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Researcher Information

last modified：2025/03/02

Professor　KOBAYASHI Masato

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Faculty, Affiliation

Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Health Sciences，Graduate School of Medical Science
Department of Radiological Technology，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University　Doctor　Graduate School, Division of Medical Sciences　Division of health sciences　200609　Completed
【Degree】
Master of health sciences
Doctor of health sciences

Career

Foundation for Biomedical Research and Innovation(-2005/03/31)
University of Fukui　Biomedical Imaging Research Center　COE research associate(2006/10/01-2007/03/30)
University of Fukui　Biomedical imaging research center　Assistant professor(2007/04/01-2009/02/28)
Kanazawa university　Faculty of Health Sciences　Assistant Professor(2009/03/01-2013/03/31)
Kanazawa university　Wellness Promotion Science Center　Tenure-track Assistant Professor(2014/04/01-2019/03/31)
Kanazawa University　Faculty of Health Sciences　Associate Professor(2019/04/01-2022/03/31)
Kanazawa University　Faculty of Health Sciences　Professor(2022/04/01-)
University of Fukui　Biomedical imaging research center　Visiting Researcher(2009/04/01-2021/03/31)
National Institutes of Health　Research Fellow
University of Texas MD Anderson Cancer Center　Visiting Assistant Professor

Year & Month of Birth

Academic Society

The Japanese society of nuclear medicine
Japanese society for molecular imaging
Society of Nuclear Medicine
Japanese society of radiological technology
Japan society of medical physics
The Japanese Society of Nuclear Medicine Technology

Award










Specialities

Radiation science

Speciality Keywords

Nuclear medicine.Biomedical imaging

Research Themes

Combined biomedical functional imaging

Books

Papers

  • 　Biological distribution of orally administrated [123I]MIBG for estimation of gastrointestinal tract absorption.　Kobayashi M, Mizutani A, Muranaka Y, Nishi K, Komori H, Nishii R, Shikano N, Nakanishi T, Tamai I, Kawai K.　Pharmaceutics　14　1　61　2021/12/28
  • 　Exercise inhibits Doxorubicin-induced damage to cardiac vessels and activation of Hippo/YAP-mediated apoptosis.　Rong-Hua T, Kobayashi M, Yang Y, Kleinerman E.　Cancers(Basel)　13　11　2740　2021/06/01
  • 　Inhibition of the hepatic uptake of 99mTc-tetrofosmin using an organic cation transporter blocker.　Nishi K, Kobayashi M, Kikuchi M, Mizutani A, Muranaka Y, Tamai I, Kawai K, Kudo T. 　Pharmaceutics　13　7　1073　2021/07/13
  • 　Differentiation between non-small cell lung cancer and radiation pneumonitis after carbon-ion radiotherapy by 18F-FDG PET/CT texture analysis.　Suga M, Nishii R, Miwa K, Kamitaka Y, Yamazaki K, Tamura K, Yamamoto N, Kohno R, Kobayashi M, Tanimoto K, Tsuji H, Higashi T.　Scientific Reports　11　1　11509　2021/06/01
  • 　Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid.　Kobayashi M, Mizutani A, Okamoto T, Muranaka Y, Nishi K, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K.　Nuclear Medicine and Biology　94-95　92-97　2021/02/05

