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last modified：2025/04/02
Professor KIKUCHI Mitsuru
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences Department of Psychiatry & Behavioral Science
Professor
College and School Educational Field
Division of Medicine, Graduate School of Medical Science
United Graduate School of Child Depelopment
School of Medicine, College of Medical, Pharmaceutical and Health Sciences
Laboratory
TEL: FAX:
Academic Background
【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor 199906 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University 199403
【Degree】
MD
Career
Kanazawa University(2019-)
Kanazawa University (2011-2019)
Kanazawa University Department of psychiatry(2005-2011)
University Hospital of Psychiatry Bern(2004-2005)
Kanazawa University(2002-2004)
Komatsu Municipal Hospital Department of psychiatry(1999-2002)
National Hospital Organization Hokuriku Hospital Department of psychiatry(1998-1998)
FUKUI PREFECTURAL HOSPITAL Department of psychiatry(1996-1997)
NOTO General Hospital (1995-1996)
Kanazawa University (1994-1995)
Year & Month of Birth
1968/07
Academic Society
The Japanese Society of Psychiatry and Neurology
The Japanese Society for Child and Adolescent Psychiatiry
Japanese Society of Clinical Neurophysiology
International Society for the Advancement of Clinical MEG.
Japanese Pharmarco-EEG Society
Award
Specialities
Neurophysiology/General neuroscience、Psychiatric science
Speciality Keywords
Psychiatry, Neurophysiology
Research Themes
Research on children with developmental disabilities using infant MEG and wearable sensors.
In collaboration with the Research Center for Child Mental Development at our university, we are working on elucidating the mechanisms that cause the diversity of ASD, focusing on social impairment, vision, hearing, somatosensory perception, motor function, and sleep in autism spectrum disorder (ASD). Because of the diversity of ASD, physiological studies based on ASD diagnosis have not been able to fully explain it. We have conducted behavioral assessment of diversity, sleep assessment using the latest wearable sensors, and brain feature assessment using magnetoencephalography for infants. By doing so, we are trying to elucidate the pathological mechanism of ASD based on the phenotypic diversity of ASD, which is not bound by the conventional wisdom.
Neurophysiological study on schizophrenia
I explain the pathophysiology of schizophrenia using brain waves and other methods. Specifically, I focus on searching for physiological indications that could be useful for early judgment of treatment effect.
Neuromodulation by transcranial direct current electrical stimulation (tDCS)
Pathophysiology of anxiety disorders
Books
- Mitsuru Kikuchi,Yuko Yoshimura Handbook of Pediatric Brain Imaging: Methods and Applications (Volume 2) Academic Press 2021/10
Papers
- Markers for the central serotonin system correlate to verbal ability and paralinguistic social voice processing in autism spectrum disorder Yoshimura Y, Kikuchi M, Saito DN, Hirosawa T, Takahashi T, Munesue T, Kosaka H, Naito N, Ouchi Y, Minabe Y. Sci Rep. 10 1 14558 2020/09
- Optimal robot for intervention for individuals with autism spectrum disorders Kumazaki H, Muramatsu T, Yoshikawa Y, Matsumoto Y, Ishiguro H, Kikuchi M, Sumiyoshi T, Mimura M. Psychiatry Clin Neurosci. Online ahead of print 2020/08
- Different associations between intelligence and social cognition in children with and without autism spectrum disorders Hirosawa T, Kontani K, Fukai M, Kameya M, Soma D, Hino S, Kitamura T, Hasegawa C, An KM, Takahashi T, Yoshimura Y, Kikuchi M. PLoS One. 15 8 2020/08
- Neural Decoding of Multi-Modal Imagery Behavior Focusing on Temporal Complexity Furutani N, Nariya Y, Takahashi T, Ito H, Yoshimura Y, Hiraishi H, Hasegawa C, Ikeda T, Kikuchi M. Front Psychiatry. 11 746 2020/07
- Competitiveness and individual characteristics: a double-blind placebo-controlled study using oxytocin Kurokawa H, Kinari Y, Okudaira H, Tsubouchi K, Sai Y, Kikuchi M, Higashida H, Ohtake F. Sci Rep. 10 1 2020/07
