Associate Professor KONDO Satoru
Faculty, Affiliation
University Hospital
Assistant professor
College and School Educational Field
Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Academic Background
Career
Year & Month of Birth
Academic Society
Award
Specialities
Otorhinolaryngology
Speciality Keywords
Epstein-Barr virus、Human papillomavirus, nasopharyngeal cancer
Research Themes
Pathogenesis of EBV related nasopharyngeal cancer, Establishment of biomarker of nasopharyngeal cancer
Books
Papers
- EBV-LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer Cancer medicine 9 7663 7671 2020
- APOBEC3A associates with human papillomavirus genome integration in oropharyngeal cancers. Kondo S, Wakae K, Wakisaka N et al. Oncogene 2016
- Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell lines. Kondo S, Wakisaka N, Muramatsu M et al. J Virol. 2011
- Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling. Kondo S, Yoshizaki T, Wakisaka N et al. J Virol. 2007
- EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells. Kondo S, Seo SY, Yoshizaki T et al. Cancer Res. 2006
- Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma. Kondo S, Wakisaka N, Schell MJ et al. Int J Cancer 2005
- EBV-DNA quantification and antibody to viral capsid antigen in nasopharyngeal carcinoma patients. Kondo S, Horikawa T, Takeshita H et al. Cancer Sci. 2004
Conference Presentations
- Pathobiology of Epstein-Barr virus associated nasopharyngeal cancer(conference：2022 Sino-Japanese Academic Symposium)(2022/04/12)
- Synergistic effect of hypoxia condition and Epstein Barr virus latent membrane protein 1 enhence expression of Siah1 and HIF1-alfa in nasopahryngeal carcinoma patients. (conference：14th EBV International Conference)(2010)
- Epstein-Barr Virus Latent Membrane Protein 1 Initiates Cancer Progenitor Cells in Nasopharyngeal Cell Lines. (conference：6th International Symposium on Nasopharyngeal Carcinoma)(2013)
- The expression of Sparc in Epstein-Barr virus-associated nasopharyngeal carcinoma and its relation with cell competition. (conference：7th International Nasopharyngeal Carcinoma Biannual Meeting Symposium)(2015)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「EBウイルスによるDNAメチル化誘導機構の解明と新規上咽頭癌治療法の開発」(2021-2024)
○「新規生物学的コンセプトを応用した頭頸部ウイルス発癌超早期治療法の開発」(2021-2023)
○「内因性免疫による頭頸部ウイルス発癌における内分泌撹乱物質の関与と新規治療法の開発」(2016-2020)
○「シングルセル解析による次世代頭頸部癌個別化治療法の開発」(2016-2018)
○「代償性増殖による上咽頭癌発癌機構の解明と治療戦略」(2014-2018)
○「遺伝子マスターレギュレーターSATB1の頭頸部癌遺伝子発現制御機構」(2013-2015)
○「細胞競合現象に基づく上咽頭癌発癌機構の解析と新規治療法の開発」(2012-2015)
○「MDM2プロモーター遺伝子多型の上咽頭がんに対する関与」(2007-2008)
○「内因性免疫によるＥＢＶ感染制御機構と上咽頭癌発癌機構に関する研究」(2011-2015)
○「上咽頭がんをはじめとするEBV関連腫瘍におけるSiah1の分子生物学的解析」(2007-2010)
○「舌がん癌幹細胞の頸部リンパ節転移機構への関与」(2009-2011)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Central nervous system & Sensory Organs(2022)
○Central nervous system & Sensory Organs(2022)
○Central nervous system & Sensory Organs(2022)
○Central nervous system & Sensory Organs(2022)
Classes (Graduate Schools)
○General Otorhinolaryngology(2019)
○General Otorhinolaryngology(2018)
○General Otorhinolaryngology(2017)
○General Otorhinolaryngology(2016)
○General Otorhinolaryngology(2015)