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  • 　Clinical Value of PET/CT with Carbon-11 4DST in the Evaluation of malignant and benign lung tumors.　Nishii R, Saga T, Sudo H, Togawa T, Kuyama J, Tani T, Maeda T, Kobayashi M, Iizasa T, Shingyoji M, Itami M, Kawamura K, Hashimoto H, Yamazaki K, Kentaro Tamura K, Higashi T.　Annuls of Nuclear Medicine　35　2　211-222　2021/01/02
  • 　[131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma. 　Kobayashi M, Mizutani A, Nishi K, Muranaka Y, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K. 　Nuclear Medicine and Biology　90-91　49-54　2020/09/28
  • 　Transport mechanism and affinity of [99mTc]mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells.　Kobayashi M, Nishi K, Mizutani A, Okudaira H, Nakanishi T, Shikano N, Nishii R, Tamai I, Kawai K.　Nuclear Medicine and Biology　84-85　33-37　2020/01/15
  • 　Longitudinal investigation of Propionibacterium acnes burden and skin physiological function during menstruation in healthy women.　Mukai K, Ogai K, Kobayashi M, Ueda T, Nakajima Y, Nakatani T. 　Structure and Function　18　1　20-30　2019/11/09
  • 　Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol.　Kobayashi M, Nishi K, Mizutani A, Hokama T, Matsue M, Tsujikawa T, Nakanishi T, Nishii R, Tamai I, Kawai K.　Scientific Reports　9　1　13413　2019/09/03
  • 　The pharmacological properties of 3-arm or 4-arm DOTA constructs for conjugation to a-melanocyte-stimulating hormone analogues for melanoma imaging　Kobayashi M, Kato T, Washiyama K, Ihara M, Mizutani A, Nishi K, Flores LG 2nd, Nishii R, Kawai K.　PLOS ONE　2019/02/04
  • 　Comparison of wiping methods for the removal of cleaning agent residue from hair follicles.　Aoki M, Ogai K, Matsumoto M, Susa H, Yamada K, Yamatake T, Kobayashi M, Sugama J.　Skin Res Technol　2019/01/03
  • 　Different efflux transporter affinity and metabolism of 99mTc-2-methoxyisobutylisonitrile and 99mTc-tetrofosmin for multidrug resistance monitoring in cancer.　Kobayashi M, Tsujiuchi T, Mizutani A, Nishi K, Nakanishi T, Nishii R, Fukuchi K, Tamai I, Kawai K.　Pharm Res　36　1　18　2018/11/29
  • 　Comparison of ceramide retention in the stratum corneum between dry skin and normal skin using animal model with fluorescent imaging method.　Aoki M, Ogai K, Kobayashi M, Minematsu T, Nakatani T, Okuwa M, Sanada H, Sugama J. 　Skin Res Technol　2018/10/27
  • 　1,2,4-Triazole-based Compounds as PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [11C]PS13 for Quantitative Imaging.　Shrestha S, Singh P, Cortes-Salva MY, Jenko KJ, Ikawa M, Kim MJ, Kobayashi M, Morse CL, Zoghbi SS, Gladding RL, Fujita M, Innis RB, Pike VW.　ACS Chemical Neuroscience　9　11　2620-2627　2018/11/21
  • 　123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug metabolizing enzyme activity.　Mizutani A, Kobayashi M, Fujita KI, Takahashi K, Hokama T, Takasu H, Nishi K, Nishii R, Shikano N, Fukuchi K, Kawai K.　Nucl Med Commun　39　9　825-833　2018/09
  • 　The changes of chronic leg oedema after recumbent position at night in chair-bound elderly Japanese individuals.　Iuchi T, Tsuchiya S, Sato A, Dai M, Imran I, Kobayashi M, Sugama J. 　Lymphoedema Research and Practice　6　1　1-9　2018/05/09
  • 　Diagnosis of brain tumors using system A amino acid transport PET imaging with C-11-MeAIB: A comparison study with C-11-methionine PET imaging.　Nishii R, Higashi T, Kagawa S, Arimoto M, Kishibe Y, Takahashi M, Yamada, Saiki M, Arakawa Y, Yamauchi H, Okuyama C, Hojo M, Munemitsu T, Sawada M, Kobayashi M, Kawai K, Nagamachi S, Hirai T, Miyamoto S.　Contrast Media Mol Imaging　2018　1292746　2018/06/20
  • 　Selected PET radiomic features remain the same.　Tsujikawa T, Tsuyoshi H, Kanno M, Yamada S, Kobayashi M, Narita T, Kimura H, Fujieda S, Yoshida Y, Okazawa H.　Oncotarget　9　29　20734-20746　2018/04/17
  • 　Influences of different methods of cleaning agent removal on the effectiveness of skin dirt removal.　Matsumoto M, Ogai K, Ohashi R, Tanaka K, Aoki M, Kobayashi M, Sugama J. 　The Society for Nursing Science and Engeenring　2018