- Intake of ω-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases Yamashima T, Ota T, Mizukoshi E, Nakamura H, Yamamoto Y, Kikuchi M, Yamashita T, Kaneko S. Adv Nutr. Online ahead of print. 2020/07
- Relationship between epileptiform discharges and social reciprocity or cognitive function in children with and without autism spectrum disorders: an MEG study. Hirosawa T, Sowman PF, Fukai M, Kameya M, Soma D, Hino S, Kitamura T, An KM, Yoshimura Y, Hasegawa C, Saito D, Ikeda T, Kikuchi M. Psychiatry Clin Neurosci. Online ahead of print. 2020/06
- Sustaining temporal attention prevents habit expression during operant learning in rats. Lin Z, Nishikawa H, Iguchi Y, Iwanami A, Kikuchi M, Toda S. Sci Rep. 10 1 10303 2020/06
- The Maturation of the P1m Component in Response to Voice From Infancy to 3 Years of Age: A Longitudinal Study in Young Children Yoshimura Y, Hasegawa C, Ikeda T, Saito DN, Hiraishi H, Takahashi T, Kumazaki H, Kikuchi M. Brain Behav. Online ahead of print 2020/06
- Spontaneous MEG Activity of the Cerebral Cortex During Eyes Closed and Open Discriminates Alzheimer's Disease From Cognitively Normal Older Adults Ikeda Y, Kikuchi M, Noguchi-Shinohara M, Iwasa K, Kameya M, Hirosawa T, Yoshita M, Ono K, Samuraki-Yokohama M, Yamada M. Sci Rep. 10 1 9132 2020/06
- Auditory Steady-State Response at 20 Hz and 40 Hz in Young Typically Developing Children and Children With Autism Spectrum Disorder Ono Y, Kudoh K, Ikeda T, Takahashi T, Yoshimura Y, Minabe Y, Kikuchi M. Psychiatry Clin Neurosci. 74 6 354-361 2020/06
- Brain Responses to Human-Voice Processing Predict Child Development and Intelligence An KM, Hasegawa C, Hirosawa T, Tanaka S, Saito DN, Kumazaki H, Yaoi K, Kikuchi M, Yoshimura Y. Hum Brain Mapp 41 9 2292-2301 2020/06
- Brief Report: Odour Awareness in Young Children With Autism Spectrum Disorders Kumazaki H, Okamoto M, Yoshimura Y, Ikeda T, Hasegawa C, Saito DN, Iwanaga R, Tomiyama S, An KM, Minabe Y, Kikuchi M. J Autism Dev Disord. 50 5 1809-1815 2020/05
- Classification Methods Based on Complexity and Synchronization of Electroencephalography Signals in Alzheimer's Disease Nobukawa S, Yamanishi T, Kasakawa S, Nishimura H, Kikuchi M, Takahashi T. Front Psychiatry . 11 255 2020/04
- Developmental Changes in Attention to Social Information From Childhood to Adolescence in Autism Spectrum Disorders: A Comparative Study Fujioka T, Tsuchiya KJ, Saito M, Hirano Y, Matsuo M, Kikuchi M, Maegaki Y, Choi D, Kato S, Yoshida T, Yoshimura Y, Ooba S, Mizuno Y, Takiguchi S, Matsuzaki H, Tomoda A, Shudo K, Ninomiya M, Katayama T, Kosaka H. Mol Autism. 11 1 24 2020/04
- Feasibility of Autism-Focused Public Speech Training Using a Simple Virtual Audience for Autism Spectrum Disorder Kumazaki H, Muramatsu T, Kobayashi K, Watanabe T, Terada K, Higashida H, Yuhi T, Mimura M, Kikuchi M. Psychiatry Clin Neurosci. 74 2 124-131 2020/02
- Brief Report: Olfactory Adaptation in Children With Autism Spectrum Disorders Kumazaki H, Muramatsu T, Miyao M, Okada KI, Mimura M, Kikuchi M. J Autism Dev Disord. 49 8 3462-3469 2019/08
- Job Interview Training Targeting Nonverbal Communication Using an Android Robot for Individuals With Autism Spectrum Disorder Kumazaki H, Muramatsu T, Yoshikawa Y, Corbett BA, Matsumoto Y, Higashida H, Yuhi T, Ishiguro H, Mimura M, Kikuchi M. Autism. 23 6 1586-1595 2019/08
- How the Realism of Robot Is Needed for Individuals With Autism Spectrum Disorders in an Interview Setting Kumazaki H, Muramatsu T, Yoshikawa Y, Matsumoto Y, Miyao M, Ishiguro H, Mimura M, Minabe Y, Kikuchi M. Front Psychiatry. 10 486 2019/07
- Comedic Experience With Two Robots Aided a Child With Autism Spectrum Disorder to Realize the Importance of Nonverbal Communication Kumazaki H, Muramatsu T, Yoshikawa Y, Matsumoto Y, Ishiguro H, Sumiyoshi T, Mimura M, Kikuchi M. Psychiatry Clin Neurosci. 73 7 423 2019/07
- Relaxing Gaze Aversion of Adolescents With Autism Spectrum Disorder in Consecutive Conversations With Human and Android Robot-A Preliminary Study Yoshikawa Y, Kumazaki H, Matsumoto Y, Miyao M, Kikuchi M, Ishiguro H. Front Psychiatry. 10 370 2019/06
- Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect Ikeda M, Takahashi A, Kamatani Y, Momozawa Y, Saito T, Kondo K, Shimasaki A, Kawase K, Sakusabe T, Iwayama Y, Toyota T, Wakuda T, Kikuchi M, Kanahara N, Yamamori H, Yasuda Y, Watanabe Y, Hoya S, Aleksic B, Kushima I, Arai H, Takaki M, Hattori K, Kunugi H, Okahisa Y, Ohnuma T, Ozaki N, Someya T, Hashimoto R, Yoshikawa T, Kubo M, Iwata N. Schizophr Bull. 45 4 824-834 2019/06
- Atypical Body Movements During Night in Young Children With Autism Spectrum Disorder: A Pilot Study Naito N, Kikuchi M, Yoshimura Y, Kumazaki H, Kitagawa S, Ikeda T, Hasegawa C, Saito DN, Tomiyama S, Minabe Y. Sci Rep. 9 1 6999 2019/05
- Anodal Transcranial Direct Current Stimulation Induces High Gamma-Band Activity in the Left Dorsolateral Prefrontal Cortex During a Working Memory Task: A Double-Blind, Randomized, Crossover Study Ikeda T, Takahashi T, Hiraishi H, Saito DN, Kikuchi M. Front Hum Neurosci. 13 136 2019/04
- Role-Play-Based Guidance for Job Interviews Using an Android Robot for Individuals With Autism Spectrum Disorders Kumazaki H, Muramatsu T, Yoshikawa Y, Matsumoto Y, Ishiguro H, Mimura M, Kikuchi M. Front Psychiatry. 10 239 2019/04
- Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots Kumazaki H, Muramatsu T, Yoshikawa Y, Yoshimura Y, Ikeda T, Hasegawa C, Saito DN, Shimaya J, Ishiguro H, Mimura M, Kikuchi M. J Autism Dev Disord. 49 4 1709-1716 2019/04
- Brief Report: Evaluating the Utility of Varied Technological Agents to Elicit Social Attention From Children With Autism Spectrum Disorders Kumazaki H, Warren Z, Swanson A, Yoshikawa Y, Matsumoto Y, Yoshimura Y, Shimaya J, Ishiguro H, Sarkar N, Wade J, Mimura M, Minabe Y, Kikuchi M. J Autism Dev Disord. 49 4 1700-1708 2019/04
- Endogenous Dopamine Release Under Transcranial Direct-Current Stimulation Governs Enhanced Attention: A Study With Positron Emission Tomography Fukai M, Bunai T, Hirosawa T, Kikuchi M, Ito S, Minabe Y, Ouchi Y. Transl Psychiatry. 9 1 115 2019/03
- Changes in Functional Connectivity Dynamics With Aging: A Dynamical Phase Synchronization Approach Nobukawa S, Kikuchi M, Takahashi T. Neuroimage. 188 357-368 2019/03
- Social Interaction Improved by Oxytocin in the Subclass of Autism With Comorbid Intellectual Disabilities Higashida H, Munesue T, Kosaka H, Yamasue H, Yokoyama S, Kikuchi M. Diseases. 7 1 24 2019/02
- Atypical Temporal-Scale-Specific Fractal Changes in Alzheimer's Disease EEG and Their Relevance to Cognitive Decline Nobukawa S, Yamanishi T, Nishimura H, Wada Y, Kikuchi M, Takahashi T. Cogn Neurodyn. 13 1 1-11 2019/02
- Oxytocin and excitation/inhibition Balance in Social Recognition Lopatina OL, Komleva YK, Gorina YV, Olovyannikova RY, Trufanova LV, Hashimoto T, Takahashi T, Kikuchi M, Minabe Y, Higashida H, Salmina AB. Neuropeptides. 72 1-11 2018/12
- Association Between Magnetoencephalographic Interictal Epileptiform Discharge and Cognitive Function in Young Children With Typical Development and With Autism Spectrum Disorders Hirosawa T, Kikuchi M, Fukai M, Hino S, Kitamura T, An KM, Sowman P, Takahashi T, Yoshimura Y, Miyagishi Y, Minabe Y. Front Psychiatry. 9 568 2018/11
- Longitudinal Changes in the Mismatch Field Evoked by an Empathic Voice Reflect Changes in the Empathy Quotient in Autism Spectrum Disorder Yoshimura Y, Kikuchi M, Hiraishi H, Hasegawa C, Hirosawa T, Takahashi T, Munesue T, Kosaka H, Hiagashida H, Minabe Y. Psychiatry Res Neuroimaging. 281 117-122 2018/11
- The Impact of Robotic Intervention on Joint Attention in Children With Autism Spectrum Disorders Kumazaki H, Yoshikawa Y, Yoshimura Y, Ikeda T, Hasegawa C, Saito DN, Tomiyama S, An KM, Shimaya J, Ishiguro H, Matsumoto Y, Minabe Y, Kikuchi M. Mol Autism. 9 46 2018/09
- Altered Gamma Oscillations During Motor Control in Children With Autism Spectrum Disorder An KM, Ikeda T, Yoshimura Y, Hasegawa C, Saito DN, Kumazaki H, Hirosawa T, Minabe Y, Kikuchi M. J Neurosci. 38 36 7878-7886 2018/09
- Developmental Trajectory of Infant Brain Signal Variability: A Longitudinal Pilot Study Hasegawa C, Takahashi T, Yoshimura Y, Nobukawa S, Ikeda T, Saito DN, Kumazaki H, Minabe Y, Kikuchi M. Front Neurosci. 12 566 2018/08
