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Researcher Information

last modified:2020/04/10

Associate Professor TAOKA Azuma

Mail Laboratory Website

Faculty, Affiliation

College and School Educational Field

Division of Natural Sciences, Graduate School of Natural Science and Technology
Division of Natural System, Graduate School of Natural Science and Technology
Course in Biosystems, School of Biological Science and Technology, College of Science and Engineering

Laboratory

 TEL:076-264-6234 FAX:076-264-6230

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Department of Life Science 200403 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University Department of Biology 199903
【Degree】
Ph. D.
Master of Science

Career

Postdoctoral researcher Faculty of Science(2004/09/13-2007/08/31)
VBL Postdoctoral researcher Venture Business Laboratory(2007/09/01-2008/03/31)

Year & Month of Birth

1976/02

Academic Society

The Japanese Biochemical Society
The Japanese Society of Microbial Ecology
American Society for Microbiology
Japanese Society for Bacteriology

Society of Genome Microbiology, Japan

Award

Society of Genome Microbiology, Japan

Specialities

Functional biochemistry、Applied microbiology

Speciality Keywords

Prokaryotic organelle, Bacterial cytoskeleton, Magnetotactic Bacteria, Magnetosome

Research Themes

Molecular mechanisms for magnetic organelle 'magnetosome' of magnetotactic bacnteria

Molecular mechanisms for magnetic organelle 'magnetosome' of magnetotactic bacnteria Magnetic bacteria are unique bacteria that are able to sense magnetism with a prokaryotic cell organelle called magnetosome which functions as a magnetic compass. Magnetic bacteria take in iron from the environment and synthesize magnetite crystals in their cellular membrane vesicles. Magnetosome is a complex intracellular structure with these membrane vesicles arranged in a string-like pattern along the cellular skeleton. We conduct research using biochemical and molecular biological techniques and various microscopic techniques in order to explain how magnetosomes develop and function at the molecular level. We aim to explain organelle development in prokaryotic organisms and the mechanism of biomineralization with this research.

Books

  •  Azuma Taoka, Yoshihiro Fukumori Biological Magnetic Materials and Applications Springer 2018/07

Papers

  •  Diversity of physical properties of bacterial extracellular membrane vesicles revealed through atomic force microscopy phase imaging Yousuke Kikuchi, Nozomu Obana, Masanori Toyofuku, Noriyuki Kodera, Takamitsu Soma, Toshio Ando, Yoshihiro Fukumori, Nobuhiko Nomura, Azuma Taoka Nanoscale in press 2020/03/23
  •  Tree of motility – A proposed history of motility systems in the tree of life. Miyata, M., Robinson, R.C., Uyeda, T.Q.P., Fukumori, Y., Fukushima, S., Haruta, S., Homma, M., Inaba, K., Ito, M., Kaito, C., Kato, K., Kenri, T., Kinosita, Y., Kojima S., Minamino, T., Mori, H., Nakamura, S., Nakane, D., Nakayama, K., Nishiyama, M., Shibata, S., Shimabukuro, K., Tamakoshi, M., Taoka, A., Tashiro, Y., Tulum, I., Wada, H., and Wakabayashi, K. Genes to Cells 25 6-21 2020/01/19
  •  Membranolytic Effects of KT2 on Gram-Negative Escherichia coli Evaluated by Atomic Force Microscopy T. Theansungnoen, N. Jangpromma, P. Anwised, S. Daduang, Y. Fukumori, A. Taoka, S. Klaynongsruang Applied Biochemistry and Microbiology 55 5 495-505 2019/09
  •  Measuring magnetosomal pH of the magnetotactic bacterium Magnetospirillum magneticum AMB-1 using pH-sensitive fluorescent proteins Yukako Eguchi, Yoshihiro Fukumori, Azuma Taoka Bioscience, Biotechnology, and Biochemistry 2018/07
  •  Role of the Bacterial Actin-like Cytoskeleton to Tethering Magnetic Organelle Azuma TAOKA, Yoshihiro FUKUMORI 58 2 91-93 2018/04