  • 　Changes in dermal structure and skin oxidative stress in overweight and obese Japanese males after weight loss: a longitudinal observation study.　Matsumoto M, Ogai K, Aoki M, Urai T, Yokogawa M, Tawara M, Kobayashi M, Minematsu T, Sanada H, Sugama J. 　Skin Research and Technology　2018/01/27
  • 　Development of radioiodine-labeled acetaminophen for specific, high-contrast imaging of malignant melanoma.　Zhu WJ, Kobayashi M, Yamada K, Mizutani A, Nishi K, Shikano N, Nishii R, Kunishima M, Kawai K.　Nuclear Medicine and Biology　59　16-21　2018/01/03
  • 　エアマットレス使用時の枕のあて方が上肢・胸部の筋の硬さと自覚症状に及ぼす影響．　浦井珠恵，松本勝，井内映美，小林正和，西村誠次，須釜淳子．　Journal of Wellness and Health Care　41　2　151-158.　2017/12
  • 　日本放射線技術学会の海外派遣事業における派遣者の動向及び業績の調査　小林正和，田中利恵，松原孝祐，森岡茂晃，辻岡勝美，有村秀孝，上田克彦，小倉明夫，宮地利明.　日本放射線技術学会雑誌　73　10　1061-1065　2017/10
  • 　Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176. 　Fujita M, Kobayashi M, Ikawa M, Gunn RN, Rabiner EA, Owen DR, Zoghbi SS, Haskali MB, Telu S, Pike VW, Innis RB. 　EJNMM Research　7　1　84　2017/10/16
  • 　Objective assessment of leg edema using ultrasonography with a gel pad　Iuchi T, Kobayashi M, Tsuchiya S, Ohno N, Dai M, Matsumoto M, Ogai K, Sato A, Sawazaki T, Miyati T, Tanaka S, Sugama J.　Plos one　2017/08/09
  • 　Noninvasive longitudinal monitoring of the angiogenesis in a murine excisional cutaneous wound healing model using a high-resolution three-dimensional ultrasound imaging.　Mukai K, Zhu WJ, Nakajima Y, Kobayashi M, Nakatani T.　Skin Research and Technology　2017
  • 　11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than does 11C-(R)-PK11195.　Kobayashi M, Jiang T, Telu S, Zoghhi SS, Gunn R, Rabiner EA, Owen DR, Guo Qi, Pike VW, Innis RB, Fujita M.　Journal of Cerebral Blood Flow and Metabolism　2017
  • 　Wash or wipe? A comparative study of skin physiological changes between water washing and wiping after skin cleaning.　Ogai K, Matsumoto M, Aoki M, Ota R, Hashimoto K, Wada R, Kobayashi M, Sugama J. 　Skin Research and Technology　2017
  • 　Difference in accumulation and the transport mechanism of L- and D-methionine in high- and low-grade human glioma cells. 　Kobayashi M, Mizutani A, Nishi K, Nakajima S, Shikano N, Nishii R, Fukuchi K, Kawai K. 　Nuclear Medicine and Biology　44　78-82　2017
  • 　Relationship between [14C]MeAIB uptake and amino acid transporter family gene expression levels or proliferative activity in human carcinoma cells: comparison with [3H]Methionine uptake.　Kagawa S, Nishii R, Higashi T, Yamaguchi H, Ogawa E, Ono M, Okudaira H, Kobayashi M, Yoshimoto M, Shikano N, Kawai K.　Nuclear Medicine and Biology　49　8-15　2017
  • 　Assessment of Amino Acid/Drug Transporters for Renal Transport of [18F]Fluciclovine (anti-[18F]FACBC) in Vitro.　Ono M, Baden A, Okudaira H, Kobayashi M, Kawai K, Oka S, Yoshimura H.　International Journal of Molecular Sciences　17　10　pii: E1730　2016
  • 　Increased level of tumor necrosis factor-alpha (TNF-α) on the skin of Japanese obese males: measured by quantitative skin blotting.　Ogai K, Matsumoto M, Aoki M, Minematsu T, Kitamura KI, Kobayashi M, Sanada H, Sugama J.　International Journal of Cosmetic Science　38　5　462-9　2016
  • 　Stimultaneous acquisition of 99mTc and 123I-labeled radiotracers using a preclinical SPECT scanner with CZT detectors. 　Kobayashi M, Matsunari I, Nishi K, Mizutani A, Miyazaki Y, Ogai K, Sugama J, Shiba K, Kawai K, Kinuya S.　Annals of Nuclear Medicine　30　4　263-271　2015
  • 　[14C]Fluciclovine (alias anti-[14C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells.　Ono M, Oka S, Okudaira H, Nakanishi T, Mizotani A, Kobayashi M, Schuster DM, Goodman MM, Shirakami Y, Kawai K. 　Nuclear Medicine and Biology　42　11　887-892　2015
  • 　Impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion SPECT using cadmium-zinc telluride detectors in the rat.　Mizutani A, Matsunari I, Kobayashi M, Nishi K, Fujita W, Miyazaki Y, Nekolla SG, Kawai K. 　EJNMMI Physics　2　1　2015
