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Researcher Information

last modified：2024/01/08

Professor　SUZUKI, Takeshi

Mail Laboratory Website

Faculty, Affiliation

Cancer Research Institute

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Division of Natural Sciences, Graduate School of Natural Science and Technology
Division of Transdisciplinary Sciences,Graduate School of Frontier Science Initiative
Division of Medicine, Graduate School of Medical Science
Division of Natural System, Graduate School of Natural Science and Technology
Course in Biosystems, School of Biological Science and Technology, College of Science and Engineering

Laboratory

Division of Functional Genomics　TEL:076-265-2734　FAX:076-234-4502

Academic Background

【Academic background(Doctoral/Master's Degree)】
The University of Tokyo　Doctor　Graduate School, Division of Science　199303　Completed
【Academic background(Bachelor's Degree)】
The University of Tokyo　198803
【Degree】
Ph. D.

Career

Research Associate(1993/04/01-1999/05/31)
Research Fellow　Research Fellow(1999/06/01-2003/03/31)
Associate Professor(2003/04/01-2007/03/31)

Year & Month of Birth

1966/11

Academic Society

Japanese Cancer Association
The Molecular Biology Society of Japan

Award

Specialities

Molecular biology、Cell biology、General medical chemistry、Virology

Speciality Keywords

Tumor virus, Oncogene, Genome informatics

Research Themes

Identification of novel cancer genes using retroviral insertional mutagenesis

Books

Papers

  • 　Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice　Suzuki T, Minehata K, Akagi K, Jenkins NA, Copeland NG　EMBO JOURNAL　25　14　3411-3421　2006/07
  • 　meis1 regulates the development of endothelial cells in zebrafish　Ken-ichi Minehata, Atsuo Kawahara, Takeshi Suzuki　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　374　4　647-652　2008/10
  • 　Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene　Akihiko Ishimura, Minoru Terashima, Hiroshi Kimura, Keiko Akagi, Yutaka Suzuki, Sumio Sugano, Takeshi Suzuki　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　389　366-371　2009/11
  • 　The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase　Minoru Terashima, Akihiko Ishimura, Masakazu Yoshida, Yutaka Suzuki, Sumio Sugano, Takeshi Suzuki　BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　399　238-244　2010/08
  • 　PLU1 histone demethylase decreases the expression of KAT5 and enhances the invasive activity of the cells　Masakazu Yoshida, Akihiko Ishimura, Minoru Terashima, Zanabazar Enkhbaatar, Naohito Nozaki, Kenji Satou, Takeshi Suzuki　BIOCHEMICAL JOURNAL　437　555-564　2011/08

show all

  • 　High-throughput retroviral tagging for identification of genes involved in initiation and progression of mouse splenic marginal zone lymphomas.　Shin MS, Fredrickson TN, Hartley JW, Suzuki T, Akagi K, Morse HC　CANCER RESEARCH　64　13　4419-27　2004/07
  • 　Early B-cell factor-associated zinc-finger gene is a frequent target of retroviral integration in murine B-cell lymphomas.　Warming S, Suzuki T, Yamaguchi TP, Jenkins NA, Copeland NG　ONCOGENE　23　15　2727-31　2004/04
  • 　RTCGD: retroviral tagged cancer gene database.　Akagi K, Suzuki T, Stephens RM, Jenkins NA, Copeland NG　NUCLEIC ACIDS RESEARCH　32　D　523-7　2004/01
  • 　Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.　Kelly J, Spolski R, Kovanen P, Suzuki T, Bollenbacher J, Pise-Masison C, Radonovich M, Lee S, Jenkins NA, Copeland NG, Morse HC, Leonard W　JOURNAL OF EXPERIMENTAL MEDICINE　198　1　79-89　2003/07
  • 　Transactivation of the Fucosyltransferase VII gene by human T-cell leukemia virus type I Tax through a variant cAMP-responsive element.　Hiraiwa N, Yabuta T, Yoritomi K, Hiraiwa M, Tanaka Y, Suzuki T, Yoshida M, Kannagi R　BLOOD　101　9　3615-21　2003/05
  • 　Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related kruppel-like zinc finger protein.　Warming S, Liu P, Suzuki T, Akagi K, Lindtner S, Pavlakis G, Jenkins NA, Copeland NG　BLOOD　101　5　1934-40　2003/03
  • 　Genome-based identification of cancer genes by proviral tagging in mouse retrovirus induced T-cell lymphoma.　Kim R, Trubetskoy A, Suzuki T, Jenkins NA, Copeland NG, Lenz J　JOURNAL OF VIROLOGY　77　3　2056-62　2003/02
  • 　Common sites of retroviral integration in mouse hematopoietic tumors identified by high-throughput, single nucleotide polymorphism-based, mapping and bacterial artificial chromosome hybridization.　Shen H, Suzuki T, Munroe DJ, Stewart C, Rasmussen L, Gilbert DJ, Jenkins NA, Copeland NG　JOURNAL OF VIROLOGY　77　2　1584-8　2003/01
  • 　New genes involved in cancer identified by retroviral tagging.　Suzuki T, Shen H, Akagi K, Morse HC, Malley JD, Naiman DQ, Jenkins NA, Copeland NG　NATURE GENETICS　32　1　166-74　2002/09

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

○Identification of novel molecular targets that interact with cancer genes

Grant-in-Aid for Scientific Research

○「ゲノムへの挿入変異を利用した疾患関連遺伝子の単離とその機能解析」(2009-2011)　
○「白血病ウイルス感染による病原性発現に関与する細胞性因子の解析」(2009-2010)　
○「ゲノムへの挿入変異を利用した疾患関連遺伝子の単離とその機能解析」(2009-)　
○「白血病ウイルス感染による病原性発現に関与する細胞性因子の解析」(2009-)　
○「ゲノム不安定性を示すマウスを利用した新しいがん抑制遺伝子の単離とその機能解析」(2009-)　
○「両アリルへの挿入変異導入を利用した疾患原因遺伝子の単離と機能解析」(2008-)　
○「ゲノム不安定性を示すマウスを利用した新しいがん抑制遺伝子の単離とその機能解析」(2008-)　
○「白血病ウイルス感染による病原性発現に関わる細胞性因子の同定と解析」(2008-)　
○「両アリルへの挿入変異導入を利用した疾患原因遺伝子の単離と機能解析」(2007-)　
○「白血病ウイルス感染による病原性発現に関わる細胞性因子の同定と解析」(2007-)　
○「ウイルス挿入変異法で同定されたエピゲノム制御因子による疾患発症機構の解析」(2012-2014)　

Competitive research funding,Contribution

Collaborative research,Consignment study

○Functional analysis of Jmjd5 candidate cancer gene identified by retroviral insertional mutagenesis(2010-2011)
○Functional analysis of Jmjd5 candidate cancer gene identified by retroviral insertional mutagenesis(2009-)

Classes (Bachelors)

Classes (Graduate Schools)

○Cancer molecular pathology 1(2017)
○Tumor Virology(2017)
○Tumor Virology(2017)
○Environment and Health -Introductory(2017)
○Biology of Cancer 1B(2017)
○Biology of Cancer 1A(2017)
○Cancer molecular pathology 1(2017)
○Tumor Virology(2017)
○Cancer molecular pathology 1(2017)
○Cancer molecular pathology 1(2017)
○Molecular Oncology(2017)
○Cancer molecular pathology 1(2016)
○Tumor Virology(2016)
○Tumor Virology(2016)
○Environment and Health -Introductory(2016)
○Tumor Virology(2016)
○Biology of Cancer 1B(2016)
○Biology of Cancer 1A(2016)
○Molecular Oncology(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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