last modified：2025/12/05
Assistant Professor Hariba Tomoyoshi
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences Forensic medicine
Assistant professor
College and School Educational Field
Graduate School of Medical Science
Laboratory
TEL:076-265-2224
Academic Background
【Academic background(Doctoral/Master's Degree)】
Gunma University Doctor Completed
Career
Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences Faculty of Medicine Assistant professor(2024/04-)
Tokyo University of Science(2023/04-2024/04)
Takasaki University of Health and Welfare postdoctoral researcher(2021/04-2023/03)
Takasaki University of Health and Welfare Research assistant(2019/07-2021/03)
Gunma University Graduate School of Medicine Diagnostic Radiology and Nuclear Medicine researcher(2018/11-2021/03)
(2013/10-2014/09)
(2010/10-2013/09)
Year & Month of Birth
1987/04
Academic Society
Japanese Society of Legal Medicine
Japanese Association of Suicide Prevention
American Association for the Advancement of Science
Award
American Association for the Advancement of Science
American Association for the Advancement of Science
American Association for the Advancement of Science
○Japan Radiological Society English Poster Session Awards(2019/10)
Specialities
Legal medicine、Medical pharmacy、Radiation science、General internal medicine (including psychosomatic medicine)
Speciality Keywords
P-gp,Diagnosis of drowning,EMT
Research Themes
Books
Papers
- Strontium concentration in body cavity fluids as a novel marker for drowning diagnosis and entry site determination. Ryota Nakanishi,Takahiro Eida,Tomoyoshi Hariba,Satoru Minabe,Asami S Mashio,Takaya Murakami,Hiroshi Hasegawa,Masahiko Zuka Legal medicine 75 102616 2025/04/02
- Analysis of Protein Digestion and Absorption Using a Ussing Chamber to Simulate the Environment in the Digestive Tract. Tomoyoshi Hariba,Minami Kaneko,Wangyang Liu,Oyadeyi Ayodele Stephen,Kentaro Nakamura,Maki Yamaguchi,Chigusa Yoshida,Tokiko Oishi,Shoko Kobayashi,Kenta Mizoi,Takuo Ogihara Journal of Nutritional Science and Vitaminology 70 2 158 2024/04/30
- Clinical Analysis and in Vitro Correlation of BCRP-Mediated Drug-Drug Interaction in the Gastrointestinal Tract Liyanage Manosika Buddhini Perera,Kenzo Okazaki,Yunje Woo,Saori Takahashi,Xieyi Zhang,Kenta Mizoi,Toshinari Takahashi,Takuo Ogihara Biological and Pharmaceutical Bulletin 47 4 750 2024/04/01
- Mechanism of Induction of P-gp Activity During MET Induced by DEX in Lung Cancer Cell Line. Wangyang Liu,Xieyi Zhang,Hiroki Sunakawa,Liyanage Manosika Buddhini Perera,Larasati Martha,Kenta Mizoi,Takuo Ogihara Journal of pharmaceutical sciences 2024/03/01
- Evaluation of Various Cryoablation Protocols in Multiple Cell 1ines using Quantitative Biomarkers of Bioluminescence Imaging: An in vitro Study Bolortuya Khurelbaatar,A. Adhipatria P. Kartamihardja,Masaya Miyazaki,Oyunbold Lamid-Ochir,Xieyi Zhang,Takahito Nakajima,Yoshito Tsushima The Kitakanto Medical Journal 74 1 21 2024/02/01