show all

  •  Gradual Deformation of Bacterial Cell Morphology due to the Effect of Non-thermal Atmospheric Pressure Plasma jet-Treated Water (PTW) Begum, A., Chiba, R., Ishijima, T., Kakikawa, M., Taoka , A., Pervez, M. R., Innomata, T., Uesugi, Y., Tanaka Y., IEEE Transactions on Radiation and Plasma Medical Sciences 2 4 360 2018
  •  Tethered magnets are the key to magnetotaxis: direct observations of Magnetospirillum magneticum AMB-1 show that MamK distributes magnetosome organelles equally to daughter cells. Taoka, A., Kiyokawa, A., Uesugi, C., Kikuchi, Y., Oestreicher, A., Morii, K., Eguchi, Y., Fukumori, Y. mBio 8 4 e00679-17 2017/08
  •  High-Speed Atomic Force Microscopy Reveals Loss of Nuclear Pore Resilience as a Dying Code in Colorectal Cancer Cells Mohamed MS, Kobayashi A, Taoka A, Watanabe-Nakayama T, Kikuchi Y, Hazawa M, Minamoto T, Fukumori Y, Kodera N, Uchihashi T, Ando T, Wong RW. ACS Nano 11 6 5567-5578 2017/05
  •  Live-Cell Imaging of Bacterial Cells Using High-Speed Atomic Force Microscopy Azuma TAOKA, Yoshihiro FUKUMORI 53 5 293-298 2015/05
  •  A protein-protein interaction in magnetosomes: TPR 1 protein MamA interacts with an Mms6 protein Hoang Viet Nguyen, Emi Suzuki, Zachery Oestreicher, Hiroshi Minamide, Hiroshi Endoh, Yoshihiro Fukumori, Azuma Taoka Biochemistry and Biophysics Reports  7 39–44 2016/09
  •  A comparison of the surface nanostructure from two different types of gram-negative cells: Escherichia coli and Rhodobacter sphaeroides Z.W. Oestreicher, A. Taoka, Y. Fukumori Micron 8-14 72 2015/02
  •  Purification, Characterization, and Crystallization of Crocodylus siamensis Hemoglobin  Jandaruang J., Siritapetawee J., Songsiriritthigul C., Preecharram S., Taoka A., Dhiravisit A., Fukumori Y., Thammasirirak S. The Protein Journal 33 4 377-385 2014/08
  •  Characterization of uncultured giant rod-shaped magnetotactic Gammaproteobacteria from a fresh water pond in Kanazawa, Japan Azuma Taoka, Junya Kondo, Zachery Oestreicher, and Yoshihiro Fukumori MICROBIOLOGY-SGM 160 10 2226-2234 2014/07
  •  A magnetosome-associated cytochrome MamP is critical for magnetite crystal growth during the exponential growth phase Azuma Taoka, Yukako Eguchi, Shingo Mise, Zachery Oestreicher, Fumio Uno and Yoshihiro Fukumori FEMS MICROBIOLOGY LETTERS 358 1 21-29 2014/07
  •  Extranuclear dynamics of 111Ag(→111Cd) doped in AgI nanoparticles W. Sato, R. Mizuuchi, N. Irioka, S. Komatsuda, S. Kawata, A. Taoka, Y. Ohkubo CHEMICAL PHYSICS LETTERS 609 104-107 2014/06
  •  Structure and Function of Magnetotactic Bacterial Organelle “Magnetosome" Fukumori, Y., Taoka, A 54 1 11-14 2014/01
  •  Purification and Characterization of Coacervate-Forming Cuticular Proteins from Papilio xuthus Pupae Masahiro Yamanaka, Yumi Ishizaki, Taro Nakagawa, Azuma Taoka and Yoshihiro Fukumori ZOOLOGICAL SCIENCE 30 7 534-542 2013/07
  •  Analysis of magnetotactic behavior by swimming assay. Sakaguchi Sakaguchi, Taoka Azuma, Fukumori Yoshihiro. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77 5 940-947 2013/05
  •  Single-Molecule Imaging on Living Bacterial Cell Surface by High-Speed AFM Hayato Yamashita†, Azuma Taoka†(共同筆頭著者), Takayuki Uchihashi, Tomoya Asano, Toshio Ando, Yoshihiro Fukumori (†: H.Y. and A.T. contributed equally to this work.) JOURNAL OF MOLECULAR BIOLOGY 422 2 300-309 2012/05
  •  Visualization and structural analysis of the bacterial magnetic organelle magnetosome using atomic force microscopy Yamamoto, D.*, Taoka, A.*(共同筆頭著者), Uchihashi, T., Sasaki, H., Watanabe, H., Ando, T., and Fukumori, Y. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME 107 21  9382-9387 2010/05
  •  Identification of iron transporters expressed in the magnetotactic bacterium Magnetospirillum magnetotacticum. Taoka A, Umeyama C, Fukumori Y. CURRENT MICROBIOLOGY 58 2 177-181 2009/01
  •  Polymerization of the actin-like protein MamK, which is associated with magnetosomes. Taoka, A., Asada, R., Wu, L-F., and Fukumori, Y. JOURNAL OF BACTERIOLOGY 189 23  8737-8740 2007/12
  •  Biosynthesis of magnetite particles in magnetic bacteria Y. Fukumori, A. Taoka 24 12 5-13 2007/12
  •  Participation of nitric oxide reductase in survival of Pseudomonas aeruginosa in LPS-activated macrophages Kakishima, K., Shiratsuchi, A., Taoka, A., Nakanishi, Y., and Fukumori, Y. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2007/04
  •  Strucuture and cellular localization of bacterial magnetic organelle Y. Fukumori, A. Taoka 45 3 154-156 2007/03
  •  Spatial localizations of Mam22 and Mam12 in the magnetosomes of Magnetospirillum magnetotacticum Taoka, A., Asada, R., Sasaki, H., Anzawa, K., Wu, L-F., and Fukumori, Y. JOURNAL OF BACTERIOLOGY 188 11  3805-3512 2006/06
  •  Nitrate reductase from the magnetotactic bacterium Magnetospirillum magnetotacticum MS-1: purification and sequence analyses Taoka, A., Yoshimatsu, K., Kanemori, M., and Fukumori, Y. CANADIAN JOURNAL OF MICROBIOLOGY 49  197-206 2003/05

