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研究者情報

データ更新日:2017年09月22日

野村 章洋 (のむら あきひろ) 特任助教 Akihiro Nomura

メール 研究室ウェブサイト

所属組織・役職等

附属病院 循環器内科 / 金沢大学先端医療開発センター
特任助教

教育分野

所属研究室等

循環器病態内科学 / スタディマネジメント部門

学歴

【出身大学院】
金沢大学大学院 博士課程
【出身大学】
金沢大学 医学部 医学科 2006/03 卒業

職歴

マサチューセッツ総合病院 Center for Genomic Medicine Post-doc Research Fellow
小倉記念病院 循環器内科 医員
聖路加国際病院 初期・後期内科研修医、内科チーフレジデント

生年月

所属学会

日本内科学会 総合内科専門医
日本循環器学会 循環器専門医
日本心血管インターベンション治療学会 認定医
日本糖尿病学会

学内委員会委員等

受賞学術賞

○2016年度 Journal of Cardiology 優秀論文賞(2016/09/23)
○吉田育英会 海外派遣留学プログラム奨学生(2014/07/01)

専門分野

循環器内科学、人類遺伝学、統計科学

専門分野キーワード

研究課題

著書

  • 内科レジデントの鉄則 第2版 医学書院 2012/03/07 共著 野村章洋、浅野拓、大屋敷倫代、岡田定

論文

  • Association of Rare and Common Variation in the Lipoprotein Lipase Gene with Coronary Artery Disease. Khera AV, Won HH, Peloso GM, O'Dushlaine C, Liu D, Stitziel NO, Natarajan P, Nomura A, Emdin CA, Gupta N, Borecki IB, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Carey DJ, Murray MF, Kirchner HL, Leader JB, Lavage DR, Manus JN, Hartzel DN, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Lander ES, Rader DJ, Danesh J, Ardissino D, Gabriel S, Willer C, Abecasis GR, Saleheen D, Dewey FE, Kathiresan S. The Journal of the American Medical Association (JAMA). 2017 03 07; 317(9):937-946. 査読有
  • Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels.  Emdin CA, Khera AV, Natarajan P, Klarin D, Won HH, Peloso GM, Stitziel NO, Nomura A, Zekavat SM, Bick AG, Gupta N, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Willer C, Abecasis GR, Felix JF, Vasan RS, Lander E, Rader DJ, Danesh J, Ardissino D, Gabriel S, Saleheen D, Kathiresan S. Journal of the American College of Cardiology. 2016 Dec 27; 68(25):2761-2772.
  • Impact of Baseline Angiographic Complexities Determined by Coronary Artery Bypass Grafting SYNTAX Score on the Prediction of Outcome After Percutaneous Coronary Intervention.  Nakahashi T, Sakata K, Nomura A, Yakuta Y, Gamou T, Terai H, Horita Y, Ikeda M, Namura M, Takamura M, Kawashiri MA, Yamagishi M, Hayashi K. American Journal of Cardiology. 2016 Oct 1; 118(7):974-9. 査読有
  • Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. Eicher JD*, Chami N*, Kacprowski T*, Nomura A*, Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N, Polfus L, Schurmann C, Giri A, Brody JA, Lange LA, Manichaikul A, Hill WD, Pazoki R, Elliot P, Evangelou E, Tzoulaki I, Gao H, Vergnaud AC, Mathias RA, Becker DM, Becker LC, Burt A, Crosslin DR, Lyytikäinen LP, Nikus