  • 　Comprison of image quality with 62Cu and 64Cu-labeled radiotracers in Positron Emission Tomography whole-body phantom imaging.　Kobayashi M, Mori T, Tsujikawa T, Mizutani A, Ogai K, Sugama J, Kiyono Y, Kawai K, Okazawa H.　Hellenic Journal of Nuclear Medicine　18　2　103-107　2015
  • 　Development of radioiodine-labeled 4-hydroxyphenylcysteamine for specific diagnosis of malignant melanoma.　Kobayashi M, Nishii R, Shikano N, Florens LG 2nd, Mizutani A, Ogai K, Sugama J, Nagamachi S, Kawai K. 　Nuclear Medicine and Biology　42　6　536-540　2015
  • 　A strategy for improving FDG accumulation for early detection of metastasis for primary pancreatic cancer: stimulation of the Warburg effect in AsPC-1 cells.　Ogura M, Shikano N, Nakajima S, Sagara J, Yamaguchi N, Kusanagi K, Okui Y, Mizutani A, Kobayashi M, Kawai K.　Nuclear Medicine and Biology　42　5　475-481　2015
  • 　In vivo radioactive metabolism analysis for individualized medicine: a basic study of a new method of CYP activity assay using 123I-IMP.　Nishi K, Mizutani A, Shikano N, Fujita K, Kobayashi M, Ono M, Nishii R, Sasaki Y, Kinuya S, Kawai K. 　Nuclear Medicine and Biology　42　2　171-176　2014
  • 　Development of an improved method for quantitative analysis of skin blotting: increasing reliability and applicability for skin assessment.　Ogai K, Matsumoto M, Minematsu T, Kitamura K, Kobayashi M, Sugama J, Sanada H. 　International Journal of Cosmetic Science　37　4　425-432　2015
  • 　Accumulation of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid in prostate cancer due to androgen-induced expression of amino-acid transporters.　Okudaira H, Oka S, Ono M, Nakanishi T, Shuster DM, Kobayashi M, Goodman MM, Tamai I, Kawai K, Shirakami Y.　Molecular Imaging and Biology　16　6　756-764　2014
  • 　Application of a medium-energy collimator for I-131 imaging after ablation treatment of differentiated thyroid cancer.　Kobayashi M, Wakabayashi H, Kayano D, Konishi T, Kojima H, Okuda K, Yoneyama H, Tsushima H, Onoguchi M, Kawai K, Kinuya S.　Annuls of Nuclear Medicine　28　6　551-558　2014
  • 　Effect of surrounding materials on iterative reconsruction based spatial resolution, and annihilations outside the source assessed by a small animal PET scanner. 　Miyazaki Y, Kobayashi M, Komatsu R, Hayashi A, Yonezawa S, Kawai K, Matsudaira M, Shiozaki J, Matsunari I.　Annals of Nuclear Medicine　28　6　512-522　2014
  • 　Performance evaluation of the eXplore speCZT preclinical imaging system.　Matsunari I, Miyazaki Y, Kobayashi M, Nishi K, Mizutani A, Kawai K, Hayashi A, Komatsu R, Yonezawa R, Kinuya S. 　Annals of Nuclear Medicine　28　6　484-497　2014
  • 　Transport mechanism of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan.　Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K. 　Nuclear Medicine and Biology　41　4　338-342　2014
  • 　Improved detection of sentinel lymph nodes in SPECT/CT images acquired using a low-medium-energy-general-purpose (LMEGP) collimator　Yoneyama H, Tsushima H, Kobayashi M, Konishi T, Kojima H, Onoguchi M, Nakajima K, Kinuya S　CLINICAL NUCLEAR MEDICINE　39　1　e1-6　2014
  • 　Diagnostic usefulness of an amino acid tracer, α-[N-methyl-11C]-methylaminoisobutyric acid ( 11C-MeAIB), in the PET diagnosis of chest malignancies.　Nishii R,Higashi T,Kagawa S,Kishibe Y,Takahashi M,Yamauchi H,Motoyama H,Kawakami K,Nakaoku T,Nohara J,Okamura M,Watanabe T,Nakatani K,Nagamachi S,Tamura S,Kawai K,Kobayashi M　ANNALS OF NUCLEAR MEDICINE　27　9　808-821　2013
  • 　Kinetic analyses of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2　Okudaira H, Nakanishi T, Oka S, Kobayashi M, Tamagami H, Schuster DM, Goodman MM, Shirakami Y, Tamai I, Kawai K　Nuclear Medicine and Biology　40　5　670-675　2013
  • 　Appropriate collimators in a small animal SPECT scanner with CZT detector　Higaki Y, Kobayashi M, Uehara K, Hanaoka H, Arano Y, Kawai K　Annals of Nuclear Medicine　27　3　271-278　2013
