoto,Shinji Takeuchi,Koshiro Ohtsubo,Kaname Yamashita,Tomoyoshi Yamano,Akihiro Yoshimura,Koichi Takayama,Kyoichi Kaira,Yoshihiko Taniguchi,Shinji Atagi,Hisanori Uehara,Rikinari Hanayama,Isao Matsumoto,Xujun Han,Kunio Matsumoto,Wei Wang,Takeshi Suzuki,Seiji Yano Nature communications 11 1 4607 2020/09/14
- Synthesis and toxicity assay of ceramic nanophosphors for bioimaging with near-infrared excitation Venkatachalam N, Hemmer E, Yamano T, Hyodo H, Kishimoto H, Soga K Progress in Crystal Growth and Characterization of Materials 58 2 121-134 2012/06/01
- In vitro and in vivo investigations of upconversion and NIR emitting Gd?O?:Er??,Yb?? nanostructures for biomedical applications. Hemmer E, Takeshita H, Yamano T, Fujiki T, Kohl Y, L?w K, Venkatachalam N, Hyodo H, Kishimoto H, Soga K Journal of materials science. Materials in medicine 23 10 2399-2412 2012/05/01
- Thymic B Cells and Central T Cell Tolerance. Yamano T, Steinert M, Klein L Frontiers in immunology 6 376 2015/07/22
- Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. Yamano T, Nedjic J, Hinterberger M, Steinert M, Koser S, Pinto S, Gerdes N, Lutgens E, Ishimaru N, Busslinger M, Brors B, Kyewski B, Klein L Immunity 42 6 1048-1061 2015/06/16
- Er3+ -Doped Y2O3 Nanophosphors for Near-Infrared Fluorescence Bioimaging Applications Venkatachalam N*, Yamano T*, Hemmer E, Hyodo H, Kishimoto H, Soga K JOURNAL OF THE AMERICAN CERAMIC SOCIETY 96 9 2759-2766 2013/09/01
- Cytotoxic aspects of gadolinium oxide nanostructures for up-conversion and NIR bioimaging. Hemmer E*, Yamano T*, Kishimoto H, Venkatachalam N, Hyodo H, Soga K Acta biomaterialia 9 1 4734-4743 2013/01/01
- Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts. Yamano T, Watanabe S, Hasegawa H, Suzuki T, Abe R, Tahara H, Nitta T, Ishimaru N, Sprent J, Kishimoto H Blood 117 9 2640-2648 2011/03/03
- NIR Bioimaging: Development of Liposome‐Encapsulated, Rare‐Earth‐Doped Y2O3 Nanoparticles as Fluorescent Probes Soga K, Tokuzen K,Tsuji K, Yamano T, Hyodo H,Kishimoto H EUROPEAN JOURNAL OF INORGANIC CHEMISTRY 18 2673-2677 2010/05/14