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last modified：2025/04/01
Professor SHIMIZU Miho
Faculty, Affiliation
Health Service Center Department of Nephrology and Laboratory Medicine, Graduate School of Medical Sciences
Associate Professor
College and School Educational Field
Laboratory
Academic Background
【Degree】
M.D., Ph.D.
Career
Year & Month of Birth
Academic Society
Award
M.D., Ph.D.
M.D., Ph.D.
Specialities
Kidney internal medicine
Speciality Keywords
nephrology
Research Themes
Books
- Shimizu Miho, Wada Takashi Diabetic Kidney Disease Springer 2020/12
Papers
- Polar vasculosis is associated with better kidney outcome in type 2 diabetes with biopsy-proven diabetic kidney disease: A multicenter cohort study Shimizu M, Furuichi K, Toyama T, Yamanouchi M, Hoshino J, Kitajima S, Hara A, Iwata Y, Sakai N, Yuzawa Y, Kitamura H, Sato H, Shibagaki Y, Suzuki Y, Uesugi N, Ueda Y, Kohagura K, Samejima K, Tsuruya K, Nishi S, Nishino T, Makino H, Matsuo S, Ubara Y, Yokoyama H, Wada T J Diabetes Investig 14 11 1268-1278 2023/07/22
- Impact of the relationship between hemoglobin levels and renal interstitial fibrosis on long-term outcomes in type 2 diabetes with biopsy-proven diabetic nephropathy Shimizu M, Furuichi K, Kitajima S, Toyama T, Oshima M, Ogura H, Sato K, Nakagawa S, Yamamura Y, Miyagawa T, Hara A, Iwata Y, Sakai N, Kitagawa K, Yoshimura M, Yokoyama H, Wada T BMC Nephrol 22 1 319 2021/09/25
- Trajectories of kidney function in diabetes: a clinicopathological update Oshima M, Shimizu M, Yamanouchi M, Toyama T, Hara A, Furuichi K, Wada T Nat Rev Nephrol 17 11 740-750 2021/08/06
- Association of renal arteriosclerosis and hypertension with renal and cardiovascular outcomes in Japanese type 2 diabetic patients with diabetic nephropathy Shimizu M, Furuichi K, Toyama T, Funamoto T, Kitajima S, Hara A, Iwata Y, Sakai N, Takamura T, Kitagawa K, Yoshimura M, Kaneko S, Yokoyama H, Wada T J Diabetes Investig 10 4 1041-1049 2019/01/18
- Decline in estimated glomerular filtration rate is associated with risk of end-stage renal disease in type 2 diabetes with macroalbuminuria: an observational study from JDNCS Shimizu M, Furuichi K, Toyama T, Funamoto T, Kitajima S, Hara A, Ogawa D, Koya D, Ikeda K, Koshino Y, Kurokawa Y, Abe H, Mori K, Nakayama M, Konishi Y, Samejima KI, Matsui M, Yamauchi H, Gohda T, Fukami K, Nagata D, Yamazaki H, Yuzawa Y, Suzuki Y, Fujimoto S, Maruyama S, Kato S, Naito T, Yoshimura K, Yokoyama H, Wada T Clin Exp Nephrol 22 2 377-387 2017/09/09
- Serum autotaxin levels are associated with proteinuria and kidney lesions in Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy Shimizu M, Furuichi K, Toyama T, Yamahana J, Ohkawa R, Igarashi K, Aoki J, Kaneko S, Yatomi Y, Wada T Intern Med 55 3 215-221 2016/02/01
- Long-term outcomes of Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy Shimizu M, Furuichi K, Toyama T, Kitajima S, Hara A, Kitagawa K, Iwata Y, Sakai N, Takamura T, Yoshimura M, Yokoyama H, Kaneko S, Wada T Diabetes Care 36 11 3655-3662 2013/10/02
- Kidney lesions in diabetic patients with normoalbuminuric renal insufficiency Shimizu M, Furuichi K, Yokoyama H, Toyama T, Iwata Y, Sakai N, Kaneko S, Wada T Clin Exp Nephrol 18 2 305-312 2013/10/01
- Two-year longitudinal trajectory patterns of albuminuria and subsequent rates of end-stage kidney disease and all-cause death: a nationwide cohort study of biopsy-proven diabetic kidney disease Yamanouchi M, Furuichi K, Hoshino J, Toyama T, Shimizu M, Yamamura Y, Oshima M, Kitajima S, Hara A, Iwata Y, Sakai N, Oba Y, Matsuoka S, Ikuma D, Mizuno H, Suwabe T, Sawa N, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ueda Y, Nishi S, Yokoyama H, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Makino H, Matsuo S, Ubara Y, Wada T BMJ Open Diabetes Res Care 9 1 e002241 2021/08/12
- Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes Oshima M, Toyama T, Hara A, Shimizu M, Kitajima S, Iwata Y, Sakai N, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T BMJ Open Diabetes Res Care 9 1 e002311 2021/05/29
- Serum hemoglobin concentration, as a reflection of renal fibrosis, and risk of renal decline in early-stages of diabetic kidney disease: a nationwide, biopsy-based cohort study Yamanouchi M, Furuichi K, Shimizu M, Toyama T, Yamamura Y, Oshima M, Kitajima S, Hara A, Iwata Y, Sakai N, Oba Y, Matsuoka S, Ikuma D, Mizuno H, Suwabe T, Hoshino J, Sawa N, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ueda Y, Nishi S, Yokoyama H, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Makino H, Matsuo S, Ubara Y, Wada T Nephrol Dial Transplant 37 3 489-497 2021/05/24
- Clinico-pathological features of kidney disease in diabetic cases Furuichi K, Shimizu M, Okada H, Narita I, Wada T Clin Exp Nephrol 22 5 1046-1051 2018/03/21
- A new pathological scoring system by the Japanese classification to predict renal outcome in diabetic nephropathy Hoshino J, Furuichi K, Yamanouchi M, Mise K, Sekine A, Kawada M, Sumida K, Hiramatsu R, Hasegawa E, Hayami N, Suwabe T, Sawa N, Hara S, Fujii T, Ohashi K, Kitagawa K, Toyama T, Shimizu M, Takaichi K, Ubara Y, Wada T PLoS One 13 2 e0190923 2018/02/06
- Diabetic nephropathy: A comparison of the clinical and pathological features between the CKD risk classification and the classification of diabetic nephropathy 2014 in Japan Furuichi K, Shimizu M, Hara A, Toyama T, Wada T Intern Med 57 23 3345-3350 2018/12/01
- Nonproteinuric versus proteinuric phenotypes in diabetic kidney disease: A propensity score-matched analysis of a nationwide, biopsy-based cohort study Yamanouchi M, Furuichi K, Hoshino J, Toyama T, Hara A, Shimizu M, Kinowaki K, Fujii T, Ohashi K, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Mise K, Makino H, Matsuo S, Ubara Y, Wada T Diabetes Care 42 5 891-902 2019/03/04
- Amplified association between blood pressure and albuminuria in overweight patients with biopsy-proven hypertensive nephrosclerosis Kohagura K, Furuichi K, Kochi M, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hoshino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T Am J Hypertens 32 5 486-491 2019/04/22
- Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes Oshima M, Toyama T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Hara A, Makino H, Wada T PLoS One 13 8 e0201535 2018/08/02
- Clinicopathological predictors for progression of chronic kidney disease in nephrosclerosis: a biopsy-based cohort study Yamanouchi M, Hoshino J, Ubara Y, Takaichi K, Kinowaki K, Fujii T, Ohashi K, Mise K, Toyama T, Hara A, Shimizu M, Furuichi K, Wada T Nephrol Dial Transplant 34 7 1182-1188 2018/05/19
- Value of adding the renal pathological score to the kidney failure risk equation in advanced diabetic nephropathy Yamanouchi M, Hoshino J, Ubara Y, Takaichi K, Kinowaki K, Fujii T, Ohashi K, Mise K, Toyama T, Hara A, Kitagawa K, Shimizu M, Furuichi K, Wada T PLoS One 13 1 e0190930 2018/01/16
- Nationwide multicenter kidney biopsy study of Japanese patients with hypertensive nephrosclerosis Furuichi K, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hoshino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T; Research Group of Diabetic Nephropathy and Nephrosclerosis, Ministry of Health, Labour and Welfare of Japan, and Japan Agency for Medical Research and Development Clin Exp Nephrol 22 3 629-637 2017/11/11
- Clinicopathological analysis of biopsy-proven diabetic nephropathy based on the Japanese classification of diabetic nephropathy Furuichi K, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hohino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Makino H, Matsuo S, Wada T; Research Group of Diabetic Nephropathy, Ministry of Health, Labour and Welfare of Japan, and Japan Agency for Medical Research and Development Clin Exp Nephrol 22 3 570-582 2017/10/27