  • 　Pharmacokinetic alteration of 99mTc-MAG3 using serum protein binding displacement method　Nishi K, Kobayashi M, Nishii R, Shikano N, Takamura N, Kuga N, Yamasaki K, Nagamachi S, Tamura S, Otagiri M, Kawai K　Nuclear Medicine and Biology　40　3　366-370　2013
  • 　Transport mechanism of 11C-labeled L- and D-methionine in human-derived tumor cells　Kobayashi M, Hashimoto F, Ohe K, Nadamura T, Nishi K, Shikano N, Nishii R, Higashi T, Okazawa H, Kawai K　Nuclear Medicine and Biology　39　8　1213-1218　2012
  • 　N-Isopropyl-p-iodoamphetamine hydrochloride (IMP) is predominantly metabolized by CYP2C19　Fujita K, Sugiyama M, Akiyama Y, Hioki K, Kunishima M, Nishi K, Kobayashi M, Kawai K, Sasaki Y　Drug Metabolism and Disposition　33　2　843-846　2012
  • 　Appropriate parameters of ordered-subset expectation maximization algorithm on measurement of myocardial blood flow and oxygen consumption with 11C-Acetate　Kobayashi M, Mori T, Kiyono Y, Tsujikawa T, Maruyama R, Higaki Y, Shikano N, Nishii R, Kawai K, Kudo T, Okazawa H　Nuclear Medicine Communications　33　2　130-138　2012
  • 　Functional characterization of apical transporters expressed in rat proximal tubular cells (PTCs) in primary culture　Nakanishi T, Fukushi A, Sato M, Shirasaka Y, Ohe K, Kobayashi M, Kawai K, Tamai I.　Molecular Pharmaceutics　8　6　2142-2150　2011/06
  • 　Cerebral oxygen metabolism of rats using injectable 15O-oxygen with a steady-state method.　Kobayashi M, Mori T, Kiyono Y, Tiwari VN, Maruyama R, Kawai K, Okazawa H. 　JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　33　2　130-138　2012/01
  • 　New Radiosynthesis of 2-deoxy-2-[18F]fluoroacetamido-D-glucopyranose and its evaluation as a bacterial infections imaging agent.　Martinez ME, Kiyono Y, Noriki S, Inai K, Mandap KS, Kobayashi M, Mori T, Tokunaga Y, Tiwari VN, Okazawa H, Fujibayashi Y, Ido T.　NUCLEAR MEDICINE AND BIOLOGY　38　6　807-817　2011/08
  • 　Kikuchi-fujimoto disease PET/CT assessment of a rare cause of cervical lymphadenopathy.　Tsujikawa T, Tsuchida T, Imamura Y, Kobayashi M, Asahi S, Shimizu K, Tsuji K, Okazawa H, Kimura H.　CLINICAL NUCLEAR MEDICINE　36　8　661-664　2011/08
  • 　Development of an H215O steady-state method combining a bolus and slow increasing injection with a multi-programming syringe pump. 　Kobayashi M, Kiyono Y, Maruyama R, Mori T, Kawai K, Okazawa H.　JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　31　2　527-534　2011/02
  • 　Putative Transport Mechanism and Intracellular Fate of Anti-18F-FACBC (Trans-1-amino-3-18F-fluorocyclobutanecarboxylic Acid) in human Prostate Cancer.　Okudaira H, Shikano N, Nishii R, Miyagi T, Yoshimoto M, Kobayashi M, Ohe K, Nakanishi T, Tamai M, Namiki M, and Kawai K. 　JOURNAL OF NUCLEAR MEDICINE　52　5　822-829　2011/05
  • 　Early response assessment in prostate carcinoma by 18F-Fluorothymidine following anticancer therapy with docetaxel using preclinical tumour models. 　Oyama N, Hasegawa Y, Kiyono Y, Kobayashi M, Fujibayashi Y, Ponde DE, Dence C, Welch MJ, Yokoyama O.　EUROPEAN JOURNAL OF NUCLEAR MEDICINE　38　1　81-89　2011/01
  • 　Radioiodinated 4-iodo-L-meta-tyrosine, a system L selective artificial amino acid: molecular design and transport characterization in Chinese hamster ovary cells (CHO-K1 cells).　Shikano N, Kotani T, Nakajima S, Ogura M, Nakazawa S, Sagara J, Kobayashi M, Baba T, Yamaguchi N, Kubota N, Kawai K.　NUCLEAR MEDICINE AND BIOLOGY　37　8　903-910　2010/08
  • 　Clinical implication and prognosis of normal baseline cerebral blood flow with impaired vascular reserve in patients with major cerebral artery occlusive disease.　Isozaki M, Arai Y, Kudo T, Kiyono Y, Kobayashi M, Kubota T, Kikuta KI, Okazawa H　ANNALS OF NUCLEAR MEDICINE　2010/05
  • 　Uptake of 3-[125I]iodo-α-methyl-L-tyrosine into colon cancer DLD-1 cells: characterization and inhibitory effect of natural amino acids and amino acid-like drugs.　Shikano N, Ogura M, Okudaira H, Nakajima S, Kotani T, Kobayashi M, Nakazawa S, Baba T, Yamaguchi N, Kubota N, Iwamura Y, Kawai K　NUCLEAR MEDICINE AND BIOLOGY　37　2　197-204　2010/02