Conference Presentations

  • Molecular machinery for subcellular positioning of bacterial magnetic organelle(2020/02/19)
  • 細菌のオルガネラ?!: 磁石を作る細菌のユニークな生存戦略(2020/01/23)
  • Molecular machinery for bacterial magnetic organelle positioning(conference:Ames Laboratory Seminar)(2019/09/18)
  • ナノサイズの磁石を作る細菌-磁性細菌の生物学(conference:Berkeley Japanese Academic Network (BJAN) 第55回交流会)(2019/07/19)
  • Analysis of pH regulation in magnetotactic bacteria using pH-sensitive fluorescent protein(2020/02/19)

show all

  • 高速AFMの位相モードを用いた細菌表面物性の生細胞イメージング(2020/02/19)
  • Dynamic molecular imaging on living bacterial cell surface.(2019/04/23)
  • Direct imaging of membrane vesicle-mediated cell-to-cell communication using high-speed AFM(conference:第92回 日本細菌学会総会)(2019/04/23)
  • Imaging of Dynamic Polymerization of Actin-Like Protein MamK for Bacterial Organelle Magnetosome Positioning.(conference:ASM microbe 2019)(2019/06/20)

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「分子イメージングによる原核細胞のナノオルガネラ制御機構の解明」(2019-2021) 
○「磁性細菌細胞内で新規に合成された磁気オルガネラと細胞骨格の相互作用」(2018-2020) 
○「原核細胞の細胞骨格による磁気感知オルガネラ配置の分子機構」(2016-2018) 
○「磁性細菌の磁気微粒子合成に関わる新奇ヘム蛋白質の機能解明」(2013-2015) 
○「「磁場」を感知するバクテリアの磁気オルガネラを支える細胞骨格」(2011-2012) 
○「原核細胞の磁気オルガネラの生細胞イメージングー形成・機能メカニズムの解明ー」(2010-2012) 