- Changes in Maternal Feelings for Children With Autism Spectrum Disorder After Childbirth: The Impact of Knowledge About the Disorder Tomiyama S, Kikuchi M, Yoshimura Y, Hasegawa C, Ikeda T, Saito DN, Kumazaki H, Naito N, Minabe Y. PLoS One. 13 8 e0201862 2018/08
- Relationship Between Odor Identification and Visual Distractors in Children With Autism Spectrum Disorders Kumazaki H, Kikuchi M, Yoshimura Y, Miyao M, Okada KI, Mimura M, Minabe Y. J Autism Dev Disord. 48 7 2590-2592 2018/07
- Gamma-band Auditory Steady-State Response After Frontal tDCS: A Double-Blind, Randomized, Crossover Study Miyagishi Y, Ikeda T, Takahashi T, Kudo K, Morise H, Minabe Y, Kikuchi M. PLoS One. 13 2 e0193422 2018/02
- Can Robotic Systems Promote Self-Disclosure in Adolescents With Autism Spectrum Disorder? A Pilot Study Kumazaki H, Warren Z, Swanson A, Yoshikawa Y, Matsumoto Y, Takahashi H, Sarkar N, Ishiguro H, Mimura M, Minabe Y, Kikuchi M. Front Psychiatry. 9 36 2018/02
- Impressions of Humanness for Android Robot May Represent an Endophenotype for Autism Spectrum Disorders Kumazaki H, Warren Z, Swanson A, Yoshikawa Y, Matsumoto Y, Ishiguro H, Sarkar N, Minabe Y, Kikuchi M. J Autism Dev Disord. 48 2 632-634 2018/02
- Association Studies of WD Repeat Domain 3 and Chitobiosyldiphosphodolichol Beta-Mannosyltransferase Genes With Schizophrenia in a Japanese Population Kobayashi M, Jitoku D, Iwayama Y, Yamamoto N, Toyota T, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T. PLoS One. 13 1 e0190991 2018/01
- Abnormal Functional Connectivity of High-Frequency Rhythms in drug-naïve Schizophrenia Takahashi T, Goto T, Nobukawa S, Tanaka Y, Kikuchi M, Higashima M, Wada Y. Clin Neurophysiol. 129 1 222-231 2018/01
- Approaches for Assessing Olfaction in Children With Autism Spectrum Disorder Kumazaki H, Okamoto M, Kanzaki S, Okada KI, Mimura M, Minabe Y, Kikuchi M. Methods Mol Biol. 1820 221-228 2018
- Altered Human Voice Processing in the Frontal Cortex and a Developmental Language Delay in 3- To 5-year-old Children With Autism Spectrum Disorder Yoshimura Y, Kikuchi M, Hayashi N, Hiraishi H, Hasegawa C, Takahashi T, Oi M, Remijn GB, Ikeda T, Saito DN, Kumazaki H, Minabe Y. Sci Rep. 7 1 17116 2017/12
- Genetic and Molecular Risk Factors Within the Newly Identified Primate-Specific Exon of the SAP97/DLG1 Gene in the 3q29 Schizophrenia-Associated Locus Uezato A, Yamamoto N, Jitoku D, Haramo E, Hiraaki E, Iwayama Y, Toyota T, Umino M, Umino A, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T. Am J Med Genet B Neuropsychiatr Genet. 174 8 798-807 2017/12
- A Pilot Study for Robot Appearance Preferences Among High-Functioning Individuals With Autism Spectrum Disorder: Implications for Therapeutic Use Kumazaki H, Warren Z, Muramatsu T, Yoshikawa Y, Matsumoto Y, Miyao M, Nakano M, Mizushima S, Wakita Y, Ishiguro H, Mimura M, Minabe Y, Kikuchi M. PLoS One. 12 10 e0186581 2017/10
- Quantitative Aspects of Communicative Impairment Ascertained in a Large National Survey of Japanese Children Oi M, Fujino H, Tsukidate N, Kamio Y, Yoshimura Y, Kikuchi M, Hasegawa C, Gondou K, Matsui T. J Autism Dev Disord. 47 10 3040-3048 2017/10
- Android Robot-Mediated Mock Job Interview Sessions for Young Adults With Autism Spectrum Disorder: A Pilot Study Kumazaki H, Warren Z, Corbett BA, Yoshikawa Y, Matsumoto Y, Higashida H, Yuhi T, Ikeda T, Ishiguro H, Kikuchi M. Front Psychiatry. 8 169 2017/09
- Detection of Atypical Network Development Patterns in Children With Autism Spectrum Disorder Using Magnetoencephalography Duan F, Watanabe K, Yoshimura Y, Kikuchi M, Minabe Y, Aihara K. PLoS One. 12 9 e0184422 2017/09
- Tele-Operating an Android Robot to Promote the Understanding of Facial Expressions and to Increase Facial Expressivity in Individuals With Autism Spectrum Disorder Kumazaki H, Muramatsu T, Yoshikawa Y, Matsumoto Y, Miyao M, Ishiguro H, Mimura M, Minabe Y, Kikuchi M. Am J Psychiatry. 174 9 904-905 2017/09
- Oxytocin Effects on Emotional Response to Others' Faces via Serotonin System in Autism: A Pilot Study Fukai M, Hirosawa T, Kikuchi M, Ouchi Y, Takahashi T, Yoshimura Y, Miyagishi Y, Kosaka H, Yokokura M, Yoshikawa E, Bunai T, Minabe Y. Psychiatry Res Neuroimaging. 267 45-50 2017/09