- Clinical and pathological significance of autoantibodies to erythropoietin receptor in type 2 diabetic patients with chronic kidney disease Hara A, Furuichi K, Koshino A, Yasuda H, Tran TTT, Iwata Y, Sakai N, Shimizu M, Kaneko S, Nakamura H, Wada T Kidney International Reports 2017/09/08
- Nationwide multicentre kidney biopsy study of Japanese patients with type 2 diabetes Furuichi K, Yuzawa Y, Shimizu M, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T Nephrol Dial Transplant 33 1 138-148 2017/03/02
- Relationship between Serum Uric Acid Levels and Chronic Kidney Disease in a Japanese Cohort with Normal or Mildly Reduced Kidney Function Toyama T, Furuichi K, Shimizu M, Hara A, Iwata Y, Sakai N, Perkovic V, Kobayashi M, Mano T, Kaneko S, Wada T PLoS One 10 9 e0137449 2015/09/10
- Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H; The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Clin Exp Nephrol 18 4 613-620 2013/10/17
- Treatment and impact of dyslipidemia in diabetic nephropathy Toyama T, Shimizu M, Furuichi K, Kaneko S, Wada T Clin Exp Nephrol 18 2 201-205 2013/11/07
- Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation Furuichi K, Shimizu M, Toyama T, Koya D, Koshino Y, Abe H, Mori K, Satoh H, Imanishi M, Iwano M, Yamauchi H, Kusano E, Fujimoto S, Suzuki Y, Okuda S, Kitagawa K, Iwata Y, Kaneko S, Nishi S, Yokoyama H, Ueda Y, Haneda M, Makino H, Wada T Clin Exp Nephrol 17 6 819-826 2013/02/28
- Nodular lesions and mesangiolysis in diabetic nephropathy Wada T, Shimizu M, Yokoyama H, Iwata Y, Sakai Y, Kaneko S, Furuichi K Clin Exp Nephrol 17 1 3-9 2012/10/26
- Clinical impact of albuminuria in diabetic nephropathy Wada T, Shimizu M, Toyama T, Hara A, Kaneko S, Furuichi K Clin Exp Nephrol 16 1 96-101 2011/08/10
- Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats Furuichi K, Hisada Y, Shimizu M, Okumura T, Kitagawa K, Yoshimoto K, Iwata Y, Yokoyama H, Kaneko S, Wada T Nephrol Dial Transplant 26 10 3124-3131 2011/03/17
- Propagermanium administration for patients with type 2 diabetes and nephropathy: A randomized pilot trial Hara A, Shimizu M, Hamaguchi E, Kakuda H, Ikeda K, Okumura T, Kitagawa K, Koshino Y, Kobayashi M, Takasawa K, Hisada Y, Toyama T, Iwata Y, Sakai N, Wada T Endocrinol Diabetes Metab 3 3 e00159 2020/06/12
- Clinicopathological features of fast eGFR decliners among patients with diabetic nephropathy Furuichi K, Shimizu M, Yamanouchi M, Hoshino J, Sakai N, Iwata Y, Toyama T, Kitajima S, Hara A, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ueda Y, Nishi S, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Makino H, Matsuo S, Ubara Y, Yokoyama H, Wada T BMJ Open Diabetes Res Care 8 1 e001157 2020/06
Conference Presentations
- Clinicopathological risk factors for the prognosis of diabetic nephropathy in Japanese patients with type 2 diabetes(conference：American Diabetes Association’s 72nd Scientific Sessions)(2012/06/09)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「糸球体門部小血管増生に着目した糖尿病性腎臓病の進展抑制機序の解明」(2023-2026)
○「糖尿病性腎症におけるアミノ酸光学異性体発現の臨床的意義」(2017-2020)
○「腎疾患におけるリゾリン脂質産生酵素（ATX，PS-PLA1）の臨床的意義の解明」(2014-2016)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Clinical Clerkship（Laboratory Medicine）(2023)
○Clinical Clerkship（Laboratory Medicine）(2023)
○Clinical Clerkship（Laboratory Medicine）(2023)
○Clinical Clerkship（Laboratory Medicine）(2023)
○Nephrology(2023)
○Laboratory Medicine(2023)
○Laboratory Medicine(2023)
○Nephrology(2022)
○Nephrology(2022)
○Kidney， Urogenital Organ & Male Genital Organ(2017)
Classes (Graduate Schools)
○Preventive Medicine(2023)
○Introduction to MedicineⅡ(2023)
○Preventive Medicine(2022)
○Preventive Medicine(2021)
○Preventive Medicine(2020)
○Preventive Medicine(2019)
○Preventive Medicine(2018)