  • 　Stimulation of 125I-3-iodo-α-methyl-L-tyrosine in chinese hamster ovary (CHO-K1) by tyrosine esters.　Shikano N, Ogura M, Sagara J, Nakajima S, Kobayashi M, Baba T, Yamaguchi N, Iwamura Y, Kubota N, Kawai K　NUCLEAR MEDICINE AND BIOLOGY　37　2　 189-196　2010/02
  • 　Comparison of the transcellular transport of FDG and D-Glucose by the kidney epithelial cell line LLC-PK1.　Kobayashi M, Shikano N, Nishii R, Kiyono Y, Araki H, Nishi K, Oh M, Okudaira H, Ogura M, Yoshimoto M, Okazawa H, Fujibayashi Y, Kawai K　NUCLEAR MEDICINE COMMUNICATIONS　31　2　141-146　2010/02
  • 　Automatic labeling method for injectable 15O-oxygen using hemoglobin-containing liposome vesicles and its application for measurement of brain oxygen consumption by PET.　Tiwari VN, Kiyono Y, Kobayashi M, Mori T, Kudo T, Okazawa H, Fujibayashi Y　NUCLEAR MEDICINE AND BIOLOGY　37　1　77-83　2010/01
  • 　Effects of transmission scan protocol and attenuation correction method on normal database of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) brain positron emission tomography study　Kobayashi M, Sugimoto K, Maruyama R, Kudo T, Tsujikawa T, Kiyono Y, Onoguchi M, Kawai K, Fujibayashi Y, Okazawa H　Nippon Housyasen Gijutsu Gakkai Zasshi　66　1　42-48　2010/01
  • 　Functional images reflect aggressiveness of endometrial carcinoma: estrogen receptor expression combined with FDG-PET　Tsujikawa T, Yoshida Y, Kudo T, Kiyono Y, Kurokawa T, Kobayashi M, Tsuchida T, Fujibayashi Y, Kotsuji F, Okazawa H　JOURNAL OF NUCLEAR MEDICINE　50　10　1598-1604　2009/10
  • 　Vasodilatory effect of adenosine triphosphate does not change cerebral blood flow: a PET study with 15O-water.　Hussain R, Tsuchida T, Kudo T, Kobayashi M, Tsujikawa T, Kiyono Y, Fujibayashi Y, Okazawa H　ANNALS OF NUCLEAR MEDICINE　23　8　717-723　2009/08
  • 　Validation of the calculation of the clearance rate constant (kmono) of [11C]acetate using parametric kmono image for myocardial oxidative metabolism　NUCLEAR MEDICINE AND BIOLOGY　36/　8　877-882　2009/08
  • 　Competitive displacement of serum protein binding of radiopharmaceuticals with amino-Acid infusion investigated with N-isopropyl-p-123I-iodoamphetamine　Kuga N, Shikano N, Takamura N, Nishii R, Yamasaki K, Kobayashi M, Nagamachi S, Tamura S, Kawai K　JOURNAL OF NUCLEAR MEDICINE　50　8　1378-1383　2009/08
  • 　Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism　Yoshii Y, Furukawa T, Yoshii H, Mori T, Kiyono Y, Waki A, Kobayashi M, Tsujikawa T, Kudo T, Okazawa H, Yonekura Y, Fujibayashi Y　Cancer Science　100　5　821-827　2009/05
  • 　Radio-cooper labeled Cu-ATSM: an indicator of quiescent but clonogenic tumor cells under mild hypoxia　Oh M, Tanaka T, Kobayashi M, Furukawa T, Mori T, Fujieda S, Fujibayashi Y　NUCLEAR MEDICINE AND BIOLOGY　36　4　419-426　2009/04
  • 　Development of microwave-based automated nucleophilic [18F]fluorination system and its application for the production of [18F]flumazenil.　Mandap KS, Ido T, Kiyono Y, Kobayashi M, Lohith TG, Mori T, Kasamatsu S, Kudo T, Okazawa H, Fujibayashi Y.　NUCLEAR MEDICINE AND BIOLOGY　36　4　403-409　2009/04
  • 　Preparation and evaluation of ethyl [18F]Fluoroacetate as a pro-radiotracer of [18F]Fluoroacetate for the measurement of glial metabolism by PET　Mori T, Sun LQ, Kobayashi M, Kiyono Y, Okazawa H, Furukawa T, Kawashima H, Welch MJ, Fujibayashi Y　NUCLEAR MEDICINE AND BIOLOGY　36　2　155-162　2009/02
  • 　Basic evaluation of FES-hERL PET tracer-reporter gene system for in vivo monitoring of adenoviral-mediated gene therapy　Lohith TG, Furukawa T, Mori T, Kobayashi M, Fujibayshi Y　Molecular Imaging and Biology　10　5　245-252　2008/09
  • 　Shorter examination method for the diagnosis of misery perfusion using count-based OEF elevation in 15O-Gas PET　Kobayashi M, Kudo T, Tsujikawa T, Isozaki M, Arai Y, Fujibayashi Y, Okazawa H　JOURNAL OF NUCLEAR MEDICINE　49　2　 242-246　2008/02