- Band-specific Atypical Functional Connectivity Pattern in Childhood Autism Spectrum Disorder Takahashi T, Yamanishi T, Nobukawa S, Kasakawa S, Yoshimura Y, Hiraishi H, Hasegawa C, Ikeda T, Hirosawa T, Munesue T, Higashida H, Minabe Y, Kikuchi M. Clin Neurophysiol. 128 8 1457-1465 2017/08
- Comprehensive Association Analysis of 27 Genes From the GABAergic System in Japanese Individuals Affected With Schizophrenia Balan S, Yamada K, Iwayama Y, Hashimoto T, Toyota T, Shimamoto C, Maekawa M, Takagai S, Wakuda T, Kameno Y, Kurita D, Yamada K, Kikuchi M, Hashimoto T, Kanahara N, Yoshikawa T. Schizophr Res. 185 33-40 2017/07
- A Pilot Study of Serotonergic Modulation After Long-Term Administration of Oxytocin in Autism Spectrum Disorder Hirosawa T, Kikuchi M, Ouchi Y, Takahashi T, Yoshimura Y, Kosaka H, Furutani N, Hiraishi H, Fukai M, Yokokura M, Yoshikawa E, Bunai T, Minabe Y. Autism Res. 10 5 821-828 2017/05
- The Lateral Occipito-temporal Cortex Is Involved in the Mental Manipulation of Body Part Imagery Kikuchi M, Takahashi T, Hirosawa T, Oboshi Y, Yoshikawa E, Minabe Y, Ouchi Y. Front Hum Neurosci. 11 181 2017/04
- Ammonium Acid Urate Urolithiasis in Anorexia Nervosa: A Case Report and Literature Review Fukai M, Hirosawa T, Nakatani H, Muramatsu T, Kikuchi M, Minabe Y. Clin Case Rep. 5 5 685-687 2017/03
- Clonazepam Improves Dopamine Supersensitivity in a Schizophrenia Patient: A Case Report Fukai M, Hirosawa T, Takahashi T, Kaneda R, Kikuchi M, Minabe Y. Ther Adv Psychopharmacol. 7 3 113-117 2017/03
- Prefrontal Oxygenation During Verbal Fluency and Cognitive Function in Adolescents With Bipolar Disorder Type II Ono Y, Kikuchi M, Nakatani H, Murakami M, Nishisaka M, Muramatsu T, Munesue T, Minabe Y. Asian J Psychiatr. 25 147-153 2017/02
- A Near-Infrared Spectroscopy Study on Cortical Hemodynamic Responses to Normal and Whispered Speech in 3- To 7-Year-Old Children Remijn GB, Kikuchi M, Yoshimura Y, Shitamichi K, Ueno S, Tsubokawa T, Kojima H, Higashida H, Minabe Y. J Speech Lang Hear Res. 60 2 465-470 2017/02
- Characteristics of Communication Among Japanese Children With Autism Spectrum Disorder: A Cluster Analysis Using the Children's Communication Checklist-2 Tanaka S, Oi M, Fujino H, Kikuchi M, Yoshimura Y, Miura Y, Tsujii M, Ohoka H. Clin Linguist Phon. 31 3 234-249 2017
- Atypical Development of the Central Auditory System in Young Children With Autism Spectrum Disorder Yoshimura Y, Kikuchi M, Hiraishi H, Hasegawa C, Takahashi T, Remijn GB, Oi M, Munesue T, Higashida H, Minabe Y, Kojima H. Autism Res. 9 11 1216-1226 2016/11
- Mu Rhythm Suppression Reflects Mother-Child Face-To-Face Interactions: A Pilot Study With Simultaneous MEG Recording Hasegawa C, Ikeda T, Yoshimura Y, Hiraishi H, Takahashi T, Furutani N, Hayashi N, Minabe Y, Hirata M, Asada M, Kikuchi M. Sci Rep. 6 34977 2016/10
- The Contribution of Increased Gamma Band Connectivity to Visual Non-Verbal Reasoning in Autistic Children: A MEG Study Takesaki N, Kikuchi M, Yoshimura Y, Hiraishi H, Hasegawa C, Kaneda R, Nakatani H, Takahashi T, Mottron L, Minabe Y. PLoS One. 11 9 e0163133 2016/09
- Synchrony of Auditory Brain Responses Predicts Behavioral Ability to Keep Still in Children With Autism Spectrum Disorder: Auditory-evoked Response in Children With Autism Spectrum Disorder Yoshimura Y, Kikuchi M, Hiraishi H, Hasegawa C, Takahashi T, Remijn GB, Oi M, Munesue T, Higashida H, Minabe Y. Neuroimage Clin. 12 300-5 2016/07
- Alterations in Phase-Related Prefrontal Activation During Cognitive Tasks and Nicotinic α4β2 Receptor Availability in Alzheimer's Disease Oboshi Y, Kikuchi M, Terada T, Yoshikawa E, Bunai T, Ouchi Y. J Alzheimers Dis. 53 3 817-30 2016/05
- Atypical Bilateral Brain Synchronization in the Early Stage of Human Voice Auditory Processing in Young Children With Autism Kurita T, Kikuchi M, Yoshimura Y, Hiraishi H, Hasegawa C, Takahashi T, Hirosawa T, Furutani N, Higashida H, Ikeda T, Mutou K, Asada M, Minabe Y. PLoS One. 11 4 e0153077 2016/04