K, Hernesniemi J, Kähönen M, Raitoharju E, Mononen N, Raitakari OT, Lehtimäki T, Cushman M, Zakai NA, Nickerson DA, Raffield LM, Quarells R, Willer CJ, Peloso GM, Abecasis GR, Liu DJ, Global Lipids Genetics Consortium, Deloukas P, Samani NJ, Schunkert H, Erdmann J; CARDIoGRAM Exome Consortium; Myocardial Infarction Genetics Consortium, Fornage M, Richard M, Tardif JC, Rioux JD, Dube MP, de Denus S, Lu Y, Bottinger EP, Loos RJ, Smith AV, Harris TB, Launer LJ, Gudnason V, Velez Edwards DR, Torstenson ES, Liu Y, Tracy RP, Rotter JI, Rich SS, Highland HM, Boerwinkle E, Li J, Lange E, Wilson JG, Mihailov E, Mägi R, Hirschhorn J, Metspalu A, Esko T, Vacchi-Suzzi C, Nalls MA, Zonderman AB, Evans MK, Engström G, Orho-Melander M, Melander O, O'Donoghue ML, Waterworth DM, Wallentin L, White HD, Floyd JS, Bartz TM, Rice KM, Psaty BM, Starr JM, Liewald DC, Hayward C, Deary IJ, Greinacher A, Völker U, Thiele T, Völzke H, van Rooij FJ, Uitterlinden AG, Franco OH, Dehghan A, Edwards TL, Ganesh SK, Kathiresan S, Faraday N*, Auer PL*, Reiner AP*, Lettre G*, Johnson AD*. (*: Equal contribution) American Journal of Human Genetics. 2016 Jul 07; 99(1):40-55. 査読有
  • Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.  Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, Yanek LR, Manichaikul A, Pazoki R, Mihailov E, Hill WD, Raffield LM, Burt A, Bartz TM, Becker DM, Becker LC, Boerwinkle E, Bork-Jensen J, Bottinger EP, O'Donoghue ML, Crosslin DR, de Denus S, Dubé MP, Elliott P, Engström G, Evans MK, Floyd JS, Fornage M, Gao H, Greinacher A, Gudnason V, Hansen T, Harris TB, Hayward C, Hernesniemi J, Highland HM, Hirschhorn JN, Hofman A, Irvin MR, Kähönen M, Lange E, Launer LJ, Lehtimäki T, Li J, Liewald DC, Linneberg A, Liu Y, Lu Y, Lyytikäinen LP, Mägi R, Mathias RA, Melander O, Metspalu A, Mononen N, Nalls MA, Nickerson DA, Nikus K, O'Donnell CJ, Orho-Melander M, Pedersen O, Petersmann A, Polfus L, Psaty BM, Raitakari OT, Raitoharju E, Richard M, Rice KM, Rivadeneira F, Rotter JI, Schmidt F, Smith AV, Starr JM, Taylor KD, Teumer A, Thuesen BH, Torstenson ES, Tracy RP, Tzoulaki I, Zakai NA, Vacchi-Suzzi C, van Duijn CM, van Rooij FJ, Cushman M, Deary IJ, Velez Edwards DR, Vergnaud AC, Wallentin L, Waterworth DM, White HD, Wilson JG, Zonderman AB, Kathiresan S, Grarup N, Esko T, Loos RJ, Lange LA, Faraday N, Abumrad NA, Edwards TL, Ganesh SK, Auer PL, Johnson AD, Reiner AP, Lettre G. American Journal of Human Genetics. 2016 Jul 7; 99(1):8-21. 査読有