  • 　Distinctive FDG and FES accumulation pattern of two tamoxifen treated patients with endometrial hyperplasia　Tsujikawa T, Okazawa H, Yoshida Y, Mori T, Kobayashi M, Tsuchida T, Fujibayashi Y　ANNALS OF NUCLEAR MEDICINE　22　1　73-77　2008/01
  • 　Does partial volume corrected maximum SUV based on count recovery coefficient in 3D-PET/CT correlate with clinical aggressiveness of non-Hodgkin lymphoma?　Tsujikawa T, Ohtsuka H, Morita N, Saegusa H, Kobayashi M, Okazawa H, Nishitani H　ANNALS OF NUCLEAR MEDICINE　22　1　23-30　2008/01
  • 　In vivo imaging of estrogen receptor concentration in the endometrium and myometrium using FES PET-influence of menstrual cycle and endogenous estrogen level　Tsuchida T, Okazawa H, Mori T, Kobayashi M, Yoshida Y, Fujibayashi Y, Itoh H　NUCLEAR MEDICINE AND BIOLOGY　34　2　205-210　2007/02
  • 　Can reductions in baseline CBF and vasoreactivity detect misery perfusion in chronic cerebrovascular disease?　Okazawa H, Tsuchida T, Kobayashi M, Arai Y, Pagani M, Isozaki M, Yonekura Y　EUROPEAN JOURNAL OF NUCLEAR MEDICINE　34　1　121-129　2007/01
  • 　Diagnosis of misery perfusion using noninvasive O-15 gas PET　Kobayashi M, Okazawa H, Tsuchida T, Kawai K, Fujibayashi Y, Yonekura Y　JOURNAL OF NUCLEAR MEDICINE　47　10　2006　2006/10
  • 　Effects of 5-HT1B/1D receptor agonist rizatriptan on cerebral blood flow and blood volume in normal circulation　Okazawa H, Tsuchida T, Pagani M, Mori T, Kobayashi M, Tanaka F, Yonekura Y　JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　26　1　92-98　2006/01
  • 　123I-BMIPP, a radiopharmaceutical for myocardial fatty acid metabolism scintigraphy, could be utilized in bacterial infection imaging.　Muranaka Y, Mizutani A, Kobayashi M, Nakamoto K, Matsue M, Takagi F, Okazaki K, Nishi K, Yamazaki K, Nishii R, Shikano N, Okamoto S, Maki H, Kawai K.　Pharmaceutics.　14　5　1008　2022/05/07
  • 　Evaluation of L-Alanine Metabolism in Bacteria and Whole-Body Distribution with Bacterial Infection Model Mice. 　Muranaka Y, Matsue M, Mizutani A, Kobayashi M, Sato K, Kondo A, Nishiyama Y, Ohata S, Nishi K, Yamazaki K, Nishii R, Shikano N, Okamoto S, Kawai K. 　Int J Mol Sci　24　5　4775　2023/03/01
  • 　Measurement of hepatic CYP3A4 and 2D6 activity using radioiodine-labeled O-desmethylvenlafaxine.　Mizutani A, Kobayashi M, Aibe R, Muranaka Y, Nishi K, Kitamura M, Suzuki C, Nishii R, Shikano N, Magata Y, Ishida Y, Kunishima M, Kawai K. 　Int J Mol Sci　23　19　11458　2022/09/28
  • 　Biological distribution after oral administration of radioiodine-labeled acetaminophen to estimate gastrointestinal absorption function via OATPs, OATs, and/or MRPs.　Sato K, Mizutani A, Muranaka Y, Yao J, Kobayashi M, Yamazaki K, Nishii R, Nishi K, Nakanishi T, Tamai I, Kawai K.　Pharmaceutics　2023/02/02
  • 　A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells.　Sato K, Seki T, Mizutani A, Muranaka Y, Hirota S, Nishi K, Yamazaki K, Nishii K, Nakanishi T, Tamai I, Kawai K. Kobayashi M　Front. Pharmacol　13　1069321　2023/01/11
  • 　Characteristics of developmental and healing process of docetaxel-induced lower limb edema in patients with stage IV breast cancer: A case series.　Imakata Y, Sugama J, Ichihashi S, Oohashi F, Kobayashi M, Oe M. 　Palliative Medicine Reports　4　1　20　2023/02/20
  • 　Estimation of post-therapeutic liver reserve capacity using 99mTc-GSA Scintigraphy prior to carbon-ion radiotherapy for liver tumors.　Yamazaki K, Nishii R, Mizutani Y, Makishima H, Kaneko T, Isobe Y, Terada T, Tamura K, Tani T, Kobayashi M, Wakamatsu M, Tsuji H, Higashi T　Eur J Nucl Med Mol Imaging　50　2　581-592　2023/01
  • 　Comparison of L- and D-Amino Acids for Bacterial Imaging in Lung Infection Mouse Model.　Muranaka Y, Mizutani A, Kobayashi M, Nakamoto K, Matsue M, Nishi K, Yamazaki K, Nishii R, Shikano N, Okamoto S, Kawai K.　International Journal of Molecular Sciences　23　5　2467　2022/02/23