- Transporter and metabolic enzyme-mediated intra-enteric circulation of SN-38, an active metabolite of irinotecan: A new concept. Larasati Martha,Akane Nakata,Shinnosuke Furuya,Wangyang Liu,Xieyi Zhang,Kenta Mizoi,Takuo Ogihara Biochemical and biophysical research communications 665 19 2023/04/28
- Inhibitory Effect of Calcium Alginate on Postprandial Blood Glucose Elevation in Rats
51 4 477-481 2023/04/20
- Slug Mediates MRP2 Expression in Non-Small Cell Lung Cancer Cells Xieyi Zhang,Wangyang Liu,Kazue Edaki,Yuta Nakazawa,Saori Takahashi,Hiroki Sunakawa,Kenta Mizoi,Takuo Ogihara Biomolecules 12 6 806 2022/06/09
- P-glycoprotein–mediated pharmacokinetic interactions increase pimozide hERG channel inhibition Hiroki Morishita,Liyanage Manosika Buddhini Perera,Xieyi Zhang,Kenta Mizoi,Masa-aki Ito,Kentaro Yano,Takuo Ogihara Journal of Pharmaceutical Sciences 111 12 3411 2022/09
- A lightweight 0.25 mm lead equivalence protective apron for shielding radiological technologists from radiation exposure during single-photon emission computed tomography in nuclear medicine Takao Kanzaki,Tetsuya Higuchi,Xieyi Zhang,Yasuyuki Takahashi,Mari Sakai,Yoshito Tsushima Radioprotection 57 2 143 2022/04
- Correlations of mRNA Levels among Efflux Transporters, Transcriptional Regulators, and Scaffold Proteins in Non-Small-Cell Lung Cancer Xieyi Zhang,Wangyang Liu,Kazue Edaki,Yuta Nakazawa,Hiroki Kamioka,Atsushi Fujita,Ryoichi Onozato,Misa Iijima,Shigeru Tsuchida,Takahiro Arai,Yukiyoshi Fujita,Kenta Mizoi,Takuo Ogihara CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY 2021 4005327 2021/11
- Imaging modalities for monitoring acute therapeutic effects after near-infrared photoimmunotherapy in vivo. Xieyi Zhang,Takahito Nakajima,Kenta Mizoi,Yoshito Tsushima,Takuo Ogihara Journal of biophotonics 15 1 e202100266 2021/11/15
- Effect of metformin on 18F-fluorodeoxyglucose uptake and positron emission tomographic imaging. Xieyi Zhang,Takuo Ogihara,Min Zhu,Dolgormaa Gantumur,Yang Li,Kenta Mizoi,Hiroki Kamioka,Yoshito Tsushima The British journal of radiology 95 1130 20200810 2021/10/27
- Moesin-Mediated P-Glycoprotein Activation During Snail-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells Hiroki Kamioka,Takumi Tomono,Atsushi Fujita,Ryoichi Onozato,Misa Iijima,Shigeru Tsuchida,Takahiro Arai,Yukiyoshi Fujita,Xieyi Zhang,Kentaro Yano,Takuo Ogihara Journal of Pharmaceutical Sciences 109 7 2302 2020/07
- Early detection of progressive disease using thyroglobulin doubling-time in metastatic differentiated thyroid carcinoma treated with radioactive iodine. Xieyi Zhang,Tetsuya Higuchi,Hiroyasu Tomonaga,Oyunbold Lamid-Ochir,Anu Bhattarai,Huong Nguyen-Thu,Ayako Taketomi-Takahashi,Hiromi Hirasawa,Yoshito Tsushima Nuclear medicine communications 41 4 350 2020/04
- Evaluation of a Correction Method for 111In-Pentetreotide SPECT Imaging of Gastroenteropancreatic Neuroendocrine Tumors. Takao Kanzaki,Yasuyuki Takahashi,Tetsuya Higuchi,Xieyi Zhang,Nao Mogi,Takayuki Suto,Yoshito Tsushima Journal of nuclear medicine technology 48 4 326 2020/12