- Enhanced Brain Signal Variability in Children With Autism Spectrum Disorder During Early Childhood Takahashi T, Yoshimura Y, Hiraishi H, Hasegawa C, Munesue T, Higashida H, Minabe Y, Kikuchi M. Version 2. Hum Brain Mapp. 37 3 1038-50 2016/03
- Magnetoencephalography in the Study of Children With Autism Spectrum Disorder Kikuchi M, Yoshimura Y, Mutou K, Minabe Y. Psychiatry Clin Neurosci. 70 2 74-88 2016/02
- Oxytocin for Male Subjects With Autism Spectrum Disorder and Comorbid Intellectual Disabilities: A Randomized Pilot Study Munesue T, Nakamura H, Kikuchi M, Miura Y, Takeuchi N, Anme T, Nanba E, Adachi K, Tsubouchi K, Sai Y, Miyamoto K, Horike S, Yokoyama S, Nakatani H, Niida Y, Kosaka H, Minabe Y, Higashida H. Front Psychiatry. 7 2 2016/01
- Erratum To: Association Study of H2AFZ With Schizophrenia in a Japanese Case-Control Sample Jitoku D, Yamamoto N, Iwayama Y, Toyota T, Miyagi M, Enokida T, Tasaka Y, Umino M, Umino A, Uezato A, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T. J Neural Transm (Vienna). 122 11 1619-20 2015/11
- Population-dependent Contribution of the Major Histocompatibility Complex Region to Schizophrenia Susceptibility Yamada K, Hattori E, Iwayama Y, Toyota T, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Mori N, Yoshikawa T. Schizophr Res. 168 1-2 444-9 2015/10
- Changes in Autistic Trait Indicators in Parents and Their Children With ASD: A Preliminary Longitudinal Study Hasegawa C, Kikuchi M, Yoshimura Y, Hiraishi H, Munesue T, Takesaki N, Higashida H, Oi M, Minabe Y, Asada M. Psychiatry Res. 228 3 956-7 2015/08
- Reduced Prefrontal Activation During Performance of the Iowa Gambling Task in Patients With Bipolar Disorder Ono Y, Kikuchi M, Hirosawa T, Hino S, Nagasawa T, Hashimoto T, Munesue T, Minabe Y. Psychiatry Res. 233 1 1-8 2015/07
- Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses Maekawa M, Yamada K, Toyoshima M, Ohnishi T, Iwayama Y, Shimamoto C, Toyota T, Nozaki Y, Balan S, Matsuzaki H, Iwata Y, Suzuki K, Miyashita M, Kikuchi M, Kato M, Okada Y, Akamatsu W, Mori N, Owada Y, Itokawa M, Okano H, Yoshikawa T. Biol Psychiatry. 78 2 116-25 2015/07
- Genetic Analysis of the Glyoxalase System in Schizophrenia Bangel FN, Yamada K, Arai M, Iwayama Y, Balan S, Toyota T, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Mori N, Itokawa M, Stork O, Yoshikawa T. Prog Neuropsychopharmacol Biol Psychiatry. 59 105-110 2015/06
- Association Study of H2AFZ With Schizophrenia in a Japanese Case-Control Sample Jitoku D, Yamamoto N, Iwayama Y, Toyota T, Miyagi M, Enokida T, Tasaka Y, Umino M, Umino A, Uezato A, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T. J Neural Transm (Vienna). 122 6 915-23 2015/06
- Unusual Developmental Pattern of Brain Lateralization in Young Boys With Autism Spectrum Disorder: Power Analysis With Child-Sized Magnetoencephalography Hiraishi H, Kikuchi M, Yoshimura Y, Kitagawa S, Hasegawa C, Munesue T, Takesaki N, Ono Y, Takahashi T, Suzuki M, Higashida H, Asada M, Minabe Y. Psychiatry Clin Neurosci. 69 3 153-60 2015/03
- Changes in EEG Complexity With Electroconvulsive Therapy in a Patient With Autism Spectrum Disorders: A Multiscale Entropy Approach Okazaki R, Takahashi T, Ueno K, Takahashi K, Ishitobi M, Kikuchi M, Higashima M, Wada Y. Front Hum Neurosci. 9 106 2015/02
- Attentional Control and Interpretation of Facial Expression After Oxytocin Administration to Typically Developed Male Adults Hirosawa T, Kikuchi M, Okumura E, Yoshimura Y, Hiraishi H, Munesue T, Takesaki N, Furutani N, Ono Y, Higashida H, Minabe Y. PLoS One. 10 2 e0116918 2015/02
- A Longitudinal Study of Auditory Evoked Field and Language Development in Young Children Yoshimura Y, Kikuchi M, Ueno S, Shitamichi K, Remijn GB, Hiraishi H, Hasegawa C, Furutani N, Oi M, Munesue T, Tsubokawa T, Higashida H, Minabe Y. Neuroimage. 101 440-7 2014/11
- Oxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics. Hirosawa T, Kikuchi M, Higashida H, Okumura E, Ueno S, Shitamichi K, Yoshimura Y, Munesue T, Tsubokawa T, Haruta Y, Nakatani H, Hashimoto T, Minabe Y. Scientific Reports 2 2012/04
