Specialities

Legal medicine、Human pathology

Speciality Keywords

vascular wall tissue fragility,sudden death,atherosclerosis,experimental animals,establishment of preventive molecular suicidology

Research Themes

Books

• 　Hacker GW, Zuka M, Tubbs RR et. al.　Proteolytic activity demonstrated by film in situ zymography(FIZ): A novel double staining method also involving immunogold-silver staining.　CRC Press　2004/01

Papers

• 　Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream　Martin R. Weber*,Masahiko Zuka*,Mihaela Lorger,Mario Tschan,Bruce E. Torbett,Andries Zijlstra,James P. Quigley,Karin Staflin,Brian P. Eliceiri,Joseph S. Krueger,Patrizia Marchese,Zaverio M. Ruggeri,Brunhilde H. Felding * equally contributed　Thrombosis Research　140　S27　2016/04
• 　Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin.　Sho Amatsu,Takuhiro Matsumura,Masahiko Zuka,Yukako Fujinaga　The Journal of biological chemistry　299　3　102944　2023/03
• 　Cellular uptake and biotransformation of arsenate by freshwater phytoplankton under salinity gradient revealed by single-cell ICP-MS and CT-HG-AAS　Md Shah Alam, Shogo Fujisawa, Masahiko Zuka, Yinghan Zai, Asami S. Mashio, Ismail M. M. Rahman, Kuo H. Wong, Hiroshi Hasegawa　Environmental Chemistry　2023
• 　Significance of simultaneous measurement for lithium and strontium in various cavity-fluids of immersed bodies as potentially novel markers of drowning.　Takahiro Eida, Satoru Minabe, Asami Mashio, Takaya Murakami, Hirishi Hasegawa, and Masahiko Zuka　The Research and Practice in Forensic Medicine　65　35-43　2023/11/30
• 　Secretion of Pleiotrophin Stimulates Breast Cancer Progression through Remodeling of the Tumor Microevironment.　Chang Y, Zuka M, Perez-Pinera P, Deuel TF, et. al.　Proc Natl Acad Sci U S A　104　26　 10888-10893　2007/06

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Conference Presentations

• A case of unusual death due to stinging by Hymenoptera vespidae.(conference：24th Congress of the International Academy of Legal Medicine(IALM))(2018/06/08)

Others

• 　Fragility of Vascular Wall in Pathological microenvironment.　117　1　10-13　2008/01

Arts and Fieldwork

Patent

○Method of measurement for protease activity(publish date：2001/01/01)(No：2001-197)

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「ヒト大動脈・冠動脈硬化粥腫（プラーク）の脆弱化および安定化の分子機構に関する研究」(1999-2000)　
○「組織培養とFIZを用いたヒト動脈壁プロテアーゼ活性測定法による薬物治療効果の予測---副題 FIZ(:film in situ zymography)重染色法の動脈硬化症病変への応用」(2001-2002)　
○「能登半島地震における地震関連死」(2007-2007)　
○「肺組織で観察される単球系細胞の性状解析と法医診断」(2008-2010)　
○「能登半島地震における地震関連死」(2008-2008)　
○「能登半島地震における地震関連死」(2009-2009)　
○「ヒト血管壁における組織脆弱性評価の研究」(2011-2013)　
○「脳脊髄液の性状が脳動脈壁組織脆弱性に与える影響についての検討」(2014-2016)　
○「血管壁の極性とプロテアーゼ活性に着目した頭蓋内組織脆弱性の解析」(2018-2021)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Forensic medicine for the students of department of medicine(2020)
○Introduction to Region-studies(2020)
○Introduction to Medical Sciences(2020)
○Forensic medicine for the students of department of law(2020)
○Practice of Forensic Medicine(2020)
○Introduction to Medical Sciences(2019)
○Introduction to Region-studies(2019)
○Forensic medicine(2019)
○Practice of Forensic Medicine(2019)
○Introduction to Medical Sciences(2017)
○Legal Medicine(2017)
○Legal Medicine(2017)
○Introduction to Region-studies(2017)
○Legal Medicine(2016)
○Legal Medicine(2016)
○Introduction to Region-studies(2016)

Classes (Graduate Schools)

○Forensic Medicine for the students of law school(2019)
○BIOETHICS(2019)
○Forensic and Social Environmental Medicine(2019)
○Forensic and Social Environmental Medicine(2019)
○Fostering the Independence of Researchers(2019)
○Forensic Medicine for the students of law school(2018)
○Forensic Medicine(2017)
○BIOETHICS(2017)
○Forensic and Social Environmental Medicine(2017)
○Fostering the Independence of Researchers(2017)
○Forensic and Social Environmental Medicine(2017)
○Forensic and Social Environmental Medicine(2017)
○Introduction to Basic Medical Science(2016)
○Forensic and Social Environmental Medicine(2016)
○Forensic and Social Environmental Medicine(2016)
○BIOETHICS(2016)
○Forensic Medicine(2016)
○Forensic and Social Environmental Medicine(2016)