Conference Presentations

  • 123I-MIBGを用いた消化管吸収機能の選択的測定法の検討(conference：第58回日本核医学会)(2018/11/15)
  • Impact of image acquisition time on textural features in 18F-FDG PET/MR.(conference：The Society of Nuclear Medicine and Molecular Imaging 2017 Annual Meeting)(2017/06/10)
  • Establishment of novel moist Establishment of novel moisturizer application method for dry skin focused on ceramide kinetics-Preliminary test on normal rat skin.(conference：The 27th conference of European Wound Management Association 2017)(2017/05/03)

Others

Arts and Fieldwork

Patent

○細菌又は細胞の分類方法，アミノ酸の輸送特性の分類方法，菌感染の診断補助方法並びに癌の診断補助方法

Theme to the desired joint research

○New radiological technology

Grant-in-Aid for Scientific Research

○「ナトリウム共役能動輸送型糖輸送体を標的としたセラノスティクス薬剤の開発」(2021-2024)　
○「副作用が懸念される薬物の腎尿細管分泌機序の解明と新規腎機能核医学画像測定法の開発」(2018-2020)　
○「高精度多剤耐性予測法に基づく内用放射線治療の効果予測法とがん治療効果増強法の開発」(2017-2019)　
○「精神神経疾患の個体差を克服する個別化薬物療法に有用な分子標的放射性診断薬の開発」(2016-2017)　
○「抗がん剤の個別化治療を可能とするSPECTを利用した高精度多剤耐性予測法の確立」(2015-2017)　
○「癌関連トランスポーター発現解析に基づく機能性分子発現系による腫瘍診断薬の開発戦略」(2014-2016)　
○「半導体検出器を搭載した最新型小動物用SPECT/CT装置における定量測定法の確立」(2012-2014)　
○「静注用<sup>15</sup>O標識薬剤における脳循環代謝測定の迅速化と薬物療法効果判定の有用性の検討」(2010-2011)　
○「脳内神経変性疾患に対する再生医療・遺伝子治療効果判定に有用な放射性診断薬の開発」(2008-2011)　
○「急性期虚血性脳疾患におけるPET診断簡略化を目指した自動検出解析システムの開発」(2007-2009)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Radiation Measurement(2022)
○Radiation Protection and Safety Experiment(2022)
○GS English Language Courses for Undergraduates 1(2022)
○Radiation Measurement(2022)
○Radiation Protection and Safety Experiment(2022)
○Public Health(2022)
○Public Health(2021)
○Radiation Measurement(2021)
○Radiation Protection and Safety Experiment(2021)
○Radiation Protection and Safety Experiment(2020)
○Radiation Measurement(2020)
○Public Health(2020)
○Basic Health Science 1(2020)
○臨床実習1(2019)
○臨床実習2(2019)
○公衆衛生学(2019)
○Introduction to Region-studies(2019)
○Presentation and Debate (Freshman Seminar II)(2019)
○Freshman Seminar I(2019)
○Wellness Promotion Science(2014)
○Radiological Mechinery,Experiment 1(2011)
○Radiological Mechinery,Experiment 1(2010)
○Radiation Protection and Safety Experiment(2010)
○Experiments in Radiation Protection and Safety(2009)

Classes (Graduate Schools)

○Analytics for Functional Imaging: Seminar(2020)
○Analytics for Functional Imaging: Lecture(2020)
○Preventive Medicine(2020)
○Processing & Anal. for Biofunctional Imaging: Res.(2020)
○Analytics for Physical Function: Seminar(2020)
○Analytics for Physical Function: Lecture(2020)
○Research Design in Medical Radiation Science: Lec.(2020)
○生体機能解析学特論(2019)
○Processing & Anal. for Biofunctional Imaging: Res.(2019)
○Research Design in Medical Radiation Science: Lec.(2019)
○Analytics for Physical Function: Seminar(2019)
○Preventive Medicine(2019)
○Analytics for Functional Imaging: Lecture(2019)
○Preventive Medicine(2018)
○Wound Management: Seminar(2018)
○Analytics for Physical Function: Lecture(2018)
○Analytics for Physical Function: Seminar(2018)
○Analytics for Physical Function: Seminar(2017)
○Analytics for Physical Function: Lecture(2017)
○Wound Management: Seminar(2017)
○生体機能解析学特論(2016)
○生体機能解析学演習(2016)
○生体機能解析学特論(2015)
○生体機能解析学演習(2015)
○生体機能解析学特論(2014)
○生体機能解析学演習(2014)

International Project

International Students

Lecture themes

Others (Social Activities)

○北陸大学(20190401-20190930)　北陸大学医療保健学部医療技術学科の非常勤講師

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