- Algorithm for estimation of brain structural location from head surface shape in young children. Hayashi N, Kikuchi M, Sanada S, Minabe Y, Miyati T, Hachiman Y, Arishita T, Iida H, Matsui O. NEUROREPORT 28 299-303 2012/03
- A review of the default mode network in aging and dementia based on molecular imaging. Ouchi Y, Kikuchi M. Rev Neurosci. 28 263-8 2012/02
- Language performance and auditory evoked fields in 2- to 5-year-old children. Yoshimura Y, Kikuchi M, Shitamichi K, Ueno S, Remijn GB, Haruta Y, Oi M, Munesue T, Tsubokawa T, Higashida H, Minabe Y. EUROPEAN JOURNAL OF NEUROSCIENCE 35 644-50 2012/02
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- Hemodynamic responses to visual stimuli in cortex of adults and 3- to 4-year-old children. Remijn GB, Kikuchi M, Yoshimura Y, Shitamichi K, Ueno S, Nagao K, Munesue T, Kojima H, Minabe Y. Brain Res. 6 242-51 2011/04
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- Joint attention and intelligence in children with autism spectrum disorder without severe intellectual disability. Masuhiko Sano,Yuko Yoshimura,Tetsu Hirosawa,Chiaki Hasegawa,Kyung-Min An,Sanae Tanaka,Nobushige Naitou,Mitsuru Kikuchi Autism research : official journal of the International Society for Autism Research 14 12 2603 2021/08/23
- Kcns3 deficiency disrupts Parvalbumin neuron physiology in mouse prefrontal cortex: Implications for the pathophysiology of schizophrenia. Takeaki Miyamae,Takanori Hashimoto,Monica Abraham,Rika Kawabata,Sho Koshikizawa,Yufan Bian,Yosuke Nishihata,Mitsuru Kikuchi,G Bard Ermentrout,David A Lewis,Guillermo Gonzalez-Burgos Neurobiology of disease 155 105382 2021/07
- A common variant of CNTNAP2 is associated with sub-threshold autistic traits and intellectual disability Yuka Shiota,Tetsu Hirosawa,Yuko Yoshimura,Sanae Tanaka,Chiaki Hasegawa,Sumie Iwasaki,Kyung-min An,Daiki Soma,Masuhiko Sano,Shigeru Yokoyama,Mitsuru Kikuchi PLOS ONE 16 12 e0260548 2021/12/13
- Sleep maturation influences cognitive development of preterm toddlers. Akiko Ando,Hidenobu Ohta,Yuko Yoshimura,Machiko Nakagawa,Yoko Asaka,Takayo Nakazawa,Yusuke Mitani,Yoshihisa Oishi,Masato Mizushima,Hiroyuki Adachi,Yosuke Kaneshi,Keita Morioka,Rinshu Shimabukuro,Michio Hirata,Takashi Ikeda,Rika Fukutomi,Kyoko Kobayashi,Miwa Ozawa,Masahiro Takeshima,Atsushi Manabe,Tsutomu Takahashi,Kazuo Mishima,Isao Kusakawa,Hitoshi Yoda,Mitsuru Kikuchi,Kazutoshi Cho Scientific reports 11 1 15921 2021/08/05
- Expression of actin- and oxidative phosphorylation-related transcripts across the cortical visuospatial working memory network in unaffected comparison and schizophrenia subjects. Sohei Kimoto,Takanori Hashimoto,Kimberly J Berry,Makoto Tsubomoto,Yasunari Yamaguchi,John F Enwright,Kehui Chen,Rika Kawabata,Mitsuru Kikuchi,Toshifumi Kishimoto,David A Lewis Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2022/01/15
- Alteration of Neural Network Activity With Aging Focusing on Temporal Complexity and Functional Connectivity Within Electroencephalography Momo Ando,Sou Nobukawa,Mitsuru Kikuchi,Tetsuya Takahashi Frontiers in Aging Neuroscience 14 2022/02/04
- Effect of CNTNAP2 polymorphism on receptive language in children with autism Spectrum disorder without language developmental delay. Yuka Shiota,Tetsu Hirosawa,Yuko Yoshimura,Sanae Tanaka,Chiaki Hasegawa,Sumie Iwasaki,Masuhiko Sano,Kyung-Min An,Shigeru Yokoyama,Mitsuru Kikuchi Neuropsychopharmacology reports 2022/06/22
- Phantom eye syndrome after bilateral self-enucleation in a patient with schizophrenia. Makoto Tsubomoto,Shogo Miyashita,Mitsuru Kikuchi Psychiatry and clinical neurosciences 2022/05/24
Conference Presentations
- Social Brain and Mind Using Simultaneous MEG System.(conference：The 18th Mind Brain Conference)(2020/02)
- MEG measurement in young children with autism spectrum disorder.(conference：WAM 2019 Neurocognitive clinical applications of MEG: Present and future)(2019/12)
- Social brain study uisng simultaneous MEG system.(conference：International Society for the Advancement of Clinical MEG)(2019/09)
- Auditory Mismatch Field and Language Performance in Children Born Preterm.(conference：International Society for the Advancement of Clinical MEG)(2019/09)