- Bioluminescence Image as a Quantitative Imaging Biomarker for Preclinical Evaluation of Cryoablation in a Murine Model Oyunbold Lamid-Ochir,Takahito Nakajima,Masaya Miyazaki,Xieyi Zhang,Khongorzul Erdene,Takashi Murakami,Yoshito Tsushima JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY 29 7 1034 2018/07
- Detection of epidermal growth factor receptor expressing lung squamous cell carcinoma by activatable fluorescence imaging Xieyi Zhang,Takahito Nakajima,Mai Kim,Aiko Yamaguchi,Oyunbold Lamid-Ochir,Huong Nguyen Thu,Yoshito Tsushima JOURNAL OF NUCLEAR MEDICINE 59 2018/05
- Activatable fluorescence detection of epidermal growth factor receptor positive mediastinal lymph nodes in murine lung cancer model. Xieyi Zhang,Takahito Nakajima,Mai Kim,Aiko Yamaguchi,Oyunbold Lamid-Ochir,Huong Nguyen-Thu,Anu Bhattarai,Hirofumi Hanaoka,Yoshito Tsushima PloS one 13 6 e0198224 2018
- Can 18F-fluorodeoxyglucose positron emission tomography predict the response to radioactive iodine therapy in metastatic differentiated thyroid carcinoma? Xieyi Zhang,Tetsuya Higuchi,Arifudin Achmad,Anu Bhattarai,Hiroyasu Tomonaga,Huong Nguyen Thu,Aiko Yamaguchi,Hiromi Hirasawa,Ayako Taketomi-Takahashi,Yoshito Tsushima European Journal of Hybrid Imaging 2 1 2018/12/01
Conference Presentations
- Analysis of drug-endogenous substrate interactions using in vitro and in vivo methods(conference：39th JSSX and 26th North American ISSX Meeting)(2024/09/15)
- Regulation of P-glycoprotein expression and role of ERM proteins in lung cancer cell metastasis(conference：39th JSSX and 26th North American ISSX Meeting)(2024/09/15)
- 動物的蛍光イメージングによるEGFR陽性肺扁平上皮癌の検出(Detection of EGFR Positive Lung Squamous Cell Carcinoma by Dynamic Fluorescence Imaging)(conference：The Kitakanto Medical Journal)(2016/08)
- 分化型甲状腺癌におけるサイログロブリンの倍加時間に関する動的モニタリングの価値(The Value of Dynamic Monitoring of Thyroglobulin Doubling Time in Differentiated Thyroid Carcinoma)(conference：日本医学放射線学会学術集会抄録集)(2018/02)
- RAIで治療した転移性DTCにおけるTgDTを用いたPDの早期検出(Early detection of PD using TgDT in metastatic DTC treated with RAI)(conference：日本医学放射線学会秋季臨床大会抄録集)(2019/09)
- SUVmax May Predict the Therapeutic Response to 131I Radioactive Iodine Therapy in Metastatic Differentiated Thyroid Carcinoma: A Case Report(conference：群馬県核医学研究会会誌)(2019)
- The 18F-FDG PET value for prediction of radioiodine treatment response in metastatic differentiated thyroid cancer(conference：核医学(Web))(2016)
- 18F FDG PETは転移性分化型甲状腺癌における131I放射性ヨウ素の治療反応を予測できるか?(Can 18F FDG PET Predict 131I Radioiodine Therapeutic Response in Metastatic Differentiated Thyroid Carcinoma?)(conference：The Kitakanto Medical Journal)(2017/08)
- In vivoにおいて光免疫療法後の急性治療効果を評価する画像検査(Imaging Modalities for Evaluating Acute Therapeutic Effects after Photoimmunotherapy in Vivo)(conference：日本医学放射線学会学術集会抄録集)(2017/02)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「P-糖タンパク質の一塩基多型とその基質認識性の違いの解明 」(2025-2027)
○「肺がん転移時の間葉上皮転換過程における薬剤耐性の変動とそのメカニズムの解明」(2022-2024)
○「肺がんの転移に関与する転写調節因子による薬物耐性獲得メカニズムの解明」(2020-2021)
○「脳脊髄液中バイオマーカーによる脳動脈瘤成長および頭蓋内組織脆弱性の解析」(2025-2027)
○「難治性リンパ腫における膜タンパク複合体形成の同定とその阻害の有用性評価」(2025-2027)
○「膜タンパクの局在制御に基づくがん悪性化克服法の研究」(2022-2024)