全て表示

  • Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. Khera AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X, van Leeuwen EM, Natarajan P, Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N, Nomura A, Kessler T, Duga S, Bis JC, van Duijn CM, Cupples LA, Psaty B, Rader DJ, Danesh J, Schunkert H, McPherson R, Farrall M, Watkins H, Lander E, Wilson JG, Correa A, Boerwinkle E, Merlini PA, Ardissino D, Saleheen D, Gabriel S, Kathiresan S. Journal of the American College of Cardiology. 2016 Jun 7; 67(22):2578-89. 査読有
  • Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Nagata Y, Teramoto R, Fujino N, Nomura A, Tada H, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M, Hayashi K. American Journal of Cardiology. 2016 Feb 1; 117(3):443-9. 査読有
  • Whole exome sequencing combined with integrated variant annotation prediction identifies a causative myosin essential light chain variant in hypertrophic cardiomyopathy. Nomura A, Tada H, Teramoto R, Konno T, Hodatsu A, Won HH, Kathiresan S, Ino H, Fujino N, Yamagishi M, Hayashi K. Journal of Cardiology. 2016 Feb; 67(2):133-9. 査読有
  • Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Hayashi K, Fujino N, Oka R, Nomura A, Nagata Y, Hodatsu A, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M. Journal of Cardiovascular Electrophysiology. 2015 Oct; 26(10):1081-7. 査読有
  • Successful endovascular treatment for high take off aorto-iliac occlusive disease. Nomura A, Nagashima M, Tomoi Y, Tosaka A, Soga Y. Internal Medicine. 2015; 54(8):921-4. 査読有
  • Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene. Tada H, Kawashiri MA, Nohara A, Saito R, Tanaka Y, Nomura A, Konno T, Sakata K, Fujino N, Takamura T, Inazu A, Mabuchi H, Yamagishi M, Hayashi K. Atherosclerosis. 2015 Jun; 240(2):324-9. 査読有
  • Right Ventricular Hypertrophy is Associated with Cardiovascular Events in Hypertrophic Cardiomyopathy: Evidence from Study with Magnetic Resonance.  Nagata Y, Konno T, Fujino N, Hodatsu A, Nomura A, Hayashi K, Nakamura H, Kawashiri MA, Yamagishi M. Canadian Journal of Cardiology. 2015 Jun;31(6):702-8. 査読有
  • Fragmented QRS Predicts Heart Failure Progression in Patients With Hypertrophic Cardiomyopathy.  Nomura A, Konno T, Fujita T, Tanaka Y, Nagata Y, Tsuda T, Hodatsu A, Sakata K, Nakamura H, Kawashiri MA, Fujino N, Yamagishi M, Hayashi K. Circulation Journal. 2015;79:136-143. 査読有
  • Can next-generation sequencing replace sanger sequencing for screening genetic variant?  Kawashiri MA, Nomura A, Konno T, Hayashi K. Circulation Journal. 2014 Nov 25;78(12):2845-7. 査読有
  • Impact of clinical and echocardiographic characteristics on occurrence of cardiac events in cardiac amyloidosis as proven by endomyocardial biopsy.  Nakahashi T, Arita T, Yamaji K, Inoue K, Yokota T, Hoshii Y, Fukunaga M, Nomura A, Watanabe H, Miura S, Isotani A, Soga Y, Ando K, Iwabuchi M, Yokoi H, Nosaka H, Yamagishi M, Nobuyoshi M. International Journal of Cardiology. 2014 Oct 20;176(3):753-9. doi: 10.1016 査読有
  • Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention.  Kuramitsu S, Yokoi H, Domei T, Nomura A, Watanabe H, Yamaji K, Soga Y, Arita T, Kondo K, Shirai S, Ando K, Sakai K, Iwabuchi M, Nosaka H, Nobuyoshi M. Cardiovascular Diabetology. 2013 May 7;12:74. doi: 10.1186/1475-2840-12-74. 査読有
  • Very long-term outcomes after percutaneous coronary intervention with bare metal stents for unprotected left main coronary artery disease.  Nomura A, Yamaji K, Shirai S, Omata F, Soga Y, Nagashima M, Arita T, Ando K, Sakai K, Goya M, Yokoi H, Iwabuchi M, Nobuyoshi M. EuroIntervention.  2012 Dec 20;8(8):962-9. doi: 10.4244/EIJV8I8A146. 査読有
  • Coexistence of visceral fat and multiple risk factor accumulations is strongly associated with coronary artery disease in Japanese (the VACATION-J study).  Hiuge-Shimizu A, Kishida K, Funahashi T, Okutsu M, Kametani R, Kobayashi H, Nozaki Y, Nomura A, Yokoi H, Yoshizumi T, Ohira T, Nakamura T, Matsuzawa Y, Sumitsuji S, Shimomura I. Journal of Atherosclerosis and Thrombosis. 2012;19(7):657-63. Epub 2012 May 4. 査読有
  • Risk factors of mid-term mortality of patients with infective endocarditis.  Nomura A, Omata F, Furukawa K. European Journal of Clinical Microbiology and Infectious Diseases, 29(11):1355-60, 2010. 査読有

講演・口頭発表等

芸術・フィールドワーク

特許

共同研究希望テーマ

科研費

○若手研究(B)「次世代シークエンサーを用いた家族性肥大型心筋症の新たな病態発症メカニズムの解 明」(2017-2018) 代表者

学域・学類担当授業科目

大学院担当授業科目

他大学の客員教授

教育活動(FD)に関する研究

国際事業協力

留学生参加の社会活動

審議会等の参加

講演可能なテーマ

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