Classes (Bachelors)

○Biochemistry Lab(2019)
○Research Work in Biology (2) B(2019)
○Advanced Biology Lab(2019)
○Group Seminar of Biology(2019)
○Guide to Biology and Bioengineering A(2019)
○Research Work in Biology (2) A(2019)
○Research Work in Biology (1) B(2019)
○Research Work in Biology (1) A(2019)
○Research Seminar in Biology (2) B(2019)
○Research Seminar in Biology (2) A(2019)
○Research Seminar in Biology (1) B(2019)
○Research Seminar in Biology (1) A(2019)
○Biochemistry Seminar A(2019)
○Biochemistry B(2019)
○Molecular and Cellular Biology(2019)
○Biochemistry Seminar B(2019)
○Molecular and Cellular Biology(2018)
○Biochemistry Seminar B(2018)
○Biochemistry Seminar A(2018)
○Research Work in Biology(1)(2018)
○Research Seminar in Biology (2)(2018)
○Research Seminar in Biology (1)(2018)
○Biochemistry Lab(2018)
○Experiments in Biology(2018)
○GS English Language for Undergraduates I (English for Science and Engineering)(2018)
○GS English Language for Undergraduates II (English for Science and Engineering)(2018)
○Group Seminar of Biology(2018)
○Basic Biology Lab(2018)
○Advanced Biology Lab(2018)
○Topics in Biology and Bioengineering A(2018)
○Guide to Biology and Bioengineering A(2018)
○Research Work in Biology(2)(2018)
○Biochemistry Seminar(2017)
○Biochemistry Lab(2017)
○Research Seminar in Biology (1)(2017)
○GS English Language for Undergraduates I (English for Science and Engineering)(2017)
○Guide to Biology and Earth Sciences(2017)
○Basic Biology Lab(2017)
○Research Seminar in Biology (2)(2017)
○Research Work in Biology(1)(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Molecular and Cellular Biology(2017)
○Experiments in Biology(2017)
○GS English Language for Undergraduates II (English for Science and Engineering)(2017)
○Group Seminar of Biology(2017)
○Research Work in Biology(2)(2017)
○Advanced Biology Lab(2017)
○Molecular and Cellular Biology(2016)
○Molecular and Cellular Biology(2016)
○Molecular and Cellular Biology(2016)
○Experiments in Biology(2016)
○Biochemistry Seminar(2016)
○Biochemistry Lab(2016)
○Research Work in Biology(2)(2016)
○Research Work in Biology(1)(2016)
○Research Seminar in Biology (2)(2016)
○Research Seminar in Biology (1)(2016)
○Experiments in Biology(2016)

Classes (Graduate Schools)

○Exercise in Systems Biology 2B(2019)
○Exercise in Systems Biology 2A(2019)
○Exercise in Systems Biology 1B(2019)
○Exercise in Systems Biology 1A(2019)
○Basic Exercise in Systems Biology(2019)
○Research work in Systems Biology(2019)
○Research Skills B(2018)
○Research Skills A(2018)
○Research work in Systems Biology(2018)
○Basic Exercise in Systems Biology(2018)
○Systems structure and function in biomolecules B(2018)
○Exercise in Systems Biology 2B(2018)
○Exercise in Systems Biology 2A(2018)
○Exercise in Systems Biology 1B(2018)
○Exercise in Systems Biology 1A(2018)
○Basic Systems Biology B(2018)
○Basic Systems Biology A(2018)
○Molecular Microbiology(2018)
○Systems structure and function in biomolecules B(2017)
○Basic Exercise in Systems Biology(2017)
○Exercise in Systems Biology 1A(2017)
○Exercise in Systems Biology 1B(2017)
○Exercise in Systems Biology 2A(2017)
○Exercise in Systems Biology 2B(2017)
○Research Skills B(2017)
○Research Skills A(2017)
○Systems structure and function in biomolecules(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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