Jump to contents

Researcher Information

last modified:2023/03/22

Assistant Professor YOSHIDA, Takeshi

Faculty, Affiliation

WPI Nano Life Science Institute

College and School Educational Field


Department of Immunology

Academic Background


Year & Month of Birth

Academic Society




Speciality Keywords

Research Themes



  •  Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis. Takahashi A, Komiya E, Kakutani H, Yoshida T, Fujii M, Horiguchi Y, Mizuguchi H, Tsutsumi Y, Tsunoda S, Koizumi N, Isoda K, Yagi K, Watanabe Y, Kondoh M. Biochemical pharmacology 75 8 1639-1648 2008/01/05
  •  Targeting tight junction proteins-significance for drug development. Kondoh M, Yoshida T, Kakutani H, Yagi K Drug discovery today. 13 3-4 180-186 2008/01/10
  •  Evaluation of promoter strength in mouse and rat primary hepatocytes using adenovirus vectors. Arita E, Kondoh M, Isoda K, Nishimori H, Yoshida T, Mizuguchi H, Yagi K. European journal of pharmaceutics and biopharmaceutics  70 1 1-6 2008/05/29
  •  Promising targets for anti-hepatitis C virus agents. Yoshida T, Kondoh M, Yagi K. Current medicinal chemistry 18 8 1239-1244 2011
  •  Adenovirus vector-mediated assay system for hepatitis C virus replication. Yoshida T, Kondoh M, Ojima M, Mizuguchi H, Yamagishi Y, Sakamoto N, Yagi K. Nucleic acids research 39 10 e64 2011/02/08

show all

  •  Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection. Yoshida T, Takayama K, Kondoh M, Sakurai F, Tani H, Sakamoto N, Matsuura Y, Mizuguchi H, Yagi K. Biochemical and biophysical research communications 416 1-2 119-124 2011/11/10
  •  Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a. Sakurai F, Furukawa N, Higuchi M, Okamoto S, Ono K, Yoshida T, Kondoh M, Yagi K, Sakamoto N, Katayama K, Mizuguchi H. Virus research 165 2 214-218 2012/02/10
  •  Development of an adenovirus vector containing a hepatitis C virus expression cassette and its application Yoshida T, Kondoh M, Mizuguchi H, Yagi K. Journal of the Pharmaceutical Society of Japan 133 3 305-311 2013
  •  A baculoviral display system to assay viral entry. Iida M, Yoshida T, Watari A, Yagi K, Hamakubo T, Kondoh M. Biological & pharmaceutical bulletin 36 11 1867-1869 2013
  •  A novel affinity-based method for the isolation of highly purified extracellular vesicles.  Nakai W, Yoshida T, Diez D, Miyatake Y, Nishibu T, Imawaka N, Naruse K, Sadamura Y, Hanayama R. Scientific reports 6 33935 2016/09/23
  •  Induction of Live Cell Phagocytosis by a Specific Combination of Inflammatory Stimuli. Takamasa Ishidome, Takeshi Yoshida, Rikinari Hanayama EBioMedicine 22 89-99 2017/07/13

Conference Presentations

  • Development of a Conventional Assay System for HCV Replication Using RNA Polymerase I-dependent Expression Plasmid.(conference:The American Society for Cell Biology 48th Annual Meeting)(2008/12/13)
  • Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay.(conference:The 18th International Symposium on Hepatitis C Virus and Related Viruses)(2011/09/08)
  • A high-throughput screening method for the identification of key molecules that mediate exosome secretion.(conference:The 2nd NIF Winter School on Advanced Immunology)(2013/01/20)
  • Discharge of anti-tumor drug via exosomes(2016/08/31)


Arts and Fieldwork


Theme to the desired joint research

Grant-in-Aid for Scientific Research

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

To Page Top