- MEG research to elucidate the diversity in autism.(conference：Second international Symposium on Brain Science and MEG)(2019/06)
- Atypical development of the central auditory system in young children with Autism spectrum disorder.(conference：WFSBP Asia Pacific Regional Congress of Biological Psychiatry)(2018/09)
- Alpha band suppression during an interactive tapping task: A parent-child hyperscanning-MEG study.(conference：BIOMAG2018)(2018/08)
- Atypical brain development in young children with Autism spectrum disorder: child-customised MEG studies.(conference：1st Workshop on Brain Science and MEG)(2018/06)
- Atypical development of the central auditory system in young children with Autism spectrum disorder.(conference：CCD-KITMEGWorkshop)(2017/12)
- Challenge to the brain functional measurement during parent-child interaction(conference：INCF Japan Node International Workshop Advances in Neuroinformatics AINI 2017)(2017/11)
- Development of the central auditory system in typically developing young children and children with Autism spectrum disorder.(conference：Biomagnetic Sendai)(2017/05)
- Atypical brain activity in children with autism spectrum disorder.(conference：The 3rd International Symposium on Cognitive Neuroscience Robotics: Toward Constructive Developmental Science)(2016/12)
- Atypical development of the auditory system in children with autism spectrum disorder.(conference：The 20th International Conference on Biomagnetism (BIOMAG2016))(2016/10)
Others
- Heart rate variability in drug-naive patients with panic disorder and major depressive disorder. Hanaoka A, Kidani T, Remijn GB, Minabe Y, Munesue T, Koshino Y. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13;33(8):1474-8 2009
- Panic disorder with and without agoraphobia. Comorbidity within a half year of the onset of panic disorder. Komuro R, Oka H, Kidani T, Hanaoka A, Koshino Y. 59 639-643 2005
- Individual analysis of EEG band power and clinical drug response in schizophrenia. Wada Y, Higashima M, Nagasawa T, Takeda T, Koshino Y. 51 183-190 2005
- EEG harmonic responses to photic stimulation in normal aging and Alzheimer's disease: differences in interhemispheric coherence. Wada Y, Takeda T, Oe H, Hashimoto T, Koshino Y 113 1045-1051 2002
- Differences in EEG harmonic driving responses to photic stimulation between normal aging and Alzheimer's disease. Wada Y, Koshino Y 33 86-92 2002
- EEG changes following scopolamine administration in healthy subjects. Quantitative analysis during rest and photic stimulation Wada Y, Nanbu Y, Nakajima A, Tachibana H, Takeda T, Hashimoto T 39 219-226 1999
Arts and Fieldwork
Patent
Theme to the desired joint research
○Establishment of objective indicators in the psychiatric field (including developmental disorders)
○Practical application of brain function measurement using optical pumping magnetometer
○Evaluation of infant brain characteristics using an infant magnetoencephalography
Grant-in-Aid for Scientific Research
○Moonshot Research and Development Program 9「Protect children's curiosity and individuality and realize a dynamic society 」(2022-2024)
○Center of Innovation Program Acceleration Budget「Development of a healthy brain from infancy 」(2022-2022)
○Kanazawa University Top-down「Research on mental empowerment from early childhood 」(2022-2023)
○「Realizing a city that nurtures children's healthy minds by utilizing the individuality of the brain: A paradigm shift from peculiarity to specialty」(2013-2021)
○「The biomarker corresponding to the symptom variety in children with autism spectrum disorder. 」(2020-2022)
○「自閉スペクトラム症幼児の症状多様性に対応する生物学的指標の検討」(2017-2019)
○「注意欠陥・多動性障害における、幼児期の聴覚入力特性と「注意力」形成不全の関係」(2016-)
○「自閉症スペクトラム障害幼児における、知覚入力と「こころ」の形成過程の関係」(2014-2015)
○「自閉症スペクトラム障害幼児における遺伝子多型、脳内ネットワークと表現型の関係」(2014-2016)
○「広汎性発達障害の多様性を考慮した、広汎性発達障害児の早期介入効果の検討」
○「広汎性発達障害の兄弟研究による自他認知の発達の基盤にある知覚情報処理構造の解明」
○「小児における確率的脳座標の作成」(2011-2013)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Psychiatric Disorders and Treatments(2021)
Classes (Graduate Schools)
○General Psychiatry(2021)
○Integrated Nano Neuroscience(2021)
○Preventive Medicine(2021)
○Preventive Medicine(2020)
○General Psychiatry(2020)